1CSBB

Crystal structure of cathepsin b inhibited with ca030 at 2.1 angstroms resolution: a basis for the design of specific epoxysuccinyl inhibitors
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
205
structure length
205
Chain Sequence
VSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of cathepsin B inhibited with CA030 at 2.0-A resolution: A basis for the design of specific epoxysuccinyl inhibitors.
pubmed doi rcsb
molecule keywords CATHEPSIN B light chain
molecule tags Hydrolase/hydrolase inhibitor
total genus 46
structure length 205
sequence length 205
chains with identical sequence E
ec nomenclature ec 3.4.22.1: Cathepsin B.
pdb deposition date 1994-12-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1csbB00
5CVNB 1PXVA 2AYNA 4FJCA 1GECE 2NQIA 1VJVA 2E00A 2FRAA 5EGWA 4K7CA 4P6GA 1THEA 4OEMA 2G6DA 2XU4A 2YJBA 1QDQA 2ARYA 1SP4B 2R9MA 2B1NA 1GLOA 2H7JA 3QJ3A 3I06A 2NQGA 4BS6A 1PPNA 2F7DA 5EF4A 2BDZA 2ATOA 4N8WA 4QH6A 1ATKA 1AYUA 2YJ2A 3IMAA 3KW9A 1CSBB 3RVWA 3IUTA 4CDEB 3HHIA 4X6HA 4W5CA 2YJCA 1Y08A 3KSEA 1VSNA 1ITOA 4PADA 1POPA 2O6XA 1Q6KA 3O1GA 4QRVA 4W5BA 1YK7A 2JQFR 2F1GA 2HD5A 1MHWA 4DMXA 1CQDA 4YYQA 3OISA 1GMYA 4QRXA 1BGOA 1K3BB 1PADA 2DCBA 1QXPA 3S3QA 4BS5A 2GHUA 4KLBA 3BCNA 1M6DA 2AS8A 2BDLA 3H8BA 3QT4A 1KFUL 3F75A 3P5UA 4YYRA 4N79A 1STFE 4PI3A 1X9YA 1PPPA 2PNSA 4I04A 3K9MA 2R9NA 1KXRA 3PDFA 2YJ9A 4QRGA 1SNKA 3GCBA 3IV2A 4WA6A 4I05A 1ICFA 3K24A 4AXLA 1AU0A 4YYUA 1F29A 4CZWA 3PBHA 1YVBA 3HWNA 4ZUXU 3V6EA 1F2CA 3N3GA 4DMYA 2DZZA 5A24A 1S4VA 1EWMA 3H8CA 2AUXA 1EWOA 3WXFA 1YK8A 4MSXA 1ME4A 2AU1A 5PADA 1MEMA 3BPFA 3D6SA 2XU5A 1AU3A 3LFYA 4MZOA 2P0RA 5F02A 2Y6EA 1PIPA 2P86A 5CHVA 2R9CA 1O0EA 4RY2A 2NQDB 3ZUAA 1NLJA 3PNRA 4N4ZA 2DCDA 1EF7A 3P5XA 1BP4A 2VHSA 1ZIVA 3KFQA 2DC7A 1AYVA 3KKUA 3MHHA 2HH5A 3IEJA 2E02A 1PBHA 2FQ9A 1KHPA 1CPJA 1PCIA 1EWLA 1ME3A 1AIMA 2G7YA 4BQVA 2JQGR 5J94A 3O0UA 1F2BA 3OF8A 1PPDA 3HHAA 5FPWA 6PADA 5JH3A 2Y5BA 1PPOA 3BPMA 3P5WA 3DF0A 3C9EA 3RVXA 2VHFA 5JA7A 5CVOB 3WXGA 3TNXA 3CH2X 4CDDB 3AI8A 3HD3A 1XKGA 2R9FA 1JQPA 2FUDA 2R6NA 2DC8A 3H7DA 4YVAA 3N3KA 3S3RA 4XUIA 1NB3A 1QOLA 2FO5A 3U8EA 1CV8A 2DC6A 1CS8A 1MDWA 4PP1A 1CVZA 2R9OA 1TL9A 4X6IA 1FH0A 5CHTA 3H6SA 3K8UA 2XU3A 1YT7A 2ACTA 3KWZA 4YYWA 2AYOA 1MS6A 1CJLA 3IOQA 2PADA 4HWYA 3MORA 1IWDA 3CBJA 4G54A 3MHSA 5K16A 2G8JA 1AU2A 4MZSA 2HXZA 1U9WA 2GFOA 3E1ZB 1EWPA 2AVWA 3ERVA 4QBBA 1PE6A 8PCHA 2E01A 4YYSA 1U9VA 1U9XA 3IHPA 2OZ2A 3V6CA 1A6RA 1MEGA 3RVVA 1BQIA 2FT2A 3OVZA 3NHEA 2DCAA 1CB5A 1AECA 4W4UA 3CBKA 1CTEA 4X6JA 3OVXA 3BC3A 4P6EA 2OP3A 3M99A 3MTNA 2B1MA 4Q8HA 2PBHA 4CDFB 2C0YA 1KFXL 1BY8A 1F2AA 2CB5A 1U5IA 1AU4A 4FIPA 1ZCMA 2G8EA 4BSQA 3BWKA 3F5VA 3QSDA 2AIMA 1U9QX 4I07A 2FRQA 3N4CA 1Y4HA 3PW3A 2IBIA 9PAPA 4AXMA 3OF9A 2DC9A 3CH3X 1KHQA 2DZYA 2XU1A 4PP2E 2DJGB 3WXEA 2HHNA 4Q8GA 1NB5A 2AUZA 2WBFX 3B79A 3KX1A 4YYVA 3P5VA 2CIOA 2P7UA 1AYWA 4FK5A 2YJ8A 1QMYA 2FTDA 1GCBA 2DJFB 4CDCB 1YALA 1NL6A 3LXSA 4XR7A 2NQAA 4YV8A 3BOWA 2DCCA 2E03A 2PREA 4OELA 1TLOA 1NQCA 1NPZA 7PCKA 3I3TA 4BPVA 2FYEA 2IPPB 3H89A 3KWBX 1MIRA 5CVMA 3USVA 1DEUA 1DF0A 2OULA 1TU6A 1HUCB
chains in the Genus database with same CATH superfamily
1UKFA 5CVNB 1PXVA 4ZTBA 2AYNA 4FJCA 3MP2A 3W31A 1GECE 2NQIA 3PHUA 1VJVA 2E00A 2FRAA 5EGWA 4K7CA 4P6GA 1THEA 4OEMA 2G6DA 2XU4A 2YJBA 1QDQA 2ARYA 1SP4B 2R9MA 2B1NA 1GLOA 2UZJA 2H7JA 3QJ3A 3I06A 2NQGA 4BS6A 4XZXA 1PPNA 2F7DA 5EF4A 2BDZA 2ATOA 4N8WA 3E9SA 4QH6A 1ATKA 1AYUA 2YJ2A 3IMAA 3KW9A 1CSBB 3RVWA 3IUTA 4CDEB 3HHIA 4X6HA 4W5CA 2YJCA 1Y08A 3KSEA 1VSNA 1ITOA 4PADA 1POPA 2O6XA 1Q6KA 3O1GA 4QRVA 4W5BA 1YK7A 2JQFR 2F1GA 2HD5A 3PHWA 1MHWA 4DMXA 1CQDA 4YYQA 3OISA 1GMYA 4QRXA 1BGOA 1K3BB 1PADA 2DCBA 1QXPA 3S3QA 4BS5A 2GHUA 4KLBA 3BCNA 1M6DA 2AS8A 2BDLA 3H8BA 3QT4A 4GUAA 1KFUL 3F75A 3P5UA 4YYRA 3C0RA 2DOSA 4N79A 1STFE 4PI3A 1X9YA 1PPPA 2PNSA 4R3DA 4I04A 3K9MA 2R9NA 1KXRA 3PDFA 4M0WA 2YJ9A 4QRGA 4BOSA 3O65A 1SNKA 1DKIA 3GCBA 3PRMA 5EZSA 3IV2A 4WA6A 4I05A 4BOPA 1ICFA 3K24A 4AXLA 1AU0A 4YYUA 1F29A 4CZWA 3PBHA 1YVBA 4A5UA 3HWNA 4ZUXU 3V6EA 1F2CA 3N3GA 4DMYA 2DZZA 5A24A 1S4VA 1EWMA 3H8CA 2AUXA 1EWOA 3MJ5A 3WXFA 1YK8A 4MSXA 1ME4A 2AU1A 5PADA 1MEMA 3BPFA 3D6SA 2JTCA 2XU5A 1AU3A 3LFYA 2J7QC 4MZOA 2P0RA 5F02A 2Y6EA 1PIPA 2P86A 5CHVA 2R9CA 1O0EA 4RY2A 2NQDB 3MTVA 3ZUAA 1NLJA 5E6JA 3PNRA 4N4ZA 3ZNHA 2DCDA 1EF7A 3PSEA 3P5XA 2AGAA 1BP4A 2VHSA 1ZIVA 3KFQA 2DC7A 1AYVA 3KKUA 4RNAA 3MHHA 3PT2A 2HH5A 3TRKA 3IEJA 2BU3A 2E02A 1PBHA 2FQ9A 1KHPA 1CPJA 1PCIA 1EWLA 1ME3A 1AIMA 2G7YA 4BQVA 2JQGR 5J94A 2BTWB 3O0UA 1F2BA 3OF8A 1PPDA 3HHAA 5FPWA 6PADA 5JH3A 2Y5BA 1PPOA 3BPMA 3P5WA 2BTWA 3DF0A 4OW0A 3C9EA 3RVXA 2VHFA 5JA7A 4D8EA 5CVOB 3WXGA 3TNXA 3CH2X 4CDDB 3AI8A 3HD3A 1XKGA 2R9FA 1JQPA 2FUDA 2R6NA 4OVZB 2DC8A 3H7DA 4YVAA 3N3KA 3S3RA 4XUIA 1NB3A 1QOLA 2FO5A 3U8EA 1CV8A 2DC6A 1CS8A 1MDWA 2FE8A 4PP1A 1CVZA 2R9OA 1TL9A 4X6IA 3B21A 1FH0A 5CHTA 3H6SA 3PHXA 3K8UA 2XU3A 4OVZA 1YT7A 2ACTA 3KWZA 4YYWA 5JZEA 2AYOA 1MS6A 1CJLA 3IOQA 2PADA 4HWYA 3MORA 1IWDA 3CBJA 1YZBA 4G54A 3MHSA 5K16A 2G8JA 1AU2A 3IFUA 4MZSA 2HXZA 4HXDB 3OQCA 1U9WA 2GFOA 3E1ZB 1EWPA 2AVWA 4P16A 3ERVA 4QBBA 1PE6A 8PCHA 2E01A 4YYSA 1U9VA 2JRIA 1U9XA 3IHPA 4IUMA 2OZ2A 3V6CA 4BOQA 1A6RA 3BY4A 1MEGA 3RVVA 4MI7A 1BQIA 2FT2A 3OVZA 3NHEA 2DCAA 3RNVA 5KO3A 1CB5A 4RF1A 1AECA 4W4UA 3CBKA 1CTEA 4X6JA 3OVXA 4BOUA 4IP3A 3BC3A 4P6EA 2OP3A 3M99A 3MTNA 2B1MA 3BB7A 4Q8HA 2PBHA 4CDFB 2C0YA 3W30A 1KFXL 1BY8A 1F2AA 2CB5A 1U5IA 1AU4A 4FIPA 1ZCMA 2G8EA 4BSQA 3BWKA 3F5VA 3QSDA 2AIMA 1U9QX 4I07A 2FRQA 3N4CA 1Y4HA 3PW3A 2IBIA 9PAPA 4AXMA 3OF9A 2DC9A 3CH3X 1KHQA 2J7QA 3PRPA 2DZYA 5EZQA 2XU1A 4PP2E 2DJGB 4D8IA 3WXEA 2HHNA 2HWKA 4Q8GA 1NB5A 2AUZA 2WBFX 3B79A 3KX1A 4YYVA 4MM3B 4RKXA 3P5VA 2CIOA 3BBAA 2P7UA 1AYWA 4FK5A 2YJ8A 1QMYA 2FTDA 1GCBA 2DJFB 4CDCB 1YALA 1NL6A 3LXSA 4XR7A 2NQAA 4YV8A 4WURA 4BOZA 4PT5A 3BOWA 2DCCA 2E03A 2PREA 4RF0A 4D8BA 1PVJA 4REZA 4OELA 1TLOA 1NQCA 1NPZA 7PCKA 3I3TA 4BPVA 2FYEA 2Z84A 3TMPA 2IPPB 3H89A 3KWBX 1MIRA 5CVMA 3USVA 1DEUA 1DF0A 2OULA 1TU6A 1HUCB
chains in the Genus database with same CATH topology
5CVNB 1PXVA 2AYNA 4FJCA 1GECE 2NQIA 1VJVA 2E00A 2FRAA 5EGWA 4K7CA 4P6GA 1THEA 4OEMA 2G6DA 2XU4A 2YJBA 1QDQA 2ARYA 1SP4B 2R9MA 2B1NA 1GLOA 2H7JA 3QJ3A 3I06A 2NQGA 4BS6A 1PPNA 2F7DA 5EF4A 2BDZA 2ATOA 4N8WA 4QH6A 1ATKA 1AYUA 2YJ2A 3IMAA 3KW9A 1CSBB 3RVWA 3IUTA 4CDEB 3HHIA 4X6HA 4W5CA 2YJCA 1Y08A 3KSEA 1VSNA 1ITOA 4PADA 1POPA 2O6XA 1Q6KA 3O1GA 4QRVA 4W5BA 1YK7A 2JQFR 2F1GA 2HD5A 1MHWA 2VFBA 4DMXA 1CQDA 4YYQA 3OISA 1GMYA 4QRXA 1PADA 1BGOA 1K3BB 2DCBA 1QXPA 3S3QA 4BS5A 2GHUA 4KLBA 3BCNA 1M6DA 2AS8A 2BDLA 3H8BA 3QT4A 1KFUL 3F75A 1W4TA 3P5UA 4YYRA 4N79A 1STFE 4PI3A 1X9YA 1PPPA 2PNSA 4I04A 3K9MA 2R9NA 1KXRA 3PDFA 2YJ9A 4QRGA 1SNKA 3GCBA 3IV2A 4WA6A 4I05A 1ICFA 3K24A 4AXLA 1AU0A 4C5PA 4YYUA 1F29A 4CZWA 3PBHA 1YVBA 3HWNA 4ZUXU 3V6EA 1F2CA 3N3GA 4DMYA 2DZZA 5A24A 1S4VA 1EWMA 3H8CA 2AUXA 1EWOA 3WXFA 1YK8A 4MSXA 1ME4A 2AU1A 5PADA 1MEMA 3BPFA 3D6SA 2XU5A 1AU3A 3LFYA 4MZOA 2P0RA 5F02A 2Y6EA 1W6FA 1PIPA 2P86A 3LTWA 5CHVA 2R9CA 1O0EA 4RY2A 2NQDB 3ZUAA 1NLJA 3PNRA 4N4ZA 2DCDA 1EF7A 3P5XA 4GUZA 1BP4A 2VHSA 1ZIVA 3KFQA 2DC7A 1AYVA 3KKUA 3MHHA 2HH5A 3IEJA 2E02A 1PBHA 2FQ9A 1KHPA 1CPJA 1PCIA 1EWLA 1ME3A 1AIMA 2G7YA 4BQVA 2JQGR 5J94A 3D9WA 3O0UA 1F2BA 3OF8A 1PPDA 3HHAA 5FPWA 6PADA 5JH3A 2Y5BA 1PPOA 3BPMA 3P5WA 3DF0A 3C9EA 3RVXA 2VHFA 4NV7A 5JA7A 5CVOB 3WXGA 3TNXA 3CH2X 4CDDB 4BGFA 3AI8A 3HD3A 1XKGA 2R9FA 1JQPA 2FUDA 2R6NA 2DC8A 3H7DA 4YVAA 3N3KA 3S3RA 4XUIA 1NB3A 1QOLA 2FO5A 3U8EA 1CV8A 2DC6A 1CS8A 1MDWA 4PP1A 1CVZA 2R9OA 1TL9A 4X6IA 1FH0A 5CHTA 3H6SA 3K8UA 2XU3A 1YT7A 2ACTA 3KWZA 4YYWA 2AYOA 1MS6A 1CJLA 3IOQA 2PADA 4HWYA 3MORA 1IWDA 3CBJA 4G54A 3MHSA 5K16A 2G8JA 1AU2A 4MZSA 2HXZA 1U9WA 2GFOA 3E1ZB 1EWPA 2AVWA 3ERVA 4QBBA 1PE6A 8PCHA 2E01A 4YYSA 1E2TA 1U9VA 1U9XA 3IHPA 2OZ2A 3V6CA 1A6RA 1MEGA 3RVVA 1BQIA 2FT2A 3OVZA 3NHEA 2DCAA 1CB5A 1AECA 4W4UA 3CBKA 1CTEA 4X6JA 3OVXA 3BC3A 4P6EA 2OP3A 3M99A 3MTNA 2B1MA 4Q8HA 2PBHA 4CDFB 2C0YA 1KFXL 1BY8A 1F2AA 2CB5A 1U5IA 2VFCA 1AU4A 4FIPA 1ZCMA 2G8EA 4BSQA 3BWKA 3F5VA 3QSDA 2AIMA 1U9QX 4I07A 2FRQA 3N4CA 1Y4HA 3PW3A 2IBIA 9PAPA 4AXMA 3OF9A 2DC9A 3CH3X 1KHQA 2DZYA 2XU1A 4PP2E 2DJGB 3WXEA 2HHNA 4Q8GA 1NB5A 2AUZA 2WBFX 3B79A 3KX1A 4YYVA 1W5RA 4B55A 3P5VA 2CIOA 2BSZA 2P7UA 1AYWA 4FK5A 2YJ8A 1QMYA 2FTDA 1GCBA 2DJFB 4CDCB 1YALA 1NL6A 3LXSA 4XR7A 2NQAA 4YV8A 4NV8A 3BOWA 2DCCA 2E03A 2PREA 4OELA 1TLOA 1NQCA 1NPZA 7PCKA 3I3TA 4BPVA 2FYEA 2IPPB 3H89A 1GX3A 3KWBX 1MIRA 5CVMA 3USVA 1DEUA 1DF0A 2OULA 1TU6A 1HUCB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CVN B;  1PXV A;  2AYN A;  4FJC A;  1GEC E;  2NQI A;  1VJV A;  2E00 A;  2FRA A;  5EGW A;  4K7C A;  4P6G A;  1THE A;  4OEM A;  2G6D A;  2XU4 A;  2YJB A;  1QDQ A;  2ARY A;  1SP4 B;  2R9M A;  2B1N A;  1GLO A;  2H7J A;  3QJ3 A;  3I06 A;  2NQG A;  4BS6 A;  1PPN A;  2F7D A;  5EF4 A;  2BDZ A;  2ATO A;  4N8W A;  4QH6 A;  1ATK A;  1AYU A;  2YJ2 A;  3IMA A;  3KW9 A;  1CSB B;  3RVW A;  3IUT A;  4CDE B;  3HHI A;  4X6H A;  4W5C A;  2YJC A;  1Y08 A;  3KSE A;  1VSN A;  1ITO A;  4PAD A;  1POP A;  2O6X A;  1Q6K A;  3O1G A;  4QRV A;  4W5B A;  1YK7 A;  2JQF R;  2F1G A;  2HD5 A;  1MHW A;  4DMX A;  1CQD A;  4YYQ A;  3OIS A;  1GMY A;  4QRX A;  1BGO A;  1K3B B;  1PAD A;  2DCB A;  1QXP A;  3S3Q A;  4BS5 A;  2GHU A;  4KLB A;  3BCN A;  1M6D A;  2AS8 A;  2BDL A;  3H8B A;  3QT4 A;  1KFU L;  3F75 A;  3P5U A;  4YYR A;  4N79 A;  1STF E;  4PI3 A;  1X9Y A;  1PPP A;  2PNS A;  4I04 A;  3K9M A;  2R9N A;  1KXR A;  3PDF A;  2YJ9 A;  4QRG A;  1SNK A;  3GCB A;  3IV2 A;  4WA6 A;  4I05 A;  1ICF A;  3K24 A;  4AXL A;  1AU0 A;  4YYU A;  1F29 A;  4CZW A;  3PBH A;  1YVB A;  3HWN A;  4ZUX U;  3V6E A;  1F2C A;  3N3G A;  4DMY A;  2DZZ A;  5A24 A;  1S4V A;  1EWM A;  3H8C A;  2AUX A;  1EWO A;  3WXF A;  1YK8 A;  4MSX A;  1ME4 A;  2AU1 A;  5PAD A;  1MEM A;  3BPF A;  3D6S A;  2XU5 A;  1AU3 A;  3LFY A;  4MZO A;  2P0R A;  5F02 A;  2Y6E A;  1PIP A;  2P86 A;  5CHV A;  2R9C A;  1O0E A;  4RY2 A;  2NQD B;  3ZUA A;  1NLJ A;  3PNR A;  4N4Z A;  2DCD A;  1EF7 A;  3P5X A;  1BP4 A;  2VHS A;  1ZIV A;  3KFQ A;  2DC7 A;  1AYV A;  3KKU A;  3MHH A;  2HH5 A;  3IEJ A;  2E02 A;  1PBH A;  2FQ9 A;  1KHP A;  1CPJ A;  1PCI A;  1EWL A;  1ME3 A;  1AIM A;  2G7Y A;  4BQV A;  2JQG R;  5J94 A;  3O0U A;  1F2B A;  3OF8 A;  1PPD A;  3HHA A;  5FPW A;  6PAD A;  5JH3 A;  2Y5B A;  1PPO A;  3BPM A;  3P5W A;  3DF0 A;  3C9E A;  3RVX A;  2VHF A;  5JA7 A;  5CVO B;  3WXG A;  3TNX A;  3CH2 X;  4CDD B;  3AI8 A;  3HD3 A;  1XKG A;  2R9F A;  1JQP A;  2FUD A;  2R6N A;  2DC8 A;  3H7D A;  4YVA A;  3N3K A;  3S3R A;  4XUI A;  1NB3 A;  1QOL A;  2FO5 A;  3U8E A;  1CV8 A;  2DC6 A;  1CS8 A;  1MDW A;  4PP1 A;  1CVZ A;  2R9O A;  1TL9 A;  4X6I A;  1FH0 A;  5CHT A;  3H6S A;  3K8U A;  2XU3 A;  1YT7 A;  2ACT A;  3KWZ A;  4YYW A;  2AYO A;  1MS6 A;  1CJL A;  3IOQ A;  2PAD A;  4HWY A;  3MOR A;  1IWD A;  3CBJ A;  4G54 A;  3MHS A;  5K16 A;  2G8J A;  1AU2 A;  4MZS A;  2HXZ A;  1U9W A;  2GFO A;  3E1Z B;  1EWP A;  2AVW A;  3ERV A;  4QBB A;  1PE6 A;  8PCH A;  2E01 A;  4YYS A;  1U9V A;  1U9X A;  3IHP A;  2OZ2 A;  3V6C A;  1A6R A;  1MEG A;  3RVV A;  1BQI A;  2FT2 A;  3OVZ A;  3NHE A;  2DCA A;  1CB5 A;  1AEC A;  4W4U A;  3CBK A;  1CTE A;  4X6J A;  3OVX A;  3BC3 A;  4P6E A;  2OP3 A;  3M99 A;  3MTN A;  2B1M A;  4Q8H A;  2PBH A;  4CDF B;  2C0Y A;  1KFX L;  1BY8 A;  1F2A A;  2CB5 A;  1U5I A;  1AU4 A;  4FIP A;  1ZCM A;  2G8E A;  4BSQ A;  3BWK A;  3F5V A;  3QSD A;  2AIM A;  1U9Q X;  4I07 A;  2FRQ A;  3N4C A;  1Y4H A;  3PW3 A;  2IBI A;  9PAP A;  4AXM A;  3OF9 A;  2DC9 A;  3CH3 X;  1KHQ A;  2DZY A;  2XU1 A;  4PP2 E;  2DJG B;  3WXE A;  2HHN A;  4Q8G A;  1NB5 A;  2AUZ A;  2WBF X;  3B79 A;  3KX1 A;  4YYV A;  3P5V A;  2CIO A;  2P7U A;  1AYW A;  4FK5 A;  2YJ8 A;  1QMY A;  2FTD A;  1GCB A;  2DJF B;  4CDC B;  1YAL A;  1NL6 A;  3LXS A;  4XR7 A;  2NQA A;  4YV8 A;  3BOW A;  2DCC A;  2E03 A;  2PRE A;  4OEL A;  1TLO A;  1NQC A;  1NPZ A;  7PCK A;  3I3T A;  4BPV A;  2FYE A;  2IPP B;  3H89 A;  3KWB X;  1MIR A;  5CVM A;  3USV A;  1DEU A;  1DF0 A;  2OUL A;  1TU6 A;  1HUC B; 
#chains in the Genus database with same CATH topology
 1UKF A;  5CVN B;  1PXV A;  4ZTB A;  2AYN A;  4FJC A;  3MP2 A;  3W31 A;  1GEC E;  2NQI A;  3PHU A;  1VJV A;  2E00 A;  2FRA A;  5EGW A;  4K7C A;  4P6G A;  1THE A;  4OEM A;  2G6D A;  2XU4 A;  2YJB A;  1QDQ A;  2ARY A;  1SP4 B;  2R9M A;  2B1N A;  1GLO A;  2UZJ A;  2H7J A;  3QJ3 A;  3I06 A;  2NQG A;  4BS6 A;  4XZX A;  1PPN A;  2F7D A;  5EF4 A;  2BDZ A;  2ATO A;  4N8W A;  3E9S A;  4QH6 A;  1ATK A;  1AYU A;  2YJ2 A;  3IMA A;  3KW9 A;  1CSB B;  3RVW A;  3IUT A;  4CDE B;  3HHI A;  4X6H A;  4W5C A;  2YJC A;  1Y08 A;  3KSE A;  1VSN A;  1ITO A;  4PAD A;  1POP A;  2O6X A;  1Q6K A;  3O1G A;  4QRV A;  4W5B A;  1YK7 A;  2JQF R;  2F1G A;  2HD5 A;  3PHW A;  1MHW A;  4DMX A;  1CQD A;  4YYQ A;  3OIS A;  1GMY A;  4QRX A;  1BGO A;  1K3B B;  1PAD A;  2DCB A;  1QXP A;  3S3Q A;  4BS5 A;  2GHU A;  4KLB A;  3BCN A;  1M6D A;  2AS8 A;  2BDL A;  3H8B A;  3QT4 A;  4GUA A;  1KFU L;  3F75 A;  3P5U A;  4YYR A;  3C0R A;  2DOS A;  4N79 A;  1STF E;  4PI3 A;  1X9Y A;  1PPP A;  2PNS A;  4R3D A;  4I04 A;  3K9M A;  2R9N A;  1KXR A;  3PDF A;  4M0W A;  2YJ9 A;  4QRG A;  4BOS A;  3O65 A;  1SNK A;  1DKI A;  3GCB A;  3PRM A;  5EZS A;  3IV2 A;  4WA6 A;  4I05 A;  4BOP A;  1ICF A;  3K24 A;  4AXL A;  1AU0 A;  4YYU A;  1F29 A;  4CZW A;  3PBH A;  1YVB A;  4A5U A;  3HWN A;  4ZUX U;  3V6E A;  1F2C A;  3N3G A;  4DMY A;  2DZZ A;  5A24 A;  1S4V A;  1EWM A;  3H8C A;  2AUX A;  1EWO A;  3MJ5 A;  3WXF A;  1YK8 A;  4MSX A;  1ME4 A;  2AU1 A;  5PAD A;  1MEM A;  3BPF A;  3D6S A;  2JTC A;  2XU5 A;  1AU3 A;  3LFY A;  2J7Q C;  4MZO A;  2P0R A;  5F02 A;  2Y6E A;  1PIP A;  2P86 A;  5CHV A;  2R9C A;  1O0E A;  4RY2 A;  2NQD B;  3MTV A;  3ZUA A;  1NLJ A;  5E6J A;  3PNR A;  4N4Z A;  3ZNH A;  2DCD A;  1EF7 A;  3PSE A;  3P5X A;  2AGA A;  1BP4 A;  2VHS A;  1ZIV A;  3KFQ A;  2DC7 A;  1AYV A;  3KKU A;  4RNA A;  3MHH A;  3PT2 A;  2HH5 A;  3TRK A;  3IEJ A;  2BU3 A;  2E02 A;  1PBH A;  2FQ9 A;  1KHP A;  1CPJ A;  1PCI A;  1EWL A;  1ME3 A;  1AIM A;  2G7Y A;  4BQV A;  2JQG R;  5J94 A;  2BTW B;  3O0U A;  1F2B A;  3OF8 A;  1PPD A;  3HHA A;  5FPW A;  6PAD A;  5JH3 A;  2Y5B A;  1PPO A;  3BPM A;  3P5W A;  2BTW A;  3DF0 A;  4OW0 A;  3C9E A;  3RVX A;  2VHF A;  5JA7 A;  4D8E A;  5CVO B;  3WXG A;  3TNX A;  3CH2 X;  4CDD B;  3AI8 A;  3HD3 A;  1XKG A;  2R9F A;  1JQP A;  2FUD A;  2R6N A;  4OVZ B;  2DC8 A;  3H7D A;  4YVA A;  3N3K A;  3S3R A;  4XUI A;  1NB3 A;  1QOL A;  2FO5 A;  3U8E A;  1CV8 A;  2DC6 A;  1CS8 A;  1MDW A;  2FE8 A;  4PP1 A;  1CVZ A;  2R9O A;  1TL9 A;  4X6I A;  3B21 A;  1FH0 A;  5CHT A;  3H6S A;  3PHX A;  3K8U A;  2XU3 A;  4OVZ A;  1YT7 A;  2ACT A;  3KWZ A;  4YYW A;  5JZE A;  2AYO A;  1MS6 A;  1CJL A;  3IOQ A;  2PAD A;  4HWY A;  3MOR A;  1IWD A;  3CBJ A;  1YZB A;  4G54 A;  3MHS A;  5K16 A;  2G8J A;  1AU2 A;  3IFU A;  4MZS A;  2HXZ A;  4HXD B;  3OQC A;  1U9W A;  2GFO A;  3E1Z B;  1EWP A;  2AVW A;  4P16 A;  3ERV A;  4QBB A;  1PE6 A;  8PCH A;  2E01 A;  4YYS A;  1U9V A;  2JRI A;  1U9X A;  3IHP A;  4IUM A;  2OZ2 A;  3V6C A;  4BOQ A;  1A6R A;  3BY4 A;  1MEG A;  3RVV A;  4MI7 A;  1BQI A;  2FT2 A;  3OVZ A;  3NHE A;  2DCA A;  3RNV A;  5KO3 A;  1CB5 A;  4RF1 A;  1AEC A;  4W4U A;  3CBK A;  1CTE A;  4X6J A;  3OVX A;  4BOU A;  4IP3 A;  3BC3 A;  4P6E A;  2OP3 A;  3M99 A;  3MTN A;  2B1M A;  3BB7 A;  4Q8H A;  2PBH A;  4CDF B;  2C0Y A;  3W30 A;  1KFX L;  1BY8 A;  1F2A A;  2CB5 A;  1U5I A;  1AU4 A;  4FIP A;  1ZCM A;  2G8E A;  4BSQ A;  3BWK A;  3F5V A;  3QSD A;  2AIM A;  1U9Q X;  4I07 A;  2FRQ A;  3N4C A;  1Y4H A;  3PW3 A;  2IBI A;  9PAP A;  4AXM A;  3OF9 A;  2DC9 A;  3CH3 X;  1KHQ A;  2J7Q A;  3PRP A;  2DZY A;  5EZQ A;  2XU1 A;  4PP2 E;  2DJG B;  4D8I A;  3WXE A;  2HHN A;  2HWK A;  4Q8G A;  1NB5 A;  2AUZ A;  2WBF X;  3B79 A;  3KX1 A;  4YYV A;  4MM3 B;  4RKX A;  3P5V A;  2CIO A;  3BBA A;  2P7U A;  1AYW A;  4FK5 A;  2YJ8 A;  1QMY A;  2FTD A;  1GCB A;  2DJF B;  4CDC B;  1YAL A;  1NL6 A;  3LXS A;  4XR7 A;  2NQA A;  4YV8 A;  4WUR A;  4BOZ A;  4PT5 A;  3BOW A;  2DCC A;  2E03 A;  2PRE A;  4RF0 A;  4D8B A;  1PVJ A;  4REZ A;  4OEL A;  1TLO A;  1NQC A;  1NPZ A;  7PCK A;  3I3T A;  4BPV A;  2FYE A;  2Z84 A;  3TMP A;  2IPP B;  3H89 A;  3KWB X;  1MIR A;  5CVM A;  3USV A;  1DEU A;  1DF0 A;  2OUL A;  1TU6 A;  1HUC B; 
#chains in the Genus database with same CATH homology
 5CVN B;  1PXV A;  2AYN A;  4FJC A;  1GEC E;  2NQI A;  1VJV A;  2E00 A;  2FRA A;  5EGW A;  4K7C A;  4P6G A;  1THE A;  4OEM A;  2G6D A;  2XU4 A;  2YJB A;  1QDQ A;  2ARY A;  1SP4 B;  2R9M A;  2B1N A;  1GLO A;  2H7J A;  3QJ3 A;  3I06 A;  2NQG A;  4BS6 A;  1PPN A;  2F7D A;  5EF4 A;  2BDZ A;  2ATO A;  4N8W A;  4QH6 A;  1ATK A;  1AYU A;  2YJ2 A;  3IMA A;  3KW9 A;  1CSB B;  3RVW A;  3IUT A;  4CDE B;  3HHI A;  4X6H A;  4W5C A;  2YJC A;  1Y08 A;  3KSE A;  1VSN A;  1ITO A;  4PAD A;  1POP A;  2O6X A;  1Q6K A;  3O1G A;  4QRV A;  4W5B A;  1YK7 A;  2JQF R;  2F1G A;  2HD5 A;  1MHW A;  2VFB A;  4DMX A;  1CQD A;  4YYQ A;  3OIS A;  1GMY A;  4QRX A;  1PAD A;  1BGO A;  1K3B B;  2DCB A;  1QXP A;  3S3Q A;  4BS5 A;  2GHU A;  4KLB A;  3BCN A;  1M6D A;  2AS8 A;  2BDL A;  3H8B A;  3QT4 A;  1KFU L;  3F75 A;  1W4T A;  3P5U A;  4YYR A;  4N79 A;  1STF E;  4PI3 A;  1X9Y A;  1PPP A;  2PNS A;  4I04 A;  3K9M A;  2R9N A;  1KXR A;  3PDF A;  2YJ9 A;  4QRG A;  1SNK A;  3GCB A;  3IV2 A;  4WA6 A;  4I05 A;  1ICF A;  3K24 A;  4AXL A;  1AU0 A;  4C5P A;  4YYU A;  1F29 A;  4CZW A;  3PBH A;  1YVB A;  3HWN A;  4ZUX U;  3V6E A;  1F2C A;  3N3G A;  4DMY A;  2DZZ A;  5A24 A;  1S4V A;  1EWM A;  3H8C A;  2AUX A;  1EWO A;  3WXF A;  1YK8 A;  4MSX A;  1ME4 A;  2AU1 A;  5PAD A;  1MEM A;  3BPF A;  3D6S A;  2XU5 A;  1AU3 A;  3LFY A;  4MZO A;  2P0R A;  5F02 A;  2Y6E A;  1W6F A;  1PIP A;  2P86 A;  3LTW A;  5CHV A;  2R9C A;  1O0E A;  4RY2 A;  2NQD B;  3ZUA A;  1NLJ A;  3PNR A;  4N4Z A;  2DCD A;  1EF7 A;  3P5X A;  4GUZ A;  1BP4 A;  2VHS A;  1ZIV A;  3KFQ A;  2DC7 A;  1AYV A;  3KKU A;  3MHH A;  2HH5 A;  3IEJ A;  2E02 A;  1PBH A;  2FQ9 A;  1KHP A;  1CPJ A;  1PCI A;  1EWL A;  1ME3 A;  1AIM A;  2G7Y A;  4BQV A;  2JQG R;  5J94 A;  3D9W A;  3O0U A;  1F2B A;  3OF8 A;  1PPD A;  3HHA A;  5FPW A;  6PAD A;  5JH3 A;  2Y5B A;  1PPO A;  3BPM A;  3P5W A;  3DF0 A;  3C9E A;  3RVX A;  2VHF A;  4NV7 A;  5JA7 A;  5CVO B;  3WXG A;  3TNX A;  3CH2 X;  4CDD B;  4BGF A;  3AI8 A;  3HD3 A;  1XKG A;  2R9F A;  1JQP A;  2FUD A;  2R6N A;  2DC8 A;  3H7D A;  4YVA A;  3N3K A;  3S3R A;  4XUI A;  1NB3 A;  1QOL A;  2FO5 A;  3U8E A;  1CV8 A;  2DC6 A;  1CS8 A;  1MDW A;  4PP1 A;  1CVZ A;  2R9O A;  1TL9 A;  4X6I A;  1FH0 A;  5CHT A;  3H6S A;  3K8U A;  2XU3 A;  1YT7 A;  2ACT A;  3KWZ A;  4YYW A;  2AYO A;  1MS6 A;  1CJL A;  3IOQ A;  2PAD A;  4HWY A;  3MOR A;  1IWD A;  3CBJ A;  4G54 A;  3MHS A;  5K16 A;  2G8J A;  1AU2 A;  4MZS A;  2HXZ A;  1U9W A;  2GFO A;  3E1Z B;  1EWP A;  2AVW A;  3ERV A;  4QBB A;  1PE6 A;  8PCH A;  2E01 A;  4YYS A;  1E2T A;  1U9V A;  1U9X A;  3IHP A;  2OZ2 A;  3V6C A;  1A6R A;  1MEG A;  3RVV A;  1BQI A;  2FT2 A;  3OVZ A;  3NHE A;  2DCA A;  1CB5 A;  1AEC A;  4W4U A;  3CBK A;  1CTE A;  4X6J A;  3OVX A;  3BC3 A;  4P6E A;  2OP3 A;  3M99 A;  3MTN A;  2B1M A;  4Q8H A;  2PBH A;  4CDF B;  2C0Y A;  1KFX L;  1BY8 A;  1F2A A;  2CB5 A;  1U5I A;  2VFC A;  1AU4 A;  4FIP A;  1ZCM A;  2G8E A;  4BSQ A;  3BWK A;  3F5V A;  3QSD A;  2AIM A;  1U9Q X;  4I07 A;  2FRQ A;  3N4C A;  1Y4H A;  3PW3 A;  2IBI A;  9PAP A;  4AXM A;  3OF9 A;  2DC9 A;  3CH3 X;  1KHQ A;  2DZY A;  2XU1 A;  4PP2 E;  2DJG B;  3WXE A;  2HHN A;  4Q8G A;  1NB5 A;  2AUZ A;  2WBF X;  3B79 A;  3KX1 A;  4YYV A;  1W5R A;  4B55 A;  3P5V A;  2CIO A;  2BSZ A;  2P7U A;  1AYW A;  4FK5 A;  2YJ8 A;  1QMY A;  2FTD A;  1GCB A;  2DJF B;  4CDC B;  1YAL A;  1NL6 A;  3LXS A;  4XR7 A;  2NQA A;  4YV8 A;  4NV8 A;  3BOW A;  2DCC A;  2E03 A;  2PRE A;  4OEL A;  1TLO A;  1NQC A;  1NPZ A;  7PCK A;  3I3T A;  4BPV A;  2FYE A;  2IPP B;  3H89 A;  1GX3 A;  3KWB X;  1MIR A;  5CVM A;  3USV A;  1DEU A;  1DF0 A;  2OUL A;  1TU6 A;  1HUC B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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