2YJBA

Cathepsin l with a nitrile inhibitor
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
220
structure length
220
Chain Sequence
APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Halogen Bonding at the Active Sites of Human Cathepsin L and Mek1 Kinase: Efficient Interactions in Different Environments.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords CATHEPSIN L1
total genus 70
structure length 220
sequence length 220
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2011-05-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2yjbA00
3N3KA 1PPDA 1PXVA 4QRGA 2VHSA 4X6IA 4OEMA 4I05A 2E00A 1U9VA 4N4ZA 4X6HA 3KWZA 2DC9A 2P7UA 1X9YA 3IHPA 1EF7A 1NB3A 1AU4A 3I06A 2YJ8A 4PP1A 3E1ZB 2HH5A 1FH0A 1CS8A 1F2CA 4Q8HA 4BS5A 1YVBA 1JQPA 5JH3A 1CPJA 4W4UA 1Q6KA 2AUXA 3OF9A 3H7DA 1SP4B 3P5VA 4QBBA 4CZWA 2CB5A 3I3TA 4RY2A 9PAPA 2DZZA 2R9OA 3BWKA 2OULA 1U9WA 3KSEA 1CSBB 1GCBA 1BQIA 2Y5BA 1VJVA 2R9NA 1ITOA 2XU1A 3B79A 4YV8A 1PIPA 2FUDA 2JQFR 2Y6EA 3D6SA 4P6GA 3CH2X 4I04A 1IWDA 2PREA 2YJBA 2DCAA 3O1GA 2DC7A 4YYSA 2AYNA 1AU2A 4DMXA 3OISA 2YJCA 4CDDB 1ZIVA 3H8BA 2F7DA 2DC8A 3BOWA 1MEMA 1CB5A 1STFE 1HUCB 1AYWA 1PPNA 2FO5A 4G54A 2G6DA 1AYVA 3BPMA 1AECA 4AXMA 4FK5A 4BPVA 3MHHA 6PADA 4OELA 2DJFB 1GECE 2PBHA 3K24A 2GFOA 2HHNA 1YK7A 1Y08A 2E01A 3IUTA 3BC3A 1PPPA 1U9XA 3C9EA 2E02A 2AIMA 5F02A 1CJLA 4W5BA 3IOQA 4W5CA 2DJGB 2R6NA 3H6SA 2FRQA 4QRVA 1AYUA 3CBKA 3ZUAA 5EF4A 1NB5A 1YK8A 2H7JA 4FJCA 3F5VA 4X6JA 1K3BB 3WXGA 2R9CA 5A24A 4XR7A 3WXEA 4BSQA 3HHIA 3P5XA 2R9MA 3OVZA 1ICFA 4YYUA 1BGOA 3N4CA 3HWNA 2BDLA 2VHFA 2B1NA 3K8UA 3MORA 2DC6A 4BS6A 4QRXA 3CH3X 1QDQA 2ARYA 1F29A 4FIPA 3USVA 4MSXA 8PCHA 7PCKA 1ZCMA 3IMAA 4KLBA 4Q8GA 1AU0A 4MZOA 4N8WA 4HWYA 1GMYA 2FQ9A 5FPWA 1Y4HA 2JQGR 1QXPA 1BP4A 1VSNA 1PCIA 2NQDB 3N3GA 2NQGA 2G7YA 3PNRA 1S4VA 1EWLA 1QOLA 5CVNB 2IPPB 1EWPA 4YYVA 3H8CA 2ATOA 2F1GA 3CBJA 3RVVA 1MS6A 1TU6A 1DEUA 1EWOA 5CHVA 2E03A 3GCBA 3TNXA 4YYWA 1POPA 5CVOB 5PADA 3OVXA 1KHPA 3HD3A 5K16A 2G8EA 2PNSA 1XKGA 2AUZA 4MZSA 1PBHA 1CQDA 3HHAA 3P5UA 4N79A 4AXLA 3OF8A 3O0UA 1AU3A 4I07A 1YALA 1A6RA 3F75A 4YVAA 2XU3A 2FT2A 2OZ2A 3WXFA 4CDFB 1CVZA 2G8JA 2NQAA 3KWBX 2FTDA 1M6DA 1SNKA 3MTNA 1TLOA 3V6EA 2PADA 2P86A 1NPZA 2XU4A 2AU1A 2DZYA 4QH6A 3H89A 1MIRA 2O6XA 2DCDA 3DF0A 2AVWA 1MEGA 4YYQA 1YT7A 5EGWA 3NHEA 1MDWA 4K7CA 1F2BA 4YYRA 3ERVA 3QSDA 1CV8A 1PADA 1EWMA 2YJ9A 2HD5A 3K9MA 4XUIA 1PPOA 1THEA 1NQCA 2WBFX 2GHUA 1PE6A 1ME4A 1AIMA 1BY8A 2IBIA 2BDZA 3BCNA 2R9FA 2AYOA 5JA7A 3AI8A 3RVXA 4CDCB 2HXZA 1DF0A 2NQIA 2FYEA 1GLOA 1QMYA 3P5WA 3RVWA 2ACTA 3KW9A 2FRAA 1F2AA 3MHSA 3PW3A 1MHWA 2OP3A 4PI3A 3IV2A 3LFYA 5J94A 3U8EA 3KX1A 1TL9A 3M99A 3S3RA 1CTEA 4ZUXU 1KHQA 2YJ2A 4PADA 4P6EA 2P0RA 3IEJA 4PP2E 2DCCA 3PDFA 1O0EA 3KFQA 1ME3A 1KXRA 3QT4A 2DCBA 1U9QX 2XU5A 1KFUL 1KFXL 4DMYA 1NLJA 3V6CA 3LXSA 1NL6A 1U5IA 3PBHA 4WA6A 5CVMA 4CDEB 4BQVA 2CIOA 3S3QA 5CHTA 3BPFA 2AS8A 1ATKA 2B1MA 3KKUA 3QJ3A 2C0YA
chains in the Genus database with same CATH superfamily
3N3KA 1PPDA 1PXVA 3E9SA 4QRGA 2VHSA 4X6IA 4OEMA 4I05A 2E00A 1U9VA 4N4ZA 4X6HA 3KWZA 2DC9A 2P7UA 1X9YA 3IHPA 1EF7A 1NB3A 1AU4A 3I06A 2YJ8A 4PP1A 3E1ZB 2HH5A 4D8IA 1FH0A 1CS8A 1F2CA 2UZJA 4Q8HA 4BS5A 1YVBA 1JQPA 5JH3A 2BTWA 1CPJA 4W4UA 4OVZA 4RNAA 5E6JA 1Q6KA 2AUXA 3OF9A 2AGAA 3B21A 3H7DA 1SP4B 3P5VA 4QBBA 4ZTBA 4CZWA 2CB5A 4BOPA 3BB7A 3I3TA 4RY2A 3BBAA 9PAPA 2DZZA 2R9OA 3BWKA 4HXDB 4RF0A 2OULA 1U9WA 3C0RA 3KSEA 1CSBB 1GCBA 1BQIA 2Y5BA 1VJVA 2R9NA 1ITOA 2XU1A 4REZA 3B79A 3PT2A 2J7QA 4YV8A 1PIPA 2FUDA 2JQFR 2Y6EA 3D6SA 4P6GA 3CH2X 4I04A 1IWDA 2PREA 2YJBA 2DCAA 3O1GA 2DC7A 4YYSA 1YZBA 2AYNA 1AU2A 4DMXA 3OISA 2YJCA 4CDDB 4OVZB 1ZIVA 3H8BA 3ZNHA 2F7DA 2DC8A 3BOWA 3MJ5A 1MEMA 1CB5A 1STFE 2JTCA 1AYWA 1PPNA 2FO5A 4G54A 2G6DA 1AYVA 3BPMA 1AECA 4AXMA 4FK5A 4BPVA 3MHHA 4WURA 4OELA 6PADA 2DJFB 1GECE 2PBHA 3K24A 2GFOA 2HHNA 1YK7A 1Y08A 2E01A 3IUTA 3BC3A 3PSEA 1PPPA 1U9XA 3C9EA 2E02A 4R3DA 2AIMA 5F02A 1CJLA 4W5BA 3IOQA 4W5CA 2DJGB 2R6NA 3H6SA 2FRQA 4QRVA 1AYUA 3CBKA 3ZUAA 3OQCA 5EF4A 1NB5A 1YK8A 2H7JA 4FJCA 3F5VA 5EZQA 4X6JA 1K3BB 3WXGA 2R9CA 5A24A 4XR7A 3WXEA 3PHXA 4BSQA 3HHIA 4BOQA 3P5XA 2R9MA 3OVZA 3PRMA 1ICFA 3O65A 4YYUA 4BOSA 1BGOA 3N4CA 3HWNA 2BDLA 2VHFA 2B1NA 3K8UA 2J7QC 3MORA 2DC6A 4BS6A 4QRXA 3CH3X 1QDQA 2ARYA 1F29A 4FIPA 3USVA 4MSXA 8PCHA 7PCKA 1ZCMA 3IMAA 4KLBA 4Q8GA 3RNVA 3IFUA 4RKXA 1AU0A 4MZOA 4N8WA 4HWYA 1GMYA 2FQ9A 5FPWA 1PVJA 1Y4HA 2JQGR 1QXPA 1BP4A 1VSNA 1PCIA 2NQDB 3N3GA 2NQGA 2G7YA 3PNRA 1S4VA 1EWLA 1QOLA 5CVNB 2IPPB 1EWPA 3W31A 2BTWB 4YYVA 3H8CA 2ATOA 4MI7A 2F1GA 3TMPA 3CBJA 3RVVA 1MS6A 1TU6A 4A5UA 1DEUA 1EWOA 5CHVA 2E03A 3GCBA 4BOZA 3TNXA 4YYWA 1POPA 5CVOB 4IUMA 5PADA 3OVXA 1KHPA 3HD3A 5K16A 3PHWA 4M0WA 2G8EA 2PNSA 1XKGA 2AUZA 4MZSA 1PBHA 1CQDA 5JZEA 3HHAA 3P5UA 4N79A 3MP2A 4AXLA 3OF8A 3O0UA 1AU3A 4I07A 1YALA 4IP3A 1A6RA 3F75A 4YVAA 4XZXA 2XU3A 2FT2A 2OZ2A 3WXFA 4CDFB 3QJ3A 1CVZA 2G8JA 2NQAA 3KWBX 4PT5A 2FTDA 4BOUA 1M6DA 1SNKA 3MTNA 1TLOA 3V6EA 2PADA 2P86A 1NPZA 2XU4A 4D8BA 2AU1A 2DZYA 4QH6A 3H89A 1MIRA 2O6XA 2DCDA 3DF0A 2AVWA 1MEGA 4YYQA 1YT7A 5EGWA 3NHEA 1MDWA 4K7CA 1F2BA 4YYRA 2BU3A 3ERVA 1CV8A 3QSDA 1PADA 2JRIA 5EZSA 1EWMA 1UKFA 2YJ9A 2HD5A 3K9MA 4XUIA 1PPOA 1THEA 1NQCA 3MTVA 3W30A 2WBFX 2GHUA 1PE6A 1ME4A 1AIMA 4RF1A 1BY8A 2IBIA 2BDZA 3BCNA 2Z84A 2R9FA 2AYOA 5JA7A 3AI8A 3RVXA 4GUAA 4CDCB 2HXZA 1DF0A 5KO3A 4MM3B 2NQIA 2FYEA 1GLOA 1QMYA 3PHUA 3P5WA 3RVWA 2ACTA 4OW0A 3KW9A 2FRAA 1F2AA 3MHSA 3PW3A 1MHWA 2FE8A 2OP3A 3PRPA 4PI3A 3IV2A 3TRKA 3LFYA 5J94A 3U8EA 3KX1A 1TL9A 3M99A 2HWKA 3S3RA 1CTEA 4ZUXU 1KHQA 2YJ2A 4PADA 2DOSA 4P6EA 4D8EA 2P0RA 3IEJA 4PP2E 2DCCA 3BY4A 3PDFA 1O0EA 3KFQA 1ME3A 4P16A 1DKIA 1KXRA 3QT4A 2DCBA 1U9QX 2XU5A 1KFUL 1KFXL 4DMYA 1NLJA 3V6CA 3LXSA 1NL6A 1U5IA 3PBHA 4WA6A 5CVMA 4CDEB 4BQVA 2CIOA 3S3QA 5CHTA 3BPFA 2AS8A 1ATKA 2B1MA 3KKUA 1HUCB 2C0YA
chains in the Genus database with same CATH topology
3N3KA 1PPDA 1PXVA 4QRGA 2VHSA 4X6IA 4OEMA 4I05A 2E00A 1U9VA 4N4ZA 4X6HA 3KWZA 2DC9A 2P7UA 1X9YA 3IHPA 1EF7A 1NB3A 1AU4A 3I06A 2YJ8A 4PP1A 3E1ZB 2HH5A 3D9WA 1FH0A 1CS8A 1F2CA 4Q8HA 4BS5A 1YVBA 1JQPA 5JH3A 1CPJA 4W4UA 1Q6KA 2AUXA 3OF9A 3H7DA 1SP4B 3P5VA 4QBBA 4CZWA 2CB5A 3I3TA 4RY2A 9PAPA 2DZZA 2R9OA 3BWKA 1E2TA 2OULA 2BSZA 1U9WA 3KSEA 1CSBB 1GCBA 1BQIA 2Y5BA 1VJVA 2R9NA 1ITOA 2XU1A 3B79A 4YV8A 1PIPA 1W5RA 2FUDA 2JQFR 2Y6EA 3D6SA 4P6GA 3CH2X 4I04A 1IWDA 4B55A 2VFBA 2PREA 2YJBA 2DCAA 3O1GA 2DC7A 4YYSA 2AYNA 1AU2A 4DMXA 3OISA 2YJCA 4CDDB 1W4TA 1ZIVA 3H8BA 2F7DA 2DC8A 3BOWA 1MEMA 1CB5A 1STFE 1HUCB 1AYWA 1PPNA 2FO5A 4G54A 2G6DA 1AYVA 3BPMA 1AECA 4AXMA 4FK5A 4BPVA 3MHHA 6PADA 4OELA 2DJFB 1GECE 2PBHA 3K24A 2GFOA 2HHNA 1YK7A 1Y08A 2E01A 3IUTA 3BC3A 1PPPA 1U9XA 3C9EA 2E02A 2AIMA 5F02A 2VFCA 1CJLA 4W5BA 3IOQA 4W5CA 2DJGB 2R6NA 3H6SA 2FRQA 4QRVA 1AYUA 3CBKA 3ZUAA 5EF4A 1NB5A 1YK8A 2H7JA 4FJCA 3F5VA 4X6JA 1K3BB 3WXGA 2R9CA 5A24A 4XR7A 3WXEA 3LTWA 4BSQA 3HHIA 3P5XA 2R9MA 3OVZA 1ICFA 4YYUA 1BGOA 3N4CA 3HWNA 2BDLA 2VHFA 2B1NA 3K8UA 3MORA 2DC6A 4C5PA 4BS6A 4QRXA 3CH3X 1QDQA 2ARYA 1F29A 4FIPA 3USVA 4MSXA 8PCHA 7PCKA 1ZCMA 3IMAA 4KLBA 4Q8GA 1AU0A 4MZOA 4NV8A 4N8WA 4HWYA 4BGFA 1GMYA 2FQ9A 5FPWA 1Y4HA 2JQGR 1QXPA 1BP4A 1VSNA 1PCIA 2NQDB 3N3GA 2NQGA 2G7YA 3PNRA 1S4VA 1EWLA 1W6FA 4GUZA 1QOLA 5CVNB 2IPPB 1EWPA 4YYVA 3H8CA 2ATOA 2F1GA 3CBJA 3RVVA 1MS6A 1TU6A 1DEUA 1EWOA 5CHVA 2E03A 3GCBA 3TNXA 4YYWA 1POPA 5CVOB 5PADA 3OVXA 1KHPA 3HD3A 5K16A 2G8EA 2PNSA 1XKGA 2AUZA 4MZSA 1PBHA 1CQDA 3HHAA 3P5UA 4N79A 4AXLA 3OF8A 3O0UA 1AU3A 4I07A 1YALA 1A6RA 3F75A 4YVAA 2XU3A 2FT2A 2OZ2A 3WXFA 4CDFB 1CVZA 2G8JA 2NQAA 4NV7A 3KWBX 2FTDA 1M6DA 1SNKA 3MTNA 1TLOA 3V6EA 2PADA 2P86A 1NPZA 2XU4A 2AU1A 2DZYA 4QH6A 3H89A 1MIRA 2O6XA 2DCDA 3DF0A 2AVWA 1MEGA 4YYQA 1YT7A 5EGWA 3NHEA 1MDWA 4K7CA 1F2BA 4YYRA 3ERVA 3QSDA 1CV8A 1PADA 1EWMA 2YJ9A 2HD5A 3K9MA 4XUIA 1PPOA 1THEA 1NQCA 2WBFX 2GHUA 1PE6A 1ME4A 1AIMA 1BY8A 2IBIA 2BDZA 3BCNA 2R9FA 2AYOA 5JA7A 3AI8A 3RVXA 4CDCB 2HXZA 1DF0A 2NQIA 2FYEA 1GLOA 1QMYA 3P5WA 3RVWA 2ACTA 3KW9A 2FRAA 1F2AA 3MHSA 3PW3A 1MHWA 2OP3A 1GX3A 4PI3A 3IV2A 3LFYA 5J94A 3U8EA 3KX1A 1TL9A 3M99A 3S3RA 1CTEA 4ZUXU 1KHQA 2YJ2A 4PADA 4P6EA 2P0RA 3IEJA 4PP2E 2DCCA 3PDFA 1O0EA 3KFQA 1ME3A 1KXRA 3QT4A 2DCBA 1U9QX 2XU5A 1KFUL 1KFXL 4DMYA 1NLJA 3V6CA 3LXSA 1NL6A 1U5IA 3PBHA 4WA6A 5CVMA 4CDEB 4BQVA 2CIOA 3S3QA 5CHTA 3BPFA 2AS8A 1ATKA 2B1MA 3KKUA 3QJ3A 2C0YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3N3K A;  1PPD A;  1PXV A;  4QRG A;  2VHS A;  4X6I A;  4OEM A;  4I05 A;  2E00 A;  1U9V A;  4N4Z A;  4X6H A;  3KWZ A;  2DC9 A;  2P7U A;  1X9Y A;  3IHP A;  1EF7 A;  1NB3 A;  1AU4 A;  3I06 A;  2YJ8 A;  4PP1 A;  3E1Z B;  2HH5 A;  1FH0 A;  1CS8 A;  1F2C A;  4Q8H A;  4BS5 A;  1YVB A;  1JQP A;  5JH3 A;  1CPJ A;  4W4U A;  1Q6K A;  2AUX A;  3OF9 A;  3H7D A;  1SP4 B;  3P5V A;  4QBB A;  4CZW A;  2CB5 A;  3I3T A;  4RY2 A;  9PAP A;  2DZZ A;  2R9O A;  3BWK A;  2OUL A;  1U9W A;  3KSE A;  1CSB B;  1GCB A;  1BQI A;  2Y5B A;  1VJV A;  2R9N A;  1ITO A;  2XU1 A;  3B79 A;  4YV8 A;  1PIP A;  2FUD A;  2JQF R;  2Y6E A;  3D6S A;  4P6G A;  3CH2 X;  4I04 A;  1IWD A;  2PRE A;  2YJB A;  2DCA A;  3O1G A;  2DC7 A;  4YYS A;  2AYN A;  1AU2 A;  4DMX A;  3OIS A;  2YJC A;  4CDD B;  1ZIV A;  3H8B A;  2F7D A;  2DC8 A;  3BOW A;  1MEM A;  1CB5 A;  1STF E;  1HUC B;  1AYW A;  1PPN A;  2FO5 A;  4G54 A;  2G6D A;  1AYV A;  3BPM A;  1AEC A;  4AXM A;  4FK5 A;  4BPV A;  3MHH A;  6PAD A;  4OEL A;  2DJF B;  1GEC E;  2PBH A;  3K24 A;  2GFO A;  2HHN A;  1YK7 A;  1Y08 A;  2E01 A;  3IUT A;  3BC3 A;  1PPP A;  1U9X A;  3C9E A;  2E02 A;  2AIM A;  5F02 A;  1CJL A;  4W5B A;  3IOQ A;  4W5C A;  2DJG B;  2R6N A;  3H6S A;  2FRQ A;  4QRV A;  1AYU A;  3CBK A;  3ZUA A;  5EF4 A;  1NB5 A;  1YK8 A;  2H7J A;  4FJC A;  3F5V A;  4X6J A;  1K3B B;  3WXG A;  2R9C A;  5A24 A;  4XR7 A;  3WXE A;  4BSQ A;  3HHI A;  3P5X A;  2R9M A;  3OVZ A;  1ICF A;  4YYU A;  1BGO A;  3N4C A;  3HWN A;  2BDL A;  2VHF A;  2B1N A;  3K8U A;  3MOR A;  2DC6 A;  4BS6 A;  4QRX A;  3CH3 X;  1QDQ A;  2ARY A;  1F29 A;  4FIP A;  3USV A;  4MSX A;  8PCH A;  7PCK A;  1ZCM A;  3IMA A;  4KLB A;  4Q8G A;  1AU0 A;  4MZO A;  4N8W A;  4HWY A;  1GMY A;  2FQ9 A;  5FPW A;  1Y4H A;  2JQG R;  1QXP A;  1BP4 A;  1VSN A;  1PCI A;  2NQD B;  3N3G A;  2NQG A;  2G7Y A;  3PNR A;  1S4V A;  1EWL A;  1QOL A;  5CVN B;  2IPP B;  1EWP A;  4YYV A;  3H8C A;  2ATO A;  2F1G A;  3CBJ A;  3RVV A;  1MS6 A;  1TU6 A;  1DEU A;  1EWO A;  5CHV A;  2E03 A;  3GCB A;  3TNX A;  4YYW A;  1POP A;  5CVO B;  5PAD A;  3OVX A;  1KHP A;  3HD3 A;  5K16 A;  2G8E A;  2PNS A;  1XKG A;  2AUZ A;  4MZS A;  1PBH A;  1CQD A;  3HHA A;  3P5U A;  4N79 A;  4AXL A;  3OF8 A;  3O0U A;  1AU3 A;  4I07 A;  1YAL A;  1A6R A;  3F75 A;  4YVA A;  2XU3 A;  2FT2 A;  2OZ2 A;  3WXF A;  4CDF B;  1CVZ A;  2G8J A;  2NQA A;  3KWB X;  2FTD A;  1M6D A;  1SNK A;  3MTN A;  1TLO A;  3V6E A;  2PAD A;  2P86 A;  1NPZ A;  2XU4 A;  2AU1 A;  2DZY A;  4QH6 A;  3H89 A;  1MIR A;  2O6X A;  2DCD A;  3DF0 A;  2AVW A;  1MEG A;  4YYQ A;  1YT7 A;  5EGW A;  3NHE A;  1MDW A;  4K7C A;  1F2B A;  4YYR A;  3ERV A;  3QSD A;  1CV8 A;  1PAD A;  1EWM A;  2YJ9 A;  2HD5 A;  3K9M A;  4XUI A;  1PPO A;  1THE A;  1NQC A;  2WBF X;  2GHU A;  1PE6 A;  1ME4 A;  1AIM A;  1BY8 A;  2IBI A;  2BDZ A;  3BCN A;  2R9F A;  2AYO A;  5JA7 A;  3AI8 A;  3RVX A;  4CDC B;  2HXZ A;  1DF0 A;  2NQI A;  2FYE A;  1GLO A;  1QMY A;  3P5W A;  3RVW A;  2ACT A;  3KW9 A;  2FRA A;  1F2A A;  3MHS A;  3PW3 A;  1MHW A;  2OP3 A;  4PI3 A;  3IV2 A;  3LFY A;  5J94 A;  3U8E A;  3KX1 A;  1TL9 A;  3M99 A;  3S3R A;  1CTE A;  4ZUX U;  1KHQ A;  2YJ2 A;  4PAD A;  4P6E A;  2P0R A;  3IEJ A;  4PP2 E;  2DCC A;  3PDF A;  1O0E A;  3KFQ A;  1ME3 A;  1KXR A;  3QT4 A;  2DCB A;  1U9Q X;  2XU5 A;  1KFU L;  1KFX L;  4DMY A;  1NLJ A;  3V6C A;  3LXS A;  1NL6 A;  1U5I A;  3PBH A;  4WA6 A;  5CVM A;  4CDE B;  4BQV A;  2CIO A;  3S3Q A;  5CHT A;  3BPF A;  2AS8 A;  1ATK A;  2B1M A;  3KKU A;  3QJ3 A;  2C0Y A; 
#chains in the Genus database with same CATH topology
 3N3K A;  1PPD A;  1PXV A;  3E9S A;  4QRG A;  2VHS A;  4X6I A;  4OEM A;  4I05 A;  2E00 A;  1U9V A;  4N4Z A;  4X6H A;  3KWZ A;  2DC9 A;  2P7U A;  1X9Y A;  3IHP A;  1EF7 A;  1NB3 A;  1AU4 A;  3I06 A;  2YJ8 A;  4PP1 A;  3E1Z B;  2HH5 A;  4D8I A;  1FH0 A;  1CS8 A;  1F2C A;  2UZJ A;  4Q8H A;  4BS5 A;  1YVB A;  1JQP A;  5JH3 A;  2BTW A;  1CPJ A;  4W4U A;  4OVZ A;  4RNA A;  5E6J A;  1Q6K A;  2AUX A;  3OF9 A;  2AGA A;  3B21 A;  3H7D A;  1SP4 B;  3P5V A;  4QBB A;  4ZTB A;  4CZW A;  2CB5 A;  4BOP A;  3BB7 A;  3I3T A;  4RY2 A;  3BBA A;  9PAP A;  2DZZ A;  2R9O A;  3BWK A;  4HXD B;  4RF0 A;  2OUL A;  1U9W A;  3C0R A;  3KSE A;  1CSB B;  1GCB A;  1BQI A;  2Y5B A;  1VJV A;  2R9N A;  1ITO A;  2XU1 A;  4REZ A;  3B79 A;  3PT2 A;  2J7Q A;  4YV8 A;  1PIP A;  2FUD A;  2JQF R;  2Y6E A;  3D6S A;  4P6G A;  3CH2 X;  4I04 A;  1IWD A;  2PRE A;  2YJB A;  2DCA A;  3O1G A;  2DC7 A;  4YYS A;  1YZB A;  2AYN A;  1AU2 A;  4DMX A;  3OIS A;  2YJC A;  4CDD B;  4OVZ B;  1ZIV A;  3H8B A;  3ZNH A;  2F7D A;  2DC8 A;  3BOW A;  3MJ5 A;  1MEM A;  1CB5 A;  1STF E;  2JTC A;  1AYW A;  1PPN A;  2FO5 A;  4G54 A;  2G6D A;  1AYV A;  3BPM A;  1AEC A;  4AXM A;  4FK5 A;  4BPV A;  3MHH A;  4WUR A;  4OEL A;  6PAD A;  2DJF B;  1GEC E;  2PBH A;  3K24 A;  2GFO A;  2HHN A;  1YK7 A;  1Y08 A;  2E01 A;  3IUT A;  3BC3 A;  3PSE A;  1PPP A;  1U9X A;  3C9E A;  2E02 A;  4R3D A;  2AIM A;  5F02 A;  1CJL A;  4W5B A;  3IOQ A;  4W5C A;  2DJG B;  2R6N A;  3H6S A;  2FRQ A;  4QRV A;  1AYU A;  3CBK A;  3ZUA A;  3OQC A;  5EF4 A;  1NB5 A;  1YK8 A;  2H7J A;  4FJC A;  3F5V A;  5EZQ A;  4X6J A;  1K3B B;  3WXG A;  2R9C A;  5A24 A;  4XR7 A;  3WXE A;  3PHX A;  4BSQ A;  3HHI A;  4BOQ A;  3P5X A;  2R9M A;  3OVZ A;  3PRM A;  1ICF A;  3O65 A;  4YYU A;  4BOS A;  1BGO A;  3N4C A;  3HWN A;  2BDL A;  2VHF A;  2B1N A;  3K8U A;  2J7Q C;  3MOR A;  2DC6 A;  4BS6 A;  4QRX A;  3CH3 X;  1QDQ A;  2ARY A;  1F29 A;  4FIP A;  3USV A;  4MSX A;  8PCH A;  7PCK A;  1ZCM A;  3IMA A;  4KLB A;  4Q8G A;  3RNV A;  3IFU A;  4RKX A;  1AU0 A;  4MZO A;  4N8W A;  4HWY A;  1GMY A;  2FQ9 A;  5FPW A;  1PVJ A;  1Y4H A;  2JQG R;  1QXP A;  1BP4 A;  1VSN A;  1PCI A;  2NQD B;  3N3G A;  2NQG A;  2G7Y A;  3PNR A;  1S4V A;  1EWL A;  1QOL A;  5CVN B;  2IPP B;  1EWP A;  3W31 A;  2BTW B;  4YYV A;  3H8C A;  2ATO A;  4MI7 A;  2F1G A;  3TMP A;  3CBJ A;  3RVV A;  1MS6 A;  1TU6 A;  4A5U A;  1DEU A;  1EWO A;  5CHV A;  2E03 A;  3GCB A;  4BOZ A;  3TNX A;  4YYW A;  1POP A;  5CVO B;  4IUM A;  5PAD A;  3OVX A;  1KHP A;  3HD3 A;  5K16 A;  3PHW A;  4M0W A;  2G8E A;  2PNS A;  1XKG A;  2AUZ A;  4MZS A;  1PBH A;  1CQD A;  5JZE A;  3HHA A;  3P5U A;  4N79 A;  3MP2 A;  4AXL A;  3OF8 A;  3O0U A;  1AU3 A;  4I07 A;  1YAL A;  4IP3 A;  1A6R A;  3F75 A;  4YVA A;  4XZX A;  2XU3 A;  2FT2 A;  2OZ2 A;  3WXF A;  4CDF B;  3QJ3 A;  1CVZ A;  2G8J A;  2NQA A;  3KWB X;  4PT5 A;  2FTD A;  4BOU A;  1M6D A;  1SNK A;  3MTN A;  1TLO A;  3V6E A;  2PAD A;  2P86 A;  1NPZ A;  2XU4 A;  4D8B A;  2AU1 A;  2DZY A;  4QH6 A;  3H89 A;  1MIR A;  2O6X A;  2DCD A;  3DF0 A;  2AVW A;  1MEG A;  4YYQ A;  1YT7 A;  5EGW A;  3NHE A;  1MDW A;  4K7C A;  1F2B A;  4YYR A;  2BU3 A;  3ERV A;  1CV8 A;  3QSD A;  1PAD A;  2JRI A;  5EZS A;  1EWM A;  1UKF A;  2YJ9 A;  2HD5 A;  3K9M A;  4XUI A;  1PPO A;  1THE A;  1NQC A;  3MTV A;  3W30 A;  2WBF X;  2GHU A;  1PE6 A;  1ME4 A;  1AIM A;  4RF1 A;  1BY8 A;  2IBI A;  2BDZ A;  3BCN A;  2Z84 A;  2R9F A;  2AYO A;  5JA7 A;  3AI8 A;  3RVX A;  4GUA A;  4CDC B;  2HXZ A;  1DF0 A;  5KO3 A;  4MM3 B;  2NQI A;  2FYE A;  1GLO A;  1QMY A;  3PHU A;  3P5W A;  3RVW A;  2ACT A;  4OW0 A;  3KW9 A;  2FRA A;  1F2A A;  3MHS A;  3PW3 A;  1MHW A;  2FE8 A;  2OP3 A;  3PRP A;  4PI3 A;  3IV2 A;  3TRK A;  3LFY A;  5J94 A;  3U8E A;  3KX1 A;  1TL9 A;  3M99 A;  2HWK A;  3S3R A;  1CTE A;  4ZUX U;  1KHQ A;  2YJ2 A;  4PAD A;  2DOS A;  4P6E A;  4D8E A;  2P0R A;  3IEJ A;  4PP2 E;  2DCC A;  3BY4 A;  3PDF A;  1O0E A;  3KFQ A;  1ME3 A;  4P16 A;  1DKI A;  1KXR A;  3QT4 A;  2DCB A;  1U9Q X;  2XU5 A;  1KFU L;  1KFX L;  4DMY A;  1NLJ A;  3V6C A;  3LXS A;  1NL6 A;  1U5I A;  3PBH A;  4WA6 A;  5CVM A;  4CDE B;  4BQV A;  2CIO A;  3S3Q A;  5CHT A;  3BPF A;  2AS8 A;  1ATK A;  2B1M A;  3KKU A;  1HUC B;  2C0Y A; 
#chains in the Genus database with same CATH homology
 3N3K A;  1PPD A;  1PXV A;  4QRG A;  2VHS A;  4X6I A;  4OEM A;  4I05 A;  2E00 A;  1U9V A;  4N4Z A;  4X6H A;  3KWZ A;  2DC9 A;  2P7U A;  1X9Y A;  3IHP A;  1EF7 A;  1NB3 A;  1AU4 A;  3I06 A;  2YJ8 A;  4PP1 A;  3E1Z B;  2HH5 A;  3D9W A;  1FH0 A;  1CS8 A;  1F2C A;  4Q8H A;  4BS5 A;  1YVB A;  1JQP A;  5JH3 A;  1CPJ A;  4W4U A;  1Q6K A;  2AUX A;  3OF9 A;  3H7D A;  1SP4 B;  3P5V A;  4QBB A;  4CZW A;  2CB5 A;  3I3T A;  4RY2 A;  9PAP A;  2DZZ A;  2R9O A;  3BWK A;  1E2T A;  2OUL A;  2BSZ A;  1U9W A;  3KSE A;  1CSB B;  1GCB A;  1BQI A;  2Y5B A;  1VJV A;  2R9N A;  1ITO A;  2XU1 A;  3B79 A;  4YV8 A;  1PIP A;  1W5R A;  2FUD A;  2JQF R;  2Y6E A;  3D6S A;  4P6G A;  3CH2 X;  4I04 A;  1IWD A;  4B55 A;  2VFB A;  2PRE A;  2YJB A;  2DCA A;  3O1G A;  2DC7 A;  4YYS A;  2AYN A;  1AU2 A;  4DMX A;  3OIS A;  2YJC A;  4CDD B;  1W4T A;  1ZIV A;  3H8B A;  2F7D A;  2DC8 A;  3BOW A;  1MEM A;  1CB5 A;  1STF E;  1HUC B;  1AYW A;  1PPN A;  2FO5 A;  4G54 A;  2G6D A;  1AYV A;  3BPM A;  1AEC A;  4AXM A;  4FK5 A;  4BPV A;  3MHH A;  6PAD A;  4OEL A;  2DJF B;  1GEC E;  2PBH A;  3K24 A;  2GFO A;  2HHN A;  1YK7 A;  1Y08 A;  2E01 A;  3IUT A;  3BC3 A;  1PPP A;  1U9X A;  3C9E A;  2E02 A;  2AIM A;  5F02 A;  2VFC A;  1CJL A;  4W5B A;  3IOQ A;  4W5C A;  2DJG B;  2R6N A;  3H6S A;  2FRQ A;  4QRV A;  1AYU A;  3CBK A;  3ZUA A;  5EF4 A;  1NB5 A;  1YK8 A;  2H7J A;  4FJC A;  3F5V A;  4X6J A;  1K3B B;  3WXG A;  2R9C A;  5A24 A;  4XR7 A;  3WXE A;  3LTW A;  4BSQ A;  3HHI A;  3P5X A;  2R9M A;  3OVZ A;  1ICF A;  4YYU A;  1BGO A;  3N4C A;  3HWN A;  2BDL A;  2VHF A;  2B1N A;  3K8U A;  3MOR A;  2DC6 A;  4C5P A;  4BS6 A;  4QRX A;  3CH3 X;  1QDQ A;  2ARY A;  1F29 A;  4FIP A;  3USV A;  4MSX A;  8PCH A;  7PCK A;  1ZCM A;  3IMA A;  4KLB A;  4Q8G A;  1AU0 A;  4MZO A;  4NV8 A;  4N8W A;  4HWY A;  4BGF A;  1GMY A;  2FQ9 A;  5FPW A;  1Y4H A;  2JQG R;  1QXP A;  1BP4 A;  1VSN A;  1PCI A;  2NQD B;  3N3G A;  2NQG A;  2G7Y A;  3PNR A;  1S4V A;  1EWL A;  1W6F A;  4GUZ A;  1QOL A;  5CVN B;  2IPP B;  1EWP A;  4YYV A;  3H8C A;  2ATO A;  2F1G A;  3CBJ A;  3RVV A;  1MS6 A;  1TU6 A;  1DEU A;  1EWO A;  5CHV A;  2E03 A;  3GCB A;  3TNX A;  4YYW A;  1POP A;  5CVO B;  5PAD A;  3OVX A;  1KHP A;  3HD3 A;  5K16 A;  2G8E A;  2PNS A;  1XKG A;  2AUZ A;  4MZS A;  1PBH A;  1CQD A;  3HHA A;  3P5U A;  4N79 A;  4AXL A;  3OF8 A;  3O0U A;  1AU3 A;  4I07 A;  1YAL A;  1A6R A;  3F75 A;  4YVA A;  2XU3 A;  2FT2 A;  2OZ2 A;  3WXF A;  4CDF B;  1CVZ A;  2G8J A;  2NQA A;  4NV7 A;  3KWB X;  2FTD A;  1M6D A;  1SNK A;  3MTN A;  1TLO A;  3V6E A;  2PAD A;  2P86 A;  1NPZ A;  2XU4 A;  2AU1 A;  2DZY A;  4QH6 A;  3H89 A;  1MIR A;  2O6X A;  2DCD A;  3DF0 A;  2AVW A;  1MEG A;  4YYQ A;  1YT7 A;  5EGW A;  3NHE A;  1MDW A;  4K7C A;  1F2B A;  4YYR A;  3ERV A;  3QSD A;  1CV8 A;  1PAD A;  1EWM A;  2YJ9 A;  2HD5 A;  3K9M A;  4XUI A;  1PPO A;  1THE A;  1NQC A;  2WBF X;  2GHU A;  1PE6 A;  1ME4 A;  1AIM A;  1BY8 A;  2IBI A;  2BDZ A;  3BCN A;  2R9F A;  2AYO A;  5JA7 A;  3AI8 A;  3RVX A;  4CDC B;  2HXZ A;  1DF0 A;  2NQI A;  2FYE A;  1GLO A;  1QMY A;  3P5W A;  3RVW A;  2ACT A;  3KW9 A;  2FRA A;  1F2A A;  3MHS A;  3PW3 A;  1MHW A;  2OP3 A;  1GX3 A;  4PI3 A;  3IV2 A;  3LFY A;  5J94 A;  3U8E A;  3KX1 A;  1TL9 A;  3M99 A;  3S3R A;  1CTE A;  4ZUX U;  1KHQ A;  2YJ2 A;  4PAD A;  4P6E A;  2P0R A;  3IEJ A;  4PP2 E;  2DCC A;  3PDF A;  1O0E A;  3KFQ A;  1ME3 A;  1KXR A;  3QT4 A;  2DCB A;  1U9Q X;  2XU5 A;  1KFU L;  1KFX L;  4DMY A;  1NLJ A;  3V6C A;  3LXS A;  1NL6 A;  1U5I A;  3PBH A;  4WA6 A;  5CVM A;  4CDE B;  4BQV A;  2CIO A;  3S3Q A;  5CHT A;  3BPF A;  2AS8 A;  1ATK A;  2B1M A;  3KKU A;  3QJ3 A;  2C0Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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