2YJBA

Cathepsin l with a nitrile inhibitor
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
220
structure length
220
Chain Sequence
APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords CATHEPSIN L1
publication title Halogen Bonding at the Active Sites of Human Cathepsin L and Mek1 Kinase: Efficient Interactions in Different Environments.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 70
structure length 220
sequence length 220
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2011-05-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2yjbA00
3F5VA 3H8BA 1AU2A 1MS6A 1ME4A 4YVAA 3PDFA 5A24A 2IBIA 3TNXA 1PBHA 2P7UA 4RY2A 1F2CA 2G8EA 3P5WA 2R9NA 3MTNA 2H7JA 4DMXA 4N8WA 3N3GA 1M6DA 4PP2E 1DEUA 4W5BA 3MORA 3BPFA 4P6GA 2XU1A 3KWZA 4QRXA 4PI3A 1U9VA 3IOQA 3K24A 3MHHA 1MDWA 2PBHA 3WXGA 2DZYA 2GFOA 4BS5A 4KLBA 3M99A 4CDCB 3P5UA 1PPPA 1Y08A 2XU4A 4MSXA 2G8JA 4DMYA 4X6HA 3DF0A 3O1GA 2AUZA 2DCAA 3IEJA 2AVWA 1CVZA 1GMYA 2DCBA 4QBBA 3RVXA 5FPWA 1MEMA 2B1MA 3PNRA 4AXMA 3ZUAA 4HWYA 2XU5A 1ITOA 3H7DA 1TL9A 5EGWA 2R9FA 1BP4A 1BGOA 4QRVA 5PADA 3V6CA 1CPJA 4YYQA 3E1ZB 1KXRA 1U9QX 4K7CA 1AIMA 6PADA 2JQGR 1STFE 4G54A 4N79A 1VSNA 2DC6A 2HD5A 1ZIVA 1EF7A 1KHPA 2E00A 2PREA 1O0EA 4I05A 4N4ZA 8PCHA 4I04A 2DC8A 4BSQA 4PP1A 3P5VA 2XU3A 3O0UA 1U5IA 4CDDB 2OULA 1YK7A 1THEA 2G7YA 3P5XA 4PADA 2C0YA 1NQCA 2DJGB 2AU1A 2DCDA 2DJFB 3CBJA 3WXEA 2OZ2A 2BDLA 3BCNA 2DC7A 1CSBB 1XKGA 2CB5A 2PADA 3LFYA 5JH3A 2AUXA 4WA6A 2F7DA 1F2BA 4I07A 3KKUA 4QH6A 1TLOA 3KW9A 1CV8A 2O6XA 3I06A 3U8EA 3HWNA 4QRGA 2HXZA 1AYWA 1A6RA 2ACTA 2FO5A 1Y4HA 2Y6EA 2NQAA 3H8CA 1PCIA 1KHQA 2YJ9A 3HHAA 2R6NA 3K8UA 3OF8A 1K3BB 1AU3A 4YYVA 4YYSA 4BQVA 2R9OA 1EWLA 3AI8A 4CDFB 2HHNA 2OP3A 3PW3A 1YALA 7PCKA 1MEGA 3USVA 4Q8GA 4ZUXU 3NHEA 3H89A 2E03A 3MHSA 1BQIA 1PPOA 1PXVA 1POPA 2FRAA 4YYWA 1VJVA 1YVBA 1F29A 3K9MA 1MIRA 1CB5A 1EWOA 5EF4A 2IPPB 3CBKA 5CHVA 2NQDB 2YJ8A 1QXPA 3OVXA 3B79A 2AS8A 4FIPA 2DC9A 2DZZA 2FTDA 5K16A 3WXFA 3RVWA 1CJLA 1ATKA 4X6IA 3C9EA 3GCBA 1NB5A 1KFUL 2VHFA 2NQIA 4FJCA 1CTEA 3IV2A 4YYRA 1GECE 5CVNB 3KSEA 4P6EA 3OVZA 2AIMA 2R9MA 1GCBA 1PIPA 1TU6A 1AU0A 3QJ3A 3ERVA 2FYEA 4YYUA 4MZSA 9PAPA 1ME3A 4CZWA 2P86A 4W5CA 3BC3A 2CIOA 2PNSA 2G6DA 1SNKA 4XR7A 4MZOA 1QDQA 1BY8A 3QSDA 4CDEB 2ATOA 3KFQA 2P0RA 2NQGA 4Q8HA 1YK8A 1EWMA 1NLJA 1YT7A 2AYOA 1Q6KA 2Y5BA 5F02A 1PADA 1ICFA 2B1NA 3RVVA 3I3TA 1KFXL 3N3KA 3KX1A 4W4UA 5J94A 3H6SA 2E01A 1NL6A 2VHSA 1JQPA 3BWKA 1FH0A 3HD3A 2WBFX 3OF9A 3PBHA 1EWPA 1SP4B 1U9XA 3S3QA 2YJBA 2E02A 1HUCB 5CVMA 1PE6A 2FT2A 3KWBX 4YV8A 3D6SA 4BS6A 1ZCMA 1F2AA 2FRQA 2ARYA 1X9YA 1NPZA 2HH5A 4OELA 3LXSA 4BPVA 3HHIA 1DF0A 3F75A 3CH3X 1CS8A 4X6JA 2FUDA 5CHTA 3CH2X 1AU4A 1IWDA 3OISA 1U9WA 4XUIA 3IMAA 3QT4A 3S3RA 1MHWA 1QMYA 5JA7A 3V6EA 2BDZA 2JQFR 5CVOB 1PPNA 1S4VA 3N4CA 1AECA 2F1GA 1QOLA 3IHPA 2R9CA 1GLOA 1NB3A 4AXLA 4FK5A 3IUTA 2GHUA 3BPMA 2AYNA 1CQDA 2YJCA 1AYUA 1AYVA 1PPDA 2DCCA 2FQ9A 4OEMA 2YJ2A 3BOWA
chains in the Genus database with same CATH superfamily
3F5VA 3H8BA 4OW0A 1AU2A 1MS6A 1ME4A 4YVAA 3W31A 3PDFA 5A24A 2IBIA 3BBAA 3TNXA 1PBHA 2BU3A 2P7UA 1F2CA 4RY2A 2G8EA 3C0RA 3P5WA 2BTWB 2R9NA 3MTNA 2H7JA 4DMXA 4N8WA 3N3GA 1M6DA 4PP2E 1DEUA 4W5BA 3MORA 2HWKA 3BPFA 4P6GA 4R3DA 4WURA 2XU1A 3PRPA 3KWZA 3PRMA 4QRXA 4PI3A 1U9VA 3IOQA 4RKXA 3K24A 3MHHA 4D8BA 1MDWA 2PBHA 3WXGA 2FE8A 2DZYA 2GFOA 4BS5A 4KLBA 3M99A 4CDCB 3P5UA 1PPPA 1Y08A 1UKFA 2XU4A 4MSXA 2G8JA 5KO3A 4DMYA 4X6HA 3DF0A 3MP2A 3O1GA 2AUZA 2DCAA 3IEJA 2AVWA 1CVZA 1GMYA 2DCBA 4QBBA 3RVXA 5FPWA 1MEMA 2B1MA 3PNRA 4AXMA 3PSEA 4REZA 3ZUAA 4GUAA 4HWYA 2XU5A 1ITOA 3H7DA 4HXDB 2J7QA 1TL9A 5EGWA 2R9FA 1BP4A 1BGOA 4QRVA 5PADA 3V6CA 1CPJA 4YYQA 3E1ZB 1KXRA 1U9QX 4K7CA 1AIMA 6PADA 2JQGR 1STFE 4G54A 4N79A 1VSNA 2DC6A 2HD5A 1ZIVA 4BOUA 1EF7A 1KHPA 2E00A 2PREA 1O0EA 4I05A 4N4ZA 8PCHA 4I04A 3B21A 4RF1A 2DC8A 2JRIA 4BSQA 2DOSA 4PP1A 3P5VA 2XU3A 3O0UA 1U5IA 4CDDB 2OULA 1YK7A 1THEA 4BOZA 2G7YA 3P5XA 4PADA 2C0YA 1NQCA 4MM3B 2DJGB 4XZXA 2AU1A 2DCDA 2DJFB 3CBJA 3WXEA 2J7QC 2OZ2A 2BDLA 3TRKA 3BCNA 5EZQA 2DC7A 1CSBB 1XKGA 2CB5A 2PADA 3LFYA 5JH3A 2AUXA 4WA6A 2F7DA 1F2BA 3IFUA 2BTWA 4I07A 3KKUA 4QH6A 1TLOA 3KW9A 2AGAA 1CV8A 2O6XA 3I06A 3U8EA 3HWNA 4QRGA 3O65A 2HXZA 1AYWA 1A6RA 2ACTA 2FO5A 1Y4HA 2Y6EA 2NQAA 3H8CA 1PCIA 1KHQA 2YJ9A 3HHAA 2R6NA 4PT5A 4RNAA 5E6JA 3K8UA 3OF8A 1K3BB 1AU3A 4YYVA 4YYSA 4BQVA 2R9OA 1EWLA 3AI8A 4CDFB 2HHNA 2OP3A 3PW3A 1YALA 4D8IA 7PCKA 1MEGA 3USVA 4Q8GA 4ZUXU 3NHEA 3H89A 2E03A 3MHSA 1BQIA 1PPOA 1PXVA 1POPA 2FRAA 4YYWA 1VJVA 1YVBA 1F29A 3K9MA 4A5UA 1MIRA 1CB5A 1EWOA 5EF4A 2IPPB 3BY4A 3CBKA 5CHVA 2NQDB 2YJ8A 1QXPA 3OVXA 3B79A 2AS8A 4FIPA 2DC9A 2DZZA 2FTDA 5K16A 3WXFA 5EZSA 4BOSA 3RVWA 1CJLA 1ATKA 4X6IA 2JTCA 3C9EA 3GCBA 1NB5A 1YZBA 1KFUL 2VHFA 2NQIA 4FJCA 1CTEA 3IV2A 1DKIA 4YYRA 1GECE 3PT2A 4OVZA 3MTVA 3KSEA 5CVNB 4P6EA 3OVZA 2AIMA 2R9MA 1GCBA 1PIPA 1TU6A 1AU0A 3QJ3A 3ERVA 2FYEA 4YYUA 4MZSA 9PAPA 1ME3A 2UZJA 2P86A 4CZWA 4W5CA 3BC3A 2CIOA 2PNSA 2G6DA 1SNKA 4XR7A 4MZOA 1QDQA 1BY8A 3QSDA 4BOQA 4CDEB 2ATOA 3KFQA 2P0RA 4MI7A 3PHXA 2NQGA 4Q8HA 1YK8A 1EWMA 1NLJA 1YT7A 3ZNHA 2AYOA 1Q6KA 3E9SA 2Y5BA 5F02A 1PADA 1ICFA 2B1NA 3RVVA 3I3TA 1KFXL 3N3KA 3KX1A 4W4UA 4P16A 4RF0A 5J94A 3H6SA 2E01A 1NL6A 3RNVA 2VHSA 4BOPA 1JQPA 3OQCA 3BWKA 3BB7A 1FH0A 3HD3A 2WBFX 4IP3A 3OF9A 3PBHA 1EWPA 1SP4B 1U9XA 3S3QA 2YJBA 2E02A 1HUCB 5CVMA 1PE6A 2FT2A 3KWBX 4YV8A 3D6SA 3PHUA 4BS6A 1ZCMA 1F2AA 2FRQA 3W30A 2ARYA 1X9YA 1NPZA 2HH5A 4OELA 3LXSA 4BPVA 3HHIA 1DF0A 3F75A 3CH3X 1CS8A 4D8EA 4X6JA 3PHWA 2FUDA 1PVJA 5CHTA 3CH2X 1AU4A 1IWDA 3OISA 1U9WA 4XUIA 3IMAA 3QT4A 3S3RA 4IUMA 4M0WA 1MHWA 1QMYA 3MJ5A 5JA7A 3V6EA 5JZEA 2BDZA 3TMPA 2JQFR 5CVOB 1PPNA 1S4VA 3N4CA 1AECA 2F1GA 4OVZB 1QOLA 3IHPA 2R9CA 2Z84A 1GLOA 1NB3A 4AXLA 4FK5A 3IUTA 2GHUA 3BPMA 2AYNA 4ZTBA 1CQDA 2YJCA 1AYUA 1AYVA 1PPDA 2DCCA 2FQ9A 4OEMA 2YJ2A 3BOWA
chains in the Genus database with same CATH topology
3F5VA 3H8BA 1AU2A 1MS6A 1ME4A 4YVAA 3PDFA 5A24A 2IBIA 3TNXA 1PBHA 1W4TA 2P7UA 4RY2A 1F2CA 2G8EA 3P5WA 2R9NA 3MTNA 2VFBA 2H7JA 4DMXA 4N8WA 3N3GA 1M6DA 4PP2E 1DEUA 4W5BA 3MORA 3BPFA 2VFCA 4P6GA 2XU1A 3KWZA 4QRXA 4PI3A 1U9VA 3IOQA 3K24A 3MHHA 1MDWA 2PBHA 3WXGA 2DZYA 2GFOA 4BS5A 4KLBA 3M99A 4CDCB 3P5UA 1PPPA 1Y08A 2XU4A 4MSXA 2G8JA 4DMYA 4X6HA 3DF0A 3O1GA 2AUZA 2DCAA 3IEJA 2AVWA 1CVZA 1GMYA 2DCBA 4QBBA 3RVXA 5FPWA 1MEMA 2B1MA 3PNRA 4AXMA 3ZUAA 4HWYA 1W5RA 2XU5A 1ITOA 3H7DA 1TL9A 5EGWA 2R9FA 1BP4A 1BGOA 4QRVA 5PADA 3V6CA 1CPJA 4YYQA 3E1ZB 1KXRA 1U9QX 4K7CA 1AIMA 6PADA 2JQGR 1STFE 4G54A 4N79A 1VSNA 2DC6A 2HD5A 1ZIVA 1EF7A 1KHPA 2E00A 2PREA 1O0EA 4I05A 4N4ZA 8PCHA 4I04A 2DC8A 4BSQA 2BSZA 4PP1A 3P5VA 2XU3A 3O0UA 1U5IA 4CDDB 2OULA 1YK7A 1THEA 2G7YA 3P5XA 4PADA 2C0YA 1NQCA 2DJGB 2AU1A 2DCDA 2DJFB 3CBJA 3WXEA 2OZ2A 2BDLA 3BCNA 2DC7A 1CSBB 1XKGA 2CB5A 2PADA 3LFYA 5JH3A 2AUXA 4WA6A 3LTWA 2F7DA 1F2BA 4I07A 3KKUA 4C5PA 4QH6A 1TLOA 3KW9A 1CV8A 2O6XA 3I06A 3U8EA 3HWNA 4QRGA 2HXZA 1AYWA 1A6RA 2ACTA 2FO5A 1Y4HA 2Y6EA 2NQAA 3H8CA 1PCIA 1KHQA 2YJ9A 3HHAA 2R6NA 3K8UA 3OF8A 1K3BB 1AU3A 4YYVA 4YYSA 4BQVA 2R9OA 1EWLA 3AI8A 4CDFB 2HHNA 2OP3A 3PW3A 1YALA 7PCKA 1MEGA 3USVA 4Q8GA 4ZUXU 3NHEA 3H89A 2E03A 3MHSA 1BQIA 1PPOA 1PXVA 1POPA 2FRAA 4YYWA 1VJVA 1GX3A 1YVBA 1F29A 3K9MA 1MIRA 1CB5A 1EWOA 5EF4A 2IPPB 3CBKA 5CHVA 2NQDB 2YJ8A 1QXPA 3OVXA 3B79A 2AS8A 4FIPA 2DC9A 2DZZA 2FTDA 5K16A 3WXFA 3RVWA 1CJLA 1ATKA 4X6IA 3C9EA 3GCBA 1NB5A 1KFUL 2VHFA 2NQIA 4FJCA 1CTEA 4BGFA 3IV2A 4YYRA 1GECE 5CVNB 3KSEA 4P6EA 3OVZA 2AIMA 2R9MA 4GUZA 1GCBA 1PIPA 1TU6A 1AU0A 4NV8A 3QJ3A 3ERVA 2FYEA 4YYUA 4MZSA 9PAPA 1ME3A 4CZWA 2P86A 1E2TA 4W5CA 3BC3A 2CIOA 2PNSA 2G6DA 1SNKA 4XR7A 4MZOA 1QDQA 1BY8A 3QSDA 4CDEB 2ATOA 3KFQA 2P0RA 2NQGA 4Q8HA 1YK8A 1EWMA 1NLJA 1YT7A 2AYOA 1Q6KA 2Y5BA 5F02A 1PADA 1ICFA 2B1NA 3RVVA 3I3TA 1KFXL 3N3KA 3KX1A 4W4UA 5J94A 3H6SA 2E01A 1NL6A 4B55A 1W6FA 2VHSA 1JQPA 3BWKA 1FH0A 3HD3A 2WBFX 3OF9A 3PBHA 1EWPA 1SP4B 1U9XA 3S3QA 2YJBA 2E02A 1HUCB 5CVMA 1PE6A 2FT2A 3KWBX 4YV8A 3D6SA 4BS6A 1ZCMA 1F2AA 2FRQA 2ARYA 1X9YA 1NPZA 2HH5A 4OELA 3LXSA 4BPVA 3HHIA 1DF0A 3F75A 3CH3X 1CS8A 4X6JA 2FUDA 5CHTA 3CH2X 1AU4A 1IWDA 3OISA 1U9WA 4XUIA 3IMAA 3QT4A 3S3RA 1MHWA 1QMYA 5JA7A 3V6EA 2BDZA 2JQFR 5CVOB 1PPNA 1S4VA 3N4CA 1AECA 4NV7A 2F1GA 1QOLA 3IHPA 2R9CA 1GLOA 1NB3A 4AXLA 4FK5A 3IUTA 3D9WA 2GHUA 3BPMA 2AYNA 1CQDA 2YJCA 1AYUA 1AYVA 1PPDA 2DCCA 2FQ9A 4OEMA 2YJ2A 3BOWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3F5V A;  3H8B A;  1AU2 A;  1MS6 A;  1ME4 A;  4YVA A;  3PDF A;  5A24 A;  2IBI A;  3TNX A;  1PBH A;  2P7U A;  4RY2 A;  1F2C A;  2G8E A;  3P5W A;  2R9N A;  3MTN A;  2H7J A;  4DMX A;  4N8W A;  3N3G A;  1M6D A;  4PP2 E;  1DEU A;  4W5B A;  3MOR A;  3BPF A;  4P6G A;  2XU1 A;  3KWZ A;  4QRX A;  4PI3 A;  1U9V A;  3IOQ A;  3K24 A;  3MHH A;  1MDW A;  2PBH A;  3WXG A;  2DZY A;  2GFO A;  4BS5 A;  4KLB A;  3M99 A;  4CDC B;  3P5U A;  1PPP A;  1Y08 A;  2XU4 A;  4MSX A;  2G8J A;  4DMY A;  4X6H A;  3DF0 A;  3O1G A;  2AUZ A;  2DCA A;  3IEJ A;  2AVW A;  1CVZ A;  1GMY A;  2DCB A;  4QBB A;  3RVX A;  5FPW A;  1MEM A;  2B1M A;  3PNR A;  4AXM A;  3ZUA A;  4HWY A;  2XU5 A;  1ITO A;  3H7D A;  1TL9 A;  5EGW A;  2R9F A;  1BP4 A;  1BGO A;  4QRV A;  5PAD A;  3V6C A;  1CPJ A;  4YYQ A;  3E1Z B;  1KXR A;  1U9Q X;  4K7C A;  1AIM A;  6PAD A;  2JQG R;  1STF E;  4G54 A;  4N79 A;  1VSN A;  2DC6 A;  2HD5 A;  1ZIV A;  1EF7 A;  1KHP A;  2E00 A;  2PRE A;  1O0E A;  4I05 A;  4N4Z A;  8PCH A;  4I04 A;  2DC8 A;  4BSQ A;  4PP1 A;  3P5V A;  2XU3 A;  3O0U A;  1U5I A;  4CDD B;  2OUL A;  1YK7 A;  1THE A;  2G7Y A;  3P5X A;  4PAD A;  2C0Y A;  1NQC A;  2DJG B;  2AU1 A;  2DCD A;  2DJF B;  3CBJ A;  3WXE A;  2OZ2 A;  2BDL A;  3BCN A;  2DC7 A;  1CSB B;  1XKG A;  2CB5 A;  2PAD A;  3LFY A;  5JH3 A;  2AUX A;  4WA6 A;  2F7D A;  1F2B A;  4I07 A;  3KKU A;  4QH6 A;  1TLO A;  3KW9 A;  1CV8 A;  2O6X A;  3I06 A;  3U8E A;  3HWN A;  4QRG A;  2HXZ A;  1AYW A;  1A6R A;  2ACT A;  2FO5 A;  1Y4H A;  2Y6E A;  2NQA A;  3H8C A;  1PCI A;  1KHQ A;  2YJ9 A;  3HHA A;  2R6N A;  3K8U A;  3OF8 A;  1K3B B;  1AU3 A;  4YYV A;  4YYS A;  4BQV A;  2R9O A;  1EWL A;  3AI8 A;  4CDF B;  2HHN A;  2OP3 A;  3PW3 A;  1YAL A;  7PCK A;  1MEG A;  3USV A;  4Q8G A;  4ZUX U;  3NHE A;  3H89 A;  2E03 A;  3MHS A;  1BQI A;  1PPO A;  1PXV A;  1POP A;  2FRA A;  4YYW A;  1VJV A;  1YVB A;  1F29 A;  3K9M A;  1MIR A;  1CB5 A;  1EWO A;  5EF4 A;  2IPP B;  3CBK A;  5CHV A;  2NQD B;  2YJ8 A;  1QXP A;  3OVX A;  3B79 A;  2AS8 A;  4FIP A;  2DC9 A;  2DZZ A;  2FTD A;  5K16 A;  3WXF A;  3RVW A;  1CJL A;  1ATK A;  4X6I A;  3C9E A;  3GCB A;  1NB5 A;  1KFU L;  2VHF A;  2NQI A;  4FJC A;  1CTE A;  3IV2 A;  4YYR A;  1GEC E;  5CVN B;  3KSE A;  4P6E A;  3OVZ A;  2AIM A;  2R9M A;  1GCB A;  1PIP A;  1TU6 A;  1AU0 A;  3QJ3 A;  3ERV A;  2FYE A;  4YYU A;  4MZS A;  9PAP A;  1ME3 A;  4CZW A;  2P86 A;  4W5C A;  3BC3 A;  2CIO A;  2PNS A;  2G6D A;  1SNK A;  4XR7 A;  4MZO A;  1QDQ A;  1BY8 A;  3QSD A;  4CDE B;  2ATO A;  3KFQ A;  2P0R A;  2NQG A;  4Q8H A;  1YK8 A;  1EWM A;  1NLJ A;  1YT7 A;  2AYO A;  1Q6K A;  2Y5B A;  5F02 A;  1PAD A;  1ICF A;  2B1N A;  3RVV A;  3I3T A;  1KFX L;  3N3K A;  3KX1 A;  4W4U A;  5J94 A;  3H6S A;  2E01 A;  1NL6 A;  2VHS A;  1JQP A;  3BWK A;  1FH0 A;  3HD3 A;  2WBF X;  3OF9 A;  3PBH A;  1EWP A;  1SP4 B;  1U9X A;  3S3Q A;  2YJB A;  2E02 A;  1HUC B;  5CVM A;  1PE6 A;  2FT2 A;  3KWB X;  4YV8 A;  3D6S A;  4BS6 A;  1ZCM A;  1F2A A;  2FRQ A;  2ARY A;  1X9Y A;  1NPZ A;  2HH5 A;  4OEL A;  3LXS A;  4BPV A;  3HHI A;  1DF0 A;  3F75 A;  3CH3 X;  1CS8 A;  4X6J A;  2FUD A;  5CHT A;  3CH2 X;  1AU4 A;  1IWD A;  3OIS A;  1U9W A;  4XUI A;  3IMA A;  3QT4 A;  3S3R A;  1MHW A;  1QMY A;  5JA7 A;  3V6E A;  2BDZ A;  2JQF R;  5CVO B;  1PPN A;  1S4V A;  3N4C A;  1AEC A;  2F1G A;  1QOL A;  3IHP A;  2R9C A;  1GLO A;  1NB3 A;  4AXL A;  4FK5 A;  3IUT A;  2GHU A;  3BPM A;  2AYN A;  1CQD A;  2YJC A;  1AYU A;  1AYV A;  1PPD A;  2DCC A;  2FQ9 A;  4OEM A;  2YJ2 A;  3BOW A; 
#chains in the Genus database with same CATH topology
 3F5V A;  3H8B A;  4OW0 A;  1AU2 A;  1MS6 A;  1ME4 A;  4YVA A;  3W31 A;  3PDF A;  5A24 A;  2IBI A;  3BBA A;  3TNX A;  1PBH A;  2BU3 A;  2P7U A;  1F2C A;  4RY2 A;  2G8E A;  3C0R A;  3P5W A;  2BTW B;  2R9N A;  3MTN A;  2H7J A;  4DMX A;  4N8W A;  3N3G A;  1M6D A;  4PP2 E;  1DEU A;  4W5B A;  3MOR A;  2HWK A;  3BPF A;  4P6G A;  4R3D A;  4WUR A;  2XU1 A;  3PRP A;  3KWZ A;  3PRM A;  4QRX A;  4PI3 A;  1U9V A;  3IOQ A;  4RKX A;  3K24 A;  3MHH A;  4D8B A;  1MDW A;  2PBH A;  3WXG A;  2FE8 A;  2DZY A;  2GFO A;  4BS5 A;  4KLB A;  3M99 A;  4CDC B;  3P5U A;  1PPP A;  1Y08 A;  1UKF A;  2XU4 A;  4MSX A;  2G8J A;  5KO3 A;  4DMY A;  4X6H A;  3DF0 A;  3MP2 A;  3O1G A;  2AUZ A;  2DCA A;  3IEJ A;  2AVW A;  1CVZ A;  1GMY A;  2DCB A;  4QBB A;  3RVX A;  5FPW A;  1MEM A;  2B1M A;  3PNR A;  4AXM A;  3PSE A;  4REZ A;  3ZUA A;  4GUA A;  4HWY A;  2XU5 A;  1ITO A;  3H7D A;  4HXD B;  2J7Q A;  1TL9 A;  5EGW A;  2R9F A;  1BP4 A;  1BGO A;  4QRV A;  5PAD A;  3V6C A;  1CPJ A;  4YYQ A;  3E1Z B;  1KXR A;  1U9Q X;  4K7C A;  1AIM A;  6PAD A;  2JQG R;  1STF E;  4G54 A;  4N79 A;  1VSN A;  2DC6 A;  2HD5 A;  1ZIV A;  4BOU A;  1EF7 A;  1KHP A;  2E00 A;  2PRE A;  1O0E A;  4I05 A;  4N4Z A;  8PCH A;  4I04 A;  3B21 A;  4RF1 A;  2DC8 A;  2JRI A;  4BSQ A;  2DOS A;  4PP1 A;  3P5V A;  2XU3 A;  3O0U A;  1U5I A;  4CDD B;  2OUL A;  1YK7 A;  1THE A;  4BOZ A;  2G7Y A;  3P5X A;  4PAD A;  2C0Y A;  1NQC A;  4MM3 B;  2DJG B;  4XZX A;  2AU1 A;  2DCD A;  2DJF B;  3CBJ A;  3WXE A;  2J7Q C;  2OZ2 A;  2BDL A;  3TRK A;  3BCN A;  5EZQ A;  2DC7 A;  1CSB B;  1XKG A;  2CB5 A;  2PAD A;  3LFY A;  5JH3 A;  2AUX A;  4WA6 A;  2F7D A;  1F2B A;  3IFU A;  2BTW A;  4I07 A;  3KKU A;  4QH6 A;  1TLO A;  3KW9 A;  2AGA A;  1CV8 A;  2O6X A;  3I06 A;  3U8E A;  3HWN A;  4QRG A;  3O65 A;  2HXZ A;  1AYW A;  1A6R A;  2ACT A;  2FO5 A;  1Y4H A;  2Y6E A;  2NQA A;  3H8C A;  1PCI A;  1KHQ A;  2YJ9 A;  3HHA A;  2R6N A;  4PT5 A;  4RNA A;  5E6J A;  3K8U A;  3OF8 A;  1K3B B;  1AU3 A;  4YYV A;  4YYS A;  4BQV A;  2R9O A;  1EWL A;  3AI8 A;  4CDF B;  2HHN A;  2OP3 A;  3PW3 A;  1YAL A;  4D8I A;  7PCK A;  1MEG A;  3USV A;  4Q8G A;  4ZUX U;  3NHE A;  3H89 A;  2E03 A;  3MHS A;  1BQI A;  1PPO A;  1PXV A;  1POP A;  2FRA A;  4YYW A;  1VJV A;  1YVB A;  1F29 A;  3K9M A;  4A5U A;  1MIR A;  1CB5 A;  1EWO A;  5EF4 A;  2IPP B;  3BY4 A;  3CBK A;  5CHV A;  2NQD B;  2YJ8 A;  1QXP A;  3OVX A;  3B79 A;  2AS8 A;  4FIP A;  2DC9 A;  2DZZ A;  2FTD A;  5K16 A;  3WXF A;  5EZS A;  4BOS A;  3RVW A;  1CJL A;  1ATK A;  4X6I A;  2JTC A;  3C9E A;  3GCB A;  1NB5 A;  1YZB A;  1KFU L;  2VHF A;  2NQI A;  4FJC A;  1CTE A;  3IV2 A;  1DKI A;  4YYR A;  1GEC E;  3PT2 A;  4OVZ A;  3MTV A;  3KSE A;  5CVN B;  4P6E A;  3OVZ A;  2AIM A;  2R9M A;  1GCB A;  1PIP A;  1TU6 A;  1AU0 A;  3QJ3 A;  3ERV A;  2FYE A;  4YYU A;  4MZS A;  9PAP A;  1ME3 A;  2UZJ A;  2P86 A;  4CZW A;  4W5C A;  3BC3 A;  2CIO A;  2PNS A;  2G6D A;  1SNK A;  4XR7 A;  4MZO A;  1QDQ A;  1BY8 A;  3QSD A;  4BOQ A;  4CDE B;  2ATO A;  3KFQ A;  2P0R A;  4MI7 A;  3PHX A;  2NQG A;  4Q8H A;  1YK8 A;  1EWM A;  1NLJ A;  1YT7 A;  3ZNH A;  2AYO A;  1Q6K A;  3E9S A;  2Y5B A;  5F02 A;  1PAD A;  1ICF A;  2B1N A;  3RVV A;  3I3T A;  1KFX L;  3N3K A;  3KX1 A;  4W4U A;  4P16 A;  4RF0 A;  5J94 A;  3H6S A;  2E01 A;  1NL6 A;  3RNV A;  2VHS A;  4BOP A;  1JQP A;  3OQC A;  3BWK A;  3BB7 A;  1FH0 A;  3HD3 A;  2WBF X;  4IP3 A;  3OF9 A;  3PBH A;  1EWP A;  1SP4 B;  1U9X A;  3S3Q A;  2YJB A;  2E02 A;  1HUC B;  5CVM A;  1PE6 A;  2FT2 A;  3KWB X;  4YV8 A;  3D6S A;  3PHU A;  4BS6 A;  1ZCM A;  1F2A A;  2FRQ A;  3W30 A;  2ARY A;  1X9Y A;  1NPZ A;  2HH5 A;  4OEL A;  3LXS A;  4BPV A;  3HHI A;  1DF0 A;  3F75 A;  3CH3 X;  1CS8 A;  4D8E A;  4X6J A;  3PHW A;  2FUD A;  1PVJ A;  5CHT A;  3CH2 X;  1AU4 A;  1IWD A;  3OIS A;  1U9W A;  4XUI A;  3IMA A;  3QT4 A;  3S3R A;  4IUM A;  4M0W A;  1MHW A;  1QMY A;  3MJ5 A;  5JA7 A;  3V6E A;  5JZE A;  2BDZ A;  3TMP A;  2JQF R;  5CVO B;  1PPN A;  1S4V A;  3N4C A;  1AEC A;  2F1G A;  4OVZ B;  1QOL A;  3IHP A;  2R9C A;  2Z84 A;  1GLO A;  1NB3 A;  4AXL A;  4FK5 A;  3IUT A;  2GHU A;  3BPM A;  2AYN A;  4ZTB A;  1CQD A;  2YJC A;  1AYU A;  1AYV A;  1PPD A;  2DCC A;  2FQ9 A;  4OEM A;  2YJ2 A;  3BOW A; 
#chains in the Genus database with same CATH homology
 3F5V A;  3H8B A;  1AU2 A;  1MS6 A;  1ME4 A;  4YVA A;  3PDF A;  5A24 A;  2IBI A;  3TNX A;  1PBH A;  1W4T A;  2P7U A;  4RY2 A;  1F2C A;  2G8E A;  3P5W A;  2R9N A;  3MTN A;  2VFB A;  2H7J A;  4DMX A;  4N8W A;  3N3G A;  1M6D A;  4PP2 E;  1DEU A;  4W5B A;  3MOR A;  3BPF A;  2VFC A;  4P6G A;  2XU1 A;  3KWZ A;  4QRX A;  4PI3 A;  1U9V A;  3IOQ A;  3K24 A;  3MHH A;  1MDW A;  2PBH A;  3WXG A;  2DZY A;  2GFO A;  4BS5 A;  4KLB A;  3M99 A;  4CDC B;  3P5U A;  1PPP A;  1Y08 A;  2XU4 A;  4MSX A;  2G8J A;  4DMY A;  4X6H A;  3DF0 A;  3O1G A;  2AUZ A;  2DCA A;  3IEJ A;  2AVW A;  1CVZ A;  1GMY A;  2DCB A;  4QBB A;  3RVX A;  5FPW A;  1MEM A;  2B1M A;  3PNR A;  4AXM A;  3ZUA A;  4HWY A;  1W5R A;  2XU5 A;  1ITO A;  3H7D A;  1TL9 A;  5EGW A;  2R9F A;  1BP4 A;  1BGO A;  4QRV A;  5PAD A;  3V6C A;  1CPJ A;  4YYQ A;  3E1Z B;  1KXR A;  1U9Q X;  4K7C A;  1AIM A;  6PAD A;  2JQG R;  1STF E;  4G54 A;  4N79 A;  1VSN A;  2DC6 A;  2HD5 A;  1ZIV A;  1EF7 A;  1KHP A;  2E00 A;  2PRE A;  1O0E A;  4I05 A;  4N4Z A;  8PCH A;  4I04 A;  2DC8 A;  4BSQ A;  2BSZ A;  4PP1 A;  3P5V A;  2XU3 A;  3O0U A;  1U5I A;  4CDD B;  2OUL A;  1YK7 A;  1THE A;  2G7Y A;  3P5X A;  4PAD A;  2C0Y A;  1NQC A;  2DJG B;  2AU1 A;  2DCD A;  2DJF B;  3CBJ A;  3WXE A;  2OZ2 A;  2BDL A;  3BCN A;  2DC7 A;  1CSB B;  1XKG A;  2CB5 A;  2PAD A;  3LFY A;  5JH3 A;  2AUX A;  4WA6 A;  3LTW A;  2F7D A;  1F2B A;  4I07 A;  3KKU A;  4C5P A;  4QH6 A;  1TLO A;  3KW9 A;  1CV8 A;  2O6X A;  3I06 A;  3U8E A;  3HWN A;  4QRG A;  2HXZ A;  1AYW A;  1A6R A;  2ACT A;  2FO5 A;  1Y4H A;  2Y6E A;  2NQA A;  3H8C A;  1PCI A;  1KHQ A;  2YJ9 A;  3HHA A;  2R6N A;  3K8U A;  3OF8 A;  1K3B B;  1AU3 A;  4YYV A;  4YYS A;  4BQV A;  2R9O A;  1EWL A;  3AI8 A;  4CDF B;  2HHN A;  2OP3 A;  3PW3 A;  1YAL A;  7PCK A;  1MEG A;  3USV A;  4Q8G A;  4ZUX U;  3NHE A;  3H89 A;  2E03 A;  3MHS A;  1BQI A;  1PPO A;  1PXV A;  1POP A;  2FRA A;  4YYW A;  1VJV A;  1GX3 A;  1YVB A;  1F29 A;  3K9M A;  1MIR A;  1CB5 A;  1EWO A;  5EF4 A;  2IPP B;  3CBK A;  5CHV A;  2NQD B;  2YJ8 A;  1QXP A;  3OVX A;  3B79 A;  2AS8 A;  4FIP A;  2DC9 A;  2DZZ A;  2FTD A;  5K16 A;  3WXF A;  3RVW A;  1CJL A;  1ATK A;  4X6I A;  3C9E A;  3GCB A;  1NB5 A;  1KFU L;  2VHF A;  2NQI A;  4FJC A;  1CTE A;  4BGF A;  3IV2 A;  4YYR A;  1GEC E;  5CVN B;  3KSE A;  4P6E A;  3OVZ A;  2AIM A;  2R9M A;  4GUZ A;  1GCB A;  1PIP A;  1TU6 A;  1AU0 A;  4NV8 A;  3QJ3 A;  3ERV A;  2FYE A;  4YYU A;  4MZS A;  9PAP A;  1ME3 A;  4CZW A;  2P86 A;  1E2T A;  4W5C A;  3BC3 A;  2CIO A;  2PNS A;  2G6D A;  1SNK A;  4XR7 A;  4MZO A;  1QDQ A;  1BY8 A;  3QSD A;  4CDE B;  2ATO A;  3KFQ A;  2P0R A;  2NQG A;  4Q8H A;  1YK8 A;  1EWM A;  1NLJ A;  1YT7 A;  2AYO A;  1Q6K A;  2Y5B A;  5F02 A;  1PAD A;  1ICF A;  2B1N A;  3RVV A;  3I3T A;  1KFX L;  3N3K A;  3KX1 A;  4W4U A;  5J94 A;  3H6S A;  2E01 A;  1NL6 A;  4B55 A;  1W6F A;  2VHS A;  1JQP A;  3BWK A;  1FH0 A;  3HD3 A;  2WBF X;  3OF9 A;  3PBH A;  1EWP A;  1SP4 B;  1U9X A;  3S3Q A;  2YJB A;  2E02 A;  1HUC B;  5CVM A;  1PE6 A;  2FT2 A;  3KWB X;  4YV8 A;  3D6S A;  4BS6 A;  1ZCM A;  1F2A A;  2FRQ A;  2ARY A;  1X9Y A;  1NPZ A;  2HH5 A;  4OEL A;  3LXS A;  4BPV A;  3HHI A;  1DF0 A;  3F75 A;  3CH3 X;  1CS8 A;  4X6J A;  2FUD A;  5CHT A;  3CH2 X;  1AU4 A;  1IWD A;  3OIS A;  1U9W A;  4XUI A;  3IMA A;  3QT4 A;  3S3R A;  1MHW A;  1QMY A;  5JA7 A;  3V6E A;  2BDZ A;  2JQF R;  5CVO B;  1PPN A;  1S4V A;  3N4C A;  1AEC A;  4NV7 A;  2F1G A;  1QOL A;  3IHP A;  2R9C A;  1GLO A;  1NB3 A;  4AXL A;  4FK5 A;  3IUT A;  3D9W A;  2GHU A;  3BPM A;  2AYN A;  1CQD A;  2YJC A;  1AYU A;  1AYV A;  1PPD A;  2DCC A;  2FQ9 A;  4OEM A;  2YJ2 A;  3BOW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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