3PSEA

Structure of a viral otu domain protease bound to interferon-stimulated gene 15 (isg15)
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
164
structure length
164
Chain Sequence
GPMDFLRSLDWTQVIAGQYVSNPRFNISDYFEIVRQPGDGNCFYHSIAELTMPNKTDHSYHYIKRLTESAARKYYQEEPEARLVGLSLEDYLKRMLSDNEWGSTLEASMLAKEMGITIIIWTVAASDEVEAGIKFGDGDVFTAVNLLHSGQTHFDALRILPQFE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease.
pubmed doi rcsb
molecule tags Hydrolase/protein binding
source organism Crimean-congo hemorrhagic fever virus
molecule keywords RNA polymerase
total genus 48
structure length 164
sequence length 164
ec nomenclature
pdb deposition date 2010-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02338 OTU OTU-like cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.80 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cathepsin B; Chain A 3pseA00
3PHUA 5JZEA 3PSEA 3PT2A 3TMPA 3PRMA 3ZNHA 4BOSA 4BOUA 4BOPA 3PHWA 3PHXA 3C0RA 4BOQA 3BY4A 4BOZA 3PRPA 4HXDB
chains in the Genus database with same CATH superfamily
5KO3A 1DKIA 3OQCA 2NQGA 2XU3A 4RF0A 3B21A 3M99A 1VJVA 2FUDA 3HHIA 2AU1A 1U9VA 5EGWA 1YVBA 1YK8A 3USVA 1MIRA 2IBIA 4N79A 1PPNA 1PCIA 4REZA 2DJFB 2E02A 3F75A 3PBHA 3OVZA 3N3GA 1Y4HA 1PBHA 2BTWA 2BDLA 3RVXA 2FE8A 3KWBX 4YYVA 4PI3A 4WA6A 3CH2X 2YJ2A 1PIPA 4PP2E 5CVNB 2VHSA 2DCAA 3BCNA 3RNVA 1PXVA 1NL6A 2OZ2A 3IMAA 2G8EA 2R6NA 5CHTA 1U9QX 3MTVA 1FH0A 3RVVA 1GLOA 2G8JA 1AU2A 1EWPA 2DCCA 1BP4A 3TRKA 3OF9A 3I3TA 4HXDB 4Q8HA 2Z84A 2NQIA 3O65A 4PP1A 2ACTA 4XR7A 4BOZA 2C0YA 1KHQA 3MTNA 2O6XA 3W30A 2Y6EA 1QMYA 4I07A 4KLBA 4RKXA 1AIMA 3I06A 1THEA 2FRQA 9PAPA 3QJ3A 1AYVA 5F02A 1F2BA 1GECE 3BC3A 4CDEB 2E01A 2FT2A 1CSBB 5CHVA 1CVZA 4AXLA 3V6CA 1TU6A 3IHPA 2JTCA 3P5VA 1YT7A 2BTWB 3V6EA 4RY2A 3MHHA 1MS6A 3B79A 1AU4A 3F5VA 5EZQA 4XUIA 1GCBA 1ME3A 2Y5BA 1DEUA 1U5IA 4X6IA 1DF0A 3PRPA 1EWLA 4FIPA 4YYQA 4BOUA 4RF1A 5EF4A 2J7QC 5PADA 3IOQA 2R9OA 4CDFB 3C9EA 2OULA 3IFUA 2YJ9A 2YJCA 7PCKA 2YJ8A 5E6JA 3PRMA 4BSQA 4OEMA 3H7DA 4BPVA 3D6SA 3HD3A 4WURA 3MJ5A 2WBFX 2FRAA 2NQAA 1KFUL 5J94A 2JQGR 3H8BA 1F2CA 1ZCMA 1CPJA 4W5BA 2XU5A 2G7YA 2FO5A 1SP4B 2GHUA 1EF7A 3H8CA 3PHXA 2FQ9A 1ICFA 2E00A 4CDCB 3CBKA 3TNXA 4BQVA 1MHWA 1K3BB 3P5UA 1GMYA 1KXRA 2IPPB 1NPZA 1QDQA 3C0RA 4PADA 4BOQA 3W31A 1ATKA 2DOSA 3PSEA 3KX1A 2BDZA 3NHEA 1F2AA 2AGAA 2R9CA 1CTEA 4R3DA 4QRXA 2R9FA 4OW0A 3PW3A 2HXZA 4GUAA 1STFE 4MSXA 1KFXL 1CV8A 1ME4A 3MP2A 3OF8A 4YYUA 3BOWA 2HH5A 2JRIA 1BY8A 3K8UA 2DC6A 3TMPA 1AU3A 2HWKA 3K9MA 2AUXA 3H6SA 1F29A 4XZXA 2AYNA 4CZWA 4YYSA 1CQDA 3WXEA 3H89A 1XKGA 2PADA 3MORA 3GCBA 1AU0A 3WXFA 1MDWA 2CIOA 3LFYA 1ITOA 4I04A 1YALA 3ERVA 1NLJA 1UKFA 4P6GA 1EWOA 4MM3B 1A6RA 2AVWA 2HHNA 3RVWA 3HWNA 4DMXA 1PADA 2OP3A 1KHPA 1Q6KA 1TL9A 3K24A 1S4VA 4Q8GA 1NQCA 3AI8A 3E9SA 4BOPA 2DC7A 2FTDA 4FK5A 4IUMA 3KKUA 4YYRA 3HHAA 4OELA 4M0WA 2P0RA 4YV8A 3CH3X 4QH6A 3N3KA 3O1GA 3IV2A 4IP3A 4YYWA 3WXGA 2AS8A 2R9MA 3P5XA 4W4UA 4YVAA 4HWYA 2PREA 2AUZA 2P7UA 4W5CA 1U9XA 2F7DA 3N4CA 4FJCA 3BBAA 3LXSA 2DC8A 3S3QA 4MZOA 2HD5A 3ZUAA 3BPFA 3P5WA 1X9YA 1PPDA 1BQIA 6PADA 1POPA 2GFOA 3KW9A 3E1ZB 1PPOA 3KSEA 1QXPA 5K16A 2UZJA 1NB3A 2VHFA 4QRGA 5FPWA 3ZNHA 2DJGB 1VSNA 4PT5A 1SNKA 4D8IA 3DF0A 4X6JA 2E03A 2CB5A 3PHUA 5CVOB 1JQPA 2XU4A 3BY4A 1Y08A 4ZUXU 2ATOA 4DMYA 1MEGA 5JH3A 3MHSA 4BOSA 2FYEA 1ZIVA 3PDFA 5CVMA 1NB5A 1AYWA 1O0EA 2B1NA 3BPMA 2F1GA 2XU1A 2G6DA 3BB7A 1IWDA 2DCDA 3IEJA 2H7JA 1PE6A 3OISA 4OVZB 4CDDB 3S3RA 2ARYA 1PPPA 2DC9A 8PCHA 1AECA 4QRVA 2DZZA 3PHWA 4G54A 1MEMA 1EWMA 5JA7A 4MZSA 3IUTA 4BS5A 1U9WA 2BU3A 4K7CA 1TLOA 3KFQA 3QT4A 2JQFR 2P86A 4QBBA 1CS8A 2AIMA 4AXMA 4I05A 1YK7A 3PNRA 1AYUA 1BGOA 1M6DA 1PVJA 2B1MA 1CJLA 2YJBA 3PT2A 4X6HA 1CB5A 4D8EA 2PNSA 2R9NA 4N4ZA 3QSDA 3U8EA 4RNAA 2PBHA 2NQDB 5JZEA 2J7QA 4N8WA 3O0UA 4D8BA 4P16A 1YZBA 4BS6A 4A5UA 3KWZA 1HUCB 2DCBA 5A24A 2DZYA 4MI7A 3OVXA 4P6EA 4ZTBA 3BWKA 1QOLA 4OVZA 2AYOA 5EZSA 3CBJA
chains in the Genus database with same CATH topology
3PHUA 3TMPA 5KO3A 1DKIA 2HWKA 4XZXA 3OQCA 3BY4A 3PRPA 4RF0A 3B21A 4BOUA 4BOSA 4RF1A 2J7QC 1UKFA 4REZA 4MM3B 3IFUA 5E6JA 3PRMA 3BB7A 2BTWA 4WURA 3MJ5A 2FE8A 4OVZB 3E9SA 4BOPA 3PHWA 4IUMA 4M0WA 3RNVA 3PHXA 4IP3A 3MTVA 2BU3A 3TRKA 4HXDB 2Z84A 1PVJA 3O65A 3C0RA 4BOQA 3W31A 4BOZA 2DOSA 3PSEA 3PT2A 3W30A 2AGAA 4R3DA 4D8EA 3BBAA 4RKXA 4OW0A 4RNAA 4GUAA 5JZEA 2J7QA 4D8BA 4P16A 1YZBA 2UZJA 4A5UA 3ZNHA 2JTCA 2BTWB 4MI7A 4PT5A 4D8IA 3MP2A 4ZTBA 5EZQA 4OVZA 2JRIA 5EZSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PHU A;  5JZE A;  3PSE A;  3PT2 A;  3TMP A;  3PRM A;  3ZNH A;  4BOS A;  4BOU A;  4BOP A;  3PHW A;  3PHX A;  3C0R A;  4BOQ A;  3BY4 A;  4BOZ A;  3PRP A;  4HXD B; 
#chains in the Genus database with same CATH topology
 5KO3 A;  1DKI A;  3OQC A;  2NQG A;  2XU3 A;  4RF0 A;  3B21 A;  3M99 A;  1VJV A;  2FUD A;  3HHI A;  2AU1 A;  1U9V A;  5EGW A;  1YVB A;  1YK8 A;  3USV A;  1MIR A;  2IBI A;  4N79 A;  1PPN A;  1PCI A;  4REZ A;  2DJF B;  2E02 A;  3F75 A;  3PBH A;  3OVZ A;  3N3G A;  1Y4H A;  1PBH A;  2BTW A;  2BDL A;  3RVX A;  2FE8 A;  3KWB X;  4YYV A;  4PI3 A;  4WA6 A;  3CH2 X;  2YJ2 A;  1PIP A;  4PP2 E;  5CVN B;  2VHS A;  2DCA A;  3BCN A;  3RNV A;  1PXV A;  1NL6 A;  2OZ2 A;  3IMA A;  2G8E A;  2R6N A;  5CHT A;  1U9Q X;  3MTV A;  1FH0 A;  3RVV A;  1GLO A;  2G8J A;  1AU2 A;  1EWP A;  2DCC A;  1BP4 A;  3TRK A;  3OF9 A;  3I3T A;  4HXD B;  4Q8H A;  2Z84 A;  2NQI A;  3O65 A;  4PP1 A;  2ACT A;  4XR7 A;  4BOZ A;  2C0Y A;  1KHQ A;  3MTN A;  2O6X A;  3W30 A;  2Y6E A;  1QMY A;  4I07 A;  4KLB A;  4RKX A;  1AIM A;  3I06 A;  1THE A;  2FRQ A;  9PAP A;  3QJ3 A;  1AYV A;  5F02 A;  1F2B A;  1GEC E;  3BC3 A;  4CDE B;  2E01 A;  2FT2 A;  1CSB B;  5CHV A;  1CVZ A;  4AXL A;  3V6C A;  1TU6 A;  3IHP A;  2JTC A;  3P5V A;  1YT7 A;  2BTW B;  3V6E A;  4RY2 A;  3MHH A;  1MS6 A;  3B79 A;  1AU4 A;  3F5V A;  5EZQ A;  4XUI A;  1GCB A;  1ME3 A;  2Y5B A;  1DEU A;  1U5I A;  4X6I A;  1DF0 A;  3PRP A;  1EWL A;  4FIP A;  4YYQ A;  4BOU A;  4RF1 A;  5EF4 A;  2J7Q C;  5PAD A;  3IOQ A;  2R9O A;  4CDF B;  3C9E A;  2OUL A;  3IFU A;  2YJ9 A;  2YJC A;  7PCK A;  2YJ8 A;  5E6J A;  3PRM A;  4BSQ A;  4OEM A;  3H7D A;  4BPV A;  3D6S A;  3HD3 A;  4WUR A;  3MJ5 A;  2WBF X;  2FRA A;  2NQA A;  1KFU L;  5J94 A;  2JQG R;  3H8B A;  1F2C A;  1ZCM A;  1CPJ A;  4W5B A;  2XU5 A;  2G7Y A;  2FO5 A;  1SP4 B;  2GHU A;  1EF7 A;  3H8C A;  3PHX A;  2FQ9 A;  1ICF A;  2E00 A;  4CDC B;  3CBK A;  3TNX A;  4BQV A;  1MHW A;  1K3B B;  3P5U A;  1GMY A;  1KXR A;  2IPP B;  1NPZ A;  1QDQ A;  3C0R A;  4PAD A;  4BOQ A;  3W31 A;  1ATK A;  2DOS A;  3PSE A;  3KX1 A;  2BDZ A;  3NHE A;  1F2A A;  2AGA A;  2R9C A;  1CTE A;  4R3D A;  4QRX A;  2R9F A;  4OW0 A;  3PW3 A;  2HXZ A;  4GUA A;  1STF E;  4MSX A;  1KFX L;  1CV8 A;  1ME4 A;  3MP2 A;  3OF8 A;  4YYU A;  3BOW A;  2HH5 A;  2JRI A;  1BY8 A;  3K8U A;  2DC6 A;  3TMP A;  1AU3 A;  2HWK A;  3K9M A;  2AUX A;  3H6S A;  1F29 A;  4XZX A;  2AYN A;  4CZW A;  4YYS A;  1CQD A;  3WXE A;  3H89 A;  1XKG A;  2PAD A;  3MOR A;  3GCB A;  1AU0 A;  3WXF A;  1MDW A;  2CIO A;  3LFY A;  1ITO A;  4I04 A;  1YAL A;  3ERV A;  1NLJ A;  1UKF A;  4P6G A;  1EWO A;  4MM3 B;  1A6R A;  2AVW A;  2HHN A;  3RVW A;  3HWN A;  4DMX A;  1PAD A;  2OP3 A;  1KHP A;  1Q6K A;  1TL9 A;  3K24 A;  1S4V A;  4Q8G A;  1NQC A;  3AI8 A;  3E9S A;  4BOP A;  2DC7 A;  2FTD A;  4FK5 A;  4IUM A;  3KKU A;  4YYR A;  3HHA A;  4OEL A;  4M0W A;  2P0R A;  4YV8 A;  3CH3 X;  4QH6 A;  3N3K A;  3O1G A;  3IV2 A;  4IP3 A;  4YYW A;  3WXG A;  2AS8 A;  2R9M A;  3P5X A;  4W4U A;  4YVA A;  4HWY A;  2PRE A;  2AUZ A;  2P7U A;  4W5C A;  1U9X A;  2F7D A;  3N4C A;  4FJC A;  3BBA A;  3LXS A;  2DC8 A;  3S3Q A;  4MZO A;  2HD5 A;  3ZUA A;  3BPF A;  3P5W A;  1X9Y A;  1PPD A;  1BQI A;  6PAD A;  1POP A;  2GFO A;  3KW9 A;  3E1Z B;  1PPO A;  3KSE A;  1QXP A;  5K16 A;  2UZJ A;  1NB3 A;  2VHF A;  4QRG A;  5FPW A;  3ZNH A;  2DJG B;  1VSN A;  4PT5 A;  1SNK A;  4D8I A;  3DF0 A;  4X6J A;  2E03 A;  2CB5 A;  3PHU A;  5CVO B;  1JQP A;  2XU4 A;  3BY4 A;  1Y08 A;  4ZUX U;  2ATO A;  4DMY A;  1MEG A;  5JH3 A;  3MHS A;  4BOS A;  2FYE A;  1ZIV A;  3PDF A;  5CVM A;  1NB5 A;  1AYW A;  1O0E A;  2B1N A;  3BPM A;  2F1G A;  2XU1 A;  2G6D A;  3BB7 A;  1IWD A;  2DCD A;  3IEJ A;  2H7J A;  1PE6 A;  3OIS A;  4OVZ B;  4CDD B;  3S3R A;  2ARY A;  1PPP A;  2DC9 A;  8PCH A;  1AEC A;  4QRV A;  2DZZ A;  3PHW A;  4G54 A;  1MEM A;  1EWM A;  5JA7 A;  4MZS A;  3IUT A;  4BS5 A;  1U9W A;  2BU3 A;  4K7C A;  1TLO A;  3KFQ A;  3QT4 A;  2JQF R;  2P86 A;  4QBB A;  1CS8 A;  2AIM A;  4AXM A;  4I05 A;  1YK7 A;  3PNR A;  1AYU A;  1BGO A;  1M6D A;  1PVJ A;  2B1M A;  1CJL A;  2YJB A;  3PT2 A;  4X6H A;  1CB5 A;  4D8E A;  2PNS A;  2R9N A;  4N4Z A;  3QSD A;  3U8E A;  4RNA A;  2PBH A;  2NQD B;  5JZE A;  2J7Q A;  4N8W A;  3O0U A;  4D8B A;  4P16 A;  1YZB A;  4BS6 A;  4A5U A;  3KWZ A;  1HUC B;  2DCB A;  5A24 A;  2DZY A;  4MI7 A;  3OVX A;  4P6E A;  4ZTB A;  3BWK A;  1QOL A;  4OVZ A;  2AYO A;  5EZS A;  3CBJ A; 
#chains in the Genus database with same CATH homology
 3PHU A;  3TMP A;  5KO3 A;  1DKI A;  2HWK A;  4XZX A;  3OQC A;  3BY4 A;  3PRP A;  4RF0 A;  3B21 A;  4BOU A;  4BOS A;  4RF1 A;  2J7Q C;  1UKF A;  4REZ A;  4MM3 B;  3IFU A;  5E6J A;  3PRM A;  3BB7 A;  2BTW A;  4WUR A;  3MJ5 A;  2FE8 A;  4OVZ B;  3E9S A;  4BOP A;  3PHW A;  4IUM A;  4M0W A;  3RNV A;  3PHX A;  4IP3 A;  3MTV A;  2BU3 A;  3TRK A;  4HXD B;  2Z84 A;  1PVJ A;  3O65 A;  3C0R A;  4BOQ A;  3W31 A;  4BOZ A;  2DOS A;  3PSE A;  3PT2 A;  3W30 A;  2AGA A;  4R3D A;  4D8E A;  3BBA A;  4RKX A;  4OW0 A;  4RNA A;  4GUA A;  5JZE A;  2J7Q A;  4D8B A;  4P16 A;  1YZB A;  2UZJ A;  4A5U A;  3ZNH A;  2JTC A;  2BTW B;  4MI7 A;  4PT5 A;  4D8I A;  3MP2 A;  4ZTB A;  5EZQ A;  4OVZ A;  2JRI A;  5EZS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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