5F02A

Cathepsin l in complex with (2s,4r)-4-(2-chloro-4-methoxy-benzenesulfonyl)-1-[3-(5-chloro-pyridin-2-yl)-azetidine-3-carbonyl]-pyrrolidine-2-carboxylic acid (1-cyano-cyclopropyl)-amide
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
220
structure length
219
Chain Sequence
APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTSDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Cathepsin L1
publication title A Real-World Perspective on Molecular Design.
pubmed doi rcsb
source organism Homo sapiens
total genus 72
structure length 219
sequence length 220
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2015-11-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 5f02A00
1TLOA 4MSXA 2AUZA 1AYUA 2B1MA 1GECE 4CZWA 3WXGA 3HHIA 3BOWA 1AU0A 3N3KA 3B79A 4K7CA 3IUTA 2P86A 1KXRA 2GHUA 1U9VA 1KHQA 1EWOA 2ATOA 4YYVA 1TU6A 1ICFA 4BSQA 2XU1A 6PADA 2WBFX 2B1NA 1MIRA 3M99A 3IEJA 4PP1A 1PCIA 1DF0A 2AUXA 1XKGA 3ZUAA 3HWNA 1QDQA 1PPOA 1U9WA 1NB5A 1AIMA 2FRAA 2OP3A 1STFE 2IPPB 4W4UA 4Q8GA 4AXLA 4HWYA 4FJCA 4QRVA 4QBBA 1ZCMA 1KFUL 3MHHA 3OF8A 1MDWA 1Q6KA 2DZZA 1KHPA 4BPVA 2FUDA 2HH5A 3F75A 5CVMA 2CIOA 2HHNA 2G8JA 2FYEA 2DC9A 3MTNA 1CTEA 3IOQA 3I06A 1ME3A 3I3TA 3RVVA 2O6XA 2H7JA 5CVNB 2AIMA 3KSEA 4WA6A 2XU4A 1GLOA 1AECA 2AYOA 5JA7A 4YV8A 2YJ9A 3E1ZB 2AU1A 1BP4A 2FTDA 2R9NA 3QT4A 4QRXA 2YJ2A 5A24A 2R9OA 4MZOA 3O0UA 2Y6EA 1U5IA 2HD5A 3P5VA 1NQCA 1ATKA 4XUIA 3KKUA 1CPJA 4QH6A 3RVXA 1EWMA 2DZYA 1PXVA 4OELA 1X9YA 1THEA 4YYUA 8PCHA 3P5XA 4QRGA 5J94A 2YJCA 4PI3A 3PDFA 1A6RA 2E03A 3NHEA 3F5VA 5CVOB 2JQFR 2DC6A 1PPDA 3IHPA 3QSDA 1NLJA 1U9XA 2XU3A 3KW9A 5JH3A 4W5CA 2R6NA 3QJ3A 4DMXA 1QMYA 3ERVA 1NB3A 3IMAA 2C0YA 4YYQA 2HXZA 3KX1A 3D6SA 1BY8A 4I04A 1F2CA 2F1GA 5FPWA 2YJBA 2DCCA 1VJVA 4G54A 3S3QA 1PIPA 1EWPA 4YYRA 1AYWA 1KFXL 4DMYA 4Q8HA 1CS8A 3O1GA 2DC8A 3H7DA 2FO5A 2DCBA 1Y08A 1MEMA 1CB5A 1PPPA 4FK5A 4OEMA 1VSNA 3K9MA 4N4ZA 2PREA 3WXFA 1F2BA 1F2AA 2G7YA 1IWDA 1YALA 3N4CA 2E02A 1MHWA 2FQ9A 3H8BA 3BCNA 2P7UA 3K24A 2PBHA 2AVWA 2JQGR 4YYSA 2VHSA 4X6HA 5CHTA 4I07A 3KWBX 1MEGA 1NL6A 2ARYA 3OVXA 4X6IA 1JQPA 2DCAA 4MZSA 4FIPA 2F7DA 2R9MA 2VHFA 3U8EA 1K3BB 1GCBA 4AXMA 1AYVA 2CB5A 2FT2A 5EF4A 1SP4B 4CDFB 3V6CA 1SNKA 3IV2A 3P5WA 5F02A 3RVWA 4ZUXU 1EWLA 3LXSA 4YVAA 3H89A 3C9EA 4KLBA 1S4VA 3KWZA 3N3GA 2NQGA 1DEUA 4P6GA 1MS6A 2P0RA 3HD3A 2DJGB 1M6DA 5EGWA 1U9QX 3V6EA 2G8EA 5CHVA 2R9CA 2BDZA 2GFOA 2G6DA 2OULA 2AS8A 1CVZA 1ZIVA 3PBHA 3OF9A 9PAPA 4CDDB 3HHAA 2NQIA 1Y4HA 4CDEB 5PADA 3AI8A 1ME4A 1F29A 3BPFA 3MORA 4RY2A 2DCDA 3KFQA 4BS5A 3DF0A 1GMYA 1AU4A 3H8CA 3USVA 3CH3X 3MHSA 3PNRA 1PADA 1YK8A 1ITOA 2PNSA 1POPA 1PBHA 1PE6A 2BDLA 1NPZA 3CBKA 1CJLA 2NQDB 2R9FA 3CH2X 7PCKA 3H6SA 2OZ2A 1O0EA 3P5UA 4PADA 2XU5A 2E00A 1AU3A 1EF7A 2E01A 2AYNA 1FH0A 2YJ8A 1TL9A 1YVBA 2IBIA 3GCBA 4BQVA 1YT7A 3CBJA 3LFYA 4XR7A 4P6EA 1CSBB 4PP2E 3S3RA 2FRQA 2DC7A 3BWKA 3BC3A 1YK7A 1BGOA 2Y5BA 4N8WA 1AU2A 3PW3A 3OVZA 1HUCB 1QOLA 2DJFB 1CV8A 1BQIA 1PPNA 4YYWA 1QXPA 3WXEA 3BPMA 2NQAA 4N79A 2ACTA 3TNXA 1CQDA 3K8UA 3OISA 5K16A 2PADA 4X6JA 4I05A 4BS6A 4CDCB 4W5BA
chains in the Genus database with same CATH superfamily
1TLOA 4MSXA 2AUZA 4BOQA 1AYUA 2B1MA 1GECE 4CZWA 3WXGA 3HHIA 3PSEA 3BY4A 3BOWA 1AU0A 3N3KA 3B79A 4OVZB 4K7CA 3IUTA 2J7QC 2P86A 1KXRA 2GHUA 2FE8A 1U9VA 1KHQA 1EWOA 2AGAA 2ATOA 4YYVA 4BOUA 1TU6A 1ICFA 4BSQA 2XU1A 6PADA 2WBFX 2B1NA 1MIRA 3M99A 3IEJA 4PP1A 1PCIA 4OW0A 1DF0A 2AUXA 1XKGA 3ZUAA 3HWNA 4PT5A 5JZEA 1QDQA 1PPOA 1U9WA 1NB5A 1AIMA 2FRAA 2OP3A 1STFE 2IPPB 4W4UA 4Q8GA 4AXLA 4HWYA 4FJCA 4QRVA 4QBBA 1ZCMA 1KFUL 3MHHA 3OF8A 1MDWA 1Q6KA 2DZZA 1KHPA 4BPVA 2FUDA 2HH5A 3F75A 5CVMA 2CIOA 2HHNA 2G8JA 2FYEA 2DC9A 3MTNA 1CTEA 3IOQA 3I06A 1ME3A 3I3TA 1UKFA 3RVVA 2O6XA 2H7JA 5CVNB 2AIMA 3KSEA 4WA6A 2XU4A 1GLOA 1AECA 2AYOA 5JA7A 4YV8A 4BOZA 2YJ9A 3E1ZB 2AU1A 4IP3A 2BTWB 1BP4A 2FTDA 2R9NA 4OVZA 3QT4A 4QRXA 2YJ2A 3TRKA 5A24A 2R9OA 4MZOA 3O0UA 2Y6EA 1U5IA 2HD5A 5EZSA 4IUMA 3P5VA 1NQCA 3PRPA 1ATKA 4XUIA 3KKUA 1CPJA 2BU3A 4QH6A 3RVXA 3MTVA 3W31A 1EWMA 2DZYA 1PXVA 4OELA 4BOPA 1X9YA 1THEA 4YYUA 8PCHA 3P5XA 4QRGA 5J94A 2YJCA 4PI3A 4BOSA 3PDFA 1A6RA 2E03A 3NHEA 3F5VA 4R3DA 5CVOB 2JQFR 2DC6A 1PPDA 3IHPA 3QSDA 1NLJA 1U9XA 3OQCA 2XU3A 3KW9A 5JH3A 2J7QA 4W5CA 2R6NA 3QJ3A 4DMXA 1QMYA 4MI7A 3ERVA 1NB3A 3IMAA 2C0YA 4YYQA 2HXZA 3KX1A 3D6SA 1BY8A 4I04A 4D8BA 1F2CA 2F1GA 5FPWA 2YJBA 2DCCA 1VJVA 5KO3A 4G54A 3S3QA 1PIPA 1EWPA 4YYRA 1AYWA 1KFXL 3BBAA 3B21A 1YZBA 4DMYA 4D8EA 4Q8HA 1CS8A 3O1GA 2DC8A 3H7DA 2BTWA 2FO5A 4M0WA 3PHXA 2DCBA 1Y08A 1MEMA 5EZQA 1CB5A 1PPPA 4FK5A 4REZA 4OEMA 1VSNA 3K9MA 4N4ZA 2PREA 5E6JA 3WXFA 1F2BA 4HXDB 1F2AA 2G7YA 3MJ5A 1IWDA 1YALA 3N4CA 4MM3B 2E02A 1MHWA 2FQ9A 2Z84A 3H8BA 3BCNA 2P7UA 3K24A 2PBHA 2AVWA 2JQGR 4YYSA 2VHSA 4X6HA 5CHTA 4I07A 3KWBX 1MEGA 1NL6A 2ARYA 3OVXA 4X6IA 1JQPA 2DCAA 3PT2A 3PHUA 4RNAA 4MZSA 4GUAA 4FIPA 2F7DA 2R9MA 2VHFA 3U8EA 1K3BB 4RF1A 1GCBA 4AXMA 1AYVA 2CB5A 2FT2A 5EF4A 1SP4B 4CDFB 3V6CA 1SNKA 3IV2A 3P5WA 4RKXA 4ZTBA 5F02A 3BB7A 3RVWA 4ZUXU 1EWLA 3LXSA 4YVAA 3H89A 3C9EA 4KLBA 1S4VA 3KWZA 3N3GA 3IFUA 2NQGA 1DEUA 4P6GA 2UZJA 1MS6A 2P0RA 3HD3A 2DJGB 4XZXA 1M6DA 5EGWA 4D8IA 1U9QX 3V6EA 3O65A 2G8EA 5CHVA 2R9CA 2BDZA 2GFOA 2G6DA 2OULA 2AS8A 1CVZA 1ZIVA 3PBHA 2JRIA 3OF9A 9PAPA 3ZNHA 3HHAA 4CDDB 2NQIA 1Y4HA 4CDEB 5PADA 3AI8A 1ME4A 1F29A 3BPFA 3MORA 4RY2A 2DCDA 2HWKA 3KFQA 4BS5A 3DF0A 1GMYA 1AU4A 3H8CA 3USVA 3CH3X 3W30A 3MHSA 3PNRA 4P16A 1PADA 1YK8A 1ITOA 2PNSA 1POPA 1PBHA 1PE6A 2DOSA 3RNVA 2BDLA 3C0RA 1NPZA 3CBKA 1PVJA 1CJLA 2NQDB 2R9FA 3CH2X 7PCKA 3H6SA 2OZ2A 1O0EA 3P5UA 4PADA 2XU5A 2E00A 1AU3A 1EF7A 2E01A 2AYNA 1FH0A 2YJ8A 1TL9A 1YVBA 2IBIA 3GCBA 4BQVA 1YT7A 3CBJA 3E9SA 3LFYA 4WURA 4RF0A 4XR7A 4P6EA 1CSBB 4PP2E 3S3RA 2FRQA 2DC7A 3BWKA 2JTCA 3MP2A 3TMPA 3BC3A 1YK7A 1BGOA 2Y5BA 4N8WA 1AU2A 3PW3A 3OVZA 1HUCB 1QOLA 2DJFB 1CV8A 1BQIA 1PPNA 4YYWA 1QXPA 1DKIA 3WXEA 3BPMA 2NQAA 4N79A 3PRMA 2ACTA 3TNXA 1CQDA 3PHWA 4A5UA 3K8UA 3OISA 5K16A 2PADA 4X6JA 4I05A 4BS6A 4CDCB 4W5BA
chains in the Genus database with same CATH topology
1TLOA 4MSXA 2AUZA 1AYUA 2B1MA 1GECE 4CZWA 3WXGA 3HHIA 3BOWA 1AU0A 3N3KA 3B79A 4K7CA 3IUTA 2P86A 1KXRA 2GHUA 1U9VA 1KHQA 1EWOA 2ATOA 4YYVA 1TU6A 1W4TA 1ICFA 4BSQA 2XU1A 6PADA 2WBFX 2B1NA 1MIRA 3M99A 3IEJA 4PP1A 1PCIA 1DF0A 2AUXA 1XKGA 3ZUAA 3HWNA 1QDQA 1PPOA 1U9WA 1NB5A 1AIMA 2FRAA 2OP3A 1STFE 2IPPB 4W4UA 4Q8GA 4AXLA 4BGFA 4HWYA 4FJCA 4QRVA 4QBBA 1ZCMA 1KFUL 3MHHA 3OF8A 1MDWA 3LTWA 1Q6KA 4C5PA 2DZZA 1KHPA 4BPVA 2FUDA 2HH5A 3F75A 5CVMA 2CIOA 2HHNA 2G8JA 2FYEA 2DC9A 3MTNA 1CTEA 3IOQA 3I06A 1ME3A 3I3TA 3RVVA 2O6XA 2H7JA 5CVNB 2AIMA 3KSEA 4WA6A 2XU4A 1GLOA 1AECA 2AYOA 5JA7A 4YV8A 2YJ9A 3E1ZB 2AU1A 1BP4A 2FTDA 2R9NA 3QT4A 4QRXA 2YJ2A 5A24A 2R9OA 4MZOA 3O0UA 2Y6EA 1U5IA 2HD5A 3P5VA 1NQCA 1ATKA 4XUIA 3KKUA 1CPJA 4QH6A 3RVXA 1EWMA 2DZYA 1PXVA 4OELA 1X9YA 1THEA 4YYUA 8PCHA 3P5XA 4QRGA 5J94A 2YJCA 4PI3A 3PDFA 1A6RA 2E03A 3D9WA 3NHEA 3F5VA 4NV8A 5CVOB 2JQFR 2DC6A 1PPDA 3IHPA 3QSDA 1NLJA 1U9XA 2XU3A 3KW9A 5JH3A 4W5CA 2R6NA 3QJ3A 4DMXA 1QMYA 3ERVA 1NB3A 3IMAA 2C0YA 4YYQA 2HXZA 3KX1A 3D6SA 1BY8A 4I04A 4B55A 1F2CA 2F1GA 5FPWA 2YJBA 2DCCA 1VJVA 4G54A 3S3QA 1PIPA 1EWPA 4YYRA 1AYWA 1KFXL 4DMYA 4Q8HA 1CS8A 3O1GA 2DC8A 3H7DA 2FO5A 2DCBA 1Y08A 1MEMA 1CB5A 1PPPA 4FK5A 4OEMA 1VSNA 3K9MA 4N4ZA 2PREA 3WXFA 1F2BA 1F2AA 2G7YA 1IWDA 1YALA 3N4CA 2E02A 1W6FA 1MHWA 2FQ9A 3H8BA 3BCNA 2P7UA 3K24A 4GUZA 2PBHA 2AVWA 2JQGR 4YYSA 2VHSA 4X6HA 5CHTA 4I07A 3KWBX 1MEGA 1NL6A 2ARYA 3OVXA 4X6IA 1JQPA 2DCAA 4MZSA 4FIPA 2F7DA 2R9MA 2VHFA 3U8EA 1K3BB 1GCBA 4AXMA 1AYVA 2CB5A 2FT2A 5EF4A 1SP4B 4CDFB 3V6CA 1SNKA 3IV2A 3P5WA 5F02A 3RVWA 4ZUXU 1EWLA 3LXSA 4YVAA 3H89A 3C9EA 4KLBA 1S4VA 3KWZA 3N3GA 2NQGA 1DEUA 4P6GA 1MS6A 2P0RA 3HD3A 2DJGB 1M6DA 5EGWA 1U9QX 3V6EA 2G8EA 5CHVA 2R9CA 2BDZA 2GFOA 2G6DA 1GX3A 2OULA 2AS8A 1CVZA 1ZIVA 3PBHA 3OF9A 9PAPA 4CDDB 3HHAA 2NQIA 1Y4HA 4CDEB 5PADA 3AI8A 1ME4A 1F29A 3BPFA 3MORA 4RY2A 2DCDA 3KFQA 4BS5A 3DF0A 1GMYA 1AU4A 3H8CA 3USVA 3CH3X 3MHSA 3PNRA 1PADA 1YK8A 1ITOA 2PNSA 1POPA 1PBHA 1PE6A 2BDLA 1NPZA 3CBKA 1CJLA 2NQDB 2R9FA 3CH2X 7PCKA 3H6SA 2VFBA 2OZ2A 1O0EA 3P5UA 4PADA 2XU5A 2E00A 1AU3A 1EF7A 2E01A 2AYNA 1FH0A 2YJ8A 1TL9A 1YVBA 2IBIA 3GCBA 4BQVA 1YT7A 3CBJA 3LFYA 4XR7A 4P6EA 1CSBB 4PP2E 3S3RA 2FRQA 4NV7A 2DC7A 3BWKA 3BC3A 1YK7A 1BGOA 2Y5BA 4N8WA 1AU2A 3PW3A 3OVZA 1HUCB 1QOLA 2DJFB 1CV8A 1BQIA 2BSZA 1PPNA 4YYWA 1E2TA 1QXPA 3WXEA 3BPMA 2NQAA 4N79A 2ACTA 3TNXA 1CQDA 1W5RA 2VFCA 3K8UA 3OISA 5K16A 2PADA 4X6JA 4I05A 4BS6A 4CDCB 4W5BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TLO A;  4MSX A;  2AUZ A;  1AYU A;  2B1M A;  1GEC E;  4CZW A;  3WXG A;  3HHI A;  3BOW A;  1AU0 A;  3N3K A;  3B79 A;  4K7C A;  3IUT A;  2P86 A;  1KXR A;  2GHU A;  1U9V A;  1KHQ A;  1EWO A;  2ATO A;  4YYV A;  1TU6 A;  1ICF A;  4BSQ A;  2XU1 A;  6PAD A;  2WBF X;  2B1N A;  1MIR A;  3M99 A;  3IEJ A;  4PP1 A;  1PCI A;  1DF0 A;  2AUX A;  1XKG A;  3ZUA A;  3HWN A;  1QDQ A;  1PPO A;  1U9W A;  1NB5 A;  1AIM A;  2FRA A;  2OP3 A;  1STF E;  2IPP B;  4W4U A;  4Q8G A;  4AXL A;  4HWY A;  4FJC A;  4QRV A;  4QBB A;  1ZCM A;  1KFU L;  3MHH A;  3OF8 A;  1MDW A;  1Q6K A;  2DZZ A;  1KHP A;  4BPV A;  2FUD A;  2HH5 A;  3F75 A;  5CVM A;  2CIO A;  2HHN A;  2G8J A;  2FYE A;  2DC9 A;  3MTN A;  1CTE A;  3IOQ A;  3I06 A;  1ME3 A;  3I3T A;  3RVV A;  2O6X A;  2H7J A;  5CVN B;  2AIM A;  3KSE A;  4WA6 A;  2XU4 A;  1GLO A;  1AEC A;  2AYO A;  5JA7 A;  4YV8 A;  2YJ9 A;  3E1Z B;  2AU1 A;  1BP4 A;  2FTD A;  2R9N A;  3QT4 A;  4QRX A;  2YJ2 A;  5A24 A;  2R9O A;  4MZO A;  3O0U A;  2Y6E A;  1U5I A;  2HD5 A;  3P5V A;  1NQC A;  1ATK A;  4XUI A;  3KKU A;  1CPJ A;  4QH6 A;  3RVX A;  1EWM A;  2DZY A;  1PXV A;  4OEL A;  1X9Y A;  1THE A;  4YYU A;  8PCH A;  3P5X A;  4QRG A;  5J94 A;  2YJC A;  4PI3 A;  3PDF A;  1A6R A;  2E03 A;  3NHE A;  3F5V A;  5CVO B;  2JQF R;  2DC6 A;  1PPD A;  3IHP A;  3QSD A;  1NLJ A;  1U9X A;  2XU3 A;  3KW9 A;  5JH3 A;  4W5C A;  2R6N A;  3QJ3 A;  4DMX A;  1QMY A;  3ERV A;  1NB3 A;  3IMA A;  2C0Y A;  4YYQ A;  2HXZ A;  3KX1 A;  3D6S A;  1BY8 A;  4I04 A;  1F2C A;  2F1G A;  5FPW A;  2YJB A;  2DCC A;  1VJV A;  4G54 A;  3S3Q A;  1PIP A;  1EWP A;  4YYR A;  1AYW A;  1KFX L;  4DMY A;  4Q8H A;  1CS8 A;  3O1G A;  2DC8 A;  3H7D A;  2FO5 A;  2DCB A;  1Y08 A;  1MEM A;  1CB5 A;  1PPP A;  4FK5 A;  4OEM A;  1VSN A;  3K9M A;  4N4Z A;  2PRE A;  3WXF A;  1F2B A;  1F2A A;  2G7Y A;  1IWD A;  1YAL A;  3N4C A;  2E02 A;  1MHW A;  2FQ9 A;  3H8B A;  3BCN A;  2P7U A;  3K24 A;  2PBH A;  2AVW A;  2JQG R;  4YYS A;  2VHS A;  4X6H A;  5CHT A;  4I07 A;  3KWB X;  1MEG A;  1NL6 A;  2ARY A;  3OVX A;  4X6I A;  1JQP A;  2DCA A;  4MZS A;  4FIP A;  2F7D A;  2R9M A;  2VHF A;  3U8E A;  1K3B B;  1GCB A;  4AXM A;  1AYV A;  2CB5 A;  2FT2 A;  5EF4 A;  1SP4 B;  4CDF B;  3V6C A;  1SNK A;  3IV2 A;  3P5W A;  5F02 A;  3RVW A;  4ZUX U;  1EWL A;  3LXS A;  4YVA A;  3H89 A;  3C9E A;  4KLB A;  1S4V A;  3KWZ A;  3N3G A;  2NQG A;  1DEU A;  4P6G A;  1MS6 A;  2P0R A;  3HD3 A;  2DJG B;  1M6D A;  5EGW A;  1U9Q X;  3V6E A;  2G8E A;  5CHV A;  2R9C A;  2BDZ A;  2GFO A;  2G6D A;  2OUL A;  2AS8 A;  1CVZ A;  1ZIV A;  3PBH A;  3OF9 A;  9PAP A;  4CDD B;  3HHA A;  2NQI A;  1Y4H A;  4CDE B;  5PAD A;  3AI8 A;  1ME4 A;  1F29 A;  3BPF A;  3MOR A;  4RY2 A;  2DCD A;  3KFQ A;  4BS5 A;  3DF0 A;  1GMY A;  1AU4 A;  3H8C A;  3USV A;  3CH3 X;  3MHS A;  3PNR A;  1PAD A;  1YK8 A;  1ITO A;  2PNS A;  1POP A;  1PBH A;  1PE6 A;  2BDL A;  1NPZ A;  3CBK A;  1CJL A;  2NQD B;  2R9F A;  3CH2 X;  7PCK A;  3H6S A;  2OZ2 A;  1O0E A;  3P5U A;  4PAD A;  2XU5 A;  2E00 A;  1AU3 A;  1EF7 A;  2E01 A;  2AYN A;  1FH0 A;  2YJ8 A;  1TL9 A;  1YVB A;  2IBI A;  3GCB A;  4BQV A;  1YT7 A;  3CBJ A;  3LFY A;  4XR7 A;  4P6E A;  1CSB B;  4PP2 E;  3S3R A;  2FRQ A;  2DC7 A;  3BWK A;  3BC3 A;  1YK7 A;  1BGO A;  2Y5B A;  4N8W A;  1AU2 A;  3PW3 A;  3OVZ A;  1HUC B;  1QOL A;  2DJF B;  1CV8 A;  1BQI A;  1PPN A;  4YYW A;  1QXP A;  3WXE A;  3BPM A;  2NQA A;  4N79 A;  2ACT A;  3TNX A;  1CQD A;  3K8U A;  3OIS A;  5K16 A;  2PAD A;  4X6J A;  4I05 A;  4BS6 A;  4CDC B;  4W5B A; 
#chains in the Genus database with same CATH topology
 1TLO A;  4MSX A;  2AUZ A;  4BOQ A;  1AYU A;  2B1M A;  1GEC E;  4CZW A;  3WXG A;  3HHI A;  3PSE A;  3BY4 A;  3BOW A;  1AU0 A;  3N3K A;  3B79 A;  4OVZ B;  4K7C A;  3IUT A;  2J7Q C;  2P86 A;  1KXR A;  2GHU A;  2FE8 A;  1U9V A;  1KHQ A;  1EWO A;  2AGA A;  2ATO A;  4YYV A;  4BOU A;  1TU6 A;  1ICF A;  4BSQ A;  2XU1 A;  6PAD A;  2WBF X;  2B1N A;  1MIR A;  3M99 A;  3IEJ A;  4PP1 A;  1PCI A;  4OW0 A;  1DF0 A;  2AUX A;  1XKG A;  3ZUA A;  3HWN A;  4PT5 A;  5JZE A;  1QDQ A;  1PPO A;  1U9W A;  1NB5 A;  1AIM A;  2FRA A;  2OP3 A;  1STF E;  2IPP B;  4W4U A;  4Q8G A;  4AXL A;  4HWY A;  4FJC A;  4QRV A;  4QBB A;  1ZCM A;  1KFU L;  3MHH A;  3OF8 A;  1MDW A;  1Q6K A;  2DZZ A;  1KHP A;  4BPV A;  2FUD A;  2HH5 A;  3F75 A;  5CVM A;  2CIO A;  2HHN A;  2G8J A;  2FYE A;  2DC9 A;  3MTN A;  1CTE A;  3IOQ A;  3I06 A;  1ME3 A;  3I3T A;  1UKF A;  3RVV A;  2O6X A;  2H7J A;  5CVN B;  2AIM A;  3KSE A;  4WA6 A;  2XU4 A;  1GLO A;  1AEC A;  2AYO A;  5JA7 A;  4YV8 A;  4BOZ A;  2YJ9 A;  3E1Z B;  2AU1 A;  4IP3 A;  2BTW B;  1BP4 A;  2FTD A;  2R9N A;  4OVZ A;  3QT4 A;  4QRX A;  2YJ2 A;  3TRK A;  5A24 A;  2R9O A;  4MZO A;  3O0U A;  2Y6E A;  1U5I A;  2HD5 A;  5EZS A;  4IUM A;  3P5V A;  1NQC A;  3PRP A;  1ATK A;  4XUI A;  3KKU A;  1CPJ A;  2BU3 A;  4QH6 A;  3RVX A;  3MTV A;  3W31 A;  1EWM A;  2DZY A;  1PXV A;  4OEL A;  4BOP A;  1X9Y A;  1THE A;  4YYU A;  8PCH A;  3P5X A;  4QRG A;  5J94 A;  2YJC A;  4PI3 A;  4BOS A;  3PDF A;  1A6R A;  2E03 A;  3NHE A;  3F5V A;  4R3D A;  5CVO B;  2JQF R;  2DC6 A;  1PPD A;  3IHP A;  3QSD A;  1NLJ A;  1U9X A;  3OQC A;  2XU3 A;  3KW9 A;  5JH3 A;  2J7Q A;  4W5C A;  2R6N A;  3QJ3 A;  4DMX A;  1QMY A;  4MI7 A;  3ERV A;  1NB3 A;  3IMA A;  2C0Y A;  4YYQ A;  2HXZ A;  3KX1 A;  3D6S A;  1BY8 A;  4I04 A;  4D8B A;  1F2C A;  2F1G A;  5FPW A;  2YJB A;  2DCC A;  1VJV A;  5KO3 A;  4G54 A;  3S3Q A;  1PIP A;  1EWP A;  4YYR A;  1AYW A;  1KFX L;  3BBA A;  3B21 A;  1YZB A;  4DMY A;  4D8E A;  4Q8H A;  1CS8 A;  3O1G A;  2DC8 A;  3H7D A;  2BTW A;  2FO5 A;  4M0W A;  3PHX A;  2DCB A;  1Y08 A;  1MEM A;  5EZQ A;  1CB5 A;  1PPP A;  4FK5 A;  4REZ A;  4OEM A;  1VSN A;  3K9M A;  4N4Z A;  2PRE A;  5E6J A;  3WXF A;  1F2B A;  4HXD B;  1F2A A;  2G7Y A;  3MJ5 A;  1IWD A;  1YAL A;  3N4C A;  4MM3 B;  2E02 A;  1MHW A;  2FQ9 A;  2Z84 A;  3H8B A;  3BCN A;  2P7U A;  3K24 A;  2PBH A;  2AVW A;  2JQG R;  4YYS A;  2VHS A;  4X6H A;  5CHT A;  4I07 A;  3KWB X;  1MEG A;  1NL6 A;  2ARY A;  3OVX A;  4X6I A;  1JQP A;  2DCA A;  3PT2 A;  3PHU A;  4RNA A;  4MZS A;  4GUA A;  4FIP A;  2F7D A;  2R9M A;  2VHF A;  3U8E A;  1K3B B;  4RF1 A;  1GCB A;  4AXM A;  1AYV A;  2CB5 A;  2FT2 A;  5EF4 A;  1SP4 B;  4CDF B;  3V6C A;  1SNK A;  3IV2 A;  3P5W A;  4RKX A;  4ZTB A;  5F02 A;  3BB7 A;  3RVW A;  4ZUX U;  1EWL A;  3LXS A;  4YVA A;  3H89 A;  3C9E A;  4KLB A;  1S4V A;  3KWZ A;  3N3G A;  3IFU A;  2NQG A;  1DEU A;  4P6G A;  2UZJ A;  1MS6 A;  2P0R A;  3HD3 A;  2DJG B;  4XZX A;  1M6D A;  5EGW A;  4D8I A;  1U9Q X;  3V6E A;  3O65 A;  2G8E A;  5CHV A;  2R9C A;  2BDZ A;  2GFO A;  2G6D A;  2OUL A;  2AS8 A;  1CVZ A;  1ZIV A;  3PBH A;  2JRI A;  3OF9 A;  9PAP A;  3ZNH A;  3HHA A;  4CDD B;  2NQI A;  1Y4H A;  4CDE B;  5PAD A;  3AI8 A;  1ME4 A;  1F29 A;  3BPF A;  3MOR A;  4RY2 A;  2DCD A;  2HWK A;  3KFQ A;  4BS5 A;  3DF0 A;  1GMY A;  1AU4 A;  3H8C A;  3USV A;  3CH3 X;  3W30 A;  3MHS A;  3PNR A;  4P16 A;  1PAD A;  1YK8 A;  1ITO A;  2PNS A;  1POP A;  1PBH A;  1PE6 A;  2DOS A;  3RNV A;  2BDL A;  3C0R A;  1NPZ A;  3CBK A;  1PVJ A;  1CJL A;  2NQD B;  2R9F A;  3CH2 X;  7PCK A;  3H6S A;  2OZ2 A;  1O0E A;  3P5U A;  4PAD A;  2XU5 A;  2E00 A;  1AU3 A;  1EF7 A;  2E01 A;  2AYN A;  1FH0 A;  2YJ8 A;  1TL9 A;  1YVB A;  2IBI A;  3GCB A;  4BQV A;  1YT7 A;  3CBJ A;  3E9S A;  3LFY A;  4WUR A;  4RF0 A;  4XR7 A;  4P6E A;  1CSB B;  4PP2 E;  3S3R A;  2FRQ A;  2DC7 A;  3BWK A;  2JTC A;  3MP2 A;  3TMP A;  3BC3 A;  1YK7 A;  1BGO A;  2Y5B A;  4N8W A;  1AU2 A;  3PW3 A;  3OVZ A;  1HUC B;  1QOL A;  2DJF B;  1CV8 A;  1BQI A;  1PPN A;  4YYW A;  1QXP A;  1DKI A;  3WXE A;  3BPM A;  2NQA A;  4N79 A;  3PRM A;  2ACT A;  3TNX A;  1CQD A;  3PHW A;  4A5U A;  3K8U A;  3OIS A;  5K16 A;  2PAD A;  4X6J A;  4I05 A;  4BS6 A;  4CDC B;  4W5B A; 
#chains in the Genus database with same CATH homology
 1TLO A;  4MSX A;  2AUZ A;  1AYU A;  2B1M A;  1GEC E;  4CZW A;  3WXG A;  3HHI A;  3BOW A;  1AU0 A;  3N3K A;  3B79 A;  4K7C A;  3IUT A;  2P86 A;  1KXR A;  2GHU A;  1U9V A;  1KHQ A;  1EWO A;  2ATO A;  4YYV A;  1TU6 A;  1W4T A;  1ICF A;  4BSQ A;  2XU1 A;  6PAD A;  2WBF X;  2B1N A;  1MIR A;  3M99 A;  3IEJ A;  4PP1 A;  1PCI A;  1DF0 A;  2AUX A;  1XKG A;  3ZUA A;  3HWN A;  1QDQ A;  1PPO A;  1U9W A;  1NB5 A;  1AIM A;  2FRA A;  2OP3 A;  1STF E;  2IPP B;  4W4U A;  4Q8G A;  4AXL A;  4BGF A;  4HWY A;  4FJC A;  4QRV A;  4QBB A;  1ZCM A;  1KFU L;  3MHH A;  3OF8 A;  1MDW A;  3LTW A;  1Q6K A;  4C5P A;  2DZZ A;  1KHP A;  4BPV A;  2FUD A;  2HH5 A;  3F75 A;  5CVM A;  2CIO A;  2HHN A;  2G8J A;  2FYE A;  2DC9 A;  3MTN A;  1CTE A;  3IOQ A;  3I06 A;  1ME3 A;  3I3T A;  3RVV A;  2O6X A;  2H7J A;  5CVN B;  2AIM A;  3KSE A;  4WA6 A;  2XU4 A;  1GLO A;  1AEC A;  2AYO A;  5JA7 A;  4YV8 A;  2YJ9 A;  3E1Z B;  2AU1 A;  1BP4 A;  2FTD A;  2R9N A;  3QT4 A;  4QRX A;  2YJ2 A;  5A24 A;  2R9O A;  4MZO A;  3O0U A;  2Y6E A;  1U5I A;  2HD5 A;  3P5V A;  1NQC A;  1ATK A;  4XUI A;  3KKU A;  1CPJ A;  4QH6 A;  3RVX A;  1EWM A;  2DZY A;  1PXV A;  4OEL A;  1X9Y A;  1THE A;  4YYU A;  8PCH A;  3P5X A;  4QRG A;  5J94 A;  2YJC A;  4PI3 A;  3PDF A;  1A6R A;  2E03 A;  3D9W A;  3NHE A;  3F5V A;  4NV8 A;  5CVO B;  2JQF R;  2DC6 A;  1PPD A;  3IHP A;  3QSD A;  1NLJ A;  1U9X A;  2XU3 A;  3KW9 A;  5JH3 A;  4W5C A;  2R6N A;  3QJ3 A;  4DMX A;  1QMY A;  3ERV A;  1NB3 A;  3IMA A;  2C0Y A;  4YYQ A;  2HXZ A;  3KX1 A;  3D6S A;  1BY8 A;  4I04 A;  4B55 A;  1F2C A;  2F1G A;  5FPW A;  2YJB A;  2DCC A;  1VJV A;  4G54 A;  3S3Q A;  1PIP A;  1EWP A;  4YYR A;  1AYW A;  1KFX L;  4DMY A;  4Q8H A;  1CS8 A;  3O1G A;  2DC8 A;  3H7D A;  2FO5 A;  2DCB A;  1Y08 A;  1MEM A;  1CB5 A;  1PPP A;  4FK5 A;  4OEM A;  1VSN A;  3K9M A;  4N4Z A;  2PRE A;  3WXF A;  1F2B A;  1F2A A;  2G7Y A;  1IWD A;  1YAL A;  3N4C A;  2E02 A;  1W6F A;  1MHW A;  2FQ9 A;  3H8B A;  3BCN A;  2P7U A;  3K24 A;  4GUZ A;  2PBH A;  2AVW A;  2JQG R;  4YYS A;  2VHS A;  4X6H A;  5CHT A;  4I07 A;  3KWB X;  1MEG A;  1NL6 A;  2ARY A;  3OVX A;  4X6I A;  1JQP A;  2DCA A;  4MZS A;  4FIP A;  2F7D A;  2R9M A;  2VHF A;  3U8E A;  1K3B B;  1GCB A;  4AXM A;  1AYV A;  2CB5 A;  2FT2 A;  5EF4 A;  1SP4 B;  4CDF B;  3V6C A;  1SNK A;  3IV2 A;  3P5W A;  5F02 A;  3RVW A;  4ZUX U;  1EWL A;  3LXS A;  4YVA A;  3H89 A;  3C9E A;  4KLB A;  1S4V A;  3KWZ A;  3N3G A;  2NQG A;  1DEU A;  4P6G A;  1MS6 A;  2P0R A;  3HD3 A;  2DJG B;  1M6D A;  5EGW A;  1U9Q X;  3V6E A;  2G8E A;  5CHV A;  2R9C A;  2BDZ A;  2GFO A;  2G6D A;  1GX3 A;  2OUL A;  2AS8 A;  1CVZ A;  1ZIV A;  3PBH A;  3OF9 A;  9PAP A;  4CDD B;  3HHA A;  2NQI A;  1Y4H A;  4CDE B;  5PAD A;  3AI8 A;  1ME4 A;  1F29 A;  3BPF A;  3MOR A;  4RY2 A;  2DCD A;  3KFQ A;  4BS5 A;  3DF0 A;  1GMY A;  1AU4 A;  3H8C A;  3USV A;  3CH3 X;  3MHS A;  3PNR A;  1PAD A;  1YK8 A;  1ITO A;  2PNS A;  1POP A;  1PBH A;  1PE6 A;  2BDL A;  1NPZ A;  3CBK A;  1CJL A;  2NQD B;  2R9F A;  3CH2 X;  7PCK A;  3H6S A;  2VFB A;  2OZ2 A;  1O0E A;  3P5U A;  4PAD A;  2XU5 A;  2E00 A;  1AU3 A;  1EF7 A;  2E01 A;  2AYN A;  1FH0 A;  2YJ8 A;  1TL9 A;  1YVB A;  2IBI A;  3GCB A;  4BQV A;  1YT7 A;  3CBJ A;  3LFY A;  4XR7 A;  4P6E A;  1CSB B;  4PP2 E;  3S3R A;  2FRQ A;  4NV7 A;  2DC7 A;  3BWK A;  3BC3 A;  1YK7 A;  1BGO A;  2Y5B A;  4N8W A;  1AU2 A;  3PW3 A;  3OVZ A;  1HUC B;  1QOL A;  2DJF B;  1CV8 A;  1BQI A;  2BSZ A;  1PPN A;  4YYW A;  1E2T A;  1QXP A;  3WXE A;  3BPM A;  2NQA A;  4N79 A;  2ACT A;  3TNX A;  1CQD A;  1W5R A;  2VFC A;  3K8U A;  3OIS A;  5K16 A;  2PAD A;  4X6J A;  4I05 A;  4BS6 A;  4CDC B;  4W5B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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