1AU3A

Crystal structure of the cysteine protease human cathepsin k in complex with a covalent pyrrolidinone inhibitor
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
215
structure length
215
Chain Sequence
APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformationally constrained 1,3-diamino ketones: a series of potent inhibitors of the cysteine protease cathepsin K.
pubmed doi rcsb
molecule keywords CATHEPSIN K
molecule tags Hydrolase
source organism Homo sapiens
total genus 60
structure length 215
sequence length 215
ec nomenclature ec 3.4.22.38: Cathepsin K.
pdb deposition date 1997-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1au3A00
2C0YA 3B79A 1DEUA 3CH2X 3IHPA 2H7JA 2VHSA 3RVXA 4N79A 2FRAA 1MEMA 1U9WA 3RVVA 1YALA 2YJCA 4CDEB 3U8EA 2R9FA 4CZWA 2NQAA 4DMXA 2PREA 1GCBA 1YT7A 2DCCA 3K24A 2XU3A 1ZIVA 3IOQA 1BY8A 1MEGA 4I04A 1QMYA 1QOLA 4I05A 5CVNB 1QDQA 1KFXL 4FIPA 1PXVA 4OEMA 4CDFB 4MZOA 4HWYA 1YK8A 1XKGA 4YYUA 3QSDA 3KKUA 2Y5BA 2PNSA 3ZUAA 4FJCA 5EGWA 3OISA 3H89A 1BP4A 3N4CA 5CVMA 2O6XA 3KSEA 4ZUXU 3HWNA 3E1ZB 3KFQA 4QRGA 2GHUA 2AIMA 1Q6KA 2BDZA 3QJ3A 3MTNA 4P6GA 2JQFR 1S4VA 3CH3X 2R9MA 4X6JA 2OP3A 1U9VA 3K8UA 4W5BA 3USVA 1K3BB 2XU4A 2AU1A 4PP2E 2DCDA 3P5XA 4XUIA 4YV8A 2G7YA 4G54A 2P0RA 3PDFA 1AYVA 3I3TA 2E02A 5K16A 3HHIA 1EWOA 2OZ2A 3LXSA 3OVXA 1EWPA 2VHFA 4K7CA 1U5IA 2E01A 2P7UA 3LFYA 1CPJA 5CHTA 1TL9A 3F75A 2GFOA 4CDDB 4KLBA 5EF4A 3MHSA 4X6HA 1ME4A 1STFE 1NB3A 3HD3A 1NLJA 1PE6A 2IBIA 4W4UA 1KHPA 2FT2A 1NB5A 3F5VA 3V6EA 4CDCB 1SNKA 5CVOB 1ME3A 4N8WA 1HUCB 4MSXA 1ZCMA 2OULA 4RY2A 2PBHA 2IPPB 2NQIA 1MIRA 1KFUL 3KX1A 4QH6A 4YYRA 2HXZA 2HHNA 3DF0A 2G6DA 1PCIA 3IEJA 1VJVA 1AU2A 1BGOA 5F02A 4BSQA 2G8EA 1PPNA 2DCAA 4YYWA 2YJ8A 1Y4HA 2DC6A 1PPDA 2NQGA 2B1NA 2DZYA 3CBJA 1PBHA 4FK5A 5PADA 2CIOA 3P5UA 1CQDA 2FUDA 2DJGB 2DC8A 2Y6EA 2AYNA 2ATOA 2CB5A 3PBHA 4DMYA 1GLOA 4WA6A 4PADA 3CBKA 1O0EA 2FRQA 8PCHA 2F7DA 3PW3A 2PADA 1CVZA 1ATKA 1M6DA 2AYOA 1ICFA 2YJ9A 2YJ2A 2HH5A 1AU3A 5J94A 3D6SA 4Q8HA 1YK7A 3M99A 4YYSA 3PNRA 2G8JA 3S3RA 3S3QA 1AYWA 4QRVA 9PAPA 1THEA 1F2BA 1Y08A 4MZSA 1CS8A 2FTDA 5FPWA 1MHWA 3OF8A 2AVWA 3AI8A 3H7DA 5CHVA 4QRXA 3KWZA 2R9CA 5JA7A 4BS5A 2F1GA 2FQ9A 3OVZA 3RVWA 7PCKA 2R6NA 4Q8GA 2ACTA 1BQIA 3V6CA 4AXLA 4N4ZA 3O0UA 2JQGR 3KWBX 4I07A 1U9XA 4XR7A 3IV2A 1CJLA 2AUZA 4YYVA 3NHEA 1VSNA 3P5VA 2YJBA 1AYUA 5JH3A 3WXGA 1NL6A 2E03A 1TU6A 1KHQA 3BPFA 3IUTA 2HD5A 3MORA 2FYEA 1AU4A 1MDWA 3N3KA 1CTEA 1F29A 1SP4B 2R9OA 1EWMA 6PADA 3BC3A 4AXMA 4OELA 3H6SA 2P86A 1AIMA 3TNXA 4BPVA 3IMAA 1PIPA 2DCBA 2FO5A 1GMYA 3ERVA 3P5WA 1QXPA 1CSBB 2DZZA 3H8CA 2AUXA 2XU5A 3QT4A 3O1GA 3I06A 3K9MA 4QBBA 1PPPA 1FH0A 1DF0A 2AS8A 2NQDB 3WXFA 1X9YA 1YVBA 4PP1A 3H8BA 1JQPA 1F2AA 3MHHA 3GCBA 1IWDA 3WXEA 2E00A 2DC9A 3BCNA 3N3GA 1AU0A 1PPOA 2DJFB 4PI3A 1NPZA 5A24A 1CV8A 2BDLA 2R9NA 3BOWA 4BS6A 3KW9A 1TLOA 1KXRA 2XU1A 1CB5A 3BPMA 1F2CA 1GECE 2B1MA 2ARYA 1A6RA 4YYQA 1POPA 4BQVA 1NQCA 2DC7A 3C9EA 3HHAA 4YVAA 4W5CA 1AECA 1MS6A 1ITOA 3OF9A 3BWKA 1PADA 1U9QX 1EF7A 1EWLA 4X6IA 2WBFX 4P6EA
chains in the Genus database with same CATH superfamily
2C0YA 3B79A 1DEUA 3CH2X 4BOZA 3IHPA 2H7JA 2VHSA 3RVXA 3PT2A 4N79A 4BOQA 2FRAA 1MEMA 1U9WA 3RVVA 3W30A 1YALA 2YJCA 3OQCA 4CDEB 3U8EA 2R9FA 4CZWA 2NQAA 4DMXA 2PREA 1GCBA 1YT7A 2DCCA 3K24A 2XU3A 1ZIVA 3IOQA 1BY8A 1MEGA 4I04A 1QMYA 1QOLA 4I05A 5CVNB 1QDQA 1KFXL 4FIPA 1PXVA 4OEMA 4OVZB 4CDFB 4MZOA 4HWYA 1YK8A 3RNVA 1XKGA 4YYUA 3QSDA 3KKUA 2Z84A 2Y5BA 2PNSA 3ZUAA 1YZBA 4FJCA 5EGWA 3OISA 3H89A 1BP4A 3N4CA 5CVMA 2O6XA 3KSEA 4ZUXU 4OW0A 3HWNA 3E1ZB 4P16A 3KFQA 4QRGA 4RF0A 2GHUA 2AIMA 3PHWA 1Q6KA 2BDZA 3QJ3A 4GUAA 3MTNA 4P6GA 2JQFR 1S4VA 3CH3X 2R9MA 2UZJA 4X6JA 2OP3A 1U9VA 3K8UA 4W5BA 3USVA 1K3BB 2XU4A 2AU1A 4PP2E 2DCDA 3P5XA 4XUIA 4YV8A 2G7YA 4G54A 2P0RA 3PDFA 3BY4A 1AYVA 3I3TA 2E02A 5K16A 3HHIA 1EWOA 2OZ2A 3LXSA 3OVXA 1EWPA 2VHFA 4K7CA 3TMPA 1U5IA 2E01A 4REZA 2P7UA 2BTWA 3LFYA 1CPJA 5CHTA 1TL9A 3ZNHA 3F75A 2GFOA 4CDDB 4KLBA 5EF4A 3MHSA 3PRPA 4X6HA 2AGAA 1ME4A 1STFE 1DKIA 1NB3A 3HD3A 1NLJA 1PE6A 2IBIA 4W4UA 1KHPA 2FT2A 1NB5A 3F5VA 3V6EA 4CDCB 1SNKA 4XZXA 5CVOB 1ME3A 4N8WA 1HUCB 2DOSA 3C0RA 4MSXA 1ZCMA 2OULA 4RY2A 3TRKA 2PBHA 2IPPB 2NQIA 1MIRA 1KFUL 3KX1A 4QH6A 4YYRA 2HXZA 2HHNA 3DF0A 2G6DA 1PCIA 3IEJA 4IUMA 2J7QA 4IP3A 1VJVA 1AU2A 4ZTBA 1BGOA 5F02A 4BSQA 2G8EA 1PPNA 2DCAA 4YYWA 2YJ8A 1Y4HA 2DC6A 5EZQA 1PPDA 2NQGA 2B1NA 2DZYA 3CBJA 1PBHA 3PSEA 4FK5A 5PADA 2CIOA 3P5UA 1CQDA 2FUDA 2DJGB 2DC8A 2Y6EA 5EZSA 2AYNA 2ATOA 5KO3A 2CB5A 3PBHA 5JZEA 4DMYA 1GLOA 4WA6A 4WURA 4PADA 3CBKA 1O0EA 2FRQA 8PCHA 2F7DA 3PW3A 2PADA 1CVZA 1ATKA 1M6DA 2AYOA 1ICFA 2YJ9A 2YJ2A 2HH5A 2BTWB 1AU3A 5J94A 3D6SA 4Q8HA 1YK7A 3M99A 4M0WA 4YYSA 3PNRA 2G8JA 2JTCA 3S3RA 4RKXA 3S3QA 1AYWA 4QRVA 9PAPA 3MJ5A 1THEA 1F2BA 1Y08A 4MZSA 1CS8A 2FTDA 5FPWA 1MHWA 4HXDB 3OF8A 2AVWA 3E9SA 3AI8A 3H7DA 5CHVA 4QRXA 3KWZA 2R9CA 5JA7A 4D8BA 3B21A 3PHXA 2F1GA 2FQ9A 3OVZA 4MI7A 3RVWA 4BS5A 7PCKA 2R6NA 4MM3B 2BU3A 4Q8GA 2ACTA 1BQIA 3BB7A 3V6CA 4AXLA 4N4ZA 4A5UA 3O0UA 2JQGR 3KWBX 4PT5A 4I07A 1U9XA 3BBAA 4XR7A 3IV2A 1CJLA 2AUZA 4YYVA 2HWKA 3PHUA 4BOSA 3NHEA 1VSNA 3P5VA 2YJBA 1AYUA 5JH3A 3WXGA 3IFUA 1NL6A 2E03A 1TU6A 4D8IA 1KHQA 3BPFA 3IUTA 2HD5A 3MORA 2FYEA 1AU4A 1MDWA 3PRMA 3N3KA 1CTEA 1F29A 1SP4B 2R9OA 1EWMA 6PADA 3BC3A 3MP2A 4AXMA 4OELA 3H6SA 3O65A 2P86A 1AIMA 3TNXA 4BPVA 3IMAA 1PIPA 2DCBA 2FO5A 1GMYA 3ERVA 3MTVA 1UKFA 4D8EA 3P5WA 1QXPA 1CSBB 2DZZA 3H8CA 2AUXA 2XU5A 3QT4A 3W31A 3O1GA 4BOPA 3I06A 3K9MA 4QBBA 1PPPA 1FH0A 1DF0A 2AS8A 4OVZA 2NQDB 4RF1A 1X9YA 3WXFA 4BOUA 1YVBA 4PP1A 3H8BA 1JQPA 1F2AA 3MHHA 3GCBA 1IWDA 2J7QC 3WXEA 4RNAA 2E00A 2DC9A 3BCNA 3N3GA 1AU0A 1PPOA 2DJFB 4PI3A 1NPZA 5A24A 1CV8A 2BDLA 2R9NA 3BOWA 4BS6A 3KW9A 2JRIA 1TLOA 1KXRA 2XU1A 1CB5A 3BPMA 1F2CA 1GECE 2B1MA 2ARYA 1A6RA 4YYQA 1POPA 4BQVA 1NQCA 2DC7A 1PVJA 3C9EA 3HHAA 4YVAA 4R3DA 4W5CA 1AECA 2FE8A 1MS6A 1ITOA 3OF9A 3BWKA 5E6JA 1PADA 1U9QX 1EF7A 1EWLA 4X6IA 2WBFX 4P6EA
chains in the Genus database with same CATH topology
2C0YA 3B79A 1DEUA 3CH2X 3IHPA 2H7JA 2VHSA 3RVXA 4N79A 4B55A 2FRAA 1MEMA 1U9WA 3RVVA 1YALA 2YJCA 4CDEB 3U8EA 2R9FA 4CZWA 2NQAA 4DMXA 2PREA 1GCBA 1YT7A 2DCCA 3K24A 2XU3A 1GX3A 2BSZA 1ZIVA 3IOQA 1BY8A 1MEGA 4I04A 1QMYA 1QOLA 4I05A 5CVNB 1QDQA 1KFXL 4FIPA 1PXVA 1W4TA 4OEMA 4CDFB 4MZOA 4HWYA 1YK8A 1XKGA 4YYUA 3QSDA 3KKUA 2Y5BA 2PNSA 3ZUAA 4FJCA 5EGWA 3OISA 3H89A 1BP4A 3N4CA 5CVMA 2O6XA 3KSEA 4ZUXU 3HWNA 3E1ZB 3KFQA 4QRGA 2GHUA 2AIMA 1E2TA 1Q6KA 2BDZA 3QJ3A 3MTNA 4P6GA 2JQFR 1S4VA 3CH3X 2R9MA 4X6JA 2OP3A 1U9VA 3K8UA 4W5BA 3USVA 1K3BB 2XU4A 2AU1A 4PP2E 2DCDA 3P5XA 4XUIA 4YV8A 2G7YA 4G54A 2P0RA 3PDFA 1AYVA 3I3TA 2E02A 5K16A 3HHIA 1EWOA 2OZ2A 1W6FA 3LXSA 1EWPA 3OVXA 2VHFA 4K7CA 1U5IA 2E01A 2P7UA 3LFYA 1CPJA 5CHTA 1TL9A 3F75A 2GFOA 4CDDB 4KLBA 5EF4A 3MHSA 2VFBA 4X6HA 1ME4A 1STFE 1NB3A 3HD3A 1NLJA 1PE6A 2IBIA 4W4UA 1KHPA 2FT2A 1NB5A 3F5VA 3V6EA 4CDCB 1SNKA 5CVOB 1ME3A 4N8WA 1HUCB 4MSXA 1ZCMA 2OULA 4RY2A 2PBHA 2IPPB 2NQIA 1MIRA 1KFUL 3KX1A 4QH6A 4YYRA 2HXZA 2HHNA 3DF0A 2G6DA 1PCIA 3IEJA 1VJVA 1AU2A 1BGOA 5F02A 4BSQA 2G8EA 1PPNA 2DCAA 4YYWA 2YJ8A 1Y4HA 2DC6A 1PPDA 2NQGA 2B1NA 2DZYA 3CBJA 1PBHA 4FK5A 5PADA 2CIOA 3P5UA 1CQDA 2FUDA 2DJGB 4GUZA 2DC8A 3LTWA 2Y6EA 2AYNA 2ATOA 2CB5A 3PBHA 4DMYA 1GLOA 4WA6A 4PADA 3CBKA 1O0EA 2FRQA 8PCHA 2VFCA 4C5PA 2F7DA 3PW3A 2PADA 1CVZA 1ATKA 4NV7A 1W5RA 1M6DA 2AYOA 1ICFA 2YJ9A 2YJ2A 2HH5A 1AU3A 5J94A 3D6SA 4Q8HA 1YK7A 3M99A 4YYSA 3PNRA 2G8JA 3S3RA 3S3QA 1AYWA 4QRVA 9PAPA 1THEA 1F2BA 1Y08A 4MZSA 1CS8A 2FTDA 5FPWA 1MHWA 3OF8A 2AVWA 3AI8A 3H7DA 5CHVA 4QRXA 3KWZA 2R9CA 5JA7A 4BS5A 2F1GA 2FQ9A 3OVZA 3RVWA 7PCKA 2R6NA 4Q8GA 2ACTA 1BQIA 3V6CA 4AXLA 4N4ZA 3O0UA 2JQGR 3KWBX 4I07A 1U9XA 4XR7A 3IV2A 1CJLA 2AUZA 4YYVA 3NHEA 1VSNA 3P5VA 2YJBA 1AYUA 5JH3A 3WXGA 1NL6A 2E03A 1TU6A 1KHQA 3BPFA 3IUTA 2HD5A 3MORA 2FYEA 1AU4A 1MDWA 3N3KA 1CTEA 1F29A 1SP4B 2R9OA 1EWMA 6PADA 3BC3A 4AXMA 4OELA 3H6SA 2P86A 1AIMA 3TNXA 4BGFA 4BPVA 3IMAA 1PIPA 3D9WA 2DCBA 2FO5A 1GMYA 3ERVA 4NV8A 3P5WA 1QXPA 1CSBB 2DZZA 3H8CA 2AUXA 2XU5A 3QT4A 3O1GA 3I06A 3K9MA 4QBBA 1PPPA 1FH0A 1DF0A 2AS8A 2NQDB 3WXFA 1X9YA 1YVBA 4PP1A 3H8BA 1JQPA 1F2AA 3MHHA 3GCBA 1IWDA 3WXEA 2E00A 2DC9A 3BCNA 3N3GA 1AU0A 1PPOA 2DJFB 4PI3A 1NPZA 5A24A 1CV8A 2BDLA 2R9NA 3BOWA 4BS6A 3KW9A 1TLOA 1KXRA 2XU1A 1CB5A 3BPMA 1F2CA 1GECE 2B1MA 2ARYA 1A6RA 4YYQA 1POPA 4BQVA 1NQCA 2DC7A 3C9EA 3HHAA 4YVAA 4W5CA 1AECA 1MS6A 1ITOA 3OF9A 3BWKA 1PADA 1U9QX 1EF7A 1EWLA 4X6IA 2WBFX 4P6EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2C0Y A;  3B79 A;  1DEU A;  3CH2 X;  3IHP A;  2H7J A;  2VHS A;  3RVX A;  4N79 A;  2FRA A;  1MEM A;  1U9W A;  3RVV A;  1YAL A;  2YJC A;  4CDE B;  3U8E A;  2R9F A;  4CZW A;  2NQA A;  4DMX A;  2PRE A;  1GCB A;  1YT7 A;  2DCC A;  3K24 A;  2XU3 A;  1ZIV A;  3IOQ A;  1BY8 A;  1MEG A;  4I04 A;  1QMY A;  1QOL A;  4I05 A;  5CVN B;  1QDQ A;  1KFX L;  4FIP A;  1PXV A;  4OEM A;  4CDF B;  4MZO A;  4HWY A;  1YK8 A;  1XKG A;  4YYU A;  3QSD A;  3KKU A;  2Y5B A;  2PNS A;  3ZUA A;  4FJC A;  5EGW A;  3OIS A;  3H89 A;  1BP4 A;  3N4C A;  5CVM A;  2O6X A;  3KSE A;  4ZUX U;  3HWN A;  3E1Z B;  3KFQ A;  4QRG A;  2GHU A;  2AIM A;  1Q6K A;  2BDZ A;  3QJ3 A;  3MTN A;  4P6G A;  2JQF R;  1S4V A;  3CH3 X;  2R9M A;  4X6J A;  2OP3 A;  1U9V A;  3K8U A;  4W5B A;  3USV A;  1K3B B;  2XU4 A;  2AU1 A;  4PP2 E;  2DCD A;  3P5X A;  4XUI A;  4YV8 A;  2G7Y A;  4G54 A;  2P0R A;  3PDF A;  1AYV A;  3I3T A;  2E02 A;  5K16 A;  3HHI A;  1EWO A;  2OZ2 A;  3LXS A;  3OVX A;  1EWP A;  2VHF A;  4K7C A;  1U5I A;  2E01 A;  2P7U A;  3LFY A;  1CPJ A;  5CHT A;  1TL9 A;  3F75 A;  2GFO A;  4CDD B;  4KLB A;  5EF4 A;  3MHS A;  4X6H A;  1ME4 A;  1STF E;  1NB3 A;  3HD3 A;  1NLJ A;  1PE6 A;  2IBI A;  4W4U A;  1KHP A;  2FT2 A;  1NB5 A;  3F5V A;  3V6E A;  4CDC B;  1SNK A;  5CVO B;  1ME3 A;  4N8W A;  1HUC B;  4MSX A;  1ZCM A;  2OUL A;  4RY2 A;  2PBH A;  2IPP B;  2NQI A;  1MIR A;  1KFU L;  3KX1 A;  4QH6 A;  4YYR A;  2HXZ A;  2HHN A;  3DF0 A;  2G6D A;  1PCI A;  3IEJ A;  1VJV A;  1AU2 A;  1BGO A;  5F02 A;  4BSQ A;  2G8E A;  1PPN A;  2DCA A;  4YYW A;  2YJ8 A;  1Y4H A;  2DC6 A;  1PPD A;  2NQG A;  2B1N A;  2DZY A;  3CBJ A;  1PBH A;  4FK5 A;  5PAD A;  2CIO A;  3P5U A;  1CQD A;  2FUD A;  2DJG B;  2DC8 A;  2Y6E A;  2AYN A;  2ATO A;  2CB5 A;  3PBH A;  4DMY A;  1GLO A;  4WA6 A;  4PAD A;  3CBK A;  1O0E A;  2FRQ A;  8PCH A;  2F7D A;  3PW3 A;  2PAD A;  1CVZ A;  1ATK A;  1M6D A;  2AYO A;  1ICF A;  2YJ9 A;  2YJ2 A;  2HH5 A;  1AU3 A;  5J94 A;  3D6S A;  4Q8H A;  1YK7 A;  3M99 A;  4YYS A;  3PNR A;  2G8J A;  3S3R A;  3S3Q A;  1AYW A;  4QRV A;  9PAP A;  1THE A;  1F2B A;  1Y08 A;  4MZS A;  1CS8 A;  2FTD A;  5FPW A;  1MHW A;  3OF8 A;  2AVW A;  3AI8 A;  3H7D A;  5CHV A;  4QRX A;  3KWZ A;  2R9C A;  5JA7 A;  4BS5 A;  2F1G A;  2FQ9 A;  3OVZ A;  3RVW A;  7PCK A;  2R6N A;  4Q8G A;  2ACT A;  1BQI A;  3V6C A;  4AXL A;  4N4Z A;  3O0U A;  2JQG R;  3KWB X;  4I07 A;  1U9X A;  4XR7 A;  3IV2 A;  1CJL A;  2AUZ A;  4YYV A;  3NHE A;  1VSN A;  3P5V A;  2YJB A;  1AYU A;  5JH3 A;  3WXG A;  1NL6 A;  2E03 A;  1TU6 A;  1KHQ A;  3BPF A;  3IUT A;  2HD5 A;  3MOR A;  2FYE A;  1AU4 A;  1MDW A;  3N3K A;  1CTE A;  1F29 A;  1SP4 B;  2R9O A;  1EWM A;  6PAD A;  3BC3 A;  4AXM A;  4OEL A;  3H6S A;  2P86 A;  1AIM A;  3TNX A;  4BPV A;  3IMA A;  1PIP A;  2DCB A;  2FO5 A;  1GMY A;  3ERV A;  3P5W A;  1QXP A;  1CSB B;  2DZZ A;  3H8C A;  2AUX A;  2XU5 A;  3QT4 A;  3O1G A;  3I06 A;  3K9M A;  4QBB A;  1PPP A;  1FH0 A;  1DF0 A;  2AS8 A;  2NQD B;  3WXF A;  1X9Y A;  1YVB A;  4PP1 A;  3H8B A;  1JQP A;  1F2A A;  3MHH A;  3GCB A;  1IWD A;  3WXE A;  2E00 A;  2DC9 A;  3BCN A;  3N3G A;  1AU0 A;  1PPO A;  2DJF B;  4PI3 A;  1NPZ A;  5A24 A;  1CV8 A;  2BDL A;  2R9N A;  3BOW A;  4BS6 A;  3KW9 A;  1TLO A;  1KXR A;  2XU1 A;  1CB5 A;  3BPM A;  1F2C A;  1GEC E;  2B1M A;  2ARY A;  1A6R A;  4YYQ A;  1POP A;  4BQV A;  1NQC A;  2DC7 A;  3C9E A;  3HHA A;  4YVA A;  4W5C A;  1AEC A;  1MS6 A;  1ITO A;  3OF9 A;  3BWK A;  1PAD A;  1U9Q X;  1EF7 A;  1EWL A;  4X6I A;  2WBF X;  4P6E A; 
#chains in the Genus database with same CATH topology
 2C0Y A;  3B79 A;  1DEU A;  3CH2 X;  4BOZ A;  3IHP A;  2H7J A;  2VHS A;  3RVX A;  3PT2 A;  4N79 A;  4BOQ A;  2FRA A;  1MEM A;  1U9W A;  3RVV A;  3W30 A;  1YAL A;  2YJC A;  3OQC A;  4CDE B;  3U8E A;  2R9F A;  4CZW A;  2NQA A;  4DMX A;  2PRE A;  1GCB A;  1YT7 A;  2DCC A;  3K24 A;  2XU3 A;  1ZIV A;  3IOQ A;  1BY8 A;  1MEG A;  4I04 A;  1QMY A;  1QOL A;  4I05 A;  5CVN B;  1QDQ A;  1KFX L;  4FIP A;  1PXV A;  4OEM A;  4OVZ B;  4CDF B;  4MZO A;  4HWY A;  1YK8 A;  3RNV A;  1XKG A;  4YYU A;  3QSD A;  3KKU A;  2Z84 A;  2Y5B A;  2PNS A;  3ZUA A;  1YZB A;  4FJC A;  5EGW A;  3OIS A;  3H89 A;  1BP4 A;  3N4C A;  5CVM A;  2O6X A;  3KSE A;  4ZUX U;  4OW0 A;  3HWN A;  3E1Z B;  4P16 A;  3KFQ A;  4QRG A;  4RF0 A;  2GHU A;  2AIM A;  3PHW A;  1Q6K A;  2BDZ A;  3QJ3 A;  4GUA A;  3MTN A;  4P6G A;  2JQF R;  1S4V A;  3CH3 X;  2R9M A;  2UZJ A;  4X6J A;  2OP3 A;  1U9V A;  3K8U A;  4W5B A;  3USV A;  1K3B B;  2XU4 A;  2AU1 A;  4PP2 E;  2DCD A;  3P5X A;  4XUI A;  4YV8 A;  2G7Y A;  4G54 A;  2P0R A;  3PDF A;  3BY4 A;  1AYV A;  3I3T A;  2E02 A;  5K16 A;  3HHI A;  1EWO A;  2OZ2 A;  3LXS A;  3OVX A;  1EWP A;  2VHF A;  4K7C A;  3TMP A;  1U5I A;  2E01 A;  4REZ A;  2P7U A;  2BTW A;  3LFY A;  1CPJ A;  5CHT A;  1TL9 A;  3ZNH A;  3F75 A;  2GFO A;  4CDD B;  4KLB A;  5EF4 A;  3MHS A;  3PRP A;  4X6H A;  2AGA A;  1ME4 A;  1STF E;  1DKI A;  1NB3 A;  3HD3 A;  1NLJ A;  1PE6 A;  2IBI A;  4W4U A;  1KHP A;  2FT2 A;  1NB5 A;  3F5V A;  3V6E A;  4CDC B;  1SNK A;  4XZX A;  5CVO B;  1ME3 A;  4N8W A;  1HUC B;  2DOS A;  3C0R A;  4MSX A;  1ZCM A;  2OUL A;  4RY2 A;  3TRK A;  2PBH A;  2IPP B;  2NQI A;  1MIR A;  1KFU L;  3KX1 A;  4QH6 A;  4YYR A;  2HXZ A;  2HHN A;  3DF0 A;  2G6D A;  1PCI A;  3IEJ A;  4IUM A;  2J7Q A;  4IP3 A;  1VJV A;  1AU2 A;  4ZTB A;  1BGO A;  5F02 A;  4BSQ A;  2G8E A;  1PPN A;  2DCA A;  4YYW A;  2YJ8 A;  1Y4H A;  2DC6 A;  5EZQ A;  1PPD A;  2NQG A;  2B1N A;  2DZY A;  3CBJ A;  1PBH A;  3PSE A;  4FK5 A;  5PAD A;  2CIO A;  3P5U A;  1CQD A;  2FUD A;  2DJG B;  2DC8 A;  2Y6E A;  5EZS A;  2AYN A;  2ATO A;  5KO3 A;  2CB5 A;  3PBH A;  5JZE A;  4DMY A;  1GLO A;  4WA6 A;  4WUR A;  4PAD A;  3CBK A;  1O0E A;  2FRQ A;  8PCH A;  2F7D A;  3PW3 A;  2PAD A;  1CVZ A;  1ATK A;  1M6D A;  2AYO A;  1ICF A;  2YJ9 A;  2YJ2 A;  2HH5 A;  2BTW B;  1AU3 A;  5J94 A;  3D6S A;  4Q8H A;  1YK7 A;  3M99 A;  4M0W A;  4YYS A;  3PNR A;  2G8J A;  2JTC A;  3S3R A;  4RKX A;  3S3Q A;  1AYW A;  4QRV A;  9PAP A;  3MJ5 A;  1THE A;  1F2B A;  1Y08 A;  4MZS A;  1CS8 A;  2FTD A;  5FPW A;  1MHW A;  4HXD B;  3OF8 A;  2AVW A;  3E9S A;  3AI8 A;  3H7D A;  5CHV A;  4QRX A;  3KWZ A;  2R9C A;  5JA7 A;  4D8B A;  3B21 A;  3PHX A;  2F1G A;  2FQ9 A;  3OVZ A;  4MI7 A;  3RVW A;  4BS5 A;  7PCK A;  2R6N A;  4MM3 B;  2BU3 A;  4Q8G A;  2ACT A;  1BQI A;  3BB7 A;  3V6C A;  4AXL A;  4N4Z A;  4A5U A;  3O0U A;  2JQG R;  3KWB X;  4PT5 A;  4I07 A;  1U9X A;  3BBA A;  4XR7 A;  3IV2 A;  1CJL A;  2AUZ A;  4YYV A;  2HWK A;  3PHU A;  4BOS A;  3NHE A;  1VSN A;  3P5V A;  2YJB A;  1AYU A;  5JH3 A;  3WXG A;  3IFU A;  1NL6 A;  2E03 A;  1TU6 A;  4D8I A;  1KHQ A;  3BPF A;  3IUT A;  2HD5 A;  3MOR A;  2FYE A;  1AU4 A;  1MDW A;  3PRM A;  3N3K A;  1CTE A;  1F29 A;  1SP4 B;  2R9O A;  1EWM A;  6PAD A;  3BC3 A;  3MP2 A;  4AXM A;  4OEL A;  3H6S A;  3O65 A;  2P86 A;  1AIM A;  3TNX A;  4BPV A;  3IMA A;  1PIP A;  2DCB A;  2FO5 A;  1GMY A;  3ERV A;  3MTV A;  1UKF A;  4D8E A;  3P5W A;  1QXP A;  1CSB B;  2DZZ A;  3H8C A;  2AUX A;  2XU5 A;  3QT4 A;  3W31 A;  3O1G A;  4BOP A;  3I06 A;  3K9M A;  4QBB A;  1PPP A;  1FH0 A;  1DF0 A;  2AS8 A;  4OVZ A;  2NQD B;  4RF1 A;  1X9Y A;  3WXF A;  4BOU A;  1YVB A;  4PP1 A;  3H8B A;  1JQP A;  1F2A A;  3MHH A;  3GCB A;  1IWD A;  2J7Q C;  3WXE A;  4RNA A;  2E00 A;  2DC9 A;  3BCN A;  3N3G A;  1AU0 A;  1PPO A;  2DJF B;  4PI3 A;  1NPZ A;  5A24 A;  1CV8 A;  2BDL A;  2R9N A;  3BOW A;  4BS6 A;  3KW9 A;  2JRI A;  1TLO A;  1KXR A;  2XU1 A;  1CB5 A;  3BPM A;  1F2C A;  1GEC E;  2B1M A;  2ARY A;  1A6R A;  4YYQ A;  1POP A;  4BQV A;  1NQC A;  2DC7 A;  1PVJ A;  3C9E A;  3HHA A;  4YVA A;  4R3D A;  4W5C A;  1AEC A;  2FE8 A;  1MS6 A;  1ITO A;  3OF9 A;  3BWK A;  5E6J A;  1PAD A;  1U9Q X;  1EF7 A;  1EWL A;  4X6I A;  2WBF X;  4P6E A; 
#chains in the Genus database with same CATH homology
 2C0Y A;  3B79 A;  1DEU A;  3CH2 X;  3IHP A;  2H7J A;  2VHS A;  3RVX A;  4N79 A;  4B55 A;  2FRA A;  1MEM A;  1U9W A;  3RVV A;  1YAL A;  2YJC A;  4CDE B;  3U8E A;  2R9F A;  4CZW A;  2NQA A;  4DMX A;  2PRE A;  1GCB A;  1YT7 A;  2DCC A;  3K24 A;  2XU3 A;  1GX3 A;  2BSZ A;  1ZIV A;  3IOQ A;  1BY8 A;  1MEG A;  4I04 A;  1QMY A;  1QOL A;  4I05 A;  5CVN B;  1QDQ A;  1KFX L;  4FIP A;  1PXV A;  1W4T A;  4OEM A;  4CDF B;  4MZO A;  4HWY A;  1YK8 A;  1XKG A;  4YYU A;  3QSD A;  3KKU A;  2Y5B A;  2PNS A;  3ZUA A;  4FJC A;  5EGW A;  3OIS A;  3H89 A;  1BP4 A;  3N4C A;  5CVM A;  2O6X A;  3KSE A;  4ZUX U;  3HWN A;  3E1Z B;  3KFQ A;  4QRG A;  2GHU A;  2AIM A;  1E2T A;  1Q6K A;  2BDZ A;  3QJ3 A;  3MTN A;  4P6G A;  2JQF R;  1S4V A;  3CH3 X;  2R9M A;  4X6J A;  2OP3 A;  1U9V A;  3K8U A;  4W5B A;  3USV A;  1K3B B;  2XU4 A;  2AU1 A;  4PP2 E;  2DCD A;  3P5X A;  4XUI A;  4YV8 A;  2G7Y A;  4G54 A;  2P0R A;  3PDF A;  1AYV A;  3I3T A;  2E02 A;  5K16 A;  3HHI A;  1EWO A;  2OZ2 A;  1W6F A;  3LXS A;  1EWP A;  3OVX A;  2VHF A;  4K7C A;  1U5I A;  2E01 A;  2P7U A;  3LFY A;  1CPJ A;  5CHT A;  1TL9 A;  3F75 A;  2GFO A;  4CDD B;  4KLB A;  5EF4 A;  3MHS A;  2VFB A;  4X6H A;  1ME4 A;  1STF E;  1NB3 A;  3HD3 A;  1NLJ A;  1PE6 A;  2IBI A;  4W4U A;  1KHP A;  2FT2 A;  1NB5 A;  3F5V A;  3V6E A;  4CDC B;  1SNK A;  5CVO B;  1ME3 A;  4N8W A;  1HUC B;  4MSX A;  1ZCM A;  2OUL A;  4RY2 A;  2PBH A;  2IPP B;  2NQI A;  1MIR A;  1KFU L;  3KX1 A;  4QH6 A;  4YYR A;  2HXZ A;  2HHN A;  3DF0 A;  2G6D A;  1PCI A;  3IEJ A;  1VJV A;  1AU2 A;  1BGO A;  5F02 A;  4BSQ A;  2G8E A;  1PPN A;  2DCA A;  4YYW A;  2YJ8 A;  1Y4H A;  2DC6 A;  1PPD A;  2NQG A;  2B1N A;  2DZY A;  3CBJ A;  1PBH A;  4FK5 A;  5PAD A;  2CIO A;  3P5U A;  1CQD A;  2FUD A;  2DJG B;  4GUZ A;  2DC8 A;  3LTW A;  2Y6E A;  2AYN A;  2ATO A;  2CB5 A;  3PBH A;  4DMY A;  1GLO A;  4WA6 A;  4PAD A;  3CBK A;  1O0E A;  2FRQ A;  8PCH A;  2VFC A;  4C5P A;  2F7D A;  3PW3 A;  2PAD A;  1CVZ A;  1ATK A;  4NV7 A;  1W5R A;  1M6D A;  2AYO A;  1ICF A;  2YJ9 A;  2YJ2 A;  2HH5 A;  1AU3 A;  5J94 A;  3D6S A;  4Q8H A;  1YK7 A;  3M99 A;  4YYS A;  3PNR A;  2G8J A;  3S3R A;  3S3Q A;  1AYW A;  4QRV A;  9PAP A;  1THE A;  1F2B A;  1Y08 A;  4MZS A;  1CS8 A;  2FTD A;  5FPW A;  1MHW A;  3OF8 A;  2AVW A;  3AI8 A;  3H7D A;  5CHV A;  4QRX A;  3KWZ A;  2R9C A;  5JA7 A;  4BS5 A;  2F1G A;  2FQ9 A;  3OVZ A;  3RVW A;  7PCK A;  2R6N A;  4Q8G A;  2ACT A;  1BQI A;  3V6C A;  4AXL A;  4N4Z A;  3O0U A;  2JQG R;  3KWB X;  4I07 A;  1U9X A;  4XR7 A;  3IV2 A;  1CJL A;  2AUZ A;  4YYV A;  3NHE A;  1VSN A;  3P5V A;  2YJB A;  1AYU A;  5JH3 A;  3WXG A;  1NL6 A;  2E03 A;  1TU6 A;  1KHQ A;  3BPF A;  3IUT A;  2HD5 A;  3MOR A;  2FYE A;  1AU4 A;  1MDW A;  3N3K A;  1CTE A;  1F29 A;  1SP4 B;  2R9O A;  1EWM A;  6PAD A;  3BC3 A;  4AXM A;  4OEL A;  3H6S A;  2P86 A;  1AIM A;  3TNX A;  4BGF A;  4BPV A;  3IMA A;  1PIP A;  3D9W A;  2DCB A;  2FO5 A;  1GMY A;  3ERV A;  4NV8 A;  3P5W A;  1QXP A;  1CSB B;  2DZZ A;  3H8C A;  2AUX A;  2XU5 A;  3QT4 A;  3O1G A;  3I06 A;  3K9M A;  4QBB A;  1PPP A;  1FH0 A;  1DF0 A;  2AS8 A;  2NQD B;  3WXF A;  1X9Y A;  1YVB A;  4PP1 A;  3H8B A;  1JQP A;  1F2A A;  3MHH A;  3GCB A;  1IWD A;  3WXE A;  2E00 A;  2DC9 A;  3BCN A;  3N3G A;  1AU0 A;  1PPO A;  2DJF B;  4PI3 A;  1NPZ A;  5A24 A;  1CV8 A;  2BDL A;  2R9N A;  3BOW A;  4BS6 A;  3KW9 A;  1TLO A;  1KXR A;  2XU1 A;  1CB5 A;  3BPM A;  1F2C A;  1GEC E;  2B1M A;  2ARY A;  1A6R A;  4YYQ A;  1POP A;  4BQV A;  1NQC A;  2DC7 A;  3C9E A;  3HHA A;  4YVA A;  4W5C A;  1AEC A;  1MS6 A;  1ITO A;  3OF9 A;  3BWK A;  1PAD A;  1U9Q X;  1EF7 A;  1EWL A;  4X6I A;  2WBF X;  4P6E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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