4QRXA

Crystal structure of pro-papain mutant at ph 4.0
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
304
structure length
292
Chain Sequence
ERLIQLFESWMLKHNKIYKNIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNLSYDVNIPEYVDWRQKGAVTPVKNQGSCGSAWAFSAVSTIESIIKIRTGNLNEYSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYGPNYILIRNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Pro-peptide regulates the substrate specificity and zymogen activation process of papain: A structural and mechanistic insight
rcsb
molecule keywords pro-papain
molecule tags Hydrolase
source organism Carica papaya
total genus 95
structure length 292
sequence length 304
chains with identical sequence C
ec nomenclature ec 3.4.22.2: Papain.
pdb deposition date 2014-07-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
A PF08246 Inhibitor_I29 Cathepsin propeptide inhibitor domain (I29)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 4qrxA00
6PADA 3BOWA 4BS5A 2O6XA 3KX1A 1QOLA 3PW3A 3RVWA 2DCAA 2G8JA 3KWZA 4I05A 2OZ2A 2OULA 4W4UA 1EWMA 4PADA 2YJ2A 3V6EA 3ERVA 1ME4A 1AYUA 1O0EA 2B1MA 5CHVA 2DZZA 1CQDA 1YVBA 1IWDA 1AU4A 3IMAA 4Q8HA 3GCBA 3H8BA 3P5XA 1KXRA 2PREA 2PNSA 1FH0A 3IHPA 2C0YA 1TL9A 4FIPA 3RVVA 3RVXA 2AS8A 2G8EA 3BWKA 2HXZA 4I07A 1PE6A 3H7DA 1Y08A 1MHWA 1MDWA 3CBJA 4ZUXU 3OVXA 1AYVA 4QRGA 4XUIA 3C9EA 7PCKA 1CTEA 1GECE 3HD3A 2E01A 1U9VA 2ARYA 3CBKA 1PADA 4BPVA 2DZYA 1BY8A 5K16A 1K3BB 4W5CA 3QJ3A 1YALA 3DF0A 2PBHA 2E03A 4CZWA 3P5UA 1EWPA 4HWYA 1ICFA 2YJBA 1DEUA 1Q6KA 2G7YA 5FPWA 4W5BA 3KW9A 2R9OA 2DJGB 3H8CA 4XR7A 4YYQA 2FUDA 2YJ9A 4BSQA 4PP1A 4CDCB 3WXGA 2XU4A 4OELA 2DJFB 4YYSA 2P0RA 1YK7A 3S3RA 2FO5A 4KLBA 4N8WA 2P7UA 2GHUA 4P6EA 4X6JA 1BP4A 2CB5A 2NQAA 4YVAA 3K8UA 1PXVA 4PP2E 5JA7A 2FRQA 3LXSA 1NB3A 1CJLA 2ATOA 1CS8A 8PCHA 2E02A 3QT4A 2AUZA 1TLOA 3BPMA 1SP4B 3IOQA 1AYWA 1GCBA 1EWLA 1NL6A 3HHAA 4MSXA 4K7CA 5CHTA 3MORA 3P5VA 4QBBA 2P86A 1CVZA 2VHFA 1NQCA 3F75A 1QXPA 1TU6A 3N3GA 3M99A 2IBIA 4CDEB 2R6NA 4FJCA 4DMXA 1ZIVA 1BQIA 3BCNA 4BS6A 1THEA 3HWNA 3OISA 5PADA 1F2BA 1NLJA 1A6RA 4FK5A 2XU3A 2XU5A 1Y4HA 2DCDA 1XKGA 9PAPA 1AECA 2FTDA 5CVOB 4YYVA 5CVNB 4G54A 1S4VA 1MEMA 2DCCA 1KFXL 4N79A 1PPPA 1F2AA 1HUCB 3KSEA 1CSBB 3N3KA 2NQGA 4P6GA 1U5IA 4YV8A 5EGWA 2HH5A 3U8EA 4QRXA 2DC6A 4MZSA 3IV2A 5EF4A 5CVMA 4I04A 4BQVA 1NPZA 1PIPA 2CIOA 3WXFA 1SNKA 5F02A 2HHNA 5JH3A 4CDFB 1U9XA 3KWBX 1YT7A 3H89A 3KFQA 4QH6A 1X9YA 2BDLA 3O0UA 3NHEA 4YYRA 1DF0A 4QRVA 2Y5BA 1ME3A 1AU3A 3I06A 3TNXA 1PPNA 4AXMA 3OF9A 2NQIA 1QMYA 1F2CA 1VJVA 3PDFA 2H7JA 3IUTA 4YYUA 2FT2A 2DC7A 1AU0A 2Y6EA 2OP3A 4Q8GA 1YK8A 2XU1A 1QDQA 1PCIA 2FYEA 1GLOA 4CDDB 3V6CA 5A24A 1AIMA 4RY2A 3USVA 2DC9A 3BPFA 2DCBA 4AXLA 4PI3A 2F1GA 2B1NA 3CH3X 3D6SA 1MS6A 1AU2A 1JQPA 4X6IA 3S3QA 2AYOA 1POPA 4N4ZA 3PNRA 3MTNA 3OVZA 2JQFR 1MIRA 1STFE 1ZCMA 1ITOA 3IEJA 1BGOA 3OF8A 1GMYA 3LFYA 3P5WA 2WBFX 3AI8A 1U9QX 4OEMA 2F7DA 1PPOA 2FQ9A 1CV8A 3QSDA 2DC8A 3MHSA 4X6HA 1KHQA 2NQDB 3K24A 1EF7A 2AU1A 4DMYA 2GFOA 3PBHA 2R9CA 2AUXA 1PBHA 3CH2X 3KKUA 1CB5A 2AVWA 3E1ZB 2R9MA 1F29A 2YJCA 3H6SA 4WA6A 1U9WA 1M6DA 2R9FA 3MHHA 1ATKA 3ZUAA 1EWOA 1VSNA 1KFUL 2FRAA 3F5VA 3N4CA 1PPDA 2JQGR 1KHPA 1MEGA 2G6DA 5J94A 2YJ8A 2VHSA 2IPPB 3O1GA 1NB5A 3BC3A 4MZOA 3HHIA 3I3TA 2AYNA 2E00A 3K9MA 3B79A 1CPJA 2ACTA 2BDZA 2AIMA 2PADA 4YYWA 2HD5A 2R9NA 3WXEA
chains in the Genus database with same CATH superfamily
6PADA 4RKXA 3BOWA 4BS5A 2O6XA 3KX1A 2BTWB 1QOLA 4PT5A 3PW3A 3RVWA 2DCAA 4MI7A 2G8JA 3KWZA 4I05A 2OZ2A 1UKFA 2OULA 4W4UA 1EWMA 4PADA 2YJ2A 3V6EA 4BOSA 3ERVA 1ME4A 1AYUA 3BBAA 1O0EA 2B1MA 3PT2A 5CHVA 2DZZA 1CQDA 1YVBA 1IWDA 1YZBA 1AU4A 3IMAA 4Q8HA 3GCBA 3H8BA 3P5XA 1KXRA 4D8EA 2PREA 2PNSA 1FH0A 3IHPA 2C0YA 1TL9A 4FIPA 3RVVA 3RVXA 2AS8A 2G8EA 3BWKA 2HXZA 4I07A 3TRKA 1PE6A 3H7DA 1Y08A 3C0RA 1MHWA 5EZSA 1MDWA 3CBJA 4ZUXU 3OVXA 3MP2A 1AYVA 4QRGA 4XUIA 5E6JA 3C9EA 3BY4A 7PCKA 1CTEA 3B21A 1GECE 3O65A 3HD3A 2E01A 1U9VA 2ARYA 3CBKA 3E9SA 1PADA 4BPVA 2DZYA 1BY8A 3PHUA 5K16A 1K3BB 4W5CA 3QJ3A 4XZXA 1YALA 3DF0A 2PBHA 2E03A 4CZWA 3P5UA 1EWPA 4HWYA 1ICFA 2YJBA 1DEUA 1Q6KA 2G7YA 2UZJA 5FPWA 4W5BA 3KW9A 2R9OA 3PHWA 2DJGB 3H8CA 4XR7A 4YYQA 2FUDA 2YJ9A 4BSQA 4BOPA 4PP1A 4CDCB 2J7QA 3WXGA 2XU4A 4OELA 2DJFB 4YYSA 2P0RA 1YK7A 3S3RA 4BOUA 2FO5A 4KLBA 4N8WA 2P7UA 2GHUA 4P6EA 4X6JA 1BP4A 2CB5A 2NQAA 4YVAA 3K8UA 1PXVA 4PP2E 2Z84A 5JA7A 2FRQA 3LXSA 1NB3A 1CJLA 2ATOA 1CS8A 8PCHA 2E02A 3QT4A 2AUZA 1TLOA 3BPMA 1SP4B 3IOQA 1AYWA 4IUMA 1GCBA 1EWLA 4REZA 1NL6A 3HHAA 4MSXA 4K7CA 5CHTA 3MORA 3P5VA 4QBBA 2P86A 1CVZA 2VHFA 1NQCA 3F75A 3MJ5A 1QXPA 1TU6A 3N3GA 3M99A 2IBIA 4CDEB 2R6NA 4FJCA 4DMXA 1ZIVA 1BQIA 3BCNA 4BS6A 1THEA 3HWNA 5KO3A 3OISA 5PADA 3IFUA 1F2BA 1NLJA 1PVJA 1A6RA 4FK5A 2XU3A 2XU5A 1Y4HA 4OVZA 2DCDA 1XKGA 9PAPA 1AECA 2FTDA 5CVOB 4YYVA 5CVNB 4G54A 1S4VA 1MEMA 2DCCA 3BB7A 1KFXL 4N79A 1PPPA 1F2AA 4GUAA 1HUCB 3KSEA 3PRMA 3TMPA 1CSBB 3N3KA 2NQGA 4P6GA 1U5IA 4YV8A 5EGWA 2HH5A 2J7QC 4P16A 4OW0A 3U8EA 4QRXA 2DC6A 4MZSA 3IV2A 5EF4A 5CVMA 4I04A 4BQVA 1NPZA 1PIPA 2CIOA 3WXFA 1SNKA 4BOQA 5F02A 1DKIA 2HHNA 5JH3A 4RF0A 4CDFB 1U9XA 3KWBX 3W31A 1YT7A 3H89A 3KFQA 4QH6A 1X9YA 2BDLA 3O0UA 3NHEA 3RNVA 4YYRA 1DF0A 4QRVA 2Y5BA 1ME3A 1AU3A 3I06A 3TNXA 3PSEA 1PPNA 4AXMA 3OF9A 3W30A 2NQIA 1QMYA 1F2CA 1VJVA 3PDFA 2H7JA 3IUTA 4YYUA 4OVZB 2FT2A 2DC7A 2AGAA 1AU0A 4RNAA 2Y6EA 2OP3A 4Q8GA 1YK8A 2XU1A 1QDQA 1PCIA 5EZQA 2FYEA 1GLOA 4CDDB 3V6CA 5A24A 1AIMA 4RY2A 3USVA 2DC9A 3BPFA 2DCBA 3PRPA 4AXLA 4PI3A 2F1GA 2B1NA 4BOZA 3CH3X 3D6SA 1MS6A 1AU2A 1JQPA 4X6IA 3S3QA 2AYOA 4M0WA 1POPA 4N4ZA 3PNRA 3MTNA 4IP3A 3OVZA 4RF1A 2JQFR 2JTCA 1MIRA 1STFE 1ZCMA 1ITOA 3IEJA 1BGOA 2BU3A 3OF8A 1GMYA 3LFYA 3P5WA 2WBFX 3AI8A 1U9QX 4OEMA 2F7DA 2HWKA 1PPOA 2FE8A 2FQ9A 1CV8A 3QSDA 2DC8A 3MHSA 2JRIA 2BTWA 4X6HA 1KHQA 2NQDB 3K24A 1EF7A 2AU1A 4DMYA 2GFOA 3PBHA 3ZNHA 2R9CA 2AUXA 1PBHA 3CH2X 3KKUA 1CB5A 3MTVA 3OQCA 2AVWA 3E1ZB 2R9MA 1F29A 2YJCA 3H6SA 4WA6A 1U9WA 1M6DA 2R9FA 3MHHA 1ATKA 4A5UA 3ZUAA 4MM3B 1EWOA 1VSNA 4D8BA 1KFUL 2FRAA 3F5VA 4ZTBA 3N4CA 1PPDA 2JQGR 1KHPA 1MEGA 2G6DA 5J94A 4D8IA 2YJ8A 2VHSA 2IPPB 3O1GA 4HXDB 1NB5A 3BC3A 4MZOA 3HHIA 4WURA 3I3TA 5JZEA 2AYNA 2E00A 3K9MA 3B79A 1CPJA 2ACTA 2BDZA 2AIMA 4R3DA 2PADA 4YYWA 2DOSA 2HD5A 2R9NA 3WXEA 3PHXA
chains in the Genus database with same CATH topology
6PADA 3BOWA 4BS5A 2O6XA 3KX1A 1QOLA 3PW3A 3RVWA 2DCAA 2G8JA 3KWZA 4I05A 2OZ2A 2OULA 4W4UA 1EWMA 4PADA 2YJ2A 3V6EA 3ERVA 1ME4A 1AYUA 1O0EA 1GX3A 2B1MA 5CHVA 2DZZA 1CQDA 1YVBA 1IWDA 1W6FA 1AU4A 3IMAA 4Q8HA 3GCBA 3H8BA 3P5XA 1KXRA 2PREA 2PNSA 1FH0A 3IHPA 2C0YA 1TL9A 4FIPA 3RVVA 3RVXA 2AS8A 2G8EA 3BWKA 2HXZA 4I07A 4BGFA 1PE6A 3H7DA 1Y08A 1MHWA 1MDWA 3CBJA 4ZUXU 3OVXA 1AYVA 4QRGA 4XUIA 3C9EA 7PCKA 1CTEA 1GECE 3HD3A 2E01A 1U9VA 2ARYA 3CBKA 4GUZA 1PADA 4BPVA 2DZYA 1BY8A 5K16A 1K3BB 4W5CA 3QJ3A 1YALA 3DF0A 2PBHA 2E03A 4CZWA 3P5UA 1EWPA 4HWYA 1ICFA 2YJBA 1E2TA 1DEUA 1Q6KA 2G7YA 5FPWA 4W5BA 3KW9A 2R9OA 2DJGB 3H8CA 4XR7A 4YYQA 2FUDA 2YJ9A 4BSQA 4PP1A 4CDCB 3WXGA 2XU4A 2VFBA 2DJFB 4OELA 4YYSA 2P0RA 1YK7A 3S3RA 2FO5A 4KLBA 4N8WA 2P7UA 2GHUA 2BSZA 4P6EA 4X6JA 1BP4A 2CB5A 2NQAA 4YVAA 4NV7A 3K8UA 1PXVA 4PP2E 5JA7A 2FRQA 3LXSA 1NB3A 1CJLA 2ATOA 1CS8A 8PCHA 2E02A 3QT4A 2AUZA 1TLOA 3BPMA 1SP4B 3IOQA 1AYWA 1GCBA 1EWLA 1NL6A 3HHAA 4MSXA 4K7CA 5CHTA 3MORA 3P5VA 4QBBA 2P86A 1CVZA 2VHFA 1NQCA 3F75A 1QXPA 1TU6A 3N3GA 3M99A 2IBIA 4CDEB 2R6NA 4FJCA 4DMXA 1ZIVA 1BQIA 3BCNA 4BS6A 1THEA 3HWNA 3OISA 5PADA 1F2BA 1NLJA 1A6RA 4FK5A 2XU3A 2XU5A 1Y4HA 2DCDA 1XKGA 9PAPA 1AECA 2FTDA 5CVOB 4YYVA 4C5PA 5CVNB 4G54A 1S4VA 1MEMA 2DCCA 1KFXL 4N79A 1PPPA 1F2AA 1HUCB 3KSEA 1CSBB 3N3KA 2NQGA 4P6GA 1U5IA 4YV8A 5EGWA 2HH5A 3U8EA 4B55A 4QRXA 2DC6A 4MZSA 3IV2A 5EF4A 5CVMA 4I04A 4BQVA 4NV8A 1NPZA 1PIPA 2CIOA 3WXFA 1SNKA 5F02A 2HHNA 5JH3A 4CDFB 1U9XA 3KWBX 1YT7A 3H89A 3KFQA 4QH6A 1X9YA 2BDLA 3O0UA 3NHEA 4YYRA 1DF0A 4QRVA 2Y5BA 1ME3A 1AU3A 3I06A 3TNXA 1PPNA 4AXMA 3OF9A 2NQIA 1QMYA 1F2CA 1VJVA 3PDFA 2H7JA 3IUTA 4YYUA 2FT2A 2DC7A 1AU0A 2Y6EA 2OP3A 4Q8GA 1YK8A 2VFCA 2XU1A 1QDQA 1PCIA 2FYEA 1GLOA 4CDDB 3V6CA 5A24A 1AIMA 4RY2A 3USVA 2DC9A 3BPFA 2DCBA 4AXLA 4PI3A 2F1GA 2B1NA 3CH3X 3D6SA 1MS6A 1AU2A 1JQPA 4X6IA 3S3QA 2AYOA 1POPA 4N4ZA 3PNRA 3MTNA 3OVZA 2JQFR 1MIRA 1STFE 1ZCMA 3D9WA 1ITOA 3IEJA 1BGOA 3OF8A 1GMYA 3LFYA 3P5WA 2WBFX 3AI8A 1U9QX 4OEMA 2F7DA 1PPOA 2FQ9A 1CV8A 3QSDA 2DC8A 3MHSA 4X6HA 1KHQA 3LTWA 2NQDB 3K24A 1EF7A 2AU1A 4DMYA 2GFOA 1W5RA 3PBHA 2R9CA 2AUXA 1PBHA 3CH2X 3KKUA 1CB5A 2AVWA 3E1ZB 2R9MA 1F29A 2YJCA 3H6SA 4WA6A 1U9WA 1M6DA 2R9FA 3MHHA 1ATKA 3ZUAA 1EWOA 1VSNA 1W4TA 1KFUL 2FRAA 3F5VA 3N4CA 1PPDA 2JQGR 1KHPA 1MEGA 2G6DA 5J94A 2YJ8A 2VHSA 2IPPB 3O1GA 1NB5A 3BC3A 4MZOA 3HHIA 3I3TA 2AYNA 2E00A 3K9MA 3B79A 1CPJA 2ACTA 2BDZA 2AIMA 2PADA 4YYWA 2HD5A 2R9NA 3WXEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 6PAD A;  3BOW A;  4BS5 A;  2O6X A;  3KX1 A;  1QOL A;  3PW3 A;  3RVW A;  2DCA A;  2G8J A;  3KWZ A;  4I05 A;  2OZ2 A;  2OUL A;  4W4U A;  1EWM A;  4PAD A;  2YJ2 A;  3V6E A;  3ERV A;  1ME4 A;  1AYU A;  1O0E A;  2B1M A;  5CHV A;  2DZZ A;  1CQD A;  1YVB A;  1IWD A;  1AU4 A;  3IMA A;  4Q8H A;  3GCB A;  3H8B A;  3P5X A;  1KXR A;  2PRE A;  2PNS A;  1FH0 A;  3IHP A;  2C0Y A;  1TL9 A;  4FIP A;  3RVV A;  3RVX A;  2AS8 A;  2G8E A;  3BWK A;  2HXZ A;  4I07 A;  1PE6 A;  3H7D A;  1Y08 A;  1MHW A;  1MDW A;  3CBJ A;  4ZUX U;  3OVX A;  1AYV A;  4QRG A;  4XUI A;  3C9E A;  7PCK A;  1CTE A;  1GEC E;  3HD3 A;  2E01 A;  1U9V A;  2ARY A;  3CBK A;  1PAD A;  4BPV A;  2DZY A;  1BY8 A;  5K16 A;  1K3B B;  4W5C A;  3QJ3 A;  1YAL A;  3DF0 A;  2PBH A;  2E03 A;  4CZW A;  3P5U A;  1EWP A;  4HWY A;  1ICF A;  2YJB A;  1DEU A;  1Q6K A;  2G7Y A;  5FPW A;  4W5B A;  3KW9 A;  2R9O A;  2DJG B;  3H8C A;  4XR7 A;  4YYQ A;  2FUD A;  2YJ9 A;  4BSQ A;  4PP1 A;  4CDC B;  3WXG A;  2XU4 A;  4OEL A;  2DJF B;  4YYS A;  2P0R A;  1YK7 A;  3S3R A;  2FO5 A;  4KLB A;  4N8W A;  2P7U A;  2GHU A;  4P6E A;  4X6J A;  1BP4 A;  2CB5 A;  2NQA A;  4YVA A;  3K8U A;  1PXV A;  4PP2 E;  5JA7 A;  2FRQ A;  3LXS A;  1NB3 A;  1CJL A;  2ATO A;  1CS8 A;  8PCH A;  2E02 A;  3QT4 A;  2AUZ A;  1TLO A;  3BPM A;  1SP4 B;  3IOQ A;  1AYW A;  1GCB A;  1EWL A;  1NL6 A;  3HHA A;  4MSX A;  4K7C A;  5CHT A;  3MOR A;  3P5V A;  4QBB A;  2P86 A;  1CVZ A;  2VHF A;  1NQC A;  3F75 A;  1QXP A;  1TU6 A;  3N3G A;  3M99 A;  2IBI A;  4CDE B;  2R6N A;  4FJC A;  4DMX A;  1ZIV A;  1BQI A;  3BCN A;  4BS6 A;  1THE A;  3HWN A;  3OIS A;  5PAD A;  1F2B A;  1NLJ A;  1A6R A;  4FK5 A;  2XU3 A;  2XU5 A;  1Y4H A;  2DCD A;  1XKG A;  9PAP A;  1AEC A;  2FTD A;  5CVO B;  4YYV A;  5CVN B;  4G54 A;  1S4V A;  1MEM A;  2DCC A;  1KFX L;  4N79 A;  1PPP A;  1F2A A;  1HUC B;  3KSE A;  1CSB B;  3N3K A;  2NQG A;  4P6G A;  1U5I A;  4YV8 A;  5EGW A;  2HH5 A;  3U8E A;  4QRX A;  2DC6 A;  4MZS A;  3IV2 A;  5EF4 A;  5CVM A;  4I04 A;  4BQV A;  1NPZ A;  1PIP A;  2CIO A;  3WXF A;  1SNK A;  5F02 A;  2HHN A;  5JH3 A;  4CDF B;  1U9X A;  3KWB X;  1YT7 A;  3H89 A;  3KFQ A;  4QH6 A;  1X9Y A;  2BDL A;  3O0U A;  3NHE A;  4YYR A;  1DF0 A;  4QRV A;  2Y5B A;  1ME3 A;  1AU3 A;  3I06 A;  3TNX A;  1PPN A;  4AXM A;  3OF9 A;  2NQI A;  1QMY A;  1F2C A;  1VJV A;  3PDF A;  2H7J A;  3IUT A;  4YYU A;  2FT2 A;  2DC7 A;  1AU0 A;  2Y6E A;  2OP3 A;  4Q8G A;  1YK8 A;  2XU1 A;  1QDQ A;  1PCI A;  2FYE A;  1GLO A;  4CDD B;  3V6C A;  5A24 A;  1AIM A;  4RY2 A;  3USV A;  2DC9 A;  3BPF A;  2DCB A;  4AXL A;  4PI3 A;  2F1G A;  2B1N A;  3CH3 X;  3D6S A;  1MS6 A;  1AU2 A;  1JQP A;  4X6I A;  3S3Q A;  2AYO A;  1POP A;  4N4Z A;  3PNR A;  3MTN A;  3OVZ A;  2JQF R;  1MIR A;  1STF E;  1ZCM A;  1ITO A;  3IEJ A;  1BGO A;  3OF8 A;  1GMY A;  3LFY A;  3P5W A;  2WBF X;  3AI8 A;  1U9Q X;  4OEM A;  2F7D A;  1PPO A;  2FQ9 A;  1CV8 A;  3QSD A;  2DC8 A;  3MHS A;  4X6H A;  1KHQ A;  2NQD B;  3K24 A;  1EF7 A;  2AU1 A;  4DMY A;  2GFO A;  3PBH A;  2R9C A;  2AUX A;  1PBH A;  3CH2 X;  3KKU A;  1CB5 A;  2AVW A;  3E1Z B;  2R9M A;  1F29 A;  2YJC A;  3H6S A;  4WA6 A;  1U9W A;  1M6D A;  2R9F A;  3MHH A;  1ATK A;  3ZUA A;  1EWO A;  1VSN A;  1KFU L;  2FRA A;  3F5V A;  3N4C A;  1PPD A;  2JQG R;  1KHP A;  1MEG A;  2G6D A;  5J94 A;  2YJ8 A;  2VHS A;  2IPP B;  3O1G A;  1NB5 A;  3BC3 A;  4MZO A;  3HHI A;  3I3T A;  2AYN A;  2E00 A;  3K9M A;  3B79 A;  1CPJ A;  2ACT A;  2BDZ A;  2AIM A;  2PAD A;  4YYW A;  2HD5 A;  2R9N A;  3WXE A; 
#chains in the Genus database with same CATH topology
 6PAD A;  4RKX A;  3BOW A;  4BS5 A;  2O6X A;  3KX1 A;  2BTW B;  1QOL A;  4PT5 A;  3PW3 A;  3RVW A;  2DCA A;  4MI7 A;  2G8J A;  3KWZ A;  4I05 A;  2OZ2 A;  1UKF A;  2OUL A;  4W4U A;  1EWM A;  4PAD A;  2YJ2 A;  3V6E A;  4BOS A;  3ERV A;  1ME4 A;  1AYU A;  3BBA A;  1O0E A;  2B1M A;  3PT2 A;  5CHV A;  2DZZ A;  1CQD A;  1YVB A;  1IWD A;  1YZB A;  1AU4 A;  3IMA A;  4Q8H A;  3GCB A;  3H8B A;  3P5X A;  1KXR A;  4D8E A;  2PRE A;  2PNS A;  1FH0 A;  3IHP A;  2C0Y A;  1TL9 A;  4FIP A;  3RVV A;  3RVX A;  2AS8 A;  2G8E A;  3BWK A;  2HXZ A;  4I07 A;  3TRK A;  1PE6 A;  3H7D A;  1Y08 A;  3C0R A;  1MHW A;  5EZS A;  1MDW A;  3CBJ A;  4ZUX U;  3OVX A;  3MP2 A;  1AYV A;  4QRG A;  4XUI A;  5E6J A;  3C9E A;  3BY4 A;  7PCK A;  1CTE A;  3B21 A;  1GEC E;  3O65 A;  3HD3 A;  2E01 A;  1U9V A;  2ARY A;  3CBK A;  3E9S A;  1PAD A;  4BPV A;  2DZY A;  1BY8 A;  3PHU A;  5K16 A;  1K3B B;  4W5C A;  3QJ3 A;  4XZX A;  1YAL A;  3DF0 A;  2PBH A;  2E03 A;  4CZW A;  3P5U A;  1EWP A;  4HWY A;  1ICF A;  2YJB A;  1DEU A;  1Q6K A;  2G7Y A;  2UZJ A;  5FPW A;  4W5B A;  3KW9 A;  2R9O A;  3PHW A;  2DJG B;  3H8C A;  4XR7 A;  4YYQ A;  2FUD A;  2YJ9 A;  4BSQ A;  4BOP A;  4PP1 A;  4CDC B;  2J7Q A;  3WXG A;  2XU4 A;  4OEL A;  2DJF B;  4YYS A;  2P0R A;  1YK7 A;  3S3R A;  4BOU A;  2FO5 A;  4KLB A;  4N8W A;  2P7U A;  2GHU A;  4P6E A;  4X6J A;  1BP4 A;  2CB5 A;  2NQA A;  4YVA A;  3K8U A;  1PXV A;  4PP2 E;  2Z84 A;  5JA7 A;  2FRQ A;  3LXS A;  1NB3 A;  1CJL A;  2ATO A;  1CS8 A;  8PCH A;  2E02 A;  3QT4 A;  2AUZ A;  1TLO A;  3BPM A;  1SP4 B;  3IOQ A;  1AYW A;  4IUM A;  1GCB A;  1EWL A;  4REZ A;  1NL6 A;  3HHA A;  4MSX A;  4K7C A;  5CHT A;  3MOR A;  3P5V A;  4QBB A;  2P86 A;  1CVZ A;  2VHF A;  1NQC A;  3F75 A;  3MJ5 A;  1QXP A;  1TU6 A;  3N3G A;  3M99 A;  2IBI A;  4CDE B;  2R6N A;  4FJC A;  4DMX A;  1ZIV A;  1BQI A;  3BCN A;  4BS6 A;  1THE A;  3HWN A;  5KO3 A;  3OIS A;  5PAD A;  3IFU A;  1F2B A;  1NLJ A;  1PVJ A;  1A6R A;  4FK5 A;  2XU3 A;  2XU5 A;  1Y4H A;  4OVZ A;  2DCD A;  1XKG A;  9PAP A;  1AEC A;  2FTD A;  5CVO B;  4YYV A;  5CVN B;  4G54 A;  1S4V A;  1MEM A;  2DCC A;  3BB7 A;  1KFX L;  4N79 A;  1PPP A;  1F2A A;  4GUA A;  1HUC B;  3KSE A;  3PRM A;  3TMP A;  1CSB B;  3N3K A;  2NQG A;  4P6G A;  1U5I A;  4YV8 A;  5EGW A;  2HH5 A;  2J7Q C;  4P16 A;  4OW0 A;  3U8E A;  4QRX A;  2DC6 A;  4MZS A;  3IV2 A;  5EF4 A;  5CVM A;  4I04 A;  4BQV A;  1NPZ A;  1PIP A;  2CIO A;  3WXF A;  1SNK A;  4BOQ A;  5F02 A;  1DKI A;  2HHN A;  5JH3 A;  4RF0 A;  4CDF B;  1U9X A;  3KWB X;  3W31 A;  1YT7 A;  3H89 A;  3KFQ A;  4QH6 A;  1X9Y A;  2BDL A;  3O0U A;  3NHE A;  3RNV A;  4YYR A;  1DF0 A;  4QRV A;  2Y5B A;  1ME3 A;  1AU3 A;  3I06 A;  3TNX A;  3PSE A;  1PPN A;  4AXM A;  3OF9 A;  3W30 A;  2NQI A;  1QMY A;  1F2C A;  1VJV A;  3PDF A;  2H7J A;  3IUT A;  4YYU A;  4OVZ B;  2FT2 A;  2DC7 A;  2AGA A;  1AU0 A;  4RNA A;  2Y6E A;  2OP3 A;  4Q8G A;  1YK8 A;  2XU1 A;  1QDQ A;  1PCI A;  5EZQ A;  2FYE A;  1GLO A;  4CDD B;  3V6C A;  5A24 A;  1AIM A;  4RY2 A;  3USV A;  2DC9 A;  3BPF A;  2DCB A;  3PRP A;  4AXL A;  4PI3 A;  2F1G A;  2B1N A;  4BOZ A;  3CH3 X;  3D6S A;  1MS6 A;  1AU2 A;  1JQP A;  4X6I A;  3S3Q A;  2AYO A;  4M0W A;  1POP A;  4N4Z A;  3PNR A;  3MTN A;  4IP3 A;  3OVZ A;  4RF1 A;  2JQF R;  2JTC A;  1MIR A;  1STF E;  1ZCM A;  1ITO A;  3IEJ A;  1BGO A;  2BU3 A;  3OF8 A;  1GMY A;  3LFY A;  3P5W A;  2WBF X;  3AI8 A;  1U9Q X;  4OEM A;  2F7D A;  2HWK A;  1PPO A;  2FE8 A;  2FQ9 A;  1CV8 A;  3QSD A;  2DC8 A;  3MHS A;  2JRI A;  2BTW A;  4X6H A;  1KHQ A;  2NQD B;  3K24 A;  1EF7 A;  2AU1 A;  4DMY A;  2GFO A;  3PBH A;  3ZNH A;  2R9C A;  2AUX A;  1PBH A;  3CH2 X;  3KKU A;  1CB5 A;  3MTV A;  3OQC A;  2AVW A;  3E1Z B;  2R9M A;  1F29 A;  2YJC A;  3H6S A;  4WA6 A;  1U9W A;  1M6D A;  2R9F A;  3MHH A;  1ATK A;  4A5U A;  3ZUA A;  4MM3 B;  1EWO A;  1VSN A;  4D8B A;  1KFU L;  2FRA A;  3F5V A;  4ZTB A;  3N4C A;  1PPD A;  2JQG R;  1KHP A;  1MEG A;  2G6D A;  5J94 A;  4D8I A;  2YJ8 A;  2VHS A;  2IPP B;  3O1G A;  4HXD B;  1NB5 A;  3BC3 A;  4MZO A;  3HHI A;  4WUR A;  3I3T A;  5JZE A;  2AYN A;  2E00 A;  3K9M A;  3B79 A;  1CPJ A;  2ACT A;  2BDZ A;  2AIM A;  4R3D A;  2PAD A;  4YYW A;  2DOS A;  2HD5 A;  2R9N A;  3WXE A;  3PHX A; 
#chains in the Genus database with same CATH homology
 6PAD A;  3BOW A;  4BS5 A;  2O6X A;  3KX1 A;  1QOL A;  3PW3 A;  3RVW A;  2DCA A;  2G8J A;  3KWZ A;  4I05 A;  2OZ2 A;  2OUL A;  4W4U A;  1EWM A;  4PAD A;  2YJ2 A;  3V6E A;  3ERV A;  1ME4 A;  1AYU A;  1O0E A;  1GX3 A;  2B1M A;  5CHV A;  2DZZ A;  1CQD A;  1YVB A;  1IWD A;  1W6F A;  1AU4 A;  3IMA A;  4Q8H A;  3GCB A;  3H8B A;  3P5X A;  1KXR A;  2PRE A;  2PNS A;  1FH0 A;  3IHP A;  2C0Y A;  1TL9 A;  4FIP A;  3RVV A;  3RVX A;  2AS8 A;  2G8E A;  3BWK A;  2HXZ A;  4I07 A;  4BGF A;  1PE6 A;  3H7D A;  1Y08 A;  1MHW A;  1MDW A;  3CBJ A;  4ZUX U;  3OVX A;  1AYV A;  4QRG A;  4XUI A;  3C9E A;  7PCK A;  1CTE A;  1GEC E;  3HD3 A;  2E01 A;  1U9V A;  2ARY A;  3CBK A;  4GUZ A;  1PAD A;  4BPV A;  2DZY A;  1BY8 A;  5K16 A;  1K3B B;  4W5C A;  3QJ3 A;  1YAL A;  3DF0 A;  2PBH A;  2E03 A;  4CZW A;  3P5U A;  1EWP A;  4HWY A;  1ICF A;  2YJB A;  1E2T A;  1DEU A;  1Q6K A;  2G7Y A;  5FPW A;  4W5B A;  3KW9 A;  2R9O A;  2DJG B;  3H8C A;  4XR7 A;  4YYQ A;  2FUD A;  2YJ9 A;  4BSQ A;  4PP1 A;  4CDC B;  3WXG A;  2XU4 A;  2VFB A;  2DJF B;  4OEL A;  4YYS A;  2P0R A;  1YK7 A;  3S3R A;  2FO5 A;  4KLB A;  4N8W A;  2P7U A;  2GHU A;  2BSZ A;  4P6E A;  4X6J A;  1BP4 A;  2CB5 A;  2NQA A;  4YVA A;  4NV7 A;  3K8U A;  1PXV A;  4PP2 E;  5JA7 A;  2FRQ A;  3LXS A;  1NB3 A;  1CJL A;  2ATO A;  1CS8 A;  8PCH A;  2E02 A;  3QT4 A;  2AUZ A;  1TLO A;  3BPM A;  1SP4 B;  3IOQ A;  1AYW A;  1GCB A;  1EWL A;  1NL6 A;  3HHA A;  4MSX A;  4K7C A;  5CHT A;  3MOR A;  3P5V A;  4QBB A;  2P86 A;  1CVZ A;  2VHF A;  1NQC A;  3F75 A;  1QXP A;  1TU6 A;  3N3G A;  3M99 A;  2IBI A;  4CDE B;  2R6N A;  4FJC A;  4DMX A;  1ZIV A;  1BQI A;  3BCN A;  4BS6 A;  1THE A;  3HWN A;  3OIS A;  5PAD A;  1F2B A;  1NLJ A;  1A6R A;  4FK5 A;  2XU3 A;  2XU5 A;  1Y4H A;  2DCD A;  1XKG A;  9PAP A;  1AEC A;  2FTD A;  5CVO B;  4YYV A;  4C5P A;  5CVN B;  4G54 A;  1S4V A;  1MEM A;  2DCC A;  1KFX L;  4N79 A;  1PPP A;  1F2A A;  1HUC B;  3KSE A;  1CSB B;  3N3K A;  2NQG A;  4P6G A;  1U5I A;  4YV8 A;  5EGW A;  2HH5 A;  3U8E A;  4B55 A;  4QRX A;  2DC6 A;  4MZS A;  3IV2 A;  5EF4 A;  5CVM A;  4I04 A;  4BQV A;  4NV8 A;  1NPZ A;  1PIP A;  2CIO A;  3WXF A;  1SNK A;  5F02 A;  2HHN A;  5JH3 A;  4CDF B;  1U9X A;  3KWB X;  1YT7 A;  3H89 A;  3KFQ A;  4QH6 A;  1X9Y A;  2BDL A;  3O0U A;  3NHE A;  4YYR A;  1DF0 A;  4QRV A;  2Y5B A;  1ME3 A;  1AU3 A;  3I06 A;  3TNX A;  1PPN A;  4AXM A;  3OF9 A;  2NQI A;  1QMY A;  1F2C A;  1VJV A;  3PDF A;  2H7J A;  3IUT A;  4YYU A;  2FT2 A;  2DC7 A;  1AU0 A;  2Y6E A;  2OP3 A;  4Q8G A;  1YK8 A;  2VFC A;  2XU1 A;  1QDQ A;  1PCI A;  2FYE A;  1GLO A;  4CDD B;  3V6C A;  5A24 A;  1AIM A;  4RY2 A;  3USV A;  2DC9 A;  3BPF A;  2DCB A;  4AXL A;  4PI3 A;  2F1G A;  2B1N A;  3CH3 X;  3D6S A;  1MS6 A;  1AU2 A;  1JQP A;  4X6I A;  3S3Q A;  2AYO A;  1POP A;  4N4Z A;  3PNR A;  3MTN A;  3OVZ A;  2JQF R;  1MIR A;  1STF E;  1ZCM A;  3D9W A;  1ITO A;  3IEJ A;  1BGO A;  3OF8 A;  1GMY A;  3LFY A;  3P5W A;  2WBF X;  3AI8 A;  1U9Q X;  4OEM A;  2F7D A;  1PPO A;  2FQ9 A;  1CV8 A;  3QSD A;  2DC8 A;  3MHS A;  4X6H A;  1KHQ A;  3LTW A;  2NQD B;  3K24 A;  1EF7 A;  2AU1 A;  4DMY A;  2GFO A;  1W5R A;  3PBH A;  2R9C A;  2AUX A;  1PBH A;  3CH2 X;  3KKU A;  1CB5 A;  2AVW A;  3E1Z B;  2R9M A;  1F29 A;  2YJC A;  3H6S A;  4WA6 A;  1U9W A;  1M6D A;  2R9F A;  3MHH A;  1ATK A;  3ZUA A;  1EWO A;  1VSN A;  1W4T A;  1KFU L;  2FRA A;  3F5V A;  3N4C A;  1PPD A;  2JQG R;  1KHP A;  1MEG A;  2G6D A;  5J94 A;  2YJ8 A;  2VHS A;  2IPP B;  3O1G A;  1NB5 A;  3BC3 A;  4MZO A;  3HHI A;  3I3T A;  2AYN A;  2E00 A;  3K9M A;  3B79 A;  1CPJ A;  2ACT A;  2BDZ A;  2AIM A;  2PAD A;  4YYW A;  2HD5 A;  2R9N A;  3WXE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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