2NQIA

Calpain 1 proteolytic core inactivated by wr13(r,r), an epoxysuccinyl-type inhibitor.
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
322
structure length
322
Chain Sequence
NAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICNLT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Development of Calpain-specific Inactivators by Screening of Positional Scanning Epoxide Libraries
pubmed doi rcsb
molecule keywords Calpain-1 catalytic subunit
source organism Rattus norvegicus
molecule tags Hydrolase
total genus 96
structure length 322
sequence length 322
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2006-10-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2nqiA02
1AYVA 1ME3A 1F2AA 2AIMA 4W5BA 2XU5A 1KFXL 1AYWA 2PADA 1ZCMA 2DCBA 1HUCB 3H7DA 1QDQA 1K3BB 2Y6EA 1U9XA 3MHHA 1PCIA 4P6EA 1CJLA 6PADA 5JH3A 3N3GA 1ICFA 1JQPA 4WA6A 5CHTA 4ZUXU 1AIMA 1F2BA 2ACTA 3I3TA 4MSXA 3LFYA 2DZZA 4P6GA 1O0EA 2JQFR 4CDEB 2AUXA 2PREA 1PPNA 2NQIA 4YYQA 2GFOA 3BC3A 3HD3A 3KSEA 3KFQA 1EWPA 1BP4A 5JA7A 3RVXA 8PCHA 1VJVA 1NPZA 3OVXA 3OF9A 3P5VA 3QT4A 1YALA 3KKUA 2E02A 2R9FA 4AXLA 2R9CA 3QJ3A 3RVVA 1AU0A 1MS6A 3H8BA 1PPOA 2WBFX 4QH6A 2FRAA 2B1NA 1DF0A 2E03A 5J94A 2DJFB 3B79A 2DC8A 4G54A 1Y08A 4MZSA 1GMYA 1AU4A 1QXPA 4CDFB 4PI3A 2ATOA 2AYOA 3WXEA 1CV8A 5CVNB 1KHPA 4X6JA 4RY2A 1GECE 2OZ2A 1PPDA 1YK8A 5K16A 3QSDA 2FO5A 1SNKA 3CH2X 1CSBB 2G6DA 2FYEA 2C0YA 4BSQA 2XU3A 4XUIA 4Q8HA 1TLOA 3C9EA 3K24A 5FPWA 4BS5A 1U9VA 3AI8A 2YJCA 3PDFA 5CVMA 1GLOA 3BCNA 3I06A 5EF4A 4W4UA 3CBKA 3OF8A 3BPFA 4QRXA 2FUDA 2R9OA 2R6NA 3WXFA 4QRGA 4PP2E 1CVZA 2CB5A 2DC9A 1NB3A 4K7CA 4CDDB 1IWDA 3KWBX 1F29A 3MORA 4X6IA 2DJGB 1SP4B 1EF7A 1QOLA 3ERVA 4BQVA 1PIPA 1KFUL 4YYWA 2VHSA 1MEMA 3K8UA 4PP1A 1A6RA 2YJ2A 2AU1A 2DCAA 1BQIA 1KHQA 2HXZA 2XU4A 2P86A 4AXMA 4YYUA 4N79A 1FH0A 2F7DA 4FK5A 1S4VA 2G8JA 1CS8A 4FJCA 2P0RA 2DCCA 3IHPA 5A24A 2DC7A 1PXVA 1U9QX 3BOWA 4CDCB 5CVOB 2IPPB 2BDLA 2FQ9A 3V6CA 5F02A 3N3KA 3PNRA 3F5VA 1YT7A 3PBHA 3MHSA 2PBHA 4Q8GA 4PADA 1KXRA 4QRVA 3CBJA 3S3QA 1NLJA 1ZIVA 1ATKA 2E01A 3F75A 1EWMA 1MHWA 4XR7A 2GHUA 5PADA 4N4ZA 1THEA 4DMXA 1U9WA 1CPJA 3TNXA 2YJBA 2DZYA 2VHFA 3KWZA 3ZUAA 2AVWA 3OVZA 3H6SA 4YYSA 4YYRA 3P5WA 1VSNA 2R9NA 1Q6KA 3GCBA 3IMAA 2OP3A 3RVWA 1Y4HA 3N4CA 1GCBA 2Y5BA 3S3RA 1PBHA 2BDZA 1DEUA 1NL6A 3M99A 9PAPA 4BPVA 4CZWA 2PNSA 3LXSA 3OISA 3IOQA 1TL9A 2B1MA 1MDWA 1QMYA 3IEJA 3D6SA 4OELA 1ME4A 1EWLA 1CQDA 3H89A 2DCDA 1YK7A 1U5IA 3U8EA 1M6DA 1AU2A 3E1ZB 2IBIA 4BS6A 2NQGA 2FRQA 3BPMA 3H8CA 2HHNA 4DMYA 1PPPA 1NB5A 2F1GA 3P5XA 2AUZA 2ARYA 1AYUA 2NQDB 4OEMA 3MTNA 1CTEA 1YVBA 4FIPA 1BY8A 3CH3X 5CHVA 1MEGA 4QBBA 2G8EA 2HD5A 1TU6A 2O6XA 1POPA 2H7JA 1STFE 2YJ9A 1PE6A 2YJ8A 4X6HA 1F2CA 2AYNA 1XKGA 1NQCA 3BWKA 2HH5A 4KLBA 2OULA 4HWYA 5EGWA 2NQAA 3KX1A 3KW9A 4I05A 2DC6A 3P5UA 3O0UA 2FTDA 3HHAA 3PW3A 4W5CA 2P7UA 3DF0A 2XU1A 4N8WA 2G7YA 1MIRA 1AECA 2JQGR 2CIOA 3NHEA 4MZOA 3USVA 4YYVA 3HWNA 3IV2A 1PADA 4I07A 2E00A 1BGOA 4I04A 3K9MA 3V6EA 7PCKA 3O1GA 1AU3A 2AS8A 4YVAA 3HHIA 2FT2A 1ITOA 2R9MA 3IUTA 1EWOA 1CB5A 4YV8A 3WXGA 1X9YA
chains in the Genus database with same CATH superfamily
1AYVA 5JZEA 1ME3A 1F2AA 2AIMA 4W5BA 2XU5A 1KFXL 1AYWA 2PADA 1ZCMA 2DCBA 1HUCB 3H7DA 1QDQA 4M0WA 3W31A 1K3BB 2Y6EA 1U9XA 3MHHA 1PCIA 4P6EA 1CJLA 3ZNHA 6PADA 3PHWA 5JH3A 3N3GA 1ICFA 1JQPA 4WA6A 5CHTA 4ZUXU 1AIMA 1F2BA 2ACTA 3I3TA 4MSXA 3LFYA 1YZBA 2DZZA 4RKXA 4P6GA 1O0EA 3PRMA 2JQFR 4CDEB 2AUXA 2PREA 1PPNA 2NQIA 4YYQA 2GFOA 3BC3A 3HD3A 3KSEA 3KFQA 1EWPA 1BP4A 5JA7A 3RVXA 8PCHA 1VJVA 1NPZA 3OVXA 3OF9A 3P5VA 3QT4A 1YALA 3TMPA 3KKUA 2E02A 2R9FA 4AXLA 2R9CA 4BOUA 3QJ3A 4GUAA 3RVVA 1AU0A 1MS6A 3H8BA 1PPOA 2WBFX 4QH6A 2BU3A 2FRAA 2B1NA 1DF0A 2E03A 5J94A 2DJFB 3B79A 2DC8A 2J7QA 4G54A 1Y08A 4MZSA 1GMYA 1AU4A 1QXPA 4CDFB 4HXDB 5EZQA 4PT5A 4PI3A 2ATOA 2AYOA 3WXEA 1CV8A 5EZSA 5CVNB 1KHPA 4X6JA 4RY2A 3PT2A 1GECE 2OZ2A 1PPDA 1YK8A 5K16A 3QSDA 2FO5A 1SNKA 3CH2X 1CSBB 3OQCA 4RF0A 2G6DA 2FYEA 2C0YA 4BSQA 2XU3A 4XUIA 4Q8HA 1TLOA 2JTCA 3C9EA 3K24A 5FPWA 4BS5A 1U9VA 2J7QC 3AI8A 3PDFA 2YJCA 5CVMA 1GLOA 3BCNA 3I06A 5EF4A 4W4UA 3CBKA 3OF8A 4IP3A 3BPFA 4QRXA 2FUDA 2R9OA 1PVJA 2R6NA 3WXFA 4QRGA 4PP2E 4D8BA 1CVZA 2CB5A 2DC9A 4D8IA 4R3DA 2HWKA 1NB3A 4K7CA 4CDDB 1DKIA 1IWDA 3KWBX 1F29A 3MORA 4X6IA 3MTVA 2DJGB 1SP4B 1EF7A 1QOLA 3ERVA 4BQVA 1PIPA 1KFUL 4YYWA 2VHSA 4ZTBA 2AGAA 1MEMA 3K8UA 4PP1A 1A6RA 2YJ2A 2AU1A 4OVZA 2DCAA 1BQIA 1KHQA 2HXZA 2XU4A 2P86A 4AXMA 3PSEA 4YYUA 4N79A 4BOQA 1FH0A 2F7DA 4FK5A 1S4VA 2G8JA 1CS8A 4FJCA 2P0RA 2DCCA 3IHPA 5A24A 2DC7A 3O65A 1PXVA 1U9QX 3BOWA 4OVZB 4CDCB 5CVOB 2IPPB 2BDLA 2FQ9A 3V6CA 5F02A 4MM3B 3N3KA 4IUMA 3PNRA 3F5VA 1YT7A 3PBHA 3MHSA 2PBHA 4Q8GA 4PADA 3PRPA 2JRIA 1KXRA 4QRVA 3CBJA 3S3QA 1NLJA 1ZIVA 3MJ5A 1ATKA 2E01A 3F75A 1EWMA 1MHWA 4XR7A 2GHUA 5PADA 4N4ZA 1THEA 3C0RA 4DMXA 1U9WA 1CPJA 4MI7A 2DOSA 3TNXA 4OW0A 2YJBA 5E6JA 2DZYA 2VHFA 3KWZA 3ZUAA 4P16A 2AVWA 3OVZA 3H6SA 4YYSA 4YYRA 3P5WA 1VSNA 2R9NA 1Q6KA 3GCBA 3IMAA 2OP3A 3RVWA 1Y4HA 3N4CA 1GCBA 2Y5BA 3W30A 3S3RA 1PBHA 2BDZA 5KO3A 1DEUA 1NL6A 2Z84A 3M99A 9PAPA 4BPVA 4CZWA 2PNSA 3LXSA 3PHUA 4D8EA 3OISA 3IOQA 1TL9A 3MP2A 2B1MA 1MDWA 1QMYA 3IEJA 3D6SA 4OELA 1ME4A 1EWLA 1CQDA 3H89A 2DCDA 4BOSA 1YK7A 1U5IA 3TRKA 3U8EA 1M6DA 3IFUA 1AU2A 3E1ZB 2IBIA 4BS6A 4A5UA 2NQGA 2FRQA 3BPMA 3H8CA 2HHNA 1UKFA 4DMYA 1PPPA 1NB5A 2UZJA 2F1GA 3P5XA 4BOZA 2AUZA 2ARYA 2FE8A 1AYUA 2NQDB 4RF1A 4OEMA 2BTWA 3MTNA 1CTEA 1YVBA 4FIPA 1BY8A 3CH3X 5CHVA 1MEGA 4QBBA 3BB7A 2G8EA 2HD5A 1TU6A 2O6XA 1POPA 2H7JA 1STFE 2YJ9A 1PE6A 2YJ8A 4X6HA 1F2CA 2AYNA 4BOPA 3RNVA 3E9SA 1XKGA 1NQCA 3BWKA 2HH5A 4KLBA 2OULA 2BTWB 4HWYA 5EGWA 3BBAA 3B21A 4WURA 2NQAA 3KX1A 3KW9A 4I05A 2DC6A 3P5UA 3O0UA 2FTDA 3HHAA 3PW3A 4W5CA 2P7UA 3DF0A 2XU1A 4N8WA 2G7YA 1MIRA 1AECA 2JQGR 2CIOA 3NHEA 4MZOA 3USVA 4YYVA 3HWNA 3IV2A 1PADA 4I07A 2E00A 1BGOA 4I04A 3K9MA 3V6EA 7PCKA 3O1GA 1AU3A 2AS8A 4YVAA 3HHIA 2FT2A 4REZA 1ITOA 2R9MA 3IUTA 1EWOA 1CB5A 4YV8A 4XZXA 3WXGA 3PHXA 4RNAA 1X9YA 3BY4A
chains in the Genus database with same CATH topology
1AYVA 1ME3A 1F2AA 2AIMA 4W5BA 2XU5A 1KFXL 1AYWA 2PADA 1ZCMA 2DCBA 1HUCB 3H7DA 1QDQA 4NV7A 1K3BB 2Y6EA 1U9XA 3MHHA 1PCIA 4P6EA 1CJLA 6PADA 5JH3A 3N3GA 1ICFA 1JQPA 4WA6A 5CHTA 4ZUXU 1AIMA 1F2BA 2ACTA 2VFCA 3I3TA 4MSXA 3LFYA 2DZZA 4P6GA 1O0EA 2JQFR 4CDEB 2AUXA 2PREA 1PPNA 2NQIA 4YYQA 2GFOA 3BC3A 3HD3A 3KSEA 3KFQA 1EWPA 1BP4A 5JA7A 3RVXA 8PCHA 1VJVA 1NPZA 3OVXA 1W5RA 3OF9A 3P5VA 3QT4A 4C5PA 1YALA 3KKUA 2VFBA 2E02A 2R9FA 4AXLA 2R9CA 3QJ3A 3RVVA 1AU0A 1MS6A 3H8BA 1PPOA 2WBFX 4QH6A 2FRAA 2BSZA 2B1NA 1DF0A 2E03A 5J94A 2DJFB 3B79A 2DC8A 4G54A 1Y08A 4MZSA 1GMYA 1GX3A 1AU4A 1QXPA 4CDFB 4PI3A 2ATOA 2AYOA 3WXEA 1CV8A 5CVNB 1KHPA 4X6JA 4RY2A 1GECE 2OZ2A 1PPDA 1YK8A 1E2TA 5K16A 3QSDA 2FO5A 1SNKA 3CH2X 1CSBB 2G6DA 2FYEA 2C0YA 4BSQA 2XU3A 4XUIA 4Q8HA 1TLOA 3C9EA 3K24A 5FPWA 4BS5A 1U9VA 3AI8A 3PDFA 2YJCA 5CVMA 1GLOA 3BCNA 3I06A 5EF4A 4W4UA 3CBKA 3OF8A 3BPFA 4QRXA 2FUDA 2R9OA 2R6NA 3WXFA 4QRGA 4PP2E 1CVZA 2CB5A 2DC9A 3LTWA 1NB3A 4K7CA 4CDDB 4GUZA 1IWDA 3KWBX 1F29A 3MORA 4X6IA 2DJGB 1SP4B 1EF7A 1QOLA 3ERVA 4BQVA 1PIPA 1KFUL 4YYWA 2VHSA 1W6FA 1MEMA 3K8UA 3D9WA 4PP1A 1A6RA 2YJ2A 2AU1A 2DCAA 1BQIA 1KHQA 2HXZA 2XU4A 2P86A 4AXMA 4YYUA 4N79A 1FH0A 2F7DA 4FK5A 1S4VA 2G8JA 1CS8A 4FJCA 2P0RA 2DCCA 3IHPA 5A24A 2DC7A 1PXVA 1U9QX 3BOWA 4CDCB 5CVOB 2IPPB 2BDLA 2FQ9A 3V6CA 5F02A 3N3KA 3PNRA 3F5VA 1YT7A 3PBHA 3MHSA 2PBHA 4Q8GA 4PADA 1KXRA 4QRVA 3CBJA 3S3QA 1NLJA 1ZIVA 1ATKA 2E01A 3F75A 1EWMA 1MHWA 4XR7A 2GHUA 5PADA 4N4ZA 1THEA 4DMXA 1U9WA 1CPJA 3TNXA 2YJBA 2DZYA 2VHFA 3KWZA 3ZUAA 2AVWA 3OVZA 3H6SA 4YYSA 4YYRA 3P5WA 1VSNA 2R9NA 1Q6KA 3GCBA 3IMAA 2OP3A 3RVWA 1Y4HA 3N4CA 1GCBA 2Y5BA 3S3RA 1PBHA 2BDZA 1DEUA 1NL6A 3M99A 9PAPA 4BPVA 4CZWA 2PNSA 3LXSA 3OISA 3IOQA 1TL9A 2B1MA 1MDWA 1QMYA 3IEJA 3D6SA 4OELA 1ME4A 1EWLA 1CQDA 3H89A 2DCDA 1YK7A 1U5IA 3U8EA 1M6DA 1AU2A 3E1ZB 2IBIA 4BS6A 2NQGA 2FRQA 3BPMA 3H8CA 2HHNA 4DMYA 1PPPA 1NB5A 2F1GA 3P5XA 2AUZA 2ARYA 1AYUA 2NQDB 4OEMA 3MTNA 1CTEA 1W4TA 1YVBA 1BY8A 3CH3X 4FIPA 5CHVA 4B55A 1MEGA 4QBBA 2G8EA 2HD5A 1TU6A 2O6XA 1POPA 2H7JA 1STFE 2YJ9A 1PE6A 2YJ8A 4X6HA 1F2CA 2AYNA 1XKGA 1NQCA 3BWKA 2HH5A 4KLBA 2OULA 4NV8A 4HWYA 5EGWA 2NQAA 3KX1A 3KW9A 4I05A 2DC6A 3P5UA 3O0UA 2FTDA 3HHAA 3PW3A 4W5CA 2P7UA 3DF0A 2XU1A 4N8WA 2G7YA 1MIRA 1AECA 2JQGR 2CIOA 3NHEA 4MZOA 3USVA 4YYVA 3HWNA 3IV2A 1PADA 4I07A 2E00A 1BGOA 4I04A 3K9MA 3V6EA 7PCKA 3O1GA 1AU3A 2AS8A 4YVAA 3HHIA 2FT2A 4BGFA 1ITOA 2R9MA 3IUTA 1EWOA 1CB5A 4YV8A 3WXGA 1X9YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AYV A;  1ME3 A;  1F2A A;  2AIM A;  4W5B A;  2XU5 A;  1KFX L;  1AYW A;  2PAD A;  1ZCM A;  2DCB A;  1HUC B;  3H7D A;  1QDQ A;  1K3B B;  2Y6E A;  1U9X A;  3MHH A;  1PCI A;  4P6E A;  1CJL A;  6PAD A;  5JH3 A;  3N3G A;  1ICF A;  1JQP A;  4WA6 A;  5CHT A;  4ZUX U;  1AIM A;  1F2B A;  2ACT A;  3I3T A;  4MSX A;  3LFY A;  2DZZ A;  4P6G A;  1O0E A;  2JQF R;  4CDE B;  2AUX A;  2PRE A;  1PPN A;  2NQI A;  4YYQ A;  2GFO A;  3BC3 A;  3HD3 A;  3KSE A;  3KFQ A;  1EWP A;  1BP4 A;  5JA7 A;  3RVX A;  8PCH A;  1VJV A;  1NPZ A;  3OVX A;  3OF9 A;  3P5V A;  3QT4 A;  1YAL A;  3KKU A;  2E02 A;  2R9F A;  4AXL A;  2R9C A;  3QJ3 A;  3RVV A;  1AU0 A;  1MS6 A;  3H8B A;  1PPO A;  2WBF X;  4QH6 A;  2FRA A;  2B1N A;  1DF0 A;  2E03 A;  5J94 A;  2DJF B;  3B79 A;  2DC8 A;  4G54 A;  1Y08 A;  4MZS A;  1GMY A;  1AU4 A;  1QXP A;  4CDF B;  4PI3 A;  2ATO A;  2AYO A;  3WXE A;  1CV8 A;  5CVN B;  1KHP A;  4X6J A;  4RY2 A;  1GEC E;  2OZ2 A;  1PPD A;  1YK8 A;  5K16 A;  3QSD A;  2FO5 A;  1SNK A;  3CH2 X;  1CSB B;  2G6D A;  2FYE A;  2C0Y A;  4BSQ A;  2XU3 A;  4XUI A;  4Q8H A;  1TLO A;  3C9E A;  3K24 A;  5FPW A;  4BS5 A;  1U9V A;  3AI8 A;  2YJC A;  3PDF A;  5CVM A;  1GLO A;  3BCN A;  3I06 A;  5EF4 A;  4W4U A;  3CBK A;  3OF8 A;  3BPF A;  4QRX A;  2FUD A;  2R9O A;  2R6N A;  3WXF A;  4QRG A;  4PP2 E;  1CVZ A;  2CB5 A;  2DC9 A;  1NB3 A;  4K7C A;  4CDD B;  1IWD A;  3KWB X;  1F29 A;  3MOR A;  4X6I A;  2DJG B;  1SP4 B;  1EF7 A;  1QOL A;  3ERV A;  4BQV A;  1PIP A;  1KFU L;  4YYW A;  2VHS A;  1MEM A;  3K8U A;  4PP1 A;  1A6R A;  2YJ2 A;  2AU1 A;  2DCA A;  1BQI A;  1KHQ A;  2HXZ A;  2XU4 A;  2P86 A;  4AXM A;  4YYU A;  4N79 A;  1FH0 A;  2F7D A;  4FK5 A;  1S4V A;  2G8J A;  1CS8 A;  4FJC A;  2P0R A;  2DCC A;  3IHP A;  5A24 A;  2DC7 A;  1PXV A;  1U9Q X;  3BOW A;  4CDC B;  5CVO B;  2IPP B;  2BDL A;  2FQ9 A;  3V6C A;  5F02 A;  3N3K A;  3PNR A;  3F5V A;  1YT7 A;  3PBH A;  3MHS A;  2PBH A;  4Q8G A;  4PAD A;  1KXR A;  4QRV A;  3CBJ A;  3S3Q A;  1NLJ A;  1ZIV A;  1ATK A;  2E01 A;  3F75 A;  1EWM A;  1MHW A;  4XR7 A;  2GHU A;  5PAD A;  4N4Z A;  1THE A;  4DMX A;  1U9W A;  1CPJ A;  3TNX A;  2YJB A;  2DZY A;  2VHF A;  3KWZ A;  3ZUA A;  2AVW A;  3OVZ A;  3H6S A;  4YYS A;  4YYR A;  3P5W A;  1VSN A;  2R9N A;  1Q6K A;  3GCB A;  3IMA A;  2OP3 A;  3RVW A;  1Y4H A;  3N4C A;  1GCB A;  2Y5B A;  3S3R A;  1PBH A;  2BDZ A;  1DEU A;  1NL6 A;  3M99 A;  9PAP A;  4BPV A;  4CZW A;  2PNS A;  3LXS A;  3OIS A;  3IOQ A;  1TL9 A;  2B1M A;  1MDW A;  1QMY A;  3IEJ A;  3D6S A;  4OEL A;  1ME4 A;  1EWL A;  1CQD A;  3H89 A;  2DCD A;  1YK7 A;  1U5I A;  3U8E A;  1M6D A;  1AU2 A;  3E1Z B;  2IBI A;  4BS6 A;  2NQG A;  2FRQ A;  3BPM A;  3H8C A;  2HHN A;  4DMY A;  1PPP A;  1NB5 A;  2F1G A;  3P5X A;  2AUZ A;  2ARY A;  1AYU A;  2NQD B;  4OEM A;  3MTN A;  1CTE A;  1YVB A;  4FIP A;  1BY8 A;  3CH3 X;  5CHV A;  1MEG A;  4QBB A;  2G8E A;  2HD5 A;  1TU6 A;  2O6X A;  1POP A;  2H7J A;  1STF E;  2YJ9 A;  1PE6 A;  2YJ8 A;  4X6H A;  1F2C A;  2AYN A;  1XKG A;  1NQC A;  3BWK A;  2HH5 A;  4KLB A;  2OUL A;  4HWY A;  5EGW A;  2NQA A;  3KX1 A;  3KW9 A;  4I05 A;  2DC6 A;  3P5U A;  3O0U A;  2FTD A;  3HHA A;  3PW3 A;  4W5C A;  2P7U A;  3DF0 A;  2XU1 A;  4N8W A;  2G7Y A;  1MIR A;  1AEC A;  2JQG R;  2CIO A;  3NHE A;  4MZO A;  3USV A;  4YYV A;  3HWN A;  3IV2 A;  1PAD A;  4I07 A;  2E00 A;  1BGO A;  4I04 A;  3K9M A;  3V6E A;  7PCK A;  3O1G A;  1AU3 A;  2AS8 A;  4YVA A;  3HHI A;  2FT2 A;  1ITO A;  2R9M A;  3IUT A;  1EWO A;  1CB5 A;  4YV8 A;  3WXG A;  1X9Y A; 
#chains in the Genus database with same CATH topology
 1AYV A;  5JZE A;  1ME3 A;  1F2A A;  2AIM A;  4W5B A;  2XU5 A;  1KFX L;  1AYW A;  2PAD A;  1ZCM A;  2DCB A;  1HUC B;  3H7D A;  1QDQ A;  4M0W A;  3W31 A;  1K3B B;  2Y6E A;  1U9X A;  3MHH A;  1PCI A;  4P6E A;  1CJL A;  3ZNH A;  6PAD A;  3PHW A;  5JH3 A;  3N3G A;  1ICF A;  1JQP A;  4WA6 A;  5CHT A;  4ZUX U;  1AIM A;  1F2B A;  2ACT A;  3I3T A;  4MSX A;  3LFY A;  1YZB A;  2DZZ A;  4RKX A;  4P6G A;  1O0E A;  3PRM A;  2JQF R;  4CDE B;  2AUX A;  2PRE A;  1PPN A;  2NQI A;  4YYQ A;  2GFO A;  3BC3 A;  3HD3 A;  3KSE A;  3KFQ A;  1EWP A;  1BP4 A;  5JA7 A;  3RVX A;  8PCH A;  1VJV A;  1NPZ A;  3OVX A;  3OF9 A;  3P5V A;  3QT4 A;  1YAL A;  3TMP A;  3KKU A;  2E02 A;  2R9F A;  4AXL A;  2R9C A;  4BOU A;  3QJ3 A;  4GUA A;  3RVV A;  1AU0 A;  1MS6 A;  3H8B A;  1PPO A;  2WBF X;  4QH6 A;  2BU3 A;  2FRA A;  2B1N A;  1DF0 A;  2E03 A;  5J94 A;  2DJF B;  3B79 A;  2DC8 A;  2J7Q A;  4G54 A;  1Y08 A;  4MZS A;  1GMY A;  1AU4 A;  1QXP A;  4CDF B;  4HXD B;  5EZQ A;  4PT5 A;  4PI3 A;  2ATO A;  2AYO A;  3WXE A;  1CV8 A;  5EZS A;  5CVN B;  1KHP A;  4X6J A;  4RY2 A;  3PT2 A;  1GEC E;  2OZ2 A;  1PPD A;  1YK8 A;  5K16 A;  3QSD A;  2FO5 A;  1SNK A;  3CH2 X;  1CSB B;  3OQC A;  4RF0 A;  2G6D A;  2FYE A;  2C0Y A;  4BSQ A;  2XU3 A;  4XUI A;  4Q8H A;  1TLO A;  2JTC A;  3C9E A;  3K24 A;  5FPW A;  4BS5 A;  1U9V A;  2J7Q C;  3AI8 A;  3PDF A;  2YJC A;  5CVM A;  1GLO A;  3BCN A;  3I06 A;  5EF4 A;  4W4U A;  3CBK A;  3OF8 A;  4IP3 A;  3BPF A;  4QRX A;  2FUD A;  2R9O A;  1PVJ A;  2R6N A;  3WXF A;  4QRG A;  4PP2 E;  4D8B A;  1CVZ A;  2CB5 A;  2DC9 A;  4D8I A;  4R3D A;  2HWK A;  1NB3 A;  4K7C A;  4CDD B;  1DKI A;  1IWD A;  3KWB X;  1F29 A;  3MOR A;  4X6I A;  3MTV A;  2DJG B;  1SP4 B;  1EF7 A;  1QOL A;  3ERV A;  4BQV A;  1PIP A;  1KFU L;  4YYW A;  2VHS A;  4ZTB A;  2AGA A;  1MEM A;  3K8U A;  4PP1 A;  1A6R A;  2YJ2 A;  2AU1 A;  4OVZ A;  2DCA A;  1BQI A;  1KHQ A;  2HXZ A;  2XU4 A;  2P86 A;  4AXM A;  3PSE A;  4YYU A;  4N79 A;  4BOQ A;  1FH0 A;  2F7D A;  4FK5 A;  1S4V A;  2G8J A;  1CS8 A;  4FJC A;  2P0R A;  2DCC A;  3IHP A;  5A24 A;  2DC7 A;  3O65 A;  1PXV A;  1U9Q X;  3BOW A;  4OVZ B;  4CDC B;  5CVO B;  2IPP B;  2BDL A;  2FQ9 A;  3V6C A;  5F02 A;  4MM3 B;  3N3K A;  4IUM A;  3PNR A;  3F5V A;  1YT7 A;  3PBH A;  3MHS A;  2PBH A;  4Q8G A;  4PAD A;  3PRP A;  2JRI A;  1KXR A;  4QRV A;  3CBJ A;  3S3Q A;  1NLJ A;  1ZIV A;  3MJ5 A;  1ATK A;  2E01 A;  3F75 A;  1EWM A;  1MHW A;  4XR7 A;  2GHU A;  5PAD A;  4N4Z A;  1THE A;  3C0R A;  4DMX A;  1U9W A;  1CPJ A;  4MI7 A;  2DOS A;  3TNX A;  4OW0 A;  2YJB A;  5E6J A;  2DZY A;  2VHF A;  3KWZ A;  3ZUA A;  4P16 A;  2AVW A;  3OVZ A;  3H6S A;  4YYS A;  4YYR A;  3P5W A;  1VSN A;  2R9N A;  1Q6K A;  3GCB A;  3IMA A;  2OP3 A;  3RVW A;  1Y4H A;  3N4C A;  1GCB A;  2Y5B A;  3W30 A;  3S3R A;  1PBH A;  2BDZ A;  5KO3 A;  1DEU A;  1NL6 A;  2Z84 A;  3M99 A;  9PAP A;  4BPV A;  4CZW A;  2PNS A;  3LXS A;  3PHU A;  4D8E A;  3OIS A;  3IOQ A;  1TL9 A;  3MP2 A;  2B1M A;  1MDW A;  1QMY A;  3IEJ A;  3D6S A;  4OEL A;  1ME4 A;  1EWL A;  1CQD A;  3H89 A;  2DCD A;  4BOS A;  1YK7 A;  1U5I A;  3TRK A;  3U8E A;  1M6D A;  3IFU A;  1AU2 A;  3E1Z B;  2IBI A;  4BS6 A;  4A5U A;  2NQG A;  2FRQ A;  3BPM A;  3H8C A;  2HHN A;  1UKF A;  4DMY A;  1PPP A;  1NB5 A;  2UZJ A;  2F1G A;  3P5X A;  4BOZ A;  2AUZ A;  2ARY A;  2FE8 A;  1AYU A;  2NQD B;  4RF1 A;  4OEM A;  2BTW A;  3MTN A;  1CTE A;  1YVB A;  4FIP A;  1BY8 A;  3CH3 X;  5CHV A;  1MEG A;  4QBB A;  3BB7 A;  2G8E A;  2HD5 A;  1TU6 A;  2O6X A;  1POP A;  2H7J A;  1STF E;  2YJ9 A;  1PE6 A;  2YJ8 A;  4X6H A;  1F2C A;  2AYN A;  4BOP A;  3RNV A;  3E9S A;  1XKG A;  1NQC A;  3BWK A;  2HH5 A;  4KLB A;  2OUL A;  2BTW B;  4HWY A;  5EGW A;  3BBA A;  3B21 A;  4WUR A;  2NQA A;  3KX1 A;  3KW9 A;  4I05 A;  2DC6 A;  3P5U A;  3O0U A;  2FTD A;  3HHA A;  3PW3 A;  4W5C A;  2P7U A;  3DF0 A;  2XU1 A;  4N8W A;  2G7Y A;  1MIR A;  1AEC A;  2JQG R;  2CIO A;  3NHE A;  4MZO A;  3USV A;  4YYV A;  3HWN A;  3IV2 A;  1PAD A;  4I07 A;  2E00 A;  1BGO A;  4I04 A;  3K9M A;  3V6E A;  7PCK A;  3O1G A;  1AU3 A;  2AS8 A;  4YVA A;  3HHI A;  2FT2 A;  4REZ A;  1ITO A;  2R9M A;  3IUT A;  1EWO A;  1CB5 A;  4YV8 A;  4XZX A;  3WXG A;  3PHX A;  4RNA A;  1X9Y A;  3BY4 A; 
#chains in the Genus database with same CATH homology
 1AYV A;  1ME3 A;  1F2A A;  2AIM A;  4W5B A;  2XU5 A;  1KFX L;  1AYW A;  2PAD A;  1ZCM A;  2DCB A;  1HUC B;  3H7D A;  1QDQ A;  4NV7 A;  1K3B B;  2Y6E A;  1U9X A;  3MHH A;  1PCI A;  4P6E A;  1CJL A;  6PAD A;  5JH3 A;  3N3G A;  1ICF A;  1JQP A;  4WA6 A;  5CHT A;  4ZUX U;  1AIM A;  1F2B A;  2ACT A;  2VFC A;  3I3T A;  4MSX A;  3LFY A;  2DZZ A;  4P6G A;  1O0E A;  2JQF R;  4CDE B;  2AUX A;  2PRE A;  1PPN A;  2NQI A;  4YYQ A;  2GFO A;  3BC3 A;  3HD3 A;  3KSE A;  3KFQ A;  1EWP A;  1BP4 A;  5JA7 A;  3RVX A;  8PCH A;  1VJV A;  1NPZ A;  3OVX A;  1W5R A;  3OF9 A;  3P5V A;  3QT4 A;  4C5P A;  1YAL A;  3KKU A;  2VFB A;  2E02 A;  2R9F A;  4AXL A;  2R9C A;  3QJ3 A;  3RVV A;  1AU0 A;  1MS6 A;  3H8B A;  1PPO A;  2WBF X;  4QH6 A;  2FRA A;  2BSZ A;  2B1N A;  1DF0 A;  2E03 A;  5J94 A;  2DJF B;  3B79 A;  2DC8 A;  4G54 A;  1Y08 A;  4MZS A;  1GMY A;  1GX3 A;  1AU4 A;  1QXP A;  4CDF B;  4PI3 A;  2ATO A;  2AYO A;  3WXE A;  1CV8 A;  5CVN B;  1KHP A;  4X6J A;  4RY2 A;  1GEC E;  2OZ2 A;  1PPD A;  1YK8 A;  1E2T A;  5K16 A;  3QSD A;  2FO5 A;  1SNK A;  3CH2 X;  1CSB B;  2G6D A;  2FYE A;  2C0Y A;  4BSQ A;  2XU3 A;  4XUI A;  4Q8H A;  1TLO A;  3C9E A;  3K24 A;  5FPW A;  4BS5 A;  1U9V A;  3AI8 A;  3PDF A;  2YJC A;  5CVM A;  1GLO A;  3BCN A;  3I06 A;  5EF4 A;  4W4U A;  3CBK A;  3OF8 A;  3BPF A;  4QRX A;  2FUD A;  2R9O A;  2R6N A;  3WXF A;  4QRG A;  4PP2 E;  1CVZ A;  2CB5 A;  2DC9 A;  3LTW A;  1NB3 A;  4K7C A;  4CDD B;  4GUZ A;  1IWD A;  3KWB X;  1F29 A;  3MOR A;  4X6I A;  2DJG B;  1SP4 B;  1EF7 A;  1QOL A;  3ERV A;  4BQV A;  1PIP A;  1KFU L;  4YYW A;  2VHS A;  1W6F A;  1MEM A;  3K8U A;  3D9W A;  4PP1 A;  1A6R A;  2YJ2 A;  2AU1 A;  2DCA A;  1BQI A;  1KHQ A;  2HXZ A;  2XU4 A;  2P86 A;  4AXM A;  4YYU A;  4N79 A;  1FH0 A;  2F7D A;  4FK5 A;  1S4V A;  2G8J A;  1CS8 A;  4FJC A;  2P0R A;  2DCC A;  3IHP A;  5A24 A;  2DC7 A;  1PXV A;  1U9Q X;  3BOW A;  4CDC B;  5CVO B;  2IPP B;  2BDL A;  2FQ9 A;  3V6C A;  5F02 A;  3N3K A;  3PNR A;  3F5V A;  1YT7 A;  3PBH A;  3MHS A;  2PBH A;  4Q8G A;  4PAD A;  1KXR A;  4QRV A;  3CBJ A;  3S3Q A;  1NLJ A;  1ZIV A;  1ATK A;  2E01 A;  3F75 A;  1EWM A;  1MHW A;  4XR7 A;  2GHU A;  5PAD A;  4N4Z A;  1THE A;  4DMX A;  1U9W A;  1CPJ A;  3TNX A;  2YJB A;  2DZY A;  2VHF A;  3KWZ A;  3ZUA A;  2AVW A;  3OVZ A;  3H6S A;  4YYS A;  4YYR A;  3P5W A;  1VSN A;  2R9N A;  1Q6K A;  3GCB A;  3IMA A;  2OP3 A;  3RVW A;  1Y4H A;  3N4C A;  1GCB A;  2Y5B A;  3S3R A;  1PBH A;  2BDZ A;  1DEU A;  1NL6 A;  3M99 A;  9PAP A;  4BPV A;  4CZW A;  2PNS A;  3LXS A;  3OIS A;  3IOQ A;  1TL9 A;  2B1M A;  1MDW A;  1QMY A;  3IEJ A;  3D6S A;  4OEL A;  1ME4 A;  1EWL A;  1CQD A;  3H89 A;  2DCD A;  1YK7 A;  1U5I A;  3U8E A;  1M6D A;  1AU2 A;  3E1Z B;  2IBI A;  4BS6 A;  2NQG A;  2FRQ A;  3BPM A;  3H8C A;  2HHN A;  4DMY A;  1PPP A;  1NB5 A;  2F1G A;  3P5X A;  2AUZ A;  2ARY A;  1AYU A;  2NQD B;  4OEM A;  3MTN A;  1CTE A;  1W4T A;  1YVB A;  1BY8 A;  3CH3 X;  4FIP A;  5CHV A;  4B55 A;  1MEG A;  4QBB A;  2G8E A;  2HD5 A;  1TU6 A;  2O6X A;  1POP A;  2H7J A;  1STF E;  2YJ9 A;  1PE6 A;  2YJ8 A;  4X6H A;  1F2C A;  2AYN A;  1XKG A;  1NQC A;  3BWK A;  2HH5 A;  4KLB A;  2OUL A;  4NV8 A;  4HWY A;  5EGW A;  2NQA A;  3KX1 A;  3KW9 A;  4I05 A;  2DC6 A;  3P5U A;  3O0U A;  2FTD A;  3HHA A;  3PW3 A;  4W5C A;  2P7U A;  3DF0 A;  2XU1 A;  4N8W A;  2G7Y A;  1MIR A;  1AEC A;  2JQG R;  2CIO A;  3NHE A;  4MZO A;  3USV A;  4YYV A;  3HWN A;  3IV2 A;  1PAD A;  4I07 A;  2E00 A;  1BGO A;  4I04 A;  3K9M A;  3V6E A;  7PCK A;  3O1G A;  1AU3 A;  2AS8 A;  4YVA A;  3HHI A;  2FT2 A;  4BGF A;  1ITO A;  2R9M A;  3IUT A;  1EWO A;  1CB5 A;  4YV8 A;  3WXG A;  1X9Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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