4QRVA

Crystal structure of i86f mutant of papain
Total Genus 109
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
Knots found
sequence length
316
structure length
301
Chain Sequence
IVGYSQNDLTSTERLIQLFESWMLKHNKIYKNIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSYTTTEVNIPEYVDWRQKGAVTPVKNQGSCGSAWAFSAVSTIESIIKIRTGNLNEYSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYGPNYILIRNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Pro-peptide regulates the substrate specificity and zymogen activation process of papain: A structural and mechanistic insight
rcsb
molecule tags Hydrolase
source organism Carica papaya
molecule keywords Papain
total genus 109
structure length 301
sequence length 316
chains with identical sequence B
other databases KnotProt 2.0: K -31 -31 -31
ec nomenclature ec 3.4.22.2: Papain.
pdb deposition date 2014-07-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
A PF08246 Inhibitor_I29 Cathepsin propeptide inhibitor domain (I29)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 4qrvA00
4I07A 1PXVA 2NQIA 2YJCA 1AYVA 4MZOA 3WXFA 1PBHA 1CV8A 1KFXL 4P6GA 1MIRA 5EF4A 4PP2E 2DCDA 3N4CA 4PP1A 4W5BA 1MDWA 3KWZA 4QH6A 1AU4A 4CDCB 3F75A 1BP4A 2CIOA 4BS6A 4AXLA 1VJVA 2R9NA 1HUCB 1TLOA 2AUZA 3B79A 4YYRA 3WXEA 1Q6KA 2DZZA 1F2CA 3I06A 2BDZA 2DZYA 3OF8A 2FRAA 1VSNA 3IV2A 1ZIVA 1ME4A 2IBIA 4FIPA 1NB5A 4YYQA 4BS5A 1F2BA 4N4ZA 3KWBX 2DJGB 2FTDA 2DCBA 3BPMA 3P5WA 2DC7A 5CVOB 1CVZA 1CPJA 4ZUXU 3HHIA 2E02A 4W5CA 3PW3A 2GFOA 2R6NA 3IOQA 3D6SA 4RY2A 3H7DA 1ATKA 2AS8A 2R9FA 1EWPA 2HXZA 1NLJA 2CB5A 1F2AA 2PBHA 2JQFR 6PADA 3MHHA 5F02A 2XU5A 2P7UA 1S4VA 3N3KA 3K24A 4QBBA 3RVWA 1M6DA 1SP4B 1KFUL 3BPFA 1ICFA 3P5XA 4I04A 1YK8A 3S3QA 3IEJA 3BC3A 3K8UA 1EWMA 3OVZA 1KHQA 3HD3A 3LFYA 2NQGA 3HHAA 1GCBA 3H8BA 1BGOA 3PBHA 4AXMA 1AYUA 5CHTA 1FH0A 2DCCA 1CTEA 2ARYA 1AYWA 1CB5A 1TL9A 2GHUA 1CQDA 2FQ9A 2WBFX 1AECA 1AU2A 2DC8A 4Q8GA 1PE6A 2XU4A 2AVWA 3H8CA 1EWOA 3WXGA 4YV8A 3OF9A 4FJCA 4MSXA 4PADA 4MZSA 3H6SA 4HWYA 1Y08A 4N79A 4DMYA 2OP3A 3RVXA 1XKGA 3IMAA 1PCIA 3KKUA 3PDFA 1AU3A 2R9CA 2O6XA 2HD5A 1CSBB 1NPZA 1AIMA 3IHPA 4Q8HA 2F1GA 2YJBA 1PPPA 1NQCA 1YALA 3ZUAA 3CH3X 1IWDA 3BCNA 4YYWA 1AU0A 3GCBA 1MEMA 2HH5A 1U9WA 4K7CA 1POPA 1U9XA 2B1MA 2E00A 2AU1A 4X6HA 4CDEB 5FPWA 4CZWA 3OISA 1EF7A 2Y6EA 3QSDA 1GMYA 3USVA 1MEGA 4WA6A 2YJ2A 1GECE 4W4UA 1PPDA 2DCAA 2XU3A 5J94A 3E1ZB 4I05A 3O1GA 3C9EA 4KLBA 3CBJA 1Y4HA 3KW9A 1QXPA 1PADA 4CDDB 3IUTA 2NQAA 2DJFB 4X6IA 4PI3A 2G6DA 2DC9A 2HHNA 1MHWA 1EWLA 2OULA 4QRXA 1PPOA 2G8EA 3BOWA 4FK5A 2Y5BA 3K9MA 2R9OA 3CBKA 1U9VA 3S3RA 4BQVA 1DF0A 4BSQA 3LXSA 2AYOA 2FYEA 2AYNA 2C0YA 2DC6A 1JQPA 1DEUA 2B1NA 3CH2X 2ACTA 4OEMA 2FRQA 1TU6A 5JH3A 2FUDA 9PAPA 2BDLA 8PCHA 2PNSA 2NQDB 3U8EA 1U5IA 1MS6A 4XUIA 1SNKA 2FO5A 2E03A 4DMXA 2OZ2A 3MTNA 3KSEA 2YJ8A 3PNRA 1PPNA 2E01A 3TNXA 1THEA 3MORA 1A6RA 4QRGA 3O0UA 3M99A 1CJLA 1BY8A 2G7YA 2PADA 1ITOA 5JA7A 2JQGR 4G54A 3N3GA 5A24A 1O0EA 2VHSA 3P5UA 4QRVA 1KHPA 1KXRA 2P0RA 1CS8A 2PREA 3QT4A 4CDFB 1U9QX 4P6EA 4OELA 2VHFA 1QMYA 4YYUA 3MHSA 1NL6A 2XU1A 5CVMA 3KX1A 3P5VA 2AIMA 3DF0A 2YJ9A 3V6CA 1YVBA 1X9YA 3NHEA 2R9MA 4YYVA 3I3TA 5CVNB 2ATOA 4YYSA 3QJ3A 2FT2A 3V6EA 2IPPB 1K3BB 2H7JA 3OVXA 3ERVA 1QOLA 3BWKA 2F7DA 7PCKA 1YK7A 3AI8A 3F5VA 4BPVA 5CHVA 3KFQA 1STFE 4N8WA 2P86A 2G8JA 1F29A 1QDQA 1ME3A 4XR7A 1PIPA 1ZCMA 4YVAA 1YT7A 5PADA 4X6JA 1GLOA 1NB3A 3HWNA 1BQIA 2AUXA 3RVVA 5K16A 3H89A 5EGWA
chains in the Genus database with same CATH superfamily
4I07A 4BOZA 1PXVA 2NQIA 4BOSA 4RF1A 2YJCA 1AYVA 4MZOA 3WXFA 1PBHA 1CV8A 1KFXL 4P6GA 2AGAA 1MIRA 3PHXA 1UKFA 5EF4A 4PP2E 3ZNHA 2DCDA 3N4CA 4PP1A 4W5BA 1MDWA 3KWZA 4QH6A 1AU4A 4CDCB 3F75A 1BP4A 2CIOA 4M0WA 4BS6A 4AXLA 3MP2A 1VJVA 2R9NA 1HUCB 1TLOA 2AUZA 3B79A 4YYRA 3E9SA 3WXEA 1Q6KA 2DZZA 1F2CA 3I06A 2BDZA 2DZYA 3OF8A 3C0RA 2FRAA 1VSNA 3IV2A 1ZIVA 1ME4A 4P16A 2IBIA 4FIPA 4REZA 1NB5A 4YYQA 3PHWA 4BS5A 1F2BA 3O65A 4N4ZA 3KWBX 2DJGB 2FTDA 2DCBA 3BPMA 3P5WA 2DC7A 5CVOB 1CVZA 3W31A 1CPJA 4ZUXU 3HHIA 2E02A 4W5CA 3PW3A 4D8BA 2GFOA 2R6NA 3IOQA 2J7QC 5JZEA 3D6SA 4RY2A 3H7DA 1ATKA 2AS8A 2R9FA 1EWPA 2HXZA 1NLJA 2CB5A 1F2AA 2PBHA 2JQFR 6PADA 3MHHA 5F02A 4OVZB 2XU5A 2P7UA 1S4VA 3N3KA 3K24A 4QBBA 3RVWA 1M6DA 1SP4B 1KFUL 3BPFA 1ICFA 3P5XA 4I04A 1YK8A 2JRIA 3S3QA 3IEJA 1YZBA 5EZSA 3BC3A 3K8UA 1EWMA 3OVZA 4PT5A 1KHQA 2BTWA 3HD3A 4RNAA 3LFYA 2NQGA 3HHAA 1GCBA 3H8BA 1BGOA 3PBHA 4AXMA 1AYUA 5CHTA 1FH0A 2DCCA 4MM3B 1CTEA 2ARYA 1AYWA 1CB5A 1TL9A 2GHUA 1CQDA 2FQ9A 2WBFX 4D8EA 1AECA 1AU2A 2DC8A 4Q8GA 1PE6A 2XU4A 5KO3A 2AVWA 3H8CA 2UZJA 1EWOA 3WXGA 4YV8A 3OF9A 4FJCA 4MSXA 4PADA 4MZSA 3H6SA 4HWYA 3PRMA 1Y08A 4N79A 4DMYA 2OP3A 3IFUA 1DKIA 3RVXA 1XKGA 3IMAA 1PCIA 3KKUA 1PVJA 3PDFA 1AU3A 2R9CA 5EZQA 2JTCA 2O6XA 2HD5A 1CSBB 1NPZA 1AIMA 3IHPA 4Q8HA 2J7QA 3BB7A 2F1GA 2YJBA 1PPPA 2BU3A 1NQCA 1YALA 3ZUAA 3CH3X 1IWDA 3BCNA 4YYWA 1AU0A 3GCBA 3B21A 1MEMA 2HH5A 1U9WA 4K7CA 1POPA 1U9XA 2B1MA 2E00A 2AU1A 4X6HA 4GUAA 4CDEB 5FPWA 4BOPA 4CZWA 3OISA 1EF7A 2Y6EA 3QSDA 1GMYA 3USVA 1MEGA 4WA6A 2YJ2A 3PHUA 1GECE 4W4UA 1PPDA 2DCAA 2XU3A 5J94A 3E1ZB 4I05A 3W30A 3O1GA 3C9EA 4KLBA 3CBJA 1Y4HA 3KW9A 3BY4A 1QXPA 2DOSA 1PADA 4CDDB 3IUTA 4XZXA 2NQAA 2DJFB 4X6IA 4PI3A 2G6DA 2DC9A 2HHNA 1MHWA 1EWLA 2OULA 4QRXA 1PPOA 2G8EA 3BOWA 4FK5A 2Y5BA 4IP3A 3TRKA 3K9MA 2R9OA 3CBKA 1U9VA 4ZTBA 2FE8A 5E6JA 3S3RA 4BQVA 1DF0A 4BSQA 3LXSA 4MI7A 2AYOA 2FYEA 2AYNA 2C0YA 2DC6A 1JQPA 1DEUA 2B1NA 3CH2X 2ACTA 3MJ5A 4OEMA 3PSEA 2FRQA 1TU6A 5JH3A 2FUDA 9PAPA 2BDLA 8PCHA 2PNSA 2NQDB 3U8EA 1U5IA 1MS6A 4XUIA 1SNKA 2FO5A 2E03A 4DMXA 2OZ2A 3MTNA 3KSEA 2YJ8A 3PNRA 1PPNA 2E01A 3TNXA 4D8IA 1THEA 3MORA 1A6RA 4QRGA 4OVZA 3O0UA 3RNVA 3M99A 3OQCA 1CJLA 1BY8A 2G7YA 2PADA 3TMPA 1ITOA 5JA7A 2JQGR 4G54A 3N3GA 5A24A 1O0EA 2VHSA 3P5UA 4QRVA 1KHPA 1KXRA 2P0RA 3PRPA 4WURA 1CS8A 2BTWB 2PREA 3QT4A 4CDFB 1U9QX 4P6EA 4OELA 2VHFA 1QMYA 4YYUA 3MHSA 1NL6A 2XU1A 5CVMA 2HWKA 3BBAA 4HXDB 3KX1A 3P5VA 2AIMA 4RKXA 3DF0A 4BOUA 2YJ9A 4IUMA 3V6CA 1YVBA 1X9YA 3NHEA 2R9MA 4YYVA 3I3TA 5CVNB 2ATOA 4YYSA 3QJ3A 2FT2A 3V6EA 2IPPB 1K3BB 2H7JA 3OVXA 3ERVA 1QOLA 3BWKA 2F7DA 7PCKA 1YK7A 3AI8A 3F5VA 4BPVA 2Z84A 5CHVA 3PT2A 3KFQA 1STFE 4N8WA 2P86A 4R3DA 2G8JA 1F29A 1QDQA 1ME3A 4XR7A 1PIPA 1ZCMA 4OW0A 4YVAA 1YT7A 5PADA 4X6JA 1GLOA 1NB3A 4RF0A 3MTVA 3HWNA 1BQIA 2AUXA 3RVVA 5K16A 3H89A 4A5UA 4BOQA 5EGWA
chains in the Genus database with same CATH topology
4I07A 1PXVA 2NQIA 2YJCA 4NV7A 1AYVA 4MZOA 3WXFA 1E2TA 1PBHA 1CV8A 1KFXL 4P6GA 1MIRA 5EF4A 4PP2E 2DCDA 3N4CA 4PP1A 4W5BA 1MDWA 3KWZA 4QH6A 1AU4A 4CDCB 3F75A 1BP4A 2CIOA 4BS6A 4AXLA 1VJVA 1W6FA 2R9NA 1HUCB 1TLOA 2AUZA 3B79A 4YYRA 3WXEA 1Q6KA 2DZZA 1F2CA 3I06A 2BDZA 2DZYA 3OF8A 2FRAA 1VSNA 3IV2A 1ZIVA 1ME4A 2IBIA 4FIPA 1NB5A 4YYQA 4BS5A 1F2BA 4N4ZA 3KWBX 2DJGB 2FTDA 2DCBA 4BGFA 3BPMA 3P5WA 2DC7A 5CVOB 1CVZA 1CPJA 4ZUXU 2BSZA 3HHIA 2E02A 2VFCA 4W5CA 3PW3A 2GFOA 2R6NA 3IOQA 3D6SA 4RY2A 3H7DA 1ATKA 2AS8A 2R9FA 1EWPA 2HXZA 1NLJA 2CB5A 1F2AA 2PBHA 2JQFR 6PADA 3MHHA 5F02A 2XU5A 2P7UA 1S4VA 3N3KA 3K24A 4QBBA 3RVWA 1M6DA 1SP4B 1KFUL 3BPFA 1ICFA 3P5XA 4I04A 1YK8A 3S3QA 3IEJA 3BC3A 3K8UA 1EWMA 3OVZA 1KHQA 4B55A 3HD3A 2VFBA 3LFYA 2NQGA 3HHAA 1GCBA 3H8BA 1BGOA 3PBHA 4AXMA 1AYUA 5CHTA 1FH0A 2DCCA 1CTEA 2ARYA 1AYWA 1CB5A 1TL9A 2GHUA 1CQDA 2FQ9A 2WBFX 4GUZA 1AECA 1AU2A 2DC8A 4Q8GA 1PE6A 2XU4A 2AVWA 3H8CA 1GX3A 1EWOA 3WXGA 4YV8A 3OF9A 4FJCA 4MSXA 4PADA 4MZSA 3H6SA 4HWYA 1Y08A 4N79A 4DMYA 2OP3A 3RVXA 1XKGA 3IMAA 1PCIA 3KKUA 3PDFA 1AU3A 2R9CA 2O6XA 2HD5A 1CSBB 1NPZA 3LTWA 1AIMA 3IHPA 4Q8HA 2F1GA 2YJBA 1PPPA 1NQCA 1YALA 3ZUAA 3CH3X 1IWDA 3BCNA 4YYWA 1AU0A 3GCBA 1MEMA 2HH5A 1U9WA 4K7CA 1POPA 1U9XA 2B1MA 2E00A 2AU1A 4X6HA 4CDEB 5FPWA 4CZWA 3OISA 1EF7A 2Y6EA 3QSDA 1GMYA 3USVA 1W4TA 1MEGA 4WA6A 2YJ2A 1GECE 4W4UA 1PPDA 2DCAA 2XU3A 5J94A 3E1ZB 4I05A 3O1GA 3C9EA 4KLBA 3CBJA 1Y4HA 3KW9A 1QXPA 1PADA 4CDDB 3IUTA 2NQAA 2DJFB 4X6IA 4PI3A 2G6DA 2DC9A 2HHNA 1MHWA 1EWLA 2OULA 4QRXA 1PPOA 2G8EA 3BOWA 4FK5A 2Y5BA 3K9MA 2R9OA 3CBKA 1U9VA 3S3RA 4BQVA 1DF0A 4BSQA 3LXSA 2AYOA 2FYEA 2AYNA 2C0YA 2DC6A 1JQPA 1DEUA 2B1NA 3CH2X 2ACTA 4OEMA 2FRQA 1TU6A 5JH3A 2FUDA 9PAPA 2BDLA 8PCHA 2PNSA 2NQDB 3U8EA 1U5IA 1MS6A 4XUIA 1SNKA 2FO5A 2E03A 4DMXA 2OZ2A 3MTNA 3KSEA 2YJ8A 3PNRA 1PPNA 2E01A 3TNXA 1THEA 3MORA 1A6RA 4QRGA 3O0UA 3M99A 1CJLA 1BY8A 2G7YA 2PADA 1ITOA 5JA7A 2JQGR 4G54A 3N3GA 5A24A 3D9WA 1O0EA 2VHSA 3P5UA 4QRVA 1KHPA 1KXRA 2P0RA 1CS8A 2PREA 3QT4A 4CDFB 1U9QX 4P6EA 4OELA 2VHFA 1QMYA 4YYUA 3MHSA 1NL6A 2XU1A 5CVMA 3KX1A 3P5VA 2AIMA 3DF0A 2YJ9A 3V6CA 1YVBA 1X9YA 3NHEA 2R9MA 4YYVA 3I3TA 5CVNB 4C5PA 2ATOA 4YYSA 3QJ3A 2FT2A 3V6EA 2IPPB 1K3BB 2H7JA 3OVXA 3ERVA 1QOLA 3BWKA 2F7DA 4NV8A 7PCKA 1YK7A 3AI8A 3F5VA 4BPVA 5CHVA 3KFQA 1STFE 4N8WA 2P86A 2G8JA 1F29A 1QDQA 1ME3A 4XR7A 1PIPA 1ZCMA 4YVAA 1YT7A 5PADA 4X6JA 1GLOA 1NB3A 1W5RA 3HWNA 1BQIA 2AUXA 3RVVA 5K16A 3H89A 5EGWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4I07 A;  1PXV A;  2NQI A;  2YJC A;  1AYV A;  4MZO A;  3WXF A;  1PBH A;  1CV8 A;  1KFX L;  4P6G A;  1MIR A;  5EF4 A;  4PP2 E;  2DCD A;  3N4C A;  4PP1 A;  4W5B A;  1MDW A;  3KWZ A;  4QH6 A;  1AU4 A;  4CDC B;  3F75 A;  1BP4 A;  2CIO A;  4BS6 A;  4AXL A;  1VJV A;  2R9N A;  1HUC B;  1TLO A;  2AUZ A;  3B79 A;  4YYR A;  3WXE A;  1Q6K A;  2DZZ A;  1F2C A;  3I06 A;  2BDZ A;  2DZY A;  3OF8 A;  2FRA A;  1VSN A;  3IV2 A;  1ZIV A;  1ME4 A;  2IBI A;  4FIP A;  1NB5 A;  4YYQ A;  4BS5 A;  1F2B A;  4N4Z A;  3KWB X;  2DJG B;  2FTD A;  2DCB A;  3BPM A;  3P5W A;  2DC7 A;  5CVO B;  1CVZ A;  1CPJ A;  4ZUX U;  3HHI A;  2E02 A;  4W5C A;  3PW3 A;  2GFO A;  2R6N A;  3IOQ A;  3D6S A;  4RY2 A;  3H7D A;  1ATK A;  2AS8 A;  2R9F A;  1EWP A;  2HXZ A;  1NLJ A;  2CB5 A;  1F2A A;  2PBH A;  2JQF R;  6PAD A;  3MHH A;  5F02 A;  2XU5 A;  2P7U A;  1S4V A;  3N3K A;  3K24 A;  4QBB A;  3RVW A;  1M6D A;  1SP4 B;  1KFU L;  3BPF A;  1ICF A;  3P5X A;  4I04 A;  1YK8 A;  3S3Q A;  3IEJ A;  3BC3 A;  3K8U A;  1EWM A;  3OVZ A;  1KHQ A;  3HD3 A;  3LFY A;  2NQG A;  3HHA A;  1GCB A;  3H8B A;  1BGO A;  3PBH A;  4AXM A;  1AYU A;  5CHT A;  1FH0 A;  2DCC A;  1CTE A;  2ARY A;  1AYW A;  1CB5 A;  1TL9 A;  2GHU A;  1CQD A;  2FQ9 A;  2WBF X;  1AEC A;  1AU2 A;  2DC8 A;  4Q8G A;  1PE6 A;  2XU4 A;  2AVW A;  3H8C A;  1EWO A;  3WXG A;  4YV8 A;  3OF9 A;  4FJC A;  4MSX A;  4PAD A;  4MZS A;  3H6S A;  4HWY A;  1Y08 A;  4N79 A;  4DMY A;  2OP3 A;  3RVX A;  1XKG A;  3IMA A;  1PCI A;  3KKU A;  3PDF A;  1AU3 A;  2R9C A;  2O6X A;  2HD5 A;  1CSB B;  1NPZ A;  1AIM A;  3IHP A;  4Q8H A;  2F1G A;  2YJB A;  1PPP A;  1NQC A;  1YAL A;  3ZUA A;  3CH3 X;  1IWD A;  3BCN A;  4YYW A;  1AU0 A;  3GCB A;  1MEM A;  2HH5 A;  1U9W A;  4K7C A;  1POP A;  1U9X A;  2B1M A;  2E00 A;  2AU1 A;  4X6H A;  4CDE B;  5FPW A;  4CZW A;  3OIS A;  1EF7 A;  2Y6E A;  3QSD A;  1GMY A;  3USV A;  1MEG A;  4WA6 A;  2YJ2 A;  1GEC E;  4W4U A;  1PPD A;  2DCA A;  2XU3 A;  5J94 A;  3E1Z B;  4I05 A;  3O1G A;  3C9E A;  4KLB A;  3CBJ A;  1Y4H A;  3KW9 A;  1QXP A;  1PAD A;  4CDD B;  3IUT A;  2NQA A;  2DJF B;  4X6I A;  4PI3 A;  2G6D A;  2DC9 A;  2HHN A;  1MHW A;  1EWL A;  2OUL A;  4QRX A;  1PPO A;  2G8E A;  3BOW A;  4FK5 A;  2Y5B A;  3K9M A;  2R9O A;  3CBK A;  1U9V A;  3S3R A;  4BQV A;  1DF0 A;  4BSQ A;  3LXS A;  2AYO A;  2FYE A;  2AYN A;  2C0Y A;  2DC6 A;  1JQP A;  1DEU A;  2B1N A;  3CH2 X;  2ACT A;  4OEM A;  2FRQ A;  1TU6 A;  5JH3 A;  2FUD A;  9PAP A;  2BDL A;  8PCH A;  2PNS A;  2NQD B;  3U8E A;  1U5I A;  1MS6 A;  4XUI A;  1SNK A;  2FO5 A;  2E03 A;  4DMX A;  2OZ2 A;  3MTN A;  3KSE A;  2YJ8 A;  3PNR A;  1PPN A;  2E01 A;  3TNX A;  1THE A;  3MOR A;  1A6R A;  4QRG A;  3O0U A;  3M99 A;  1CJL A;  1BY8 A;  2G7Y A;  2PAD A;  1ITO A;  5JA7 A;  2JQG R;  4G54 A;  3N3G A;  5A24 A;  1O0E A;  2VHS A;  3P5U A;  4QRV A;  1KHP A;  1KXR A;  2P0R A;  1CS8 A;  2PRE A;  3QT4 A;  4CDF B;  1U9Q X;  4P6E A;  4OEL A;  2VHF A;  1QMY A;  4YYU A;  3MHS A;  1NL6 A;  2XU1 A;  5CVM A;  3KX1 A;  3P5V A;  2AIM A;  3DF0 A;  2YJ9 A;  3V6C A;  1YVB A;  1X9Y A;  3NHE A;  2R9M A;  4YYV A;  3I3T A;  5CVN B;  2ATO A;  4YYS A;  3QJ3 A;  2FT2 A;  3V6E A;  2IPP B;  1K3B B;  2H7J A;  3OVX A;  3ERV A;  1QOL A;  3BWK A;  2F7D A;  7PCK A;  1YK7 A;  3AI8 A;  3F5V A;  4BPV A;  5CHV A;  3KFQ A;  1STF E;  4N8W A;  2P86 A;  2G8J A;  1F29 A;  1QDQ A;  1ME3 A;  4XR7 A;  1PIP A;  1ZCM A;  4YVA A;  1YT7 A;  5PAD A;  4X6J A;  1GLO A;  1NB3 A;  3HWN A;  1BQI A;  2AUX A;  3RVV A;  5K16 A;  3H89 A;  5EGW A; 
#chains in the Genus database with same CATH topology
 4I07 A;  4BOZ A;  1PXV A;  2NQI A;  4BOS A;  4RF1 A;  2YJC A;  1AYV A;  4MZO A;  3WXF A;  1PBH A;  1CV8 A;  1KFX L;  4P6G A;  2AGA A;  1MIR A;  3PHX A;  1UKF A;  5EF4 A;  4PP2 E;  3ZNH A;  2DCD A;  3N4C A;  4PP1 A;  4W5B A;  1MDW A;  3KWZ A;  4QH6 A;  1AU4 A;  4CDC B;  3F75 A;  1BP4 A;  2CIO A;  4M0W A;  4BS6 A;  4AXL A;  3MP2 A;  1VJV A;  2R9N A;  1HUC B;  1TLO A;  2AUZ A;  3B79 A;  4YYR A;  3E9S A;  3WXE A;  1Q6K A;  2DZZ A;  1F2C A;  3I06 A;  2BDZ A;  2DZY A;  3OF8 A;  3C0R A;  2FRA A;  1VSN A;  3IV2 A;  1ZIV A;  1ME4 A;  4P16 A;  2IBI A;  4FIP A;  4REZ A;  1NB5 A;  4YYQ A;  3PHW A;  4BS5 A;  1F2B A;  3O65 A;  4N4Z A;  3KWB X;  2DJG B;  2FTD A;  2DCB A;  3BPM A;  3P5W A;  2DC7 A;  5CVO B;  1CVZ A;  3W31 A;  1CPJ A;  4ZUX U;  3HHI A;  2E02 A;  4W5C A;  3PW3 A;  4D8B A;  2GFO A;  2R6N A;  3IOQ A;  2J7Q C;  5JZE A;  3D6S A;  4RY2 A;  3H7D A;  1ATK A;  2AS8 A;  2R9F A;  1EWP A;  2HXZ A;  1NLJ A;  2CB5 A;  1F2A A;  2PBH A;  2JQF R;  6PAD A;  3MHH A;  5F02 A;  4OVZ B;  2XU5 A;  2P7U A;  1S4V A;  3N3K A;  3K24 A;  4QBB A;  3RVW A;  1M6D A;  1SP4 B;  1KFU L;  3BPF A;  1ICF A;  3P5X A;  4I04 A;  1YK8 A;  2JRI A;  3S3Q A;  3IEJ A;  1YZB A;  5EZS A;  3BC3 A;  3K8U A;  1EWM A;  3OVZ A;  4PT5 A;  1KHQ A;  2BTW A;  3HD3 A;  4RNA A;  3LFY A;  2NQG A;  3HHA A;  1GCB A;  3H8B A;  1BGO A;  3PBH A;  4AXM A;  1AYU A;  5CHT A;  1FH0 A;  2DCC A;  4MM3 B;  1CTE A;  2ARY A;  1AYW A;  1CB5 A;  1TL9 A;  2GHU A;  1CQD A;  2FQ9 A;  2WBF X;  4D8E A;  1AEC A;  1AU2 A;  2DC8 A;  4Q8G A;  1PE6 A;  2XU4 A;  5KO3 A;  2AVW A;  3H8C A;  2UZJ A;  1EWO A;  3WXG A;  4YV8 A;  3OF9 A;  4FJC A;  4MSX A;  4PAD A;  4MZS A;  3H6S A;  4HWY A;  3PRM A;  1Y08 A;  4N79 A;  4DMY A;  2OP3 A;  3IFU A;  1DKI A;  3RVX A;  1XKG A;  3IMA A;  1PCI A;  3KKU A;  1PVJ A;  3PDF A;  1AU3 A;  2R9C A;  5EZQ A;  2JTC A;  2O6X A;  2HD5 A;  1CSB B;  1NPZ A;  1AIM A;  3IHP A;  4Q8H A;  2J7Q A;  3BB7 A;  2F1G A;  2YJB A;  1PPP A;  2BU3 A;  1NQC A;  1YAL A;  3ZUA A;  3CH3 X;  1IWD A;  3BCN A;  4YYW A;  1AU0 A;  3GCB A;  3B21 A;  1MEM A;  2HH5 A;  1U9W A;  4K7C A;  1POP A;  1U9X A;  2B1M A;  2E00 A;  2AU1 A;  4X6H A;  4GUA A;  4CDE B;  5FPW A;  4BOP A;  4CZW A;  3OIS A;  1EF7 A;  2Y6E A;  3QSD A;  1GMY A;  3USV A;  1MEG A;  4WA6 A;  2YJ2 A;  3PHU A;  1GEC E;  4W4U A;  1PPD A;  2DCA A;  2XU3 A;  5J94 A;  3E1Z B;  4I05 A;  3W30 A;  3O1G A;  3C9E A;  4KLB A;  3CBJ A;  1Y4H A;  3KW9 A;  3BY4 A;  1QXP A;  2DOS A;  1PAD A;  4CDD B;  3IUT A;  4XZX A;  2NQA A;  2DJF B;  4X6I A;  4PI3 A;  2G6D A;  2DC9 A;  2HHN A;  1MHW A;  1EWL A;  2OUL A;  4QRX A;  1PPO A;  2G8E A;  3BOW A;  4FK5 A;  2Y5B A;  4IP3 A;  3TRK A;  3K9M A;  2R9O A;  3CBK A;  1U9V A;  4ZTB A;  2FE8 A;  5E6J A;  3S3R A;  4BQV A;  1DF0 A;  4BSQ A;  3LXS A;  4MI7 A;  2AYO A;  2FYE A;  2AYN A;  2C0Y A;  2DC6 A;  1JQP A;  1DEU A;  2B1N A;  3CH2 X;  2ACT A;  3MJ5 A;  4OEM A;  3PSE A;  2FRQ A;  1TU6 A;  5JH3 A;  2FUD A;  9PAP A;  2BDL A;  8PCH A;  2PNS A;  2NQD B;  3U8E A;  1U5I A;  1MS6 A;  4XUI A;  1SNK A;  2FO5 A;  2E03 A;  4DMX A;  2OZ2 A;  3MTN A;  3KSE A;  2YJ8 A;  3PNR A;  1PPN A;  2E01 A;  3TNX A;  4D8I A;  1THE A;  3MOR A;  1A6R A;  4QRG A;  4OVZ A;  3O0U A;  3RNV A;  3M99 A;  3OQC A;  1CJL A;  1BY8 A;  2G7Y A;  2PAD A;  3TMP A;  1ITO A;  5JA7 A;  2JQG R;  4G54 A;  3N3G A;  5A24 A;  1O0E A;  2VHS A;  3P5U A;  4QRV A;  1KHP A;  1KXR A;  2P0R A;  3PRP A;  4WUR A;  1CS8 A;  2BTW B;  2PRE A;  3QT4 A;  4CDF B;  1U9Q X;  4P6E A;  4OEL A;  2VHF A;  1QMY A;  4YYU A;  3MHS A;  1NL6 A;  2XU1 A;  5CVM A;  2HWK A;  3BBA A;  4HXD B;  3KX1 A;  3P5V A;  2AIM A;  4RKX A;  3DF0 A;  4BOU A;  2YJ9 A;  4IUM A;  3V6C A;  1YVB A;  1X9Y A;  3NHE A;  2R9M A;  4YYV A;  3I3T A;  5CVN B;  2ATO A;  4YYS A;  3QJ3 A;  2FT2 A;  3V6E A;  2IPP B;  1K3B B;  2H7J A;  3OVX A;  3ERV A;  1QOL A;  3BWK A;  2F7D A;  7PCK A;  1YK7 A;  3AI8 A;  3F5V A;  4BPV A;  2Z84 A;  5CHV A;  3PT2 A;  3KFQ A;  1STF E;  4N8W A;  2P86 A;  4R3D A;  2G8J A;  1F29 A;  1QDQ A;  1ME3 A;  4XR7 A;  1PIP A;  1ZCM A;  4OW0 A;  4YVA A;  1YT7 A;  5PAD A;  4X6J A;  1GLO A;  1NB3 A;  4RF0 A;  3MTV A;  3HWN A;  1BQI A;  2AUX A;  3RVV A;  5K16 A;  3H89 A;  4A5U A;  4BOQ A;  5EGW A; 
#chains in the Genus database with same CATH homology
 4I07 A;  1PXV A;  2NQI A;  2YJC A;  4NV7 A;  1AYV A;  4MZO A;  3WXF A;  1E2T A;  1PBH A;  1CV8 A;  1KFX L;  4P6G A;  1MIR A;  5EF4 A;  4PP2 E;  2DCD A;  3N4C A;  4PP1 A;  4W5B A;  1MDW A;  3KWZ A;  4QH6 A;  1AU4 A;  4CDC B;  3F75 A;  1BP4 A;  2CIO A;  4BS6 A;  4AXL A;  1VJV A;  1W6F A;  2R9N A;  1HUC B;  1TLO A;  2AUZ A;  3B79 A;  4YYR A;  3WXE A;  1Q6K A;  2DZZ A;  1F2C A;  3I06 A;  2BDZ A;  2DZY A;  3OF8 A;  2FRA A;  1VSN A;  3IV2 A;  1ZIV A;  1ME4 A;  2IBI A;  4FIP A;  1NB5 A;  4YYQ A;  4BS5 A;  1F2B A;  4N4Z A;  3KWB X;  2DJG B;  2FTD A;  2DCB A;  4BGF A;  3BPM A;  3P5W A;  2DC7 A;  5CVO B;  1CVZ A;  1CPJ A;  4ZUX U;  2BSZ A;  3HHI A;  2E02 A;  2VFC A;  4W5C A;  3PW3 A;  2GFO A;  2R6N A;  3IOQ A;  3D6S A;  4RY2 A;  3H7D A;  1ATK A;  2AS8 A;  2R9F A;  1EWP A;  2HXZ A;  1NLJ A;  2CB5 A;  1F2A A;  2PBH A;  2JQF R;  6PAD A;  3MHH A;  5F02 A;  2XU5 A;  2P7U A;  1S4V A;  3N3K A;  3K24 A;  4QBB A;  3RVW A;  1M6D A;  1SP4 B;  1KFU L;  3BPF A;  1ICF A;  3P5X A;  4I04 A;  1YK8 A;  3S3Q A;  3IEJ A;  3BC3 A;  3K8U A;  1EWM A;  3OVZ A;  1KHQ A;  4B55 A;  3HD3 A;  2VFB A;  3LFY A;  2NQG A;  3HHA A;  1GCB A;  3H8B A;  1BGO A;  3PBH A;  4AXM A;  1AYU A;  5CHT A;  1FH0 A;  2DCC A;  1CTE A;  2ARY A;  1AYW A;  1CB5 A;  1TL9 A;  2GHU A;  1CQD A;  2FQ9 A;  2WBF X;  4GUZ A;  1AEC A;  1AU2 A;  2DC8 A;  4Q8G A;  1PE6 A;  2XU4 A;  2AVW A;  3H8C A;  1GX3 A;  1EWO A;  3WXG A;  4YV8 A;  3OF9 A;  4FJC A;  4MSX A;  4PAD A;  4MZS A;  3H6S A;  4HWY A;  1Y08 A;  4N79 A;  4DMY A;  2OP3 A;  3RVX A;  1XKG A;  3IMA A;  1PCI A;  3KKU A;  3PDF A;  1AU3 A;  2R9C A;  2O6X A;  2HD5 A;  1CSB B;  1NPZ A;  3LTW A;  1AIM A;  3IHP A;  4Q8H A;  2F1G A;  2YJB A;  1PPP A;  1NQC A;  1YAL A;  3ZUA A;  3CH3 X;  1IWD A;  3BCN A;  4YYW A;  1AU0 A;  3GCB A;  1MEM A;  2HH5 A;  1U9W A;  4K7C A;  1POP A;  1U9X A;  2B1M A;  2E00 A;  2AU1 A;  4X6H A;  4CDE B;  5FPW A;  4CZW A;  3OIS A;  1EF7 A;  2Y6E A;  3QSD A;  1GMY A;  3USV A;  1W4T A;  1MEG A;  4WA6 A;  2YJ2 A;  1GEC E;  4W4U A;  1PPD A;  2DCA A;  2XU3 A;  5J94 A;  3E1Z B;  4I05 A;  3O1G A;  3C9E A;  4KLB A;  3CBJ A;  1Y4H A;  3KW9 A;  1QXP A;  1PAD A;  4CDD B;  3IUT A;  2NQA A;  2DJF B;  4X6I A;  4PI3 A;  2G6D A;  2DC9 A;  2HHN A;  1MHW A;  1EWL A;  2OUL A;  4QRX A;  1PPO A;  2G8E A;  3BOW A;  4FK5 A;  2Y5B A;  3K9M A;  2R9O A;  3CBK A;  1U9V A;  3S3R A;  4BQV A;  1DF0 A;  4BSQ A;  3LXS A;  2AYO A;  2FYE A;  2AYN A;  2C0Y A;  2DC6 A;  1JQP A;  1DEU A;  2B1N A;  3CH2 X;  2ACT A;  4OEM A;  2FRQ A;  1TU6 A;  5JH3 A;  2FUD A;  9PAP A;  2BDL A;  8PCH A;  2PNS A;  2NQD B;  3U8E A;  1U5I A;  1MS6 A;  4XUI A;  1SNK A;  2FO5 A;  2E03 A;  4DMX A;  2OZ2 A;  3MTN A;  3KSE A;  2YJ8 A;  3PNR A;  1PPN A;  2E01 A;  3TNX A;  1THE A;  3MOR A;  1A6R A;  4QRG A;  3O0U A;  3M99 A;  1CJL A;  1BY8 A;  2G7Y A;  2PAD A;  1ITO A;  5JA7 A;  2JQG R;  4G54 A;  3N3G A;  5A24 A;  3D9W A;  1O0E A;  2VHS A;  3P5U A;  4QRV A;  1KHP A;  1KXR A;  2P0R A;  1CS8 A;  2PRE A;  3QT4 A;  4CDF B;  1U9Q X;  4P6E A;  4OEL A;  2VHF A;  1QMY A;  4YYU A;  3MHS A;  1NL6 A;  2XU1 A;  5CVM A;  3KX1 A;  3P5V A;  2AIM A;  3DF0 A;  2YJ9 A;  3V6C A;  1YVB A;  1X9Y A;  3NHE A;  2R9M A;  4YYV A;  3I3T A;  5CVN B;  4C5P A;  2ATO A;  4YYS A;  3QJ3 A;  2FT2 A;  3V6E A;  2IPP B;  1K3B B;  2H7J A;  3OVX A;  3ERV A;  1QOL A;  3BWK A;  2F7D A;  4NV8 A;  7PCK A;  1YK7 A;  3AI8 A;  3F5V A;  4BPV A;  5CHV A;  3KFQ A;  1STF E;  4N8W A;  2P86 A;  2G8J A;  1F29 A;  1QDQ A;  1ME3 A;  4XR7 A;  1PIP A;  1ZCM A;  4YVA A;  1YT7 A;  5PAD A;  4X6J A;  1GLO A;  1NB3 A;  1W5R A;  3HWN A;  1BQI A;  2AUX A;  3RVV A;  5K16 A;  3H89 A;  5EGW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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