1CS8A

Crystal structure of procathepsin l
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
316
structure length
315
Chain Sequence
SLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDAGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment.
pubmed rcsb
source organism Homo sapiens
molecule tags Hydrolase
molecule keywords HUMAN PROCATHEPSIN L
total genus 63
structure length 315
sequence length 316
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 1999-08-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
A PF08246 Inhibitor_I29 Cathepsin propeptide inhibitor domain (I29)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1cs8A00
5CHVA 1MIRA 4XR7A 7PCKA 9PAPA 2HH5A 3K24A 4W4UA 3RVVA 1HUCB 1PPOA 3RVWA 4CDCB 1YK8A 2DJGB 3CH2X 3B79A 3S3RA 1A6RA 1POPA 1PXVA 1QDQA 5EGWA 2DCAA 1QXPA 4QRXA 4YYWA 2P7UA 3N4CA 1U9VA 3KWZA 1NPZA 4KLBA 3H6SA 2IPPB 1KFUL 3LFYA 3P5WA 4QRGA 3K8UA 4P6EA 1QMYA 3PBHA 3F5VA 3KWBX 2YJCA 1EWLA 4X6HA 3HWNA 2FYEA 3C9EA 1CJLA 1U9QX 1ATKA 3KX1A 3QT4A 1DEUA 3H89A 1CS8A 4CDFB 2FRQA 3PNRA 4QRVA 4Q8GA 1F2CA 1U9XA 3D6SA 4OELA 3IHPA 3P5VA 1U5IA 5CVNB 2AYNA 4QBBA 1AU3A 3CH3X 2YJ8A 3RVXA 5K16A 2NQIA 1ZIVA 3M99A 4X6IA 1GCBA 5EF4A 1FH0A 2NQGA 4YYVA 3BPFA 3MHHA 3IOQA 3TNXA 2VHFA 1MS6A 4W5CA 2DC7A 1NB5A 3WXGA 4BS6A 2F1GA 3ERVA 3CBJA 3O1GA 2DZZA 1TU6A 2YJ2A 1ITOA 1EWOA 4CDEB 1CTEA 2XU3A 3I3TA 4AXMA 4AXLA 4BSQA 3KFQA 1PE6A 2AU1A 3OF9A 1AU0A 1AIMA 4YYUA 2FTDA 4N4ZA 3MHSA 2R9FA 3N3KA 2FQ9A 2PNSA 2BDZA 2BDLA 1ME3A 2R9MA 1CSBB 1SNKA 1Y4HA 1PCIA 3QJ3A 1Q6KA 2E01A 4MZSA 3IMAA 3IV2A 2R9OA 3WXFA 3USVA 2DCCA 5JH3A 3GCBA 4FJCA 2R9CA 1CQDA 2AVWA 3MORA 3CBKA 5JA7A 3AI8A 3H8BA 1THEA 2NQAA 2ARYA 3P5UA 4I05A 1GECE 3I06A 2HD5A 1GLOA 4N79A 1NQCA 1YVBA 1KHPA 3BOWA 2E03A 1ME4A 1STFE 5A24A 1YT7A 3MTNA 1SP4B 2WBFX 2DC6A 1DF0A 1PBHA 1F2BA 5FPWA 2XU4A 1YK7A 2AYOA 4ZUXU 1F29A 3IEJA 4FK5A 3OF8A 4DMYA 4HWYA 1AU2A 1NLJA 1MDWA 1BY8A 1S4VA 3QSDA 1PPNA 1BP4A 4G54A 6PADA 1AYVA 2JQGR 2HHNA 2R6NA 4CZWA 5F02A 4WA6A 3ZUAA 3OVXA 2G8JA 2FUDA 2C0YA 1YALA 2XU5A 1BQIA 4YVAA 3N3GA 2NQDB 3E1ZB 1EF7A 1AECA 3KKUA 5J94A 3BC3A 2IBIA 4W5BA 2FRAA 1JQPA 1VJVA 3KW9A 3BPMA 2CIOA 2R9NA 2AIMA 2P0RA 2AS8A 4N8WA 3PW3A 3V6CA 2DJFB 1KXRA 1NL6A 1CPJA 4YYRA 3NHEA 1ICFA 4MSXA 3S3QA 1ZCMA 1AYUA 2YJ9A 1CB5A 2E02A 2DC9A 1PIPA 2FO5A 3U8EA 2GHUA 3DF0A 4OEMA 1EWPA 1MEMA 1NB3A 2YJBA 3PDFA 4FIPA 4XUIA 4BPVA 3H8CA 1O0EA 2Y6EA 5CVOB 1CV8A 3WXEA 3O0UA 2P86A 3BCNA 4DMXA 2G7YA 5PADA 2PBHA 3IUTA 1X9YA 1PADA 3KSEA 1GMYA 1KHQA 4PP2E 1MHWA 2OP3A 3OISA 3HHIA 2DCDA 1AU4A 1VSNA 2G8EA 1KFXL 2E00A 2PADA 2ACTA 2GFOA 2O6XA 2DCBA 4BS5A 3HD3A 4RY2A 2F7DA 3BWKA 2B1MA 2G6DA 1IWDA 2VHSA 5CVMA 3K9MA 3V6EA 1EWMA 2H7JA 2FT2A 4YYQA 1F2AA 4PADA 3H7DA 1XKGA 1TLOA 5CHTA 1M6DA 3LXSA 3OVZA 2B1NA 1U9WA 4CDDB 4PP1A 4YYSA 4I07A 4BQVA 1BGOA 1Y08A 4MZOA 4I04A 4Q8HA 4X6JA 2DZYA 1AYWA 4P6GA 1MEGA 4PI3A 2OZ2A 2AUZA 4YV8A 2PREA 1TL9A 2ATOA 2OULA 4K7CA 8PCHA 3F75A 2CB5A 4QH6A 3HHAA 2AUXA 2Y5BA 1CVZA 2XU1A 3P5XA 1PPDA 2DC8A 1K3BB 2JQFR 2HXZA 1QOLA 1PPPA
chains in the Genus database with same CATH superfamily
5CHVA 1MIRA 4XR7A 7PCKA 9PAPA 2HH5A 3K24A 4W4UA 3RVVA 1HUCB 1PPOA 4XZXA 3RVWA 4CDCB 1YK8A 2DJGB 3CH2X 3B79A 3S3RA 1A6RA 1POPA 1PXVA 1QDQA 5EGWA 2DCAA 1QXPA 4QRXA 4YYWA 2P7UA 3N4CA 2DOSA 1U9VA 3KWZA 1NPZA 4KLBA 3H6SA 2J7QA 5EZQA 2IPPB 1KFUL 4REZA 3LFYA 3P5WA 4QRGA 3W30A 4RKXA 3K8UA 3BB7A 4P6EA 1QMYA 3PBHA 3F5VA 3O65A 3KWBX 4BOQA 2YJCA 4ZTBA 1EWLA 2BTWB 4X6HA 3HWNA 2FYEA 3C9EA 1CJLA 1U9QX 1ATKA 3KX1A 3QT4A 1DEUA 3H89A 1CS8A 4CDFB 2FRQA 3PNRA 1PVJA 4QRVA 4Q8GA 1F2CA 1U9XA 3E9SA 3D6SA 4OELA 3IHPA 3P5VA 1U5IA 5CVNB 2AYNA 3MTVA 4QBBA 3IFUA 1AU3A 3CH3X 2YJ8A 3RVXA 5K16A 2NQIA 1ZIVA 3M99A 4RF0A 4X6IA 1GCBA 1FH0A 5EF4A 2NQGA 4YYVA 3BPFA 3MHHA 3IOQA 3TNXA 3RNVA 2VHFA 1MS6A 4W5CA 3ZNHA 2DC7A 1NB5A 3WXGA 4BS6A 2F1GA 3ERVA 3CBJA 3O1GA 2DZZA 3TRKA 1TU6A 2YJ2A 1ITOA 1EWOA 4CDEB 1CTEA 2XU3A 3I3TA 4AXMA 4AXLA 4A5UA 4BSQA 3KFQA 1PE6A 2AU1A 5JZEA 3OF9A 1AU0A 3OQCA 1AIMA 4YYUA 2FTDA 4BOUA 4N4ZA 3MHSA 2R9FA 4RNAA 3N3KA 2FQ9A 2PNSA 1DKIA 2BDZA 2BDLA 1ME3A 2R9MA 1CSBB 1SNKA 1Y4HA 1PCIA 3MP2A 3QJ3A 1Q6KA 2E01A 4MZSA 3IMAA 3IV2A 2R9OA 3WXFA 3USVA 2DCCA 5JH3A 3GCBA 4OW0A 4FJCA 2R9CA 1CQDA 2AVWA 4MM3B 3MORA 3CBKA 4D8EA 5JA7A 3AI8A 3H8BA 1THEA 2NQAA 2ARYA 3PT2A 3P5UA 4I05A 1GECE 3I06A 2HD5A 1GLOA 4N79A 1NQCA 1YVBA 1KHPA 3BOWA 3W31A 2E03A 1ME4A 1STFE 4OVZA 5A24A 1YT7A 2JRIA 3MTNA 1SP4B 2WBFX 2DC6A 1DF0A 1PBHA 1F2BA 5FPWA 2XU4A 1YK7A 2AYOA 4ZUXU 1F29A 3IEJA 4IP3A 4FK5A 3OF8A 4DMYA 4HWYA 1AU2A 3TMPA 1NLJA 1MDWA 1BY8A 1S4VA 3QSDA 1PPNA 1BP4A 4G54A 6PADA 1AYVA 2JQGR 2HHNA 2R6NA 4CZWA 5F02A 3BBAA 1YZBA 4WA6A 3ZUAA 3OVXA 2G8JA 2FUDA 5E6JA 2C0YA 1YALA 2XU5A 1BQIA 4YVAA 3N3GA 4D8IA 3B21A 2NQDB 3E1ZB 1EF7A 1AECA 2FE8A 3KKUA 3MJ5A 5J94A 3BC3A 2IBIA 4W5BA 2FRAA 1JQPA 1VJVA 3KW9A 3BPMA 2CIOA 4M0WA 2R9NA 2AIMA 2UZJA 2P0RA 2AS8A 4D8BA 4N8WA 3PW3A 3V6CA 2DJFB 1KXRA 1NL6A 1CPJA 3C0RA 4YYRA 3BY4A 1UKFA 3NHEA 1ICFA 4MSXA 3S3QA 1ZCMA 4PT5A 1AYUA 2YJ9A 1CB5A 2E02A 2DC9A 1PIPA 2FO5A 3U8EA 2GHUA 3DF0A 4OEMA 1EWPA 1MEMA 1NB3A 2YJBA 4GUAA 3PDFA 4IUMA 4FIPA 4XUIA 4BPVA 3H8CA 1O0EA 2Y6EA 5CVOB 1CV8A 4BOPA 3WXEA 4BOSA 3O0UA 2P86A 3BCNA 4DMXA 2G7YA 3PHUA 5PADA 2PBHA 3IUTA 4WURA 1X9YA 1PADA 3KSEA 1GMYA 1KHQA 4PP2E 1MHWA 2OP3A 3OISA 3HHIA 2DCDA 1AU4A 3PSEA 1VSNA 2G8EA 2BTWA 1KFXL 2E00A 2J7QC 2PADA 2ACTA 4R3DA 2GFOA 2O6XA 2DCBA 4BS5A 4BOZA 3HD3A 4RY2A 5KO3A 2F7DA 3BWKA 2B1MA 3PRMA 2G6DA 1IWDA 2VHSA 5CVMA 3K9MA 3V6EA 1EWMA 2H7JA 5EZSA 2FT2A 4YYQA 1F2AA 4PADA 3H7DA 1XKGA 1TLOA 5CHTA 1M6DA 3LXSA 3OVZA 2HWKA 2B1NA 1U9WA 4OVZB 4CDDB 4PP1A 4RF1A 4YYSA 4I07A 4BQVA 1BGOA 4P16A 2JTCA 1Y08A 3PRPA 4MZOA 4MI7A 2BU3A 4I04A 3PHXA 4Q8HA 4X6JA 2DZYA 1AYWA 4P6GA 1MEGA 4PI3A 2OZ2A 2AUZA 2AGAA 4YV8A 4HXDB 2PREA 1TL9A 2ATOA 2OULA 2Z84A 4K7CA 8PCHA 3F75A 2CB5A 4QH6A 3HHAA 3PHWA 2AUXA 2Y5BA 1CVZA 2XU1A 3P5XA 1PPDA 2DC8A 1K3BB 2JQFR 2HXZA 1QOLA 1PPPA
chains in the Genus database with same CATH topology
5CHVA 1MIRA 4XR7A 7PCKA 9PAPA 2HH5A 3K24A 4W4UA 3RVVA 1HUCB 1PPOA 3RVWA 4CDCB 1YK8A 2DJGB 3CH2X 3B79A 3S3RA 1A6RA 1POPA 1PXVA 1QDQA 5EGWA 2DCAA 1QXPA 4QRXA 4YYWA 2P7UA 3N4CA 1U9VA 3KWZA 1NPZA 4KLBA 3H6SA 2IPPB 1KFUL 3LFYA 3P5WA 4QRGA 4BGFA 3K8UA 4P6EA 1QMYA 3PBHA 3F5VA 3KWBX 2YJCA 4GUZA 4NV8A 1EWLA 4X6HA 3HWNA 2FYEA 3C9EA 1CJLA 1U9QX 1ATKA 2BSZA 3KX1A 3D9WA 3QT4A 1DEUA 3H89A 1CS8A 4CDFB 2FRQA 3PNRA 4QRVA 4Q8GA 1F2CA 1U9XA 3D6SA 4OELA 3IHPA 3P5VA 1U5IA 5CVNB 2AYNA 4QBBA 1AU3A 3CH3X 2YJ8A 3RVXA 5K16A 2VFCA 2NQIA 1ZIVA 3M99A 4X6IA 1GCBA 5EF4A 1FH0A 2NQGA 4YYVA 3BPFA 3MHHA 3IOQA 3TNXA 2VHFA 1MS6A 4W5CA 2DC7A 1NB5A 3WXGA 4BS6A 2F1GA 3ERVA 1E2TA 3CBJA 3O1GA 2DZZA 1TU6A 2YJ2A 1ITOA 1EWOA 4CDEB 1CTEA 2XU3A 3I3TA 4AXMA 4AXLA 4BSQA 3KFQA 4NV7A 1PE6A 2AU1A 3OF9A 1AU0A 1AIMA 4YYUA 4B55A 2FTDA 4N4ZA 3MHSA 2R9FA 3N3KA 2FQ9A 2PNSA 2BDZA 2BDLA 1ME3A 2R9MA 1CSBB 1SNKA 1Y4HA 1PCIA 3QJ3A 1Q6KA 2E01A 4MZSA 3IMAA 3IV2A 2R9OA 3WXFA 3USVA 2DCCA 5JH3A 3GCBA 4FJCA 2R9CA 1CQDA 2AVWA 3MORA 3CBKA 5JA7A 3AI8A 3H8BA 1THEA 2NQAA 2ARYA 3P5UA 4I05A 1GECE 3I06A 2HD5A 1GLOA 4N79A 1NQCA 1YVBA 1KHPA 3BOWA 2E03A 3LTWA 1ME4A 1STFE 5A24A 1YT7A 3MTNA 1SP4B 2WBFX 2DC6A 1DF0A 1PBHA 1F2BA 5FPWA 2XU4A 1YK7A 2AYOA 4ZUXU 1F29A 3IEJA 4FK5A 3OF8A 4DMYA 4HWYA 1AU2A 1NLJA 1MDWA 1BY8A 1S4VA 3QSDA 1PPNA 1BP4A 4G54A 6PADA 1AYVA 2JQGR 2HHNA 2R6NA 4CZWA 5F02A 4WA6A 3ZUAA 3OVXA 2G8JA 2FUDA 2C0YA 1YALA 2XU5A 1BQIA 4YVAA 3N3GA 2NQDB 3E1ZB 1EF7A 1AECA 3KKUA 5J94A 3BC3A 2IBIA 4W5BA 2FRAA 1JQPA 1VJVA 3KW9A 3BPMA 2CIOA 2R9NA 2AIMA 2P0RA 2AS8A 4N8WA 3PW3A 3V6CA 2DJFB 1KXRA 1NL6A 1CPJA 4YYRA 3NHEA 1ICFA 4MSXA 3S3QA 1ZCMA 1AYUA 2YJ9A 1CB5A 2E02A 2DC9A 1PIPA 2FO5A 3U8EA 2GHUA 3DF0A 4OEMA 1EWPA 1MEMA 1NB3A 2YJBA 3PDFA 4FIPA 4XUIA 4BPVA 3H8CA 1O0EA 2Y6EA 5CVOB 1CV8A 3WXEA 1W6FA 3O0UA 2P86A 3BCNA 4DMXA 2VFBA 2G7YA 5PADA 2PBHA 3IUTA 1X9YA 1PADA 3KSEA 1GMYA 1KHQA 4PP2E 1MHWA 2OP3A 3OISA 3HHIA 2DCDA 1AU4A 1VSNA 2G8EA 1KFXL 2E00A 2PADA 2ACTA 2GFOA 2O6XA 1W4TA 2DCBA 4BS5A 3HD3A 4RY2A 2F7DA 3BWKA 2B1MA 2G6DA 1IWDA 2VHSA 5CVMA 3K9MA 3V6EA 1EWMA 2H7JA 2FT2A 4YYQA 1F2AA 4PADA 3H7DA 1XKGA 1TLOA 5CHTA 1M6DA 3LXSA 3OVZA 2B1NA 1U9WA 4CDDB 4PP1A 4YYSA 4I07A 4BQVA 1BGOA 1Y08A 4MZOA 1W5RA 4I04A 4Q8HA 4X6JA 2DZYA 1AYWA 4P6GA 1MEGA 4PI3A 2OZ2A 2AUZA 4YV8A 4C5PA 2PREA 1TL9A 2ATOA 2OULA 4K7CA 8PCHA 3F75A 2CB5A 4QH6A 1GX3A 3HHAA 2AUXA 2Y5BA 1CVZA 2XU1A 3P5XA 1PPDA 2DC8A 1K3BB 2JQFR 2HXZA 1QOLA 1PPPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CHV A;  1MIR A;  4XR7 A;  7PCK A;  9PAP A;  2HH5 A;  3K24 A;  4W4U A;  3RVV A;  1HUC B;  1PPO A;  3RVW A;  4CDC B;  1YK8 A;  2DJG B;  3CH2 X;  3B79 A;  3S3R A;  1A6R A;  1POP A;  1PXV A;  1QDQ A;  5EGW A;  2DCA A;  1QXP A;  4QRX A;  4YYW A;  2P7U A;  3N4C A;  1U9V A;  3KWZ A;  1NPZ A;  4KLB A;  3H6S A;  2IPP B;  1KFU L;  3LFY A;  3P5W A;  4QRG A;  3K8U A;  4P6E A;  1QMY A;  3PBH A;  3F5V A;  3KWB X;  2YJC A;  1EWL A;  4X6H A;  3HWN A;  2FYE A;  3C9E A;  1CJL A;  1U9Q X;  1ATK A;  3KX1 A;  3QT4 A;  1DEU A;  3H89 A;  1CS8 A;  4CDF B;  2FRQ A;  3PNR A;  4QRV A;  4Q8G A;  1F2C A;  1U9X A;  3D6S A;  4OEL A;  3IHP A;  3P5V A;  1U5I A;  5CVN B;  2AYN A;  4QBB A;  1AU3 A;  3CH3 X;  2YJ8 A;  3RVX A;  5K16 A;  2NQI A;  1ZIV A;  3M99 A;  4X6I A;  1GCB A;  5EF4 A;  1FH0 A;  2NQG A;  4YYV A;  3BPF A;  3MHH A;  3IOQ A;  3TNX A;  2VHF A;  1MS6 A;  4W5C A;  2DC7 A;  1NB5 A;  3WXG A;  4BS6 A;  2F1G A;  3ERV A;  3CBJ A;  3O1G A;  2DZZ A;  1TU6 A;  2YJ2 A;  1ITO A;  1EWO A;  4CDE B;  1CTE A;  2XU3 A;  3I3T A;  4AXM A;  4AXL A;  4BSQ A;  3KFQ A;  1PE6 A;  2AU1 A;  3OF9 A;  1AU0 A;  1AIM A;  4YYU A;  2FTD A;  4N4Z A;  3MHS A;  2R9F A;  3N3K A;  2FQ9 A;  2PNS A;  2BDZ A;  2BDL A;  1ME3 A;  2R9M A;  1CSB B;  1SNK A;  1Y4H A;  1PCI A;  3QJ3 A;  1Q6K A;  2E01 A;  4MZS A;  3IMA A;  3IV2 A;  2R9O A;  3WXF A;  3USV A;  2DCC A;  5JH3 A;  3GCB A;  4FJC A;  2R9C A;  1CQD A;  2AVW A;  3MOR A;  3CBK A;  5JA7 A;  3AI8 A;  3H8B A;  1THE A;  2NQA A;  2ARY A;  3P5U A;  4I05 A;  1GEC E;  3I06 A;  2HD5 A;  1GLO A;  4N79 A;  1NQC A;  1YVB A;  1KHP A;  3BOW A;  2E03 A;  1ME4 A;  1STF E;  5A24 A;  1YT7 A;  3MTN A;  1SP4 B;  2WBF X;  2DC6 A;  1DF0 A;  1PBH A;  1F2B A;  5FPW A;  2XU4 A;  1YK7 A;  2AYO A;  4ZUX U;  1F29 A;  3IEJ A;  4FK5 A;  3OF8 A;  4DMY A;  4HWY A;  1AU2 A;  1NLJ A;  1MDW A;  1BY8 A;  1S4V A;  3QSD A;  1PPN A;  1BP4 A;  4G54 A;  6PAD A;  1AYV A;  2JQG R;  2HHN A;  2R6N A;  4CZW A;  5F02 A;  4WA6 A;  3ZUA A;  3OVX A;  2G8J A;  2FUD A;  2C0Y A;  1YAL A;  2XU5 A;  1BQI A;  4YVA A;  3N3G A;  2NQD B;  3E1Z B;  1EF7 A;  1AEC A;  3KKU A;  5J94 A;  3BC3 A;  2IBI A;  4W5B A;  2FRA A;  1JQP A;  1VJV A;  3KW9 A;  3BPM A;  2CIO A;  2R9N A;  2AIM A;  2P0R A;  2AS8 A;  4N8W A;  3PW3 A;  3V6C A;  2DJF B;  1KXR A;  1NL6 A;  1CPJ A;  4YYR A;  3NHE A;  1ICF A;  4MSX A;  3S3Q A;  1ZCM A;  1AYU A;  2YJ9 A;  1CB5 A;  2E02 A;  2DC9 A;  1PIP A;  2FO5 A;  3U8E A;  2GHU A;  3DF0 A;  4OEM A;  1EWP A;  1MEM A;  1NB3 A;  2YJB A;  3PDF A;  4FIP A;  4XUI A;  4BPV A;  3H8C A;  1O0E A;  2Y6E A;  5CVO B;  1CV8 A;  3WXE A;  3O0U A;  2P86 A;  3BCN A;  4DMX A;  2G7Y A;  5PAD A;  2PBH A;  3IUT A;  1X9Y A;  1PAD A;  3KSE A;  1GMY A;  1KHQ A;  4PP2 E;  1MHW A;  2OP3 A;  3OIS A;  3HHI A;  2DCD A;  1AU4 A;  1VSN A;  2G8E A;  1KFX L;  2E00 A;  2PAD A;  2ACT A;  2GFO A;  2O6X A;  2DCB A;  4BS5 A;  3HD3 A;  4RY2 A;  2F7D A;  3BWK A;  2B1M A;  2G6D A;  1IWD A;  2VHS A;  5CVM A;  3K9M A;  3V6E A;  1EWM A;  2H7J A;  2FT2 A;  4YYQ A;  1F2A A;  4PAD A;  3H7D A;  1XKG A;  1TLO A;  5CHT A;  1M6D A;  3LXS A;  3OVZ A;  2B1N A;  1U9W A;  4CDD B;  4PP1 A;  4YYS A;  4I07 A;  4BQV A;  1BGO A;  1Y08 A;  4MZO A;  4I04 A;  4Q8H A;  4X6J A;  2DZY A;  1AYW A;  4P6G A;  1MEG A;  4PI3 A;  2OZ2 A;  2AUZ A;  4YV8 A;  2PRE A;  1TL9 A;  2ATO A;  2OUL A;  4K7C A;  8PCH A;  3F75 A;  2CB5 A;  4QH6 A;  3HHA A;  2AUX A;  2Y5B A;  1CVZ A;  2XU1 A;  3P5X A;  1PPD A;  2DC8 A;  1K3B B;  2JQF R;  2HXZ A;  1QOL A;  1PPP A; 
#chains in the Genus database with same CATH topology
 5CHV A;  1MIR A;  4XR7 A;  7PCK A;  9PAP A;  2HH5 A;  3K24 A;  4W4U A;  3RVV A;  1HUC B;  1PPO A;  4XZX A;  3RVW A;  4CDC B;  1YK8 A;  2DJG B;  3CH2 X;  3B79 A;  3S3R A;  1A6R A;  1POP A;  1PXV A;  1QDQ A;  5EGW A;  2DCA A;  1QXP A;  4QRX A;  4YYW A;  2P7U A;  3N4C A;  2DOS A;  1U9V A;  3KWZ A;  1NPZ A;  4KLB A;  3H6S A;  2J7Q A;  5EZQ A;  2IPP B;  1KFU L;  4REZ A;  3LFY A;  3P5W A;  4QRG A;  3W30 A;  4RKX A;  3K8U A;  3BB7 A;  4P6E A;  1QMY A;  3PBH A;  3F5V A;  3O65 A;  3KWB X;  4BOQ A;  2YJC A;  4ZTB A;  1EWL A;  2BTW B;  4X6H A;  3HWN A;  2FYE A;  3C9E A;  1CJL A;  1U9Q X;  1ATK A;  3KX1 A;  3QT4 A;  1DEU A;  3H89 A;  1CS8 A;  4CDF B;  2FRQ A;  3PNR A;  1PVJ A;  4QRV A;  4Q8G A;  1F2C A;  1U9X A;  3E9S A;  3D6S A;  4OEL A;  3IHP A;  3P5V A;  1U5I A;  5CVN B;  2AYN A;  3MTV A;  4QBB A;  3IFU A;  1AU3 A;  3CH3 X;  2YJ8 A;  3RVX A;  5K16 A;  2NQI A;  1ZIV A;  3M99 A;  4RF0 A;  4X6I A;  1GCB A;  1FH0 A;  5EF4 A;  2NQG A;  4YYV A;  3BPF A;  3MHH A;  3IOQ A;  3TNX A;  3RNV A;  2VHF A;  1MS6 A;  4W5C A;  3ZNH A;  2DC7 A;  1NB5 A;  3WXG A;  4BS6 A;  2F1G A;  3ERV A;  3CBJ A;  3O1G A;  2DZZ A;  3TRK A;  1TU6 A;  2YJ2 A;  1ITO A;  1EWO A;  4CDE B;  1CTE A;  2XU3 A;  3I3T A;  4AXM A;  4AXL A;  4A5U A;  4BSQ A;  3KFQ A;  1PE6 A;  2AU1 A;  5JZE A;  3OF9 A;  1AU0 A;  3OQC A;  1AIM A;  4YYU A;  2FTD A;  4BOU A;  4N4Z A;  3MHS A;  2R9F A;  4RNA A;  3N3K A;  2FQ9 A;  2PNS A;  1DKI A;  2BDZ A;  2BDL A;  1ME3 A;  2R9M A;  1CSB B;  1SNK A;  1Y4H A;  1PCI A;  3MP2 A;  3QJ3 A;  1Q6K A;  2E01 A;  4MZS A;  3IMA A;  3IV2 A;  2R9O A;  3WXF A;  3USV A;  2DCC A;  5JH3 A;  3GCB A;  4OW0 A;  4FJC A;  2R9C A;  1CQD A;  2AVW A;  4MM3 B;  3MOR A;  3CBK A;  4D8E A;  5JA7 A;  3AI8 A;  3H8B A;  1THE A;  2NQA A;  2ARY A;  3PT2 A;  3P5U A;  4I05 A;  1GEC E;  3I06 A;  2HD5 A;  1GLO A;  4N79 A;  1NQC A;  1YVB A;  1KHP A;  3BOW A;  3W31 A;  2E03 A;  1ME4 A;  1STF E;  4OVZ A;  5A24 A;  1YT7 A;  2JRI A;  3MTN A;  1SP4 B;  2WBF X;  2DC6 A;  1DF0 A;  1PBH A;  1F2B A;  5FPW A;  2XU4 A;  1YK7 A;  2AYO A;  4ZUX U;  1F29 A;  3IEJ A;  4IP3 A;  4FK5 A;  3OF8 A;  4DMY A;  4HWY A;  1AU2 A;  3TMP A;  1NLJ A;  1MDW A;  1BY8 A;  1S4V A;  3QSD A;  1PPN A;  1BP4 A;  4G54 A;  6PAD A;  1AYV A;  2JQG R;  2HHN A;  2R6N A;  4CZW A;  5F02 A;  3BBA A;  1YZB A;  4WA6 A;  3ZUA A;  3OVX A;  2G8J A;  2FUD A;  5E6J A;  2C0Y A;  1YAL A;  2XU5 A;  1BQI A;  4YVA A;  3N3G A;  4D8I A;  3B21 A;  2NQD B;  3E1Z B;  1EF7 A;  1AEC A;  2FE8 A;  3KKU A;  3MJ5 A;  5J94 A;  3BC3 A;  2IBI A;  4W5B A;  2FRA A;  1JQP A;  1VJV A;  3KW9 A;  3BPM A;  2CIO A;  4M0W A;  2R9N A;  2AIM A;  2UZJ A;  2P0R A;  2AS8 A;  4D8B A;  4N8W A;  3PW3 A;  3V6C A;  2DJF B;  1KXR A;  1NL6 A;  1CPJ A;  3C0R A;  4YYR A;  3BY4 A;  1UKF A;  3NHE A;  1ICF A;  4MSX A;  3S3Q A;  1ZCM A;  4PT5 A;  1AYU A;  2YJ9 A;  1CB5 A;  2E02 A;  2DC9 A;  1PIP A;  2FO5 A;  3U8E A;  2GHU A;  3DF0 A;  4OEM A;  1EWP A;  1MEM A;  1NB3 A;  2YJB A;  4GUA A;  3PDF A;  4IUM A;  4FIP A;  4XUI A;  4BPV A;  3H8C A;  1O0E A;  2Y6E A;  5CVO B;  1CV8 A;  4BOP A;  3WXE A;  4BOS A;  3O0U A;  2P86 A;  3BCN A;  4DMX A;  2G7Y A;  3PHU A;  5PAD A;  2PBH A;  3IUT A;  4WUR A;  1X9Y A;  1PAD A;  3KSE A;  1GMY A;  1KHQ A;  4PP2 E;  1MHW A;  2OP3 A;  3OIS A;  3HHI A;  2DCD A;  1AU4 A;  3PSE A;  1VSN A;  2G8E A;  2BTW A;  1KFX L;  2E00 A;  2J7Q C;  2PAD A;  2ACT A;  4R3D A;  2GFO A;  2O6X A;  2DCB A;  4BS5 A;  4BOZ A;  3HD3 A;  4RY2 A;  5KO3 A;  2F7D A;  3BWK A;  2B1M A;  3PRM A;  2G6D A;  1IWD A;  2VHS A;  5CVM A;  3K9M A;  3V6E A;  1EWM A;  2H7J A;  5EZS A;  2FT2 A;  4YYQ A;  1F2A A;  4PAD A;  3H7D A;  1XKG A;  1TLO A;  5CHT A;  1M6D A;  3LXS A;  3OVZ A;  2HWK A;  2B1N A;  1U9W A;  4OVZ B;  4CDD B;  4PP1 A;  4RF1 A;  4YYS A;  4I07 A;  4BQV A;  1BGO A;  4P16 A;  2JTC A;  1Y08 A;  3PRP A;  4MZO A;  4MI7 A;  2BU3 A;  4I04 A;  3PHX A;  4Q8H A;  4X6J A;  2DZY A;  1AYW A;  4P6G A;  1MEG A;  4PI3 A;  2OZ2 A;  2AUZ A;  2AGA A;  4YV8 A;  4HXD B;  2PRE A;  1TL9 A;  2ATO A;  2OUL A;  2Z84 A;  4K7C A;  8PCH A;  3F75 A;  2CB5 A;  4QH6 A;  3HHA A;  3PHW A;  2AUX A;  2Y5B A;  1CVZ A;  2XU1 A;  3P5X A;  1PPD A;  2DC8 A;  1K3B B;  2JQF R;  2HXZ A;  1QOL A;  1PPP A; 
#chains in the Genus database with same CATH homology
 5CHV A;  1MIR A;  4XR7 A;  7PCK A;  9PAP A;  2HH5 A;  3K24 A;  4W4U A;  3RVV A;  1HUC B;  1PPO A;  3RVW A;  4CDC B;  1YK8 A;  2DJG B;  3CH2 X;  3B79 A;  3S3R A;  1A6R A;  1POP A;  1PXV A;  1QDQ A;  5EGW A;  2DCA A;  1QXP A;  4QRX A;  4YYW A;  2P7U A;  3N4C A;  1U9V A;  3KWZ A;  1NPZ A;  4KLB A;  3H6S A;  2IPP B;  1KFU L;  3LFY A;  3P5W A;  4QRG A;  4BGF A;  3K8U A;  4P6E A;  1QMY A;  3PBH A;  3F5V A;  3KWB X;  2YJC A;  4GUZ A;  4NV8 A;  1EWL A;  4X6H A;  3HWN A;  2FYE A;  3C9E A;  1CJL A;  1U9Q X;  1ATK A;  2BSZ A;  3KX1 A;  3D9W A;  3QT4 A;  1DEU A;  3H89 A;  1CS8 A;  4CDF B;  2FRQ A;  3PNR A;  4QRV A;  4Q8G A;  1F2C A;  1U9X A;  3D6S A;  4OEL A;  3IHP A;  3P5V A;  1U5I A;  5CVN B;  2AYN A;  4QBB A;  1AU3 A;  3CH3 X;  2YJ8 A;  3RVX A;  5K16 A;  2VFC A;  2NQI A;  1ZIV A;  3M99 A;  4X6I A;  1GCB A;  5EF4 A;  1FH0 A;  2NQG A;  4YYV A;  3BPF A;  3MHH A;  3IOQ A;  3TNX A;  2VHF A;  1MS6 A;  4W5C A;  2DC7 A;  1NB5 A;  3WXG A;  4BS6 A;  2F1G A;  3ERV A;  1E2T A;  3CBJ A;  3O1G A;  2DZZ A;  1TU6 A;  2YJ2 A;  1ITO A;  1EWO A;  4CDE B;  1CTE A;  2XU3 A;  3I3T A;  4AXM A;  4AXL A;  4BSQ A;  3KFQ A;  4NV7 A;  1PE6 A;  2AU1 A;  3OF9 A;  1AU0 A;  1AIM A;  4YYU A;  4B55 A;  2FTD A;  4N4Z A;  3MHS A;  2R9F A;  3N3K A;  2FQ9 A;  2PNS A;  2BDZ A;  2BDL A;  1ME3 A;  2R9M A;  1CSB B;  1SNK A;  1Y4H A;  1PCI A;  3QJ3 A;  1Q6K A;  2E01 A;  4MZS A;  3IMA A;  3IV2 A;  2R9O A;  3WXF A;  3USV A;  2DCC A;  5JH3 A;  3GCB A;  4FJC A;  2R9C A;  1CQD A;  2AVW A;  3MOR A;  3CBK A;  5JA7 A;  3AI8 A;  3H8B A;  1THE A;  2NQA A;  2ARY A;  3P5U A;  4I05 A;  1GEC E;  3I06 A;  2HD5 A;  1GLO A;  4N79 A;  1NQC A;  1YVB A;  1KHP A;  3BOW A;  2E03 A;  3LTW A;  1ME4 A;  1STF E;  5A24 A;  1YT7 A;  3MTN A;  1SP4 B;  2WBF X;  2DC6 A;  1DF0 A;  1PBH A;  1F2B A;  5FPW A;  2XU4 A;  1YK7 A;  2AYO A;  4ZUX U;  1F29 A;  3IEJ A;  4FK5 A;  3OF8 A;  4DMY A;  4HWY A;  1AU2 A;  1NLJ A;  1MDW A;  1BY8 A;  1S4V A;  3QSD A;  1PPN A;  1BP4 A;  4G54 A;  6PAD A;  1AYV A;  2JQG R;  2HHN A;  2R6N A;  4CZW A;  5F02 A;  4WA6 A;  3ZUA A;  3OVX A;  2G8J A;  2FUD A;  2C0Y A;  1YAL A;  2XU5 A;  1BQI A;  4YVA A;  3N3G A;  2NQD B;  3E1Z B;  1EF7 A;  1AEC A;  3KKU A;  5J94 A;  3BC3 A;  2IBI A;  4W5B A;  2FRA A;  1JQP A;  1VJV A;  3KW9 A;  3BPM A;  2CIO A;  2R9N A;  2AIM A;  2P0R A;  2AS8 A;  4N8W A;  3PW3 A;  3V6C A;  2DJF B;  1KXR A;  1NL6 A;  1CPJ A;  4YYR A;  3NHE A;  1ICF A;  4MSX A;  3S3Q A;  1ZCM A;  1AYU A;  2YJ9 A;  1CB5 A;  2E02 A;  2DC9 A;  1PIP A;  2FO5 A;  3U8E A;  2GHU A;  3DF0 A;  4OEM A;  1EWP A;  1MEM A;  1NB3 A;  2YJB A;  3PDF A;  4FIP A;  4XUI A;  4BPV A;  3H8C A;  1O0E A;  2Y6E A;  5CVO B;  1CV8 A;  3WXE A;  1W6F A;  3O0U A;  2P86 A;  3BCN A;  4DMX A;  2VFB A;  2G7Y A;  5PAD A;  2PBH A;  3IUT A;  1X9Y A;  1PAD A;  3KSE A;  1GMY A;  1KHQ A;  4PP2 E;  1MHW A;  2OP3 A;  3OIS A;  3HHI A;  2DCD A;  1AU4 A;  1VSN A;  2G8E A;  1KFX L;  2E00 A;  2PAD A;  2ACT A;  2GFO A;  2O6X A;  1W4T A;  2DCB A;  4BS5 A;  3HD3 A;  4RY2 A;  2F7D A;  3BWK A;  2B1M A;  2G6D A;  1IWD A;  2VHS A;  5CVM A;  3K9M A;  3V6E A;  1EWM A;  2H7J A;  2FT2 A;  4YYQ A;  1F2A A;  4PAD A;  3H7D A;  1XKG A;  1TLO A;  5CHT A;  1M6D A;  3LXS A;  3OVZ A;  2B1N A;  1U9W A;  4CDD B;  4PP1 A;  4YYS A;  4I07 A;  4BQV A;  1BGO A;  1Y08 A;  4MZO A;  1W5R A;  4I04 A;  4Q8H A;  4X6J A;  2DZY A;  1AYW A;  4P6G A;  1MEG A;  4PI3 A;  2OZ2 A;  2AUZ A;  4YV8 A;  4C5P A;  2PRE A;  1TL9 A;  2ATO A;  2OUL A;  4K7C A;  8PCH A;  3F75 A;  2CB5 A;  4QH6 A;  1GX3 A;  3HHA A;  2AUX A;  2Y5B A;  1CVZ A;  2XU1 A;  3P5X A;  1PPD A;  2DC8 A;  1K3B B;  2JQF R;  2HXZ A;  1QOL A;  1PPP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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