1CS8A

Crystal structure of procathepsin l
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
316
structure length
315
Chain Sequence
SLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDAGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords HUMAN PROCATHEPSIN L
publication title Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment.
pubmed rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 63
structure length 315
sequence length 316
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 1999-08-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
A PF08246 Inhibitor_I29 Cathepsin propeptide inhibitor domain (I29)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1cs8A00
4YYSA 4PI3A 1CPJA 1QDQA 5FPWA 1NL6A 3NHEA 1BY8A 1GCBA 2HD5A 2GFOA 3HWNA 3K9MA 1K3BB 3BPFA 1BP4A 1KHPA 1CJLA 1QXPA 4PADA 1YALA 2FO5A 4RY2A 3RVXA 4MZSA 1CV8A 1PPPA 4W5CA 3H7DA 2AS8A 5CVOB 3PNRA 2R9NA 1PPDA 4X6IA 2YJ9A 3P5XA 1MHWA 2XU3A 3V6CA 3WXFA 4CZWA 6PADA 4X6HA 1POPA 1THEA 2ACTA 2DJGB 2G7YA 2R6NA 3N3GA 1STFE 4MZOA 1O0EA 4DMYA 3M99A 3P5WA 3KWBX 1CTEA 2IBIA 1MIRA 2P0RA 1EWLA 1AYWA 1NB5A 1KFUL 2F7DA 1CB5A 2ATOA 1HUCB 2Y6EA 2OP3A 3PDFA 4K7CA 1EWPA 2VHFA 3LFYA 1EWOA 1MDWA 3CBJA 2OZ2A 2NQDB 2B1NA 2DC9A 1NB3A 2VHSA 3RVWA 2C0YA 3MHHA 3BPMA 3PW3A 1SP4B 4BQVA 4DMXA 1QMYA 3KWZA 2G6DA 4I05A 2G8EA 3IMAA 3BWKA 3MORA 5J94A 4I07A 2WBFX 1Q6KA 3KW9A 1F2CA 1NPZA 1EF7A 3GCBA 4BSQA 3RVVA 4P6EA 3P5UA 2AIMA 2IPPB 2AU1A 4CDCB 5CHTA 2AVWA 4XUIA 2AYNA 2PADA 4X6JA 2NQAA 1PADA 3KX1A 1AU4A 2NQGA 3MTNA 5A24A 4XR7A 1KHQA 1GECE 1PE6A 2CB5A 4BPVA 1U9VA 2DC6A 3HHAA 1AU3A 3QT4A 3USVA 2OULA 3K24A 4AXLA 4ZUXU 4W5BA 4N4ZA 1PPOA 2DZZA 1BQIA 3OF9A 2PBHA 3O1GA 1TU6A 1A6RA 2FT2A 3N4CA 3CH3X 3F5VA 4BS6A 1EWMA 2XU4A 3QJ3A 2BDLA 3C9EA 1ITOA 1AYUA 4Q8GA 4YV8A 2YJCA 1MEGA 3S3QA 2YJ2A 9PAPA 1QOLA 3ERVA 1PCIA 3LXSA 4I04A 4N79A 2JQFR 1AU0A 2R9FA 1DF0A 5F02A 4W4UA 1M6DA 1PBHA 3WXEA 4YVAA 3PBHA 3TNXA 4OEMA 2JQGR 4P6GA 4Q8HA 2DJFB 3HHIA 4OELA 3N3KA 3V6EA 2AUXA 3I06A 4PP1A 2FQ9A 2YJBA 3OISA 3H8CA 4YYVA 1JQPA 1ZCMA 1YK8A 3KKUA 1PPNA 1YT7A 3IHPA 4QRVA 1PIPA 3KFQA 2Y5BA 1KXRA 1CSBB 2XU5A 3ZUAA 2DCCA 3CH2X 3H8BA 5CVMA 4YYRA 1F2AA 2E03A 4QBBA 1AECA 2FUDA 3IEJA 1XKGA 1YVBA 2CIOA 1ZIVA 1Y4HA 2HH5A 2P7UA 2DCAA 3H6SA 3BOWA 1S4VA 2FRAA 2HHNA 1F29A 2YJ8A 4MSXA 4QRXA 1DEUA 4HWYA 1U5IA 3KSEA 4N8WA 3WXGA 2FRQA 2R9MA 2G8JA 1ME4A 1MEMA 2GHUA 1CQDA 3D6SA 1SNKA 3P5VA 5JH3A 3K8UA 2ARYA 2E02A 2NQIA 3I3TA 1ME3A 3IV2A 2FTDA 3QSDA 3H89A 2E00A 2PREA 1U9XA 3OF8A 4PP2E 2F1GA 1CS8A 4KLBA 2PNSA 4CDFB 5EGWA 2B1MA 3IOQA 1IWDA 1X9YA 1MS6A 2E01A 2AUZA 4G54A 1NLJA 1TL9A 1KFXL 1BGOA 2HXZA 2DZYA 2BDZA 1AIMA 1ATKA 3B79A 3O0UA 3MHSA 1NQCA 5CVNB 1U9QX 3S3RA 3IUTA 2R9CA 2P86A 2DCBA 4FK5A 1VSNA 1FH0A 1TLOA 1Y08A 1AU2A 4YYWA 2H7JA 2R9OA 1PXVA 3BCNA 2DC8A 3E1ZB 2XU1A 4QRGA 3AI8A 3OVXA 4YYQA 1GLOA 2AYOA 7PCKA 2DCDA 2O6XA 1U9WA 2DC7A 4FIPA 5PADA 3F75A 3HD3A 4YYUA 4BS5A 2FYEA 4CDEB 4QH6A 5K16A 3U8EA 4FJCA 3OVZA 3BC3A 3CBKA 1VJVA 5JA7A 1ICFA 3DF0A 4CDDB 1YK7A 5EF4A 1CVZA 8PCHA 4AXMA 1GMYA 4WA6A 1AYVA 1F2BA 5CHVA
chains in the Genus database with same CATH superfamily
3O65A 4YYSA 4PI3A 1CPJA 1QDQA 5FPWA 1NL6A 3NHEA 1BY8A 1GCBA 2HD5A 2GFOA 3HWNA 3K9MA 1K3BB 3BPFA 1BP4A 4RF1A 1KHPA 1CJLA 1QXPA 4MM3B 1YALA 4PADA 2FO5A 2J7QC 4RY2A 3RVXA 3MTVA 3BBAA 4MZSA 1CV8A 1PPPA 4W5CA 3H7DA 2AS8A 5CVOB 3PNRA 2R9NA 4BOUA 1PPDA 4X6IA 2YJ9A 4PT5A 3P5XA 1MHWA 4R3DA 2XU3A 3V6CA 3WXFA 3BB7A 3ZNHA 4CZWA 6PADA 3PRMA 4X6HA 1POPA 1THEA 2ACTA 2DJGB 2G7YA 2R6NA 5EZSA 3N3GA 1STFE 4MZOA 1O0EA 4DMYA 2BTWA 3M99A 3P5WA 3KWBX 1CTEA 2IBIA 1MIRA 2P0RA 1EWLA 1AYWA 1NB5A 1KFUL 2F7DA 1CB5A 2ATOA 3OQCA 1HUCB 2Y6EA 2OP3A 3PDFA 4K7CA 1EWPA 2VHFA 3BY4A 2DOSA 3LFYA 1EWOA 4ZTBA 1MDWA 3CBJA 3PHWA 2OZ2A 4BOQA 2NQDB 2B1NA 2DC9A 1NB3A 2VHSA 4BOSA 3RVWA 2C0YA 3MHHA 3BPMA 3PW3A 1SP4B 4BOZA 4BQVA 4DMXA 2BU3A 3TRKA 1QMYA 3KWZA 4A5UA 2G6DA 2UZJA 4I05A 2G8EA 3IMAA 3RNVA 4IUMA 3BWKA 3MORA 2AGAA 5J94A 4I07A 3W31A 2WBFX 4OVZA 1Q6KA 3KW9A 1F2CA 1NPZA 1EF7A 3GCBA 4BSQA 3RVVA 4P6EA 3P5UA 2AIMA 2IPPB 2AU1A 4CDCB 5CHTA 2AVWA 4XUIA 2AYNA 2PADA 4X6JA 2NQAA 1PADA 3KX1A 1AU4A 2NQGA 3MTNA 5A24A 4XR7A 1KHQA 2FE8A 3W30A 1GECE 1PE6A 2CB5A 4BPVA 1U9VA 2DC6A 3HHAA 1AU3A 3QT4A 3USVA 2OULA 3PRPA 2HWKA 3K24A 4AXLA 4ZUXU 3IFUA 4W5BA 4RKXA 4N4ZA 1PPOA 2DZZA 1BQIA 3OF9A 2PBHA 3O1GA 4XZXA 1TU6A 1A6RA 2FT2A 2BTWB 3N4CA 3CH3X 3F5VA 4BS6A 1EWMA 2XU4A 3QJ3A 5JZEA 2BDLA 3C9EA 1ITOA 4M0WA 1AYUA 4Q8GA 4YV8A 2YJCA 1MEGA 3S3QA 2YJ2A 9PAPA 1QOLA 3ERVA 1PCIA 3LXSA 4I04A 4N79A 2JQFR 1AU0A 2R9FA 1DF0A 5F02A 4W4UA 1M6DA 5E6JA 1PBHA 3WXEA 4YVAA 3PBHA 4WURA 2JRIA 3TNXA 4OEMA 2JQGR 4P6GA 4Q8HA 2DJFB 3HHIA 4IP3A 3MJ5A 4OELA 3N3KA 3V6EA 2AUXA 3I06A 4PP1A 2FQ9A 2YJBA 3OISA 3H8CA 4YYVA 1JQPA 1ZCMA 3MP2A 1YK8A 4BOPA 3KKUA 1PPNA 1YT7A 3IHPA 3PHUA 4QRVA 1PIPA 3KFQA 2Y5BA 1KXRA 1CSBB 2XU5A 4D8IA 3ZUAA 2DCCA 3CH2X 3H8BA 5CVMA 4YYRA 1F2AA 2E03A 4QBBA 1AECA 2JTCA 2FUDA 3IEJA 1XKGA 1YVBA 2CIOA 1ZIVA 1Y4HA 2HH5A 2P7UA 2DCAA 3H6SA 3BOWA 1S4VA 2FRAA 2HHNA 3PSEA 1F29A 2YJ8A 4MSXA 4QRXA 1DEUA 4HWYA 1U5IA 4GUAA 3KSEA 4N8WA 3WXGA 2FRQA 2R9MA 2J7QA 2G8JA 4RNAA 1ME4A 1MEMA 2GHUA 1CQDA 3D6SA 1SNKA 3P5VA 5JH3A 5KO3A 3K8UA 2ARYA 2E02A 3B21A 2NQIA 3I3TA 1ME3A 3IV2A 4P16A 2FTDA 3QSDA 3H89A 2E00A 2PREA 1U9XA 3OF8A 3TMPA 4PP2E 2F1GA 4MI7A 1CS8A 4KLBA 2PNSA 4CDFB 5EGWA 2B1MA 3IOQA 1IWDA 1UKFA 1X9YA 1MS6A 2E01A 2AUZA 1PVJA 4G54A 1NLJA 1TL9A 1KFXL 1BGOA 3PHXA 2HXZA 2DZYA 2BDZA 1AIMA 1ATKA 3B79A 3O0UA 3MHSA 1NQCA 5CVNB 4D8BA 1DKIA 1U9QX 3S3RA 4OW0A 3IUTA 2R9CA 2P86A 5EZQA 2DCBA 4FK5A 1VSNA 1FH0A 1TLOA 1Y08A 1AU2A 4YYWA 2H7JA 2R9OA 1PXVA 3BCNA 2DC8A 3E1ZB 2XU1A 4QRGA 3AI8A 4OVZB 3OVXA 4YYQA 1GLOA 2AYOA 7PCKA 2DCDA 2O6XA 1U9WA 2DC7A 4FIPA 5PADA 3F75A 3HD3A 4YYUA 4BS5A 1YZBA 2FYEA 4CDEB 4QH6A 4REZA 5K16A 3U8EA 4FJCA 3OVZA 3BC3A 3C0RA 3CBKA 1VJVA 2Z84A 5JA7A 1ICFA 3DF0A 4CDDB 1YK7A 4D8EA 5EF4A 1CVZA 8PCHA 3PT2A 4HXDB 4AXMA 4RF0A 1GMYA 4WA6A 1AYVA 3E9SA 1F2BA 5CHVA
chains in the Genus database with same CATH topology
4YYSA 4PI3A 1CPJA 1QDQA 5FPWA 1NL6A 3NHEA 1BY8A 1GCBA 2HD5A 2GFOA 3HWNA 3K9MA 1K3BB 3BPFA 1BP4A 1KHPA 1CJLA 1QXPA 4PADA 1YALA 2FO5A 4RY2A 3RVXA 4MZSA 1CV8A 1PPPA 4W5CA 3H7DA 2AS8A 5CVOB 3PNRA 2R9NA 1PPDA 4X6IA 3D9WA 2YJ9A 3P5XA 1MHWA 2XU3A 3V6CA 3WXFA 4CZWA 6PADA 1E2TA 4X6HA 1W4TA 1POPA 1THEA 2ACTA 2DJGB 2G7YA 2R6NA 3N3GA 1STFE 4MZOA 1O0EA 4DMYA 3M99A 3P5WA 3KWBX 1CTEA 2IBIA 1MIRA 2P0RA 1EWLA 1AYWA 1NB5A 1KFUL 2F7DA 1CB5A 2ATOA 1HUCB 2Y6EA 2OP3A 3PDFA 4K7CA 1EWPA 2VHFA 3LFYA 1EWOA 1MDWA 3CBJA 2OZ2A 2NQDB 2B1NA 2DC9A 1NB3A 2VHSA 3RVWA 2C0YA 3MHHA 3BPMA 3PW3A 1SP4B 4BQVA 4DMXA 1QMYA 3KWZA 2G6DA 4I05A 2G8EA 3IMAA 3BWKA 3MORA 5J94A 4I07A 2WBFX 1Q6KA 3KW9A 1F2CA 1NPZA 1EF7A 3GCBA 4BSQA 3RVVA 4P6EA 3P5UA 2AIMA 2IPPB 2AU1A 4CDCB 5CHTA 2AVWA 4XUIA 2AYNA 2PADA 4X6JA 2NQAA 1PADA 2VFBA 3KX1A 1AU4A 2NQGA 3MTNA 5A24A 4XR7A 1KHQA 1GECE 1PE6A 2CB5A 4BPVA 1U9VA 2DC6A 3HHAA 1AU3A 3QT4A 3USVA 2OULA 3K24A 4AXLA 4ZUXU 4W5BA 4N4ZA 1PPOA 4NV8A 2DZZA 1BQIA 3OF9A 2PBHA 3O1GA 1TU6A 1A6RA 2FT2A 3N4CA 3CH3X 3F5VA 4BS6A 1EWMA 2XU4A 3QJ3A 2BDLA 3C9EA 1ITOA 1AYUA 4Q8GA 4YV8A 2YJCA 1MEGA 3S3QA 2YJ2A 9PAPA 1QOLA 3ERVA 1PCIA 3LXSA 4I04A 4N79A 2JQFR 1AU0A 2R9FA 1DF0A 5F02A 4W4UA 1M6DA 1PBHA 3WXEA 4YVAA 3PBHA 3TNXA 4OEMA 2JQGR 4P6GA 4Q8HA 2DJFB 3HHIA 4OELA 3N3KA 3V6EA 2AUXA 3I06A 4PP1A 2FQ9A 2YJBA 3OISA 3H8CA 4YYVA 1JQPA 1ZCMA 1YK8A 1GX3A 3KKUA 1PPNA 1YT7A 3IHPA 4QRVA 1PIPA 3KFQA 2Y5BA 1KXRA 1CSBB 2XU5A 3ZUAA 2DCCA 3CH2X 3H8BA 5CVMA 4C5PA 4YYRA 1F2AA 2E03A 4QBBA 1AECA 2FUDA 3IEJA 1XKGA 1YVBA 2CIOA 1ZIVA 1Y4HA 2HH5A 2P7UA 2DCAA 3H6SA 3BOWA 1S4VA 2FRAA 2HHNA 1F29A 2YJ8A 4MSXA 4QRXA 1DEUA 4HWYA 1U5IA 3KSEA 4BGFA 4N8WA 3WXGA 2FRQA 2R9MA 2G8JA 1ME4A 1MEMA 2GHUA 1CQDA 3D6SA 1SNKA 3P5VA 5JH3A 3K8UA 2ARYA 2E02A 2NQIA 3I3TA 1ME3A 3IV2A 2FTDA 3QSDA 3H89A 2E00A 2PREA 1U9XA 3OF8A 4PP2E 2F1GA 2BSZA 1CS8A 4KLBA 2PNSA 4CDFB 5EGWA 2B1MA 3IOQA 1W6FA 1IWDA 1X9YA 1MS6A 2E01A 2AUZA 4G54A 1NLJA 1TL9A 1KFXL 1BGOA 2HXZA 2DZYA 2BDZA 1AIMA 1ATKA 3B79A 3O0UA 3MHSA 1NQCA 5CVNB 1U9QX 3S3RA 3IUTA 2R9CA 2P86A 2DCBA 4GUZA 4FK5A 1VSNA 1FH0A 1TLOA 1Y08A 1AU2A 4YYWA 2H7JA 2R9OA 1PXVA 3BCNA 2DC8A 3E1ZB 2XU1A 4QRGA 3AI8A 3OVXA 4YYQA 2VFCA 1GLOA 2AYOA 7PCKA 4B55A 1W5RA 2DCDA 2O6XA 1U9WA 2DC7A 4FIPA 5PADA 3F75A 3HD3A 4YYUA 4BS5A 2FYEA 4CDEB 4QH6A 5K16A 3U8EA 4FJCA 3OVZA 3BC3A 3CBKA 4NV7A 1VJVA 5JA7A 1ICFA 3DF0A 4CDDB 1YK7A 5EF4A 1CVZA 8PCHA 3LTWA 4AXMA 1GMYA 4WA6A 1AYVA 1F2BA 5CHVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YYS A;  4PI3 A;  1CPJ A;  1QDQ A;  5FPW A;  1NL6 A;  3NHE A;  1BY8 A;  1GCB A;  2HD5 A;  2GFO A;  3HWN A;  3K9M A;  1K3B B;  3BPF A;  1BP4 A;  1KHP A;  1CJL A;  1QXP A;  4PAD A;  1YAL A;  2FO5 A;  4RY2 A;  3RVX A;  4MZS A;  1CV8 A;  1PPP A;  4W5C A;  3H7D A;  2AS8 A;  5CVO B;  3PNR A;  2R9N A;  1PPD A;  4X6I A;  2YJ9 A;  3P5X A;  1MHW A;  2XU3 A;  3V6C A;  3WXF A;  4CZW A;  6PAD A;  4X6H A;  1POP A;  1THE A;  2ACT A;  2DJG B;  2G7Y A;  2R6N A;  3N3G A;  1STF E;  4MZO A;  1O0E A;  4DMY A;  3M99 A;  3P5W A;  3KWB X;  1CTE A;  2IBI A;  1MIR A;  2P0R A;  1EWL A;  1AYW A;  1NB5 A;  1KFU L;  2F7D A;  1CB5 A;  2ATO A;  1HUC B;  2Y6E A;  2OP3 A;  3PDF A;  4K7C A;  1EWP A;  2VHF A;  3LFY A;  1EWO A;  1MDW A;  3CBJ A;  2OZ2 A;  2NQD B;  2B1N A;  2DC9 A;  1NB3 A;  2VHS A;  3RVW A;  2C0Y A;  3MHH A;  3BPM A;  3PW3 A;  1SP4 B;  4BQV A;  4DMX A;  1QMY A;  3KWZ A;  2G6D A;  4I05 A;  2G8E A;  3IMA A;  3BWK A;  3MOR A;  5J94 A;  4I07 A;  2WBF X;  1Q6K A;  3KW9 A;  1F2C A;  1NPZ A;  1EF7 A;  3GCB A;  4BSQ A;  3RVV A;  4P6E A;  3P5U A;  2AIM A;  2IPP B;  2AU1 A;  4CDC B;  5CHT A;  2AVW A;  4XUI A;  2AYN A;  2PAD A;  4X6J A;  2NQA A;  1PAD A;  3KX1 A;  1AU4 A;  2NQG A;  3MTN A;  5A24 A;  4XR7 A;  1KHQ A;  1GEC E;  1PE6 A;  2CB5 A;  4BPV A;  1U9V A;  2DC6 A;  3HHA A;  1AU3 A;  3QT4 A;  3USV A;  2OUL A;  3K24 A;  4AXL A;  4ZUX U;  4W5B A;  4N4Z A;  1PPO A;  2DZZ A;  1BQI A;  3OF9 A;  2PBH A;  3O1G A;  1TU6 A;  1A6R A;  2FT2 A;  3N4C A;  3CH3 X;  3F5V A;  4BS6 A;  1EWM A;  2XU4 A;  3QJ3 A;  2BDL A;  3C9E A;  1ITO A;  1AYU A;  4Q8G A;  4YV8 A;  2YJC A;  1MEG A;  3S3Q A;  2YJ2 A;  9PAP A;  1QOL A;  3ERV A;  1PCI A;  3LXS A;  4I04 A;  4N79 A;  2JQF R;  1AU0 A;  2R9F A;  1DF0 A;  5F02 A;  4W4U A;  1M6D A;  1PBH A;  3WXE A;  4YVA A;  3PBH A;  3TNX A;  4OEM A;  2JQG R;  4P6G A;  4Q8H A;  2DJF B;  3HHI A;  4OEL A;  3N3K A;  3V6E A;  2AUX A;  3I06 A;  4PP1 A;  2FQ9 A;  2YJB A;  3OIS A;  3H8C A;  4YYV A;  1JQP A;  1ZCM A;  1YK8 A;  3KKU A;  1PPN A;  1YT7 A;  3IHP A;  4QRV A;  1PIP A;  3KFQ A;  2Y5B A;  1KXR A;  1CSB B;  2XU5 A;  3ZUA A;  2DCC A;  3CH2 X;  3H8B A;  5CVM A;  4YYR A;  1F2A A;  2E03 A;  4QBB A;  1AEC A;  2FUD A;  3IEJ A;  1XKG A;  1YVB A;  2CIO A;  1ZIV A;  1Y4H A;  2HH5 A;  2P7U A;  2DCA A;  3H6S A;  3BOW A;  1S4V A;  2FRA A;  2HHN A;  1F29 A;  2YJ8 A;  4MSX A;  4QRX A;  1DEU A;  4HWY A;  1U5I A;  3KSE A;  4N8W A;  3WXG A;  2FRQ A;  2R9M A;  2G8J A;  1ME4 A;  1MEM A;  2GHU A;  1CQD A;  3D6S A;  1SNK A;  3P5V A;  5JH3 A;  3K8U A;  2ARY A;  2E02 A;  2NQI A;  3I3T A;  1ME3 A;  3IV2 A;  2FTD A;  3QSD A;  3H89 A;  2E00 A;  2PRE A;  1U9X A;  3OF8 A;  4PP2 E;  2F1G A;  1CS8 A;  4KLB A;  2PNS A;  4CDF B;  5EGW A;  2B1M A;  3IOQ A;  1IWD A;  1X9Y A;  1MS6 A;  2E01 A;  2AUZ A;  4G54 A;  1NLJ A;  1TL9 A;  1KFX L;  1BGO A;  2HXZ A;  2DZY A;  2BDZ A;  1AIM A;  1ATK A;  3B79 A;  3O0U A;  3MHS A;  1NQC A;  5CVN B;  1U9Q X;  3S3R A;  3IUT A;  2R9C A;  2P86 A;  2DCB A;  4FK5 A;  1VSN A;  1FH0 A;  1TLO A;  1Y08 A;  1AU2 A;  4YYW A;  2H7J A;  2R9O A;  1PXV A;  3BCN A;  2DC8 A;  3E1Z B;  2XU1 A;  4QRG A;  3AI8 A;  3OVX A;  4YYQ A;  1GLO A;  2AYO A;  7PCK A;  2DCD A;  2O6X A;  1U9W A;  2DC7 A;  4FIP A;  5PAD A;  3F75 A;  3HD3 A;  4YYU A;  4BS5 A;  2FYE A;  4CDE B;  4QH6 A;  5K16 A;  3U8E A;  4FJC A;  3OVZ A;  3BC3 A;  3CBK A;  1VJV A;  5JA7 A;  1ICF A;  3DF0 A;  4CDD B;  1YK7 A;  5EF4 A;  1CVZ A;  8PCH A;  4AXM A;  1GMY A;  4WA6 A;  1AYV A;  1F2B A;  5CHV A; 
#chains in the Genus database with same CATH topology
 3O65 A;  4YYS A;  4PI3 A;  1CPJ A;  1QDQ A;  5FPW A;  1NL6 A;  3NHE A;  1BY8 A;  1GCB A;  2HD5 A;  2GFO A;  3HWN A;  3K9M A;  1K3B B;  3BPF A;  1BP4 A;  4RF1 A;  1KHP A;  1CJL A;  1QXP A;  4MM3 B;  1YAL A;  4PAD A;  2FO5 A;  2J7Q C;  4RY2 A;  3RVX A;  3MTV A;  3BBA A;  4MZS A;  1CV8 A;  1PPP A;  4W5C A;  3H7D A;  2AS8 A;  5CVO B;  3PNR A;  2R9N A;  4BOU A;  1PPD A;  4X6I A;  2YJ9 A;  4PT5 A;  3P5X A;  1MHW A;  4R3D A;  2XU3 A;  3V6C A;  3WXF A;  3BB7 A;  3ZNH A;  4CZW A;  6PAD A;  3PRM A;  4X6H A;  1POP A;  1THE A;  2ACT A;  2DJG B;  2G7Y A;  2R6N A;  5EZS A;  3N3G A;  1STF E;  4MZO A;  1O0E A;  4DMY A;  2BTW A;  3M99 A;  3P5W A;  3KWB X;  1CTE A;  2IBI A;  1MIR A;  2P0R A;  1EWL A;  1AYW A;  1NB5 A;  1KFU L;  2F7D A;  1CB5 A;  2ATO A;  3OQC A;  1HUC B;  2Y6E A;  2OP3 A;  3PDF A;  4K7C A;  1EWP A;  2VHF A;  3BY4 A;  2DOS A;  3LFY A;  1EWO A;  4ZTB A;  1MDW A;  3CBJ A;  3PHW A;  2OZ2 A;  4BOQ A;  2NQD B;  2B1N A;  2DC9 A;  1NB3 A;  2VHS A;  4BOS A;  3RVW A;  2C0Y A;  3MHH A;  3BPM A;  3PW3 A;  1SP4 B;  4BOZ A;  4BQV A;  4DMX A;  2BU3 A;  3TRK A;  1QMY A;  3KWZ A;  4A5U A;  2G6D A;  2UZJ A;  4I05 A;  2G8E A;  3IMA A;  3RNV A;  4IUM A;  3BWK A;  3MOR A;  2AGA A;  5J94 A;  4I07 A;  3W31 A;  2WBF X;  4OVZ A;  1Q6K A;  3KW9 A;  1F2C A;  1NPZ A;  1EF7 A;  3GCB A;  4BSQ A;  3RVV A;  4P6E A;  3P5U A;  2AIM A;  2IPP B;  2AU1 A;  4CDC B;  5CHT A;  2AVW A;  4XUI A;  2AYN A;  2PAD A;  4X6J A;  2NQA A;  1PAD A;  3KX1 A;  1AU4 A;  2NQG A;  3MTN A;  5A24 A;  4XR7 A;  1KHQ A;  2FE8 A;  3W30 A;  1GEC E;  1PE6 A;  2CB5 A;  4BPV A;  1U9V A;  2DC6 A;  3HHA A;  1AU3 A;  3QT4 A;  3USV A;  2OUL A;  3PRP A;  2HWK A;  3K24 A;  4AXL A;  4ZUX U;  3IFU A;  4W5B A;  4RKX A;  4N4Z A;  1PPO A;  2DZZ A;  1BQI A;  3OF9 A;  2PBH A;  3O1G A;  4XZX A;  1TU6 A;  1A6R A;  2FT2 A;  2BTW B;  3N4C A;  3CH3 X;  3F5V A;  4BS6 A;  1EWM A;  2XU4 A;  3QJ3 A;  5JZE A;  2BDL A;  3C9E A;  1ITO A;  4M0W A;  1AYU A;  4Q8G A;  4YV8 A;  2YJC A;  1MEG A;  3S3Q A;  2YJ2 A;  9PAP A;  1QOL A;  3ERV A;  1PCI A;  3LXS A;  4I04 A;  4N79 A;  2JQF R;  1AU0 A;  2R9F A;  1DF0 A;  5F02 A;  4W4U A;  1M6D A;  5E6J A;  1PBH A;  3WXE A;  4YVA A;  3PBH A;  4WUR A;  2JRI A;  3TNX A;  4OEM A;  2JQG R;  4P6G A;  4Q8H A;  2DJF B;  3HHI A;  4IP3 A;  3MJ5 A;  4OEL A;  3N3K A;  3V6E A;  2AUX A;  3I06 A;  4PP1 A;  2FQ9 A;  2YJB A;  3OIS A;  3H8C A;  4YYV A;  1JQP A;  1ZCM A;  3MP2 A;  1YK8 A;  4BOP A;  3KKU A;  1PPN A;  1YT7 A;  3IHP A;  3PHU A;  4QRV A;  1PIP A;  3KFQ A;  2Y5B A;  1KXR A;  1CSB B;  2XU5 A;  4D8I A;  3ZUA A;  2DCC A;  3CH2 X;  3H8B A;  5CVM A;  4YYR A;  1F2A A;  2E03 A;  4QBB A;  1AEC A;  2JTC A;  2FUD A;  3IEJ A;  1XKG A;  1YVB A;  2CIO A;  1ZIV A;  1Y4H A;  2HH5 A;  2P7U A;  2DCA A;  3H6S A;  3BOW A;  1S4V A;  2FRA A;  2HHN A;  3PSE A;  1F29 A;  2YJ8 A;  4MSX A;  4QRX A;  1DEU A;  4HWY A;  1U5I A;  4GUA A;  3KSE A;  4N8W A;  3WXG A;  2FRQ A;  2R9M A;  2J7Q A;  2G8J A;  4RNA A;  1ME4 A;  1MEM A;  2GHU A;  1CQD A;  3D6S A;  1SNK A;  3P5V A;  5JH3 A;  5KO3 A;  3K8U A;  2ARY A;  2E02 A;  3B21 A;  2NQI A;  3I3T A;  1ME3 A;  3IV2 A;  4P16 A;  2FTD A;  3QSD A;  3H89 A;  2E00 A;  2PRE A;  1U9X A;  3OF8 A;  3TMP A;  4PP2 E;  2F1G A;  4MI7 A;  1CS8 A;  4KLB A;  2PNS A;  4CDF B;  5EGW A;  2B1M A;  3IOQ A;  1IWD A;  1UKF A;  1X9Y A;  1MS6 A;  2E01 A;  2AUZ A;  1PVJ A;  4G54 A;  1NLJ A;  1TL9 A;  1KFX L;  1BGO A;  3PHX A;  2HXZ A;  2DZY A;  2BDZ A;  1AIM A;  1ATK A;  3B79 A;  3O0U A;  3MHS A;  1NQC A;  5CVN B;  4D8B A;  1DKI A;  1U9Q X;  3S3R A;  4OW0 A;  3IUT A;  2R9C A;  2P86 A;  5EZQ A;  2DCB A;  4FK5 A;  1VSN A;  1FH0 A;  1TLO A;  1Y08 A;  1AU2 A;  4YYW A;  2H7J A;  2R9O A;  1PXV A;  3BCN A;  2DC8 A;  3E1Z B;  2XU1 A;  4QRG A;  3AI8 A;  4OVZ B;  3OVX A;  4YYQ A;  1GLO A;  2AYO A;  7PCK A;  2DCD A;  2O6X A;  1U9W A;  2DC7 A;  4FIP A;  5PAD A;  3F75 A;  3HD3 A;  4YYU A;  4BS5 A;  1YZB A;  2FYE A;  4CDE B;  4QH6 A;  4REZ A;  5K16 A;  3U8E A;  4FJC A;  3OVZ A;  3BC3 A;  3C0R A;  3CBK A;  1VJV A;  2Z84 A;  5JA7 A;  1ICF A;  3DF0 A;  4CDD B;  1YK7 A;  4D8E A;  5EF4 A;  1CVZ A;  8PCH A;  3PT2 A;  4HXD B;  4AXM A;  4RF0 A;  1GMY A;  4WA6 A;  1AYV A;  3E9S A;  1F2B A;  5CHV A; 
#chains in the Genus database with same CATH homology
 4YYS A;  4PI3 A;  1CPJ A;  1QDQ A;  5FPW A;  1NL6 A;  3NHE A;  1BY8 A;  1GCB A;  2HD5 A;  2GFO A;  3HWN A;  3K9M A;  1K3B B;  3BPF A;  1BP4 A;  1KHP A;  1CJL A;  1QXP A;  4PAD A;  1YAL A;  2FO5 A;  4RY2 A;  3RVX A;  4MZS A;  1CV8 A;  1PPP A;  4W5C A;  3H7D A;  2AS8 A;  5CVO B;  3PNR A;  2R9N A;  1PPD A;  4X6I A;  3D9W A;  2YJ9 A;  3P5X A;  1MHW A;  2XU3 A;  3V6C A;  3WXF A;  4CZW A;  6PAD A;  1E2T A;  4X6H A;  1W4T A;  1POP A;  1THE A;  2ACT A;  2DJG B;  2G7Y A;  2R6N A;  3N3G A;  1STF E;  4MZO A;  1O0E A;  4DMY A;  3M99 A;  3P5W A;  3KWB X;  1CTE A;  2IBI A;  1MIR A;  2P0R A;  1EWL A;  1AYW A;  1NB5 A;  1KFU L;  2F7D A;  1CB5 A;  2ATO A;  1HUC B;  2Y6E A;  2OP3 A;  3PDF A;  4K7C A;  1EWP A;  2VHF A;  3LFY A;  1EWO A;  1MDW A;  3CBJ A;  2OZ2 A;  2NQD B;  2B1N A;  2DC9 A;  1NB3 A;  2VHS A;  3RVW A;  2C0Y A;  3MHH A;  3BPM A;  3PW3 A;  1SP4 B;  4BQV A;  4DMX A;  1QMY A;  3KWZ A;  2G6D A;  4I05 A;  2G8E A;  3IMA A;  3BWK A;  3MOR A;  5J94 A;  4I07 A;  2WBF X;  1Q6K A;  3KW9 A;  1F2C A;  1NPZ A;  1EF7 A;  3GCB A;  4BSQ A;  3RVV A;  4P6E A;  3P5U A;  2AIM A;  2IPP B;  2AU1 A;  4CDC B;  5CHT A;  2AVW A;  4XUI A;  2AYN A;  2PAD A;  4X6J A;  2NQA A;  1PAD A;  2VFB A;  3KX1 A;  1AU4 A;  2NQG A;  3MTN A;  5A24 A;  4XR7 A;  1KHQ A;  1GEC E;  1PE6 A;  2CB5 A;  4BPV A;  1U9V A;  2DC6 A;  3HHA A;  1AU3 A;  3QT4 A;  3USV A;  2OUL A;  3K24 A;  4AXL A;  4ZUX U;  4W5B A;  4N4Z A;  1PPO A;  4NV8 A;  2DZZ A;  1BQI A;  3OF9 A;  2PBH A;  3O1G A;  1TU6 A;  1A6R A;  2FT2 A;  3N4C A;  3CH3 X;  3F5V A;  4BS6 A;  1EWM A;  2XU4 A;  3QJ3 A;  2BDL A;  3C9E A;  1ITO A;  1AYU A;  4Q8G A;  4YV8 A;  2YJC A;  1MEG A;  3S3Q A;  2YJ2 A;  9PAP A;  1QOL A;  3ERV A;  1PCI A;  3LXS A;  4I04 A;  4N79 A;  2JQF R;  1AU0 A;  2R9F A;  1DF0 A;  5F02 A;  4W4U A;  1M6D A;  1PBH A;  3WXE A;  4YVA A;  3PBH A;  3TNX A;  4OEM A;  2JQG R;  4P6G A;  4Q8H A;  2DJF B;  3HHI A;  4OEL A;  3N3K A;  3V6E A;  2AUX A;  3I06 A;  4PP1 A;  2FQ9 A;  2YJB A;  3OIS A;  3H8C A;  4YYV A;  1JQP A;  1ZCM A;  1YK8 A;  1GX3 A;  3KKU A;  1PPN A;  1YT7 A;  3IHP A;  4QRV A;  1PIP A;  3KFQ A;  2Y5B A;  1KXR A;  1CSB B;  2XU5 A;  3ZUA A;  2DCC A;  3CH2 X;  3H8B A;  5CVM A;  4C5P A;  4YYR A;  1F2A A;  2E03 A;  4QBB A;  1AEC A;  2FUD A;  3IEJ A;  1XKG A;  1YVB A;  2CIO A;  1ZIV A;  1Y4H A;  2HH5 A;  2P7U A;  2DCA A;  3H6S A;  3BOW A;  1S4V A;  2FRA A;  2HHN A;  1F29 A;  2YJ8 A;  4MSX A;  4QRX A;  1DEU A;  4HWY A;  1U5I A;  3KSE A;  4BGF A;  4N8W A;  3WXG A;  2FRQ A;  2R9M A;  2G8J A;  1ME4 A;  1MEM A;  2GHU A;  1CQD A;  3D6S A;  1SNK A;  3P5V A;  5JH3 A;  3K8U A;  2ARY A;  2E02 A;  2NQI A;  3I3T A;  1ME3 A;  3IV2 A;  2FTD A;  3QSD A;  3H89 A;  2E00 A;  2PRE A;  1U9X A;  3OF8 A;  4PP2 E;  2F1G A;  2BSZ A;  1CS8 A;  4KLB A;  2PNS A;  4CDF B;  5EGW A;  2B1M A;  3IOQ A;  1W6F A;  1IWD A;  1X9Y A;  1MS6 A;  2E01 A;  2AUZ A;  4G54 A;  1NLJ A;  1TL9 A;  1KFX L;  1BGO A;  2HXZ A;  2DZY A;  2BDZ A;  1AIM A;  1ATK A;  3B79 A;  3O0U A;  3MHS A;  1NQC A;  5CVN B;  1U9Q X;  3S3R A;  3IUT A;  2R9C A;  2P86 A;  2DCB A;  4GUZ A;  4FK5 A;  1VSN A;  1FH0 A;  1TLO A;  1Y08 A;  1AU2 A;  4YYW A;  2H7J A;  2R9O A;  1PXV A;  3BCN A;  2DC8 A;  3E1Z B;  2XU1 A;  4QRG A;  3AI8 A;  3OVX A;  4YYQ A;  2VFC A;  1GLO A;  2AYO A;  7PCK A;  4B55 A;  1W5R A;  2DCD A;  2O6X A;  1U9W A;  2DC7 A;  4FIP A;  5PAD A;  3F75 A;  3HD3 A;  4YYU A;  4BS5 A;  2FYE A;  4CDE B;  4QH6 A;  5K16 A;  3U8E A;  4FJC A;  3OVZ A;  3BC3 A;  3CBK A;  4NV7 A;  1VJV A;  5JA7 A;  1ICF A;  3DF0 A;  4CDD B;  1YK7 A;  5EF4 A;  1CVZ A;  8PCH A;  3LTW A;  4AXM A;  1GMY A;  4WA6 A;  1AYV A;  1F2B A;  5CHV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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