1CS8A

Crystal structure of procathepsin l
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
316
structure length
315
Chain Sequence
SLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDAGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment.
pubmed rcsb
molecule keywords HUMAN PROCATHEPSIN L
molecule tags Hydrolase
source organism Homo sapiens
total genus 63
structure length 315
sequence length 316
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 1999-08-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
A PF08246 Inhibitor_I29 Cathepsin propeptide inhibitor domain (I29)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1cs8A00
3KFQA 4FIPA 4QRVA 4BQVA 2E03A 3F5VA 1EF7A 1BY8A 4FJCA 1PBHA 1KXRA 1EWPA 1STFE 5FPWA 3IEJA 4I05A 2AYNA 1CTEA 2PADA 1NB5A 1YT7A 4MZSA 3O0UA 4I07A 1DEUA 2ARYA 1AYWA 1M6DA 2BDZA 5EF4A 2VHSA 4BS5A 4YYSA 1CQDA 4CZWA 1NQCA 4Q8GA 1TL9A 4OEMA 1MEMA 2H7JA 4N8WA 3RVXA 3DF0A 4ZUXU 3V6EA 2ACTA 2PREA 2NQGA 3HWNA 2NQIA 1QXPA 3QT4A 2YJ8A 3H7DA 1AU3A 5A24A 2F1GA 2ATOA 4CDDB 3I3TA 3IOQA 4FK5A 1NLJA 4PADA 3RVVA 3E1ZB 1PADA 4DMYA 3K24A 1Y08A 2FTDA 4KLBA 1CJLA 2P86A 2DCCA 4BSQA 1GCBA 2HH5A 1F2AA 1U9QX 1JQPA 3PDFA 1PXVA 2YJ2A 4CDFB 1BP4A 1VJVA 3OVZA 3BPFA 2G8EA 3PBHA 2AU1A 1TU6A 2P0RA 1PPOA 4XUIA 2YJCA 3IUTA 1YK7A 1ZIVA 4BPVA 2FRQA 2FO5A 2G7YA 2Y5BA 3NHEA 7PCKA 9PAPA 1U9VA 5F02A 1QDQA 3H8CA 4QH6A 3IV2A 2YJBA 4YVAA 3H6SA 2BDLA 3ERVA 3PNRA 3BC3A 3N4CA 2DC8A 3AI8A 3F75A 1QMYA 1AU2A 4MZOA 4AXLA 3KX1A 3BPMA 3KW9A 2DCAA 1DF0A 1YALA 2OULA 2R9OA 2DC9A 3PW3A 2CIOA 2XU1A 4N4ZA 1MIRA 1YVBA 1Q6KA 1AU4A 2GHUA 4MSXA 1A6RA 2AVWA 1THEA 2HXZA 1AU0A 3GCBA 3ZUAA 1AIMA 1SP4B 4AXMA 5JH3A 2R6NA 1CB5A 8PCHA 3M99A 3LFYA 3P5XA 4Q8HA 2R9FA 4PP2E 1F29A 3K9MA 1KFXL 3H8BA 2OP3A 1U9WA 3BCNA 1BQIA 4CDEB 2YJ9A 1AYUA 1NB3A 5CVNB 1TLOA 2O6XA 5PADA 3WXGA 4BS6A 1PE6A 1O0EA 3B79A 5CHVA 2CB5A 3TNXA 4X6JA 1PIPA 3D6SA 1EWMA 2AUXA 4I04A 5JA7A 4PI3A 1EWLA 4QRXA 3N3GA 3IMAA 2F7DA 2DZYA 5EGWA 1ICFA 1CVZA 1ME4A 4CDCB 4OELA 2G8JA 1PPNA 1EWOA 3KWBX 3P5UA 1ITOA 3KKUA 1AYVA 2NQDB 3CBKA 2E02A 1QOLA 2DC6A 1U9XA 3WXFA 1KHPA 4G54A 1F2BA 1MDWA 4N79A 4YYUA 2DJFB 3S3RA 3P5WA 1SNKA 2HHNA 3C9EA 2VHFA 4XR7A 2DCDA 5K16A 3CH3X 3HHAA 3OVXA 3O1GA 1PCIA 3N3KA 3HD3A 3H89A 1CSBB 1HUCB 3P5VA 4RY2A 2XU5A 4YYQA 3S3QA 1FH0A 2DCBA 1KHQA 1CS8A 3OF9A 2B1NA 2G6DA 4QBBA 5CHTA 3LXSA 1Y4HA 4W4UA 4P6GA 3MHSA 2JQFR 1X9YA 5CVOB 2JQGR 2PBHA 1YK8A 4W5CA 2DZZA 3V6CA 4PP1A 4X6IA 2XU3A 3MHHA 3BOWA 2PNSA 2C0YA 2GFOA 2R9NA 3U8EA 3OISA 2B1MA 3MORA 4X6HA 1S4VA 4YYVA 2P7UA 3BWKA 2E01A 2FQ9A 1U5IA 2WBFX 2OZ2A 1NPZA 4YV8A 1XKGA 3WXEA 3HHIA 1CV8A 1GMYA 3USVA 2DC7A 2AS8A 1POPA 2Y6EA 2AIMA 1F2CA 5J94A 1VSNA 2R9MA 4W5BA 4HWYA 1NL6A 3KSEA 1K3BB 4K7CA 3IHPA 4DMXA 2XU4A 3QSDA 1BGOA 1IWDA 3CH2X 2HD5A 3MTNA 2AUZA 2FT2A 4QRGA 1MEGA 4YYWA 1GECE 2FYEA 2NQAA 2AYOA 3I06A 4P6EA 4YYRA 1GLOA 2DJGB 2FUDA 3QJ3A 1ATKA 2IBIA 1MS6A 1PPPA 3KWZA 2E00A 1AECA 3OF8A 2FRAA 1KFUL 1MHWA 1ME3A 3RVWA 3CBJA 5CVMA 2IPPB 2R9CA 6PADA 1ZCMA 3K8UA 1PPDA 1CPJA 4WA6A
chains in the Genus database with same CATH superfamily
3KFQA 4FIPA 4QRVA 3B21A 4BQVA 2E03A 3F5VA 1EF7A 1BY8A 4FJCA 1PBHA 1KXRA 2BU3A 2JRIA 1EWPA 4M0WA 1STFE 5FPWA 1DKIA 3IEJA 4I05A 4OVZB 2AYNA 1CTEA 2PADA 1NB5A 1YT7A 4MZSA 3O0UA 4I07A 1DEUA 2ARYA 1AYWA 1M6DA 2BDZA 5EF4A 2VHSA 4BS5A 4YYSA 1CQDA 4D8IA 3OQCA 4CZWA 1NQCA 3MJ5A 3PHUA 4Q8GA 4MM3B 1TL9A 4OEMA 2BTWB 1MEMA 2H7JA 4N8WA 3RVXA 2Z84A 3DF0A 4ZUXU 3V6EA 2ACTA 2PREA 5JZEA 2NQGA 3HWNA 2NQIA 1QXPA 3QT4A 2UZJA 2YJ8A 3H7DA 1AU3A 2J7QC 5A24A 3TRKA 4D8BA 2F1GA 2ATOA 4RF0A 4CDDB 3I3TA 3IOQA 4FK5A 1NLJA 4PADA 4RKXA 3RVVA 3E1ZB 1PADA 4DMYA 3K24A 1Y08A 2FTDA 3MP2A 4KLBA 4WURA 1CJLA 3BB7A 2P86A 2DCCA 4BSQA 1GCBA 4BOQA 2HH5A 1F2AA 1U9QX 1JQPA 3PDFA 1PXVA 2YJ2A 4CDFB 1BP4A 3TMPA 1VJVA 3OVZA 3BPFA 2G8EA 3PBHA 2AU1A 2JTCA 1TU6A 2P0RA 1PPOA 4XUIA 2YJCA 3IUTA 1YK7A 1ZIVA 4BPVA 2FRQA 2FO5A 2G7YA 3PRMA 2DOSA 2BTWA 2Y5BA 3NHEA 4BOSA 7PCKA 9PAPA 1U9VA 5F02A 1QDQA 3H8CA 4QH6A 3IV2A 2YJBA 3E9SA 4YVAA 3H6SA 4RF1A 4IP3A 2BDLA 3ERVA 3PNRA 3BC3A 3N4CA 2DC8A 3AI8A 3F75A 1QMYA 1AU2A 4MZOA 4AXLA 3KX1A 3BPMA 3KW9A 2DCAA 1DF0A 1YALA 2OULA 2R9OA 2DC9A 3PW3A 2CIOA 3PHXA 2XU1A 4N4ZA 1MIRA 1YVBA 1Q6KA 1AU4A 2GHUA 4MSXA 1A6RA 2AVWA 1THEA 2HXZA 3IFUA 1AU0A 3GCBA 3ZUAA 1AIMA 4OW0A 3BBAA 4P16A 1SP4B 4AXMA 5JH3A 2R6NA 1CB5A 8PCHA 3M99A 3LFYA 3P5XA 4Q8HA 2R9FA 4PP2E 1F29A 3K9MA 1KFXL 3H8BA 2OP3A 1U9WA 3BCNA 1BQIA 4CDEB 2AGAA 1UKFA 5KO3A 2YJ9A 1AYUA 1NB3A 5CVNB 1TLOA 2O6XA 5PADA 3WXGA 4BS6A 1PE6A 1O0EA 3B79A 5CHVA 2CB5A 3TNXA 4X6JA 1PIPA 3D6SA 5EZSA 1EWMA 3W30A 2AUXA 4I04A 5JA7A 4PI3A 1EWLA 4QRXA 3N3GA 3IMAA 2F7DA 4ZTBA 2DZYA 5EGWA 1ICFA 1CVZA 1ME4A 4CDCB 4OELA 2G8JA 1PPNA 1EWOA 3KWBX 3P5UA 4PT5A 2HWKA 1ITOA 3KKUA 3PT2A 5EZQA 1AYVA 2NQDB 3CBKA 4BOZA 2E02A 4BOPA 1QOLA 2DC6A 1U9XA 3WXFA 1KHPA 4G54A 1F2BA 1MDWA 4N79A 4YYUA 2DJFB 3S3RA 3P5WA 1SNKA 2HHNA 3C9EA 2VHFA 5E6JA 4XR7A 2DCDA 5K16A 3CH3X 3HHAA 4BOUA 3OVXA 3C0RA 3O1GA 3ZNHA 1PCIA 3N3KA 3HD3A 3H89A 1CSBB 1HUCB 3P5VA 4RY2A 2XU5A 4YYQA 3S3QA 1FH0A 2DCBA 1KHQA 1CS8A 3OF9A 2B1NA 2G6DA 3PSEA 4QBBA 1YZBA 5CHTA 3LXSA 1Y4HA 4W4UA 4P6GA 3MHSA 2JQFR 2J7QA 1X9YA 5CVOB 4HXDB 3PRPA 2JQGR 3BY4A 2PBHA 1YK8A 4W5CA 2DZZA 3V6CA 4PP1A 3W31A 4X6IA 4RNAA 2XU3A 3MHHA 3PHWA 3BOWA 2PNSA 2C0YA 2GFOA 4MI7A 2R9NA 3U8EA 3OISA 2B1MA 3MORA 4X6HA 4REZA 4GUAA 1S4VA 4D8EA 4YYVA 2P7UA 3BWKA 2E01A 2FQ9A 1U5IA 2WBFX 2OZ2A 1NPZA 4XZXA 4YV8A 1XKGA 3WXEA 3HHIA 1CV8A 1GMYA 3USVA 2DC7A 2AS8A 1POPA 3O65A 2Y6EA 2AIMA 1F2CA 5J94A 1VSNA 3RNVA 2R9MA 4W5BA 4HWYA 1NL6A 3KSEA 1K3BB 4K7CA 4A5UA 3IHPA 4DMXA 2XU4A 3QSDA 1BGOA 1IWDA 3CH2X 2HD5A 3MTNA 2AUZA 2FT2A 4QRGA 1MEGA 4YYWA 1GECE 2FYEA 2NQAA 2AYOA 3I06A 4P6EA 4YYRA 1GLOA 2FE8A 2DJGB 2FUDA 3QJ3A 1ATKA 4IUMA 2IBIA 1MS6A 1PPPA 1PVJA 3KWZA 4R3DA 2E00A 1AECA 4OVZA 3OF8A 2FRAA 1KFUL 1MHWA 1ME3A 3RVWA 3CBJA 5CVMA 2IPPB 2R9CA 6PADA 1ZCMA 3K8UA 3MTVA 1PPDA 1CPJA 4WA6A
chains in the Genus database with same CATH topology
4NV7A 3KFQA 4FIPA 4QRVA 4BQVA 2E03A 3F5VA 1EF7A 1BY8A 4FJCA 1PBHA 1KXRA 1EWPA 1STFE 5FPWA 3IEJA 4I05A 2AYNA 1CTEA 2PADA 1NB5A 1YT7A 4MZSA 3O0UA 4I07A 1DEUA 2ARYA 1AYWA 1M6DA 2BDZA 5EF4A 2VHSA 4BS5A 4YYSA 1CQDA 4CZWA 1NQCA 4Q8GA 1TL9A 4OEMA 1MEMA 2H7JA 4N8WA 3RVXA 3DF0A 4ZUXU 3V6EA 2ACTA 2PREA 2NQGA 3HWNA 2NQIA 1QXPA 3QT4A 4BGFA 2YJ8A 3H7DA 1AU3A 5A24A 2F1GA 2ATOA 4CDDB 3I3TA 3IOQA 4FK5A 1NLJA 4PADA 3RVVA 3E1ZB 1PADA 4DMYA 3K24A 1Y08A 2FTDA 4KLBA 1CJLA 3LTWA 2P86A 2DCCA 4BSQA 1GCBA 2HH5A 1F2AA 1U9QX 1JQPA 3PDFA 1PXVA 2YJ2A 4CDFB 1BP4A 1VJVA 3OVZA 3BPFA 2G8EA 3PBHA 2AU1A 1TU6A 2P0RA 1PPOA 4XUIA 2YJCA 3IUTA 1YK7A 1ZIVA 2VFCA 4BPVA 2FRQA 2FO5A 2G7YA 2Y5BA 3NHEA 7PCKA 9PAPA 1U9VA 5F02A 1QDQA 3H8CA 4QH6A 3IV2A 2YJBA 3D9WA 4YVAA 3H6SA 2BDLA 3ERVA 3PNRA 3BC3A 3N4CA 2DC8A 3AI8A 3F75A 1QMYA 1AU2A 4MZOA 4AXLA 3KX1A 3BPMA 2VFBA 3KW9A 2DCAA 1DF0A 1YALA 2OULA 2R9OA 2DC9A 3PW3A 2CIOA 2XU1A 4N4ZA 1MIRA 1YVBA 1Q6KA 1AU4A 2GHUA 4MSXA 1A6RA 2AVWA 1THEA 2HXZA 1AU0A 3GCBA 3ZUAA 1AIMA 1SP4B 4AXMA 5JH3A 2R6NA 1CB5A 8PCHA 3M99A 3LFYA 3P5XA 4Q8HA 2R9FA 4PP2E 1F29A 3K9MA 1KFXL 3H8BA 2OP3A 1U9WA 3BCNA 1BQIA 4CDEB 2YJ9A 1AYUA 1NB3A 5CVNB 1TLOA 2O6XA 5PADA 3WXGA 4BS6A 1PE6A 1O0EA 3B79A 5CHVA 2CB5A 3TNXA 4X6JA 1PIPA 3D6SA 1EWMA 1W5RA 2AUXA 4I04A 5JA7A 4PI3A 1EWLA 4QRXA 3N3GA 3IMAA 2F7DA 2DZYA 5EGWA 1ICFA 1CVZA 1ME4A 4CDCB 4OELA 2G8JA 1PPNA 1EWOA 3KWBX 3P5UA 1ITOA 3KKUA 1AYVA 2NQDB 3CBKA 2E02A 1QOLA 2DC6A 1U9XA 3WXFA 1KHPA 4G54A 1F2BA 4GUZA 1MDWA 4N79A 4YYUA 2DJFB 3S3RA 3P5WA 1SNKA 2HHNA 3C9EA 2VHFA 4XR7A 2DCDA 5K16A 3CH3X 4NV8A 3HHAA 3OVXA 3O1GA 1PCIA 3N3KA 3HD3A 3H89A 1CSBB 1HUCB 1E2TA 3P5VA 4RY2A 2XU5A 4YYQA 3S3QA 1FH0A 2DCBA 1KHQA 1CS8A 3OF9A 2B1NA 2G6DA 4QBBA 5CHTA 3LXSA 1Y4HA 4W4UA 4P6GA 3MHSA 1W6FA 2JQFR 1X9YA 5CVOB 2JQGR 1W4TA 2PBHA 1YK8A 4W5CA 2DZZA 3V6CA 4C5PA 4PP1A 4X6IA 2XU3A 3MHHA 3BOWA 2PNSA 2C0YA 2GFOA 2R9NA 3U8EA 3OISA 2B1MA 3MORA 4X6HA 1S4VA 4YYVA 2P7UA 3BWKA 4B55A 2E01A 2FQ9A 1U5IA 2WBFX 1GX3A 2OZ2A 1NPZA 4YV8A 1XKGA 3WXEA 3HHIA 1CV8A 1GMYA 3USVA 2DC7A 2AS8A 1POPA 2Y6EA 2AIMA 1F2CA 5J94A 1VSNA 2R9MA 4W5BA 4HWYA 1NL6A 3KSEA 1K3BB 4K7CA 3IHPA 4DMXA 2XU4A 3QSDA 1BGOA 1IWDA 3CH2X 2HD5A 3MTNA 2AUZA 2FT2A 4QRGA 1MEGA 4YYWA 1GECE 2FYEA 2NQAA 2AYOA 3I06A 4P6EA 4YYRA 1GLOA 2DJGB 2FUDA 3QJ3A 1ATKA 2BSZA 2IBIA 1MS6A 1PPPA 3KWZA 2E00A 1AECA 3OF8A 2FRAA 1KFUL 1MHWA 1ME3A 3RVWA 3CBJA 5CVMA 2IPPB 2R9CA 6PADA 1ZCMA 3K8UA 1PPDA 1CPJA 4WA6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KFQ A;  4FIP A;  4QRV A;  4BQV A;  2E03 A;  3F5V A;  1EF7 A;  1BY8 A;  4FJC A;  1PBH A;  1KXR A;  1EWP A;  1STF E;  5FPW A;  3IEJ A;  4I05 A;  2AYN A;  1CTE A;  2PAD A;  1NB5 A;  1YT7 A;  4MZS A;  3O0U A;  4I07 A;  1DEU A;  2ARY A;  1AYW A;  1M6D A;  2BDZ A;  5EF4 A;  2VHS A;  4BS5 A;  4YYS A;  1CQD A;  4CZW A;  1NQC A;  4Q8G A;  1TL9 A;  4OEM A;  1MEM A;  2H7J A;  4N8W A;  3RVX A;  3DF0 A;  4ZUX U;  3V6E A;  2ACT A;  2PRE A;  2NQG A;  3HWN A;  2NQI A;  1QXP A;  3QT4 A;  2YJ8 A;  3H7D A;  1AU3 A;  5A24 A;  2F1G A;  2ATO A;  4CDD B;  3I3T A;  3IOQ A;  4FK5 A;  1NLJ A;  4PAD A;  3RVV A;  3E1Z B;  1PAD A;  4DMY A;  3K24 A;  1Y08 A;  2FTD A;  4KLB A;  1CJL A;  2P86 A;  2DCC A;  4BSQ A;  1GCB A;  2HH5 A;  1F2A A;  1U9Q X;  1JQP A;  3PDF A;  1PXV A;  2YJ2 A;  4CDF B;  1BP4 A;  1VJV A;  3OVZ A;  3BPF A;  2G8E A;  3PBH A;  2AU1 A;  1TU6 A;  2P0R A;  1PPO A;  4XUI A;  2YJC A;  3IUT A;  1YK7 A;  1ZIV A;  4BPV A;  2FRQ A;  2FO5 A;  2G7Y A;  2Y5B A;  3NHE A;  7PCK A;  9PAP A;  1U9V A;  5F02 A;  1QDQ A;  3H8C A;  4QH6 A;  3IV2 A;  2YJB A;  4YVA A;  3H6S A;  2BDL A;  3ERV A;  3PNR A;  3BC3 A;  3N4C A;  2DC8 A;  3AI8 A;  3F75 A;  1QMY A;  1AU2 A;  4MZO A;  4AXL A;  3KX1 A;  3BPM A;  3KW9 A;  2DCA A;  1DF0 A;  1YAL A;  2OUL A;  2R9O A;  2DC9 A;  3PW3 A;  2CIO A;  2XU1 A;  4N4Z A;  1MIR A;  1YVB A;  1Q6K A;  1AU4 A;  2GHU A;  4MSX A;  1A6R A;  2AVW A;  1THE A;  2HXZ A;  1AU0 A;  3GCB A;  3ZUA A;  1AIM A;  1SP4 B;  4AXM A;  5JH3 A;  2R6N A;  1CB5 A;  8PCH A;  3M99 A;  3LFY A;  3P5X A;  4Q8H A;  2R9F A;  4PP2 E;  1F29 A;  3K9M A;  1KFX L;  3H8B A;  2OP3 A;  1U9W A;  3BCN A;  1BQI A;  4CDE B;  2YJ9 A;  1AYU A;  1NB3 A;  5CVN B;  1TLO A;  2O6X A;  5PAD A;  3WXG A;  4BS6 A;  1PE6 A;  1O0E A;  3B79 A;  5CHV A;  2CB5 A;  3TNX A;  4X6J A;  1PIP A;  3D6S A;  1EWM A;  2AUX A;  4I04 A;  5JA7 A;  4PI3 A;  1EWL A;  4QRX A;  3N3G A;  3IMA A;  2F7D A;  2DZY A;  5EGW A;  1ICF A;  1CVZ A;  1ME4 A;  4CDC B;  4OEL A;  2G8J A;  1PPN A;  1EWO A;  3KWB X;  3P5U A;  1ITO A;  3KKU A;  1AYV A;  2NQD B;  3CBK A;  2E02 A;  1QOL A;  2DC6 A;  1U9X A;  3WXF A;  1KHP A;  4G54 A;  1F2B A;  1MDW A;  4N79 A;  4YYU A;  2DJF B;  3S3R A;  3P5W A;  1SNK A;  2HHN A;  3C9E A;  2VHF A;  4XR7 A;  2DCD A;  5K16 A;  3CH3 X;  3HHA A;  3OVX A;  3O1G A;  1PCI A;  3N3K A;  3HD3 A;  3H89 A;  1CSB B;  1HUC B;  3P5V A;  4RY2 A;  2XU5 A;  4YYQ A;  3S3Q A;  1FH0 A;  2DCB A;  1KHQ A;  1CS8 A;  3OF9 A;  2B1N A;  2G6D A;  4QBB A;  5CHT A;  3LXS A;  1Y4H A;  4W4U A;  4P6G A;  3MHS A;  2JQF R;  1X9Y A;  5CVO B;  2JQG R;  2PBH A;  1YK8 A;  4W5C A;  2DZZ A;  3V6C A;  4PP1 A;  4X6I A;  2XU3 A;  3MHH A;  3BOW A;  2PNS A;  2C0Y A;  2GFO A;  2R9N A;  3U8E A;  3OIS A;  2B1M A;  3MOR A;  4X6H A;  1S4V A;  4YYV A;  2P7U A;  3BWK A;  2E01 A;  2FQ9 A;  1U5I A;  2WBF X;  2OZ2 A;  1NPZ A;  4YV8 A;  1XKG A;  3WXE A;  3HHI A;  1CV8 A;  1GMY A;  3USV A;  2DC7 A;  2AS8 A;  1POP A;  2Y6E A;  2AIM A;  1F2C A;  5J94 A;  1VSN A;  2R9M A;  4W5B A;  4HWY A;  1NL6 A;  3KSE A;  1K3B B;  4K7C A;  3IHP A;  4DMX A;  2XU4 A;  3QSD A;  1BGO A;  1IWD A;  3CH2 X;  2HD5 A;  3MTN A;  2AUZ A;  2FT2 A;  4QRG A;  1MEG A;  4YYW A;  1GEC E;  2FYE A;  2NQA A;  2AYO A;  3I06 A;  4P6E A;  4YYR A;  1GLO A;  2DJG B;  2FUD A;  3QJ3 A;  1ATK A;  2IBI A;  1MS6 A;  1PPP A;  3KWZ A;  2E00 A;  1AEC A;  3OF8 A;  2FRA A;  1KFU L;  1MHW A;  1ME3 A;  3RVW A;  3CBJ A;  5CVM A;  2IPP B;  2R9C A;  6PAD A;  1ZCM A;  3K8U A;  1PPD A;  1CPJ A;  4WA6 A; 
#chains in the Genus database with same CATH topology
 3KFQ A;  4FIP A;  4QRV A;  3B21 A;  4BQV A;  2E03 A;  3F5V A;  1EF7 A;  1BY8 A;  4FJC A;  1PBH A;  1KXR A;  2BU3 A;  2JRI A;  1EWP A;  4M0W A;  1STF E;  5FPW A;  1DKI A;  3IEJ A;  4I05 A;  4OVZ B;  2AYN A;  1CTE A;  2PAD A;  1NB5 A;  1YT7 A;  4MZS A;  3O0U A;  4I07 A;  1DEU A;  2ARY A;  1AYW A;  1M6D A;  2BDZ A;  5EF4 A;  2VHS A;  4BS5 A;  4YYS A;  1CQD A;  4D8I A;  3OQC A;  4CZW A;  1NQC A;  3MJ5 A;  3PHU A;  4Q8G A;  4MM3 B;  1TL9 A;  4OEM A;  2BTW B;  1MEM A;  2H7J A;  4N8W A;  3RVX A;  2Z84 A;  3DF0 A;  4ZUX U;  3V6E A;  2ACT A;  2PRE A;  5JZE A;  2NQG A;  3HWN A;  2NQI A;  1QXP A;  3QT4 A;  2UZJ A;  2YJ8 A;  3H7D A;  1AU3 A;  2J7Q C;  5A24 A;  3TRK A;  4D8B A;  2F1G A;  2ATO A;  4RF0 A;  4CDD B;  3I3T A;  3IOQ A;  4FK5 A;  1NLJ A;  4PAD A;  4RKX A;  3RVV A;  3E1Z B;  1PAD A;  4DMY A;  3K24 A;  1Y08 A;  2FTD A;  3MP2 A;  4KLB A;  4WUR A;  1CJL A;  3BB7 A;  2P86 A;  2DCC A;  4BSQ A;  1GCB A;  4BOQ A;  2HH5 A;  1F2A A;  1U9Q X;  1JQP A;  3PDF A;  1PXV A;  2YJ2 A;  4CDF B;  1BP4 A;  3TMP A;  1VJV A;  3OVZ A;  3BPF A;  2G8E A;  3PBH A;  2AU1 A;  2JTC A;  1TU6 A;  2P0R A;  1PPO A;  4XUI A;  2YJC A;  3IUT A;  1YK7 A;  1ZIV A;  4BPV A;  2FRQ A;  2FO5 A;  2G7Y A;  3PRM A;  2DOS A;  2BTW A;  2Y5B A;  3NHE A;  4BOS A;  7PCK A;  9PAP A;  1U9V A;  5F02 A;  1QDQ A;  3H8C A;  4QH6 A;  3IV2 A;  2YJB A;  3E9S A;  4YVA A;  3H6S A;  4RF1 A;  4IP3 A;  2BDL A;  3ERV A;  3PNR A;  3BC3 A;  3N4C A;  2DC8 A;  3AI8 A;  3F75 A;  1QMY A;  1AU2 A;  4MZO A;  4AXL A;  3KX1 A;  3BPM A;  3KW9 A;  2DCA A;  1DF0 A;  1YAL A;  2OUL A;  2R9O A;  2DC9 A;  3PW3 A;  2CIO A;  3PHX A;  2XU1 A;  4N4Z A;  1MIR A;  1YVB A;  1Q6K A;  1AU4 A;  2GHU A;  4MSX A;  1A6R A;  2AVW A;  1THE A;  2HXZ A;  3IFU A;  1AU0 A;  3GCB A;  3ZUA A;  1AIM A;  4OW0 A;  3BBA A;  4P16 A;  1SP4 B;  4AXM A;  5JH3 A;  2R6N A;  1CB5 A;  8PCH A;  3M99 A;  3LFY A;  3P5X A;  4Q8H A;  2R9F A;  4PP2 E;  1F29 A;  3K9M A;  1KFX L;  3H8B A;  2OP3 A;  1U9W A;  3BCN A;  1BQI A;  4CDE B;  2AGA A;  1UKF A;  5KO3 A;  2YJ9 A;  1AYU A;  1NB3 A;  5CVN B;  1TLO A;  2O6X A;  5PAD A;  3WXG A;  4BS6 A;  1PE6 A;  1O0E A;  3B79 A;  5CHV A;  2CB5 A;  3TNX A;  4X6J A;  1PIP A;  3D6S A;  5EZS A;  1EWM A;  3W30 A;  2AUX A;  4I04 A;  5JA7 A;  4PI3 A;  1EWL A;  4QRX A;  3N3G A;  3IMA A;  2F7D A;  4ZTB A;  2DZY A;  5EGW A;  1ICF A;  1CVZ A;  1ME4 A;  4CDC B;  4OEL A;  2G8J A;  1PPN A;  1EWO A;  3KWB X;  3P5U A;  4PT5 A;  2HWK A;  1ITO A;  3KKU A;  3PT2 A;  5EZQ A;  1AYV A;  2NQD B;  3CBK A;  4BOZ A;  2E02 A;  4BOP A;  1QOL A;  2DC6 A;  1U9X A;  3WXF A;  1KHP A;  4G54 A;  1F2B A;  1MDW A;  4N79 A;  4YYU A;  2DJF B;  3S3R A;  3P5W A;  1SNK A;  2HHN A;  3C9E A;  2VHF A;  5E6J A;  4XR7 A;  2DCD A;  5K16 A;  3CH3 X;  3HHA A;  4BOU A;  3OVX A;  3C0R A;  3O1G A;  3ZNH A;  1PCI A;  3N3K A;  3HD3 A;  3H89 A;  1CSB B;  1HUC B;  3P5V A;  4RY2 A;  2XU5 A;  4YYQ A;  3S3Q A;  1FH0 A;  2DCB A;  1KHQ A;  1CS8 A;  3OF9 A;  2B1N A;  2G6D A;  3PSE A;  4QBB A;  1YZB A;  5CHT A;  3LXS A;  1Y4H A;  4W4U A;  4P6G A;  3MHS A;  2JQF R;  2J7Q A;  1X9Y A;  5CVO B;  4HXD B;  3PRP A;  2JQG R;  3BY4 A;  2PBH A;  1YK8 A;  4W5C A;  2DZZ A;  3V6C A;  4PP1 A;  3W31 A;  4X6I A;  4RNA A;  2XU3 A;  3MHH A;  3PHW A;  3BOW A;  2PNS A;  2C0Y A;  2GFO A;  4MI7 A;  2R9N A;  3U8E A;  3OIS A;  2B1M A;  3MOR A;  4X6H A;  4REZ A;  4GUA A;  1S4V A;  4D8E A;  4YYV A;  2P7U A;  3BWK A;  2E01 A;  2FQ9 A;  1U5I A;  2WBF X;  2OZ2 A;  1NPZ A;  4XZX A;  4YV8 A;  1XKG A;  3WXE A;  3HHI A;  1CV8 A;  1GMY A;  3USV A;  2DC7 A;  2AS8 A;  1POP A;  3O65 A;  2Y6E A;  2AIM A;  1F2C A;  5J94 A;  1VSN A;  3RNV A;  2R9M A;  4W5B A;  4HWY A;  1NL6 A;  3KSE A;  1K3B B;  4K7C A;  4A5U A;  3IHP A;  4DMX A;  2XU4 A;  3QSD A;  1BGO A;  1IWD A;  3CH2 X;  2HD5 A;  3MTN A;  2AUZ A;  2FT2 A;  4QRG A;  1MEG A;  4YYW A;  1GEC E;  2FYE A;  2NQA A;  2AYO A;  3I06 A;  4P6E A;  4YYR A;  1GLO A;  2FE8 A;  2DJG B;  2FUD A;  3QJ3 A;  1ATK A;  4IUM A;  2IBI A;  1MS6 A;  1PPP A;  1PVJ A;  3KWZ A;  4R3D A;  2E00 A;  1AEC A;  4OVZ A;  3OF8 A;  2FRA A;  1KFU L;  1MHW A;  1ME3 A;  3RVW A;  3CBJ A;  5CVM A;  2IPP B;  2R9C A;  6PAD A;  1ZCM A;  3K8U A;  3MTV A;  1PPD A;  1CPJ A;  4WA6 A; 
#chains in the Genus database with same CATH homology
 4NV7 A;  3KFQ A;  4FIP A;  4QRV A;  4BQV A;  2E03 A;  3F5V A;  1EF7 A;  1BY8 A;  4FJC A;  1PBH A;  1KXR A;  1EWP A;  1STF E;  5FPW A;  3IEJ A;  4I05 A;  2AYN A;  1CTE A;  2PAD A;  1NB5 A;  1YT7 A;  4MZS A;  3O0U A;  4I07 A;  1DEU A;  2ARY A;  1AYW A;  1M6D A;  2BDZ A;  5EF4 A;  2VHS A;  4BS5 A;  4YYS A;  1CQD A;  4CZW A;  1NQC A;  4Q8G A;  1TL9 A;  4OEM A;  1MEM A;  2H7J A;  4N8W A;  3RVX A;  3DF0 A;  4ZUX U;  3V6E A;  2ACT A;  2PRE A;  2NQG A;  3HWN A;  2NQI A;  1QXP A;  3QT4 A;  4BGF A;  2YJ8 A;  3H7D A;  1AU3 A;  5A24 A;  2F1G A;  2ATO A;  4CDD B;  3I3T A;  3IOQ A;  4FK5 A;  1NLJ A;  4PAD A;  3RVV A;  3E1Z B;  1PAD A;  4DMY A;  3K24 A;  1Y08 A;  2FTD A;  4KLB A;  1CJL A;  3LTW A;  2P86 A;  2DCC A;  4BSQ A;  1GCB A;  2HH5 A;  1F2A A;  1U9Q X;  1JQP A;  3PDF A;  1PXV A;  2YJ2 A;  4CDF B;  1BP4 A;  1VJV A;  3OVZ A;  3BPF A;  2G8E A;  3PBH A;  2AU1 A;  1TU6 A;  2P0R A;  1PPO A;  4XUI A;  2YJC A;  3IUT A;  1YK7 A;  1ZIV A;  2VFC A;  4BPV A;  2FRQ A;  2FO5 A;  2G7Y A;  2Y5B A;  3NHE A;  7PCK A;  9PAP A;  1U9V A;  5F02 A;  1QDQ A;  3H8C A;  4QH6 A;  3IV2 A;  2YJB A;  3D9W A;  4YVA A;  3H6S A;  2BDL A;  3ERV A;  3PNR A;  3BC3 A;  3N4C A;  2DC8 A;  3AI8 A;  3F75 A;  1QMY A;  1AU2 A;  4MZO A;  4AXL A;  3KX1 A;  3BPM A;  2VFB A;  3KW9 A;  2DCA A;  1DF0 A;  1YAL A;  2OUL A;  2R9O A;  2DC9 A;  3PW3 A;  2CIO A;  2XU1 A;  4N4Z A;  1MIR A;  1YVB A;  1Q6K A;  1AU4 A;  2GHU A;  4MSX A;  1A6R A;  2AVW A;  1THE A;  2HXZ A;  1AU0 A;  3GCB A;  3ZUA A;  1AIM A;  1SP4 B;  4AXM A;  5JH3 A;  2R6N A;  1CB5 A;  8PCH A;  3M99 A;  3LFY A;  3P5X A;  4Q8H A;  2R9F A;  4PP2 E;  1F29 A;  3K9M A;  1KFX L;  3H8B A;  2OP3 A;  1U9W A;  3BCN A;  1BQI A;  4CDE B;  2YJ9 A;  1AYU A;  1NB3 A;  5CVN B;  1TLO A;  2O6X A;  5PAD A;  3WXG A;  4BS6 A;  1PE6 A;  1O0E A;  3B79 A;  5CHV A;  2CB5 A;  3TNX A;  4X6J A;  1PIP A;  3D6S A;  1EWM A;  1W5R A;  2AUX A;  4I04 A;  5JA7 A;  4PI3 A;  1EWL A;  4QRX A;  3N3G A;  3IMA A;  2F7D A;  2DZY A;  5EGW A;  1ICF A;  1CVZ A;  1ME4 A;  4CDC B;  4OEL A;  2G8J A;  1PPN A;  1EWO A;  3KWB X;  3P5U A;  1ITO A;  3KKU A;  1AYV A;  2NQD B;  3CBK A;  2E02 A;  1QOL A;  2DC6 A;  1U9X A;  3WXF A;  1KHP A;  4G54 A;  1F2B A;  4GUZ A;  1MDW A;  4N79 A;  4YYU A;  2DJF B;  3S3R A;  3P5W A;  1SNK A;  2HHN A;  3C9E A;  2VHF A;  4XR7 A;  2DCD A;  5K16 A;  3CH3 X;  4NV8 A;  3HHA A;  3OVX A;  3O1G A;  1PCI A;  3N3K A;  3HD3 A;  3H89 A;  1CSB B;  1HUC B;  1E2T A;  3P5V A;  4RY2 A;  2XU5 A;  4YYQ A;  3S3Q A;  1FH0 A;  2DCB A;  1KHQ A;  1CS8 A;  3OF9 A;  2B1N A;  2G6D A;  4QBB A;  5CHT A;  3LXS A;  1Y4H A;  4W4U A;  4P6G A;  3MHS A;  1W6F A;  2JQF R;  1X9Y A;  5CVO B;  2JQG R;  1W4T A;  2PBH A;  1YK8 A;  4W5C A;  2DZZ A;  3V6C A;  4C5P A;  4PP1 A;  4X6I A;  2XU3 A;  3MHH A;  3BOW A;  2PNS A;  2C0Y A;  2GFO A;  2R9N A;  3U8E A;  3OIS A;  2B1M A;  3MOR A;  4X6H A;  1S4V A;  4YYV A;  2P7U A;  3BWK A;  4B55 A;  2E01 A;  2FQ9 A;  1U5I A;  2WBF X;  1GX3 A;  2OZ2 A;  1NPZ A;  4YV8 A;  1XKG A;  3WXE A;  3HHI A;  1CV8 A;  1GMY A;  3USV A;  2DC7 A;  2AS8 A;  1POP A;  2Y6E A;  2AIM A;  1F2C A;  5J94 A;  1VSN A;  2R9M A;  4W5B A;  4HWY A;  1NL6 A;  3KSE A;  1K3B B;  4K7C A;  3IHP A;  4DMX A;  2XU4 A;  3QSD A;  1BGO A;  1IWD A;  3CH2 X;  2HD5 A;  3MTN A;  2AUZ A;  2FT2 A;  4QRG A;  1MEG A;  4YYW A;  1GEC E;  2FYE A;  2NQA A;  2AYO A;  3I06 A;  4P6E A;  4YYR A;  1GLO A;  2DJG B;  2FUD A;  3QJ3 A;  1ATK A;  2BSZ A;  2IBI A;  1MS6 A;  1PPP A;  3KWZ A;  2E00 A;  1AEC A;  3OF8 A;  2FRA A;  1KFU L;  1MHW A;  1ME3 A;  3RVW A;  3CBJ A;  5CVM A;  2IPP B;  2R9C A;  6PAD A;  1ZCM A;  3K8U A;  1PPD A;  1CPJ A;  4WA6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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