4AXLA

Human cathepsin l apo form with zn
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
220
structure length
220
Chain Sequence
APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords CATHEPSIN L1
publication title Optimization of Triazine Nitriles as Rhodesain Inhibitors: Structure-Activity Relationships, Bioisosteric Imidazopyridine Nitriles, and X-Ray Crystal Structure Analysis with Human Cathepsin L
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 68
structure length 220
sequence length 220
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2012-06-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 4axlA00
4QRGA 2OULA 1SNKA 2GFOA 3MHHA 2XU5A 2FTDA 2PREA 3KW9A 4CDEB 4X6HA 3PDFA 3AI8A 1GECE 1O0EA 3OVZA 1AU2A 2JQGR 1S4VA 2PNSA 2ACTA 1GLOA 3CH2X 1NLJA 2BDZA 3H7DA 3QSDA 2G8JA 4CDDB 3N3GA 3IMAA 1KFXL 2DC7A 3P5WA 4YV8A 1MEGA 4QH6A 2R9MA 3BOWA 2DJGB 5JH3A 4AXMA 2YJ9A 2P0RA 1BQIA 2FO5A 3KWZA 4N8WA 3H8BA 1PPPA 2DCDA 2PBHA 1STFE 2P7UA 3MTNA 4CZWA 1AYWA 1EWLA 1YK8A 2VHSA 3ERVA 3OF9A 1AIMA 1KHPA 3D6SA 4YYQA 3BCNA 3QT4A 1YT7A 2CIOA 5FPWA 3ZUAA 4MZOA 4RY2A 1EWMA 1ZIVA 1KHQA 1AYUA 1MEMA 2AUZA 2NQDB 3BPFA 3K8UA 1NB5A 2AUXA 2R9OA 1FH0A 2FRQA 3P5XA 1K3BB 2XU4A 3LFYA 3P5VA 4P6GA 2E02A 2YJBA 3RVVA 2B1MA 2DC9A 3OF8A 3KFQA 1MIRA 3H89A 4BQVA 2PADA 1F2AA 3PW3A 3OVXA 3V6CA 5CHVA 2FT2A 2AYOA 4I05A 1CSBB 2AU1A 2F1GA 1ITOA 1AYVA 1F2BA 1PPOA 4FK5A 4BSQA 2DCBA 1QXPA 3CH3X 3V6EA 2IPPB 2AS8A 3KX1A 4MZSA 2G6DA 1QDQA 4HWYA 5CHTA 1F29A 1QMYA 2E00A 3H6SA 3HHIA 1KXRA 1PPDA 2NQIA 3U8EA 1NPZA 3MHSA 1CV8A 2AYNA 2Y6EA 2XU1A 3CBKA 4PADA 2ATOA 1CPJA 4YYUA 4QBBA 6PADA 2OP3A 1IWDA 2G7YA 3I3TA 1VJVA 1PBHA 1Q6KA 2FUDA 4XR7A 2NQAA 2O6XA 1KFUL 3IV2A 3BWKA 3PBHA 4X6JA 4W5BA 4N79A 1U9WA 4Q8HA 1TL9A 1U9QX 1YK7A 2DC6A 4YYVA 3E1ZB 3BC3A 4PP1A 1BY8A 4QRVA 5CVOB 3M99A 1F2CA 4X6IA 1THEA 1Y4HA 1BGOA 1NQCA 2VHFA 3GCBA 2DC8A 5K16A 1QOLA 3NHEA 2E03A 3H8CA 2H7JA 1M6DA 1A6RA 4KLBA 3USVA 5JA7A 1U5IA 2DZYA 3F75A 3CBJA 1JQPA 4CDCB 4OELA 4BS5A 5EF4A 4N4ZA 3C9EA 3WXEA 3IHPA 5A24A 1ATKA 1PXVA 2P86A 2BDLA 1TLOA 3S3RA 2YJCA 1CQDA 2FRAA 3K9MA 3WXGA 1VSNA 3IOQA 2NQGA 1U9VA 4DMYA 4YYRA 2XU3A 4AXLA 2YJ8A 1Y08A 1AU4A 4BPVA 5PADA 1POPA 4K7CA 2HXZA 3K24A 2FQ9A 1AU3A 3N3KA 2IBIA 2JQFR 4BS6A 2OZ2A 3LXSA 1ME3A 2ARYA 2DCCA 3KWBX 1U9XA 1EWOA 1CS8A 2DCAA 1YALA 4I04A 3TNXA 1EWPA 3IUTA 2Y5BA 4W5CA 3S3QA 1ZCMA 4FIPA 4PI3A 3B79A 1PPNA 1AECA 4YYSA 3O1GA 1GCBA 1EF7A 5J94A 3F5VA 1MHWA 4WA6A 3DF0A 1NL6A 3N4CA 3MORA 2AIMA 1CVZA 2AVWA 3QJ3A 2HHNA 4XUIA 4PP2E 4OEMA 1MS6A 3WXFA 2DJFB 2F7DA 2R6NA 2YJ2A 4Q8GA 2B1NA 1TU6A 4G54A 7PCKA 1PADA 3KSEA 5EGWA 1CJLA 2R9CA 4ZUXU 3O0UA 4MSXA 1ICFA 4QRXA 3BPMA 4YVAA 1X9YA 1PE6A 2G8EA 3IEJA 1DEUA 2C0YA 1CTEA 5CVMA 1HUCB 3PNRA 1MDWA 4YYWA 4W4UA 1DF0A 4CDFB 3I06A 2HH5A 4I07A 1NB3A 1PCIA 2R9NA 2HD5A 9PAPA 2FYEA 2GHUA 1AU0A 5F02A 3RVWA 4DMXA 1YVBA 3RVXA 1XKGA 2R9FA 1GMYA 3HHAA 1ME4A 3HD3A 1PIPA 4P6EA 1SP4B 8PCHA 2WBFX 3KKUA 1BP4A 2E01A 4FJCA 3OISA 2DZZA 3HWNA 2CB5A 5CVNB 3P5UA 1CB5A
chains in the Genus database with same CATH superfamily
4QRGA 2OULA 1SNKA 2HWKA 2JTCA 2GFOA 3MHHA 2XU5A 2FTDA 2PREA 1PVJA 3KW9A 4CDEB 4X6HA 3PDFA 3AI8A 1GECE 4D8EA 1O0EA 3OVZA 1AU2A 2JQGR 1S4VA 2PNSA 5E6JA 2ACTA 1GLOA 3CH2X 1NLJA 2BDZA 3H7DA 3QSDA 4BOUA 2G8JA 4CDDB 3N3GA 3IMAA 1KFXL 2DC7A 3P5WA 4YV8A 1MEGA 4QH6A 2R9MA 3BOWA 4D8BA 2DJGB 5JH3A 2JRIA 4AXMA 2YJ9A 2P0RA 1BQIA 2FO5A 3KWZA 4N8WA 3H8BA 1PPPA 2DCDA 2PBHA 1STFE 2P7UA 3MTNA 4D8IA 4CZWA 1AYWA 3W30A 1EWLA 1YK8A 2VHSA 3ERVA 3B21A 1AIMA 3OF9A 2Z84A 1KHPA 3D6SA 4YYQA 3BCNA 3QT4A 1YT7A 2CIOA 5FPWA 3ZUAA 4MZOA 4RY2A 3PRMA 1EWMA 1ZIVA 4BOSA 1KHQA 1AYUA 1MEMA 2AUZA 2NQDB 3BPFA 3K8UA 2FE8A 1NB5A 3MP2A 2AUXA 2R9OA 1FH0A 2FRQA 3P5XA 1K3BB 2XU4A 3LFYA 3P5VA 4P6GA 2E02A 2YJBA 3RVVA 2B1MA 2DC9A 3OF8A 3KFQA 1MIRA 3H89A 4BQVA 3TRKA 3TMPA 2PADA 1F2AA 3PW3A 3OVXA 3V6CA 5CHVA 3BBAA 2FT2A 2AYOA 4I05A 1CSBB 2AU1A 2F1GA 3IFUA 1ITOA 1AYVA 1F2BA 1PPOA 4FK5A 4BSQA 2DCBA 1QXPA 3CH3X 3V6EA 2IPPB 2AS8A 3KX1A 4MZSA 2G6DA 2DOSA 1QDQA 4HWYA 5CHTA 1F29A 1QMYA 2E00A 3H6SA 3HHIA 1KXRA 1PPDA 2NQIA 3U8EA 1NPZA 3MHSA 1CV8A 2AYNA 2Y6EA 4MI7A 2XU1A 3CBKA 4PADA 2ATOA 1CPJA 4YYUA 4QBBA 6PADA 1UKFA 2OP3A 1IWDA 2G7YA 3I3TA 4GUAA 1VJVA 1PBHA 1Q6KA 2FUDA 4XR7A 2NQAA 5JZEA 2O6XA 1KFUL 3IV2A 3BWKA 3PBHA 4X6JA 4W5BA 3PT2A 4N79A 1U9WA 4IP3A 4Q8HA 1TL9A 1U9QX 1YK7A 2DC6A 4YYVA 3E1ZB 3BC3A 4PP1A 3W31A 1BY8A 4QRVA 5CVOB 3M99A 1F2CA 4X6IA 1THEA 1Y4HA 1BGOA 1NQCA 2VHFA 3O65A 3GCBA 2DC8A 5K16A 1QOLA 3NHEA 2E03A 3H8CA 4PT5A 3BY4A 2H7JA 1M6DA 1A6RA 4KLBA 3USVA 3PRPA 5JA7A 1U5IA 2DZYA 4HXDB 4A5UA 3F75A 3CBJA 1JQPA 4CDCB 4OELA 4BS5A 2BU3A 5EF4A 4N4ZA 3C9EA 3WXEA 3IHPA 5A24A 5EZSA 1ATKA 1PXVA 2P86A 4XZXA 2BDLA 1TLOA 4WURA 3S3RA 2YJCA 1CQDA 2FRAA 3K9MA 3WXGA 1VSNA 3IOQA 2NQGA 2BTWB 1U9VA 4DMYA 4YYRA 2XU3A 4AXLA 2BTWA 1YZBA 2YJ8A 4RF0A 4REZA 1Y08A 4P16A 1AU4A 4BPVA 5PADA 1POPA 4K7CA 2HXZA 3K24A 4M0WA 2FQ9A 1AU3A 3N3KA 2IBIA 2JQFR 2J7QC 4BS6A 2OZ2A 3LXSA 1ME3A 2ARYA 2DCCA 3KWBX 1U9XA 1EWOA 1CS8A 4R3DA 2DCAA 1YALA 4I04A 3TNXA 3ZNHA 1EWPA 3IUTA 4BOQA 2Y5BA 4W5CA 3S3QA 1DKIA 3OQCA 3BB7A 1ZCMA 4FIPA 4PI3A 3B79A 1PPNA 1AECA 4YYSA 3O1GA 1GCBA 1EF7A 4ZTBA 5J94A 3F5VA 1MHWA 4WA6A 3DF0A 4OVZB 3N4CA 1NL6A 3MORA 4OVZA 2AIMA 4RKXA 1CVZA 3C0RA 2AVWA 3QJ3A 3PSEA 2HHNA 4RF1A 4XUIA 4PP2E 4OEMA 1MS6A 3WXFA 2DJFB 2F7DA 2R6NA 2YJ2A 4Q8GA 2B1NA 4RNAA 1TU6A 3E9SA 4G54A 7PCKA 1PADA 3KSEA 2J7QA 5EGWA 1CJLA 2R9CA 5KO3A 4ZUXU 3O0UA 4MSXA 1ICFA 4QRXA 4BOZA 3BPMA 4YVAA 1X9YA 2AGAA 1PE6A 3RNVA 2G8EA 3MTVA 3IEJA 1DEUA 2C0YA 1CTEA 5CVMA 1HUCB 3PNRA 1MDWA 4YYWA 4W4UA 1DF0A 4CDFB 3I06A 2HH5A 4I07A 1NB3A 1PCIA 2R9NA 2HD5A 9PAPA 2FYEA 3PHUA 2GHUA 1AU0A 5F02A 3RVWA 4DMXA 1YVBA 3RVXA 1XKGA 3MJ5A 2R9FA 4OW0A 3PHXA 1GMYA 3HHAA 1ME4A 3HD3A 1PIPA 4P6EA 1SP4B 8PCHA 2WBFX 3KKUA 1BP4A 2E01A 4FJCA 4MM3B 3OISA 2DZZA 3HWNA 2UZJA 2CB5A 4BOPA 4IUMA 5EZQA 5CVNB 3P5UA 3PHWA 1CB5A
chains in the Genus database with same CATH topology
4QRGA 2OULA 1SNKA 2GFOA 3MHHA 2XU5A 2FTDA 2PREA 1W4TA 3KW9A 4CDEB 4X6HA 3PDFA 3AI8A 1GECE 1O0EA 3OVZA 1AU2A 2JQGR 1S4VA 4NV8A 2PNSA 2ACTA 1GLOA 3CH2X 1NLJA 3LTWA 2BDZA 3H7DA 3QSDA 2VFCA 2G8JA 4CDDB 3N3GA 4BGFA 3IMAA 1KFXL 2DC7A 3P5WA 4YV8A 1MEGA 4QH6A 2R9MA 3BOWA 2DJGB 5JH3A 4AXMA 2YJ9A 2P0RA 1BQIA 2FO5A 3KWZA 4N8WA 3H8BA 1PPPA 2DCDA 1GX3A 2PBHA 1STFE 2P7UA 3MTNA 4CZWA 1AYWA 1EWLA 1YK8A 2VHSA 3ERVA 3OF9A 1AIMA 1KHPA 3D6SA 4YYQA 3BCNA 3QT4A 1YT7A 2CIOA 5FPWA 3ZUAA 4B55A 4MZOA 4RY2A 1EWMA 1ZIVA 1KHQA 1AYUA 1MEMA 2AUZA 2NQDB 3BPFA 3K8UA 1NB5A 2AUXA 2BSZA 2R9OA 1FH0A 2FRQA 3P5XA 1K3BB 2XU4A 3LFYA 3P5VA 4P6GA 2E02A 2YJBA 3RVVA 2B1MA 2DC9A 3OF8A 3KFQA 1MIRA 3H89A 4BQVA 2PADA 1F2AA 3PW3A 3OVXA 3V6CA 5CHVA 2FT2A 2AYOA 4I05A 1CSBB 2AU1A 2F1GA 1ITOA 1AYVA 1F2BA 1PPOA 4FK5A 4BSQA 2DCBA 1QXPA 3CH3X 3V6EA 2IPPB 2AS8A 3KX1A 4MZSA 2G6DA 1QDQA 4HWYA 5CHTA 1F29A 1QMYA 2E00A 3H6SA 3HHIA 1KXRA 1PPDA 2NQIA 3U8EA 1NPZA 3MHSA 1CV8A 2AYNA 2Y6EA 2XU1A 3CBKA 4PADA 2ATOA 1CPJA 4YYUA 4QBBA 6PADA 2OP3A 1IWDA 2G7YA 3I3TA 4GUZA 1VJVA 1PBHA 1Q6KA 2FUDA 4XR7A 2NQAA 2O6XA 1KFUL 3IV2A 3BWKA 3PBHA 4X6JA 4W5BA 4N79A 1U9WA 4Q8HA 1TL9A 1U9QX 1YK7A 2DC6A 4YYVA 3E1ZB 3BC3A 4PP1A 1BY8A 4QRVA 5CVOB 3M99A 1F2CA 4X6IA 1THEA 1Y4HA 1BGOA 1NQCA 2VHFA 3GCBA 2DC8A 5K16A 1QOLA 3NHEA 2E03A 3H8CA 2H7JA 1M6DA 1A6RA 4KLBA 3USVA 5JA7A 1U5IA 2DZYA 3F75A 3CBJA 1JQPA 4CDCB 4OELA 4BS5A 5EF4A 4N4ZA 3C9EA 3WXEA 3IHPA 5A24A 1ATKA 1PXVA 2P86A 2BDLA 1TLOA 3S3RA 2YJCA 1CQDA 2FRAA 3K9MA 3WXGA 1VSNA 3IOQA 2NQGA 1U9VA 4DMYA 4YYRA 2XU3A 4AXLA 4C5PA 2YJ8A 1Y08A 1AU4A 4BPVA 5PADA 1POPA 4K7CA 2HXZA 3K24A 1W6FA 2FQ9A 1AU3A 3N3KA 2IBIA 2JQFR 4BS6A 2OZ2A 3LXSA 1ME3A 2ARYA 2DCCA 3KWBX 1U9XA 1EWOA 1CS8A 2DCAA 1YALA 4I04A 3TNXA 1EWPA 3IUTA 4NV7A 2Y5BA 4W5CA 2VFBA 3S3QA 1ZCMA 4FIPA 4PI3A 3B79A 1PPNA 1AECA 4YYSA 3O1GA 1GCBA 1EF7A 5J94A 3F5VA 1MHWA 4WA6A 3DF0A 1NL6A 3N4CA 3MORA 2AIMA 1CVZA 2AVWA 3QJ3A 2HHNA 4XUIA 4PP2E 4OEMA 1MS6A 3WXFA 2DJFB 2F7DA 2R6NA 2YJ2A 4Q8GA 2B1NA 1TU6A 4G54A 7PCKA 1PADA 3KSEA 5EGWA 1CJLA 2R9CA 4ZUXU 3O0UA 4MSXA 1ICFA 3D9WA 4QRXA 3BPMA 4YVAA 1X9YA 1W5RA 1PE6A 2G8EA 3IEJA 1DEUA 2C0YA 1CTEA 1E2TA 5CVMA 1HUCB 3PNRA 1MDWA 4YYWA 4W4UA 1DF0A 4CDFB 3I06A 2HH5A 4I07A 1NB3A 1PCIA 2R9NA 2HD5A 9PAPA 2FYEA 2GHUA 1AU0A 5F02A 3RVWA 4DMXA 1YVBA 3RVXA 1XKGA 2R9FA 1GMYA 3HHAA 1ME4A 3HD3A 1PIPA 4P6EA 1SP4B 8PCHA 2WBFX 3KKUA 1BP4A 2E01A 4FJCA 3OISA 2DZZA 3HWNA 2CB5A 5CVNB 3P5UA 1CB5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4QRG A;  2OUL A;  1SNK A;  2GFO A;  3MHH A;  2XU5 A;  2FTD A;  2PRE A;  3KW9 A;  4CDE B;  4X6H A;  3PDF A;  3AI8 A;  1GEC E;  1O0E A;  3OVZ A;  1AU2 A;  2JQG R;  1S4V A;  2PNS A;  2ACT A;  1GLO A;  3CH2 X;  1NLJ A;  2BDZ A;  3H7D A;  3QSD A;  2G8J A;  4CDD B;  3N3G A;  3IMA A;  1KFX L;  2DC7 A;  3P5W A;  4YV8 A;  1MEG A;  4QH6 A;  2R9M A;  3BOW A;  2DJG B;  5JH3 A;  4AXM A;  2YJ9 A;  2P0R A;  1BQI A;  2FO5 A;  3KWZ A;  4N8W A;  3H8B A;  1PPP A;  2DCD A;  2PBH A;  1STF E;  2P7U A;  3MTN A;  4CZW A;  1AYW A;  1EWL A;  1YK8 A;  2VHS A;  3ERV A;  3OF9 A;  1AIM A;  1KHP A;  3D6S A;  4YYQ A;  3BCN A;  3QT4 A;  1YT7 A;  2CIO A;  5FPW A;  3ZUA A;  4MZO A;  4RY2 A;  1EWM A;  1ZIV A;  1KHQ A;  1AYU A;  1MEM A;  2AUZ A;  2NQD B;  3BPF A;  3K8U A;  1NB5 A;  2AUX A;  2R9O A;  1FH0 A;  2FRQ A;  3P5X A;  1K3B B;  2XU4 A;  3LFY A;  3P5V A;  4P6G A;  2E02 A;  2YJB A;  3RVV A;  2B1M A;  2DC9 A;  3OF8 A;  3KFQ A;  1MIR A;  3H89 A;  4BQV A;  2PAD A;  1F2A A;  3PW3 A;  3OVX A;  3V6C A;  5CHV A;  2FT2 A;  2AYO A;  4I05 A;  1CSB B;  2AU1 A;  2F1G A;  1ITO A;  1AYV A;  1F2B A;  1PPO A;  4FK5 A;  4BSQ A;  2DCB A;  1QXP A;  3CH3 X;  3V6E A;  2IPP B;  2AS8 A;  3KX1 A;  4MZS A;  2G6D A;  1QDQ A;  4HWY A;  5CHT A;  1F29 A;  1QMY A;  2E00 A;  3H6S A;  3HHI A;  1KXR A;  1PPD A;  2NQI A;  3U8E A;  1NPZ A;  3MHS A;  1CV8 A;  2AYN A;  2Y6E A;  2XU1 A;  3CBK A;  4PAD A;  2ATO A;  1CPJ A;  4YYU A;  4QBB A;  6PAD A;  2OP3 A;  1IWD A;  2G7Y A;  3I3T A;  1VJV A;  1PBH A;  1Q6K A;  2FUD A;  4XR7 A;  2NQA A;  2O6X A;  1KFU L;  3IV2 A;  3BWK A;  3PBH A;  4X6J A;  4W5B A;  4N79 A;  1U9W A;  4Q8H A;  1TL9 A;  1U9Q X;  1YK7 A;  2DC6 A;  4YYV A;  3E1Z B;  3BC3 A;  4PP1 A;  1BY8 A;  4QRV A;  5CVO B;  3M99 A;  1F2C A;  4X6I A;  1THE A;  1Y4H A;  1BGO A;  1NQC A;  2VHF A;  3GCB A;  2DC8 A;  5K16 A;  1QOL A;  3NHE A;  2E03 A;  3H8C A;  2H7J A;  1M6D A;  1A6R A;  4KLB A;  3USV A;  5JA7 A;  1U5I A;  2DZY A;  3F75 A;  3CBJ A;  1JQP A;  4CDC B;  4OEL A;  4BS5 A;  5EF4 A;  4N4Z A;  3C9E A;  3WXE A;  3IHP A;  5A24 A;  1ATK A;  1PXV A;  2P86 A;  2BDL A;  1TLO A;  3S3R A;  2YJC A;  1CQD A;  2FRA A;  3K9M A;  3WXG A;  1VSN A;  3IOQ A;  2NQG A;  1U9V A;  4DMY A;  4YYR A;  2XU3 A;  4AXL A;  2YJ8 A;  1Y08 A;  1AU4 A;  4BPV A;  5PAD A;  1POP A;  4K7C A;  2HXZ A;  3K24 A;  2FQ9 A;  1AU3 A;  3N3K A;  2IBI A;  2JQF R;  4BS6 A;  2OZ2 A;  3LXS A;  1ME3 A;  2ARY A;  2DCC A;  3KWB X;  1U9X A;  1EWO A;  1CS8 A;  2DCA A;  1YAL A;  4I04 A;  3TNX A;  1EWP A;  3IUT A;  2Y5B A;  4W5C A;  3S3Q A;  1ZCM A;  4FIP A;  4PI3 A;  3B79 A;  1PPN A;  1AEC A;  4YYS A;  3O1G A;  1GCB A;  1EF7 A;  5J94 A;  3F5V A;  1MHW A;  4WA6 A;  3DF0 A;  1NL6 A;  3N4C A;  3MOR A;  2AIM A;  1CVZ A;  2AVW A;  3QJ3 A;  2HHN A;  4XUI A;  4PP2 E;  4OEM A;  1MS6 A;  3WXF A;  2DJF B;  2F7D A;  2R6N A;  2YJ2 A;  4Q8G A;  2B1N A;  1TU6 A;  4G54 A;  7PCK A;  1PAD A;  3KSE A;  5EGW A;  1CJL A;  2R9C A;  4ZUX U;  3O0U A;  4MSX A;  1ICF A;  4QRX A;  3BPM A;  4YVA A;  1X9Y A;  1PE6 A;  2G8E A;  3IEJ A;  1DEU A;  2C0Y A;  1CTE A;  5CVM A;  1HUC B;  3PNR A;  1MDW A;  4YYW A;  4W4U A;  1DF0 A;  4CDF B;  3I06 A;  2HH5 A;  4I07 A;  1NB3 A;  1PCI A;  2R9N A;  2HD5 A;  9PAP A;  2FYE A;  2GHU A;  1AU0 A;  5F02 A;  3RVW A;  4DMX A;  1YVB A;  3RVX A;  1XKG A;  2R9F A;  1GMY A;  3HHA A;  1ME4 A;  3HD3 A;  1PIP A;  4P6E A;  1SP4 B;  8PCH A;  2WBF X;  3KKU A;  1BP4 A;  2E01 A;  4FJC A;  3OIS A;  2DZZ A;  3HWN A;  2CB5 A;  5CVN B;  3P5U A;  1CB5 A; 
#chains in the Genus database with same CATH topology
 4QRG A;  2OUL A;  1SNK A;  2HWK A;  2JTC A;  2GFO A;  3MHH A;  2XU5 A;  2FTD A;  2PRE A;  1PVJ A;  3KW9 A;  4CDE B;  4X6H A;  3PDF A;  3AI8 A;  1GEC E;  4D8E A;  1O0E A;  3OVZ A;  1AU2 A;  2JQG R;  1S4V A;  2PNS A;  5E6J A;  2ACT A;  1GLO A;  3CH2 X;  1NLJ A;  2BDZ A;  3H7D A;  3QSD A;  4BOU A;  2G8J A;  4CDD B;  3N3G A;  3IMA A;  1KFX L;  2DC7 A;  3P5W A;  4YV8 A;  1MEG A;  4QH6 A;  2R9M A;  3BOW A;  4D8B A;  2DJG B;  5JH3 A;  2JRI A;  4AXM A;  2YJ9 A;  2P0R A;  1BQI A;  2FO5 A;  3KWZ A;  4N8W A;  3H8B A;  1PPP A;  2DCD A;  2PBH A;  1STF E;  2P7U A;  3MTN A;  4D8I A;  4CZW A;  1AYW A;  3W30 A;  1EWL A;  1YK8 A;  2VHS A;  3ERV A;  3B21 A;  1AIM A;  3OF9 A;  2Z84 A;  1KHP A;  3D6S A;  4YYQ A;  3BCN A;  3QT4 A;  1YT7 A;  2CIO A;  5FPW A;  3ZUA A;  4MZO A;  4RY2 A;  3PRM A;  1EWM A;  1ZIV A;  4BOS A;  1KHQ A;  1AYU A;  1MEM A;  2AUZ A;  2NQD B;  3BPF A;  3K8U A;  2FE8 A;  1NB5 A;  3MP2 A;  2AUX A;  2R9O A;  1FH0 A;  2FRQ A;  3P5X A;  1K3B B;  2XU4 A;  3LFY A;  3P5V A;  4P6G A;  2E02 A;  2YJB A;  3RVV A;  2B1M A;  2DC9 A;  3OF8 A;  3KFQ A;  1MIR A;  3H89 A;  4BQV A;  3TRK A;  3TMP A;  2PAD A;  1F2A A;  3PW3 A;  3OVX A;  3V6C A;  5CHV A;  3BBA A;  2FT2 A;  2AYO A;  4I05 A;  1CSB B;  2AU1 A;  2F1G A;  3IFU A;  1ITO A;  1AYV A;  1F2B A;  1PPO A;  4FK5 A;  4BSQ A;  2DCB A;  1QXP A;  3CH3 X;  3V6E A;  2IPP B;  2AS8 A;  3KX1 A;  4MZS A;  2G6D A;  2DOS A;  1QDQ A;  4HWY A;  5CHT A;  1F29 A;  1QMY A;  2E00 A;  3H6S A;  3HHI A;  1KXR A;  1PPD A;  2NQI A;  3U8E A;  1NPZ A;  3MHS A;  1CV8 A;  2AYN A;  2Y6E A;  4MI7 A;  2XU1 A;  3CBK A;  4PAD A;  2ATO A;  1CPJ A;  4YYU A;  4QBB A;  6PAD A;  1UKF A;  2OP3 A;  1IWD A;  2G7Y A;  3I3T A;  4GUA A;  1VJV A;  1PBH A;  1Q6K A;  2FUD A;  4XR7 A;  2NQA A;  5JZE A;  2O6X A;  1KFU L;  3IV2 A;  3BWK A;  3PBH A;  4X6J A;  4W5B A;  3PT2 A;  4N79 A;  1U9W A;  4IP3 A;  4Q8H A;  1TL9 A;  1U9Q X;  1YK7 A;  2DC6 A;  4YYV A;  3E1Z B;  3BC3 A;  4PP1 A;  3W31 A;  1BY8 A;  4QRV A;  5CVO B;  3M99 A;  1F2C A;  4X6I A;  1THE A;  1Y4H A;  1BGO A;  1NQC A;  2VHF A;  3O65 A;  3GCB A;  2DC8 A;  5K16 A;  1QOL A;  3NHE A;  2E03 A;  3H8C A;  4PT5 A;  3BY4 A;  2H7J A;  1M6D A;  1A6R A;  4KLB A;  3USV A;  3PRP A;  5JA7 A;  1U5I A;  2DZY A;  4HXD B;  4A5U A;  3F75 A;  3CBJ A;  1JQP A;  4CDC B;  4OEL A;  4BS5 A;  2BU3 A;  5EF4 A;  4N4Z A;  3C9E A;  3WXE A;  3IHP A;  5A24 A;  5EZS A;  1ATK A;  1PXV A;  2P86 A;  4XZX A;  2BDL A;  1TLO A;  4WUR A;  3S3R A;  2YJC A;  1CQD A;  2FRA A;  3K9M A;  3WXG A;  1VSN A;  3IOQ A;  2NQG A;  2BTW B;  1U9V A;  4DMY A;  4YYR A;  2XU3 A;  4AXL A;  2BTW A;  1YZB A;  2YJ8 A;  4RF0 A;  4REZ A;  1Y08 A;  4P16 A;  1AU4 A;  4BPV A;  5PAD A;  1POP A;  4K7C A;  2HXZ A;  3K24 A;  4M0W A;  2FQ9 A;  1AU3 A;  3N3K A;  2IBI A;  2JQF R;  2J7Q C;  4BS6 A;  2OZ2 A;  3LXS A;  1ME3 A;  2ARY A;  2DCC A;  3KWB X;  1U9X A;  1EWO A;  1CS8 A;  4R3D A;  2DCA A;  1YAL A;  4I04 A;  3TNX A;  3ZNH A;  1EWP A;  3IUT A;  4BOQ A;  2Y5B A;  4W5C A;  3S3Q A;  1DKI A;  3OQC A;  3BB7 A;  1ZCM A;  4FIP A;  4PI3 A;  3B79 A;  1PPN A;  1AEC A;  4YYS A;  3O1G A;  1GCB A;  1EF7 A;  4ZTB A;  5J94 A;  3F5V A;  1MHW A;  4WA6 A;  3DF0 A;  4OVZ B;  3N4C A;  1NL6 A;  3MOR A;  4OVZ A;  2AIM A;  4RKX A;  1CVZ A;  3C0R A;  2AVW A;  3QJ3 A;  3PSE A;  2HHN A;  4RF1 A;  4XUI A;  4PP2 E;  4OEM A;  1MS6 A;  3WXF A;  2DJF B;  2F7D A;  2R6N A;  2YJ2 A;  4Q8G A;  2B1N A;  4RNA A;  1TU6 A;  3E9S A;  4G54 A;  7PCK A;  1PAD A;  3KSE A;  2J7Q A;  5EGW A;  1CJL A;  2R9C A;  5KO3 A;  4ZUX U;  3O0U A;  4MSX A;  1ICF A;  4QRX A;  4BOZ A;  3BPM A;  4YVA A;  1X9Y A;  2AGA A;  1PE6 A;  3RNV A;  2G8E A;  3MTV A;  3IEJ A;  1DEU A;  2C0Y A;  1CTE A;  5CVM A;  1HUC B;  3PNR A;  1MDW A;  4YYW A;  4W4U A;  1DF0 A;  4CDF B;  3I06 A;  2HH5 A;  4I07 A;  1NB3 A;  1PCI A;  2R9N A;  2HD5 A;  9PAP A;  2FYE A;  3PHU A;  2GHU A;  1AU0 A;  5F02 A;  3RVW A;  4DMX A;  1YVB A;  3RVX A;  1XKG A;  3MJ5 A;  2R9F A;  4OW0 A;  3PHX A;  1GMY A;  3HHA A;  1ME4 A;  3HD3 A;  1PIP A;  4P6E A;  1SP4 B;  8PCH A;  2WBF X;  3KKU A;  1BP4 A;  2E01 A;  4FJC A;  4MM3 B;  3OIS A;  2DZZ A;  3HWN A;  2UZJ A;  2CB5 A;  4BOP A;  4IUM A;  5EZQ A;  5CVN B;  3P5U A;  3PHW A;  1CB5 A; 
#chains in the Genus database with same CATH homology
 4QRG A;  2OUL A;  1SNK A;  2GFO A;  3MHH A;  2XU5 A;  2FTD A;  2PRE A;  1W4T A;  3KW9 A;  4CDE B;  4X6H A;  3PDF A;  3AI8 A;  1GEC E;  1O0E A;  3OVZ A;  1AU2 A;  2JQG R;  1S4V A;  4NV8 A;  2PNS A;  2ACT A;  1GLO A;  3CH2 X;  1NLJ A;  3LTW A;  2BDZ A;  3H7D A;  3QSD A;  2VFC A;  2G8J A;  4CDD B;  3N3G A;  4BGF A;  3IMA A;  1KFX L;  2DC7 A;  3P5W A;  4YV8 A;  1MEG A;  4QH6 A;  2R9M A;  3BOW A;  2DJG B;  5JH3 A;  4AXM A;  2YJ9 A;  2P0R A;  1BQI A;  2FO5 A;  3KWZ A;  4N8W A;  3H8B A;  1PPP A;  2DCD A;  1GX3 A;  2PBH A;  1STF E;  2P7U A;  3MTN A;  4CZW A;  1AYW A;  1EWL A;  1YK8 A;  2VHS A;  3ERV A;  3OF9 A;  1AIM A;  1KHP A;  3D6S A;  4YYQ A;  3BCN A;  3QT4 A;  1YT7 A;  2CIO A;  5FPW A;  3ZUA A;  4B55 A;  4MZO A;  4RY2 A;  1EWM A;  1ZIV A;  1KHQ A;  1AYU A;  1MEM A;  2AUZ A;  2NQD B;  3BPF A;  3K8U A;  1NB5 A;  2AUX A;  2BSZ A;  2R9O A;  1FH0 A;  2FRQ A;  3P5X A;  1K3B B;  2XU4 A;  3LFY A;  3P5V A;  4P6G A;  2E02 A;  2YJB A;  3RVV A;  2B1M A;  2DC9 A;  3OF8 A;  3KFQ A;  1MIR A;  3H89 A;  4BQV A;  2PAD A;  1F2A A;  3PW3 A;  3OVX A;  3V6C A;  5CHV A;  2FT2 A;  2AYO A;  4I05 A;  1CSB B;  2AU1 A;  2F1G A;  1ITO A;  1AYV A;  1F2B A;  1PPO A;  4FK5 A;  4BSQ A;  2DCB A;  1QXP A;  3CH3 X;  3V6E A;  2IPP B;  2AS8 A;  3KX1 A;  4MZS A;  2G6D A;  1QDQ A;  4HWY A;  5CHT A;  1F29 A;  1QMY A;  2E00 A;  3H6S A;  3HHI A;  1KXR A;  1PPD A;  2NQI A;  3U8E A;  1NPZ A;  3MHS A;  1CV8 A;  2AYN A;  2Y6E A;  2XU1 A;  3CBK A;  4PAD A;  2ATO A;  1CPJ A;  4YYU A;  4QBB A;  6PAD A;  2OP3 A;  1IWD A;  2G7Y A;  3I3T A;  4GUZ A;  1VJV A;  1PBH A;  1Q6K A;  2FUD A;  4XR7 A;  2NQA A;  2O6X A;  1KFU L;  3IV2 A;  3BWK A;  3PBH A;  4X6J A;  4W5B A;  4N79 A;  1U9W A;  4Q8H A;  1TL9 A;  1U9Q X;  1YK7 A;  2DC6 A;  4YYV A;  3E1Z B;  3BC3 A;  4PP1 A;  1BY8 A;  4QRV A;  5CVO B;  3M99 A;  1F2C A;  4X6I A;  1THE A;  1Y4H A;  1BGO A;  1NQC A;  2VHF A;  3GCB A;  2DC8 A;  5K16 A;  1QOL A;  3NHE A;  2E03 A;  3H8C A;  2H7J A;  1M6D A;  1A6R A;  4KLB A;  3USV A;  5JA7 A;  1U5I A;  2DZY A;  3F75 A;  3CBJ A;  1JQP A;  4CDC B;  4OEL A;  4BS5 A;  5EF4 A;  4N4Z A;  3C9E A;  3WXE A;  3IHP A;  5A24 A;  1ATK A;  1PXV A;  2P86 A;  2BDL A;  1TLO A;  3S3R A;  2YJC A;  1CQD A;  2FRA A;  3K9M A;  3WXG A;  1VSN A;  3IOQ A;  2NQG A;  1U9V A;  4DMY A;  4YYR A;  2XU3 A;  4AXL A;  4C5P A;  2YJ8 A;  1Y08 A;  1AU4 A;  4BPV A;  5PAD A;  1POP A;  4K7C A;  2HXZ A;  3K24 A;  1W6F A;  2FQ9 A;  1AU3 A;  3N3K A;  2IBI A;  2JQF R;  4BS6 A;  2OZ2 A;  3LXS A;  1ME3 A;  2ARY A;  2DCC A;  3KWB X;  1U9X A;  1EWO A;  1CS8 A;  2DCA A;  1YAL A;  4I04 A;  3TNX A;  1EWP A;  3IUT A;  4NV7 A;  2Y5B A;  4W5C A;  2VFB A;  3S3Q A;  1ZCM A;  4FIP A;  4PI3 A;  3B79 A;  1PPN A;  1AEC A;  4YYS A;  3O1G A;  1GCB A;  1EF7 A;  5J94 A;  3F5V A;  1MHW A;  4WA6 A;  3DF0 A;  1NL6 A;  3N4C A;  3MOR A;  2AIM A;  1CVZ A;  2AVW A;  3QJ3 A;  2HHN A;  4XUI A;  4PP2 E;  4OEM A;  1MS6 A;  3WXF A;  2DJF B;  2F7D A;  2R6N A;  2YJ2 A;  4Q8G A;  2B1N A;  1TU6 A;  4G54 A;  7PCK A;  1PAD A;  3KSE A;  5EGW A;  1CJL A;  2R9C A;  4ZUX U;  3O0U A;  4MSX A;  1ICF A;  3D9W A;  4QRX A;  3BPM A;  4YVA A;  1X9Y A;  1W5R A;  1PE6 A;  2G8E A;  3IEJ A;  1DEU A;  2C0Y A;  1CTE A;  1E2T A;  5CVM A;  1HUC B;  3PNR A;  1MDW A;  4YYW A;  4W4U A;  1DF0 A;  4CDF B;  3I06 A;  2HH5 A;  4I07 A;  1NB3 A;  1PCI A;  2R9N A;  2HD5 A;  9PAP A;  2FYE A;  2GHU A;  1AU0 A;  5F02 A;  3RVW A;  4DMX A;  1YVB A;  3RVX A;  1XKG A;  2R9F A;  1GMY A;  3HHA A;  1ME4 A;  3HD3 A;  1PIP A;  4P6E A;  1SP4 B;  8PCH A;  2WBF X;  3KKU A;  1BP4 A;  2E01 A;  4FJC A;  3OIS A;  2DZZ A;  3HWN A;  2CB5 A;  5CVN B;  3P5U A;  1CB5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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