4AXLA

Human cathepsin l apo form with zn
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
220
structure length
220
Chain Sequence
APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords CATHEPSIN L1
publication title Optimization of Triazine Nitriles as Rhodesain Inhibitors: Structure-Activity Relationships, Bioisosteric Imidazopyridine Nitriles, and X-Ray Crystal Structure Analysis with Human Cathepsin L
pubmed doi rcsb
source organism Homo sapiens
total genus 68
structure length 220
sequence length 220
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2012-06-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 4axlA00
3TNXA 3H8BA 3N3KA 1VJVA 3PDFA 2FYEA 3RVWA 1MEMA 3C9EA 2HH5A 2DC7A 2F1GA 2DCBA 2DC6A 4DMYA 1PPDA 3BPFA 3F75A 3WXFA 3I06A 2G7YA 1Y4HA 3O1GA 1AU3A 3NHEA 1EWLA 1CPJA 3IOQA 1F29A 4YV8A 1BP4A 1AU4A 3P5WA 4MZSA 1CQDA 4QRGA 1PIPA 2FO5A 3N3GA 1AU2A 3OISA 4CDEB 2CIOA 1U5IA 3BCNA 5PADA 3KSEA 3QSDA 4BPVA 3H8CA 4FJCA 3RVXA 5CVNB 3M99A 4QH6A 2GFOA 5CHVA 1MS6A 1PPPA 2R9NA 1QDQA 4WA6A 4BS6A 4I07A 4Q8GA 1NL6A 1HUCB 1YK8A 3H7DA 1KFUL 4P6GA 4Q8HA 4N4ZA 3WXGA 1AYWA 4QBBA 1MEGA 3O0UA 2DCDA 1IWDA 1QMYA 3D6SA 2XU4A 7PCKA 5J94A 1NB5A 4I04A 2C0YA 1Q6KA 1AU0A 1PBHA 1U9QX 2AVWA 2BDLA 3CH3X 3OF9A 1GLOA 2DCCA 2ATOA 2G6DA 5CVOB 1KHPA 3IV2A 3P5XA 4MSXA 2R9MA 5EGWA 1ME3A 4N79A 1EWOA 3PW3A 4W4UA 4AXMA 3K24A 4XUIA 4CDDB 2AS8A 5F02A 4HWYA 1CVZA 1DF0A 1M6DA 2DCAA 2GHUA 1YT7A 1Y08A 1U9WA 2G8EA 1NQCA 3K9MA 3IEJA 1ZCMA 3OVZA 3MTNA 2B1MA 2AIMA 5EF4A 2PNSA 1CV8A 1EF7A 1PCIA 1AYVA 2YJCA 3IMAA 1ITOA 3CH2X 2OP3A 3H89A 4X6IA 2WBFX 2ARYA 2ACTA 2DJGB 2DZZA 3USVA 3MORA 1AIMA 1TLOA 1GMYA 2E03A 3BWKA 4YYQA 3IHPA 3ZUAA 3DF0A 2XU5A 4KLBA 2E00A 5A24A 4MZOA 2PBHA 3H6SA 3HWNA 3MHHA 6PADA 2VHSA 3PBHA 2F7DA 4CDFB 3S3QA 3MHSA 4I05A 3S3RA 4P6EA 4DMXA 1S4VA 4OEMA 1STFE 4PADA 5CVMA 2FRQA 2OZ2A 4PP2E 1K3BB 1GECE 5JA7A 2XU1A 3HD3A 2G8JA 1PPNA 4YYWA 1ZIVA 1BY8A 1AECA 2P86A 1GCBA 3B79A 1PE6A 2YJ8A 3AI8A 4K7CA 3E1ZB 1TU6A 2E02A 1PPOA 1EWMA 3KWBX 2FTDA 1A6RA 3P5UA 1YVBA 1ME4A 3HHIA 3PNRA 2BDZA 2YJ2A 2HHNA 4CZWA 1BQIA 2HD5A 3LFYA 1MIRA 1AYUA 3K8UA 4YYVA 3I3TA 2VHFA 1ATKA 2FQ9A 4W5BA 2JQFR 3KWZA 4PI3A 3OVXA 1CS8A 1MDWA 2AUZA 1SNKA 2NQIA 2JQGR 3V6CA 4YYSA 1F2CA 1CB5A 1TL9A 3KFQA 1ICFA 2AYOA 1NLJA 4QRVA 2NQAA 3V6EA 4BQVA 1F2BA 2YJ9A 4YVAA 3CBJA 2DC9A 9PAPA 1X9YA 1FH0A 1KFXL 2AYNA 3BC3A 1U9VA 3BOWA 2PREA 4QRXA 5CHTA 2H7JA 2AU1A 2CB5A 4YYUA 5FPWA 2HXZA 1EWPA 1XKGA 3KW9A 2XU3A 4N8WA 4X6HA 1PADA 2O6XA 1VSNA 3N4CA 2R9OA 3WXEA 1JQPA 2DC8A 2NQDB 4AXLA 1DEUA 2R9CA 3F5VA 4BS5A 4BSQA 2R9FA 2IBIA 3CBKA 2Y5BA 3QT4A 1CSBB 3GCBA 3BPMA 1QOLA 4W5CA 2OULA 1CJLA 4ZUXU 2P7UA 1PXVA 3KX1A 2DZYA 3P5VA 2FUDA 4CDCB 4PP1A 2PADA 2NQGA 1SP4B 2DJFB 1BGOA 3KKUA 4RY2A 2Y6EA 1YK7A 2E01A 3ERVA 1NB3A 5K16A 2YJBA 4XR7A 1POPA 1U9XA 2IPPB 2B1NA 5JH3A 3IUTA 1KXRA 2FRAA 4X6JA 1NPZA 3RVVA 3OF8A 1KHQA 1O0EA 2FT2A 1CTEA 1MHWA 2AUXA 2R6NA 3U8EA 4YYRA 1THEA 2P0RA 8PCHA 1YALA 4OELA 3LXSA 3QJ3A 3HHAA 4G54A 1F2AA 4FIPA 4FK5A 1QXPA
chains in the Genus database with same CATH superfamily
3TNXA 4BOZA 3B21A 3H8BA 3N3KA 1VJVA 3PDFA 2FYEA 3RVWA 2BU3A 1MEMA 3C9EA 2HH5A 2DC7A 2F1GA 2DCBA 2DC6A 4DMYA 1PPDA 3BPFA 3F75A 3WXFA 3I06A 2G7YA 1Y4HA 3MP2A 3O1GA 1AU3A 3NHEA 1EWLA 1CPJA 3IOQA 1F29A 2AGAA 4YV8A 1BP4A 1AU4A 3P5WA 4MZSA 1CQDA 4QRGA 3PHWA 1PIPA 2FO5A 3N3GA 1AU2A 3OISA 3MTVA 4CDEB 2CIOA 2J7QC 1U5IA 3BCNA 5PADA 3KSEA 4WURA 3QSDA 4BPVA 3H8CA 4FJCA 3RVXA 3E9SA 3W31A 5CVNB 3M99A 4QH6A 2GFOA 4REZA 3PHXA 5CHVA 1MS6A 1PPPA 2R9NA 1QDQA 4WA6A 3BB7A 4BS6A 4I07A 4Q8GA 1NL6A 1HUCB 1YK8A 3H7DA 3W30A 1KFUL 4P6GA 4Q8HA 4N4ZA 3WXGA 1AYWA 4QBBA 1MEGA 3PT2A 3O0UA 4R3DA 2DCDA 1IWDA 1QMYA 3D6SA 2XU4A 7PCKA 5J94A 1NB5A 4I04A 2C0YA 5EZQA 1Q6KA 1AU0A 1PBHA 1U9QX 2AVWA 2BDLA 3CH3X 3OF9A 1PVJA 1GLOA 2DCCA 3OQCA 2ATOA 2FE8A 2G6DA 5CVOB 1KHPA 3IV2A 3P5XA 4MSXA 2R9MA 5EGWA 1ME3A 4N79A 1EWOA 3PHUA 3PW3A 4W4UA 4MM3B 4AXMA 3K24A 4XUIA 4CDDB 2AS8A 5F02A 4HWYA 1CVZA 1DF0A 1M6DA 4IUMA 5EZSA 2DCAA 2GHUA 1YT7A 3C0RA 1Y08A 1U9WA 2G8EA 3IFUA 4BOQA 1NQCA 3K9MA 3TRKA 3IEJA 1ZCMA 3OVZA 3MTNA 2B1MA 2AIMA 5EF4A 4P16A 2PNSA 1CV8A 1EF7A 1PCIA 1AYVA 2YJCA 3IMAA 1ITOA 3CH2X 2OP3A 3H89A 4X6IA 2WBFX 4ZTBA 2ARYA 2ACTA 2DJGB 2DZZA 3USVA 3MORA 4RF1A 1AIMA 2DOSA 3PRMA 1TLOA 1GMYA 2E03A 3BWKA 4YYQA 3IHPA 3ZUAA 3DF0A 1DKIA 2XU5A 2J7QA 4GUAA 4KLBA 2E00A 5A24A 4MZOA 4RNAA 2PBHA 3BBAA 3H6SA 3HWNA 3MHHA 6PADA 5JZEA 4MI7A 2VHSA 3PBHA 2F7DA 4CDFB 4XZXA 3S3QA 3MHSA 4I05A 3S3RA 4P6EA 4DMXA 1S4VA 4OEMA 1STFE 4PADA 5CVMA 4IP3A 2HWKA 2FRQA 2OZ2A 4PP2E 1K3BB 1GECE 5JA7A 2XU1A 3HD3A 4OVZA 3PSEA 2G8JA 4D8BA 1PPNA 4YYWA 1ZIVA 4M0WA 1BY8A 1AECA 2P86A 4OW0A 1GCBA 3B79A 1PE6A 2YJ8A 3AI8A 4K7CA 3E1ZB 1TU6A 3TMPA 2E02A 1PPOA 1EWMA 3KWBX 2FTDA 1A6RA 3P5UA 1YVBA 1ME4A 3HHIA 3PNRA 2BDZA 1UKFA 2YJ2A 2HHNA 4CZWA 1BQIA 2HD5A 3LFYA 1MIRA 1AYUA 3K8UA 3ZNHA 4YYVA 3I3TA 2VHFA 1ATKA 2FQ9A 4W5BA 2JQFR 3KWZA 4PI3A 3OVXA 1CS8A 1MDWA 2AUZA 1SNKA 2NQIA 2JQGR 3V6CA 4YYSA 3RNVA 1F2CA 1CB5A 1TL9A 3KFQA 1ICFA 2AYOA 1NLJA 4QRVA 4HXDB 2NQAA 3V6EA 5KO3A 4BQVA 1F2BA 2YJ9A 4YVAA 3CBJA 2DC9A 9PAPA 1X9YA 1FH0A 1KFXL 2AYNA 3BC3A 1U9VA 3BOWA 2PREA 4QRXA 5CHTA 2H7JA 2AU1A 4OVZB 2CB5A 3MJ5A 4YYUA 5FPWA 2HXZA 1EWPA 1XKGA 3KW9A 2XU3A 4N8WA 4X6HA 4RKXA 1PADA 2O6XA 4RF0A 1VSNA 3N4CA 2R9OA 3WXEA 1JQPA 4PT5A 3O65A 2DC8A 2Z84A 2NQDB 4AXLA 1DEUA 2R9CA 3F5VA 4BS5A 4BSQA 2R9FA 5E6JA 2IBIA 3CBKA 2Y5BA 3QT4A 1CSBB 3GCBA 3BPMA 4BOSA 2BTWB 1QOLA 4W5CA 2OULA 1CJLA 4ZUXU 2P7UA 1PXVA 3KX1A 2DZYA 3P5VA 2FUDA 4D8IA 2UZJA 4CDCB 4PP1A 2PADA 2NQGA 1SP4B 2DJFB 1BGOA 3KKUA 4RY2A 2Y6EA 1YK7A 2E01A 3ERVA 1NB3A 5K16A 2YJBA 4A5UA 4XR7A 1POPA 1U9XA 2IPPB 2B1NA 5JH3A 2JRIA 3IUTA 1KXRA 2FRAA 4X6JA 1NPZA 3RVVA 3OF8A 1KHQA 3PRPA 1O0EA 3BY4A 2JTCA 2BTWA 2FT2A 1CTEA 1MHWA 2AUXA 2R6NA 1YZBA 3U8EA 4D8EA 4YYRA 4BOPA 1THEA 2P0RA 8PCHA 1YALA 4OELA 3LXSA 3QJ3A 3HHAA 4G54A 1F2AA 4BOUA 4FIPA 4FK5A 1QXPA
chains in the Genus database with same CATH topology
3TNXA 3H8BA 3N3KA 1VJVA 3PDFA 2FYEA 3RVWA 1MEMA 3C9EA 2HH5A 2DC7A 2F1GA 2DCBA 2DC6A 4DMYA 1PPDA 3BPFA 3F75A 3WXFA 3I06A 2G7YA 1Y4HA 3O1GA 1AU3A 3NHEA 1EWLA 1CPJA 3IOQA 1F29A 4YV8A 1BP4A 1AU4A 3P5WA 4MZSA 1CQDA 4QRGA 1PIPA 2FO5A 3N3GA 1AU2A 3OISA 4CDEB 2CIOA 1U5IA 3BCNA 5PADA 4C5PA 3KSEA 3QSDA 4BPVA 3H8CA 4FJCA 3RVXA 5CVNB 3M99A 4QH6A 4GUZA 1W6FA 2GFOA 5CHVA 1MS6A 1PPPA 2R9NA 1QDQA 3LTWA 4WA6A 4BS6A 4I07A 4Q8GA 1NL6A 1HUCB 1YK8A 3H7DA 1KFUL 4P6GA 4Q8HA 4N4ZA 3WXGA 1AYWA 4QBBA 1MEGA 3O0UA 2DCDA 1IWDA 1QMYA 3D6SA 2XU4A 7PCKA 5J94A 1NB5A 4I04A 2C0YA 1Q6KA 1AU0A 2BSZA 1PBHA 1U9QX 2AVWA 2BDLA 3CH3X 3OF9A 1GLOA 2DCCA 2ATOA 2G6DA 5CVOB 1KHPA 3IV2A 3P5XA 4MSXA 2R9MA 5EGWA 1ME3A 4N79A 1EWOA 3PW3A 4W4UA 4AXMA 3K24A 4XUIA 4CDDB 2AS8A 5F02A 4HWYA 1CVZA 1DF0A 1M6DA 2DCAA 2GHUA 1YT7A 1Y08A 1U9WA 2G8EA 1NQCA 3K9MA 3IEJA 1ZCMA 3OVZA 3MTNA 2B1MA 2AIMA 5EF4A 2PNSA 1CV8A 1EF7A 1PCIA 1AYVA 2YJCA 2VFBA 3IMAA 1ITOA 3CH2X 2OP3A 3H89A 4X6IA 2WBFX 2ARYA 2ACTA 2DJGB 2DZZA 3USVA 3MORA 1AIMA 4BGFA 1TLOA 1GMYA 2E03A 3BWKA 4YYQA 3IHPA 3ZUAA 3DF0A 2XU5A 4KLBA 2E00A 5A24A 4MZOA 2PBHA 3H6SA 3HWNA 3MHHA 4NV7A 6PADA 2VHSA 3PBHA 2F7DA 4CDFB 3S3QA 3MHSA 4I05A 3S3RA 4P6EA 4DMXA 1S4VA 4OEMA 1STFE 4PADA 5CVMA 2FRQA 2OZ2A 4PP2E 1K3BB 1GECE 5JA7A 2XU1A 3HD3A 2G8JA 1PPNA 4YYWA 1ZIVA 1BY8A 1AECA 2P86A 1GCBA 3B79A 1PE6A 2YJ8A 3AI8A 4K7CA 3E1ZB 1TU6A 2E02A 1PPOA 1EWMA 3KWBX 2FTDA 1A6RA 3P5UA 1YVBA 1ME4A 3HHIA 3PNRA 2BDZA 2YJ2A 2HHNA 4CZWA 1BQIA 2HD5A 3LFYA 1MIRA 1AYUA 3K8UA 4YYVA 3I3TA 2VHFA 1ATKA 2FQ9A 4W5BA 2JQFR 3KWZA 4PI3A 3OVXA 1CS8A 1MDWA 2AUZA 1SNKA 2NQIA 2JQGR 3V6CA 4NV8A 4YYSA 1F2CA 1CB5A 1TL9A 3KFQA 1ICFA 2AYOA 1NLJA 4QRVA 2NQAA 3V6EA 4BQVA 1F2BA 2YJ9A 4YVAA 3CBJA 2DC9A 9PAPA 1X9YA 1FH0A 1KFXL 2AYNA 3BC3A 1U9VA 3BOWA 2PREA 4QRXA 5CHTA 2H7JA 2AU1A 2CB5A 4YYUA 5FPWA 2HXZA 1EWPA 2VFCA 1XKGA 3KW9A 2XU3A 4N8WA 4X6HA 1PADA 2O6XA 1VSNA 3N4CA 2R9OA 3WXEA 1JQPA 2DC8A 2NQDB 4AXLA 1DEUA 2R9CA 3F5VA 4BS5A 4BSQA 2R9FA 2IBIA 3CBKA 2Y5BA 1E2TA 3QT4A 1CSBB 3D9WA 3GCBA 3BPMA 1QOLA 4W5CA 2OULA 1W5RA 1CJLA 4ZUXU 2P7UA 1PXVA 3KX1A 2DZYA 3P5VA 2FUDA 4CDCB 4PP1A 2PADA 2NQGA 1SP4B 2DJFB 1W4TA 1BGOA 3KKUA 4RY2A 2Y6EA 1YK7A 2E01A 3ERVA 1NB3A 5K16A 2YJBA 4XR7A 1POPA 1U9XA 2IPPB 2B1NA 5JH3A 3IUTA 1KXRA 2FRAA 4X6JA 1NPZA 3RVVA 3OF8A 1KHQA 1O0EA 4B55A 2FT2A 1CTEA 1MHWA 2AUXA 2R6NA 3U8EA 4YYRA 1THEA 2P0RA 8PCHA 1YALA 4OELA 3LXSA 1GX3A 3QJ3A 3HHAA 4G54A 1F2AA 4FIPA 4FK5A 1QXPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TNX A;  3H8B A;  3N3K A;  1VJV A;  3PDF A;  2FYE A;  3RVW A;  1MEM A;  3C9E A;  2HH5 A;  2DC7 A;  2F1G A;  2DCB A;  2DC6 A;  4DMY A;  1PPD A;  3BPF A;  3F75 A;  3WXF A;  3I06 A;  2G7Y A;  1Y4H A;  3O1G A;  1AU3 A;  3NHE A;  1EWL A;  1CPJ A;  3IOQ A;  1F29 A;  4YV8 A;  1BP4 A;  1AU4 A;  3P5W A;  4MZS A;  1CQD A;  4QRG A;  1PIP A;  2FO5 A;  3N3G A;  1AU2 A;  3OIS A;  4CDE B;  2CIO A;  1U5I A;  3BCN A;  5PAD A;  3KSE A;  3QSD A;  4BPV A;  3H8C A;  4FJC A;  3RVX A;  5CVN B;  3M99 A;  4QH6 A;  2GFO A;  5CHV A;  1MS6 A;  1PPP A;  2R9N A;  1QDQ A;  4WA6 A;  4BS6 A;  4I07 A;  4Q8G A;  1NL6 A;  1HUC B;  1YK8 A;  3H7D A;  1KFU L;  4P6G A;  4Q8H A;  4N4Z A;  3WXG A;  1AYW A;  4QBB A;  1MEG A;  3O0U A;  2DCD A;  1IWD A;  1QMY A;  3D6S A;  2XU4 A;  7PCK A;  5J94 A;  1NB5 A;  4I04 A;  2C0Y A;  1Q6K A;  1AU0 A;  1PBH A;  1U9Q X;  2AVW A;  2BDL A;  3CH3 X;  3OF9 A;  1GLO A;  2DCC A;  2ATO A;  2G6D A;  5CVO B;  1KHP A;  3IV2 A;  3P5X A;  4MSX A;  2R9M A;  5EGW A;  1ME3 A;  4N79 A;  1EWO A;  3PW3 A;  4W4U A;  4AXM A;  3K24 A;  4XUI A;  4CDD B;  2AS8 A;  5F02 A;  4HWY A;  1CVZ A;  1DF0 A;  1M6D A;  2DCA A;  2GHU A;  1YT7 A;  1Y08 A;  1U9W A;  2G8E A;  1NQC A;  3K9M A;  3IEJ A;  1ZCM A;  3OVZ A;  3MTN A;  2B1M A;  2AIM A;  5EF4 A;  2PNS A;  1CV8 A;  1EF7 A;  1PCI A;  1AYV A;  2YJC A;  3IMA A;  1ITO A;  3CH2 X;  2OP3 A;  3H89 A;  4X6I A;  2WBF X;  2ARY A;  2ACT A;  2DJG B;  2DZZ A;  3USV A;  3MOR A;  1AIM A;  1TLO A;  1GMY A;  2E03 A;  3BWK A;  4YYQ A;  3IHP A;  3ZUA A;  3DF0 A;  2XU5 A;  4KLB A;  2E00 A;  5A24 A;  4MZO A;  2PBH A;  3H6S A;  3HWN A;  3MHH A;  6PAD A;  2VHS A;  3PBH A;  2F7D A;  4CDF B;  3S3Q A;  3MHS A;  4I05 A;  3S3R A;  4P6E A;  4DMX A;  1S4V A;  4OEM A;  1STF E;  4PAD A;  5CVM A;  2FRQ A;  2OZ2 A;  4PP2 E;  1K3B B;  1GEC E;  5JA7 A;  2XU1 A;  3HD3 A;  2G8J A;  1PPN A;  4YYW A;  1ZIV A;  1BY8 A;  1AEC A;  2P86 A;  1GCB A;  3B79 A;  1PE6 A;  2YJ8 A;  3AI8 A;  4K7C A;  3E1Z B;  1TU6 A;  2E02 A;  1PPO A;  1EWM A;  3KWB X;  2FTD A;  1A6R A;  3P5U A;  1YVB A;  1ME4 A;  3HHI A;  3PNR A;  2BDZ A;  2YJ2 A;  2HHN A;  4CZW A;  1BQI A;  2HD5 A;  3LFY A;  1MIR A;  1AYU A;  3K8U A;  4YYV A;  3I3T A;  2VHF A;  1ATK A;  2FQ9 A;  4W5B A;  2JQF R;  3KWZ A;  4PI3 A;  3OVX A;  1CS8 A;  1MDW A;  2AUZ A;  1SNK A;  2NQI A;  2JQG R;  3V6C A;  4YYS A;  1F2C A;  1CB5 A;  1TL9 A;  3KFQ A;  1ICF A;  2AYO A;  1NLJ A;  4QRV A;  2NQA A;  3V6E A;  4BQV A;  1F2B A;  2YJ9 A;  4YVA A;  3CBJ A;  2DC9 A;  9PAP A;  1X9Y A;  1FH0 A;  1KFX L;  2AYN A;  3BC3 A;  1U9V A;  3BOW A;  2PRE A;  4QRX A;  5CHT A;  2H7J A;  2AU1 A;  2CB5 A;  4YYU A;  5FPW A;  2HXZ A;  1EWP A;  1XKG A;  3KW9 A;  2XU3 A;  4N8W A;  4X6H A;  1PAD A;  2O6X A;  1VSN A;  3N4C A;  2R9O A;  3WXE A;  1JQP A;  2DC8 A;  2NQD B;  4AXL A;  1DEU A;  2R9C A;  3F5V A;  4BS5 A;  4BSQ A;  2R9F A;  2IBI A;  3CBK A;  2Y5B A;  3QT4 A;  1CSB B;  3GCB A;  3BPM A;  1QOL A;  4W5C A;  2OUL A;  1CJL A;  4ZUX U;  2P7U A;  1PXV A;  3KX1 A;  2DZY A;  3P5V A;  2FUD A;  4CDC B;  4PP1 A;  2PAD A;  2NQG A;  1SP4 B;  2DJF B;  1BGO A;  3KKU A;  4RY2 A;  2Y6E A;  1YK7 A;  2E01 A;  3ERV A;  1NB3 A;  5K16 A;  2YJB A;  4XR7 A;  1POP A;  1U9X A;  2IPP B;  2B1N A;  5JH3 A;  3IUT A;  1KXR A;  2FRA A;  4X6J A;  1NPZ A;  3RVV A;  3OF8 A;  1KHQ A;  1O0E A;  2FT2 A;  1CTE A;  1MHW A;  2AUX A;  2R6N A;  3U8E A;  4YYR A;  1THE A;  2P0R A;  8PCH A;  1YAL A;  4OEL A;  3LXS A;  3QJ3 A;  3HHA A;  4G54 A;  1F2A A;  4FIP A;  4FK5 A;  1QXP A; 
#chains in the Genus database with same CATH topology
 3TNX A;  4BOZ A;  3B21 A;  3H8B A;  3N3K A;  1VJV A;  3PDF A;  2FYE A;  3RVW A;  2BU3 A;  1MEM A;  3C9E A;  2HH5 A;  2DC7 A;  2F1G A;  2DCB A;  2DC6 A;  4DMY A;  1PPD A;  3BPF A;  3F75 A;  3WXF A;  3I06 A;  2G7Y A;  1Y4H A;  3MP2 A;  3O1G A;  1AU3 A;  3NHE A;  1EWL A;  1CPJ A;  3IOQ A;  1F29 A;  2AGA A;  4YV8 A;  1BP4 A;  1AU4 A;  3P5W A;  4MZS A;  1CQD A;  4QRG A;  3PHW A;  1PIP A;  2FO5 A;  3N3G A;  1AU2 A;  3OIS A;  3MTV A;  4CDE B;  2CIO A;  2J7Q C;  1U5I A;  3BCN A;  5PAD A;  3KSE A;  4WUR A;  3QSD A;  4BPV A;  3H8C A;  4FJC A;  3RVX A;  3E9S A;  3W31 A;  5CVN B;  3M99 A;  4QH6 A;  2GFO A;  4REZ A;  3PHX A;  5CHV A;  1MS6 A;  1PPP A;  2R9N A;  1QDQ A;  4WA6 A;  3BB7 A;  4BS6 A;  4I07 A;  4Q8G A;  1NL6 A;  1HUC B;  1YK8 A;  3H7D A;  3W30 A;  1KFU L;  4P6G A;  4Q8H A;  4N4Z A;  3WXG A;  1AYW A;  4QBB A;  1MEG A;  3PT2 A;  3O0U A;  4R3D A;  2DCD A;  1IWD A;  1QMY A;  3D6S A;  2XU4 A;  7PCK A;  5J94 A;  1NB5 A;  4I04 A;  2C0Y A;  5EZQ A;  1Q6K A;  1AU0 A;  1PBH A;  1U9Q X;  2AVW A;  2BDL A;  3CH3 X;  3OF9 A;  1PVJ A;  1GLO A;  2DCC A;  3OQC A;  2ATO A;  2FE8 A;  2G6D A;  5CVO B;  1KHP A;  3IV2 A;  3P5X A;  4MSX A;  2R9M A;  5EGW A;  1ME3 A;  4N79 A;  1EWO A;  3PHU A;  3PW3 A;  4W4U A;  4MM3 B;  4AXM A;  3K24 A;  4XUI A;  4CDD B;  2AS8 A;  5F02 A;  4HWY A;  1CVZ A;  1DF0 A;  1M6D A;  4IUM A;  5EZS A;  2DCA A;  2GHU A;  1YT7 A;  3C0R A;  1Y08 A;  1U9W A;  2G8E A;  3IFU A;  4BOQ A;  1NQC A;  3K9M A;  3TRK A;  3IEJ A;  1ZCM A;  3OVZ A;  3MTN A;  2B1M A;  2AIM A;  5EF4 A;  4P16 A;  2PNS A;  1CV8 A;  1EF7 A;  1PCI A;  1AYV A;  2YJC A;  3IMA A;  1ITO A;  3CH2 X;  2OP3 A;  3H89 A;  4X6I A;  2WBF X;  4ZTB A;  2ARY A;  2ACT A;  2DJG B;  2DZZ A;  3USV A;  3MOR A;  4RF1 A;  1AIM A;  2DOS A;  3PRM A;  1TLO A;  1GMY A;  2E03 A;  3BWK A;  4YYQ A;  3IHP A;  3ZUA A;  3DF0 A;  1DKI A;  2XU5 A;  2J7Q A;  4GUA A;  4KLB A;  2E00 A;  5A24 A;  4MZO A;  4RNA A;  2PBH A;  3BBA A;  3H6S A;  3HWN A;  3MHH A;  6PAD A;  5JZE A;  4MI7 A;  2VHS A;  3PBH A;  2F7D A;  4CDF B;  4XZX A;  3S3Q A;  3MHS A;  4I05 A;  3S3R A;  4P6E A;  4DMX A;  1S4V A;  4OEM A;  1STF E;  4PAD A;  5CVM A;  4IP3 A;  2HWK A;  2FRQ A;  2OZ2 A;  4PP2 E;  1K3B B;  1GEC E;  5JA7 A;  2XU1 A;  3HD3 A;  4OVZ A;  3PSE A;  2G8J A;  4D8B A;  1PPN A;  4YYW A;  1ZIV A;  4M0W A;  1BY8 A;  1AEC A;  2P86 A;  4OW0 A;  1GCB A;  3B79 A;  1PE6 A;  2YJ8 A;  3AI8 A;  4K7C A;  3E1Z B;  1TU6 A;  3TMP A;  2E02 A;  1PPO A;  1EWM A;  3KWB X;  2FTD A;  1A6R A;  3P5U A;  1YVB A;  1ME4 A;  3HHI A;  3PNR A;  2BDZ A;  1UKF A;  2YJ2 A;  2HHN A;  4CZW A;  1BQI A;  2HD5 A;  3LFY A;  1MIR A;  1AYU A;  3K8U A;  3ZNH A;  4YYV A;  3I3T A;  2VHF A;  1ATK A;  2FQ9 A;  4W5B A;  2JQF R;  3KWZ A;  4PI3 A;  3OVX A;  1CS8 A;  1MDW A;  2AUZ A;  1SNK A;  2NQI A;  2JQG R;  3V6C A;  4YYS A;  3RNV A;  1F2C A;  1CB5 A;  1TL9 A;  3KFQ A;  1ICF A;  2AYO A;  1NLJ A;  4QRV A;  4HXD B;  2NQA A;  3V6E A;  5KO3 A;  4BQV A;  1F2B A;  2YJ9 A;  4YVA A;  3CBJ A;  2DC9 A;  9PAP A;  1X9Y A;  1FH0 A;  1KFX L;  2AYN A;  3BC3 A;  1U9V A;  3BOW A;  2PRE A;  4QRX A;  5CHT A;  2H7J A;  2AU1 A;  4OVZ B;  2CB5 A;  3MJ5 A;  4YYU A;  5FPW A;  2HXZ A;  1EWP A;  1XKG A;  3KW9 A;  2XU3 A;  4N8W A;  4X6H A;  4RKX A;  1PAD A;  2O6X A;  4RF0 A;  1VSN A;  3N4C A;  2R9O A;  3WXE A;  1JQP A;  4PT5 A;  3O65 A;  2DC8 A;  2Z84 A;  2NQD B;  4AXL A;  1DEU A;  2R9C A;  3F5V A;  4BS5 A;  4BSQ A;  2R9F A;  5E6J A;  2IBI A;  3CBK A;  2Y5B A;  3QT4 A;  1CSB B;  3GCB A;  3BPM A;  4BOS A;  2BTW B;  1QOL A;  4W5C A;  2OUL A;  1CJL A;  4ZUX U;  2P7U A;  1PXV A;  3KX1 A;  2DZY A;  3P5V A;  2FUD A;  4D8I A;  2UZJ A;  4CDC B;  4PP1 A;  2PAD A;  2NQG A;  1SP4 B;  2DJF B;  1BGO A;  3KKU A;  4RY2 A;  2Y6E A;  1YK7 A;  2E01 A;  3ERV A;  1NB3 A;  5K16 A;  2YJB A;  4A5U A;  4XR7 A;  1POP A;  1U9X A;  2IPP B;  2B1N A;  5JH3 A;  2JRI A;  3IUT A;  1KXR A;  2FRA A;  4X6J A;  1NPZ A;  3RVV A;  3OF8 A;  1KHQ A;  3PRP A;  1O0E A;  3BY4 A;  2JTC A;  2BTW A;  2FT2 A;  1CTE A;  1MHW A;  2AUX A;  2R6N A;  1YZB A;  3U8E A;  4D8E A;  4YYR A;  4BOP A;  1THE A;  2P0R A;  8PCH A;  1YAL A;  4OEL A;  3LXS A;  3QJ3 A;  3HHA A;  4G54 A;  1F2A A;  4BOU A;  4FIP A;  4FK5 A;  1QXP A; 
#chains in the Genus database with same CATH homology
 3TNX A;  3H8B A;  3N3K A;  1VJV A;  3PDF A;  2FYE A;  3RVW A;  1MEM A;  3C9E A;  2HH5 A;  2DC7 A;  2F1G A;  2DCB A;  2DC6 A;  4DMY A;  1PPD A;  3BPF A;  3F75 A;  3WXF A;  3I06 A;  2G7Y A;  1Y4H A;  3O1G A;  1AU3 A;  3NHE A;  1EWL A;  1CPJ A;  3IOQ A;  1F29 A;  4YV8 A;  1BP4 A;  1AU4 A;  3P5W A;  4MZS A;  1CQD A;  4QRG A;  1PIP A;  2FO5 A;  3N3G A;  1AU2 A;  3OIS A;  4CDE B;  2CIO A;  1U5I A;  3BCN A;  5PAD A;  4C5P A;  3KSE A;  3QSD A;  4BPV A;  3H8C A;  4FJC A;  3RVX A;  5CVN B;  3M99 A;  4QH6 A;  4GUZ A;  1W6F A;  2GFO A;  5CHV A;  1MS6 A;  1PPP A;  2R9N A;  1QDQ A;  3LTW A;  4WA6 A;  4BS6 A;  4I07 A;  4Q8G A;  1NL6 A;  1HUC B;  1YK8 A;  3H7D A;  1KFU L;  4P6G A;  4Q8H A;  4N4Z A;  3WXG A;  1AYW A;  4QBB A;  1MEG A;  3O0U A;  2DCD A;  1IWD A;  1QMY A;  3D6S A;  2XU4 A;  7PCK A;  5J94 A;  1NB5 A;  4I04 A;  2C0Y A;  1Q6K A;  1AU0 A;  2BSZ A;  1PBH A;  1U9Q X;  2AVW A;  2BDL A;  3CH3 X;  3OF9 A;  1GLO A;  2DCC A;  2ATO A;  2G6D A;  5CVO B;  1KHP A;  3IV2 A;  3P5X A;  4MSX A;  2R9M A;  5EGW A;  1ME3 A;  4N79 A;  1EWO A;  3PW3 A;  4W4U A;  4AXM A;  3K24 A;  4XUI A;  4CDD B;  2AS8 A;  5F02 A;  4HWY A;  1CVZ A;  1DF0 A;  1M6D A;  2DCA A;  2GHU A;  1YT7 A;  1Y08 A;  1U9W A;  2G8E A;  1NQC A;  3K9M A;  3IEJ A;  1ZCM A;  3OVZ A;  3MTN A;  2B1M A;  2AIM A;  5EF4 A;  2PNS A;  1CV8 A;  1EF7 A;  1PCI A;  1AYV A;  2YJC A;  2VFB A;  3IMA A;  1ITO A;  3CH2 X;  2OP3 A;  3H89 A;  4X6I A;  2WBF X;  2ARY A;  2ACT A;  2DJG B;  2DZZ A;  3USV A;  3MOR A;  1AIM A;  4BGF A;  1TLO A;  1GMY A;  2E03 A;  3BWK A;  4YYQ A;  3IHP A;  3ZUA A;  3DF0 A;  2XU5 A;  4KLB A;  2E00 A;  5A24 A;  4MZO A;  2PBH A;  3H6S A;  3HWN A;  3MHH A;  4NV7 A;  6PAD A;  2VHS A;  3PBH A;  2F7D A;  4CDF B;  3S3Q A;  3MHS A;  4I05 A;  3S3R A;  4P6E A;  4DMX A;  1S4V A;  4OEM A;  1STF E;  4PAD A;  5CVM A;  2FRQ A;  2OZ2 A;  4PP2 E;  1K3B B;  1GEC E;  5JA7 A;  2XU1 A;  3HD3 A;  2G8J A;  1PPN A;  4YYW A;  1ZIV A;  1BY8 A;  1AEC A;  2P86 A;  1GCB A;  3B79 A;  1PE6 A;  2YJ8 A;  3AI8 A;  4K7C A;  3E1Z B;  1TU6 A;  2E02 A;  1PPO A;  1EWM A;  3KWB X;  2FTD A;  1A6R A;  3P5U A;  1YVB A;  1ME4 A;  3HHI A;  3PNR A;  2BDZ A;  2YJ2 A;  2HHN A;  4CZW A;  1BQI A;  2HD5 A;  3LFY A;  1MIR A;  1AYU A;  3K8U A;  4YYV A;  3I3T A;  2VHF A;  1ATK A;  2FQ9 A;  4W5B A;  2JQF R;  3KWZ A;  4PI3 A;  3OVX A;  1CS8 A;  1MDW A;  2AUZ A;  1SNK A;  2NQI A;  2JQG R;  3V6C A;  4NV8 A;  4YYS A;  1F2C A;  1CB5 A;  1TL9 A;  3KFQ A;  1ICF A;  2AYO A;  1NLJ A;  4QRV A;  2NQA A;  3V6E A;  4BQV A;  1F2B A;  2YJ9 A;  4YVA A;  3CBJ A;  2DC9 A;  9PAP A;  1X9Y A;  1FH0 A;  1KFX L;  2AYN A;  3BC3 A;  1U9V A;  3BOW A;  2PRE A;  4QRX A;  5CHT A;  2H7J A;  2AU1 A;  2CB5 A;  4YYU A;  5FPW A;  2HXZ A;  1EWP A;  2VFC A;  1XKG A;  3KW9 A;  2XU3 A;  4N8W A;  4X6H A;  1PAD A;  2O6X A;  1VSN A;  3N4C A;  2R9O A;  3WXE A;  1JQP A;  2DC8 A;  2NQD B;  4AXL A;  1DEU A;  2R9C A;  3F5V A;  4BS5 A;  4BSQ A;  2R9F A;  2IBI A;  3CBK A;  2Y5B A;  1E2T A;  3QT4 A;  1CSB B;  3D9W A;  3GCB A;  3BPM A;  1QOL A;  4W5C A;  2OUL A;  1W5R A;  1CJL A;  4ZUX U;  2P7U A;  1PXV A;  3KX1 A;  2DZY A;  3P5V A;  2FUD A;  4CDC B;  4PP1 A;  2PAD A;  2NQG A;  1SP4 B;  2DJF B;  1W4T A;  1BGO A;  3KKU A;  4RY2 A;  2Y6E A;  1YK7 A;  2E01 A;  3ERV A;  1NB3 A;  5K16 A;  2YJB A;  4XR7 A;  1POP A;  1U9X A;  2IPP B;  2B1N A;  5JH3 A;  3IUT A;  1KXR A;  2FRA A;  4X6J A;  1NPZ A;  3RVV A;  3OF8 A;  1KHQ A;  1O0E A;  4B55 A;  2FT2 A;  1CTE A;  1MHW A;  2AUX A;  2R6N A;  3U8E A;  4YYR A;  1THE A;  2P0R A;  8PCH A;  1YAL A;  4OEL A;  3LXS A;  1GX3 A;  3QJ3 A;  3HHA A;  4G54 A;  1F2A A;  4FIP A;  4FK5 A;  1QXP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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