1SNKA

Cathepsin k complexed with carbamate derivatized norleucine aldehyde
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
214
structure length
214
Chain Sequence
PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Exploration of the P(2)-P(3) SAR of aldehyde cathepsin K inhibitors
pubmed doi rcsb
molecule keywords Cathepsin K
molecule tags Hydrolase
source organism Homo sapiens
total genus 64
structure length 214
sequence length 214
ec nomenclature ec 3.4.22.38: Cathepsin K.
pdb deposition date 2004-03-11
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1snkA00
4K7CA 3PW3A 4W5CA 4BS6A 1KHQA 1TLOA 1EWPA 3M99A 1AU3A 1TL9A 2H7JA 2FRAA 3P5UA 4YYRA 1F29A 3BCNA 2AUZA 3IUTA 2B1MA 4OELA 2IPPB 1EWLA 2XU5A 3LFYA 3H89A 1GCBA 1QXPA 2AVWA 3HHAA 1AECA 4N8WA 5CVMA 4AXLA 1ITOA 1MS6A 3ERVA 3RVVA 1HUCB 4X6JA 3D6SA 2G8JA 2ATOA 2PREA 1QMYA 2OULA 2YJBA 3K9MA 4WA6A 3B79A 4DMXA 1CTEA 2DC6A 2BDLA 3F75A 5J94A 2FO5A 1BY8A 1CSBB 4PI3A 1U5IA 2AYNA 3MORA 3CH2X 2OP3A 2ARYA 1YT7A 1ZIVA 4I05A 1QDQA 1PADA 4W4UA 3HWNA 2CIOA 2ACTA 1AYWA 4AXMA 2NQGA 2FQ9A 3K24A 1F2AA 4MSXA 5F02A 3LXSA 1AYUA 5JH3A 1CV8A 3V6CA 5CHVA 3PBHA 1AU2A 2R9CA 1Y4HA 1PCIA 2YJ8A 1YALA 2FTDA 3CBJA 1AU0A 1FH0A 1K3BB 2R9NA 3RVXA 2VHFA 5A24A 5FPWA 1CQDA 2XU4A 3NHEA 1STFE 3IOQA 3N3KA 3H7DA 2NQIA 2CB5A 2AIMA 3C9EA 4CDDB 2DZZA 3CH3X 3KWZA 2NQDB 1MHWA 5CVOB 2DC8A 2PNSA 3O1GA 1KFXL 4YYQA 2FRQA 3K8UA 2FT2A 2AU1A 2IBIA 1ZCMA 1PXVA 3U8EA 6PADA 4G54A 4QRGA 1DF0A 3IMAA 3I06A 3BPMA 3PDFA 1NQCA 2P86A 3KWBX 1AYVA 3OF8A 1KXRA 1ME3A 3N3GA 4BSQA 5EGWA 4X6HA 4CDFB 3OVZA 4W5BA 2HHNA 2P7UA 2JQGR 3MHSA 2DCCA 2O6XA 1CVZA 2YJ9A 3P5VA 1KFUL 2G8EA 4CDEB 2XU1A 3N4CA 3QT4A 4Q8GA 2AS8A 1KHPA 4BQVA 2JQFR 2DJGB 3KKUA 4CDCB 1MIRA 5CHTA 2P0RA 4Q8HA 2FUDA 9PAPA 1PE6A 5EF4A 1BQIA 1S4VA 3QJ3A 4PP1A 3HD3A 1EWMA 1CS8A 1NPZA 3MHHA 3P5WA 4MZOA 4N79A 3H8CA 1F2CA 2F7DA 1GECE 3BOWA 3KSEA 3OF9A 3IV2A 4X6IA 2F1GA 1NLJA 1SP4B 3WXGA 1EF7A 4I04A 2BDZA 1GLOA 4I07A 4KLBA 4N4ZA 3TNXA 1IWDA 1TU6A 2NQAA 2C0YA 3P5XA 2DC9A 4FJCA 1CPJA 1PPNA 4HWYA 2E02A 2R9FA 1AIMA 4P6GA 3S3RA 3OVXA 4YYWA 4PADA 3E1ZB 4PP2E 3PNRA 3IEJA 1THEA 2DZYA 4OEMA 2E01A 1CJLA 4YYVA 4YVAA 1ICFA 1NL6A 3KFQA 1JQPA 2YJCA 1SNKA 1NB3A 1XKGA 2DC7A 1GMYA 3MTNA 2Y6EA 1U9QX 4QRXA 1CB5A 2DCDA 1BP4A 1X9YA 3OISA 1VJVA 2R9MA 1YK8A 5CVNB 1U9XA 2AYOA 2HH5A 2PBHA 3KW9A 3WXFA 4CZWA 4XUIA 1O0EA 3ZUAA 2FYEA 2R9OA 1ATKA 1YK7A 1AU4A 2DCBA 2HD5A 1PPOA 4BS5A 4QBBA 1EWOA 3DF0A 3S3QA 1F2BA 1POPA 3AI8A 4FIPA 2E03A 5K16A 4P6EA 2YJ2A 3BWKA 4YYSA 3F5VA 1Y08A 1Q6KA 1NB5A 2E00A 2AUXA 4MZSA 2PADA 1M6DA 2WBFX 4RY2A 5PADA 1MDWA 4YV8A 2HXZA 8PCHA 2VHSA 1MEGA 4XR7A 1PPPA 3H6SA 1PIPA 3IHPA 3HHIA 4DMYA 2G6DA 1VSNA 1A6RA 1ME4A 2Y5BA 3WXEA 1PPDA 4QH6A 1MEMA 7PCKA 3KX1A 3QSDA 2G7YA 3USVA 3V6EA 2R6NA 2XU3A 1BGOA 4YYUA 1U9WA 4FK5A 1QOLA 2OZ2A 5JA7A 3BC3A 2DJFB 3H8BA 3I3TA 4ZUXU 1DEUA 2B1NA 3O0UA 3CBKA 1PBHA 4BPVA 4QRVA 1U9VA 2DCAA 1YVBA 3RVWA 3GCBA 2GFOA 3BPFA 2GHUA
chains in the Genus database with same CATH superfamily
4K7CA 3PW3A 4W5CA 4XZXA 4BS6A 1KHQA 1TLOA 1EWPA 2AGAA 3M99A 1AU3A 1TL9A 2H7JA 2FRAA 3P5UA 4YYRA 1F29A 3BCNA 2AUZA 3IUTA 2B1MA 4OELA 2IPPB 1EWLA 2XU5A 3LFYA 3H89A 1GCBA 1QXPA 2AVWA 3HHAA 1AECA 4N8WA 4MI7A 5CVMA 4AXLA 1ITOA 1MS6A 3ERVA 3RVVA 1HUCB 4PT5A 4X6JA 3D6SA 2G8JA 2ATOA 2PREA 1QMYA 2OULA 2YJBA 3K9MA 4WA6A 3B79A 4DMXA 1CTEA 2DC6A 2BDLA 3F75A 5J94A 2FO5A 1BY8A 1CSBB 4OVZB 4IUMA 4PI3A 1U5IA 2AYNA 3MORA 3CH2X 2OP3A 2ARYA 1YT7A 1ZIVA 3BB7A 4I05A 1QDQA 1PADA 4W4UA 3HWNA 2Z84A 2CIOA 2ACTA 1AYWA 3MTVA 4AXMA 2NQGA 3RNVA 4BOSA 2FQ9A 4BOQA 3K24A 1F2AA 4MSXA 5F02A 3LXSA 1AYUA 5JH3A 1CV8A 3V6CA 5CHVA 3PBHA 1AU2A 3PHXA 2R9CA 1Y4HA 1PCIA 2DOSA 2YJ8A 2HWKA 3PRMA 1YALA 2FTDA 4ZTBA 3CBJA 1AU0A 1YZBA 1FH0A 1K3BB 2R9NA 3RVXA 2VHFA 5A24A 5FPWA 1CQDA 2XU4A 3NHEA 1STFE 4MM3B 3IOQA 3N3KA 3H7DA 2NQIA 2CB5A 2AIMA 3C9EA 4REZA 4CDDB 2DZZA 3CH3X 3KWZA 4RF1A 2NQDB 1MHWA 2JTCA 5CVOB 2DC8A 2PNSA 2JRIA 3O1GA 1KFXL 4YYQA 2FRQA 3K8UA 2FT2A 2BTWB 2AU1A 2IBIA 1ZCMA 1PXVA 3U8EA 6PADA 4G54A 4QRGA 1DF0A 3IMAA 3I06A 3BPMA 3PDFA 1NQCA 2P86A 3KWBX 1AYVA 3OF8A 1KXRA 1ME3A 3N3GA 4BSQA 5EGWA 4X6HA 4CDFB 3OVZA 3PRPA 4W5BA 3PHUA 2HHNA 2P7UA 2JQGR 3MHSA 2DCCA 3MP2A 2BTWA 2O6XA 1CVZA 1PVJA 2YJ9A 3P5VA 1KFUL 3PHWA 2G8EA 3OQCA 4CDEB 2XU1A 3N4CA 5KO3A 3QT4A 4Q8GA 2AS8A 1KHPA 3O65A 4BQVA 2JQFR 2DJGB 4WURA 4D8EA 3KKUA 4CDCB 1MIRA 5CHTA 4RNAA 2P0RA 4Q8HA 2FUDA 9PAPA 3TRKA 4GUAA 1PE6A 5EF4A 1BQIA 1S4VA 3QJ3A 4PP1A 3HD3A 4M0WA 1EWMA 1CS8A 1NPZA 3BBAA 3PT2A 3MHHA 3P5WA 4MZOA 3C0RA 4N79A 3E9SA 3H8CA 4RKXA 1F2CA 2FE8A 2F7DA 2J7QA 1GECE 3BOWA 3KSEA 3OF9A 4BOZA 3IV2A 4X6IA 2F1GA 1NLJA 1SP4B 3WXGA 1EF7A 4I04A 2BDZA 3IFUA 1GLOA 4I07A 4KLBA 4N4ZA 3TNXA 1IWDA 1TU6A 2NQAA 2C0YA 3P5XA 2DC9A 4FJCA 1CPJA 1PPNA 4HWYA 2E02A 2R9FA 1AIMA 4P6GA 3S3RA 4D8BA 3OVXA 4YYWA 4PADA 3E1ZB 4OW0A 4BOPA 4P16A 3PNRA 4PP2E 3IEJA 1THEA 2DZYA 4OEMA 2E01A 1CJLA 4YYVA 4YVAA 1ICFA 1NL6A 3KFQA 3BY4A 1JQPA 2YJCA 4HXDB 1SNKA 1NB3A 1XKGA 2DC7A 1GMYA 3MTNA 2Y6EA 1U9QX 4QRXA 1CB5A 2DCDA 1BP4A 1X9YA 3OISA 1VJVA 2R9MA 4D8IA 1YK8A 5CVNB 1U9XA 2AYOA 2HH5A 2PBHA 3KW9A 3W31A 3WXFA 4CZWA 4XUIA 1O0EA 3ZUAA 2BU3A 5EZSA 2FYEA 2R9OA 1ATKA 1YK7A 1AU4A 2DCBA 2HD5A 1PPOA 3ZNHA 4BS5A 4QBBA 5JZEA 1EWOA 3DF0A 3PSEA 3S3QA 1F2BA 1POPA 3AI8A 4FIPA 2E03A 3W30A 5K16A 4P6EA 1DKIA 5E6JA 2YJ2A 3BWKA 4YYSA 3F5VA 1Y08A 1Q6KA 4BOUA 1NB5A 2E00A 5EZQA 3B21A 2AUXA 4MZSA 2PADA 1M6DA 2WBFX 3MJ5A 4RY2A 5PADA 1MDWA 4YV8A 2HXZA 8PCHA 2VHSA 1MEGA 4XR7A 1PPPA 4RF0A 3H6SA 1PIPA 3IHPA 3HHIA 4DMYA 2G6DA 1VSNA 1A6RA 1ME4A 2Y5BA 3WXEA 1PPDA 4QH6A 1MEMA 4A5UA 7PCKA 2UZJA 3KX1A 3TMPA 3QSDA 2G7YA 1UKFA 3USVA 3V6EA 2R6NA 2XU3A 1BGOA 4YYUA 1U9WA 4R3DA 4OVZA 4FK5A 1QOLA 2OZ2A 5JA7A 3BC3A 2DJFB 3H8BA 3I3TA 4ZUXU 4IP3A 1DEUA 2B1NA 3O0UA 3CBKA 1PBHA 4BPVA 4QRVA 1U9VA 2DCAA 1YVBA 3RVWA 3GCBA 2GFOA 3BPFA 2J7QC 2GHUA
chains in the Genus database with same CATH topology
4K7CA 3PW3A 4W5CA 4BS6A 1KHQA 1TLOA 1EWPA 3M99A 1AU3A 1TL9A 2H7JA 2FRAA 3P5UA 4YYRA 1F29A 3BCNA 2AUZA 3IUTA 2B1MA 4OELA 2IPPB 1EWLA 2XU5A 3LFYA 3H89A 1GCBA 1QXPA 2AVWA 3HHAA 1AECA 4N8WA 5CVMA 4AXLA 1ITOA 1MS6A 3ERVA 3RVVA 1HUCB 4X6JA 3D6SA 2G8JA 2ATOA 2PREA 1QMYA 2OULA 2YJBA 3K9MA 4WA6A 3B79A 4DMXA 1CTEA 2DC6A 2BDLA 3F75A 5J94A 2FO5A 1BY8A 1CSBB 4PI3A 1U5IA 2AYNA 3MORA 3CH2X 2OP3A 2ARYA 1YT7A 1ZIVA 4I05A 1QDQA 1PADA 4BGFA 4W4UA 3HWNA 2CIOA 2ACTA 1AYWA 4AXMA 2NQGA 2FQ9A 3K24A 1F2AA 4MSXA 5F02A 3LXSA 1AYUA 5JH3A 1CV8A 3V6CA 3LTWA 5CHVA 3PBHA 1AU2A 2R9CA 1Y4HA 1PCIA 2YJ8A 1YALA 2FTDA 3CBJA 1AU0A 1FH0A 1K3BB 2R9NA 3RVXA 2VHFA 5A24A 5FPWA 1CQDA 2XU4A 3NHEA 1STFE 3IOQA 3N3KA 3H7DA 2NQIA 2CB5A 2AIMA 3C9EA 4CDDB 2DZZA 3CH3X 3KWZA 2NQDB 1MHWA 5CVOB 2DC8A 2PNSA 3O1GA 1KFXL 4YYQA 2FRQA 3K8UA 2FT2A 2AU1A 2IBIA 1ZCMA 1PXVA 3U8EA 6PADA 4G54A 4QRGA 1DF0A 3IMAA 3I06A 3BPMA 3PDFA 1NQCA 2P86A 3KWBX 1AYVA 3OF8A 1KXRA 1ME3A 3N3GA 4BSQA 5EGWA 4X6HA 4CDFB 3OVZA 4W5BA 2HHNA 2P7UA 2JQGR 3MHSA 2DCCA 2O6XA 1CVZA 2YJ9A 3P5VA 1KFUL 2G8EA 4CDEB 2XU1A 3N4CA 3QT4A 4Q8GA 2AS8A 4B55A 1KHPA 4BQVA 2JQFR 2DJGB 3KKUA 4CDCB 1MIRA 5CHTA 2P0RA 4Q8HA 2FUDA 9PAPA 4C5PA 1PE6A 5EF4A 1BQIA 1S4VA 3QJ3A 4PP1A 3HD3A 1EWMA 1CS8A 1NPZA 1GX3A 3MHHA 1W6FA 3P5WA 4MZOA 4N79A 3H8CA 1F2CA 2F7DA 1GECE 3BOWA 3KSEA 3OF9A 3IV2A 4X6IA 2F1GA 1NLJA 1SP4B 3WXGA 1EF7A 4I04A 2BDZA 1GLOA 4I07A 4KLBA 4N4ZA 3TNXA 1IWDA 1TU6A 2NQAA 2C0YA 3P5XA 2DC9A 4FJCA 1CPJA 1PPNA 4HWYA 1W4TA 2E02A 2R9FA 1AIMA 4P6GA 3S3RA 3OVXA 4YYWA 4PADA 3E1ZB 4PP2E 3PNRA 3IEJA 1THEA 2DZYA 4OEMA 2E01A 1CJLA 4YYVA 4YVAA 1ICFA 1NL6A 3KFQA 1JQPA 2YJCA 1SNKA 1NB3A 1XKGA 2DC7A 1GMYA 3MTNA 2Y6EA 1U9QX 4QRXA 1CB5A 2DCDA 1BP4A 1X9YA 3OISA 1VJVA 2R9MA 1YK8A 5CVNB 1U9XA 2AYOA 2HH5A 2PBHA 3KW9A 3WXFA 4CZWA 4XUIA 1O0EA 3ZUAA 2FYEA 2R9OA 1ATKA 1YK7A 1AU4A 2DCBA 2HD5A 1PPOA 4BS5A 4QBBA 1EWOA 1W5RA 3DF0A 3S3QA 1F2BA 1POPA 1E2TA 3AI8A 4FIPA 2E03A 5K16A 4P6EA 2YJ2A 3BWKA 4YYSA 3F5VA 1Y08A 1Q6KA 1NB5A 2E00A 2BSZA 2AUXA 4MZSA 2PADA 1M6DA 2WBFX 4RY2A 5PADA 1MDWA 4YV8A 2HXZA 8PCHA 2VHSA 1MEGA 4XR7A 1PPPA 3H6SA 1PIPA 2VFCA 3IHPA 3HHIA 4DMYA 2G6DA 4NV8A 1VSNA 1A6RA 1ME4A 2Y5BA 3WXEA 1PPDA 4QH6A 1MEMA 7PCKA 3D9WA 3KX1A 3QSDA 2G7YA 3USVA 3V6EA 2R6NA 2XU3A 1BGOA 4GUZA 4YYUA 1U9WA 4FK5A 1QOLA 2OZ2A 5JA7A 3BC3A 2DJFB 3H8BA 3I3TA 4ZUXU 1DEUA 2B1NA 3O0UA 3CBKA 1PBHA 4BPVA 4QRVA 1U9VA 2DCAA 2VFBA 1YVBA 3RVWA 3GCBA 2GFOA 3BPFA 4NV7A 2GHUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4K7C A;  3PW3 A;  4W5C A;  4BS6 A;  1KHQ A;  1TLO A;  1EWP A;  3M99 A;  1AU3 A;  1TL9 A;  2H7J A;  2FRA A;  3P5U A;  4YYR A;  1F29 A;  3BCN A;  2AUZ A;  3IUT A;  2B1M A;  4OEL A;  2IPP B;  1EWL A;  2XU5 A;  3LFY A;  3H89 A;  1GCB A;  1QXP A;  2AVW A;  3HHA A;  1AEC A;  4N8W A;  5CVM A;  4AXL A;  1ITO A;  1MS6 A;  3ERV A;  3RVV A;  1HUC B;  4X6J A;  3D6S A;  2G8J A;  2ATO A;  2PRE A;  1QMY A;  2OUL A;  2YJB A;  3K9M A;  4WA6 A;  3B79 A;  4DMX A;  1CTE A;  2DC6 A;  2BDL A;  3F75 A;  5J94 A;  2FO5 A;  1BY8 A;  1CSB B;  4PI3 A;  1U5I A;  2AYN A;  3MOR A;  3CH2 X;  2OP3 A;  2ARY A;  1YT7 A;  1ZIV A;  4I05 A;  1QDQ A;  1PAD A;  4W4U A;  3HWN A;  2CIO A;  2ACT A;  1AYW A;  4AXM A;  2NQG A;  2FQ9 A;  3K24 A;  1F2A A;  4MSX A;  5F02 A;  3LXS A;  1AYU A;  5JH3 A;  1CV8 A;  3V6C A;  5CHV A;  3PBH A;  1AU2 A;  2R9C A;  1Y4H A;  1PCI A;  2YJ8 A;  1YAL A;  2FTD A;  3CBJ A;  1AU0 A;  1FH0 A;  1K3B B;  2R9N A;  3RVX A;  2VHF A;  5A24 A;  5FPW A;  1CQD A;  2XU4 A;  3NHE A;  1STF E;  3IOQ A;  3N3K A;  3H7D A;  2NQI A;  2CB5 A;  2AIM A;  3C9E A;  4CDD B;  2DZZ A;  3CH3 X;  3KWZ A;  2NQD B;  1MHW A;  5CVO B;  2DC8 A;  2PNS A;  3O1G A;  1KFX L;  4YYQ A;  2FRQ A;  3K8U A;  2FT2 A;  2AU1 A;  2IBI A;  1ZCM A;  1PXV A;  3U8E A;  6PAD A;  4G54 A;  4QRG A;  1DF0 A;  3IMA A;  3I06 A;  3BPM A;  3PDF A;  1NQC A;  2P86 A;  3KWB X;  1AYV A;  3OF8 A;  1KXR A;  1ME3 A;  3N3G A;  4BSQ A;  5EGW A;  4X6H A;  4CDF B;  3OVZ A;  4W5B A;  2HHN A;  2P7U A;  2JQG R;  3MHS A;  2DCC A;  2O6X A;  1CVZ A;  2YJ9 A;  3P5V A;  1KFU L;  2G8E A;  4CDE B;  2XU1 A;  3N4C A;  3QT4 A;  4Q8G A;  2AS8 A;  1KHP A;  4BQV A;  2JQF R;  2DJG B;  3KKU A;  4CDC B;  1MIR A;  5CHT A;  2P0R A;  4Q8H A;  2FUD A;  9PAP A;  1PE6 A;  5EF4 A;  1BQI A;  1S4V A;  3QJ3 A;  4PP1 A;  3HD3 A;  1EWM A;  1CS8 A;  1NPZ A;  3MHH A;  3P5W A;  4MZO A;  4N79 A;  3H8C A;  1F2C A;  2F7D A;  1GEC E;  3BOW A;  3KSE A;  3OF9 A;  3IV2 A;  4X6I A;  2F1G A;  1NLJ A;  1SP4 B;  3WXG A;  1EF7 A;  4I04 A;  2BDZ A;  1GLO A;  4I07 A;  4KLB A;  4N4Z A;  3TNX A;  1IWD A;  1TU6 A;  2NQA A;  2C0Y A;  3P5X A;  2DC9 A;  4FJC A;  1CPJ A;  1PPN A;  4HWY A;  2E02 A;  2R9F A;  1AIM A;  4P6G A;  3S3R A;  3OVX A;  4YYW A;  4PAD A;  3E1Z B;  4PP2 E;  3PNR A;  3IEJ A;  1THE A;  2DZY A;  4OEM A;  2E01 A;  1CJL A;  4YYV A;  4YVA A;  1ICF A;  1NL6 A;  3KFQ A;  1JQP A;  2YJC A;  1SNK A;  1NB3 A;  1XKG A;  2DC7 A;  1GMY A;  3MTN A;  2Y6E A;  1U9Q X;  4QRX A;  1CB5 A;  2DCD A;  1BP4 A;  1X9Y A;  3OIS A;  1VJV A;  2R9M A;  1YK8 A;  5CVN B;  1U9X A;  2AYO A;  2HH5 A;  2PBH A;  3KW9 A;  3WXF A;  4CZW A;  4XUI A;  1O0E A;  3ZUA A;  2FYE A;  2R9O A;  1ATK A;  1YK7 A;  1AU4 A;  2DCB A;  2HD5 A;  1PPO A;  4BS5 A;  4QBB A;  1EWO A;  3DF0 A;  3S3Q A;  1F2B A;  1POP A;  3AI8 A;  4FIP A;  2E03 A;  5K16 A;  4P6E A;  2YJ2 A;  3BWK A;  4YYS A;  3F5V A;  1Y08 A;  1Q6K A;  1NB5 A;  2E00 A;  2AUX A;  4MZS A;  2PAD A;  1M6D A;  2WBF X;  4RY2 A;  5PAD A;  1MDW A;  4YV8 A;  2HXZ A;  8PCH A;  2VHS A;  1MEG A;  4XR7 A;  1PPP A;  3H6S A;  1PIP A;  3IHP A;  3HHI A;  4DMY A;  2G6D A;  1VSN A;  1A6R A;  1ME4 A;  2Y5B A;  3WXE A;  1PPD A;  4QH6 A;  1MEM A;  7PCK A;  3KX1 A;  3QSD A;  2G7Y A;  3USV A;  3V6E A;  2R6N A;  2XU3 A;  1BGO A;  4YYU A;  1U9W A;  4FK5 A;  1QOL A;  2OZ2 A;  5JA7 A;  3BC3 A;  2DJF B;  3H8B A;  3I3T A;  4ZUX U;  1DEU A;  2B1N A;  3O0U A;  3CBK A;  1PBH A;  4BPV A;  4QRV A;  1U9V A;  2DCA A;  1YVB A;  3RVW A;  3GCB A;  2GFO A;  3BPF A;  2GHU A; 
#chains in the Genus database with same CATH topology
 4K7C A;  3PW3 A;  4W5C A;  4XZX A;  4BS6 A;  1KHQ A;  1TLO A;  1EWP A;  2AGA A;  3M99 A;  1AU3 A;  1TL9 A;  2H7J A;  2FRA A;  3P5U A;  4YYR A;  1F29 A;  3BCN A;  2AUZ A;  3IUT A;  2B1M A;  4OEL A;  2IPP B;  1EWL A;  2XU5 A;  3LFY A;  3H89 A;  1GCB A;  1QXP A;  2AVW A;  3HHA A;  1AEC A;  4N8W A;  4MI7 A;  5CVM A;  4AXL A;  1ITO A;  1MS6 A;  3ERV A;  3RVV A;  1HUC B;  4PT5 A;  4X6J A;  3D6S A;  2G8J A;  2ATO A;  2PRE A;  1QMY A;  2OUL A;  2YJB A;  3K9M A;  4WA6 A;  3B79 A;  4DMX A;  1CTE A;  2DC6 A;  2BDL A;  3F75 A;  5J94 A;  2FO5 A;  1BY8 A;  1CSB B;  4OVZ B;  4IUM A;  4PI3 A;  1U5I A;  2AYN A;  3MOR A;  3CH2 X;  2OP3 A;  2ARY A;  1YT7 A;  1ZIV A;  3BB7 A;  4I05 A;  1QDQ A;  1PAD A;  4W4U A;  3HWN A;  2Z84 A;  2CIO A;  2ACT A;  1AYW A;  3MTV A;  4AXM A;  2NQG A;  3RNV A;  4BOS A;  2FQ9 A;  4BOQ A;  3K24 A;  1F2A A;  4MSX A;  5F02 A;  3LXS A;  1AYU A;  5JH3 A;  1CV8 A;  3V6C A;  5CHV A;  3PBH A;  1AU2 A;  3PHX A;  2R9C A;  1Y4H A;  1PCI A;  2DOS A;  2YJ8 A;  2HWK A;  3PRM A;  1YAL A;  2FTD A;  4ZTB A;  3CBJ A;  1AU0 A;  1YZB A;  1FH0 A;  1K3B B;  2R9N A;  3RVX A;  2VHF A;  5A24 A;  5FPW A;  1CQD A;  2XU4 A;  3NHE A;  1STF E;  4MM3 B;  3IOQ A;  3N3K A;  3H7D A;  2NQI A;  2CB5 A;  2AIM A;  3C9E A;  4REZ A;  4CDD B;  2DZZ A;  3CH3 X;  3KWZ A;  4RF1 A;  2NQD B;  1MHW A;  2JTC A;  5CVO B;  2DC8 A;  2PNS A;  2JRI A;  3O1G A;  1KFX L;  4YYQ A;  2FRQ A;  3K8U A;  2FT2 A;  2BTW B;  2AU1 A;  2IBI A;  1ZCM A;  1PXV A;  3U8E A;  6PAD A;  4G54 A;  4QRG A;  1DF0 A;  3IMA A;  3I06 A;  3BPM A;  3PDF A;  1NQC A;  2P86 A;  3KWB X;  1AYV A;  3OF8 A;  1KXR A;  1ME3 A;  3N3G A;  4BSQ A;  5EGW A;  4X6H A;  4CDF B;  3OVZ A;  3PRP A;  4W5B A;  3PHU A;  2HHN A;  2P7U A;  2JQG R;  3MHS A;  2DCC A;  3MP2 A;  2BTW A;  2O6X A;  1CVZ A;  1PVJ A;  2YJ9 A;  3P5V A;  1KFU L;  3PHW A;  2G8E A;  3OQC A;  4CDE B;  2XU1 A;  3N4C A;  5KO3 A;  3QT4 A;  4Q8G A;  2AS8 A;  1KHP A;  3O65 A;  4BQV A;  2JQF R;  2DJG B;  4WUR A;  4D8E A;  3KKU A;  4CDC B;  1MIR A;  5CHT A;  4RNA A;  2P0R A;  4Q8H A;  2FUD A;  9PAP A;  3TRK A;  4GUA A;  1PE6 A;  5EF4 A;  1BQI A;  1S4V A;  3QJ3 A;  4PP1 A;  3HD3 A;  4M0W A;  1EWM A;  1CS8 A;  1NPZ A;  3BBA A;  3PT2 A;  3MHH A;  3P5W A;  4MZO A;  3C0R A;  4N79 A;  3E9S A;  3H8C A;  4RKX A;  1F2C A;  2FE8 A;  2F7D A;  2J7Q A;  1GEC E;  3BOW A;  3KSE A;  3OF9 A;  4BOZ A;  3IV2 A;  4X6I A;  2F1G A;  1NLJ A;  1SP4 B;  3WXG A;  1EF7 A;  4I04 A;  2BDZ A;  3IFU A;  1GLO A;  4I07 A;  4KLB A;  4N4Z A;  3TNX A;  1IWD A;  1TU6 A;  2NQA A;  2C0Y A;  3P5X A;  2DC9 A;  4FJC A;  1CPJ A;  1PPN A;  4HWY A;  2E02 A;  2R9F A;  1AIM A;  4P6G A;  3S3R A;  4D8B A;  3OVX A;  4YYW A;  4PAD A;  3E1Z B;  4OW0 A;  4BOP A;  4P16 A;  3PNR A;  4PP2 E;  3IEJ A;  1THE A;  2DZY A;  4OEM A;  2E01 A;  1CJL A;  4YYV A;  4YVA A;  1ICF A;  1NL6 A;  3KFQ A;  3BY4 A;  1JQP A;  2YJC A;  4HXD B;  1SNK A;  1NB3 A;  1XKG A;  2DC7 A;  1GMY A;  3MTN A;  2Y6E A;  1U9Q X;  4QRX A;  1CB5 A;  2DCD A;  1BP4 A;  1X9Y A;  3OIS A;  1VJV A;  2R9M A;  4D8I A;  1YK8 A;  5CVN B;  1U9X A;  2AYO A;  2HH5 A;  2PBH A;  3KW9 A;  3W31 A;  3WXF A;  4CZW A;  4XUI A;  1O0E A;  3ZUA A;  2BU3 A;  5EZS A;  2FYE A;  2R9O A;  1ATK A;  1YK7 A;  1AU4 A;  2DCB A;  2HD5 A;  1PPO A;  3ZNH A;  4BS5 A;  4QBB A;  5JZE A;  1EWO A;  3DF0 A;  3PSE A;  3S3Q A;  1F2B A;  1POP A;  3AI8 A;  4FIP A;  2E03 A;  3W30 A;  5K16 A;  4P6E A;  1DKI A;  5E6J A;  2YJ2 A;  3BWK A;  4YYS A;  3F5V A;  1Y08 A;  1Q6K A;  4BOU A;  1NB5 A;  2E00 A;  5EZQ A;  3B21 A;  2AUX A;  4MZS A;  2PAD A;  1M6D A;  2WBF X;  3MJ5 A;  4RY2 A;  5PAD A;  1MDW A;  4YV8 A;  2HXZ A;  8PCH A;  2VHS A;  1MEG A;  4XR7 A;  1PPP A;  4RF0 A;  3H6S A;  1PIP A;  3IHP A;  3HHI A;  4DMY A;  2G6D A;  1VSN A;  1A6R A;  1ME4 A;  2Y5B A;  3WXE A;  1PPD A;  4QH6 A;  1MEM A;  4A5U A;  7PCK A;  2UZJ A;  3KX1 A;  3TMP A;  3QSD A;  2G7Y A;  1UKF A;  3USV A;  3V6E A;  2R6N A;  2XU3 A;  1BGO A;  4YYU A;  1U9W A;  4R3D A;  4OVZ A;  4FK5 A;  1QOL A;  2OZ2 A;  5JA7 A;  3BC3 A;  2DJF B;  3H8B A;  3I3T A;  4ZUX U;  4IP3 A;  1DEU A;  2B1N A;  3O0U A;  3CBK A;  1PBH A;  4BPV A;  4QRV A;  1U9V A;  2DCA A;  1YVB A;  3RVW A;  3GCB A;  2GFO A;  3BPF A;  2J7Q C;  2GHU A; 
#chains in the Genus database with same CATH homology
 4K7C A;  3PW3 A;  4W5C A;  4BS6 A;  1KHQ A;  1TLO A;  1EWP A;  3M99 A;  1AU3 A;  1TL9 A;  2H7J A;  2FRA A;  3P5U A;  4YYR A;  1F29 A;  3BCN A;  2AUZ A;  3IUT A;  2B1M A;  4OEL A;  2IPP B;  1EWL A;  2XU5 A;  3LFY A;  3H89 A;  1GCB A;  1QXP A;  2AVW A;  3HHA A;  1AEC A;  4N8W A;  5CVM A;  4AXL A;  1ITO A;  1MS6 A;  3ERV A;  3RVV A;  1HUC B;  4X6J A;  3D6S A;  2G8J A;  2ATO A;  2PRE A;  1QMY A;  2OUL A;  2YJB A;  3K9M A;  4WA6 A;  3B79 A;  4DMX A;  1CTE A;  2DC6 A;  2BDL A;  3F75 A;  5J94 A;  2FO5 A;  1BY8 A;  1CSB B;  4PI3 A;  1U5I A;  2AYN A;  3MOR A;  3CH2 X;  2OP3 A;  2ARY A;  1YT7 A;  1ZIV A;  4I05 A;  1QDQ A;  1PAD A;  4BGF A;  4W4U A;  3HWN A;  2CIO A;  2ACT A;  1AYW A;  4AXM A;  2NQG A;  2FQ9 A;  3K24 A;  1F2A A;  4MSX A;  5F02 A;  3LXS A;  1AYU A;  5JH3 A;  1CV8 A;  3V6C A;  3LTW A;  5CHV A;  3PBH A;  1AU2 A;  2R9C A;  1Y4H A;  1PCI A;  2YJ8 A;  1YAL A;  2FTD A;  3CBJ A;  1AU0 A;  1FH0 A;  1K3B B;  2R9N A;  3RVX A;  2VHF A;  5A24 A;  5FPW A;  1CQD A;  2XU4 A;  3NHE A;  1STF E;  3IOQ A;  3N3K A;  3H7D A;  2NQI A;  2CB5 A;  2AIM A;  3C9E A;  4CDD B;  2DZZ A;  3CH3 X;  3KWZ A;  2NQD B;  1MHW A;  5CVO B;  2DC8 A;  2PNS A;  3O1G A;  1KFX L;  4YYQ A;  2FRQ A;  3K8U A;  2FT2 A;  2AU1 A;  2IBI A;  1ZCM A;  1PXV A;  3U8E A;  6PAD A;  4G54 A;  4QRG A;  1DF0 A;  3IMA A;  3I06 A;  3BPM A;  3PDF A;  1NQC A;  2P86 A;  3KWB X;  1AYV A;  3OF8 A;  1KXR A;  1ME3 A;  3N3G A;  4BSQ A;  5EGW A;  4X6H A;  4CDF B;  3OVZ A;  4W5B A;  2HHN A;  2P7U A;  2JQG R;  3MHS A;  2DCC A;  2O6X A;  1CVZ A;  2YJ9 A;  3P5V A;  1KFU L;  2G8E A;  4CDE B;  2XU1 A;  3N4C A;  3QT4 A;  4Q8G A;  2AS8 A;  4B55 A;  1KHP A;  4BQV A;  2JQF R;  2DJG B;  3KKU A;  4CDC B;  1MIR A;  5CHT A;  2P0R A;  4Q8H A;  2FUD A;  9PAP A;  4C5P A;  1PE6 A;  5EF4 A;  1BQI A;  1S4V A;  3QJ3 A;  4PP1 A;  3HD3 A;  1EWM A;  1CS8 A;  1NPZ A;  1GX3 A;  3MHH A;  1W6F A;  3P5W A;  4MZO A;  4N79 A;  3H8C A;  1F2C A;  2F7D A;  1GEC E;  3BOW A;  3KSE A;  3OF9 A;  3IV2 A;  4X6I A;  2F1G A;  1NLJ A;  1SP4 B;  3WXG A;  1EF7 A;  4I04 A;  2BDZ A;  1GLO A;  4I07 A;  4KLB A;  4N4Z A;  3TNX A;  1IWD A;  1TU6 A;  2NQA A;  2C0Y A;  3P5X A;  2DC9 A;  4FJC A;  1CPJ A;  1PPN A;  4HWY A;  1W4T A;  2E02 A;  2R9F A;  1AIM A;  4P6G A;  3S3R A;  3OVX A;  4YYW A;  4PAD A;  3E1Z B;  4PP2 E;  3PNR A;  3IEJ A;  1THE A;  2DZY A;  4OEM A;  2E01 A;  1CJL A;  4YYV A;  4YVA A;  1ICF A;  1NL6 A;  3KFQ A;  1JQP A;  2YJC A;  1SNK A;  1NB3 A;  1XKG A;  2DC7 A;  1GMY A;  3MTN A;  2Y6E A;  1U9Q X;  4QRX A;  1CB5 A;  2DCD A;  1BP4 A;  1X9Y A;  3OIS A;  1VJV A;  2R9M A;  1YK8 A;  5CVN B;  1U9X A;  2AYO A;  2HH5 A;  2PBH A;  3KW9 A;  3WXF A;  4CZW A;  4XUI A;  1O0E A;  3ZUA A;  2FYE A;  2R9O A;  1ATK A;  1YK7 A;  1AU4 A;  2DCB A;  2HD5 A;  1PPO A;  4BS5 A;  4QBB A;  1EWO A;  1W5R A;  3DF0 A;  3S3Q A;  1F2B A;  1POP A;  1E2T A;  3AI8 A;  4FIP A;  2E03 A;  5K16 A;  4P6E A;  2YJ2 A;  3BWK A;  4YYS A;  3F5V A;  1Y08 A;  1Q6K A;  1NB5 A;  2E00 A;  2BSZ A;  2AUX A;  4MZS A;  2PAD A;  1M6D A;  2WBF X;  4RY2 A;  5PAD A;  1MDW A;  4YV8 A;  2HXZ A;  8PCH A;  2VHS A;  1MEG A;  4XR7 A;  1PPP A;  3H6S A;  1PIP A;  2VFC A;  3IHP A;  3HHI A;  4DMY A;  2G6D A;  4NV8 A;  1VSN A;  1A6R A;  1ME4 A;  2Y5B A;  3WXE A;  1PPD A;  4QH6 A;  1MEM A;  7PCK A;  3D9W A;  3KX1 A;  3QSD A;  2G7Y A;  3USV A;  3V6E A;  2R6N A;  2XU3 A;  1BGO A;  4GUZ A;  4YYU A;  1U9W A;  4FK5 A;  1QOL A;  2OZ2 A;  5JA7 A;  3BC3 A;  2DJF B;  3H8B A;  3I3T A;  4ZUX U;  1DEU A;  2B1N A;  3O0U A;  3CBK A;  1PBH A;  4BPV A;  4QRV A;  1U9V A;  2DCA A;  2VFB A;  1YVB A;  3RVW A;  3GCB A;  2GFO A;  3BPF A;  4NV7 A;  2GHU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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