1PVJA

Crystal structure of the streptococcal pyrogenic exotoxin b (speb)- inhibitor complex
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
368
structure length
339
Chain Sequence
b'FARNEKEAKDSAITFIQKIKLDKVNLGGELSGSNMYVYNISTGGFVIVSGDKRSPEILGYSTSGSFDANGKENIASFMESYVEQIKENKKLDTTYAQPVVKSLLDSKGIHYNQGNPYNLLTPVIEKVKPGEQSFVGQHAATGCVATATAQIMKYHNYPNKGLKDYTYTLSSNNPYFNHPKNLFAAISTRQYNWNNILPTYSGRESNVQKMAISELMADVGISVDMDYGPSSGSAGSSRVQRALKENFGYNQSVHQINRGDFSKQDWEAQIDKELSQNQPVYYQGVGKVGGHAFVIDGADGRNFYHVNWGWGGVSDGFFRLDALNPGFNGYQSAVVGIKP'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords pyrogenic exotoxin B
publication title Inhibition of autoprocessing of the streptococcal pyrogenic exotoxin B (speB). Crystal structure of the proenzyme-inhibitor complex
rcsb
molecule tags Toxin
total genus 105
structure length 339
sequence length 368
chains with identical sequence B, C, D
ec nomenclature ec 3.4.22.10: Streptopain.
pdb deposition date 2003-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01640 Peptidase_C10 Peptidase C10 family
A PF13734 Inhibitor_I69 Spi protease inhibitor
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.910.30 Alpha Beta 2-Layer Sandwich Protein Binding, DinI Protein; Chain A Protein Binding, DinI Protein; Chain A 1pvjA02
3.90.70.50 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cathepsin B; Chain A 1pvjA01
4RKXA 3BB7A 3BBAA 4D8BA 2UZJA 4D8IA 2JTCA 1DKIA 1PVJA 4D8EA
chains in the Genus database with same CATH superfamily
3PBHA 2HH5A 3USVA 1O0EA 4P6EA 1YT7A 2FE8A 1KHQA 2FT2A 2E01A 1HUCB 2BTWB 3M99A 2OP3A 2FYEA 4I05A 4CDFB 4QRGA 2B1MA 4N79A 4CZWA 1ICFA 3BPFA 3D6SA 3OVZA 2YJ9A 4AXLA 2NQIA 3F5VA 4BOUA 1AU4A 2GHUA 2YJBA 1AU0A 3H6SA 1Y08A 4YYQA 1MS6A 2J7QA 2AUXA 3TMPA 2DOSA 2BDZA 1KHPA 2BTWA 3F75A 2R9FA 2O6XA 3PRPA 4YYVA 1F29A 5PADA 1MDWA 4MZSA 3WXFA 1QMYA 3CBKA 4YV8A 3E1ZB 2ACTA 4HXDB 1EF7A 3U8EA 3H8CA 3PHWA 3BBAA 3IFUA 4HWYA 5CVNB 2DC7A 2AU1A 1U9XA 3I06A 1BY8A 1ZIVA 2JQFR 2CB5A 4REZA 2AVWA 3O0UA 3P5UA 1PXVA 2Y6EA 4OEMA 3H8BA 1KFXL 4RF0A 1POPA 4PI3A 1A6RA 2VHFA 4K7CA 4FIPA 3HD3A 1MEGA 2J7QC 5FPWA 1GLOA 2R9MA 2R9CA 4IUMA 2IPPB 2XU1A 2NQAA 1CPJA 2G8EA 3H7DA 1AIMA 2AYNA 1TLOA 1F2AA 1S4VA 2FRAA 4Q8GA 3HHIA 3V6EA 5K16A 1CSBB 1NQCA 2AYOA 1Q6KA 4ZTBA 4XUIA 3MP2A 1U9WA 5J94A 4DMYA 1KXRA 4RKXA 1PPOA 9PAPA 1AECA 3C9EA 1UKFA 4ZUXU 2HXZA 1ITOA 3QJ3A 3KWBX 4BQVA 3WXEA 2G7YA 4GUAA 1AU3A 1BQIA 1NPZA 1AYUA 1VJVA 5KO3A 1ATKA 4XZXA 3TRKA 4N8WA 1CJLA 3N3GA 3E9SA 1ZCMA 3PNRA 2AS8A 2E02A 1THEA 2FUDA 7PCKA 2G6DA 2AGAA 3K24A 1AU2A 4G54A 1QXPA 1TL9A 3PW3A 3S3RA 3TNXA 2BDLA 1U5IA 4RF1A 1CV8A 2OZ2A 4M0WA 4DMXA 4MZOA 3W30A 3H89A 1DKIA 2HWKA 5A24A 3B79A 4OELA 2Z84A 1U2MA 4EVXA 4QBBA 3PRMA 2CIOA 1MIRA 1PPPA 4BPVA 3I3TA 1YVBA 8PCHA 1PVJA 4BOPA 2HHNA 4WURA 1BP4A 2XU3A 3OISA 1GHHA 5CVOB 1M6DA 2PREA 2E03A 4W5BA 4BS5A 2PADA 3KWZA 2FO5A 2F1GA 2FQ9A 2DCBA 1CS8A 2C0YA 1QDQA 2NQGA 5JZEA 2AIMA 4RY2A 1K3BB 4QH6A 2FTDA 4W5CA 4MI7A 2E00A 2GFOA 4PP1A 2R6NA 1STFE 3ZUAA 1KFUL 3K8UA 4P16A 3PDFA 1GCBA 2DC8A 2YJ8A 1MHWA 3OQCA 1EWLA 4QRXA 3WXGA 4MSXA 3MTNA 4OW0A 1NL6A 3W31A 5JA7A 3RVWA 2H7JA 6PADA 2Y5BA 5EGWA 4PT5A 3CH3X 1ME4A 2F7DA 1YALA 2WBFX 1FH0A 5CHVA 3BOWA 3CBJA 3P5VA 5CVMA 4MM3B 4YVAA 1GMYA 3DF0A 3MHHA 2B1NA 3N4CA 3PHUA 5JH3A 4WA6A 4I04A 4PADA 3GCBA 2JRIA 2JQGR 1F2BA 4W4UA 2YJ2A 4YYRA 3PHXA 3BC3A 1AYVA 2ATOA 3BPMA 3V6CA 2PBHA 3KX1A 3RNVA 2DCAA 3BY4A 4YYUA 1PPDA 2NQDB 4BOQA 3AI8A 3BWKA 3RVVA 3P5WA 1SG2A 4KQTA 1X9YA 2XU4A 3HWNA 3OF9A 3IUTA 3IV2A 1BGOA 2ARYA 5F02A 4X6JA 4N4ZA 2P7UA 2IBIA 1YZBA 4Q8HA 4CDCB 1PPNA 2YJCA 3IMAA 2R9NA 4P6GA 1SP4B 3S3QA 3KKUA 1DEUA 3QT4A 1PE6A 1U9VA 3ERVA 1F2CA 3O1GA 4FJCA 4OVZB 1CTEA 2OULA 3BB7A 2P86A 1MEMA 1EWMA 2DC6A 1EWPA 1JQPA 2FRQA 4KLBA 3RVXA 3N3KA 3HHAA 2DZYA 4D8EA 2P0RA 3MHSA 4BS6A 2HD5A 3K9MA 1PADA 4D8IA 3KW9A 3QSDA 4OVZA 4FK5A 4X6HA 3NHEA 1PBHA 1EWOA 3IOQA 4I07A 2DCCA 2BU3A 1PIPA 3PSEA 4XR7A 2DC9A 2PNSA 4A5UA 1SNKA 4D8BA 2DJFB 3LFYA 1U9QX 1XKGA 4CDDB 3B21A 4BOSA 1NLJA 2XU5A 5EZQA 3P5XA 5EF4A 4X6IA 3MORA 1YK7A 3OVXA 3KSEA 1YK8A 3PT2A 1Y4HA 1CB5A 1ME3A 2AUZA 3IEJA 4BOZA 4CDEB 4R3DA 1GECE 5EZSA 4AXMA 5CHTA 2R9OA 4QRVA 2G8JA 2VHSA 4YYWA 1QOLA 1NB5A 1TU6A 1NB3A 4BSQA 1VSNA 1CVZA 3LXSA 3MTVA 3IHPA 3CH2X 3MJ5A 2DJGB 1IWDA 4RNAA 2DZZA 4YYSA 4IP3A 2DCDA 1PCIA 3OF8A 3BCNA 5E6JA 1CQDA 3C0RA 1AYWA 4PP2E 1DF0A 3O65A 3ZNHA 2UZJA 2JTCA 3KFQA
chains in the Genus database with same CATH topology
3BB7A 2FE8A 4RKXA 4P16A 1UKFA 3OQCA 2BTWB 4D8EA 4OW0A 4GUAA 4D8IA 4OVZA 3W31A 5KO3A 4BOUA 4XZXA 3TRKA 2BU3A 2J7QA 3PSEA 4PT5A 3TMPA 2DOSA 3E9SA 2BTWA 4A5UA 3PRPA 4D8BA 2AGAA 3B21A 4MM3B 4BOSA 5EZQA 3PHUA 4RF1A 4M0WA 4HXDB 2JRIA 3W30A 1DKIA 2HWKA 3PT2A 3PHWA 3BBAA 3IFUA 3PHXA 3RNVA 3BY4A 2Z84A 4REZA 4BOZA 4BOQA 4R3DA 4EVXA 5EZSA 3PRMA 4RF0A 1PVJA 4BOPA 4WURA 2J7QC 4IUMA 3MTVA 3MJ5A 1YZBA 4RNAA 4IP3A 5JZEA 5E6JA 3C0RA 4MI7A 3O65A 3ZNHA 4ZTBA 2UZJA 3MP2A 2JTCA 4OVZB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RKX A;  3BB7 A;  3BBA A;  4D8B A;  2UZJ A;  4D8I A;  2JTC A;  1DKI A;  1PVJ A;  4D8E A; 
#chains in the Genus database with same CATH topology
 3PBH A;  2HH5 A;  3USV A;  1O0E A;  4P6E A;  1YT7 A;  2FE8 A;  1KHQ A;  2FT2 A;  2E01 A;  1HUC B;  2BTW B;  3M99 A;  2OP3 A;  2FYE A;  4I05 A;  4CDF B;  4QRG A;  2B1M A;  4N79 A;  4CZW A;  1ICF A;  3BPF A;  3D6S A;  3OVZ A;  2YJ9 A;  4AXL A;  2NQI A;  3F5V A;  4BOU A;  1AU4 A;  2GHU A;  2YJB A;  1AU0 A;  3H6S A;  1Y08 A;  4YYQ A;  1MS6 A;  2J7Q A;  2AUX A;  3TMP A;  2DOS A;  2BDZ A;  1KHP A;  2BTW A;  3F75 A;  2R9F A;  2O6X A;  3PRP A;  4YYV A;  1F29 A;  5PAD A;  1MDW A;  4MZS A;  3WXF A;  1QMY A;  3CBK A;  4YV8 A;  3E1Z B;  2ACT A;  4HXD B;  1EF7 A;  3U8E A;  3H8C A;  3PHW A;  3BBA A;  3IFU A;  4HWY A;  5CVN B;  2DC7 A;  2AU1 A;  1U9X A;  3I06 A;  1BY8 A;  1ZIV A;  2JQF R;  2CB5 A;  4REZ A;  2AVW A;  3O0U A;  3P5U A;  1PXV A;  2Y6E A;  4OEM A;  3H8B A;  1KFX L;  4RF0 A;  1POP A;  4PI3 A;  1A6R A;  2VHF A;  4K7C A;  4FIP A;  3HD3 A;  1MEG A;  2J7Q C;  5FPW A;  1GLO A;  2R9M A;  2R9C A;  4IUM A;  2IPP B;  2XU1 A;  2NQA A;  1CPJ A;  2G8E A;  3H7D A;  1AIM A;  2AYN A;  1TLO A;  1F2A A;  1S4V A;  2FRA A;  4Q8G A;  3HHI A;  3V6E A;  5K16 A;  1CSB B;  1NQC A;  2AYO A;  1Q6K A;  4ZTB A;  4XUI A;  3MP2 A;  1U9W A;  5J94 A;  4DMY A;  1KXR A;  4RKX A;  1PPO A;  9PAP A;  1AEC A;  3C9E A;  1UKF A;  4ZUX U;  2HXZ A;  1ITO A;  3QJ3 A;  3KWB X;  4BQV A;  3WXE A;  2G7Y A;  4GUA A;  1AU3 A;  1BQI A;  1NPZ A;  1AYU A;  1VJV A;  5KO3 A;  1ATK A;  4XZX A;  3TRK A;  4N8W A;  1CJL A;  3N3G A;  3E9S A;  1ZCM A;  3PNR A;  2AS8 A;  2E02 A;  1THE A;  2FUD A;  7PCK A;  2G6D A;  2AGA A;  3K24 A;  1AU2 A;  4G54 A;  1QXP A;  1TL9 A;  3PW3 A;  3S3R A;  3TNX A;  2BDL A;  1U5I A;  4RF1 A;  1CV8 A;  2OZ2 A;  4M0W A;  4DMX A;  4MZO A;  3W30 A;  3H89 A;  1DKI A;  2HWK A;  5A24 A;  3B79 A;  4OEL A;  2Z84 A;  1U2M A;  4EVX A;  4QBB A;  3PRM A;  2CIO A;  1MIR A;  1PPP A;  4BPV A;  3I3T A;  1YVB A;  8PCH A;  1PVJ A;  4BOP A;  2HHN A;  4WUR A;  1BP4 A;  2XU3 A;  3OIS A;  1GHH A;  5CVO B;  1M6D A;  2PRE A;  2E03 A;  4W5B A;  4BS5 A;  2PAD A;  3KWZ A;  2FO5 A;  2F1G A;  2FQ9 A;  2DCB A;  1CS8 A;  2C0Y A;  1QDQ A;  2NQG A;  5JZE A;  2AIM A;  4RY2 A;  1K3B B;  4QH6 A;  2FTD A;  4W5C A;  4MI7 A;  2E00 A;  2GFO A;  4PP1 A;  2R6N A;  1STF E;  3ZUA A;  1KFU L;  3K8U A;  4P16 A;  3PDF A;  1GCB A;  2DC8 A;  2YJ8 A;  1MHW A;  3OQC A;  1EWL A;  4QRX A;  3WXG A;  4MSX A;  3MTN A;  4OW0 A;  1NL6 A;  3W31 A;  5JA7 A;  3RVW A;  2H7J A;  6PAD A;  2Y5B A;  5EGW A;  4PT5 A;  3CH3 X;  1ME4 A;  2F7D A;  1YAL A;  2WBF X;  1FH0 A;  5CHV A;  3BOW A;  3CBJ A;  3P5V A;  5CVM A;  4MM3 B;  4YVA A;  1GMY A;  3DF0 A;  3MHH A;  2B1N A;  3N4C A;  3PHU A;  5JH3 A;  4WA6 A;  4I04 A;  4PAD A;  3GCB A;  2JRI A;  2JQG R;  1F2B A;  4W4U A;  2YJ2 A;  4YYR A;  3PHX A;  3BC3 A;  1AYV A;  2ATO A;  3BPM A;  3V6C A;  2PBH A;  3KX1 A;  3RNV A;  2DCA A;  3BY4 A;  4YYU A;  1PPD A;  2NQD B;  4BOQ A;  3AI8 A;  3BWK A;  3RVV A;  3P5W A;  1SG2 A;  4KQT A;  1X9Y A;  2XU4 A;  3HWN A;  3OF9 A;  3IUT A;  3IV2 A;  1BGO A;  2ARY A;  5F02 A;  4X6J A;  4N4Z A;  2P7U A;  2IBI A;  1YZB A;  4Q8H A;  4CDC B;  1PPN A;  2YJC A;  3IMA A;  2R9N A;  4P6G A;  1SP4 B;  3S3Q A;  3KKU A;  1DEU A;  3QT4 A;  1PE6 A;  1U9V A;  3ERV A;  1F2C A;  3O1G A;  4FJC A;  4OVZ B;  1CTE A;  2OUL A;  3BB7 A;  2P86 A;  1MEM A;  1EWM A;  2DC6 A;  1EWP A;  1JQP A;  2FRQ A;  4KLB A;  3RVX A;  3N3K A;  3HHA A;  2DZY A;  4D8E A;  2P0R A;  3MHS A;  4BS6 A;  2HD5 A;  3K9M A;  1PAD A;  4D8I A;  3KW9 A;  3QSD A;  4OVZ A;  4FK5 A;  4X6H A;  3NHE A;  1PBH A;  1EWO A;  3IOQ A;  4I07 A;  2DCC A;  2BU3 A;  1PIP A;  3PSE A;  4XR7 A;  2DC9 A;  2PNS A;  4A5U A;  1SNK A;  4D8B A;  2DJF B;  3LFY A;  1U9Q X;  1XKG A;  4CDD B;  3B21 A;  4BOS A;  1NLJ A;  2XU5 A;  5EZQ A;  3P5X A;  5EF4 A;  4X6I A;  3MOR A;  1YK7 A;  3OVX A;  3KSE A;  1YK8 A;  3PT2 A;  1Y4H A;  1CB5 A;  1ME3 A;  2AUZ A;  3IEJ A;  4BOZ A;  4CDE B;  4R3D A;  1GEC E;  5EZS A;  4AXM A;  5CHT A;  2R9O A;  4QRV A;  2G8J A;  2VHS A;  4YYW A;  1QOL A;  1NB5 A;  1TU6 A;  1NB3 A;  4BSQ A;  1VSN A;  1CVZ A;  3LXS A;  3MTV A;  3IHP A;  3CH2 X;  3MJ5 A;  2DJG B;  1IWD A;  4RNA A;  2DZZ A;  4YYS A;  4IP3 A;  2DCD A;  1PCI A;  3OF8 A;  3BCN A;  5E6J A;  1CQD A;  3C0R A;  1AYW A;  4PP2 E;  1DF0 A;  3O65 A;  3ZNH A;  2UZJ A;  2JTC A;  3KFQ A; 
#chains in the Genus database with same CATH homology
 3BB7 A;  2FE8 A;  4RKX A;  4P16 A;  1UKF A;  3OQC A;  2BTW B;  4D8E A;  4OW0 A;  4GUA A;  4D8I A;  4OVZ A;  3W31 A;  5KO3 A;  4BOU A;  4XZX A;  3TRK A;  2BU3 A;  2J7Q A;  3PSE A;  4PT5 A;  3TMP A;  2DOS A;  3E9S A;  2BTW A;  4A5U A;  3PRP A;  4D8B A;  2AGA A;  3B21 A;  4MM3 B;  4BOS A;  5EZQ A;  3PHU A;  4RF1 A;  4M0W A;  4HXD B;  2JRI A;  3W30 A;  1DKI A;  2HWK A;  3PT2 A;  3PHW A;  3BBA A;  3IFU A;  3PHX A;  3RNV A;  3BY4 A;  2Z84 A;  4REZ A;  4BOZ A;  4BOQ A;  4R3D A;  4EVX A;  5EZS A;  3PRM A;  4RF0 A;  1PVJ A;  4BOP A;  4WUR A;  2J7Q C;  4IUM A;  3MTV A;  3MJ5 A;  1YZB A;  4RNA A;  4IP3 A;  5JZE A;  5E6J A;  3C0R A;  4MI7 A;  3O65 A;  3ZNH A;  4ZTB A;  2UZJ A;  3MP2 A;  2JTC A;  4OVZ B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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