3MP2A

Crystal structure of transmissible gastroenteritis virus papain-like protease 1
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
211
structure length
211
Chain Sequence
SLPPFKTTNLNGKIILKQGDNNCWINACCYQLQAFDFFNNEAWEKFKKGDVMDFVNLCYAATTLARGHSGDAEYLLELMLNDYSTAKIVLAAKCGCGEKEIVLERAVFKLTPLKESFNYGVCGDCMQVNTCRFLSVEGSGVFVHDILSKQTPEAMFVVKPVMHAVYTGTTQNGHYMVDDIEHGYCVDGMGIKPLKKRCYTSTLFINANVMT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Papain-Like Protease 1 from Transmissible Gastroenteritis Virus: Crystal Structure and Enzymatic Activity toward Viral and Cellular Substrates.
pubmed doi rcsb
molecule tags Hydrolase
source organism Porcine transmissible gastroenteritis coronavirus
molecule keywords Non-structural protein 3
total genus 49
structure length 211
sequence length 211
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 2010-04-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.90 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cathepsin B; Chain A 3mp2A00
3MP2A 2FE8A 4OVZB 4RF0A 4M0WA 4WURA 4P16A 4R3DA 4REZA 4PT5A 3E9SA 4MM3B 5E6JA 5KO3A 4OW0A 4OVZA 4RNAA 3MJ5A 4RF1A
chains in the Genus database with same CATH superfamily
2NQDB 2DC7A 2HXZA 1EWLA 4D8EA 4FIPA 3IMAA 4RF0A 2AYOA 1PCIA 2DOSA 4IP3A 1CPJA 5JA7A 1AYVA 1M6DA 4W5BA 2B1NA 3D6SA 5CHVA 5E6JA 1PBHA 1U9WA 4P6GA 2BDLA 1PADA 4BQVA 2PADA 4N8WA 3CH2X 2R9OA 2YJ2A 3OISA 4QRXA 2E01A 2Y6EA 4HXDB 3OF8A 2OZ2A 2AVWA 3IEJA 4DMYA 4MZOA 3B21A 1POPA 1IWDA 2Y5BA 3S3QA 4OW0A 5A24A 2NQGA 1TL9A 1CVZA 3IFUA 4QRGA 4BS5A 3PHXA 3PDFA 1GMYA 3OVZA 2H7JA 1O0EA 3OVXA 2JTCA 3F5VA 4OELA 1AU0A 4HWYA 2HH5A 4N79A 5EZQA 1EWOA 4QBBA 1NQCA 1GCBA 3PHUA 3HWNA 9PAPA 4WA6A 1AIMA 2R9CA 3MORA 2R9MA 4PADA 4OVZB 4QRVA 2G8JA 3KWBX 2VHSA 2E02A 3C0RA 1BQIA 1ZCMA 2FTDA 2CIOA 4MI7A 1KHPA 3I06A 1ZIVA 3K9MA 3CBKA 3PNRA 3NHEA 4YYRA 1MS6A 5JZEA 3S3RA 1XKGA 4BSQA 4YYSA 2AUZA 1YK7A 1ME4A 1QXPA 2DCAA 2FRAA 4M0WA 4X6JA 1VJVA 3HHAA 2UZJA 2AGAA 4BOPA 7PCKA 1YALA 1SP4B 5EZSA 5JH3A 1GLOA 1TU6A 3IOQA 2AIMA 4AXMA 2YJBA 1MDWA 3W30A 1BY8A 1PE6A 1AU4A 2DJFB 2E00A 1JQPA 2P7UA 2DC9A 3CBJA 3BB7A 3PHWA 3CH3X 1STFE 5CHTA 1AU2A 1F2CA 4D8IA 1KFXL 4ZTBA 2AS8A 3BWKA 4PT5A 3BPMA 4W5CA 4KLBA 4RKXA 2J7QA 3PSEA 3F75A 1NPZA 3H89A 2CB5A 1YK8A 4GUAA 2DZZA 2FRQA 1X9YA 4YYWA 3KSEA 3ERVA 3TMPA 3KX1A 4YV8A 4ZUXU 3IUTA 5K16A 2PNSA 2E03A 2F7DA 1ITOA 3BCNA 3ZUAA 2JRIA 4MZSA 4BPVA 3RNVA 3OQCA 3O1GA 1UKFA 3W31A 1PIPA 3MTNA 2J7QC 2G8EA 1U9QX 2BTWA 2DC8A 3P5VA 2NQAA 4FJCA 2WBFX 3LXSA 3V6CA 2FUDA 1AYWA 1EF7A 4P6EA 1THEA 4X6HA 3V6EA 3TRKA 4A5UA 3M99A 2PBHA 3PT2A 2YJCA 4RNAA 3RVWA 3MHSA 2FE8A 3IHPA 3N4CA 1YT7A 2DCDA 1DEUA 1QDQA 3BBAA 5PADA 1DF0A 4R3DA 3QJ3A 4OEMA 4CDDB 1YVBA 4I04A 3E9SA 2ATOA 3H8CA 3PW3A 2HHNA 1CSBB 3P5XA 2DJGB 3MJ5A 1ME3A 2XU3A 1MIRA 1NL6A 5EF4A 1GECE 1BGOA 3QT4A 2R9FA 1PPPA 1ATKA 2JQGR 3BPFA 1KHQA 1U5IA 1AYUA 1U9VA 4BOSA 3BY4A 4K7CA 1QMYA 3PBHA 1Y08A 3LFYA 2C0YA 2Z84A 4CDFB 4DMXA 1EWMA 1HUCB 4MSXA 2DZYA 5FPWA 2XU5A 1CS8A 4PP1A 4MM3B 4XZXA 2DCCA 3KWZA 1MEGA 2FYEA 3QSDA 1KFUL 3N3GA 2P0RA 4RF1A 3C9EA 3RVVA 1KXRA 3H8BA 3WXFA 3MHHA 5CVOB 3OF9A 1A6RA 4X6IA 1F29A 4BS6A 1CJLA 2ARYA 4CDCB 4YYUA 1Q6KA 2GHUA 4FK5A 5CVMA 5J94A 4BOUA 1DKIA 1AU3A 4BOZA 3WXGA 1PXVA 4XR7A 1EWPA 4OVZA 2YJ8A 2R6NA 3AI8A 2JQFR 2BDZA 4G54A 1YZBA 3USVA 1S4VA 2DC6A 1PPNA 3I3TA 2NQIA 2G7YA 3PRMA 3DF0A 2R9NA 1MHWA 4W4UA 2FQ9A 3B79A 4BOQA 1QOLA 3H7DA 3E1ZB 1NLJA 1PPOA 5KO3A 1U9XA 3BC3A 3N3KA 2YJ9A 1TLOA 3RVXA 3GCBA 4IUMA 4Q8GA 4CDEB 2FO5A 3HD3A 1NB3A 2XU1A 4Q8HA 2IBIA 1CQDA 3KFQA 3O0UA 3BOWA 4P16A 3K24A 1Y4HA 3WXEA 3O65A 4PI3A 4I07A 4AXLA 3U8EA 1F2BA 1PVJA 2B1MA 2XU4A 3P5UA 2HWKA 1ICFA 2P86A 5CVNB 3P5WA 1AECA 2GFOA 4N4ZA 1CTEA 2OP3A 1PPDA 3HHIA 4RY2A 3K8UA 1SNKA 5EGWA 3ZNHA 8PCHA 2BTWB 3PRPA 4WURA 4CZWA 1CV8A 1F2AA 2OULA 6PADA 2HD5A 3H6SA 3KW9A 2PREA 1NB5A 4QH6A 4YVAA 2ACTA 1CB5A 3IV2A 2BU3A 3KKUA 3MP2A 2VHFA 1BP4A 2F1GA 2DCBA 4D8BA 2O6XA 2AU1A 4REZA 3MTVA 1MEMA 4YYQA 2AUXA 2AYNA 1K3BB 4PP2E 4YYVA 4I05A 2IPPB 1VSNA 2FT2A 2G6DA 3TNXA 5F02A 1FH0A 4XUIA
chains in the Genus database with same CATH topology
4D8EA 2FE8A 1YZBA 4RF0A 4M0WA 2DOSA 3BBAA 4BOPA 2UZJA 2AGAA 3PRMA 4IP3A 4R3DA 5EZSA 3E9SA 5E6JA 4BOQA 3W30A 5KO3A 3MJ5A 3BB7A 4IUMA 3PHWA 4D8IA 4ZTBA 4HXDB 4P16A 4PT5A 3O65A 4RKXA 3B21A 2J7QA 3PSEA 1PVJA 4BOSA 3BY4A 2HWKA 4GUAA 4OW0A 3IFUA 3TMPA 3PHXA 2Z84A 3ZNHA 2JTCA 2BTWB 3PRPA 4WURA 5EZQA 4MM3B 4XZXA 2JRIA 3PHUA 3RNVA 3OQCA 4RF1A 3W31A 1UKFA 2BU3A 2J7QC 3MP2A 2BTWA 4OVZB 4D8BA 3C0RA 4REZA 3MTVA 4BOUA 4MI7A 3TRKA 1DKIA 4A5UA 4BOZA 3PT2A 4OVZA 4RNAA 5JZEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MP2 A;  2FE8 A;  4OVZ B;  4RF0 A;  4M0W A;  4WUR A;  4P16 A;  4R3D A;  4REZ A;  4PT5 A;  3E9S A;  4MM3 B;  5E6J A;  5KO3 A;  4OW0 A;  4OVZ A;  4RNA A;  3MJ5 A;  4RF1 A; 
#chains in the Genus database with same CATH topology
 2NQD B;  2DC7 A;  2HXZ A;  1EWL A;  4D8E A;  4FIP A;  3IMA A;  4RF0 A;  2AYO A;  1PCI A;  2DOS A;  4IP3 A;  1CPJ A;  5JA7 A;  1AYV A;  1M6D A;  4W5B A;  2B1N A;  3D6S A;  5CHV A;  5E6J A;  1PBH A;  1U9W A;  4P6G A;  2BDL A;  1PAD A;  4BQV A;  2PAD A;  4N8W A;  3CH2 X;  2R9O A;  2YJ2 A;  3OIS A;  4QRX A;  2E01 A;  2Y6E A;  4HXD B;  3OF8 A;  2OZ2 A;  2AVW A;  3IEJ A;  4DMY A;  4MZO A;  3B21 A;  1POP A;  1IWD A;  2Y5B A;  3S3Q A;  4OW0 A;  5A24 A;  2NQG A;  1TL9 A;  1CVZ A;  3IFU A;  4QRG A;  4BS5 A;  3PHX A;  3PDF A;  1GMY A;  3OVZ A;  2H7J A;  1O0E A;  3OVX A;  2JTC A;  3F5V A;  4OEL A;  1AU0 A;  4HWY A;  2HH5 A;  4N79 A;  5EZQ A;  1EWO A;  4QBB A;  1NQC A;  1GCB A;  3PHU A;  3HWN A;  9PAP A;  4WA6 A;  1AIM A;  2R9C A;  3MOR A;  2R9M A;  4PAD A;  4OVZ B;  4QRV A;  2G8J A;  3KWB X;  2VHS A;  2E02 A;  3C0R A;  1BQI A;  1ZCM A;  2FTD A;  2CIO A;  4MI7 A;  1KHP A;  3I06 A;  1ZIV A;  3K9M A;  3CBK A;  3PNR A;  3NHE A;  4YYR A;  1MS6 A;  5JZE A;  3S3R A;  1XKG A;  4BSQ A;  4YYS A;  2AUZ A;  1YK7 A;  1ME4 A;  1QXP A;  2DCA A;  2FRA A;  4M0W A;  4X6J A;  1VJV A;  3HHA A;  2UZJ A;  2AGA A;  4BOP A;  7PCK A;  1YAL A;  1SP4 B;  5EZS A;  5JH3 A;  1GLO A;  1TU6 A;  3IOQ A;  2AIM A;  4AXM A;  2YJB A;  1MDW A;  3W30 A;  1BY8 A;  1PE6 A;  1AU4 A;  2DJF B;  2E00 A;  1JQP A;  2P7U A;  2DC9 A;  3CBJ A;  3BB7 A;  3PHW A;  3CH3 X;  1STF E;  5CHT A;  1AU2 A;  1F2C A;  4D8I A;  1KFX L;  4ZTB A;  2AS8 A;  3BWK A;  4PT5 A;  3BPM A;  4W5C A;  4KLB A;  4RKX A;  2J7Q A;  3PSE A;  3F75 A;  1NPZ A;  3H89 A;  2CB5 A;  1YK8 A;  4GUA A;  2DZZ A;  2FRQ A;  1X9Y A;  4YYW A;  3KSE A;  3ERV A;  3TMP A;  3KX1 A;  4YV8 A;  4ZUX U;  3IUT A;  5K16 A;  2PNS A;  2E03 A;  2F7D A;  1ITO A;  3BCN A;  3ZUA A;  2JRI A;  4MZS A;  4BPV A;  3RNV A;  3OQC A;  3O1G A;  1UKF A;  3W31 A;  1PIP A;  3MTN A;  2J7Q C;  2G8E A;  1U9Q X;  2BTW A;  2DC8 A;  3P5V A;  2NQA A;  4FJC A;  2WBF X;  3LXS A;  3V6C A;  2FUD A;  1AYW A;  1EF7 A;  4P6E A;  1THE A;  4X6H A;  3V6E A;  3TRK A;  4A5U A;  3M99 A;  2PBH A;  3PT2 A;  2YJC A;  4RNA A;  3RVW A;  3MHS A;  2FE8 A;  3IHP A;  3N4C A;  1YT7 A;  2DCD A;  1DEU A;  1QDQ A;  3BBA A;  5PAD A;  1DF0 A;  4R3D A;  3QJ3 A;  4OEM A;  4CDD B;  1YVB A;  4I04 A;  3E9S A;  2ATO A;  3H8C A;  3PW3 A;  2HHN A;  1CSB B;  3P5X A;  2DJG B;  3MJ5 A;  1ME3 A;  2XU3 A;  1MIR A;  1NL6 A;  5EF4 A;  1GEC E;  1BGO A;  3QT4 A;  2R9F A;  1PPP A;  1ATK A;  2JQG R;  3BPF A;  1KHQ A;  1U5I A;  1AYU A;  1U9V A;  4BOS A;  3BY4 A;  4K7C A;  1QMY A;  3PBH A;  1Y08 A;  3LFY A;  2C0Y A;  2Z84 A;  4CDF B;  4DMX A;  1EWM A;  1HUC B;  4MSX A;  2DZY A;  5FPW A;  2XU5 A;  1CS8 A;  4PP1 A;  4MM3 B;  4XZX A;  2DCC A;  3KWZ A;  1MEG A;  2FYE A;  3QSD A;  1KFU L;  3N3G A;  2P0R A;  4RF1 A;  3C9E A;  3RVV A;  1KXR A;  3H8B A;  3WXF A;  3MHH A;  5CVO B;  3OF9 A;  1A6R A;  4X6I A;  1F29 A;  4BS6 A;  1CJL A;  2ARY A;  4CDC B;  4YYU A;  1Q6K A;  2GHU A;  4FK5 A;  5CVM A;  5J94 A;  4BOU A;  1DKI A;  1AU3 A;  4BOZ A;  3WXG A;  1PXV A;  4XR7 A;  1EWP A;  4OVZ A;  2YJ8 A;  2R6N A;  3AI8 A;  2JQF R;  2BDZ A;  4G54 A;  1YZB A;  3USV A;  1S4V A;  2DC6 A;  1PPN A;  3I3T A;  2NQI A;  2G7Y A;  3PRM A;  3DF0 A;  2R9N A;  1MHW A;  4W4U A;  2FQ9 A;  3B79 A;  4BOQ A;  1QOL A;  3H7D A;  3E1Z B;  1NLJ A;  1PPO A;  5KO3 A;  1U9X A;  3BC3 A;  3N3K A;  2YJ9 A;  1TLO A;  3RVX A;  3GCB A;  4IUM A;  4Q8G A;  4CDE B;  2FO5 A;  3HD3 A;  1NB3 A;  2XU1 A;  4Q8H A;  2IBI A;  1CQD A;  3KFQ A;  3O0U A;  3BOW A;  4P16 A;  3K24 A;  1Y4H A;  3WXE A;  3O65 A;  4PI3 A;  4I07 A;  4AXL A;  3U8E A;  1F2B A;  1PVJ A;  2B1M A;  2XU4 A;  3P5U A;  2HWK A;  1ICF A;  2P86 A;  5CVN B;  3P5W A;  1AEC A;  2GFO A;  4N4Z A;  1CTE A;  2OP3 A;  1PPD A;  3HHI A;  4RY2 A;  3K8U A;  1SNK A;  5EGW A;  3ZNH A;  8PCH A;  2BTW B;  3PRP A;  4WUR A;  4CZW A;  1CV8 A;  1F2A A;  2OUL A;  6PAD A;  2HD5 A;  3H6S A;  3KW9 A;  2PRE A;  1NB5 A;  4QH6 A;  4YVA A;  2ACT A;  1CB5 A;  3IV2 A;  2BU3 A;  3KKU A;  3MP2 A;  2VHF A;  1BP4 A;  2F1G A;  2DCB A;  4D8B A;  2O6X A;  2AU1 A;  4REZ A;  3MTV A;  1MEM A;  4YYQ A;  2AUX A;  2AYN A;  1K3B B;  4PP2 E;  4YYV A;  4I05 A;  2IPP B;  1VSN A;  2FT2 A;  2G6D A;  3TNX A;  5F02 A;  1FH0 A;  4XUI A; 
#chains in the Genus database with same CATH homology
 4D8E A;  2FE8 A;  1YZB A;  4RF0 A;  4M0W A;  2DOS A;  3BBA A;  4BOP A;  2UZJ A;  2AGA A;  3PRM A;  4IP3 A;  4R3D A;  5EZS A;  3E9S A;  5E6J A;  4BOQ A;  3W30 A;  5KO3 A;  3MJ5 A;  3BB7 A;  4IUM A;  3PHW A;  4D8I A;  4ZTB A;  4HXD B;  4P16 A;  4PT5 A;  3O65 A;  4RKX A;  3B21 A;  2J7Q A;  3PSE A;  1PVJ A;  4BOS A;  3BY4 A;  2HWK A;  4GUA A;  4OW0 A;  3IFU A;  3TMP A;  3PHX A;  2Z84 A;  3ZNH A;  2JTC A;  2BTW B;  3PRP A;  4WUR A;  5EZQ A;  4MM3 B;  4XZX A;  2JRI A;  3PHU A;  3RNV A;  3OQC A;  4RF1 A;  3W31 A;  1UKF A;  2BU3 A;  2J7Q C;  3MP2 A;  2BTW A;  4OVZ B;  4D8B A;  3C0R A;  4REZ A;  3MTV A;  4BOU A;  4MI7 A;  3TRK A;  1DKI A;  4A5U A;  4BOZ A;  3PT2 A;  4OVZ A;  4RNA A;  5JZE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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