2YJ2A

Cathepsin l with a nitrile inhibitor
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
220
structure length
219
Chain Sequence
APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTSDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Halogen Bonding at the Active Sites of Human Cathepsin L and Mek1 Kinase: Efficient Interactions in Different Environments.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
molecule keywords CATHEPSIN L1
total genus 72
structure length 219
sequence length 220
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2011-05-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2yj2A00
1CPJA 4OEMA 3C9EA 1AU0A 3OVZA 3V6EA 4BS6A 2OZ2A 2PADA 2AU1A 2NQAA 4X6HA 3I3TA 2G6DA 2Y5BA 2IBIA 1GECE 1O0EA 2NQGA 7PCKA 4X6IA 3LFYA 4QBBA 5CHVA 2DC7A 4YYQA 2DJFB 1BGOA 3PW3A 1PIPA 2AYNA 2WBFX 1NLJA 1SP4B 4QRVA 1ICFA 4BSQA 3HD3A 5PADA 4YYWA 2PNSA 1MDWA 3D6SA 3S3QA 1TLOA 4I05A 2R9OA 2AUXA 3QSDA 4MZOA 4FIPA 1KFUL 3DF0A 1EWPA 3KW9A 1YK7A 4CDDB 2G8EA 1PBHA 1S4VA 1F2CA 2XU3A 4YYSA 2BDZA 3MORA 1FH0A 1ME4A 3TNXA 1XKGA 4G54A 1Q6KA 2DZZA 1KHPA 2B1NA 2F7DA 3WXEA 4DMYA 3I06A 3H89A 2JQFR 3QJ3A 2FT2A 1AYUA 1U9WA 3USVA 3OVXA 4HWYA 1CV8A 1U9XA 5EF4A 3U8EA 4W4UA 3RVVA 1PE6A 4XR7A 1MIRA 1MS6A 1PPNA 3OF9A 3O0UA 1BY8A 3KWBX 1ZIVA 3ZUAA 8PCHA 3E1ZB 1EWOA 4N79A 4K7CA 1F2BA 2VHFA 2FO5A 4N4ZA 1NQCA 1K3BB 3IV2A 4WA6A 3K8UA 1CTEA 4W5CA 4YYRA 1NB3A 4FK5A 5CVOB 3CBJA 3KWZA 1SNKA 2R9NA 2R9FA 1CSBB 4X6JA 2JQGR 3BOWA 1M6DA 2NQIA 2P86A 2XU4A 3PDFA 2R9CA 3H7DA 4Q8GA 3N3KA 2VHSA 2YJBA 2O6XA 3P5WA 2FUDA 4FJCA 2E00A 1MEGA 3KX1A 5JA7A 5FPWA 2F1GA 4P6GA 2PREA 2NQDB 3IUTA 3NHEA 5A24A 1YALA 3BPFA 3CBKA 1CJLA 2AYOA 3WXGA 3B79A 4CDCB 4CZWA 2P0RA 2ACTA 1DF0A 3PBHA 4BQVA 2Y6EA 1PPDA 2AIMA 2HHNA 2YJ9A 1YK8A 3CH3X 2H7JA 9PAPA 1ATKA 3LXSA 1KHQA 1ME3A 2G8JA 3GCBA 1POPA 4N8WA 4XUIA 3V6CA 2DZYA 2ARYA 1AIMA 1YT7A 1TU6A 2BDLA 3OF8A 2OULA 3ERVA 3PNRA 2CIOA 5EGWA 2DCAA 5CVNB 3IMAA 1GCBA 1F2AA 1Y08A 4KLBA 4QRXA 2DC8A 2FTDA 1BP4A 2HH5A 2AS8A 3IHPA 2E01A 3F5VA 1VJVA 1X9YA 4QH6A 3F75A 1QXPA 3H8CA 4W5BA 1ZCMA 1THEA 3HHIA 1Y4HA 1HUCB 1EF7A 4PP2E 3O1GA 2P7UA 2XU5A 1TL9A 2YJCA 3MTNA 1MHWA 3N3GA 3KFQA 3N4CA 1U9QX 4I07A 3IEJA 3KSEA 1JQPA 1PCIA 3P5VA 3KKUA 3IOQA 3M99A 2FRQA 2IPPB 4P6EA 3RVXA 1MEMA 5JH3A 5K16A 3BCNA 2GHUA 1EWLA 3OISA 1F29A 2GFOA 3P5UA 1QMYA 4QRGA 5F02A 4MSXA 1GLOA 2AUZA 4AXLA 2R6NA 1ITOA 3BWKA 4AXMA 4RY2A 1BQIA 1DEUA 3HWNA 4BPVA 1KXRA 2FYEA 2R9MA 1CB5A 1STFE 1AECA 5J94A 3AI8A 3MHHA 4I04A 6PADA 3CH2X 2DC9A 2C0YA 3BC3A 3MHSA 4Q8HA 1IWDA 1VSNA 4PADA 1NL6A 3S3RA 1U5IA 2YJ2A 1AU3A 4PP1A 1PADA 2AVWA 3H8BA 4YV8A 3WXFA 2DCCA 3HHAA 2YJ8A 1A6RA 2DCDA 1YVBA 1PXVA 1AYVA 2HD5A 4YYUA 2HXZA 1NB5A 2B1MA 2ATOA 4CDEB 1GMYA 2XU1A 3BPMA 1EWMA 2DC6A 2FRAA 4YYVA 1PPPA 1U9VA 4DMXA 1PPOA 3QT4A 4YVAA 1CQDA 1QDQA 2PBHA 1KFXL 2G7YA 1QOLA 1CS8A 4MZSA 5CVMA 1NPZA 2CB5A 1AU2A 3RVWA 4ZUXU 2DCBA 2E02A 4OELA 1AYWA 2OP3A 4PI3A 5CHTA 3P5XA 2DJGB 3K9MA 4BS5A 2E03A 1AU4A 3H6SA 1CVZA 3K24A 2FQ9A 4CDFB
chains in the Genus database with same CATH superfamily
1CPJA 4OEMA 3C9EA 1AU0A 3OVZA 3V6EA 4BS6A 2OZ2A 2PADA 2AU1A 2NQAA 4X6HA 3I3TA 2G6DA 2Y5BA 2IBIA 1GECE 1O0EA 3TRKA 2BTWB 5JZEA 2NQGA 7PCKA 3O65A 4MI7A 4RNAA 4X6IA 3LFYA 4QBBA 5CHVA 2DC7A 4YYQA 4A5UA 2DJFB 1BGOA 3PW3A 1PIPA 2AYNA 2WBFX 5E6JA 1NLJA 1SP4B 4QRVA 1ICFA 4BSQA 3HD3A 5PADA 4YYWA 2PNSA 1MDWA 4XZXA 4D8BA 3D6SA 3S3QA 1TLOA 4I05A 2R9OA 2AUXA 3QSDA 4MZOA 4FIPA 1KFUL 3DF0A 1EWPA 3KW9A 1YK7A 4CDDB 2G8EA 3C0RA 1PBHA 3BY4A 1S4VA 3RNVA 1F2CA 2XU3A 4YYSA 2BDZA 3MORA 1FH0A 1ME4A 2DOSA 3TNXA 1XKGA 4G54A 1Q6KA 4BOUA 2DZZA 1KHPA 2B1NA 2F7DA 3WXEA 4DMYA 3I06A 3MP2A 3H89A 2JQFR 4D8IA 3QJ3A 2FT2A 1AYUA 1U9WA 3USVA 3OVXA 4HWYA 3B21A 4P16A 3IFUA 4R3DA 1CV8A 1U9XA 5EF4A 3U8EA 4W4UA 3RVVA 1PE6A 4XR7A 1MIRA 1MS6A 1PPNA 4IP3A 3OF9A 3O0UA 1BY8A 4ZTBA 2JRIA 4IUMA 3KWBX 1ZIVA 3ZUAA 8PCHA 3E1ZB 1EWOA 1DKIA 4N79A 4K7CA 1F2BA 2VHFA 2FO5A 4M0WA 4N4ZA 1NQCA 1K3BB 1UKFA 4OVZB 3IV2A 4WA6A 3ZNHA 3K8UA 3OQCA 1CTEA 4W5CA 4YYRA 1NB3A 4FK5A 5CVOB 3CBJA 3KWZA 1SNKA 2R9NA 2R9FA 1CSBB 4X6JA 2JQGR 3BOWA 1M6DA 2NQIA 2P86A 2XU4A 3PDFA 2R9CA 3H7DA 4Q8GA 3N3KA 2VHSA 2YJBA 2O6XA 3P5WA 2FUDA 4FJCA 4BOZA 2E00A 1MEGA 3KX1A 2BTWA 5JA7A 4BOPA 5FPWA 2F1GA 4P6GA 2PREA 2NQDB 3IUTA 3NHEA 5A24A 1YALA 3PHWA 3BPFA 3CBKA 1CJLA 2AYOA 3WXGA 3B79A 4CDCB 4CZWA 4RF1A 5KO3A 2P0RA 2ACTA 2JTCA 1DF0A 3PBHA 4BQVA 2Y6EA 4GUAA 1PPDA 2AIMA 2HHNA 2YJ9A 1YK8A 3CH3X 2H7JA 9PAPA 1ATKA 3LXSA 1KHQA 1ME3A 2G8JA 3GCBA 1POPA 4N8WA 1YZBA 4XUIA 3V6CA 2DZYA 2ARYA 1AIMA 1YT7A 1TU6A 2BDLA 3OF8A 3PRMA 2OULA 3ERVA 3PNRA 2CIOA 3E9SA 3BB7A 5EGWA 4REZA 2DCAA 5CVNB 3IMAA 1GCBA 1F2AA 1Y08A 4KLBA 4QRXA 4BOQA 2DC8A 2FTDA 1BP4A 2HH5A 2AS8A 3IHPA 3PRPA 2E01A 3F5VA 4OW0A 1VJVA 1X9YA 4QH6A 3F75A 1QXPA 3PHUA 3H8CA 4W5BA 1ZCMA 1THEA 2J7QA 3HHIA 1Y4HA 4BOSA 1HUCB 4OVZA 4RKXA 1EF7A 4PP2E 3O1GA 2P7UA 2XU5A 1TL9A 2YJCA 3MTNA 1MHWA 3N3GA 3KFQA 3N4CA 1U9QX 4I07A 3IEJA 4HXDB 3W31A 3KSEA 1JQPA 1PCIA 3P5VA 5EZQA 4WURA 3KKUA 3IOQA 3M99A 2FRQA 2IPPB 4P6EA 3RVXA 1MEMA 5JH3A 5K16A 3BCNA 2GHUA 1EWLA 4D8EA 3OISA 1F29A 2GFOA 3P5UA 1QMYA 4QRGA 5F02A 3TMPA 3BBAA 4MSXA 1GLOA 2AUZA 4AXLA 2R6NA 1ITOA 3BWKA 4AXMA 4MM3B 4RY2A 1BQIA 1DEUA 5EZSA 1PVJA 3HWNA 4BPVA 2UZJA 1KXRA 2FYEA 3MTVA 2Z84A 2R9MA 1CB5A 2BU3A 1STFE 1AECA 5J94A 4RF0A 3AI8A 3MHHA 4I04A 6PADA 3CH2X 2DC9A 2C0YA 3W30A 3BC3A 3MHSA 4Q8HA 1IWDA 1VSNA 3MJ5A 4PADA 1NL6A 3S3RA 1U5IA 2YJ2A 1AU3A 4PP1A 1PADA 2AVWA 3H8BA 4YV8A 3WXFA 2DCCA 3HHAA 3PSEA 3PT2A 2YJ8A 1A6RA 2DCDA 1YVBA 1PXVA 1AYVA 2HD5A 4YYUA 2HXZA 1NB5A 2B1MA 2ATOA 4CDEB 1GMYA 3BPMA 2XU1A 2AGAA 1EWMA 2DC6A 2FRAA 2J7QC 4YYVA 1PPPA 3PHXA 1U9VA 2HWKA 4DMXA 1PPOA 3QT4A 4YVAA 1CQDA 1QDQA 2PBHA 1KFXL 2G7YA 1QOLA 1CS8A 4MZSA 5CVMA 2FE8A 1NPZA 2CB5A 1AU2A 3RVWA 4ZUXU 2DCBA 2E02A 4OELA 1AYWA 2OP3A 4PI3A 5CHTA 3P5XA 2DJGB 3K9MA 4BS5A 2E03A 1AU4A 3H6SA 4PT5A 1CVZA 3K24A 2FQ9A 4CDFB
chains in the Genus database with same CATH topology
1CPJA 4OEMA 3C9EA 1AU0A 3OVZA 3V6EA 4BS6A 2OZ2A 2PADA 2AU1A 2NQAA 4X6HA 3I3TA 2G6DA 2Y5BA 2IBIA 1GECE 1O0EA 2NQGA 7PCKA 4X6IA 3LFYA 4QBBA 5CHVA 2DC7A 4YYQA 2DJFB 1BGOA 3PW3A 1PIPA 2AYNA 2WBFX 1NLJA 1SP4B 4QRVA 1ICFA 4BSQA 3HD3A 5PADA 4YYWA 2PNSA 1MDWA 3D6SA 3S3QA 1TLOA 4I05A 2R9OA 2AUXA 3QSDA 4MZOA 4FIPA 1KFUL 3DF0A 1EWPA 3KW9A 1YK7A 4CDDB 2G8EA 1PBHA 1S4VA 4NV8A 1F2CA 2XU3A 4YYSA 2BDZA 3MORA 1FH0A 1ME4A 3TNXA 1XKGA 4G54A 1Q6KA 2DZZA 1KHPA 2B1NA 2F7DA 3WXEA 4DMYA 3I06A 3H89A 2JQFR 3QJ3A 2FT2A 1AYUA 4BGFA 1U9WA 3USVA 3OVXA 4HWYA 1CV8A 1U9XA 5EF4A 3U8EA 4W4UA 3D9WA 3RVVA 1PE6A 4XR7A 1MIRA 1MS6A 1PPNA 3OF9A 3O0UA 1BY8A 1W5RA 3KWBX 1ZIVA 3ZUAA 8PCHA 1W6FA 3E1ZB 1EWOA 4N79A 4K7CA 1F2BA 2VHFA 2FO5A 4N4ZA 1NQCA 1K3BB 3IV2A 4WA6A 3K8UA 1CTEA 4W5CA 4YYRA 1NB3A 4FK5A 5CVOB 3CBJA 3KWZA 1SNKA 2R9NA 2R9FA 1CSBB 2VFCA 4X6JA 2JQGR 3BOWA 1M6DA 2NQIA 2P86A 2VFBA 2XU4A 3PDFA 2R9CA 3H7DA 4Q8GA 3N3KA 2VHSA 2YJBA 2O6XA 3P5WA 2FUDA 4FJCA 2E00A 1MEGA 3KX1A 5JA7A 5FPWA 2F1GA 4P6GA 2PREA 2NQDB 3IUTA 3NHEA 5A24A 1YALA 3BPFA 3CBKA 1CJLA 2AYOA 3WXGA 3B79A 4CDCB 2BSZA 4CZWA 2P0RA 2ACTA 1DF0A 3PBHA 4BQVA 2Y6EA 1PPDA 2AIMA 2HHNA 2YJ9A 1YK8A 3CH3X 2H7JA 9PAPA 1ATKA 3LXSA 1KHQA 1ME3A 2G8JA 3GCBA 1POPA 4N8WA 4XUIA 3V6CA 2DZYA 2ARYA 1AIMA 1YT7A 1TU6A 2BDLA 3OF8A 2OULA 3ERVA 3PNRA 2CIOA 5EGWA 2DCAA 5CVNB 3IMAA 1GCBA 1F2AA 1Y08A 4KLBA 4QRXA 2DC8A 2FTDA 1BP4A 2HH5A 2AS8A 1E2TA 3IHPA 2E01A 3F5VA 1VJVA 1X9YA 4QH6A 3F75A 1QXPA 3H8CA 4W5BA 1ZCMA 1THEA 3HHIA 1Y4HA 1HUCB 1EF7A 4PP2E 3O1GA 2P7UA 2XU5A 1TL9A 1GX3A 2YJCA 3MTNA 1MHWA 3N3GA 3KFQA 3N4CA 1U9QX 4I07A 3IEJA 3KSEA 1JQPA 1PCIA 3P5VA 3KKUA 3IOQA 3M99A 2FRQA 2IPPB 4P6EA 3RVXA 1MEMA 5JH3A 5K16A 3BCNA 2GHUA 1EWLA 3OISA 1F29A 2GFOA 3P5UA 1QMYA 4QRGA 5F02A 4MSXA 1GLOA 4GUZA 2AUZA 4AXLA 2R6NA 1ITOA 3BWKA 4AXMA 4RY2A 1BQIA 1DEUA 3HWNA 4BPVA 1KXRA 2FYEA 2R9MA 1CB5A 1STFE 1AECA 5J94A 3AI8A 3MHHA 4I04A 6PADA 3CH2X 2DC9A 2C0YA 3BC3A 3MHSA 4Q8HA 1IWDA 1VSNA 4PADA 1NL6A 3S3RA 1U5IA 2YJ2A 1AU3A 4PP1A 1PADA 2AVWA 3H8BA 4YV8A 3WXFA 2DCCA 3HHAA 2YJ8A 1A6RA 2DCDA 4NV7A 1YVBA 1PXVA 1AYVA 2HD5A 4YYUA 2HXZA 1NB5A 2B1MA 2ATOA 4CDEB 1GMYA 2XU1A 3BPMA 1EWMA 2DC6A 2FRAA 4YYVA 1PPPA 1U9VA 4DMXA 1PPOA 3QT4A 4YVAA 1CQDA 1QDQA 2PBHA 1W4TA 1KFXL 2G7YA 1QOLA 1CS8A 4MZSA 5CVMA 1NPZA 4C5PA 2CB5A 1AU2A 3RVWA 4ZUXU 2DCBA 2E02A 4OELA 1AYWA 2OP3A 4PI3A 5CHTA 3LTWA 3P5XA 2DJGB 3K9MA 4BS5A 2E03A 4B55A 1AU4A 3H6SA 1CVZA 3K24A 2FQ9A 4CDFB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CPJ A;  4OEM A;  3C9E A;  1AU0 A;  3OVZ A;  3V6E A;  4BS6 A;  2OZ2 A;  2PAD A;  2AU1 A;  2NQA A;  4X6H A;  3I3T A;  2G6D A;  2Y5B A;  2IBI A;  1GEC E;  1O0E A;  2NQG A;  7PCK A;  4X6I A;  3LFY A;  4QBB A;  5CHV A;  2DC7 A;  4YYQ A;  2DJF B;  1BGO A;  3PW3 A;  1PIP A;  2AYN A;  2WBF X;  1NLJ A;  1SP4 B;  4QRV A;  1ICF A;  4BSQ A;  3HD3 A;  5PAD A;  4YYW A;  2PNS A;  1MDW A;  3D6S A;  3S3Q A;  1TLO A;  4I05 A;  2R9O A;  2AUX A;  3QSD A;  4MZO A;  4FIP A;  1KFU L;  3DF0 A;  1EWP A;  3KW9 A;  1YK7 A;  4CDD B;  2G8E A;  1PBH A;  1S4V A;  1F2C A;  2XU3 A;  4YYS A;  2BDZ A;  3MOR A;  1FH0 A;  1ME4 A;  3TNX A;  1XKG A;  4G54 A;  1Q6K A;  2DZZ A;  1KHP A;  2B1N A;  2F7D A;  3WXE A;  4DMY A;  3I06 A;  3H89 A;  2JQF R;  3QJ3 A;  2FT2 A;  1AYU A;  1U9W A;  3USV A;  3OVX A;  4HWY A;  1CV8 A;  1U9X A;  5EF4 A;  3U8E A;  4W4U A;  3RVV A;  1PE6 A;  4XR7 A;  1MIR A;  1MS6 A;  1PPN A;  3OF9 A;  3O0U A;  1BY8 A;  3KWB X;  1ZIV A;  3ZUA A;  8PCH A;  3E1Z B;  1EWO A;  4N79 A;  4K7C A;  1F2B A;  2VHF A;  2FO5 A;  4N4Z A;  1NQC A;  1K3B B;  3IV2 A;  4WA6 A;  3K8U A;  1CTE A;  4W5C A;  4YYR A;  1NB3 A;  4FK5 A;  5CVO B;  3CBJ A;  3KWZ A;  1SNK A;  2R9N A;  2R9F A;  1CSB B;  4X6J A;  2JQG R;  3BOW A;  1M6D A;  2NQI A;  2P86 A;  2XU4 A;  3PDF A;  2R9C A;  3H7D A;  4Q8G A;  3N3K A;  2VHS A;  2YJB A;  2O6X A;  3P5W A;  2FUD A;  4FJC A;  2E00 A;  1MEG A;  3KX1 A;  5JA7 A;  5FPW A;  2F1G A;  4P6G A;  2PRE A;  2NQD B;  3IUT A;  3NHE A;  5A24 A;  1YAL A;  3BPF A;  3CBK A;  1CJL A;  2AYO A;  3WXG A;  3B79 A;  4CDC B;  4CZW A;  2P0R A;  2ACT A;  1DF0 A;  3PBH A;  4BQV A;  2Y6E A;  1PPD A;  2AIM A;  2HHN A;  2YJ9 A;  1YK8 A;  3CH3 X;  2H7J A;  9PAP A;  1ATK A;  3LXS A;  1KHQ A;  1ME3 A;  2G8J A;  3GCB A;  1POP A;  4N8W A;  4XUI A;  3V6C A;  2DZY A;  2ARY A;  1AIM A;  1YT7 A;  1TU6 A;  2BDL A;  3OF8 A;  2OUL A;  3ERV A;  3PNR A;  2CIO A;  5EGW A;  2DCA A;  5CVN B;  3IMA A;  1GCB A;  1F2A A;  1Y08 A;  4KLB A;  4QRX A;  2DC8 A;  2FTD A;  1BP4 A;  2HH5 A;  2AS8 A;  3IHP A;  2E01 A;  3F5V A;  1VJV A;  1X9Y A;  4QH6 A;  3F75 A;  1QXP A;  3H8C A;  4W5B A;  1ZCM A;  1THE A;  3HHI A;  1Y4H A;  1HUC B;  1EF7 A;  4PP2 E;  3O1G A;  2P7U A;  2XU5 A;  1TL9 A;  2YJC A;  3MTN A;  1MHW A;  3N3G A;  3KFQ A;  3N4C A;  1U9Q X;  4I07 A;  3IEJ A;  3KSE A;  1JQP A;  1PCI A;  3P5V A;  3KKU A;  3IOQ A;  3M99 A;  2FRQ A;  2IPP B;  4P6E A;  3RVX A;  1MEM A;  5JH3 A;  5K16 A;  3BCN A;  2GHU A;  1EWL A;  3OIS A;  1F29 A;  2GFO A;  3P5U A;  1QMY A;  4QRG A;  5F02 A;  4MSX A;  1GLO A;  2AUZ A;  4AXL A;  2R6N A;  1ITO A;  3BWK A;  4AXM A;  4RY2 A;  1BQI A;  1DEU A;  3HWN A;  4BPV A;  1KXR A;  2FYE A;  2R9M A;  1CB5 A;  1STF E;  1AEC A;  5J94 A;  3AI8 A;  3MHH A;  4I04 A;  6PAD A;  3CH2 X;  2DC9 A;  2C0Y A;  3BC3 A;  3MHS A;  4Q8H A;  1IWD A;  1VSN A;  4PAD A;  1NL6 A;  3S3R A;  1U5I A;  2YJ2 A;  1AU3 A;  4PP1 A;  1PAD A;  2AVW A;  3H8B A;  4YV8 A;  3WXF A;  2DCC A;  3HHA A;  2YJ8 A;  1A6R A;  2DCD A;  1YVB A;  1PXV A;  1AYV A;  2HD5 A;  4YYU A;  2HXZ A;  1NB5 A;  2B1M A;  2ATO A;  4CDE B;  1GMY A;  2XU1 A;  3BPM A;  1EWM A;  2DC6 A;  2FRA A;  4YYV A;  1PPP A;  1U9V A;  4DMX A;  1PPO A;  3QT4 A;  4YVA A;  1CQD A;  1QDQ A;  2PBH A;  1KFX L;  2G7Y A;  1QOL A;  1CS8 A;  4MZS A;  5CVM A;  1NPZ A;  2CB5 A;  1AU2 A;  3RVW A;  4ZUX U;  2DCB A;  2E02 A;  4OEL A;  1AYW A;  2OP3 A;  4PI3 A;  5CHT A;  3P5X A;  2DJG B;  3K9M A;  4BS5 A;  2E03 A;  1AU4 A;  3H6S A;  1CVZ A;  3K24 A;  2FQ9 A;  4CDF B; 
#chains in the Genus database with same CATH topology
 1CPJ A;  4OEM A;  3C9E A;  1AU0 A;  3OVZ A;  3V6E A;  4BS6 A;  2OZ2 A;  2PAD A;  2AU1 A;  2NQA A;  4X6H A;  3I3T A;  2G6D A;  2Y5B A;  2IBI A;  1GEC E;  1O0E A;  3TRK A;  2BTW B;  5JZE A;  2NQG A;  7PCK A;  3O65 A;  4MI7 A;  4RNA A;  4X6I A;  3LFY A;  4QBB A;  5CHV A;  2DC7 A;  4YYQ A;  4A5U A;  2DJF B;  1BGO A;  3PW3 A;  1PIP A;  2AYN A;  2WBF X;  5E6J A;  1NLJ A;  1SP4 B;  4QRV A;  1ICF A;  4BSQ A;  3HD3 A;  5PAD A;  4YYW A;  2PNS A;  1MDW A;  4XZX A;  4D8B A;  3D6S A;  3S3Q A;  1TLO A;  4I05 A;  2R9O A;  2AUX A;  3QSD A;  4MZO A;  4FIP A;  1KFU L;  3DF0 A;  1EWP A;  3KW9 A;  1YK7 A;  4CDD B;  2G8E A;  3C0R A;  1PBH A;  3BY4 A;  1S4V A;  3RNV A;  1F2C A;  2XU3 A;  4YYS A;  2BDZ A;  3MOR A;  1FH0 A;  1ME4 A;  2DOS A;  3TNX A;  1XKG A;  4G54 A;  1Q6K A;  4BOU A;  2DZZ A;  1KHP A;  2B1N A;  2F7D A;  3WXE A;  4DMY A;  3I06 A;  3MP2 A;  3H89 A;  2JQF R;  4D8I A;  3QJ3 A;  2FT2 A;  1AYU A;  1U9W A;  3USV A;  3OVX A;  4HWY A;  3B21 A;  4P16 A;  3IFU A;  4R3D A;  1CV8 A;  1U9X A;  5EF4 A;  3U8E A;  4W4U A;  3RVV A;  1PE6 A;  4XR7 A;  1MIR A;  1MS6 A;  1PPN A;  4IP3 A;  3OF9 A;  3O0U A;  1BY8 A;  4ZTB A;  2JRI A;  4IUM A;  3KWB X;  1ZIV A;  3ZUA A;  8PCH A;  3E1Z B;  1EWO A;  1DKI A;  4N79 A;  4K7C A;  1F2B A;  2VHF A;  2FO5 A;  4M0W A;  4N4Z A;  1NQC A;  1K3B B;  1UKF A;  4OVZ B;  3IV2 A;  4WA6 A;  3ZNH A;  3K8U A;  3OQC A;  1CTE A;  4W5C A;  4YYR A;  1NB3 A;  4FK5 A;  5CVO B;  3CBJ A;  3KWZ A;  1SNK A;  2R9N A;  2R9F A;  1CSB B;  4X6J A;  2JQG R;  3BOW A;  1M6D A;  2NQI A;  2P86 A;  2XU4 A;  3PDF A;  2R9C A;  3H7D A;  4Q8G A;  3N3K A;  2VHS A;  2YJB A;  2O6X A;  3P5W A;  2FUD A;  4FJC A;  4BOZ A;  2E00 A;  1MEG A;  3KX1 A;  2BTW A;  5JA7 A;  4BOP A;  5FPW A;  2F1G A;  4P6G A;  2PRE A;  2NQD B;  3IUT A;  3NHE A;  5A24 A;  1YAL A;  3PHW A;  3BPF A;  3CBK A;  1CJL A;  2AYO A;  3WXG A;  3B79 A;  4CDC B;  4CZW A;  4RF1 A;  5KO3 A;  2P0R A;  2ACT A;  2JTC A;  1DF0 A;  3PBH A;  4BQV A;  2Y6E A;  4GUA A;  1PPD A;  2AIM A;  2HHN A;  2YJ9 A;  1YK8 A;  3CH3 X;  2H7J A;  9PAP A;  1ATK A;  3LXS A;  1KHQ A;  1ME3 A;  2G8J A;  3GCB A;  1POP A;  4N8W A;  1YZB A;  4XUI A;  3V6C A;  2DZY A;  2ARY A;  1AIM A;  1YT7 A;  1TU6 A;  2BDL A;  3OF8 A;  3PRM A;  2OUL A;  3ERV A;  3PNR A;  2CIO A;  3E9S A;  3BB7 A;  5EGW A;  4REZ A;  2DCA A;  5CVN B;  3IMA A;  1GCB A;  1F2A A;  1Y08 A;  4KLB A;  4QRX A;  4BOQ A;  2DC8 A;  2FTD A;  1BP4 A;  2HH5 A;  2AS8 A;  3IHP A;  3PRP A;  2E01 A;  3F5V A;  4OW0 A;  1VJV A;  1X9Y A;  4QH6 A;  3F75 A;  1QXP A;  3PHU A;  3H8C A;  4W5B A;  1ZCM A;  1THE A;  2J7Q A;  3HHI A;  1Y4H A;  4BOS A;  1HUC B;  4OVZ A;  4RKX A;  1EF7 A;  4PP2 E;  3O1G A;  2P7U A;  2XU5 A;  1TL9 A;  2YJC A;  3MTN A;  1MHW A;  3N3G A;  3KFQ A;  3N4C A;  1U9Q X;  4I07 A;  3IEJ A;  4HXD B;  3W31 A;  3KSE A;  1JQP A;  1PCI A;  3P5V A;  5EZQ A;  4WUR A;  3KKU A;  3IOQ A;  3M99 A;  2FRQ A;  2IPP B;  4P6E A;  3RVX A;  1MEM A;  5JH3 A;  5K16 A;  3BCN A;  2GHU A;  1EWL A;  4D8E A;  3OIS A;  1F29 A;  2GFO A;  3P5U A;  1QMY A;  4QRG A;  5F02 A;  3TMP A;  3BBA A;  4MSX A;  1GLO A;  2AUZ A;  4AXL A;  2R6N A;  1ITO A;  3BWK A;  4AXM A;  4MM3 B;  4RY2 A;  1BQI A;  1DEU A;  5EZS A;  1PVJ A;  3HWN A;  4BPV A;  2UZJ A;  1KXR A;  2FYE A;  3MTV A;  2Z84 A;  2R9M A;  1CB5 A;  2BU3 A;  1STF E;  1AEC A;  5J94 A;  4RF0 A;  3AI8 A;  3MHH A;  4I04 A;  6PAD A;  3CH2 X;  2DC9 A;  2C0Y A;  3W30 A;  3BC3 A;  3MHS A;  4Q8H A;  1IWD A;  1VSN A;  3MJ5 A;  4PAD A;  1NL6 A;  3S3R A;  1U5I A;  2YJ2 A;  1AU3 A;  4PP1 A;  1PAD A;  2AVW A;  3H8B A;  4YV8 A;  3WXF A;  2DCC A;  3HHA A;  3PSE A;  3PT2 A;  2YJ8 A;  1A6R A;  2DCD A;  1YVB A;  1PXV A;  1AYV A;  2HD5 A;  4YYU A;  2HXZ A;  1NB5 A;  2B1M A;  2ATO A;  4CDE B;  1GMY A;  3BPM A;  2XU1 A;  2AGA A;  1EWM A;  2DC6 A;  2FRA A;  2J7Q C;  4YYV A;  1PPP A;  3PHX A;  1U9V A;  2HWK A;  4DMX A;  1PPO A;  3QT4 A;  4YVA A;  1CQD A;  1QDQ A;  2PBH A;  1KFX L;  2G7Y A;  1QOL A;  1CS8 A;  4MZS A;  5CVM A;  2FE8 A;  1NPZ A;  2CB5 A;  1AU2 A;  3RVW A;  4ZUX U;  2DCB A;  2E02 A;  4OEL A;  1AYW A;  2OP3 A;  4PI3 A;  5CHT A;  3P5X A;  2DJG B;  3K9M A;  4BS5 A;  2E03 A;  1AU4 A;  3H6S A;  4PT5 A;  1CVZ A;  3K24 A;  2FQ9 A;  4CDF B; 
#chains in the Genus database with same CATH homology
 1CPJ A;  4OEM A;  3C9E A;  1AU0 A;  3OVZ A;  3V6E A;  4BS6 A;  2OZ2 A;  2PAD A;  2AU1 A;  2NQA A;  4X6H A;  3I3T A;  2G6D A;  2Y5B A;  2IBI A;  1GEC E;  1O0E A;  2NQG A;  7PCK A;  4X6I A;  3LFY A;  4QBB A;  5CHV A;  2DC7 A;  4YYQ A;  2DJF B;  1BGO A;  3PW3 A;  1PIP A;  2AYN A;  2WBF X;  1NLJ A;  1SP4 B;  4QRV A;  1ICF A;  4BSQ A;  3HD3 A;  5PAD A;  4YYW A;  2PNS A;  1MDW A;  3D6S A;  3S3Q A;  1TLO A;  4I05 A;  2R9O A;  2AUX A;  3QSD A;  4MZO A;  4FIP A;  1KFU L;  3DF0 A;  1EWP A;  3KW9 A;  1YK7 A;  4CDD B;  2G8E A;  1PBH A;  1S4V A;  4NV8 A;  1F2C A;  2XU3 A;  4YYS A;  2BDZ A;  3MOR A;  1FH0 A;  1ME4 A;  3TNX A;  1XKG A;  4G54 A;  1Q6K A;  2DZZ A;  1KHP A;  2B1N A;  2F7D A;  3WXE A;  4DMY A;  3I06 A;  3H89 A;  2JQF R;  3QJ3 A;  2FT2 A;  1AYU A;  4BGF A;  1U9W A;  3USV A;  3OVX A;  4HWY A;  1CV8 A;  1U9X A;  5EF4 A;  3U8E A;  4W4U A;  3D9W A;  3RVV A;  1PE6 A;  4XR7 A;  1MIR A;  1MS6 A;  1PPN A;  3OF9 A;  3O0U A;  1BY8 A;  1W5R A;  3KWB X;  1ZIV A;  3ZUA A;  8PCH A;  1W6F A;  3E1Z B;  1EWO A;  4N79 A;  4K7C A;  1F2B A;  2VHF A;  2FO5 A;  4N4Z A;  1NQC A;  1K3B B;  3IV2 A;  4WA6 A;  3K8U A;  1CTE A;  4W5C A;  4YYR A;  1NB3 A;  4FK5 A;  5CVO B;  3CBJ A;  3KWZ A;  1SNK A;  2R9N A;  2R9F A;  1CSB B;  2VFC A;  4X6J A;  2JQG R;  3BOW A;  1M6D A;  2NQI A;  2P86 A;  2VFB A;  2XU4 A;  3PDF A;  2R9C A;  3H7D A;  4Q8G A;  3N3K A;  2VHS A;  2YJB A;  2O6X A;  3P5W A;  2FUD A;  4FJC A;  2E00 A;  1MEG A;  3KX1 A;  5JA7 A;  5FPW A;  2F1G A;  4P6G A;  2PRE A;  2NQD B;  3IUT A;  3NHE A;  5A24 A;  1YAL A;  3BPF A;  3CBK A;  1CJL A;  2AYO A;  3WXG A;  3B79 A;  4CDC B;  2BSZ A;  4CZW A;  2P0R A;  2ACT A;  1DF0 A;  3PBH A;  4BQV A;  2Y6E A;  1PPD A;  2AIM A;  2HHN A;  2YJ9 A;  1YK8 A;  3CH3 X;  2H7J A;  9PAP A;  1ATK A;  3LXS A;  1KHQ A;  1ME3 A;  2G8J A;  3GCB A;  1POP A;  4N8W A;  4XUI A;  3V6C A;  2DZY A;  2ARY A;  1AIM A;  1YT7 A;  1TU6 A;  2BDL A;  3OF8 A;  2OUL A;  3ERV A;  3PNR A;  2CIO A;  5EGW A;  2DCA A;  5CVN B;  3IMA A;  1GCB A;  1F2A A;  1Y08 A;  4KLB A;  4QRX A;  2DC8 A;  2FTD A;  1BP4 A;  2HH5 A;  2AS8 A;  1E2T A;  3IHP A;  2E01 A;  3F5V A;  1VJV A;  1X9Y A;  4QH6 A;  3F75 A;  1QXP A;  3H8C A;  4W5B A;  1ZCM A;  1THE A;  3HHI A;  1Y4H A;  1HUC B;  1EF7 A;  4PP2 E;  3O1G A;  2P7U A;  2XU5 A;  1TL9 A;  1GX3 A;  2YJC A;  3MTN A;  1MHW A;  3N3G A;  3KFQ A;  3N4C A;  1U9Q X;  4I07 A;  3IEJ A;  3KSE A;  1JQP A;  1PCI A;  3P5V A;  3KKU A;  3IOQ A;  3M99 A;  2FRQ A;  2IPP B;  4P6E A;  3RVX A;  1MEM A;  5JH3 A;  5K16 A;  3BCN A;  2GHU A;  1EWL A;  3OIS A;  1F29 A;  2GFO A;  3P5U A;  1QMY A;  4QRG A;  5F02 A;  4MSX A;  1GLO A;  4GUZ A;  2AUZ A;  4AXL A;  2R6N A;  1ITO A;  3BWK A;  4AXM A;  4RY2 A;  1BQI A;  1DEU A;  3HWN A;  4BPV A;  1KXR A;  2FYE A;  2R9M A;  1CB5 A;  1STF E;  1AEC A;  5J94 A;  3AI8 A;  3MHH A;  4I04 A;  6PAD A;  3CH2 X;  2DC9 A;  2C0Y A;  3BC3 A;  3MHS A;  4Q8H A;  1IWD A;  1VSN A;  4PAD A;  1NL6 A;  3S3R A;  1U5I A;  2YJ2 A;  1AU3 A;  4PP1 A;  1PAD A;  2AVW A;  3H8B A;  4YV8 A;  3WXF A;  2DCC A;  3HHA A;  2YJ8 A;  1A6R A;  2DCD A;  4NV7 A;  1YVB A;  1PXV A;  1AYV A;  2HD5 A;  4YYU A;  2HXZ A;  1NB5 A;  2B1M A;  2ATO A;  4CDE B;  1GMY A;  2XU1 A;  3BPM A;  1EWM A;  2DC6 A;  2FRA A;  4YYV A;  1PPP A;  1U9V A;  4DMX A;  1PPO A;  3QT4 A;  4YVA A;  1CQD A;  1QDQ A;  2PBH A;  1W4T A;  1KFX L;  2G7Y A;  1QOL A;  1CS8 A;  4MZS A;  5CVM A;  1NPZ A;  4C5P A;  2CB5 A;  1AU2 A;  3RVW A;  4ZUX U;  2DCB A;  2E02 A;  4OEL A;  1AYW A;  2OP3 A;  4PI3 A;  5CHT A;  3LTW A;  3P5X A;  2DJG B;  3K9M A;  4BS5 A;  2E03 A;  4B55 A;  1AU4 A;  3H6S A;  1CVZ A;  3K24 A;  2FQ9 A;  4CDF B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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