2YJ2A

Cathepsin l with a nitrile inhibitor
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
220
structure length
219
Chain Sequence
APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTSDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords CATHEPSIN L1
publication title Halogen Bonding at the Active Sites of Human Cathepsin L and Mek1 Kinase: Efficient Interactions in Different Environments.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 72
structure length 219
sequence length 220
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2011-05-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2yj2A00
4MZSA 1NQCA 1DF0A 1MEGA 2F1GA 2PREA 1A6RA 2H7JA 2DC9A 1EWLA 3OISA 2E03A 5A24A 3RVWA 3GCBA 6PADA 1U5IA 4BSQA 4OEMA 3H8BA 2WBFX 1PCIA 3HWNA 2FUDA 5CVMA 2ATOA 2JQGR 4K7CA 1PPOA 3N3KA 2AVWA 3P5VA 1EWPA 3MTNA 1KHQA 2R9MA 2FRAA 4WA6A 1QDQA 1F29A 2PADA 3D6SA 4YYUA 1AYWA 3LFYA 4QRVA 3OF8A 4CDCB 2OP3A 1EWMA 2ARYA 2JQFR 4FIPA 4X6JA 2G6DA 4DMYA 1MEMA 4YYRA 3K8UA 1ME4A 4I07A 1JQPA 3V6CA 2B1NA 1CB5A 2F7DA 4HWYA 2DZYA 2FTDA 4CZWA 3MHHA 1CQDA 1X9YA 1BQIA 4YYQA 3OF9A 1NPZA 3KKUA 2AUZA 1U9XA 1NB3A 3H7DA 1QXPA 4N4ZA 4W5CA 4QBBA 2G8JA 3MORA 2IPPB 4X6HA 3I3TA 1QOLA 3HHIA 4RY2A 2DC8A 1AYVA 4CDDB 1KHPA 4PI3A 3E1ZB 3KX1A 1BP4A 3IMAA 1AU0A 1BGOA 3KW9A 4CDFB 1XKGA 5EF4A 4W4UA 2NQIA 2YJCA 2FYEA 4DMXA 4N79A 3DF0A 5PADA 2B1MA 3I06A 3PW3A 2GFOA 3BWKA 2HH5A 2DJFB 3N4CA 2XU1A 1PPNA 2E02A 1IWDA 1M6DA 1POPA 2YJ8A 5CHTA 5F02A 4FK5A 3KFQA 3IHPA 3U8EA 3HD3A 4QRGA 1CJLA 3QJ3A 2NQAA 4N8WA 1MS6A 4Q8HA 3S3QA 4I04A 1PE6A 2YJ2A 1Y08A 2DCCA 4X6IA 1NB5A 1Q6KA 1NL6A 5JA7A 4P6GA 2AS8A 4Q8GA 3KWZA 1SP4B 4P6EA 1KXRA 1MIRA 2VHFA 3QSDA 1ZIVA 2P0RA 3TNXA 2YJBA 1AU4A 3KSEA 9PAPA 2P86A 3PNRA 2HXZA 2E00A 4PP2E 5K16A 2E01A 4PADA 1CTEA 3K9MA 1AU3A 4YYWA 1EWOA 2AIMA 4FJCA 1ATKA 1AECA 2NQGA 1TU6A 1O0EA 3BPFA 3AI8A 4PP1A 3KWBX 2R9OA 1BY8A 3PDFA 4YYVA 1ME3A 2BDLA 1NLJA 3RVVA 2FO5A 4YYSA 2IBIA 4OELA 1AYUA 2FQ9A 1YK7A 2DJGB 1VJVA 5CVNB 3P5XA 5CHVA 4AXMA 3O1GA 2G7YA 3CBJA 5EGWA 2FT2A 5J94A 2R9NA 2AU1A 1FH0A 3IV2A 2G8EA 4XUIA 3BOWA 1HUCB 1PPPA 2DCAA 2PNSA 1AU2A 2C0YA 1KFXL 2BDZA 2YJ9A 3IOQA 2AYOA 2XU4A 3C9EA 1GLOA 3CBKA 3PBHA 2Y6EA 3LXSA 1F2CA 2DCDA 1YVBA 1CS8A 1F2BA 4QRXA 2VHSA 2AYNA 1TL9A 4BS5A 1CV8A 2FRQA 2R6NA 1PADA 3IUTA 2ACTA 1QMYA 4BQVA 4QH6A 3H8CA 1STFE 1KFUL 3BPMA 4I05A 3WXEA 1EF7A 4G54A 1K3BB 1ICFA 1TLOA 2HHNA 1CPJA 1SNKA 3MHSA 4KLBA 2DC6A 3M99A 4MZOA 1U9QX 2NQDB 1VSNA 3CH3X 7PCKA 3HHAA 3N3GA 3O0UA 1YK8A 4CDEB 2DZZA 4W5BA 1THEA 1U9VA 3K24A 3V6EA 2OULA 3B79A 4MSXA 1F2AA 1GCBA 4BS6A 1YT7A 5JH3A 2HD5A 4YV8A 1GMYA 1CSBB 3OVXA 3F75A 2P7UA 1U9WA 2OZ2A 2DC7A 4YVAA 5CVOB 2O6XA 3BCNA 2XU3A 3NHEA 4XR7A 1ITOA 1DEUA 1MHWA 3H6SA 2XU5A 1PXVA 3S3RA 3F5VA 2DCBA 3IEJA 1Y4HA 1CVZA 3ERVA 8PCHA 5FPWA 2PBHA 3USVA 1PPDA 2R9CA 3OVZA 3RVXA 3ZUAA 2CIOA 3QT4A 3H89A 3P5WA 4AXLA 2Y5BA 3CH2X 3P5UA 2AUXA 3BC3A 1PBHA 1AIMA 4BPVA 2GHUA 1YALA 1S4VA 2CB5A 3WXGA 1MDWA 1ZCMA 3WXFA 1GECE 1PIPA 4ZUXU 2R9FA
chains in the Genus database with same CATH superfamily
4MZSA 1NQCA 1DF0A 1MEGA 2F1GA 2PREA 1A6RA 2H7JA 2DC9A 1EWLA 3OISA 2E03A 5A24A 3RVWA 3GCBA 6PADA 1U5IA 4BSQA 4OEMA 3H8BA 2WBFX 1PCIA 3HWNA 2FUDA 5CVMA 2ATOA 2JQGR 4RKXA 4K7CA 1PPOA 3N3KA 4BOZA 2AVWA 3P5VA 1EWPA 3MTNA 1KHQA 2R9MA 2FRAA 4WA6A 1QDQA 4RNAA 1F29A 2PADA 3D6SA 4YYUA 1AYWA 3LFYA 3MTVA 3MP2A 4QRVA 3OF8A 4CDCB 2OP3A 1EWMA 2ARYA 2JQFR 3C0RA 4FIPA 2J7QA 4X6JA 2G6DA 4DMYA 2HWKA 1UKFA 3PHUA 1MEMA 4YYRA 3K8UA 1ME4A 4A5UA 4BOSA 4I07A 1JQPA 3V6CA 2JRIA 2B1NA 1CB5A 2F7DA 4HWYA 2DZYA 2FTDA 4CZWA 3MHHA 1CQDA 1X9YA 1BQIA 4WURA 4YYQA 3OF9A 2UZJA 1NPZA 3KKUA 2AUZA 4XZXA 1U9XA 1NB3A 3H7DA 1QXPA 4N4ZA 4W5CA 4QBBA 2G8JA 3MORA 2IPPB 4X6HA 3I3TA 1QOLA 3PSEA 3HHIA 4RY2A 2DC8A 1AYVA 4CDDB 1KHPA 4PI3A 3E1ZB 3W30A 3KX1A 1BP4A 3IMAA 1AU0A 1BGOA 3KW9A 4CDFB 1XKGA 1YZBA 4W4UA 2NQIA 5EF4A 2YJCA 2FYEA 4DMXA 4N79A 3DF0A 5PADA 3ZNHA 2B1MA 3I06A 5E6JA 3PW3A 2GFOA 3BWKA 2HH5A 2DJFB 3N4CA 2XU1A 1PPNA 2E02A 1IWDA 2BU3A 1M6DA 1POPA 2YJ8A 5CHTA 5F02A 4FK5A 3KFQA 3IHPA 3U8EA 3HD3A 4QRGA 2DOSA 1CJLA 3QJ3A 2NQAA 4D8BA 4N8WA 1MS6A 4Q8HA 3S3QA 4I04A 1PE6A 2YJ2A 1Y08A 2DCCA 4X6IA 1NB5A 1Q6KA 1NL6A 5JA7A 4HXDB 4P6GA 2AS8A 4Q8GA 3RNVA 3KWZA 1SP4B 4P6EA 1KXRA 1MIRA 4MM3B 4IUMA 2VHFA 3QSDA 1ZIVA 2P0RA 3TNXA 2YJBA 1AU4A 2Z84A 3KSEA 4OVZA 2P86A 9PAPA 3PNRA 2HXZA 2E00A 4PP2E 5K16A 2E01A 4PADA 4RF0A 5EZSA 1CTEA 3K9MA 1AU3A 4R3DA 4YYWA 1EWOA 2AIMA 5KO3A 4FJCA 1ATKA 1AECA 3B21A 3PT2A 2NQGA 1TU6A 1O0EA 3BPFA 3AI8A 4PP1A 3PHWA 3KWBX 2R9OA 1BY8A 1DKIA 3PDFA 4YYVA 1ME3A 2BDLA 1NLJA 3RVVA 2FO5A 3IFUA 4YYSA 5JZEA 2IBIA 4OELA 4GUAA 1AYUA 2FQ9A 3BBAA 3BY4A 1YK7A 4OVZB 2DJGB 2BTWA 1VJVA 5CVNB 3P5XA 5CHVA 3O65A 4AXMA 3O1GA 4RF1A 2G7YA 3CBJA 5EGWA 4D8EA 2FT2A 5J94A 2R9NA 2AU1A 5EZQA 3TMPA 1FH0A 3IV2A 2G8EA 4XUIA 3BOWA 1HUCB 2AGAA 1PPPA 2DCAA 2PNSA 1AU2A 2C0YA 1KFXL 2BDZA 2YJ9A 4P16A 3IOQA 2AYOA 2XU4A 3C9EA 1GLOA 3CBKA 3PBHA 2Y6EA 3LXSA 1F2CA 3PRPA 2DCDA 4BOPA 1YVBA 1CS8A 1F2BA 4QRXA 2VHSA 2AYNA 1TL9A 4BS5A 3TRKA 1CV8A 2FRQA 2R6NA 1PADA 3IUTA 2ACTA 1QMYA 4BQVA 4QH6A 3H8CA 1STFE 1KFUL 2FE8A 3BPMA 4M0WA 4I05A 3WXEA 1EF7A 4G54A 1K3BB 1ICFA 1TLOA 2HHNA 4IP3A 1CPJA 4PT5A 1SNKA 3MHSA 4KLBA 2DC6A 3M99A 4MZOA 1U9QX 4D8IA 2NQDB 1VSNA 3CH3X 7PCKA 3HHAA 3N3GA 3O0UA 3MJ5A 1YK8A 4REZA 4CDEB 2DZZA 4W5BA 1THEA 3BB7A 1U9VA 3K24A 3V6EA 2OULA 3B79A 4MSXA 1F2AA 1GCBA 4BS6A 1YT7A 3PRMA 5JH3A 2HD5A 4YV8A 1GMYA 1CSBB 3OVXA 3F75A 4ZTBA 2P7UA 2J7QC 1U9WA 2OZ2A 2DC7A 2JTCA 4YVAA 5CVOB 2O6XA 3W31A 3BCNA 2XU3A 4OW0A 3NHEA 4BOQA 4XR7A 1ITOA 4MI7A 1DEUA 1MHWA 3H6SA 2XU5A 1PXVA 3S3RA 3F5VA 2DCBA 3IEJA 4BOUA 1Y4HA 1CVZA 3PHXA 3ERVA 8PCHA 1PVJA 3OQCA 5FPWA 2PBHA 3USVA 1PPDA 2R9CA 3OVZA 3RVXA 3ZUAA 2CIOA 3QT4A 3H89A 3P5WA 4AXLA 2Y5BA 3CH2X 3P5UA 2AUXA 3BC3A 1PBHA 1AIMA 3E9SA 4BPVA 2GHUA 1YALA 1S4VA 2CB5A 3WXGA 1MDWA 1ZCMA 3WXFA 2BTWB 1GECE 1PIPA 4ZUXU 2R9FA
chains in the Genus database with same CATH topology
4MZSA 1NQCA 1DF0A 1MEGA 2F1GA 2PREA 1A6RA 2H7JA 2DC9A 1EWLA 3OISA 2E03A 5A24A 3RVWA 3GCBA 6PADA 3D9WA 1U5IA 4BSQA 4OEMA 3H8BA 2WBFX 1PCIA 3HWNA 2FUDA 5CVMA 2ATOA 2JQGR 4K7CA 1PPOA 3N3KA 2AVWA 3P5VA 1EWPA 3MTNA 1KHQA 2R9MA 2FRAA 4WA6A 1QDQA 3LTWA 1F29A 2PADA 3D6SA 4YYUA 1AYWA 3LFYA 4QRVA 3OF8A 4CDCB 2OP3A 1EWMA 2ARYA 2JQFR 4FIPA 4X6JA 2G6DA 4DMYA 1MEMA 4YYRA 3K8UA 1ME4A 4I07A 1JQPA 3V6CA 2B1NA 1CB5A 2F7DA 4HWYA 2DZYA 2FTDA 4CZWA 4C5PA 3MHHA 1CQDA 1X9YA 1BQIA 4YYQA 1W6FA 3OF9A 1NPZA 3KKUA 2AUZA 1U9XA 1NB3A 3H7DA 1QXPA 4N4ZA 4W5CA 4QBBA 2G8JA 3MORA 2IPPB 4X6HA 3I3TA 1QOLA 3HHIA 4RY2A 2DC8A 1AYVA 4CDDB 1KHPA 4PI3A 4NV7A 3E1ZB 3KX1A 1BP4A 3IMAA 1AU0A 1BGOA 3KW9A 4CDFB 1XKGA 5EF4A 4W4UA 2NQIA 2YJCA 2FYEA 4DMXA 4N79A 3DF0A 5PADA 2B1MA 3I06A 3PW3A 2GFOA 3BWKA 2HH5A 2DJFB 3N4CA 2XU1A 1PPNA 2E02A 1IWDA 1M6DA 1POPA 2YJ8A 5CHTA 5F02A 1E2TA 4FK5A 3KFQA 3IHPA 3U8EA 3HD3A 4QRGA 1CJLA 3QJ3A 2NQAA 4N8WA 1MS6A 4Q8HA 3S3QA 4I04A 1PE6A 2YJ2A 1Y08A 2DCCA 4X6IA 1NB5A 1Q6KA 1NL6A 5JA7A 4P6GA 2AS8A 4Q8GA 3KWZA 1SP4B 1W5RA 4P6EA 1KXRA 1MIRA 2VHFA 3QSDA 1ZIVA 2P0RA 3TNXA 2YJBA 1AU4A 3KSEA 9PAPA 2P86A 3PNRA 2HXZA 2E00A 4PP2E 5K16A 2E01A 4PADA 1CTEA 3K9MA 1AU3A 4YYWA 1EWOA 2AIMA 4FJCA 1ATKA 1AECA 2NQGA 1TU6A 1O0EA 3BPFA 3AI8A 4PP1A 3KWBX 2R9OA 1BY8A 3PDFA 4YYVA 1ME3A 2BDLA 1NLJA 3RVVA 2FO5A 4YYSA 2IBIA 4OELA 1AYUA 2FQ9A 4NV8A 1YK7A 2DJGB 1VJVA 5CVNB 3P5XA 5CHVA 4AXMA 3O1GA 2G7YA 3CBJA 5EGWA 2FT2A 5J94A 1GX3A 2R9NA 2AU1A 1FH0A 3IV2A 2G8EA 4XUIA 3BOWA 1HUCB 1PPPA 2DCAA 2PNSA 1AU2A 2C0YA 1KFXL 2BDZA 2YJ9A 3IOQA 2AYOA 2XU4A 3C9EA 1GLOA 3CBKA 3PBHA 2Y6EA 3LXSA 1F2CA 2DCDA 1YVBA 1CS8A 1F2BA 2VFCA 4B55A 4QRXA 2VHSA 2AYNA 1TL9A 4BS5A 1CV8A 2FRQA 2R6NA 1PADA 3IUTA 2ACTA 1QMYA 4BQVA 4QH6A 3H8CA 1STFE 1KFUL 3BPMA 4I05A 3WXEA 1EF7A 4G54A 1K3BB 1ICFA 4GUZA 1TLOA 2HHNA 1CPJA 1SNKA 3MHSA 4KLBA 2DC6A 2BSZA 3M99A 4MZOA 1U9QX 2NQDB 1VSNA 3CH3X 7PCKA 3HHAA 3N3GA 3O0UA 1YK8A 4CDEB 2DZZA 4W5BA 1THEA 1U9VA 3K24A 3V6EA 2OULA 3B79A 4MSXA 1F2AA 1GCBA 4BS6A 1YT7A 5JH3A 2HD5A 4YV8A 1GMYA 1CSBB 3OVXA 3F75A 2P7UA 1U9WA 2OZ2A 2DC7A 4YVAA 5CVOB 2O6XA 3BCNA 2XU3A 3NHEA 4XR7A 1ITOA 1DEUA 1MHWA 3H6SA 2XU5A 1PXVA 3S3RA 3F5VA 2DCBA 3IEJA 1Y4HA 1CVZA 3ERVA 8PCHA 1W4TA 5FPWA 2PBHA 3USVA 1PPDA 2R9CA 2VFBA 3OVZA 3RVXA 3ZUAA 2CIOA 3QT4A 3H89A 3P5WA 4AXLA 2Y5BA 3CH2X 3P5UA 2AUXA 3BC3A 1PBHA 1AIMA 4BPVA 2GHUA 1YALA 1S4VA 2CB5A 3WXGA 1MDWA 1ZCMA 3WXFA 1GECE 4BGFA 1PIPA 4ZUXU 2R9FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MZS A;  1NQC A;  1DF0 A;  1MEG A;  2F1G A;  2PRE A;  1A6R A;  2H7J A;  2DC9 A;  1EWL A;  3OIS A;  2E03 A;  5A24 A;  3RVW A;  3GCB A;  6PAD A;  1U5I A;  4BSQ A;  4OEM A;  3H8B A;  2WBF X;  1PCI A;  3HWN A;  2FUD A;  5CVM A;  2ATO A;  2JQG R;  4K7C A;  1PPO A;  3N3K A;  2AVW A;  3P5V A;  1EWP A;  3MTN A;  1KHQ A;  2R9M A;  2FRA A;  4WA6 A;  1QDQ A;  1F29 A;  2PAD A;  3D6S A;  4YYU A;  1AYW A;  3LFY A;  4QRV A;  3OF8 A;  4CDC B;  2OP3 A;  1EWM A;  2ARY A;  2JQF R;  4FIP A;  4X6J A;  2G6D A;  4DMY A;  1MEM A;  4YYR A;  3K8U A;  1ME4 A;  4I07 A;  1JQP A;  3V6C A;  2B1N A;  1CB5 A;  2F7D A;  4HWY A;  2DZY A;  2FTD A;  4CZW A;  3MHH A;  1CQD A;  1X9Y A;  1BQI A;  4YYQ A;  3OF9 A;  1NPZ A;  3KKU A;  2AUZ A;  1U9X A;  1NB3 A;  3H7D A;  1QXP A;  4N4Z A;  4W5C A;  4QBB A;  2G8J A;  3MOR A;  2IPP B;  4X6H A;  3I3T A;  1QOL A;  3HHI A;  4RY2 A;  2DC8 A;  1AYV A;  4CDD B;  1KHP A;  4PI3 A;  3E1Z B;  3KX1 A;  1BP4 A;  3IMA A;  1AU0 A;  1BGO A;  3KW9 A;  4CDF B;  1XKG A;  5EF4 A;  4W4U A;  2NQI A;  2YJC A;  2FYE A;  4DMX A;  4N79 A;  3DF0 A;  5PAD A;  2B1M A;  3I06 A;  3PW3 A;  2GFO A;  3BWK A;  2HH5 A;  2DJF B;  3N4C A;  2XU1 A;  1PPN A;  2E02 A;  1IWD A;  1M6D A;  1POP A;  2YJ8 A;  5CHT A;  5F02 A;  4FK5 A;  3KFQ A;  3IHP A;  3U8E A;  3HD3 A;  4QRG A;  1CJL A;  3QJ3 A;  2NQA A;  4N8W A;  1MS6 A;  4Q8H A;  3S3Q A;  4I04 A;  1PE6 A;  2YJ2 A;  1Y08 A;  2DCC A;  4X6I A;  1NB5 A;  1Q6K A;  1NL6 A;  5JA7 A;  4P6G A;  2AS8 A;  4Q8G A;  3KWZ A;  1SP4 B;  4P6E A;  1KXR A;  1MIR A;  2VHF A;  3QSD A;  1ZIV A;  2P0R A;  3TNX A;  2YJB A;  1AU4 A;  3KSE A;  9PAP A;  2P86 A;  3PNR A;  2HXZ A;  2E00 A;  4PP2 E;  5K16 A;  2E01 A;  4PAD A;  1CTE A;  3K9M A;  1AU3 A;  4YYW A;  1EWO A;  2AIM A;  4FJC A;  1ATK A;  1AEC A;  2NQG A;  1TU6 A;  1O0E A;  3BPF A;  3AI8 A;  4PP1 A;  3KWB X;  2R9O A;  1BY8 A;  3PDF A;  4YYV A;  1ME3 A;  2BDL A;  1NLJ A;  3RVV A;  2FO5 A;  4YYS A;  2IBI A;  4OEL A;  1AYU A;  2FQ9 A;  1YK7 A;  2DJG B;  1VJV A;  5CVN B;  3P5X A;  5CHV A;  4AXM A;  3O1G A;  2G7Y A;  3CBJ A;  5EGW A;  2FT2 A;  5J94 A;  2R9N A;  2AU1 A;  1FH0 A;  3IV2 A;  2G8E A;  4XUI A;  3BOW A;  1HUC B;  1PPP A;  2DCA A;  2PNS A;  1AU2 A;  2C0Y A;  1KFX L;  2BDZ A;  2YJ9 A;  3IOQ A;  2AYO A;  2XU4 A;  3C9E A;  1GLO A;  3CBK A;  3PBH A;  2Y6E A;  3LXS A;  1F2C A;  2DCD A;  1YVB A;  1CS8 A;  1F2B A;  4QRX A;  2VHS A;  2AYN A;  1TL9 A;  4BS5 A;  1CV8 A;  2FRQ A;  2R6N A;  1PAD A;  3IUT A;  2ACT A;  1QMY A;  4BQV A;  4QH6 A;  3H8C A;  1STF E;  1KFU L;  3BPM A;  4I05 A;  3WXE A;  1EF7 A;  4G54 A;  1K3B B;  1ICF A;  1TLO A;  2HHN A;  1CPJ A;  1SNK A;  3MHS A;  4KLB A;  2DC6 A;  3M99 A;  4MZO A;  1U9Q X;  2NQD B;  1VSN A;  3CH3 X;  7PCK A;  3HHA A;  3N3G A;  3O0U A;  1YK8 A;  4CDE B;  2DZZ A;  4W5B A;  1THE A;  1U9V A;  3K24 A;  3V6E A;  2OUL A;  3B79 A;  4MSX A;  1F2A A;  1GCB A;  4BS6 A;  1YT7 A;  5JH3 A;  2HD5 A;  4YV8 A;  1GMY A;  1CSB B;  3OVX A;  3F75 A;  2P7U A;  1U9W A;  2OZ2 A;  2DC7 A;  4YVA A;  5CVO B;  2O6X A;  3BCN A;  2XU3 A;  3NHE A;  4XR7 A;  1ITO A;  1DEU A;  1MHW A;  3H6S A;  2XU5 A;  1PXV A;  3S3R A;  3F5V A;  2DCB A;  3IEJ A;  1Y4H A;  1CVZ A;  3ERV A;  8PCH A;  5FPW A;  2PBH A;  3USV A;  1PPD A;  2R9C A;  3OVZ A;  3RVX A;  3ZUA A;  2CIO A;  3QT4 A;  3H89 A;  3P5W A;  4AXL A;  2Y5B A;  3CH2 X;  3P5U A;  2AUX A;  3BC3 A;  1PBH A;  1AIM A;  4BPV A;  2GHU A;  1YAL A;  1S4V A;  2CB5 A;  3WXG A;  1MDW A;  1ZCM A;  3WXF A;  1GEC E;  1PIP A;  4ZUX U;  2R9F A; 
#chains in the Genus database with same CATH topology
 4MZS A;  1NQC A;  1DF0 A;  1MEG A;  2F1G A;  2PRE A;  1A6R A;  2H7J A;  2DC9 A;  1EWL A;  3OIS A;  2E03 A;  5A24 A;  3RVW A;  3GCB A;  6PAD A;  1U5I A;  4BSQ A;  4OEM A;  3H8B A;  2WBF X;  1PCI A;  3HWN A;  2FUD A;  5CVM A;  2ATO A;  2JQG R;  4RKX A;  4K7C A;  1PPO A;  3N3K A;  4BOZ A;  2AVW A;  3P5V A;  1EWP A;  3MTN A;  1KHQ A;  2R9M A;  2FRA A;  4WA6 A;  1QDQ A;  4RNA A;  1F29 A;  2PAD A;  3D6S A;  4YYU A;  1AYW A;  3LFY A;  3MTV A;  3MP2 A;  4QRV A;  3OF8 A;  4CDC B;  2OP3 A;  1EWM A;  2ARY A;  2JQF R;  3C0R A;  4FIP A;  2J7Q A;  4X6J A;  2G6D A;  4DMY A;  2HWK A;  1UKF A;  3PHU A;  1MEM A;  4YYR A;  3K8U A;  1ME4 A;  4A5U A;  4BOS A;  4I07 A;  1JQP A;  3V6C A;  2JRI A;  2B1N A;  1CB5 A;  2F7D A;  4HWY A;  2DZY A;  2FTD A;  4CZW A;  3MHH A;  1CQD A;  1X9Y A;  1BQI A;  4WUR A;  4YYQ A;  3OF9 A;  2UZJ A;  1NPZ A;  3KKU A;  2AUZ A;  4XZX A;  1U9X A;  1NB3 A;  3H7D A;  1QXP A;  4N4Z A;  4W5C A;  4QBB A;  2G8J A;  3MOR A;  2IPP B;  4X6H A;  3I3T A;  1QOL A;  3PSE A;  3HHI A;  4RY2 A;  2DC8 A;  1AYV A;  4CDD B;  1KHP A;  4PI3 A;  3E1Z B;  3W30 A;  3KX1 A;  1BP4 A;  3IMA A;  1AU0 A;  1BGO A;  3KW9 A;  4CDF B;  1XKG A;  1YZB A;  4W4U A;  2NQI A;  5EF4 A;  2YJC A;  2FYE A;  4DMX A;  4N79 A;  3DF0 A;  5PAD A;  3ZNH A;  2B1M A;  3I06 A;  5E6J A;  3PW3 A;  2GFO A;  3BWK A;  2HH5 A;  2DJF B;  3N4C A;  2XU1 A;  1PPN A;  2E02 A;  1IWD A;  2BU3 A;  1M6D A;  1POP A;  2YJ8 A;  5CHT A;  5F02 A;  4FK5 A;  3KFQ A;  3IHP A;  3U8E A;  3HD3 A;  4QRG A;  2DOS A;  1CJL A;  3QJ3 A;  2NQA A;  4D8B A;  4N8W A;  1MS6 A;  4Q8H A;  3S3Q A;  4I04 A;  1PE6 A;  2YJ2 A;  1Y08 A;  2DCC A;  4X6I A;  1NB5 A;  1Q6K A;  1NL6 A;  5JA7 A;  4HXD B;  4P6G A;  2AS8 A;  4Q8G A;  3RNV A;  3KWZ A;  1SP4 B;  4P6E A;  1KXR A;  1MIR A;  4MM3 B;  4IUM A;  2VHF A;  3QSD A;  1ZIV A;  2P0R A;  3TNX A;  2YJB A;  1AU4 A;  2Z84 A;  3KSE A;  4OVZ A;  2P86 A;  9PAP A;  3PNR A;  2HXZ A;  2E00 A;  4PP2 E;  5K16 A;  2E01 A;  4PAD A;  4RF0 A;  5EZS A;  1CTE A;  3K9M A;  1AU3 A;  4R3D A;  4YYW A;  1EWO A;  2AIM A;  5KO3 A;  4FJC A;  1ATK A;  1AEC A;  3B21 A;  3PT2 A;  2NQG A;  1TU6 A;  1O0E A;  3BPF A;  3AI8 A;  4PP1 A;  3PHW A;  3KWB X;  2R9O A;  1BY8 A;  1DKI A;  3PDF A;  4YYV A;  1ME3 A;  2BDL A;  1NLJ A;  3RVV A;  2FO5 A;  3IFU A;  4YYS A;  5JZE A;  2IBI A;  4OEL A;  4GUA A;  1AYU A;  2FQ9 A;  3BBA A;  3BY4 A;  1YK7 A;  4OVZ B;  2DJG B;  2BTW A;  1VJV A;  5CVN B;  3P5X A;  5CHV A;  3O65 A;  4AXM A;  3O1G A;  4RF1 A;  2G7Y A;  3CBJ A;  5EGW A;  4D8E A;  2FT2 A;  5J94 A;  2R9N A;  2AU1 A;  5EZQ A;  3TMP A;  1FH0 A;  3IV2 A;  2G8E A;  4XUI A;  3BOW A;  1HUC B;  2AGA A;  1PPP A;  2DCA A;  2PNS A;  1AU2 A;  2C0Y A;  1KFX L;  2BDZ A;  2YJ9 A;  4P16 A;  3IOQ A;  2AYO A;  2XU4 A;  3C9E A;  1GLO A;  3CBK A;  3PBH A;  2Y6E A;  3LXS A;  1F2C A;  3PRP A;  2DCD A;  4BOP A;  1YVB A;  1CS8 A;  1F2B A;  4QRX A;  2VHS A;  2AYN A;  1TL9 A;  4BS5 A;  3TRK A;  1CV8 A;  2FRQ A;  2R6N A;  1PAD A;  3IUT A;  2ACT A;  1QMY A;  4BQV A;  4QH6 A;  3H8C A;  1STF E;  1KFU L;  2FE8 A;  3BPM A;  4M0W A;  4I05 A;  3WXE A;  1EF7 A;  4G54 A;  1K3B B;  1ICF A;  1TLO A;  2HHN A;  4IP3 A;  1CPJ A;  4PT5 A;  1SNK A;  3MHS A;  4KLB A;  2DC6 A;  3M99 A;  4MZO A;  1U9Q X;  4D8I A;  2NQD B;  1VSN A;  3CH3 X;  7PCK A;  3HHA A;  3N3G A;  3O0U A;  3MJ5 A;  1YK8 A;  4REZ A;  4CDE B;  2DZZ A;  4W5B A;  1THE A;  3BB7 A;  1U9V A;  3K24 A;  3V6E A;  2OUL A;  3B79 A;  4MSX A;  1F2A A;  1GCB A;  4BS6 A;  1YT7 A;  3PRM A;  5JH3 A;  2HD5 A;  4YV8 A;  1GMY A;  1CSB B;  3OVX A;  3F75 A;  4ZTB A;  2P7U A;  2J7Q C;  1U9W A;  2OZ2 A;  2DC7 A;  2JTC A;  4YVA A;  5CVO B;  2O6X A;  3W31 A;  3BCN A;  2XU3 A;  4OW0 A;  3NHE A;  4BOQ A;  4XR7 A;  1ITO A;  4MI7 A;  1DEU A;  1MHW A;  3H6S A;  2XU5 A;  1PXV A;  3S3R A;  3F5V A;  2DCB A;  3IEJ A;  4BOU A;  1Y4H A;  1CVZ A;  3PHX A;  3ERV A;  8PCH A;  1PVJ A;  3OQC A;  5FPW A;  2PBH A;  3USV A;  1PPD A;  2R9C A;  3OVZ A;  3RVX A;  3ZUA A;  2CIO A;  3QT4 A;  3H89 A;  3P5W A;  4AXL A;  2Y5B A;  3CH2 X;  3P5U A;  2AUX A;  3BC3 A;  1PBH A;  1AIM A;  3E9S A;  4BPV A;  2GHU A;  1YAL A;  1S4V A;  2CB5 A;  3WXG A;  1MDW A;  1ZCM A;  3WXF A;  2BTW B;  1GEC E;  1PIP A;  4ZUX U;  2R9F A; 
#chains in the Genus database with same CATH homology
 4MZS A;  1NQC A;  1DF0 A;  1MEG A;  2F1G A;  2PRE A;  1A6R A;  2H7J A;  2DC9 A;  1EWL A;  3OIS A;  2E03 A;  5A24 A;  3RVW A;  3GCB A;  6PAD A;  3D9W A;  1U5I A;  4BSQ A;  4OEM A;  3H8B A;  2WBF X;  1PCI A;  3HWN A;  2FUD A;  5CVM A;  2ATO A;  2JQG R;  4K7C A;  1PPO A;  3N3K A;  2AVW A;  3P5V A;  1EWP A;  3MTN A;  1KHQ A;  2R9M A;  2FRA A;  4WA6 A;  1QDQ A;  3LTW A;  1F29 A;  2PAD A;  3D6S A;  4YYU A;  1AYW A;  3LFY A;  4QRV A;  3OF8 A;  4CDC B;  2OP3 A;  1EWM A;  2ARY A;  2JQF R;  4FIP A;  4X6J A;  2G6D A;  4DMY A;  1MEM A;  4YYR A;  3K8U A;  1ME4 A;  4I07 A;  1JQP A;  3V6C A;  2B1N A;  1CB5 A;  2F7D A;  4HWY A;  2DZY A;  2FTD A;  4CZW A;  4C5P A;  3MHH A;  1CQD A;  1X9Y A;  1BQI A;  4YYQ A;  1W6F A;  3OF9 A;  1NPZ A;  3KKU A;  2AUZ A;  1U9X A;  1NB3 A;  3H7D A;  1QXP A;  4N4Z A;  4W5C A;  4QBB A;  2G8J A;  3MOR A;  2IPP B;  4X6H A;  3I3T A;  1QOL A;  3HHI A;  4RY2 A;  2DC8 A;  1AYV A;  4CDD B;  1KHP A;  4PI3 A;  4NV7 A;  3E1Z B;  3KX1 A;  1BP4 A;  3IMA A;  1AU0 A;  1BGO A;  3KW9 A;  4CDF B;  1XKG A;  5EF4 A;  4W4U A;  2NQI A;  2YJC A;  2FYE A;  4DMX A;  4N79 A;  3DF0 A;  5PAD A;  2B1M A;  3I06 A;  3PW3 A;  2GFO A;  3BWK A;  2HH5 A;  2DJF B;  3N4C A;  2XU1 A;  1PPN A;  2E02 A;  1IWD A;  1M6D A;  1POP A;  2YJ8 A;  5CHT A;  5F02 A;  1E2T A;  4FK5 A;  3KFQ A;  3IHP A;  3U8E A;  3HD3 A;  4QRG A;  1CJL A;  3QJ3 A;  2NQA A;  4N8W A;  1MS6 A;  4Q8H A;  3S3Q A;  4I04 A;  1PE6 A;  2YJ2 A;  1Y08 A;  2DCC A;  4X6I A;  1NB5 A;  1Q6K A;  1NL6 A;  5JA7 A;  4P6G A;  2AS8 A;  4Q8G A;  3KWZ A;  1SP4 B;  1W5R A;  4P6E A;  1KXR A;  1MIR A;  2VHF A;  3QSD A;  1ZIV A;  2P0R A;  3TNX A;  2YJB A;  1AU4 A;  3KSE A;  9PAP A;  2P86 A;  3PNR A;  2HXZ A;  2E00 A;  4PP2 E;  5K16 A;  2E01 A;  4PAD A;  1CTE A;  3K9M A;  1AU3 A;  4YYW A;  1EWO A;  2AIM A;  4FJC A;  1ATK A;  1AEC A;  2NQG A;  1TU6 A;  1O0E A;  3BPF A;  3AI8 A;  4PP1 A;  3KWB X;  2R9O A;  1BY8 A;  3PDF A;  4YYV A;  1ME3 A;  2BDL A;  1NLJ A;  3RVV A;  2FO5 A;  4YYS A;  2IBI A;  4OEL A;  1AYU A;  2FQ9 A;  4NV8 A;  1YK7 A;  2DJG B;  1VJV A;  5CVN B;  3P5X A;  5CHV A;  4AXM A;  3O1G A;  2G7Y A;  3CBJ A;  5EGW A;  2FT2 A;  5J94 A;  1GX3 A;  2R9N A;  2AU1 A;  1FH0 A;  3IV2 A;  2G8E A;  4XUI A;  3BOW A;  1HUC B;  1PPP A;  2DCA A;  2PNS A;  1AU2 A;  2C0Y A;  1KFX L;  2BDZ A;  2YJ9 A;  3IOQ A;  2AYO A;  2XU4 A;  3C9E A;  1GLO A;  3CBK A;  3PBH A;  2Y6E A;  3LXS A;  1F2C A;  2DCD A;  1YVB A;  1CS8 A;  1F2B A;  2VFC A;  4B55 A;  4QRX A;  2VHS A;  2AYN A;  1TL9 A;  4BS5 A;  1CV8 A;  2FRQ A;  2R6N A;  1PAD A;  3IUT A;  2ACT A;  1QMY A;  4BQV A;  4QH6 A;  3H8C A;  1STF E;  1KFU L;  3BPM A;  4I05 A;  3WXE A;  1EF7 A;  4G54 A;  1K3B B;  1ICF A;  4GUZ A;  1TLO A;  2HHN A;  1CPJ A;  1SNK A;  3MHS A;  4KLB A;  2DC6 A;  2BSZ A;  3M99 A;  4MZO A;  1U9Q X;  2NQD B;  1VSN A;  3CH3 X;  7PCK A;  3HHA A;  3N3G A;  3O0U A;  1YK8 A;  4CDE B;  2DZZ A;  4W5B A;  1THE A;  1U9V A;  3K24 A;  3V6E A;  2OUL A;  3B79 A;  4MSX A;  1F2A A;  1GCB A;  4BS6 A;  1YT7 A;  5JH3 A;  2HD5 A;  4YV8 A;  1GMY A;  1CSB B;  3OVX A;  3F75 A;  2P7U A;  1U9W A;  2OZ2 A;  2DC7 A;  4YVA A;  5CVO B;  2O6X A;  3BCN A;  2XU3 A;  3NHE A;  4XR7 A;  1ITO A;  1DEU A;  1MHW A;  3H6S A;  2XU5 A;  1PXV A;  3S3R A;  3F5V A;  2DCB A;  3IEJ A;  1Y4H A;  1CVZ A;  3ERV A;  8PCH A;  1W4T A;  5FPW A;  2PBH A;  3USV A;  1PPD A;  2R9C A;  2VFB A;  3OVZ A;  3RVX A;  3ZUA A;  2CIO A;  3QT4 A;  3H89 A;  3P5W A;  4AXL A;  2Y5B A;  3CH2 X;  3P5U A;  2AUX A;  3BC3 A;  1PBH A;  1AIM A;  4BPV A;  2GHU A;  1YAL A;  1S4V A;  2CB5 A;  3WXG A;  1MDW A;  1ZCM A;  3WXF A;  1GEC E;  4BGF A;  1PIP A;  4ZUX U;  2R9F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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