2YJ2A

Cathepsin l with a nitrile inhibitor
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
220
structure length
219
Chain Sequence
APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTSDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Halogen Bonding at the Active Sites of Human Cathepsin L and Mek1 Kinase: Efficient Interactions in Different Environments.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
molecule keywords CATHEPSIN L1
total genus 72
structure length 219
sequence length 220
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2011-05-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2yj2A00
1PPNA 3P5VA 4Q8HA 1NQCA 2YJ2A 2G6DA 1CQDA 2Y6EA 2R9FA 3S3QA 1SP4B 3KX1A 1EWOA 4QRVA 3KKUA 1ME4A 2FT2A 3LFYA 1CVZA 4OELA 3NHEA 1BQIA 2NQDB 2FQ9A 1AU0A 2G8JA 4FJCA 2JQGR 4AXLA 2YJCA 3V6EA 4PI3A 1AYUA 1F2CA 3MTNA 1CB5A 1YALA 4QBBA 2C0YA 2YJBA 3OF8A 1TU6A 3P5UA 1CTEA 1YT7A 1PPDA 3F5VA 1AU2A 1PADA 3WXEA 2P86A 1MDWA 3WXGA 2DC7A 5PADA 5K16A 2DJFB 2AUZA 2XU3A 1ITOA 1MS6A 2DC9A 1YK8A 2HH5A 1KXRA 1VSNA 4CZWA 1NB3A 3CBJA 3PW3A 2F1GA 3BOWA 2Y5BA 4QRGA 4YYUA 1AIMA 3OF9A 1QMYA 3IEJA 3KWBX 2PREA 1U9XA 1KHQA 4PP2E 1QOLA 1VJVA 2OULA 1CS8A 2PADA 8PCHA 2PBHA 2DZZA 2AUXA 1YVBA 2DCCA 1KFUL 1DEUA 4MZOA 1HUCB 3H7DA 5EGWA 4WA6A 2WBFX 3K24A 4YYSA 3U8EA 1Y08A 7PCKA 3K9MA 4FK5A 3S3RA 3KSEA 4K7CA 5JA7A 1PBHA 4I05A 4YVAA 1BGOA 2BDLA 2YJ8A 5J94A 3USVA 2GHUA 4X6IA 2XU1A 2R9NA 2E02A 3GCBA 4XR7A 2F7DA 4XUIA 3PBHA 1NB5A 1CV8A 2G8EA 3KW9A 2H7JA 5EF4A 1X9YA 3N3KA 2B1MA 1PIPA 3P5WA 2BDZA 3OVXA 3LXSA 3IHPA 1XKGA 3BPMA 1NL6A 2AU1A 2P7UA 2E00A 5CVOB 2DCBA 3QT4A 5CVNB 4DMYA 2R9CA 2P0RA 2VHSA 3BC3A 4YV8A 1QDQA 1GLOA 5CHVA 4YYRA 3PNRA 4QH6A 3RVWA 1EWMA 5CVMA 1U9WA 2HD5A 3OISA 3RVVA 3CBKA 4AXMA 1AU4A 3IOQA 1BY8A 1KFXL 1SNKA 3KFQA 2NQIA 2B1NA 2CB5A 5A24A 4N8WA 4YYWA 2AYNA 3QJ3A 2R9OA 1Y4HA 1IWDA 2G7YA 1MIRA 1AYVA 3KWZA 5CHTA 4YYVA 3D6SA 4BPVA 3IV2A 4FIPA 1EWLA 1GCBA 2AYOA 1MEGA 3MHHA 1EWPA 2HXZA 3O1GA 4RY2A 1YK7A 1DF0A 1PE6A 4BSQA 2R6NA 3AI8A 2R9MA 4I07A 2PNSA 3QSDA 1K3BB 2E03A 3H89A 3CH2X 2ACTA 1AECA 4KLBA 3MHSA 4BS5A 1F29A 1POPA 2IPPB 1ICFA 2E01A 1S4VA 2NQAA 3H6SA 3C9EA 3V6CA 2JQFR 2FRAA 1U9QX 2O6XA 3DF0A 3HWNA 2ATOA 4W5BA 3MORA 5JH3A 2OZ2A 2FTDA 3CH3X 1PPPA 1TLOA 3I3TA 3N4CA 3IMAA 2FRQA 1PXVA 2OP3A 4P6EA 1TL9A 1FH0A 3P5XA 4OEMA 2YJ9A 3TNXA 2DZYA 2HHNA 2XU4A 3E1ZB 2AS8A 1F2AA 4CDDB 4CDFB 1CJLA 1NLJA 1QXPA 4X6HA 1MHWA 2XU5A 1U5IA 3IUTA 3O0UA 2DJGB 3BCNA 1O0EA 3F75A 2DC6A 1A6RA 1CSBB 3BPFA 3H8BA 1AYWA 1GECE 4ZUXU 3N3GA 1THEA 2ARYA 4X6JA 1F2BA 1MEMA 3ERVA 3RVXA 2NQGA 3M99A 3BWKA 3ZUAA 4CDEB 2DC8A 1ZCMA 4P6GA 1GMYA 2DCAA 3H8CA 3I06A 4BQVA 4W5CA 4MSXA 4QRXA 2AVWA 4Q8GA 4YYQA 4MZSA 4N4ZA 1JQPA 1KHPA 3HHIA 6PADA 4DMXA 4N79A 3B79A 2FYEA 3HHAA 2FUDA 4PADA 1ZIVA 1M6DA 3PDFA 1PPOA 4BS6A 1ME3A 1EF7A 4I04A 1ATKA 3K8UA 1CPJA 2CIOA 2FO5A 2VHFA 1PCIA 1STFE 5FPWA 2IBIA 1AU3A 1NPZA 2AIMA 4PP1A 1U9VA 2GFOA 4CDCB 4HWYA 3HD3A 1BP4A 4W4UA 2DCDA 3WXFA 9PAPA 1Q6KA 4G54A 3OVZA 5F02A
chains in the Genus database with same CATH superfamily
4BOQA 1PPNA 3P5VA 3RNVA 4Q8HA 3MTVA 1NQCA 2YJ2A 2G6DA 1CQDA 2BU3A 2Y6EA 2R9FA 3S3QA 1SP4B 3KX1A 1EWOA 3PHWA 3TRKA 4QRVA 3KKUA 1ME4A 2FT2A 5E6JA 3LFYA 1CVZA 3O65A 4OELA 3NHEA 1BQIA 2NQDB 2FQ9A 3TMPA 1AU0A 2G8JA 4FJCA 2JQGR 4AXLA 2YJCA 4OVZB 3MP2A 3V6EA 4D8BA 2DOSA 4PI3A 1AYUA 1F2CA 3MTNA 1CB5A 1YALA 3PHXA 1UKFA 4QBBA 2C0YA 3W31A 2YJBA 3OF8A 1TU6A 3P5UA 1CTEA 1YT7A 1PPDA 3F5VA 1AU2A 1PADA 3WXEA 2P86A 1MDWA 3WXGA 4P16A 2DC7A 5PADA 1PVJA 5K16A 2DJFB 2AUZA 2XU3A 1ITOA 1MS6A 2DC9A 1YK8A 2HH5A 1KXRA 1VSNA 4CZWA 1NB3A 3CBJA 3PW3A 2F1GA 3BOWA 2Y5BA 4QRGA 4YYUA 3ZNHA 1AIMA 3OF9A 1QMYA 3IEJA 3KWBX 2PREA 1U9XA 1KHQA 4PP2E 1QOLA 1VJVA 2OULA 1CS8A 2PADA 8PCHA 2PBHA 2DZZA 2AUXA 1YVBA 2DCCA 1KFUL 1DEUA 4MZOA 1HUCB 3H7DA 5EGWA 5EZSA 2HWKA 4WA6A 2WBFX 3K24A 4YYSA 3U8EA 1Y08A 7PCKA 2JRIA 4BOZA 3K9MA 4FK5A 3S3RA 3KSEA 4K7CA 4BOSA 3MJ5A 5JA7A 1PBHA 4I05A 3PT2A 4YVAA 1BGOA 2BDLA 2YJ8A 3C0RA 5J94A 3USVA 4GUAA 2GHUA 4X6IA 4D8IA 2XU1A 2R9NA 2E02A 3GCBA 4XR7A 2F7DA 4XUIA 2J7QA 3PBHA 1NB5A 1CV8A 2G8EA 3IFUA 3KW9A 2H7JA 3PSEA 5EF4A 1X9YA 3N3KA 2B1MA 1PIPA 3P5WA 2BDZA 4M0WA 3OVXA 3LXSA 3IHPA 1XKGA 4BOUA 4MM3B 3BPMA 4IP3A 1NL6A 2AU1A 2P7UA 2E00A 5CVOB 2DCBA 3QT4A 5CVNB 4DMYA 2R9CA 2P0RA 2VHSA 3BC3A 4YV8A 1QDQA 1GLOA 5CHVA 4YYRA 3PNRA 4XZXA 4QH6A 3RVWA 1EWMA 5CVMA 1U9WA 2HD5A 3OISA 3W30A 3RVVA 3CBKA 4AXMA 1AU4A 3IOQA 4RKXA 1BY8A 4R3DA 4IUMA 1KFXL 1SNKA 3KFQA 2NQIA 2B1NA 2CB5A 5A24A 4N8WA 3E9SA 4YYWA 2AYNA 3QJ3A 2R9OA 1Y4HA 1IWDA 2G7YA 1MIRA 1AYVA 3KWZA 5CHTA 4YYVA 3D6SA 4BPVA 3IV2A 4FIPA 1EWLA 1GCBA 2AYOA 1MEGA 3MHHA 4OW0A 1EWPA 2HXZA 3O1GA 4RY2A 1YK7A 1DF0A 1PE6A 4BSQA 2R6NA 4ZTBA 3AI8A 4HXDB 2R9MA 4I07A 2PNSA 3OQCA 3QSDA 1K3BB 2E03A 2AGAA 3CH2X 3H89A 2ACTA 1AECA 4KLBA 3MHSA 4OVZA 4BS5A 1F29A 1POPA 2IPPB 1ICFA 2E01A 1S4VA 2NQAA 3H6SA 3C9EA 3V6CA 2JQFR 1YZBA 3PHUA 2FRAA 1U9QX 2O6XA 3DF0A 3PRPA 3HWNA 2ATOA 4W5BA 4RNAA 3MORA 5JH3A 2OZ2A 2FTDA 3CH3X 1PPPA 1TLOA 3I3TA 3N4CA 3IMAA 2FRQA 1PXVA 2OP3A 4WURA 3BBAA 4BOPA 4P6EA 1TL9A 2BTWA 1FH0A 3P5XA 4OEMA 2YJ9A 3TNXA 2DZYA 2HHNA 2XU4A 4RF0A 3E1ZB 2AS8A 1F2AA 4CDDB 2Z84A 4CDFB 1CJLA 1NLJA 1QXPA 4X6HA 1MHWA 2XU5A 1U5IA 3IUTA 3O0UA 2DJGB 3BCNA 1O0EA 3F75A 2DC6A 1A6RA 1CSBB 3BPFA 3H8BA 2FE8A 1AYWA 4REZA 1GECE 4ZUXU 3N3GA 3PRMA 1THEA 2ARYA 4X6JA 1F2BA 1MEMA 3ERVA 3RVXA 2NQGA 3M99A 3BWKA 2BTWB 3ZUAA 4CDEB 2DC8A 1ZCMA 4P6GA 1GMYA 1DKIA 2UZJA 2DCAA 3H8CA 3I06A 4MI7A 4BQVA 4W5CA 4MSXA 4QRXA 2AVWA 4Q8GA 4A5UA 4YYQA 3B21A 4MZSA 4D8EA 4N4ZA 1JQPA 5KO3A 1KHPA 3HHIA 6PADA 4DMXA 4N79A 3B79A 2FYEA 3HHAA 2FUDA 4PADA 1ZIVA 1M6DA 3PDFA 5EZQA 1PPOA 4BS6A 1ME3A 4RF1A 1EF7A 4I04A 1ATKA 3K8UA 1CPJA 2CIOA 2FO5A 2VHFA 1PCIA 1STFE 2IBIA 5FPWA 1AU3A 1NPZA 2AIMA 2JTCA 3BY4A 4PP1A 1U9VA 2GFOA 4CDCB 4HWYA 2J7QC 3HD3A 1BP4A 4W4UA 2DCDA 3WXFA 9PAPA 1Q6KA 5JZEA 3BB7A 4G54A 3OVZA 4PT5A 5F02A
chains in the Genus database with same CATH topology
1PPNA 3P5VA 4Q8HA 1NQCA 2YJ2A 2G6DA 1CQDA 2Y6EA 2R9FA 3S3QA 1SP4B 3D9WA 3KX1A 1EWOA 4QRVA 3KKUA 1ME4A 2FT2A 3LFYA 1CVZA 4OELA 3NHEA 1BQIA 2NQDB 2FQ9A 1AU0A 2G8JA 2VFBA 4FJCA 2JQGR 4AXLA 2VFCA 2YJCA 3V6EA 4NV8A 4PI3A 1AYUA 1F2CA 3MTNA 1CB5A 1YALA 4QBBA 2C0YA 2YJBA 3OF8A 1TU6A 3P5UA 1CTEA 1YT7A 1PPDA 1W5RA 3F5VA 1AU2A 1PADA 3WXEA 2P86A 1MDWA 3WXGA 2DC7A 5PADA 5K16A 2DJFB 2AUZA 2XU3A 1ITOA 1MS6A 2DC9A 1YK8A 2HH5A 1KXRA 1VSNA 4CZWA 1NB3A 3CBJA 3PW3A 2F1GA 3BOWA 2Y5BA 4QRGA 4YYUA 1AIMA 3OF9A 1QMYA 3IEJA 3KWBX 2PREA 1U9XA 1KHQA 4PP2E 1QOLA 1VJVA 2OULA 1CS8A 2PADA 8PCHA 2PBHA 2DZZA 2AUXA 2BSZA 1YVBA 2DCCA 1KFUL 1DEUA 4MZOA 1HUCB 3H7DA 5EGWA 4WA6A 2WBFX 3K24A 4YYSA 3U8EA 1Y08A 7PCKA 3K9MA 4FK5A 3S3RA 3KSEA 4K7CA 5JA7A 1PBHA 4I05A 4YVAA 1BGOA 2BDLA 2YJ8A 5J94A 3USVA 2GHUA 4X6IA 2XU1A 2R9NA 2E02A 3GCBA 4XR7A 2F7DA 4XUIA 3PBHA 1NB5A 1CV8A 2G8EA 3KW9A 2H7JA 1W4TA 5EF4A 1X9YA 3N3KA 2B1MA 1PIPA 3P5WA 2BDZA 3OVXA 3LXSA 4B55A 3IHPA 1XKGA 1W6FA 3BPMA 1NL6A 2AU1A 2P7UA 2E00A 5CVOB 2DCBA 3QT4A 5CVNB 4DMYA 2R9CA 2P0RA 2VHSA 3BC3A 4YV8A 1QDQA 1GLOA 5CHVA 4YYRA 3PNRA 4QH6A 3RVWA 1EWMA 5CVMA 1GX3A 1U9WA 2HD5A 3OISA 3RVVA 3CBKA 4AXMA 1AU4A 3IOQA 1BY8A 1KFXL 1SNKA 3KFQA 2NQIA 2B1NA 2CB5A 5A24A 3LTWA 4N8WA 4YYWA 2AYNA 3QJ3A 2R9OA 1Y4HA 1IWDA 2G7YA 1MIRA 1AYVA 3KWZA 5CHTA 4YYVA 3D6SA 4BPVA 3IV2A 4FIPA 1EWLA 1GCBA 2AYOA 1MEGA 3MHHA 1EWPA 2HXZA 3O1GA 4RY2A 1YK7A 1DF0A 1PE6A 4BSQA 2R6NA 3AI8A 2R9MA 4I07A 2PNSA 3QSDA 1K3BB 2E03A 3H89A 3CH2X 2ACTA 1AECA 4KLBA 4NV7A 3MHSA 4BS5A 1F29A 1POPA 2IPPB 1ICFA 2E01A 1S4VA 2NQAA 3H6SA 3C9EA 3V6CA 2JQFR 2FRAA 1U9QX 2O6XA 3DF0A 3HWNA 2ATOA 4W5BA 3MORA 5JH3A 2OZ2A 2FTDA 4C5PA 3CH3X 1PPPA 1TLOA 3I3TA 3N4CA 3IMAA 2FRQA 1PXVA 2OP3A 4P6EA 1TL9A 1FH0A 3P5XA 4OEMA 2YJ9A 3TNXA 2DZYA 2HHNA 2XU4A 3E1ZB 2AS8A 1F2AA 4CDDB 4CDFB 1CJLA 1NLJA 1QXPA 4X6HA 1MHWA 2XU5A 4GUZA 1U5IA 3IUTA 3O0UA 2DJGB 3BCNA 1O0EA 3F75A 2DC6A 1A6RA 1CSBB 3BPFA 3H8BA 1AYWA 1GECE 4ZUXU 3N3GA 1THEA 2ARYA 4X6JA 1F2BA 1MEMA 3ERVA 3RVXA 2NQGA 3M99A 3BWKA 3ZUAA 4CDEB 2DC8A 1ZCMA 4P6GA 1GMYA 4BGFA 2DCAA 3H8CA 3I06A 4BQVA 4W5CA 4MSXA 4QRXA 2AVWA 4Q8GA 4YYQA 4MZSA 4N4ZA 1JQPA 1KHPA 3HHIA 6PADA 4DMXA 4N79A 3B79A 2FYEA 3HHAA 2FUDA 4PADA 1ZIVA 1E2TA 1M6DA 3PDFA 1PPOA 4BS6A 1ME3A 1EF7A 4I04A 1ATKA 3K8UA 1CPJA 2CIOA 2FO5A 2VHFA 1PCIA 1STFE 5FPWA 2IBIA 1AU3A 1NPZA 2AIMA 4PP1A 1U9VA 2GFOA 4CDCB 4HWYA 3HD3A 1BP4A 4W4UA 2DCDA 3WXFA 9PAPA 1Q6KA 4G54A 3OVZA 5F02A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PPN A;  3P5V A;  4Q8H A;  1NQC A;  2YJ2 A;  2G6D A;  1CQD A;  2Y6E A;  2R9F A;  3S3Q A;  1SP4 B;  3KX1 A;  1EWO A;  4QRV A;  3KKU A;  1ME4 A;  2FT2 A;  3LFY A;  1CVZ A;  4OEL A;  3NHE A;  1BQI A;  2NQD B;  2FQ9 A;  1AU0 A;  2G8J A;  4FJC A;  2JQG R;  4AXL A;  2YJC A;  3V6E A;  4PI3 A;  1AYU A;  1F2C A;  3MTN A;  1CB5 A;  1YAL A;  4QBB A;  2C0Y A;  2YJB A;  3OF8 A;  1TU6 A;  3P5U A;  1CTE A;  1YT7 A;  1PPD A;  3F5V A;  1AU2 A;  1PAD A;  3WXE A;  2P86 A;  1MDW A;  3WXG A;  2DC7 A;  5PAD A;  5K16 A;  2DJF B;  2AUZ A;  2XU3 A;  1ITO A;  1MS6 A;  2DC9 A;  1YK8 A;  2HH5 A;  1KXR A;  1VSN A;  4CZW A;  1NB3 A;  3CBJ A;  3PW3 A;  2F1G A;  3BOW A;  2Y5B A;  4QRG A;  4YYU A;  1AIM A;  3OF9 A;  1QMY A;  3IEJ A;  3KWB X;  2PRE A;  1U9X A;  1KHQ A;  4PP2 E;  1QOL A;  1VJV A;  2OUL A;  1CS8 A;  2PAD A;  8PCH A;  2PBH A;  2DZZ A;  2AUX A;  1YVB A;  2DCC A;  1KFU L;  1DEU A;  4MZO A;  1HUC B;  3H7D A;  5EGW A;  4WA6 A;  2WBF X;  3K24 A;  4YYS A;  3U8E A;  1Y08 A;  7PCK A;  3K9M A;  4FK5 A;  3S3R A;  3KSE A;  4K7C A;  5JA7 A;  1PBH A;  4I05 A;  4YVA A;  1BGO A;  2BDL A;  2YJ8 A;  5J94 A;  3USV A;  2GHU A;  4X6I A;  2XU1 A;  2R9N A;  2E02 A;  3GCB A;  4XR7 A;  2F7D A;  4XUI A;  3PBH A;  1NB5 A;  1CV8 A;  2G8E A;  3KW9 A;  2H7J A;  5EF4 A;  1X9Y A;  3N3K A;  2B1M A;  1PIP A;  3P5W A;  2BDZ A;  3OVX A;  3LXS A;  3IHP A;  1XKG A;  3BPM A;  1NL6 A;  2AU1 A;  2P7U A;  2E00 A;  5CVO B;  2DCB A;  3QT4 A;  5CVN B;  4DMY A;  2R9C A;  2P0R A;  2VHS A;  3BC3 A;  4YV8 A;  1QDQ A;  1GLO A;  5CHV A;  4YYR A;  3PNR A;  4QH6 A;  3RVW A;  1EWM A;  5CVM A;  1U9W A;  2HD5 A;  3OIS A;  3RVV A;  3CBK A;  4AXM A;  1AU4 A;  3IOQ A;  1BY8 A;  1KFX L;  1SNK A;  3KFQ A;  2NQI A;  2B1N A;  2CB5 A;  5A24 A;  4N8W A;  4YYW A;  2AYN A;  3QJ3 A;  2R9O A;  1Y4H A;  1IWD A;  2G7Y A;  1MIR A;  1AYV A;  3KWZ A;  5CHT A;  4YYV A;  3D6S A;  4BPV A;  3IV2 A;  4FIP A;  1EWL A;  1GCB A;  2AYO A;  1MEG A;  3MHH A;  1EWP A;  2HXZ A;  3O1G A;  4RY2 A;  1YK7 A;  1DF0 A;  1PE6 A;  4BSQ A;  2R6N A;  3AI8 A;  2R9M A;  4I07 A;  2PNS A;  3QSD A;  1K3B B;  2E03 A;  3H89 A;  3CH2 X;  2ACT A;  1AEC A;  4KLB A;  3MHS A;  4BS5 A;  1F29 A;  1POP A;  2IPP B;  1ICF A;  2E01 A;  1S4V A;  2NQA A;  3H6S A;  3C9E A;  3V6C A;  2JQF R;  2FRA A;  1U9Q X;  2O6X A;  3DF0 A;  3HWN A;  2ATO A;  4W5B A;  3MOR A;  5JH3 A;  2OZ2 A;  2FTD A;  3CH3 X;  1PPP A;  1TLO A;  3I3T A;  3N4C A;  3IMA A;  2FRQ A;  1PXV A;  2OP3 A;  4P6E A;  1TL9 A;  1FH0 A;  3P5X A;  4OEM A;  2YJ9 A;  3TNX A;  2DZY A;  2HHN A;  2XU4 A;  3E1Z B;  2AS8 A;  1F2A A;  4CDD B;  4CDF B;  1CJL A;  1NLJ A;  1QXP A;  4X6H A;  1MHW A;  2XU5 A;  1U5I A;  3IUT A;  3O0U A;  2DJG B;  3BCN A;  1O0E A;  3F75 A;  2DC6 A;  1A6R A;  1CSB B;  3BPF A;  3H8B A;  1AYW A;  1GEC E;  4ZUX U;  3N3G A;  1THE A;  2ARY A;  4X6J A;  1F2B A;  1MEM A;  3ERV A;  3RVX A;  2NQG A;  3M99 A;  3BWK A;  3ZUA A;  4CDE B;  2DC8 A;  1ZCM A;  4P6G A;  1GMY A;  2DCA A;  3H8C A;  3I06 A;  4BQV A;  4W5C A;  4MSX A;  4QRX A;  2AVW A;  4Q8G A;  4YYQ A;  4MZS A;  4N4Z A;  1JQP A;  1KHP A;  3HHI A;  6PAD A;  4DMX A;  4N79 A;  3B79 A;  2FYE A;  3HHA A;  2FUD A;  4PAD A;  1ZIV A;  1M6D A;  3PDF A;  1PPO A;  4BS6 A;  1ME3 A;  1EF7 A;  4I04 A;  1ATK A;  3K8U A;  1CPJ A;  2CIO A;  2FO5 A;  2VHF A;  1PCI A;  1STF E;  5FPW A;  2IBI A;  1AU3 A;  1NPZ A;  2AIM A;  4PP1 A;  1U9V A;  2GFO A;  4CDC B;  4HWY A;  3HD3 A;  1BP4 A;  4W4U A;  2DCD A;  3WXF A;  9PAP A;  1Q6K A;  4G54 A;  3OVZ A;  5F02 A; 
#chains in the Genus database with same CATH topology
 4BOQ A;  1PPN A;  3P5V A;  3RNV A;  4Q8H A;  3MTV A;  1NQC A;  2YJ2 A;  2G6D A;  1CQD A;  2BU3 A;  2Y6E A;  2R9F A;  3S3Q A;  1SP4 B;  3KX1 A;  1EWO A;  3PHW A;  3TRK A;  4QRV A;  3KKU A;  1ME4 A;  2FT2 A;  5E6J A;  3LFY A;  1CVZ A;  3O65 A;  4OEL A;  3NHE A;  1BQI A;  2NQD B;  2FQ9 A;  3TMP A;  1AU0 A;  2G8J A;  4FJC A;  2JQG R;  4AXL A;  2YJC A;  4OVZ B;  3MP2 A;  3V6E A;  4D8B A;  2DOS A;  4PI3 A;  1AYU A;  1F2C A;  3MTN A;  1CB5 A;  1YAL A;  3PHX A;  1UKF A;  4QBB A;  2C0Y A;  3W31 A;  2YJB A;  3OF8 A;  1TU6 A;  3P5U A;  1CTE A;  1YT7 A;  1PPD A;  3F5V A;  1AU2 A;  1PAD A;  3WXE A;  2P86 A;  1MDW A;  3WXG A;  4P16 A;  2DC7 A;  5PAD A;  1PVJ A;  5K16 A;  2DJF B;  2AUZ A;  2XU3 A;  1ITO A;  1MS6 A;  2DC9 A;  1YK8 A;  2HH5 A;  1KXR A;  1VSN A;  4CZW A;  1NB3 A;  3CBJ A;  3PW3 A;  2F1G A;  3BOW A;  2Y5B A;  4QRG A;  4YYU A;  3ZNH A;  1AIM A;  3OF9 A;  1QMY A;  3IEJ A;  3KWB X;  2PRE A;  1U9X A;  1KHQ A;  4PP2 E;  1QOL A;  1VJV A;  2OUL A;  1CS8 A;  2PAD A;  8PCH A;  2PBH A;  2DZZ A;  2AUX A;  1YVB A;  2DCC A;  1KFU L;  1DEU A;  4MZO A;  1HUC B;  3H7D A;  5EGW A;  5EZS A;  2HWK A;  4WA6 A;  2WBF X;  3K24 A;  4YYS A;  3U8E A;  1Y08 A;  7PCK A;  2JRI A;  4BOZ A;  3K9M A;  4FK5 A;  3S3R A;  3KSE A;  4K7C A;  4BOS A;  3MJ5 A;  5JA7 A;  1PBH A;  4I05 A;  3PT2 A;  4YVA A;  1BGO A;  2BDL A;  2YJ8 A;  3C0R A;  5J94 A;  3USV A;  4GUA A;  2GHU A;  4X6I A;  4D8I A;  2XU1 A;  2R9N A;  2E02 A;  3GCB A;  4XR7 A;  2F7D A;  4XUI A;  2J7Q A;  3PBH A;  1NB5 A;  1CV8 A;  2G8E A;  3IFU A;  3KW9 A;  2H7J A;  3PSE A;  5EF4 A;  1X9Y A;  3N3K A;  2B1M A;  1PIP A;  3P5W A;  2BDZ A;  4M0W A;  3OVX A;  3LXS A;  3IHP A;  1XKG A;  4BOU A;  4MM3 B;  3BPM A;  4IP3 A;  1NL6 A;  2AU1 A;  2P7U A;  2E00 A;  5CVO B;  2DCB A;  3QT4 A;  5CVN B;  4DMY A;  2R9C A;  2P0R A;  2VHS A;  3BC3 A;  4YV8 A;  1QDQ A;  1GLO A;  5CHV A;  4YYR A;  3PNR A;  4XZX A;  4QH6 A;  3RVW A;  1EWM A;  5CVM A;  1U9W A;  2HD5 A;  3OIS A;  3W30 A;  3RVV A;  3CBK A;  4AXM A;  1AU4 A;  3IOQ A;  4RKX A;  1BY8 A;  4R3D A;  4IUM A;  1KFX L;  1SNK A;  3KFQ A;  2NQI A;  2B1N A;  2CB5 A;  5A24 A;  4N8W A;  3E9S A;  4YYW A;  2AYN A;  3QJ3 A;  2R9O A;  1Y4H A;  1IWD A;  2G7Y A;  1MIR A;  1AYV A;  3KWZ A;  5CHT A;  4YYV A;  3D6S A;  4BPV A;  3IV2 A;  4FIP A;  1EWL A;  1GCB A;  2AYO A;  1MEG A;  3MHH A;  4OW0 A;  1EWP A;  2HXZ A;  3O1G A;  4RY2 A;  1YK7 A;  1DF0 A;  1PE6 A;  4BSQ A;  2R6N A;  4ZTB A;  3AI8 A;  4HXD B;  2R9M A;  4I07 A;  2PNS A;  3OQC A;  3QSD A;  1K3B B;  2E03 A;  2AGA A;  3CH2 X;  3H89 A;  2ACT A;  1AEC A;  4KLB A;  3MHS A;  4OVZ A;  4BS5 A;  1F29 A;  1POP A;  2IPP B;  1ICF A;  2E01 A;  1S4V A;  2NQA A;  3H6S A;  3C9E A;  3V6C A;  2JQF R;  1YZB A;  3PHU A;  2FRA A;  1U9Q X;  2O6X A;  3DF0 A;  3PRP A;  3HWN A;  2ATO A;  4W5B A;  4RNA A;  3MOR A;  5JH3 A;  2OZ2 A;  2FTD A;  3CH3 X;  1PPP A;  1TLO A;  3I3T A;  3N4C A;  3IMA A;  2FRQ A;  1PXV A;  2OP3 A;  4WUR A;  3BBA A;  4BOP A;  4P6E A;  1TL9 A;  2BTW A;  1FH0 A;  3P5X A;  4OEM A;  2YJ9 A;  3TNX A;  2DZY A;  2HHN A;  2XU4 A;  4RF0 A;  3E1Z B;  2AS8 A;  1F2A A;  4CDD B;  2Z84 A;  4CDF B;  1CJL A;  1NLJ A;  1QXP A;  4X6H A;  1MHW A;  2XU5 A;  1U5I A;  3IUT A;  3O0U A;  2DJG B;  3BCN A;  1O0E A;  3F75 A;  2DC6 A;  1A6R A;  1CSB B;  3BPF A;  3H8B A;  2FE8 A;  1AYW A;  4REZ A;  1GEC E;  4ZUX U;  3N3G A;  3PRM A;  1THE A;  2ARY A;  4X6J A;  1F2B A;  1MEM A;  3ERV A;  3RVX A;  2NQG A;  3M99 A;  3BWK A;  2BTW B;  3ZUA A;  4CDE B;  2DC8 A;  1ZCM A;  4P6G A;  1GMY A;  1DKI A;  2UZJ A;  2DCA A;  3H8C A;  3I06 A;  4MI7 A;  4BQV A;  4W5C A;  4MSX A;  4QRX A;  2AVW A;  4Q8G A;  4A5U A;  4YYQ A;  3B21 A;  4MZS A;  4D8E A;  4N4Z A;  1JQP A;  5KO3 A;  1KHP A;  3HHI A;  6PAD A;  4DMX A;  4N79 A;  3B79 A;  2FYE A;  3HHA A;  2FUD A;  4PAD A;  1ZIV A;  1M6D A;  3PDF A;  5EZQ A;  1PPO A;  4BS6 A;  1ME3 A;  4RF1 A;  1EF7 A;  4I04 A;  1ATK A;  3K8U A;  1CPJ A;  2CIO A;  2FO5 A;  2VHF A;  1PCI A;  1STF E;  2IBI A;  5FPW A;  1AU3 A;  1NPZ A;  2AIM A;  2JTC A;  3BY4 A;  4PP1 A;  1U9V A;  2GFO A;  4CDC B;  4HWY A;  2J7Q C;  3HD3 A;  1BP4 A;  4W4U A;  2DCD A;  3WXF A;  9PAP A;  1Q6K A;  5JZE A;  3BB7 A;  4G54 A;  3OVZ A;  4PT5 A;  5F02 A; 
#chains in the Genus database with same CATH homology
 1PPN A;  3P5V A;  4Q8H A;  1NQC A;  2YJ2 A;  2G6D A;  1CQD A;  2Y6E A;  2R9F A;  3S3Q A;  1SP4 B;  3D9W A;  3KX1 A;  1EWO A;  4QRV A;  3KKU A;  1ME4 A;  2FT2 A;  3LFY A;  1CVZ A;  4OEL A;  3NHE A;  1BQI A;  2NQD B;  2FQ9 A;  1AU0 A;  2G8J A;  2VFB A;  4FJC A;  2JQG R;  4AXL A;  2VFC A;  2YJC A;  3V6E A;  4NV8 A;  4PI3 A;  1AYU A;  1F2C A;  3MTN A;  1CB5 A;  1YAL A;  4QBB A;  2C0Y A;  2YJB A;  3OF8 A;  1TU6 A;  3P5U A;  1CTE A;  1YT7 A;  1PPD A;  1W5R A;  3F5V A;  1AU2 A;  1PAD A;  3WXE A;  2P86 A;  1MDW A;  3WXG A;  2DC7 A;  5PAD A;  5K16 A;  2DJF B;  2AUZ A;  2XU3 A;  1ITO A;  1MS6 A;  2DC9 A;  1YK8 A;  2HH5 A;  1KXR A;  1VSN A;  4CZW A;  1NB3 A;  3CBJ A;  3PW3 A;  2F1G A;  3BOW A;  2Y5B A;  4QRG A;  4YYU A;  1AIM A;  3OF9 A;  1QMY A;  3IEJ A;  3KWB X;  2PRE A;  1U9X A;  1KHQ A;  4PP2 E;  1QOL A;  1VJV A;  2OUL A;  1CS8 A;  2PAD A;  8PCH A;  2PBH A;  2DZZ A;  2AUX A;  2BSZ A;  1YVB A;  2DCC A;  1KFU L;  1DEU A;  4MZO A;  1HUC B;  3H7D A;  5EGW A;  4WA6 A;  2WBF X;  3K24 A;  4YYS A;  3U8E A;  1Y08 A;  7PCK A;  3K9M A;  4FK5 A;  3S3R A;  3KSE A;  4K7C A;  5JA7 A;  1PBH A;  4I05 A;  4YVA A;  1BGO A;  2BDL A;  2YJ8 A;  5J94 A;  3USV A;  2GHU A;  4X6I A;  2XU1 A;  2R9N A;  2E02 A;  3GCB A;  4XR7 A;  2F7D A;  4XUI A;  3PBH A;  1NB5 A;  1CV8 A;  2G8E A;  3KW9 A;  2H7J A;  1W4T A;  5EF4 A;  1X9Y A;  3N3K A;  2B1M A;  1PIP A;  3P5W A;  2BDZ A;  3OVX A;  3LXS A;  4B55 A;  3IHP A;  1XKG A;  1W6F A;  3BPM A;  1NL6 A;  2AU1 A;  2P7U A;  2E00 A;  5CVO B;  2DCB A;  3QT4 A;  5CVN B;  4DMY A;  2R9C A;  2P0R A;  2VHS A;  3BC3 A;  4YV8 A;  1QDQ A;  1GLO A;  5CHV A;  4YYR A;  3PNR A;  4QH6 A;  3RVW A;  1EWM A;  5CVM A;  1GX3 A;  1U9W A;  2HD5 A;  3OIS A;  3RVV A;  3CBK A;  4AXM A;  1AU4 A;  3IOQ A;  1BY8 A;  1KFX L;  1SNK A;  3KFQ A;  2NQI A;  2B1N A;  2CB5 A;  5A24 A;  3LTW A;  4N8W A;  4YYW A;  2AYN A;  3QJ3 A;  2R9O A;  1Y4H A;  1IWD A;  2G7Y A;  1MIR A;  1AYV A;  3KWZ A;  5CHT A;  4YYV A;  3D6S A;  4BPV A;  3IV2 A;  4FIP A;  1EWL A;  1GCB A;  2AYO A;  1MEG A;  3MHH A;  1EWP A;  2HXZ A;  3O1G A;  4RY2 A;  1YK7 A;  1DF0 A;  1PE6 A;  4BSQ A;  2R6N A;  3AI8 A;  2R9M A;  4I07 A;  2PNS A;  3QSD A;  1K3B B;  2E03 A;  3H89 A;  3CH2 X;  2ACT A;  1AEC A;  4KLB A;  4NV7 A;  3MHS A;  4BS5 A;  1F29 A;  1POP A;  2IPP B;  1ICF A;  2E01 A;  1S4V A;  2NQA A;  3H6S A;  3C9E A;  3V6C A;  2JQF R;  2FRA A;  1U9Q X;  2O6X A;  3DF0 A;  3HWN A;  2ATO A;  4W5B A;  3MOR A;  5JH3 A;  2OZ2 A;  2FTD A;  4C5P A;  3CH3 X;  1PPP A;  1TLO A;  3I3T A;  3N4C A;  3IMA A;  2FRQ A;  1PXV A;  2OP3 A;  4P6E A;  1TL9 A;  1FH0 A;  3P5X A;  4OEM A;  2YJ9 A;  3TNX A;  2DZY A;  2HHN A;  2XU4 A;  3E1Z B;  2AS8 A;  1F2A A;  4CDD B;  4CDF B;  1CJL A;  1NLJ A;  1QXP A;  4X6H A;  1MHW A;  2XU5 A;  4GUZ A;  1U5I A;  3IUT A;  3O0U A;  2DJG B;  3BCN A;  1O0E A;  3F75 A;  2DC6 A;  1A6R A;  1CSB B;  3BPF A;  3H8B A;  1AYW A;  1GEC E;  4ZUX U;  3N3G A;  1THE A;  2ARY A;  4X6J A;  1F2B A;  1MEM A;  3ERV A;  3RVX A;  2NQG A;  3M99 A;  3BWK A;  3ZUA A;  4CDE B;  2DC8 A;  1ZCM A;  4P6G A;  1GMY A;  4BGF A;  2DCA A;  3H8C A;  3I06 A;  4BQV A;  4W5C A;  4MSX A;  4QRX A;  2AVW A;  4Q8G A;  4YYQ A;  4MZS A;  4N4Z A;  1JQP A;  1KHP A;  3HHI A;  6PAD A;  4DMX A;  4N79 A;  3B79 A;  2FYE A;  3HHA A;  2FUD A;  4PAD A;  1ZIV A;  1E2T A;  1M6D A;  3PDF A;  1PPO A;  4BS6 A;  1ME3 A;  1EF7 A;  4I04 A;  1ATK A;  3K8U A;  1CPJ A;  2CIO A;  2FO5 A;  2VHF A;  1PCI A;  1STF E;  5FPW A;  2IBI A;  1AU3 A;  1NPZ A;  2AIM A;  4PP1 A;  1U9V A;  2GFO A;  4CDC B;  4HWY A;  3HD3 A;  1BP4 A;  4W4U A;  2DCD A;  3WXF A;  9PAP A;  1Q6K A;  4G54 A;  3OVZ A;  5F02 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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