2YJ2A

Cathepsin l with a nitrile inhibitor
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
220
structure length
219
Chain Sequence
b'APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTSDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords CATHEPSIN L1
publication title Halogen Bonding at the Active Sites of Human Cathepsin L and Mek1 Kinase: Efficient Interactions in Different Environments.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 72
structure length 219
sequence length 220
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2011-05-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2yj2A00
1F2CA 2PNSA 1QXPA 2WBFX 3OVZA 4WA6A 2NQGA 4XUIA 2JQFR 4W4UA 2PREA 3KWZA 3LXSA 5JA7A 2YJ2A 3E1ZB 1EWOA 3MTNA 1CV8A 3N4CA 3BPMA 1POPA 1X9YA 2E02A 4QRVA 4YVAA 2P0RA 4N4ZA 2R9FA 5EF4A 1NL6A 3CH2X 3N3GA 1AU4A 7PCKA 5EGWA 3F5VA 1IWDA 1TL9A 4W5BA 1U9WA 2DC9A 3P5WA 1AU3A 3ERVA 2BDLA 2E00A 1CB5A 2CIOA 4BPVA 1ICFA 1VJVA 3IHPA 3B79A 1TLOA 2DCAA 3MHSA 3OVXA 1F2AA 2AYOA 1U9VA 2G8JA 1YK8A 3O0UA 2E01A 1CS8A 1M6DA 1JQPA 3F75A 4I07A 4X6IA 4OELA 2DZZA 4OEMA 4I05A 5FPWA 1MEMA 5J94A 3QJ3A 1YK7A 3H89A 2PBHA 3IV2A 3OF8A 1PCIA 1BGOA 3V6CA 1EWPA 4AXLA 3H8CA 3IMAA 3H7DA 1O0EA 3U8EA 2AUZA 2AUXA 1THEA 2R9NA 2NQIA 2AU1A 2F1GA 1ZCMA 2FUDA 1PXVA 2R9MA 4YYUA 1MS6A 4YYSA 4Q8GA 1PBHA 2CB5A 3P5VA 1QMYA 1ZIVA 2F7DA 4DMYA 2XU3A 1NQCA 3BOWA 3HWNA 2DCBA 3ZUAA 2FRQA 1CJLA 1SNKA 2IPPB 1U5IA 3NHEA 5A24A 5CVMA 3PBHA 3O1GA 1CVZA 2DCDA 1PPDA 3KKUA 8PCHA 3K24A 1F29A 1U9QX 2OP3A 2FT2A 4K7CA 3PDFA 3K8UA 1BY8A 1EF7A 1MHWA 4FK5A 2AYNA 1EWLA 3BPFA 4AXMA 1AECA 2NQDB 2ACTA 1CTEA 2GHUA 2R9CA 2Y6EA 2IBIA 4CZWA 1F2BA 3V6EA 1GECE 4N8WA 1MDWA 3QT4A 4PP1A 1Y4HA 4BQVA 1KHQA 1KFXL 3KWBX 1VSNA 5CVOB 3GCBA 4W5CA 2FYEA 3I3TA 1AIMA 4CDDB 4QBBA 1S4VA 2XU1A 2FO5A 4XR7A 3OF9A 4ZUXU 1AU0A 1GLOA 4G54A 3USVA 2DCCA 3AI8A 2GFOA 3HHIA 2P7UA 1ME4A 3PNRA 5F02A 1MIRA 3WXEA 5K16A 3C9EA 2JQGR 4MZOA 2R9OA 2FTDA 2HH5A 3OISA 4QH6A 2R6NA 2ATOA 4X6JA 4YYRA 9PAPA 3LFYA 2E03A 3M99A 3WXFA 4P6EA 4MSXA 1SP4B 4BS5A 3S3RA 2OZ2A 1HUCB 3MHHA 2AS8A 2DJFB 4Q8HA 1Y08A 4YYQA 3IOQA 2FQ9A 1Q6KA 5CVNB 1MEGA 1PPPA 2DC6A 2PADA 3DF0A 4BSQA 1CQDA 2XU4A 2YJ8A 3TNXA 6PADA 1DF0A 1ITOA 4FJCA 4N79A 4RY2A 1XKGA 1EWMA 5JH3A 3BC3A 4BS6A 4P6GA 4CDCB 3KW9A 1U9XA 3HD3A 1KHPA 2HHNA 5PADA 2G8EA 3KX1A 5CHVA 3PW3A 3IEJA 2G7YA 3K9MA 2ARYA 3H8BA 1NPZA 4I04A 3KSEA 2YJ9A 3H6SA 3WXGA 4CDEB 4PADA 1BP4A 3IUTA 3I06A 1YT7A 1DEUA 1KFUL 4PI3A 1STFE 4CDFB 2DJGB 1AYWA 4YV8A 4QRXA 1FH0A 2VHFA 1TU6A 2OULA 4FIPA 1PIPA 1YALA 1PADA 2B1MA 3RVXA 1NB3A 4X6HA 2P86A 2YJCA 2NQAA 3CBJA 3BCNA 3P5XA 1PPNA 2O6XA 2FRAA 1BQIA 2YJBA 1CSBB 2AIMA 3BWKA 2DZYA 1AU2A 1NLJA 4PP2E 2C0YA 2BDZA 3S3QA 4YYWA 3CH3X 1ME3A 2DC7A 3P5UA 1AYVA 5CHTA 3RVVA 2G6DA 4DMXA 1A6RA 1NB5A 2H7JA 2B1NA 3QSDA 4QRGA 3HHAA 2Y5BA 1GCBA 1PE6A 1KXRA 1QDQA 4MZSA 2HXZA 2VHSA 4KLBA 2AVWA 4HWYA 3KFQA 1CPJA 1AYUA 4YYVA 3RVWA 1K3BB 2HD5A 3D6SA 1QOLA 1YVBA 3N3KA 1ATKA 1GMYA 3MORA 1PPOA 2DC8A 2XU5A 3CBKA
chains in the Genus database with same CATH superfamily
3PT2A 1F2CA 2PNSA 1QXPA 4PT5A 2WBFX 3OVZA 4WA6A 2NQGA 4XUIA 2JQFR 4W4UA 2PREA 3KWZA 3LXSA 5JA7A 2YJ2A 3E1ZB 1EWOA 3MTNA 1CV8A 3N4CA 3BPMA 4OVZB 1POPA 4BOPA 1X9YA 2E02A 4QRVA 4YVAA 2P0RA 4N4ZA 2R9FA 5EF4A 2BTWB 1NL6A 3CH2X 3N3GA 1AU4A 7PCKA 5EGWA 3F5VA 1IWDA 1TL9A 4W5BA 1U9WA 2DC9A 3P5WA 1AU3A 3ERVA 2BDLA 2E00A 1CB5A 2CIOA 4BPVA 1ICFA 1VJVA 4RF1A 3IHPA 3B79A 1TLOA 2DCAA 3MHSA 3OVXA 1F2AA 2AYOA 4P16A 2HWKA 1U9VA 2G8JA 1YK8A 4A5UA 3O0UA 2E01A 1CS8A 1M6DA 1JQPA 3F75A 4I07A 4X6IA 4OELA 2DZZA 4OEMA 4I05A 5FPWA 1MEMA 5J94A 3MJ5A 4BOZA 3QJ3A 1YK7A 3H89A 1UKFA 2PBHA 3IV2A 3OF8A 1PCIA 1BGOA 3V6CA 1EWPA 2Z84A 4AXLA 3H8CA 3IMAA 3H7DA 1O0EA 3U8EA 2AUZA 2AUXA 1THEA 2R9NA 3OQCA 2NQIA 3BB7A 2AU1A 2F1GA 1ZCMA 2FUDA 1PXVA 2R9MA 4YYUA 1MS6A 4YYSA 4Q8GA 1PBHA 2DOSA 2CB5A 3P5VA 5E6JA 1QMYA 4ZTBA 1ZIVA 2F7DA 1YZBA 4DMYA 2XU3A 3PSEA 1NQCA 3BOWA 3HWNA 2DCBA 3ZUAA 2FRQA 1CJLA 3PHXA 1SNKA 2IPPB 3BBAA 1U5IA 3NHEA 5A24A 5CVMA 3PBHA 2UZJA 3O1GA 4IP3A 1CVZA 2DCDA 1PPDA 3KKUA 8PCHA 3K24A 4R3DA 1F29A 1PVJA 3MP2A 1U9QX 2OP3A 4OW0A 2FT2A 4K7CA 3TRKA 3PDFA 3K8UA 1BY8A 1EF7A 1MHWA 4FK5A 2AYNA 1EWLA 3B21A 3BPFA 3IFUA 4AXMA 1AECA 2NQDB 2ACTA 1CTEA 2GHUA 2R9CA 2Y6EA 2IBIA 4CZWA 3ZNHA 1F2BA 3V6EA 1GECE 3RNVA 2FE8A 4N8WA 1MDWA 4REZA 3QT4A 4PP1A 1Y4HA 4BQVA 1KHQA 3W30A 1KFXL 3KWBX 1VSNA 4RNAA 4HXDB 5CVOB 3GCBA 4W5CA 2FYEA 3I3TA 1AIMA 4CDDB 2BU3A 4QBBA 1S4VA 2XU1A 2FO5A 4RKXA 4XR7A 3OF9A 4ZUXU 1AU0A 5EZQA 1DKIA 5EZSA 4BOUA 3PRMA 1GLOA 4D8EA 4G54A 3USVA 2DCCA 3AI8A 2GFOA 3HHIA 2P7UA 1ME4A 3PNRA 5F02A 1MIRA 3PRPA 3WXEA 5K16A 3C9EA 5JZEA 2JQGR 3C0RA 4MZOA 2R9OA 2FTDA 2HH5A 3OISA 4QH6A 2R6NA 4BOSA 2ATOA 2JRIA 4X6JA 4YYRA 9PAPA 3LFYA 2E03A 3M99A 3WXFA 4P6EA 4MSXA 1SP4B 4BS5A 4BOQA 4IUMA 3S3RA 2OZ2A 1HUCB 3MHHA 4M0WA 2AS8A 2DJFB 4Q8HA 1Y08A 4YYQA 3IOQA 2FQ9A 1Q6KA 5CVNB 1MEGA 1PPPA 2DC6A 2PADA 2J7QA 3DF0A 4RF0A 3TMPA 3W31A 4BSQA 3MTVA 1CQDA 2XU4A 2YJ8A 3TNXA 6PADA 1DF0A 1ITOA 4FJCA 4N79A 4RY2A 1XKGA 1EWMA 5JH3A 3BC3A 4BS6A 4MM3B 4P6GA 4CDCB 3KW9A 1U9XA 3E9SA 3HD3A 1KHPA 2HHNA 5PADA 2G8EA 3KX1A 5CHVA 2AGAA 3IEJA 2G7YA 3PW3A 3K9MA 2ARYA 3H8BA 1NPZA 4I04A 4GUAA 3KSEA 2YJ9A 3H6SA 3WXGA 4CDEB 4PADA 1BP4A 3IUTA 3I06A 1YT7A 1DEUA 1KFUL 4PI3A 1STFE 3BY4A 4CDFB 4D8IA 2DJGB 1AYWA 3PHUA 4YV8A 4QRXA 1FH0A 2VHFA 2JTCA 1TU6A 2OULA 4FIPA 1PIPA 1YALA 1PADA 2B1MA 3RVXA 4D8BA 1NB3A 4X6HA 2P86A 2YJCA 2NQAA 3CBJA 3BCNA 3P5XA 1PPNA 2O6XA 2FRAA 1BQIA 2YJBA 1CSBB 5KO3A 2AIMA 3BWKA 2DZYA 1AU2A 1NLJA 4PP2E 2C0YA 4XZXA 2BDZA 3S3QA 4YYWA 3CH3X 1ME3A 4MI7A 4OVZA 2DC7A 3P5UA 1AYVA 3O65A 5CHTA 3RVVA 2G6DA 4DMXA 1A6RA 1NB5A 2H7JA 2B1NA 3QSDA 4QRGA 3HHAA 2BTWA 2Y5BA 1GCBA 1PE6A 1KXRA 1QDQA 4MZSA 2HXZA 2VHSA 4KLBA 3PHWA 2AVWA 4HWYA 3KFQA 1CPJA 1AYUA 4WURA 4YYVA 2J7QC 3RVWA 1K3BB 2HD5A 3D6SA 1QOLA 1YVBA 3N3KA 1ATKA 1GMYA 3MORA 1PPOA 2DC8A 2XU5A 3CBKA
chains in the Genus database with same CATH topology
1F2CA 2PNSA 1QXPA 2WBFX 3OVZA 4WA6A 2NQGA 4XUIA 2JQFR 4W4UA 2PREA 3KWZA 3LXSA 5JA7A 2YJ2A 3E1ZB 1EWOA 3MTNA 1CV8A 3N4CA 3BPMA 1POPA 1X9YA 2E02A 4QRVA 4YVAA 2P0RA 4N4ZA 2R9FA 5EF4A 1NL6A 3CH2X 3N3GA 1AU4A 7PCKA 4GUZA 5EGWA 3F5VA 1IWDA 1TL9A 2VFBA 4W5BA 1U9WA 2DC9A 3P5WA 1AU3A 3ERVA 2BDLA 2E00A 1CB5A 2CIOA 4BPVA 1ICFA 1VJVA 3IHPA 3B79A 1TLOA 2DCAA 3MHSA 3OVXA 1F2AA 2AYOA 1U9VA 2G8JA 1YK8A 1W4TA 3O0UA 2E01A 1CS8A 1M6DA 1JQPA 3F75A 4I07A 4X6IA 4OELA 2DZZA 4OEMA 4I05A 5FPWA 1MEMA 5J94A 4BGFA 3QJ3A 1YK7A 3H89A 2PBHA 3IV2A 3OF8A 1PCIA 1BGOA 3V6CA 1EWPA 4AXLA 3H8CA 3IMAA 3H7DA 1O0EA 3U8EA 2AUZA 2AUXA 1THEA 2R9NA 2NQIA 2AU1A 2F1GA 1ZCMA 2FUDA 1PXVA 2R9MA 4YYUA 1MS6A 4YYSA 2VFCA 4Q8GA 1PBHA 2CB5A 3P5VA 1QMYA 1ZIVA 2F7DA 4DMYA 2XU3A 1NQCA 3BOWA 3HWNA 2DCBA 3ZUAA 2FRQA 1CJLA 1SNKA 2IPPB 1U5IA 3NHEA 5A24A 5CVMA 3PBHA 3O1GA 1CVZA 2DCDA 1PPDA 3KKUA 8PCHA 3K24A 1F29A 1U9QX 2OP3A 2FT2A 4K7CA 3PDFA 3K8UA 4NV7A 1BY8A 1EF7A 1MHWA 4FK5A 2AYNA 1EWLA 3BPFA 4AXMA 1AECA 2NQDB 2ACTA 1CTEA 2GHUA 2R9CA 2Y6EA 2IBIA 4CZWA 1F2BA 3V6EA 1GECE 4N8WA 1MDWA 3QT4A 4PP1A 1Y4HA 4BQVA 1KHQA 1KFXL 3KWBX 1VSNA 5CVOB 3GCBA 4NV8A 4W5CA 2BSZA 2FYEA 3I3TA 1AIMA 4CDDB 4QBBA 1S4VA 2XU1A 2FO5A 4XR7A 3OF9A 4ZUXU 1AU0A 1GLOA 4G54A 3USVA 2DCCA 3AI8A 2GFOA 3HHIA 2P7UA 1ME4A 3PNRA 5F02A 1MIRA 3WXEA 5K16A 3C9EA 2JQGR 4MZOA 2R9OA 2FTDA 2HH5A 3OISA 4QH6A 2R6NA 2ATOA 4X6JA 4YYRA 9PAPA 3LFYA 2E03A 3M99A 3WXFA 3D9WA 4P6EA 4MSXA 1SP4B 4BS5A 3S3RA 2OZ2A 1HUCB 3MHHA 2AS8A 2DJFB 4Q8HA 1Y08A 4YYQA 3IOQA 2FQ9A 1GX3A 1Q6KA 5CVNB 1MEGA 1PPPA 2DC6A 2PADA 3DF0A 4BSQA 1CQDA 2XU4A 2YJ8A 3TNXA 6PADA 1DF0A 1ITOA 4FJCA 4N79A 4RY2A 1XKGA 1EWMA 5JH3A 3BC3A 4BS6A 4P6GA 4CDCB 3KW9A 1U9XA 3HD3A 1KHPA 2HHNA 5PADA 2G8EA 3KX1A 5CHVA 3PW3A 3IEJA 2G7YA 4B55A 3K9MA 1W5RA 2ARYA 3H8BA 1NPZA 4I04A 3KSEA 2YJ9A 1E2TA 3H6SA 3WXGA 4CDEB 4PADA 1BP4A 3IUTA 3I06A 1YT7A 1DEUA 1KFUL 4PI3A 1STFE 4CDFB 2DJGB 1AYWA 4YV8A 4QRXA 1FH0A 2VHFA 1TU6A 2OULA 4FIPA 1PIPA 1YALA 1PADA 2B1MA 3RVXA 1NB3A 4X6HA 2P86A 2YJCA 2NQAA 3CBJA 3BCNA 3P5XA 1PPNA 2O6XA 2FRAA 1BQIA 2YJBA 1CSBB 2AIMA 3BWKA 2DZYA 1AU2A 1NLJA 4PP2E 2C0YA 2BDZA 1W6FA 3LTWA 3S3QA 4YYWA 3CH3X 1ME3A 2DC7A 3P5UA 1AYVA 5CHTA 3RVVA 2G6DA 4DMXA 1A6RA 1NB5A 2H7JA 2B1NA 3QSDA 4QRGA 3HHAA 2Y5BA 1GCBA 1PE6A 1KXRA 1QDQA 4MZSA 2HXZA 2VHSA 4C5PA 4KLBA 2AVWA 4HWYA 3KFQA 1CPJA 1AYUA 4YYVA 3RVWA 1K3BB 2HD5A 3D6SA 1QOLA 1YVBA 3N3KA 1ATKA 1GMYA 3MORA 1PPOA 2DC8A 2XU5A 3CBKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1F2C A;  2PNS A;  1QXP A;  2WBF X;  3OVZ A;  4WA6 A;  2NQG A;  4XUI A;  2JQF R;  4W4U A;  2PRE A;  3KWZ A;  3LXS A;  5JA7 A;  2YJ2 A;  3E1Z B;  1EWO A;  3MTN A;  1CV8 A;  3N4C A;  3BPM A;  1POP A;  1X9Y A;  2E02 A;  4QRV A;  4YVA A;  2P0R A;  4N4Z A;  2R9F A;  5EF4 A;  1NL6 A;  3CH2 X;  3N3G A;  1AU4 A;  7PCK A;  5EGW A;  3F5V A;  1IWD A;  1TL9 A;  4W5B A;  1U9W A;  2DC9 A;  3P5W A;  1AU3 A;  3ERV A;  2BDL A;  2E00 A;  1CB5 A;  2CIO A;  4BPV A;  1ICF A;  1VJV A;  3IHP A;  3B79 A;  1TLO A;  2DCA A;  3MHS A;  3OVX A;  1F2A A;  2AYO A;  1U9V A;  2G8J A;  1YK8 A;  3O0U A;  2E01 A;  1CS8 A;  1M6D A;  1JQP A;  3F75 A;  4I07 A;  4X6I A;  4OEL A;  2DZZ A;  4OEM A;  4I05 A;  5FPW A;  1MEM A;  5J94 A;  3QJ3 A;  1YK7 A;  3H89 A;  2PBH A;  3IV2 A;  3OF8 A;  1PCI A;  1BGO A;  3V6C A;  1EWP A;  4AXL A;  3H8C A;  3IMA A;  3H7D A;  1O0E A;  3U8E A;  2AUZ A;  2AUX A;  1THE A;  2R9N A;  2NQI A;  2AU1 A;  2F1G A;  1ZCM A;  2FUD A;  1PXV A;  2R9M A;  4YYU A;  1MS6 A;  4YYS A;  4Q8G A;  1PBH A;  2CB5 A;  3P5V A;  1QMY A;  1ZIV A;  2F7D A;  4DMY A;  2XU3 A;  1NQC A;  3BOW A;  3HWN A;  2DCB A;  3ZUA A;  2FRQ A;  1CJL A;  1SNK A;  2IPP B;  1U5I A;  3NHE A;  5A24 A;  5CVM A;  3PBH A;  3O1G A;  1CVZ A;  2DCD A;  1PPD A;  3KKU A;  8PCH A;  3K24 A;  1F29 A;  1U9Q X;  2OP3 A;  2FT2 A;  4K7C A;  3PDF A;  3K8U A;  1BY8 A;  1EF7 A;  1MHW A;  4FK5 A;  2AYN A;  1EWL A;  3BPF A;  4AXM A;  1AEC A;  2NQD B;  2ACT A;  1CTE A;  2GHU A;  2R9C A;  2Y6E A;  2IBI A;  4CZW A;  1F2B A;  3V6E A;  1GEC E;  4N8W A;  1MDW A;  3QT4 A;  4PP1 A;  1Y4H A;  4BQV A;  1KHQ A;  1KFX L;  3KWB X;  1VSN A;  5CVO B;  3GCB A;  4W5C A;  2FYE A;  3I3T A;  1AIM A;  4CDD B;  4QBB A;  1S4V A;  2XU1 A;  2FO5 A;  4XR7 A;  3OF9 A;  4ZUX U;  1AU0 A;  1GLO A;  4G54 A;  3USV A;  2DCC A;  3AI8 A;  2GFO A;  3HHI A;  2P7U A;  1ME4 A;  3PNR A;  5F02 A;  1MIR A;  3WXE A;  5K16 A;  3C9E A;  2JQG R;  4MZO A;  2R9O A;  2FTD A;  2HH5 A;  3OIS A;  4QH6 A;  2R6N A;  2ATO A;  4X6J A;  4YYR A;  9PAP A;  3LFY A;  2E03 A;  3M99 A;  3WXF A;  4P6E A;  4MSX A;  1SP4 B;  4BS5 A;  3S3R A;  2OZ2 A;  1HUC B;  3MHH A;  2AS8 A;  2DJF B;  4Q8H A;  1Y08 A;  4YYQ A;  3IOQ A;  2FQ9 A;  1Q6K A;  5CVN B;  1MEG A;  1PPP A;  2DC6 A;  2PAD A;  3DF0 A;  4BSQ A;  1CQD A;  2XU4 A;  2YJ8 A;  3TNX A;  6PAD A;  1DF0 A;  1ITO A;  4FJC A;  4N79 A;  4RY2 A;  1XKG A;  1EWM A;  5JH3 A;  3BC3 A;  4BS6 A;  4P6G A;  4CDC B;  3KW9 A;  1U9X A;  3HD3 A;  1KHP A;  2HHN A;  5PAD A;  2G8E A;  3KX1 A;  5CHV A;  3PW3 A;  3IEJ A;  2G7Y A;  3K9M A;  2ARY A;  3H8B A;  1NPZ A;  4I04 A;  3KSE A;  2YJ9 A;  3H6S A;  3WXG A;  4CDE B;  4PAD A;  1BP4 A;  3IUT A;  3I06 A;  1YT7 A;  1DEU A;  1KFU L;  4PI3 A;  1STF E;  4CDF B;  2DJG B;  1AYW A;  4YV8 A;  4QRX A;  1FH0 A;  2VHF A;  1TU6 A;  2OUL A;  4FIP A;  1PIP A;  1YAL A;  1PAD A;  2B1M A;  3RVX A;  1NB3 A;  4X6H A;  2P86 A;  2YJC A;  2NQA A;  3CBJ A;  3BCN A;  3P5X A;  1PPN A;  2O6X A;  2FRA A;  1BQI A;  2YJB A;  1CSB B;  2AIM A;  3BWK A;  2DZY A;  1AU2 A;  1NLJ A;  4PP2 E;  2C0Y A;  2BDZ A;  3S3Q A;  4YYW A;  3CH3 X;  1ME3 A;  2DC7 A;  3P5U A;  1AYV A;  5CHT A;  3RVV A;  2G6D A;  4DMX A;  1A6R A;  1NB5 A;  2H7J A;  2B1N A;  3QSD A;  4QRG A;  3HHA A;  2Y5B A;  1GCB A;  1PE6 A;  1KXR A;  1QDQ A;  4MZS A;  2HXZ A;  2VHS A;  4KLB A;  2AVW A;  4HWY A;  3KFQ A;  1CPJ A;  1AYU A;  4YYV A;  3RVW A;  1K3B B;  2HD5 A;  3D6S A;  1QOL A;  1YVB A;  3N3K A;  1ATK A;  1GMY A;  3MOR A;  1PPO A;  2DC8 A;  2XU5 A;  3CBK A; 
#chains in the Genus database with same CATH topology
 3PT2 A;  1F2C A;  2PNS A;  1QXP A;  4PT5 A;  2WBF X;  3OVZ A;  4WA6 A;  2NQG A;  4XUI A;  2JQF R;  4W4U A;  2PRE A;  3KWZ A;  3LXS A;  5JA7 A;  2YJ2 A;  3E1Z B;  1EWO A;  3MTN A;  1CV8 A;  3N4C A;  3BPM A;  4OVZ B;  1POP A;  4BOP A;  1X9Y A;  2E02 A;  4QRV A;  4YVA A;  2P0R A;  4N4Z A;  2R9F A;  5EF4 A;  2BTW B;  1NL6 A;  3CH2 X;  3N3G A;  1AU4 A;  7PCK A;  5EGW A;  3F5V A;  1IWD A;  1TL9 A;  4W5B A;  1U9W A;  2DC9 A;  3P5W A;  1AU3 A;  3ERV A;  2BDL A;  2E00 A;  1CB5 A;  2CIO A;  4BPV A;  1ICF A;  1VJV A;  4RF1 A;  3IHP A;  3B79 A;  1TLO A;  2DCA A;  3MHS A;  3OVX A;  1F2A A;  2AYO A;  4P16 A;  2HWK A;  1U9V A;  2G8J A;  1YK8 A;  4A5U A;  3O0U A;  2E01 A;  1CS8 A;  1M6D A;  1JQP A;  3F75 A;  4I07 A;  4X6I A;  4OEL A;  2DZZ A;  4OEM A;  4I05 A;  5FPW A;  1MEM A;  5J94 A;  3MJ5 A;  4BOZ A;  3QJ3 A;  1YK7 A;  3H89 A;  1UKF A;  2PBH A;  3IV2 A;  3OF8 A;  1PCI A;  1BGO A;  3V6C A;  1EWP A;  2Z84 A;  4AXL A;  3H8C A;  3IMA A;  3H7D A;  1O0E A;  3U8E A;  2AUZ A;  2AUX A;  1THE A;  2R9N A;  3OQC A;  2NQI A;  3BB7 A;  2AU1 A;  2F1G A;  1ZCM A;  2FUD A;  1PXV A;  2R9M A;  4YYU A;  1MS6 A;  4YYS A;  4Q8G A;  1PBH A;  2DOS A;  2CB5 A;  3P5V A;  5E6J A;  1QMY A;  4ZTB A;  1ZIV A;  2F7D A;  1YZB A;  4DMY A;  2XU3 A;  3PSE A;  1NQC A;  3BOW A;  3HWN A;  2DCB A;  3ZUA A;  2FRQ A;  1CJL A;  3PHX A;  1SNK A;  2IPP B;  3BBA A;  1U5I A;  3NHE A;  5A24 A;  5CVM A;  3PBH A;  2UZJ A;  3O1G A;  4IP3 A;  1CVZ A;  2DCD A;  1PPD A;  3KKU A;  8PCH A;  3K24 A;  4R3D A;  1F29 A;  1PVJ A;  3MP2 A;  1U9Q X;  2OP3 A;  4OW0 A;  2FT2 A;  4K7C A;  3TRK A;  3PDF A;  3K8U A;  1BY8 A;  1EF7 A;  1MHW A;  4FK5 A;  2AYN A;  1EWL A;  3B21 A;  3BPF A;  3IFU A;  4AXM A;  1AEC A;  2NQD B;  2ACT A;  1CTE A;  2GHU A;  2R9C A;  2Y6E A;  2IBI A;  4CZW A;  3ZNH A;  1F2B A;  3V6E A;  1GEC E;  3RNV A;  2FE8 A;  4N8W A;  1MDW A;  4REZ A;  3QT4 A;  4PP1 A;  1Y4H A;  4BQV A;  1KHQ A;  3W30 A;  1KFX L;  3KWB X;  1VSN A;  4RNA A;  4HXD B;  5CVO B;  3GCB A;  4W5C A;  2FYE A;  3I3T A;  1AIM A;  4CDD B;  2BU3 A;  4QBB A;  1S4V A;  2XU1 A;  2FO5 A;  4RKX A;  4XR7 A;  3OF9 A;  4ZUX U;  1AU0 A;  5EZQ A;  1DKI A;  5EZS A;  4BOU A;  3PRM A;  1GLO A;  4D8E A;  4G54 A;  3USV A;  2DCC A;  3AI8 A;  2GFO A;  3HHI A;  2P7U A;  1ME4 A;  3PNR A;  5F02 A;  1MIR A;  3PRP A;  3WXE A;  5K16 A;  3C9E A;  5JZE A;  2JQG R;  3C0R A;  4MZO A;  2R9O A;  2FTD A;  2HH5 A;  3OIS A;  4QH6 A;  2R6N A;  4BOS A;  2ATO A;  2JRI A;  4X6J A;  4YYR A;  9PAP A;  3LFY A;  2E03 A;  3M99 A;  3WXF A;  4P6E A;  4MSX A;  1SP4 B;  4BS5 A;  4BOQ A;  4IUM A;  3S3R A;  2OZ2 A;  1HUC B;  3MHH A;  4M0W A;  2AS8 A;  2DJF B;  4Q8H A;  1Y08 A;  4YYQ A;  3IOQ A;  2FQ9 A;  1Q6K A;  5CVN B;  1MEG A;  1PPP A;  2DC6 A;  2PAD A;  2J7Q A;  3DF0 A;  4RF0 A;  3TMP A;  3W31 A;  4BSQ A;  3MTV A;  1CQD A;  2XU4 A;  2YJ8 A;  3TNX A;  6PAD A;  1DF0 A;  1ITO A;  4FJC A;  4N79 A;  4RY2 A;  1XKG A;  1EWM A;  5JH3 A;  3BC3 A;  4BS6 A;  4MM3 B;  4P6G A;  4CDC B;  3KW9 A;  1U9X A;  3E9S A;  3HD3 A;  1KHP A;  2HHN A;  5PAD A;  2G8E A;  3KX1 A;  5CHV A;  2AGA A;  3IEJ A;  2G7Y A;  3PW3 A;  3K9M A;  2ARY A;  3H8B A;  1NPZ A;  4I04 A;  4GUA A;  3KSE A;  2YJ9 A;  3H6S A;  3WXG A;  4CDE B;  4PAD A;  1BP4 A;  3IUT A;  3I06 A;  1YT7 A;  1DEU A;  1KFU L;  4PI3 A;  1STF E;  3BY4 A;  4CDF B;  4D8I A;  2DJG B;  1AYW A;  3PHU A;  4YV8 A;  4QRX A;  1FH0 A;  2VHF A;  2JTC A;  1TU6 A;  2OUL A;  4FIP A;  1PIP A;  1YAL A;  1PAD A;  2B1M A;  3RVX A;  4D8B A;  1NB3 A;  4X6H A;  2P86 A;  2YJC A;  2NQA A;  3CBJ A;  3BCN A;  3P5X A;  1PPN A;  2O6X A;  2FRA A;  1BQI A;  2YJB A;  1CSB B;  5KO3 A;  2AIM A;  3BWK A;  2DZY A;  1AU2 A;  1NLJ A;  4PP2 E;  2C0Y A;  4XZX A;  2BDZ A;  3S3Q A;  4YYW A;  3CH3 X;  1ME3 A;  4MI7 A;  4OVZ A;  2DC7 A;  3P5U A;  1AYV A;  3O65 A;  5CHT A;  3RVV A;  2G6D A;  4DMX A;  1A6R A;  1NB5 A;  2H7J A;  2B1N A;  3QSD A;  4QRG A;  3HHA A;  2BTW A;  2Y5B A;  1GCB A;  1PE6 A;  1KXR A;  1QDQ A;  4MZS A;  2HXZ A;  2VHS A;  4KLB A;  3PHW A;  2AVW A;  4HWY A;  3KFQ A;  1CPJ A;  1AYU A;  4WUR A;  4YYV A;  2J7Q C;  3RVW A;  1K3B B;  2HD5 A;  3D6S A;  1QOL A;  1YVB A;  3N3K A;  1ATK A;  1GMY A;  3MOR A;  1PPO A;  2DC8 A;  2XU5 A;  3CBK A; 
#chains in the Genus database with same CATH homology
 1F2C A;  2PNS A;  1QXP A;  2WBF X;  3OVZ A;  4WA6 A;  2NQG A;  4XUI A;  2JQF R;  4W4U A;  2PRE A;  3KWZ A;  3LXS A;  5JA7 A;  2YJ2 A;  3E1Z B;  1EWO A;  3MTN A;  1CV8 A;  3N4C A;  3BPM A;  1POP A;  1X9Y A;  2E02 A;  4QRV A;  4YVA A;  2P0R A;  4N4Z A;  2R9F A;  5EF4 A;  1NL6 A;  3CH2 X;  3N3G A;  1AU4 A;  7PCK A;  4GUZ A;  5EGW A;  3F5V A;  1IWD A;  1TL9 A;  2VFB A;  4W5B A;  1U9W A;  2DC9 A;  3P5W A;  1AU3 A;  3ERV A;  2BDL A;  2E00 A;  1CB5 A;  2CIO A;  4BPV A;  1ICF A;  1VJV A;  3IHP A;  3B79 A;  1TLO A;  2DCA A;  3MHS A;  3OVX A;  1F2A A;  2AYO A;  1U9V A;  2G8J A;  1YK8 A;  1W4T A;  3O0U A;  2E01 A;  1CS8 A;  1M6D A;  1JQP A;  3F75 A;  4I07 A;  4X6I A;  4OEL A;  2DZZ A;  4OEM A;  4I05 A;  5FPW A;  1MEM A;  5J94 A;  4BGF A;  3QJ3 A;  1YK7 A;  3H89 A;  2PBH A;  3IV2 A;  3OF8 A;  1PCI A;  1BGO A;  3V6C A;  1EWP A;  4AXL A;  3H8C A;  3IMA A;  3H7D A;  1O0E A;  3U8E A;  2AUZ A;  2AUX A;  1THE A;  2R9N A;  2NQI A;  2AU1 A;  2F1G A;  1ZCM A;  2FUD A;  1PXV A;  2R9M A;  4YYU A;  1MS6 A;  4YYS A;  2VFC A;  4Q8G A;  1PBH A;  2CB5 A;  3P5V A;  1QMY A;  1ZIV A;  2F7D A;  4DMY A;  2XU3 A;  1NQC A;  3BOW A;  3HWN A;  2DCB A;  3ZUA A;  2FRQ A;  1CJL A;  1SNK A;  2IPP B;  1U5I A;  3NHE A;  5A24 A;  5CVM A;  3PBH A;  3O1G A;  1CVZ A;  2DCD A;  1PPD A;  3KKU A;  8PCH A;  3K24 A;  1F29 A;  1U9Q X;  2OP3 A;  2FT2 A;  4K7C A;  3PDF A;  3K8U A;  4NV7 A;  1BY8 A;  1EF7 A;  1MHW A;  4FK5 A;  2AYN A;  1EWL A;  3BPF A;  4AXM A;  1AEC A;  2NQD B;  2ACT A;  1CTE A;  2GHU A;  2R9C A;  2Y6E A;  2IBI A;  4CZW A;  1F2B A;  3V6E A;  1GEC E;  4N8W A;  1MDW A;  3QT4 A;  4PP1 A;  1Y4H A;  4BQV A;  1KHQ A;  1KFX L;  3KWB X;  1VSN A;  5CVO B;  3GCB A;  4NV8 A;  4W5C A;  2BSZ A;  2FYE A;  3I3T A;  1AIM A;  4CDD B;  4QBB A;  1S4V A;  2XU1 A;  2FO5 A;  4XR7 A;  3OF9 A;  4ZUX U;  1AU0 A;  1GLO A;  4G54 A;  3USV A;  2DCC A;  3AI8 A;  2GFO A;  3HHI A;  2P7U A;  1ME4 A;  3PNR A;  5F02 A;  1MIR A;  3WXE A;  5K16 A;  3C9E A;  2JQG R;  4MZO A;  2R9O A;  2FTD A;  2HH5 A;  3OIS A;  4QH6 A;  2R6N A;  2ATO A;  4X6J A;  4YYR A;  9PAP A;  3LFY A;  2E03 A;  3M99 A;  3WXF A;  3D9W A;  4P6E A;  4MSX A;  1SP4 B;  4BS5 A;  3S3R A;  2OZ2 A;  1HUC B;  3MHH A;  2AS8 A;  2DJF B;  4Q8H A;  1Y08 A;  4YYQ A;  3IOQ A;  2FQ9 A;  1GX3 A;  1Q6K A;  5CVN B;  1MEG A;  1PPP A;  2DC6 A;  2PAD A;  3DF0 A;  4BSQ A;  1CQD A;  2XU4 A;  2YJ8 A;  3TNX A;  6PAD A;  1DF0 A;  1ITO A;  4FJC A;  4N79 A;  4RY2 A;  1XKG A;  1EWM A;  5JH3 A;  3BC3 A;  4BS6 A;  4P6G A;  4CDC B;  3KW9 A;  1U9X A;  3HD3 A;  1KHP A;  2HHN A;  5PAD A;  2G8E A;  3KX1 A;  5CHV A;  3PW3 A;  3IEJ A;  2G7Y A;  4B55 A;  3K9M A;  1W5R A;  2ARY A;  3H8B A;  1NPZ A;  4I04 A;  3KSE A;  2YJ9 A;  1E2T A;  3H6S A;  3WXG A;  4CDE B;  4PAD A;  1BP4 A;  3IUT A;  3I06 A;  1YT7 A;  1DEU A;  1KFU L;  4PI3 A;  1STF E;  4CDF B;  2DJG B;  1AYW A;  4YV8 A;  4QRX A;  1FH0 A;  2VHF A;  1TU6 A;  2OUL A;  4FIP A;  1PIP A;  1YAL A;  1PAD A;  2B1M A;  3RVX A;  1NB3 A;  4X6H A;  2P86 A;  2YJC A;  2NQA A;  3CBJ A;  3BCN A;  3P5X A;  1PPN A;  2O6X A;  2FRA A;  1BQI A;  2YJB A;  1CSB B;  2AIM A;  3BWK A;  2DZY A;  1AU2 A;  1NLJ A;  4PP2 E;  2C0Y A;  2BDZ A;  1W6F A;  3LTW A;  3S3Q A;  4YYW A;  3CH3 X;  1ME3 A;  2DC7 A;  3P5U A;  1AYV A;  5CHT A;  3RVV A;  2G6D A;  4DMX A;  1A6R A;  1NB5 A;  2H7J A;  2B1N A;  3QSD A;  4QRG A;  3HHA A;  2Y5B A;  1GCB A;  1PE6 A;  1KXR A;  1QDQ A;  4MZS A;  2HXZ A;  2VHS A;  4C5P A;  4KLB A;  2AVW A;  4HWY A;  3KFQ A;  1CPJ A;  1AYU A;  4YYV A;  3RVW A;  1K3B B;  2HD5 A;  3D6S A;  1QOL A;  1YVB A;  3N3K A;  1ATK A;  1GMY A;  3MOR A;  1PPO A;  2DC8 A;  2XU5 A;  3CBK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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