3IUTA

The crystal structure of cruzain in complex with a tetrafluorophenoxymethyl ketone inhibitor
Total Genus 68
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
215
structure length
215
Chain Sequence
APAAVDWRARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLAGHPLTNLAEQMLVSCDKTDSGCSGGLMNNAFEWIVQENNGAVYTEDSYPYASGEGISPPCTTSGHTVGATITGHVELPQDEAQIAAWLAVNGPVAVAVDASSWMTYTGGVMTSCVSEQLDHGVLLVGYNDGAAVPYWIIKNSWTTQWGEEGYIRIAKGSNQCLVKEEASSAVVG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Nonpeptidic tetrafluorophenoxymethyl ketone cruzain inhibitors as promising new leads for chagas disease chemotherapy.
pubmed doi rcsb
molecule tags Hydrolase
source organism Trypanosoma cruzi
molecule keywords Cruzipain
total genus 68
structure length 215
sequence length 215
ec nomenclature ec 3.4.22.51: Cruzipain.
pdb deposition date 2009-08-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3iutA00
1MS6A 3H6SA 1PPDA 2CB5A 1QDQA 4QBBA 2R9MA 1EWPA 1PCIA 1EWOA 5J94A 3F75A 1KHQA 1CPJA 1MIRA 3O0UA 1F2AA 3IV2A 3I06A 4YYSA 4W5BA 2FRAA 2VHFA 8PCHA 4KLBA 2B1NA 1DF0A 4YVAA 2O6XA 2ARYA 1K3BB 1KFUL 2CIOA 3HHIA 3PW3A 1ITOA 2GHUA 3HWNA 3QSDA 2OP3A 1KXRA 3KSEA 1MEMA 1A6RA 1PBHA 2DZZA 3IOQA 4OELA 2FUDA 1BQIA 2NQGA 3WXFA 3LXSA 1Y08A 5PADA 2AS8A 3QJ3A 2AYNA 2IPPB 5CVNB 3V6CA 4W5CA 1CSBB 1YVBA 2YJBA 1PXVA 4QRVA 4HWYA 1BGOA 2AIMA 2DC8A 2HXZA 2F7DA 2YJ2A 4FIPA 1NB5A 4RY2A 3KX1A 3USVA 1O0EA 3P5UA 1F29A 1X9YA 4MSXA 2XU1A 2NQDB 1PPPA 1KHPA 1TU6A 1NQCA 1IWDA 2G7YA 2R9CA 2XU4A 1POPA 4W4UA 1ZIVA 2HD5A 2DC7A 4MZSA 1JQPA 1EWMA 1XKGA 1NB3A 2E00A 5CHVA 1GMYA 4YYUA 3GCBA 3PDFA 4MZOA 1EF7A 3H7DA 1Y4HA 3OF9A 5EGWA 2E03A 4YYQA 3IMAA 1QXPA 2XU3A 3O1GA 2R6NA 2PREA 3D6SA 1F2BA 1AU0A 3BWKA 3OVXA 4I05A 1YALA 1SP4B 3KWZA 2JQFR 4CDCB 1TLOA 4P6GA 3BPFA 1YK8A 1CVZA 4CZWA 1F2CA 2H7JA 3WXGA 1AU2A 2DJGB 2F1GA 3V6EA 3K9MA 2DCCA 3P5XA 5CHTA 2NQAA 4CDDB 1ME3A 5EF4A 4QRXA 4FK5A 3U8EA 3K8UA 1QMYA 4DMXA 1DEUA 4I04A 1CS8A 2R9OA 2NQIA 1VSNA 2HH5A 5CVMA 1U9WA 1THEA 4WA6A 1PPOA 4BSQA 1TL9A 4X6IA 2ACTA 2HHNA 5JA7A 3NHEA 1YK7A 3BC3A 1EWLA 1NPZA 2PADA 1CV8A 2P7UA 1KFXL 1AIMA 2AYOA 3ERVA 4YV8A 3QT4A 4X6HA 1PIPA 4YYRA 2DC6A 4K7CA 3CBKA 3IUTA 4P6EA 4BPVA 4YYVA 5A24A 3OF8A 1GCBA 3P5VA 2DCDA 3IEJA 2C0YA 4Q8GA 2OZ2A 1FH0A 2FRQA 2GFOA 3KFQA 2Y6EA 3MHSA 1BP4A 1PPNA 2AVWA 3N3GA 4N4ZA 2PNSA 2FQ9A 4PADA 1VJVA 5FPWA 2G8JA 3S3RA 4PP1A 3F5VA 3WXEA 2FTDA 1YT7A 3LFYA 3CH2X 1QOLA 4AXMA 1CB5A 2PBHA 3CBJA 3PBHA 1U5IA 2R9NA 3KW9A 2DC9A 4PP2E 3DF0A 4N8WA 5CVOB 1AECA 1NL6A 2JQGR 3KWBX 2YJCA 2G6DA 1U9VA 4OEMA 9PAPA 1HUCB 1CTEA 3P5WA 1AU4A 4BS6A 3C9EA 2P86A 2Y5BA 2AU1A 4CDEB 4XR7A 2DJFB 4CDFB 1AYUA 3RVXA 1AU3A 2IBIA 3S3QA 3MHHA 3N3KA 2E02A 3HHAA 4PI3A 1CQDA 1MEGA 2BDLA 3B79A 1Q6KA 1MHWA 3E1ZB 1PADA 1CJLA 4QH6A 1ICFA 4BS5A 3RVWA 3BCNA 3IHPA 3AI8A 4N79A 3PNRA 1U9QX 3OISA 3RVVA 1U9XA 1MDWA 3TNXA 4I07A 2B1MA 4Q8HA 3OVZA 1SNKA 2DCAA 2P0RA 2DZYA 3H8CA 2ATOA 4BQVA 2YJ9A 4AXLA 4DMYA 3H8BA 1ATKA 3CH3X 1S4VA 2WBFX 3HD3A 4G54A 3I3TA 1BY8A 2XU5A 1GLOA 2E01A 1GECE 2BDZA 4XUIA 2G8EA 1AYWA 3N4CA 6PADA 4QRGA 2FYEA 2R9FA 4YYWA 4ZUXU 1M6DA 3K24A 2DCBA 3BOWA 1NLJA 3KKUA 2FO5A 3MTNA 3ZUAA 2AUZA 3M99A 2FT2A 1ZCMA 5K16A 5JH3A 4X6JA 2AUXA 2VHSA 1STFE 5F02A 3BPMA 2OULA 1PE6A 1AYVA 2YJ8A 4FJCA 3H89A 7PCKA 3MORA 1ME4A
chains in the Genus database with same CATH superfamily
1MS6A 3H6SA 4D8EA 1PPDA 2CB5A 1QDQA 4QBBA 2R9MA 1EWPA 1PCIA 1EWOA 5J94A 3F75A 1KHQA 5JZEA 1CPJA 1MIRA 3O0UA 1F2AA 3IV2A 3I06A 4YYSA 4W5BA 2FRAA 2VHFA 8PCHA 4KLBA 2B1NA 1DF0A 4YVAA 2O6XA 2ARYA 1K3BB 3MTVA 1KFUL 2CIOA 3HHIA 3PW3A 1ITOA 2GHUA 4REZA 3HWNA 3QSDA 2OP3A 1KXRA 3KSEA 1MEMA 1A6RA 1PBHA 2DZZA 3IOQA 4OELA 4IUMA 2FUDA 1BQIA 2NQGA 3WXFA 3LXSA 1Y08A 5PADA 2AS8A 3QJ3A 2AYNA 2IPPB 5CVNB 3V6CA 4W5CA 1CSBB 1YVBA 2YJBA 5KO3A 1PXVA 4QRVA 5E6JA 4RF1A 4HWYA 1BGOA 2AIMA 2DC8A 2HXZA 2F7DA 2YJ2A 4FIPA 1NB5A 4RY2A 3KX1A 3MP2A 4PT5A 4R3DA 3USVA 1O0EA 3P5UA 1F29A 1X9YA 4MSXA 2XU1A 4OVZB 2NQDB 1PPPA 1KHPA 1TU6A 1NQCA 3PRMA 1IWDA 2G7YA 2R9CA 2XU4A 1POPA 4W4UA 1ZIVA 2HD5A 2DC7A 4MZSA 1JQPA 1EWMA 1XKGA 1NB3A 3PHUA 2E00A 4M0WA 3BY4A 5CHVA 1GMYA 4BOSA 4YYUA 2UZJA 3GCBA 3PDFA 4MZOA 1EF7A 3H7DA 1Y4HA 3OF9A 5EGWA 2E03A 4RNAA 4YYQA 3IMAA 1QXPA 2XU3A 3O1GA 3ZNHA 2R6NA 2PREA 3D6SA 1F2BA 1AU0A 1PVJA 3BWKA 3OVXA 2BTWB 4I05A 1YALA 1SP4B 4WURA 3KWZA 3RNVA 2JQFR 1YZBA 4CDCB 1TLOA 4P6GA 3BPFA 3W30A 1YK8A 1CVZA 4CZWA 1F2CA 2H7JA 3B21A 3WXGA 1AU2A 2DJGB 2F1GA 3V6EA 3K9MA 4MI7A 2DCCA 3P5XA 5CHTA 1DKIA 2NQAA 4CDDB 3BB7A 1ME3A 5EF4A 4QRXA 4FK5A 3U8EA 3K8UA 2JRIA 1QMYA 4DMXA 1DEUA 3PT2A 4I04A 1CS8A 2R9OA 2NQIA 4BOQA 1VSNA 2HH5A 5CVMA 1U9WA 1THEA 4WA6A 1PPOA 4BSQA 1TL9A 4X6IA 2AGAA 2ACTA 2HHNA 4BOPA 5JA7A 3NHEA 1YK7A 3BC3A 1EWLA 1NPZA 2PADA 2BU3A 3TMPA 1CV8A 2P7UA 5EZSA 1KFXL 1AIMA 2AYOA 3ERVA 4XZXA 4YV8A 3QT4A 4X6HA 1PIPA 4YYRA 2DC6A 4HXDB 4K7CA 3CBKA 3IUTA 4P6EA 4BPVA 4YYVA 5A24A 3OF8A 1GCBA 4OW0A 4RKXA 3P5VA 2DCDA 3IEJA 2C0YA 4Q8GA 2OZ2A 1FH0A 2FRQA 2GFOA 3KFQA 2Y6EA 3MHSA 1BP4A 1PPNA 3BBAA 3IFUA 2AVWA 3N3GA 4N4ZA 2PNSA 2FQ9A 4PADA 1VJVA 3PSEA 4OVZA 2G8JA 5FPWA 3S3RA 4PP1A 3F5VA 4MM3B 3WXEA 4GUAA 2FTDA 1YT7A 3LFYA 3CH2X 1QOLA 4AXMA 1CB5A 1UKFA 2PBHA 3CBJA 3PBHA 1U5IA 3PHXA 2R9NA 3KW9A 5EZQA 2DC9A 4PP2E 3DF0A 4N8WA 5CVOB 3C0RA 1AECA 1NL6A 2JQGR 3KWBX 2YJCA 2G6DA 3TRKA 1U9VA 4OEMA 9PAPA 1HUCB 1CTEA 3P5WA 1AU4A 4BS6A 3C9EA 2P86A 2Y5BA 2AU1A 4D8IA 4CDEB 4XR7A 2DJFB 4CDFB 1AYUA 4ZTBA 3RVXA 2BTWA 3PRPA 1AU3A 4D8BA 2FE8A 2IBIA 3S3QA 3MHHA 3N3KA 2E02A 3E9SA 3HHAA 4PI3A 1CQDA 1MEGA 3MJ5A 2BDLA 3B79A 1Q6KA 1MHWA 4RF0A 3E1ZB 2DOSA 1PADA 1CJLA 4QH6A 1ICFA 4BS5A 3RVWA 3BCNA 3IHPA 3AI8A 4N79A 3PNRA 1U9QX 3OISA 3RVVA 1U9XA 1MDWA 3TNXA 4I07A 2Z84A 2J7QA 2B1MA 4P16A 4Q8HA 3OVZA 1SNKA 2DCAA 2P0RA 2DZYA 3H8CA 2JTCA 2ATOA 4BQVA 2YJ9A 4AXLA 4DMYA 3H8BA 4BOZA 1ATKA 3CH3X 1S4VA 2WBFX 3HD3A 4G54A 3I3TA 4BOUA 3PHWA 1BY8A 2XU5A 3OQCA 1GLOA 2E01A 1GECE 2BDZA 4XUIA 2G8EA 1AYWA 3W31A 4IP3A 3N4CA 6PADA 4QRGA 2FYEA 2R9FA 4YYWA 4ZUXU 1M6DA 3K24A 2DCBA 3BOWA 4A5UA 1NLJA 2J7QC 3KKUA 2FO5A 3MTNA 3ZUAA 2AUZA 3M99A 2FT2A 1ZCMA 5K16A 5JH3A 4X6JA 2AUXA 2HWKA 3O65A 2VHSA 1STFE 5F02A 3BPMA 2OULA 1PE6A 1AYVA 2YJ8A 4FJCA 3H89A 7PCKA 3MORA 1ME4A
chains in the Genus database with same CATH topology
1MS6A 3H6SA 1PPDA 2CB5A 1QDQA 4QBBA 2R9MA 1EWPA 1PCIA 1EWOA 5J94A 3F75A 1KHQA 1CPJA 1MIRA 3O0UA 1F2AA 3IV2A 3I06A 4YYSA 4W5BA 2FRAA 2VHFA 4NV8A 8PCHA 4KLBA 2B1NA 1DF0A 4YVAA 2O6XA 2ARYA 1K3BB 1KFUL 2CIOA 3HHIA 2BSZA 3PW3A 1ITOA 2GHUA 3HWNA 4B55A 3QSDA 2OP3A 1KXRA 3KSEA 1MEMA 1A6RA 1PBHA 2DZZA 3IOQA 4OELA 2FUDA 1BQIA 2NQGA 3WXFA 3LXSA 1Y08A 5PADA 1W6FA 1E2TA 2AS8A 3QJ3A 2AYNA 2IPPB 5CVNB 3V6CA 4W5CA 1CSBB 1YVBA 2YJBA 1PXVA 4QRVA 4HWYA 1BGOA 2AIMA 2DC8A 2HXZA 2F7DA 2YJ2A 4FIPA 1NB5A 4RY2A 3KX1A 3USVA 1O0EA 3P5UA 1F29A 1X9YA 4MSXA 2XU1A 2NQDB 1PPPA 1KHPA 1TU6A 1NQCA 1IWDA 2G7YA 2R9CA 2XU4A 1POPA 4W4UA 1ZIVA 2HD5A 2DC7A 4MZSA 1JQPA 1EWMA 1XKGA 1NB3A 2E00A 5CHVA 1GMYA 4YYUA 3GCBA 3PDFA 1W5RA 4MZOA 1EF7A 3H7DA 1Y4HA 3OF9A 5EGWA 2E03A 4YYQA 3IMAA 1QXPA 2XU3A 3O1GA 2R6NA 2PREA 3D6SA 1F2BA 1AU0A 3BWKA 3OVXA 4I05A 1YALA 1SP4B 3KWZA 2JQFR 4CDCB 1TLOA 4P6GA 3BPFA 1YK8A 1CVZA 4CZWA 1F2CA 2H7JA 2VFCA 3WXGA 1AU2A 2DJGB 2F1GA 3V6EA 3K9MA 2DCCA 3P5XA 5CHTA 2NQAA 4CDDB 1ME3A 5EF4A 4QRXA 4FK5A 3U8EA 3K8UA 1QMYA 4DMXA 1DEUA 4I04A 1CS8A 2R9OA 2NQIA 1VSNA 2HH5A 5CVMA 1U9WA 1THEA 4WA6A 1PPOA 4BSQA 1TL9A 4X6IA 2ACTA 2HHNA 5JA7A 3NHEA 1YK7A 3BC3A 1EWLA 1NPZA 2PADA 1CV8A 2P7UA 1KFXL 1AIMA 2AYOA 3ERVA 4YV8A 3QT4A 4X6HA 1PIPA 4YYRA 2DC6A 1GX3A 2VFBA 4K7CA 3CBKA 3IUTA 4P6EA 4BPVA 4YYVA 5A24A 3OF8A 1GCBA 3P5VA 2DCDA 3IEJA 2C0YA 4Q8GA 2OZ2A 1FH0A 2FRQA 2GFOA 3KFQA 2Y6EA 3MHSA 1BP4A 1PPNA 2AVWA 3N3GA 4N4ZA 2PNSA 2FQ9A 4PADA 1VJVA 5FPWA 2G8JA 3S3RA 4PP1A 3F5VA 3WXEA 2FTDA 1W4TA 1YT7A 3LFYA 3CH2X 1QOLA 4AXMA 1CB5A 2PBHA 3CBJA 3PBHA 1U5IA 2R9NA 3KW9A 2DC9A 4PP2E 3DF0A 4N8WA 5CVOB 1AECA 1NL6A 2JQGR 3KWBX 2YJCA 2G6DA 1U9VA 4OEMA 9PAPA 1HUCB 1CTEA 3P5WA 1AU4A 4BS6A 3C9EA 2P86A 2Y5BA 2AU1A 4GUZA 4CDEB 4XR7A 2DJFB 4CDFB 1AYUA 3RVXA 1AU3A 2IBIA 3S3QA 3MHHA 3N3KA 2E02A 3HHAA 4PI3A 1CQDA 1MEGA 2BDLA 3B79A 1Q6KA 1MHWA 3E1ZB 1PADA 1CJLA 4QH6A 1ICFA 4BS5A 3RVWA 3BCNA 3IHPA 3AI8A 4N79A 3PNRA 1U9QX 3OISA 3RVVA 1U9XA 1MDWA 3TNXA 4I07A 2B1MA 4Q8HA 3OVZA 4NV7A 1SNKA 2DCAA 2P0RA 2DZYA 3H8CA 2ATOA 4BQVA 2YJ9A 4AXLA 4DMYA 3H8BA 3D9WA 1ATKA 3CH3X 3LTWA 1S4VA 2WBFX 3HD3A 4G54A 3I3TA 1BY8A 2XU5A 1GLOA 2E01A 1GECE 2BDZA 4XUIA 2G8EA 1AYWA 3N4CA 6PADA 4QRGA 2FYEA 2R9FA 4YYWA 4ZUXU 1M6DA 3K24A 2DCBA 3BOWA 1NLJA 3KKUA 2FO5A 3MTNA 3ZUAA 2AUZA 3M99A 2FT2A 1ZCMA 5K16A 5JH3A 4X6JA 2AUXA 4BGFA 2VHSA 1STFE 5F02A 3BPMA 2OULA 4C5PA 1PE6A 1AYVA 2YJ8A 4FJCA 3H89A 7PCKA 3MORA 1ME4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MS6 A;  3H6S A;  1PPD A;  2CB5 A;  1QDQ A;  4QBB A;  2R9M A;  1EWP A;  1PCI A;  1EWO A;  5J94 A;  3F75 A;  1KHQ A;  1CPJ A;  1MIR A;  3O0U A;  1F2A A;  3IV2 A;  3I06 A;  4YYS A;  4W5B A;  2FRA A;  2VHF A;  8PCH A;  4KLB A;  2B1N A;  1DF0 A;  4YVA A;  2O6X A;  2ARY A;  1K3B B;  1KFU L;  2CIO A;  3HHI A;  3PW3 A;  1ITO A;  2GHU A;  3HWN A;  3QSD A;  2OP3 A;  1KXR A;  3KSE A;  1MEM A;  1A6R A;  1PBH A;  2DZZ A;  3IOQ A;  4OEL A;  2FUD A;  1BQI A;  2NQG A;  3WXF A;  3LXS A;  1Y08 A;  5PAD A;  2AS8 A;  3QJ3 A;  2AYN A;  2IPP B;  5CVN B;  3V6C A;  4W5C A;  1CSB B;  1YVB A;  2YJB A;  1PXV A;  4QRV A;  4HWY A;  1BGO A;  2AIM A;  2DC8 A;  2HXZ A;  2F7D A;  2YJ2 A;  4FIP A;  1NB5 A;  4RY2 A;  3KX1 A;  3USV A;  1O0E A;  3P5U A;  1F29 A;  1X9Y A;  4MSX A;  2XU1 A;  2NQD B;  1PPP A;  1KHP A;  1TU6 A;  1NQC A;  1IWD A;  2G7Y A;  2R9C A;  2XU4 A;  1POP A;  4W4U A;  1ZIV A;  2HD5 A;  2DC7 A;  4MZS A;  1JQP A;  1EWM A;  1XKG A;  1NB3 A;  2E00 A;  5CHV A;  1GMY A;  4YYU A;  3GCB A;  3PDF A;  4MZO A;  1EF7 A;  3H7D A;  1Y4H A;  3OF9 A;  5EGW A;  2E03 A;  4YYQ A;  3IMA A;  1QXP A;  2XU3 A;  3O1G A;  2R6N A;  2PRE A;  3D6S A;  1F2B A;  1AU0 A;  3BWK A;  3OVX A;  4I05 A;  1YAL A;  1SP4 B;  3KWZ A;  2JQF R;  4CDC B;  1TLO A;  4P6G A;  3BPF A;  1YK8 A;  1CVZ A;  4CZW A;  1F2C A;  2H7J A;  3WXG A;  1AU2 A;  2DJG B;  2F1G A;  3V6E A;  3K9M A;  2DCC A;  3P5X A;  5CHT A;  2NQA A;  4CDD B;  1ME3 A;  5EF4 A;  4QRX A;  4FK5 A;  3U8E A;  3K8U A;  1QMY A;  4DMX A;  1DEU A;  4I04 A;  1CS8 A;  2R9O A;  2NQI A;  1VSN A;  2HH5 A;  5CVM A;  1U9W A;  1THE A;  4WA6 A;  1PPO A;  4BSQ A;  1TL9 A;  4X6I A;  2ACT A;  2HHN A;  5JA7 A;  3NHE A;  1YK7 A;  3BC3 A;  1EWL A;  1NPZ A;  2PAD A;  1CV8 A;  2P7U A;  1KFX L;  1AIM A;  2AYO A;  3ERV A;  4YV8 A;  3QT4 A;  4X6H A;  1PIP A;  4YYR A;  2DC6 A;  4K7C A;  3CBK A;  3IUT A;  4P6E A;  4BPV A;  4YYV A;  5A24 A;  3OF8 A;  1GCB A;  3P5V A;  2DCD A;  3IEJ A;  2C0Y A;  4Q8G A;  2OZ2 A;  1FH0 A;  2FRQ A;  2GFO A;  3KFQ A;  2Y6E A;  3MHS A;  1BP4 A;  1PPN A;  2AVW A;  3N3G A;  4N4Z A;  2PNS A;  2FQ9 A;  4PAD A;  1VJV A;  5FPW A;  2G8J A;  3S3R A;  4PP1 A;  3F5V A;  3WXE A;  2FTD A;  1YT7 A;  3LFY A;  3CH2 X;  1QOL A;  4AXM A;  1CB5 A;  2PBH A;  3CBJ A;  3PBH A;  1U5I A;  2R9N A;  3KW9 A;  2DC9 A;  4PP2 E;  3DF0 A;  4N8W A;  5CVO B;  1AEC A;  1NL6 A;  2JQG R;  3KWB X;  2YJC A;  2G6D A;  1U9V A;  4OEM A;  9PAP A;  1HUC B;  1CTE A;  3P5W A;  1AU4 A;  4BS6 A;  3C9E A;  2P86 A;  2Y5B A;  2AU1 A;  4CDE B;  4XR7 A;  2DJF B;  4CDF B;  1AYU A;  3RVX A;  1AU3 A;  2IBI A;  3S3Q A;  3MHH A;  3N3K A;  2E02 A;  3HHA A;  4PI3 A;  1CQD A;  1MEG A;  2BDL A;  3B79 A;  1Q6K A;  1MHW A;  3E1Z B;  1PAD A;  1CJL A;  4QH6 A;  1ICF A;  4BS5 A;  3RVW A;  3BCN A;  3IHP A;  3AI8 A;  4N79 A;  3PNR A;  1U9Q X;  3OIS A;  3RVV A;  1U9X A;  1MDW A;  3TNX A;  4I07 A;  2B1M A;  4Q8H A;  3OVZ A;  1SNK A;  2DCA A;  2P0R A;  2DZY A;  3H8C A;  2ATO A;  4BQV A;  2YJ9 A;  4AXL A;  4DMY A;  3H8B A;  1ATK A;  3CH3 X;  1S4V A;  2WBF X;  3HD3 A;  4G54 A;  3I3T A;  1BY8 A;  2XU5 A;  1GLO A;  2E01 A;  1GEC E;  2BDZ A;  4XUI A;  2G8E A;  1AYW A;  3N4C A;  6PAD A;  4QRG A;  2FYE A;  2R9F A;  4YYW A;  4ZUX U;  1M6D A;  3K24 A;  2DCB A;  3BOW A;  1NLJ A;  3KKU A;  2FO5 A;  3MTN A;  3ZUA A;  2AUZ A;  3M99 A;  2FT2 A;  1ZCM A;  5K16 A;  5JH3 A;  4X6J A;  2AUX A;  2VHS A;  1STF E;  5F02 A;  3BPM A;  2OUL A;  1PE6 A;  1AYV A;  2YJ8 A;  4FJC A;  3H89 A;  7PCK A;  3MOR A;  1ME4 A; 
#chains in the Genus database with same CATH topology
 1MS6 A;  3H6S A;  4D8E A;  1PPD A;  2CB5 A;  1QDQ A;  4QBB A;  2R9M A;  1EWP A;  1PCI A;  1EWO A;  5J94 A;  3F75 A;  1KHQ A;  5JZE A;  1CPJ A;  1MIR A;  3O0U A;  1F2A A;  3IV2 A;  3I06 A;  4YYS A;  4W5B A;  2FRA A;  2VHF A;  8PCH A;  4KLB A;  2B1N A;  1DF0 A;  4YVA A;  2O6X A;  2ARY A;  1K3B B;  3MTV A;  1KFU L;  2CIO A;  3HHI A;  3PW3 A;  1ITO A;  2GHU A;  4REZ A;  3HWN A;  3QSD A;  2OP3 A;  1KXR A;  3KSE A;  1MEM A;  1A6R A;  1PBH A;  2DZZ A;  3IOQ A;  4OEL A;  4IUM A;  2FUD A;  1BQI A;  2NQG A;  3WXF A;  3LXS A;  1Y08 A;  5PAD A;  2AS8 A;  3QJ3 A;  2AYN A;  2IPP B;  5CVN B;  3V6C A;  4W5C A;  1CSB B;  1YVB A;  2YJB A;  5KO3 A;  1PXV A;  4QRV A;  5E6J A;  4RF1 A;  4HWY A;  1BGO A;  2AIM A;  2DC8 A;  2HXZ A;  2F7D A;  2YJ2 A;  4FIP A;  1NB5 A;  4RY2 A;  3KX1 A;  3MP2 A;  4PT5 A;  4R3D A;  3USV A;  1O0E A;  3P5U A;  1F29 A;  1X9Y A;  4MSX A;  2XU1 A;  4OVZ B;  2NQD B;  1PPP A;  1KHP A;  1TU6 A;  1NQC A;  3PRM A;  1IWD A;  2G7Y A;  2R9C A;  2XU4 A;  1POP A;  4W4U A;  1ZIV A;  2HD5 A;  2DC7 A;  4MZS A;  1JQP A;  1EWM A;  1XKG A;  1NB3 A;  3PHU A;  2E00 A;  4M0W A;  3BY4 A;  5CHV A;  1GMY A;  4BOS A;  4YYU A;  2UZJ A;  3GCB A;  3PDF A;  4MZO A;  1EF7 A;  3H7D A;  1Y4H A;  3OF9 A;  5EGW A;  2E03 A;  4RNA A;  4YYQ A;  3IMA A;  1QXP A;  2XU3 A;  3O1G A;  3ZNH A;  2R6N A;  2PRE A;  3D6S A;  1F2B A;  1AU0 A;  1PVJ A;  3BWK A;  3OVX A;  2BTW B;  4I05 A;  1YAL A;  1SP4 B;  4WUR A;  3KWZ A;  3RNV A;  2JQF R;  1YZB A;  4CDC B;  1TLO A;  4P6G A;  3BPF A;  3W30 A;  1YK8 A;  1CVZ A;  4CZW A;  1F2C A;  2H7J A;  3B21 A;  3WXG A;  1AU2 A;  2DJG B;  2F1G A;  3V6E A;  3K9M A;  4MI7 A;  2DCC A;  3P5X A;  5CHT A;  1DKI A;  2NQA A;  4CDD B;  3BB7 A;  1ME3 A;  5EF4 A;  4QRX A;  4FK5 A;  3U8E A;  3K8U A;  2JRI A;  1QMY A;  4DMX A;  1DEU A;  3PT2 A;  4I04 A;  1CS8 A;  2R9O A;  2NQI A;  4BOQ A;  1VSN A;  2HH5 A;  5CVM A;  1U9W A;  1THE A;  4WA6 A;  1PPO A;  4BSQ A;  1TL9 A;  4X6I A;  2AGA A;  2ACT A;  2HHN A;  4BOP A;  5JA7 A;  3NHE A;  1YK7 A;  3BC3 A;  1EWL A;  1NPZ A;  2PAD A;  2BU3 A;  3TMP A;  1CV8 A;  2P7U A;  5EZS A;  1KFX L;  1AIM A;  2AYO A;  3ERV A;  4XZX A;  4YV8 A;  3QT4 A;  4X6H A;  1PIP A;  4YYR A;  2DC6 A;  4HXD B;  4K7C A;  3CBK A;  3IUT A;  4P6E A;  4BPV A;  4YYV A;  5A24 A;  3OF8 A;  1GCB A;  4OW0 A;  4RKX A;  3P5V A;  2DCD A;  3IEJ A;  2C0Y A;  4Q8G A;  2OZ2 A;  1FH0 A;  2FRQ A;  2GFO A;  3KFQ A;  2Y6E A;  3MHS A;  1BP4 A;  1PPN A;  3BBA A;  3IFU A;  2AVW A;  3N3G A;  4N4Z A;  2PNS A;  2FQ9 A;  4PAD A;  1VJV A;  3PSE A;  4OVZ A;  2G8J A;  5FPW A;  3S3R A;  4PP1 A;  3F5V A;  4MM3 B;  3WXE A;  4GUA A;  2FTD A;  1YT7 A;  3LFY A;  3CH2 X;  1QOL A;  4AXM A;  1CB5 A;  1UKF A;  2PBH A;  3CBJ A;  3PBH A;  1U5I A;  3PHX A;  2R9N A;  3KW9 A;  5EZQ A;  2DC9 A;  4PP2 E;  3DF0 A;  4N8W A;  5CVO B;  3C0R A;  1AEC A;  1NL6 A;  2JQG R;  3KWB X;  2YJC A;  2G6D A;  3TRK A;  1U9V A;  4OEM A;  9PAP A;  1HUC B;  1CTE A;  3P5W A;  1AU4 A;  4BS6 A;  3C9E A;  2P86 A;  2Y5B A;  2AU1 A;  4D8I A;  4CDE B;  4XR7 A;  2DJF B;  4CDF B;  1AYU A;  4ZTB A;  3RVX A;  2BTW A;  3PRP A;  1AU3 A;  4D8B A;  2FE8 A;  2IBI A;  3S3Q A;  3MHH A;  3N3K A;  2E02 A;  3E9S A;  3HHA A;  4PI3 A;  1CQD A;  1MEG A;  3MJ5 A;  2BDL A;  3B79 A;  1Q6K A;  1MHW A;  4RF0 A;  3E1Z B;  2DOS A;  1PAD A;  1CJL A;  4QH6 A;  1ICF A;  4BS5 A;  3RVW A;  3BCN A;  3IHP A;  3AI8 A;  4N79 A;  3PNR A;  1U9Q X;  3OIS A;  3RVV A;  1U9X A;  1MDW A;  3TNX A;  4I07 A;  2Z84 A;  2J7Q A;  2B1M A;  4P16 A;  4Q8H A;  3OVZ A;  1SNK A;  2DCA A;  2P0R A;  2DZY A;  3H8C A;  2JTC A;  2ATO A;  4BQV A;  2YJ9 A;  4AXL A;  4DMY A;  3H8B A;  4BOZ A;  1ATK A;  3CH3 X;  1S4V A;  2WBF X;  3HD3 A;  4G54 A;  3I3T A;  4BOU A;  3PHW A;  1BY8 A;  2XU5 A;  3OQC A;  1GLO A;  2E01 A;  1GEC E;  2BDZ A;  4XUI A;  2G8E A;  1AYW A;  3W31 A;  4IP3 A;  3N4C A;  6PAD A;  4QRG A;  2FYE A;  2R9F A;  4YYW A;  4ZUX U;  1M6D A;  3K24 A;  2DCB A;  3BOW A;  4A5U A;  1NLJ A;  2J7Q C;  3KKU A;  2FO5 A;  3MTN A;  3ZUA A;  2AUZ A;  3M99 A;  2FT2 A;  1ZCM A;  5K16 A;  5JH3 A;  4X6J A;  2AUX A;  2HWK A;  3O65 A;  2VHS A;  1STF E;  5F02 A;  3BPM A;  2OUL A;  1PE6 A;  1AYV A;  2YJ8 A;  4FJC A;  3H89 A;  7PCK A;  3MOR A;  1ME4 A; 
#chains in the Genus database with same CATH homology
 1MS6 A;  3H6S A;  1PPD A;  2CB5 A;  1QDQ A;  4QBB A;  2R9M A;  1EWP A;  1PCI A;  1EWO A;  5J94 A;  3F75 A;  1KHQ A;  1CPJ A;  1MIR A;  3O0U A;  1F2A A;  3IV2 A;  3I06 A;  4YYS A;  4W5B A;  2FRA A;  2VHF A;  4NV8 A;  8PCH A;  4KLB A;  2B1N A;  1DF0 A;  4YVA A;  2O6X A;  2ARY A;  1K3B B;  1KFU L;  2CIO A;  3HHI A;  2BSZ A;  3PW3 A;  1ITO A;  2GHU A;  3HWN A;  4B55 A;  3QSD A;  2OP3 A;  1KXR A;  3KSE A;  1MEM A;  1A6R A;  1PBH A;  2DZZ A;  3IOQ A;  4OEL A;  2FUD A;  1BQI A;  2NQG A;  3WXF A;  3LXS A;  1Y08 A;  5PAD A;  1W6F A;  1E2T A;  2AS8 A;  3QJ3 A;  2AYN A;  2IPP B;  5CVN B;  3V6C A;  4W5C A;  1CSB B;  1YVB A;  2YJB A;  1PXV A;  4QRV A;  4HWY A;  1BGO A;  2AIM A;  2DC8 A;  2HXZ A;  2F7D A;  2YJ2 A;  4FIP A;  1NB5 A;  4RY2 A;  3KX1 A;  3USV A;  1O0E A;  3P5U A;  1F29 A;  1X9Y A;  4MSX A;  2XU1 A;  2NQD B;  1PPP A;  1KHP A;  1TU6 A;  1NQC A;  1IWD A;  2G7Y A;  2R9C A;  2XU4 A;  1POP A;  4W4U A;  1ZIV A;  2HD5 A;  2DC7 A;  4MZS A;  1JQP A;  1EWM A;  1XKG A;  1NB3 A;  2E00 A;  5CHV A;  1GMY A;  4YYU A;  3GCB A;  3PDF A;  1W5R A;  4MZO A;  1EF7 A;  3H7D A;  1Y4H A;  3OF9 A;  5EGW A;  2E03 A;  4YYQ A;  3IMA A;  1QXP A;  2XU3 A;  3O1G A;  2R6N A;  2PRE A;  3D6S A;  1F2B A;  1AU0 A;  3BWK A;  3OVX A;  4I05 A;  1YAL A;  1SP4 B;  3KWZ A;  2JQF R;  4CDC B;  1TLO A;  4P6G A;  3BPF A;  1YK8 A;  1CVZ A;  4CZW A;  1F2C A;  2H7J A;  2VFC A;  3WXG A;  1AU2 A;  2DJG B;  2F1G A;  3V6E A;  3K9M A;  2DCC A;  3P5X A;  5CHT A;  2NQA A;  4CDD B;  1ME3 A;  5EF4 A;  4QRX A;  4FK5 A;  3U8E A;  3K8U A;  1QMY A;  4DMX A;  1DEU A;  4I04 A;  1CS8 A;  2R9O A;  2NQI A;  1VSN A;  2HH5 A;  5CVM A;  1U9W A;  1THE A;  4WA6 A;  1PPO A;  4BSQ A;  1TL9 A;  4X6I A;  2ACT A;  2HHN A;  5JA7 A;  3NHE A;  1YK7 A;  3BC3 A;  1EWL A;  1NPZ A;  2PAD A;  1CV8 A;  2P7U A;  1KFX L;  1AIM A;  2AYO A;  3ERV A;  4YV8 A;  3QT4 A;  4X6H A;  1PIP A;  4YYR A;  2DC6 A;  1GX3 A;  2VFB A;  4K7C A;  3CBK A;  3IUT A;  4P6E A;  4BPV A;  4YYV A;  5A24 A;  3OF8 A;  1GCB A;  3P5V A;  2DCD A;  3IEJ A;  2C0Y A;  4Q8G A;  2OZ2 A;  1FH0 A;  2FRQ A;  2GFO A;  3KFQ A;  2Y6E A;  3MHS A;  1BP4 A;  1PPN A;  2AVW A;  3N3G A;  4N4Z A;  2PNS A;  2FQ9 A;  4PAD A;  1VJV A;  5FPW A;  2G8J A;  3S3R A;  4PP1 A;  3F5V A;  3WXE A;  2FTD A;  1W4T A;  1YT7 A;  3LFY A;  3CH2 X;  1QOL A;  4AXM A;  1CB5 A;  2PBH A;  3CBJ A;  3PBH A;  1U5I A;  2R9N A;  3KW9 A;  2DC9 A;  4PP2 E;  3DF0 A;  4N8W A;  5CVO B;  1AEC A;  1NL6 A;  2JQG R;  3KWB X;  2YJC A;  2G6D A;  1U9V A;  4OEM A;  9PAP A;  1HUC B;  1CTE A;  3P5W A;  1AU4 A;  4BS6 A;  3C9E A;  2P86 A;  2Y5B A;  2AU1 A;  4GUZ A;  4CDE B;  4XR7 A;  2DJF B;  4CDF B;  1AYU A;  3RVX A;  1AU3 A;  2IBI A;  3S3Q A;  3MHH A;  3N3K A;  2E02 A;  3HHA A;  4PI3 A;  1CQD A;  1MEG A;  2BDL A;  3B79 A;  1Q6K A;  1MHW A;  3E1Z B;  1PAD A;  1CJL A;  4QH6 A;  1ICF A;  4BS5 A;  3RVW A;  3BCN A;  3IHP A;  3AI8 A;  4N79 A;  3PNR A;  1U9Q X;  3OIS A;  3RVV A;  1U9X A;  1MDW A;  3TNX A;  4I07 A;  2B1M A;  4Q8H A;  3OVZ A;  4NV7 A;  1SNK A;  2DCA A;  2P0R A;  2DZY A;  3H8C A;  2ATO A;  4BQV A;  2YJ9 A;  4AXL A;  4DMY A;  3H8B A;  3D9W A;  1ATK A;  3CH3 X;  3LTW A;  1S4V A;  2WBF X;  3HD3 A;  4G54 A;  3I3T A;  1BY8 A;  2XU5 A;  1GLO A;  2E01 A;  1GEC E;  2BDZ A;  4XUI A;  2G8E A;  1AYW A;  3N4C A;  6PAD A;  4QRG A;  2FYE A;  2R9F A;  4YYW A;  4ZUX U;  1M6D A;  3K24 A;  2DCB A;  3BOW A;  1NLJ A;  3KKU A;  2FO5 A;  3MTN A;  3ZUA A;  2AUZ A;  3M99 A;  2FT2 A;  1ZCM A;  5K16 A;  5JH3 A;  4X6J A;  2AUX A;  4BGF A;  2VHS A;  1STF E;  5F02 A;  3BPM A;  2OUL A;  4C5P A;  1PE6 A;  1AYV A;  2YJ8 A;  4FJC A;  3H89 A;  7PCK A;  3MOR A;  1ME4 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...