3IV2A

Crystal structure of mature apo-cathepsin l c25a mutant
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
219
structure length
219
Chain Sequence
b'PRSVDWREKGYVTPVKNQGQCGSAWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Cathepsin L1
publication title Structural basis for the recognition and cleavage of histone H3 by cathepsin L.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 61
structure length 219
sequence length 219
chains with identical sequence B
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2009-08-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3iv2A00
1NL6A 1O0EA 1HUCB 7PCKA 3U8EA 4N79A 2B1NA 2AUXA 2HHNA 3RVVA 1PPOA 3BWKA 1PE6A 1EWOA 1AU4A 3P5VA 1ITOA 1ICFA 2DCDA 4DMYA 4I05A 2ARYA 2E00A 3N4CA 3OVZA 5CVOB 2NQAA 2DC9A 2DJGB 4CZWA 1PXVA 2DZZA 4YYQA 4YYSA 1EWPA 1NB3A 1AYVA 4AXLA 2OP3A 1CS8A 1YT7A 3PDFA 3V6EA 3MHHA 5JA7A 2JQGR 5J94A 3IHPA 4XUIA 2Y6EA 3IUTA 1QMYA 4W5CA 4MZSA 2R6NA 2NQDB 2F7DA 2AS8A 3D6SA 2G6DA 3NHEA 1AYUA 1BGOA 4KLBA 3WXEA 3BC3A 3DF0A 3MORA 5CHTA 4BSQA 4YYWA 2XU1A 1NPZA 2WBFX 6PADA 3S3QA 1PPDA 1QXPA 2NQGA 1ME4A 2HXZA 3LFYA 9PAPA 3OVXA 1TLOA 3HHIA 2O6XA 2BDZA 3P5XA 3N3KA 1A6RA 3IMAA 1CQDA 1M6DA 3N3GA 2DC6A 3CBKA 5FPWA 4W4UA 1QOLA 1EWMA 2YJ9A 1U9QX 1Y08A 3MHSA 2YJCA 3F5VA 2G8EA 3K9MA 2CIOA 5JH3A 2JQFR 3LXSA 1AU2A 2HD5A 4AXMA 2IBIA 3C9EA 5EF4A 2YJBA 5PADA 1U9VA 2XU5A 1S4VA 1JQPA 3USVA 2OZ2A 4QRGA 1F29A 2DC7A 5CHVA 2PNSA 3ZUAA 1NQCA 1CPJA 2AYOA 1ZCMA 4BPVA 8PCHA 3QSDA 3F75A 3KSEA 2FRQA 1IWDA 2P86A 1MDWA 4FIPA 3ERVA 1THEA 4RY2A 4Q8GA 2DC8A 1MHWA 1XKGA 4QBBA 4CDFB 1U9WA 1DF0A 3RVXA 1GECE 2XU4A 3QT4A 3K24A 2P7UA 1AU0A 1CV8A 2BDLA 4QH6A 1PADA 3OF8A 1ZIVA 4WA6A 3WXFA 1SP4B 1BY8A 1GLOA 1K3BB 2R9CA 2NQIA 3RVWA 3WXGA 4FJCA 2R9OA 2E02A 4PADA 2E01A 3H6SA 1YK8A 1F2AA 2R9MA 2ATOA 3P5WA 4Q8HA 4BS6A 1CTEA 2YJ2A 4QRVA 1F2BA 4CDDB 4N8WA 3GCBA 1NLJA 1KFXL 2FTDA 1CJLA 1PCIA 4PP1A 1TL9A 4YYUA 3OF9A 1POPA 2FRAA 4HWYA 1GCBA 1Q6KA 3KWZA 2P0RA 2AU1A 3KKUA 3KWBX 3PW3A 1STFE 3H89A 1U5IA 3IV2A 5F02A 4YVAA 2YJ8A 4W5BA 3I3TA 2FYEA 1SNKA 4DMXA 1Y4HA 4CDEB 1CVZA 2PADA 1CB5A 3V6CA 1KXRA 2OULA 3BOWA 1BQIA 3H8BA 1VSNA 2DJFB 4X6JA 2GHUA 2R9FA 3BPMA 1AIMA 1EWLA 1U9XA 3IOQA 2FUDA 2FT2A 3S3RA 5CVNB 2PBHA 4N4ZA 2ACTA 2FQ9A 1VJVA 3M99A 3H7DA 1DEUA 2Y5BA 4ZUXU 3TNXA 4FK5A 1KFUL 3K8UA 3KFQA 2PREA 3B79A 1BP4A 2G7YA 3CBJA 1MEGA 3IEJA 2AIMA 1TU6A 3BPFA 3O1GA 1X9YA 3PNRA 3P5UA 2AUZA 3CH3X 3HD3A 4PI3A 4PP2E 4BS5A 2AVWA 2DCCA 2IPPB 1KHQA 4MSXA 4OEMA 4YYRA 1MS6A 2VHFA 4K7CA 3CH2X 1AU3A 1YK7A 4MZOA 4P6GA 1AECA 2DCAA 4XR7A 4OELA 1ME3A 3HWNA 3BCNA 3I06A 1QDQA 1PIPA 4P6EA 4X6IA 1NB5A 4X6HA 2G8JA 3QJ3A 1MIRA 2DZYA 2FO5A 4YV8A 1EF7A 4CDCB 5K16A 1CSBB 1KHPA 1F2CA 2HH5A 2DCBA 4BQVA 1MEMA 2VHSA 3H8CA 1GMYA 2CB5A 2B1MA 4QRXA 1PBHA 1FH0A 3O0UA 1YALA 3KX1A 4I07A 3KW9A 1AYWA 1PPPA 2GFOA 4YYVA 2F1GA 2XU3A 4G54A 4I04A 3E1ZB 2H7JA 3MTNA 5A24A 1ATKA 3PBHA 1PPNA 2AYNA 2E03A 3OISA 2C0YA 2R9NA 3AI8A 5EGWA 1YVBA 3HHAA 5CVMA
chains in the Genus database with same CATH superfamily
1NL6A 1O0EA 1HUCB 7PCKA 3U8EA 4N79A 2B1NA 3TRKA 2AUXA 2HHNA 4MI7A 3RVVA 1PPOA 3BWKA 1PE6A 1EWOA 3PHXA 1AU4A 3P5VA 1ITOA 5EZSA 1ICFA 2DCDA 4DMYA 4I05A 2ARYA 2E00A 3PHUA 3N4CA 3OVZA 5CVOB 2NQAA 4BOZA 2DC9A 3IFUA 3MTVA 2DJGB 4CZWA 1PXVA 2DZZA 4YYQA 4YYSA 1EWPA 1NB3A 1AYVA 4AXLA 2OP3A 1CS8A 1YT7A 3PDFA 3V6EA 3MHHA 5JA7A 2JQGR 5J94A 3IHPA 4XUIA 2Y6EA 3IUTA 3OQCA 1QMYA 4W5CA 3BB7A 4MZSA 2BTWB 2R6NA 2NQDB 2F7DA 2AS8A 3D6SA 2G6DA 5JZEA 5KO3A 3NHEA 1AYUA 1BGOA 4PT5A 4KLBA 3WXEA 3BC3A 3DF0A 3MORA 5CHTA 3ZNHA 4BSQA 4YYWA 2XU1A 1NPZA 2WBFX 6PADA 3S3QA 1PPDA 3B21A 1QXPA 2Z84A 2NQGA 1ME4A 2HXZA 3LFYA 9PAPA 3OVXA 1TLOA 3HHIA 2O6XA 2BDZA 3P5XA 3N3KA 1A6RA 3IMAA 1CQDA 1M6DA 3N3GA 4GUAA 2DC6A 3CBKA 4BOSA 5FPWA 4W4UA 1QOLA 4MM3B 1EWMA 2YJ9A 1U9QX 1Y08A 3MHSA 4D8EA 4A5UA 2YJCA 3F5VA 2G8EA 4OVZA 3K9MA 2CIOA 5JH3A 2JQFR 3LXSA 1AU2A 2HD5A 4AXMA 3PT2A 2IBIA 1PVJA 3C9EA 4HXDB 5EF4A 3BBAA 2YJBA 5PADA 1U9VA 2XU5A 3PRMA 1S4VA 1JQPA 3USVA 2OZ2A 4QRGA 1F29A 2DC7A 4XZXA 3MP2A 5CHVA 2PNSA 3ZUAA 1NQCA 2UZJA 1CPJA 2AYOA 1ZCMA 4BPVA 8PCHA 3QSDA 3F75A 3KSEA 2FRQA 1IWDA 2P86A 1MDWA 4FIPA 3ERVA 1THEA 4RY2A 4Q8GA 2DC8A 4RNAA 1MHWA 1XKGA 4QBBA 4D8IA 4CDFB 1U9WA 1DF0A 3E9SA 3RVXA 1GECE 4RKXA 2XU4A 3QT4A 3K24A 2P7UA 3C0RA 1AU0A 1CV8A 4REZA 3TMPA 5EZQA 2BDLA 4QH6A 1PADA 4WURA 3OF8A 1ZIVA 4WA6A 3WXFA 1SP4B 1BY8A 1GLOA 1K3BB 2R9CA 2NQIA 3RVWA 3PRPA 4FJCA 3WXGA 2R9OA 2E02A 4PADA 2E01A 3H6SA 1YK8A 1F2AA 2R9MA 2ATOA 5E6JA 4OW0A 3P5WA 4Q8HA 4BS6A 1CTEA 2YJ2A 4QRVA 2J7QA 1F2BA 4CDDB 4N8WA 3GCBA 1NLJA 1KFXL 2FTDA 2DOSA 1CJLA 1PCIA 4PP1A 1TL9A 4YYUA 3OF9A 2JTCA 1POPA 2FRAA 4P16A 4HWYA 1GCBA 1UKFA 1Q6KA 3KWZA 3PHWA 2P0RA 2AU1A 3KKUA 3KWBX 3PW3A 4OVZB 1STFE 3H89A 1U5IA 3IV2A 2JRIA 4BOUA 5F02A 4YVAA 2YJ8A 4W5BA 3I3TA 2FYEA 1SNKA 4DMXA 1Y4HA 4CDEB 1CVZA 2PADA 1CB5A 3V6CA 1KXRA 2OULA 3BOWA 3O65A 3PSEA 1BQIA 3H8BA 1VSNA 2DJFB 4X6JA 2GHUA 2R9FA 3BPMA 1AIMA 1EWLA 1U9XA 3IOQA 2FUDA 4R3DA 2AGAA 2FT2A 3S3RA 5CVNB 2PBHA 4N4ZA 2J7QC 2ACTA 2FQ9A 1VJVA 3M99A 3H7DA 2HWKA 1YZBA 1DEUA 2Y5BA 4ZUXU 3W31A 3TNXA 4FK5A 1KFUL 3MJ5A 3K8UA 4BOPA 3KFQA 2PREA 3B79A 1BP4A 2G7YA 3BY4A 3CBJA 1MEGA 3IEJA 2AIMA 1TU6A 3BPFA 3O1GA 1X9YA 3PNRA 3P5UA 2AUZA 3CH3X 3HD3A 4PI3A 4PP2E 4BS5A 2AVWA 2DCCA 2IPPB 1KHQA 4MSXA 4OEMA 4M0WA 4YYRA 4D8BA 1MS6A 2VHFA 4K7CA 3CH2X 1AU3A 1YK7A 4MZOA 4P6GA 1AECA 2DCAA 4RF1A 4RF0A 4XR7A 4OELA 1ME3A 3HWNA 3BCNA 3I06A 1QDQA 1PIPA 2BTWA 4P6EA 4X6IA 1NB5A 4X6HA 2G8JA 3QJ3A 1DKIA 3W30A 1MIRA 2DZYA 2FO5A 4YV8A 1EF7A 4CDCB 5K16A 1CSBB 1KHPA 1F2CA 2HH5A 2DCBA 4BQVA 1MEMA 2VHSA 3H8CA 1GMYA 2CB5A 2B1MA 4QRXA 3RNVA 4IP3A 1PBHA 4BOQA 1FH0A 2FE8A 1YALA 3O0UA 4ZTBA 3KX1A 4I07A 3KW9A 1AYWA 1PPPA 2BU3A 2GFOA 4IUMA 4YYVA 2F1GA 2XU3A 4G54A 4I04A 3E1ZB 2H7JA 3MTNA 5A24A 1ATKA 3PBHA 1PPNA 2AYNA 2E03A 3OISA 2C0YA 2R9NA 3AI8A 5EGWA 1YVBA 3HHAA 5CVMA
chains in the Genus database with same CATH topology
1NL6A 1O0EA 1HUCB 7PCKA 3U8EA 4N79A 2B1NA 2AUXA 2HHNA 3RVVA 2VFCA 1PPOA 3BWKA 1PE6A 1EWOA 1AU4A 3P5VA 1ITOA 3LTWA 1ICFA 2DCDA 4DMYA 4I05A 2ARYA 2E00A 3N4CA 3OVZA 5CVOB 2NQAA 2DC9A 4C5PA 2DJGB 4BGFA 4CZWA 1PXVA 2DZZA 4YYQA 4YYSA 1EWPA 1NB3A 1AYVA 4AXLA 2OP3A 1CS8A 1YT7A 3PDFA 3V6EA 3MHHA 5JA7A 2JQGR 5J94A 3IHPA 4XUIA 2Y6EA 3IUTA 1QMYA 4W5CA 4MZSA 4B55A 2R6NA 2NQDB 2F7DA 2AS8A 3D6SA 2G6DA 3NHEA 1AYUA 3D9WA 1W5RA 1BGOA 4GUZA 4KLBA 3WXEA 3BC3A 3DF0A 3MORA 5CHTA 4BSQA 4YYWA 2XU1A 1NPZA 2WBFX 6PADA 3S3QA 1PPDA 1QXPA 2NQGA 1ME4A 2HXZA 3LFYA 9PAPA 3OVXA 1TLOA 3HHIA 2O6XA 2BDZA 3P5XA 3N3KA 1A6RA 3IMAA 1CQDA 1M6DA 3N3GA 2DC6A 3CBKA 5FPWA 2BSZA 4W4UA 1QOLA 1EWMA 2YJ9A 1U9QX 1Y08A 3MHSA 2YJCA 3F5VA 2G8EA 3K9MA 2CIOA 5JH3A 2JQFR 3LXSA 1AU2A 2HD5A 4AXMA 2IBIA 3C9EA 5EF4A 2YJBA 2VFBA 5PADA 1U9VA 2XU5A 1S4VA 1JQPA 3USVA 2OZ2A 4QRGA 1F29A 2DC7A 5CHVA 2PNSA 3ZUAA 1NQCA 1CPJA 2AYOA 4NV7A 1ZCMA 4BPVA 8PCHA 3QSDA 3F75A 3KSEA 2FRQA 1IWDA 2P86A 1MDWA 4FIPA 3ERVA 1THEA 4RY2A 4Q8GA 2DC8A 1MHWA 1XKGA 4QBBA 4CDFB 1U9WA 1DF0A 3RVXA 1GECE 2XU4A 3QT4A 1W4TA 3K24A 2P7UA 1AU0A 1CV8A 1GX3A 2BDLA 4QH6A 1PADA 3OF8A 1ZIVA 4WA6A 3WXFA 1SP4B 1BY8A 1GLOA 1K3BB 2R9CA 2NQIA 3RVWA 3WXGA 4FJCA 2R9OA 2E02A 4PADA 2E01A 3H6SA 1YK8A 1F2AA 2R9MA 2ATOA 3P5WA 4Q8HA 4BS6A 1CTEA 2YJ2A 4QRVA 1F2BA 4CDDB 4N8WA 3GCBA 1NLJA 1KFXL 2FTDA 1CJLA 1PCIA 4PP1A 1TL9A 4YYUA 3OF9A 1POPA 2FRAA 4HWYA 1GCBA 1Q6KA 3KWZA 2P0RA 2AU1A 3KKUA 3KWBX 3PW3A 1STFE 3H89A 1U5IA 3IV2A 5F02A 4YVAA 2YJ8A 4W5BA 3I3TA 2FYEA 1SNKA 4DMXA 1Y4HA 4CDEB 1CVZA 2PADA 1CB5A 3V6CA 1KXRA 2OULA 3BOWA 1BQIA 3H8BA 1VSNA 2DJFB 4X6JA 2GHUA 2R9FA 3BPMA 1AIMA 1EWLA 1U9XA 3IOQA 2FUDA 2FT2A 3S3RA 5CVNB 2PBHA 4N4ZA 2ACTA 2FQ9A 1VJVA 3M99A 3H7DA 1DEUA 2Y5BA 4NV8A 4ZUXU 3TNXA 4FK5A 1KFUL 3K8UA 3KFQA 2PREA 3B79A 1BP4A 2G7YA 3CBJA 1MEGA 3IEJA 2AIMA 1TU6A 3BPFA 3O1GA 1X9YA 3PNRA 3P5UA 2AUZA 3CH3X 3HD3A 4PI3A 4PP2E 4BS5A 2AVWA 2DCCA 2IPPB 1KHQA 4MSXA 4OEMA 4YYRA 1MS6A 2VHFA 4K7CA 3CH2X 1AU3A 1YK7A 4MZOA 4P6GA 1AECA 2DCAA 4XR7A 4OELA 1ME3A 3HWNA 3BCNA 3I06A 1QDQA 1PIPA 4P6EA 1E2TA 4X6IA 1NB5A 4X6HA 2G8JA 3QJ3A 1MIRA 2DZYA 1W6FA 2FO5A 4YV8A 1EF7A 4CDCB 5K16A 1CSBB 1KHPA 1F2CA 2HH5A 2DCBA 4BQVA 1MEMA 2VHSA 3H8CA 1GMYA 2CB5A 2B1MA 4QRXA 1PBHA 1FH0A 3O0UA 1YALA 3KX1A 4I07A 3KW9A 1AYWA 1PPPA 2GFOA 4YYVA 2F1GA 2XU3A 4G54A 4I04A 3E1ZB 2H7JA 3MTNA 5A24A 1ATKA 3PBHA 1PPNA 2AYNA 2E03A 3OISA 2C0YA 2R9NA 3AI8A 5EGWA 1YVBA 3HHAA 5CVMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NL6 A;  1O0E A;  1HUC B;  7PCK A;  3U8E A;  4N79 A;  2B1N A;  2AUX A;  2HHN A;  3RVV A;  1PPO A;  3BWK A;  1PE6 A;  1EWO A;  1AU4 A;  3P5V A;  1ITO A;  1ICF A;  2DCD A;  4DMY A;  4I05 A;  2ARY A;  2E00 A;  3N4C A;  3OVZ A;  5CVO B;  2NQA A;  2DC9 A;  2DJG B;  4CZW A;  1PXV A;  2DZZ A;  4YYQ A;  4YYS A;  1EWP A;  1NB3 A;  1AYV A;  4AXL A;  2OP3 A;  1CS8 A;  1YT7 A;  3PDF A;  3V6E A;  3MHH A;  5JA7 A;  2JQG R;  5J94 A;  3IHP A;  4XUI A;  2Y6E A;  3IUT A;  1QMY A;  4W5C A;  4MZS A;  2R6N A;  2NQD B;  2F7D A;  2AS8 A;  3D6S A;  2G6D A;  3NHE A;  1AYU A;  1BGO A;  4KLB A;  3WXE A;  3BC3 A;  3DF0 A;  3MOR A;  5CHT A;  4BSQ A;  4YYW A;  2XU1 A;  1NPZ A;  2WBF X;  6PAD A;  3S3Q A;  1PPD A;  1QXP A;  2NQG A;  1ME4 A;  2HXZ A;  3LFY A;  9PAP A;  3OVX A;  1TLO A;  3HHI A;  2O6X A;  2BDZ A;  3P5X A;  3N3K A;  1A6R A;  3IMA A;  1CQD A;  1M6D A;  3N3G A;  2DC6 A;  3CBK A;  5FPW A;  4W4U A;  1QOL A;  1EWM A;  2YJ9 A;  1U9Q X;  1Y08 A;  3MHS A;  2YJC A;  3F5V A;  2G8E A;  3K9M A;  2CIO A;  5JH3 A;  2JQF R;  3LXS A;  1AU2 A;  2HD5 A;  4AXM A;  2IBI A;  3C9E A;  5EF4 A;  2YJB A;  5PAD A;  1U9V A;  2XU5 A;  1S4V A;  1JQP A;  3USV A;  2OZ2 A;  4QRG A;  1F29 A;  2DC7 A;  5CHV A;  2PNS A;  3ZUA A;  1NQC A;  1CPJ A;  2AYO A;  1ZCM A;  4BPV A;  8PCH A;  3QSD A;  3F75 A;  3KSE A;  2FRQ A;  1IWD A;  2P86 A;  1MDW A;  4FIP A;  3ERV A;  1THE A;  4RY2 A;  4Q8G A;  2DC8 A;  1MHW A;  1XKG A;  4QBB A;  4CDF B;  1U9W A;  1DF0 A;  3RVX A;  1GEC E;  2XU4 A;  3QT4 A;  3K24 A;  2P7U A;  1AU0 A;  1CV8 A;  2BDL A;  4QH6 A;  1PAD A;  3OF8 A;  1ZIV A;  4WA6 A;  3WXF A;  1SP4 B;  1BY8 A;  1GLO A;  1K3B B;  2R9C A;  2NQI A;  3RVW A;  3WXG A;  4FJC A;  2R9O A;  2E02 A;  4PAD A;  2E01 A;  3H6S A;  1YK8 A;  1F2A A;  2R9M A;  2ATO A;  3P5W A;  4Q8H A;  4BS6 A;  1CTE A;  2YJ2 A;  4QRV A;  1F2B A;  4CDD B;  4N8W A;  3GCB A;  1NLJ A;  1KFX L;  2FTD A;  1CJL A;  1PCI A;  4PP1 A;  1TL9 A;  4YYU A;  3OF9 A;  1POP A;  2FRA A;  4HWY A;  1GCB A;  1Q6K A;  3KWZ A;  2P0R A;  2AU1 A;  3KKU A;  3KWB X;  3PW3 A;  1STF E;  3H89 A;  1U5I A;  3IV2 A;  5F02 A;  4YVA A;  2YJ8 A;  4W5B A;  3I3T A;  2FYE A;  1SNK A;  4DMX A;  1Y4H A;  4CDE B;  1CVZ A;  2PAD A;  1CB5 A;  3V6C A;  1KXR A;  2OUL A;  3BOW A;  1BQI A;  3H8B A;  1VSN A;  2DJF B;  4X6J A;  2GHU A;  2R9F A;  3BPM A;  1AIM A;  1EWL A;  1U9X A;  3IOQ A;  2FUD A;  2FT2 A;  3S3R A;  5CVN B;  2PBH A;  4N4Z A;  2ACT A;  2FQ9 A;  1VJV A;  3M99 A;  3H7D A;  1DEU A;  2Y5B A;  4ZUX U;  3TNX A;  4FK5 A;  1KFU L;  3K8U A;  3KFQ A;  2PRE A;  3B79 A;  1BP4 A;  2G7Y A;  3CBJ A;  1MEG A;  3IEJ A;  2AIM A;  1TU6 A;  3BPF A;  3O1G A;  1X9Y A;  3PNR A;  3P5U A;  2AUZ A;  3CH3 X;  3HD3 A;  4PI3 A;  4PP2 E;  4BS5 A;  2AVW A;  2DCC A;  2IPP B;  1KHQ A;  4MSX A;  4OEM A;  4YYR A;  1MS6 A;  2VHF A;  4K7C A;  3CH2 X;  1AU3 A;  1YK7 A;  4MZO A;  4P6G A;  1AEC A;  2DCA A;  4XR7 A;  4OEL A;  1ME3 A;  3HWN A;  3BCN A;  3I06 A;  1QDQ A;  1PIP A;  4P6E A;  4X6I A;  1NB5 A;  4X6H A;  2G8J A;  3QJ3 A;  1MIR A;  2DZY A;  2FO5 A;  4YV8 A;  1EF7 A;  4CDC B;  5K16 A;  1CSB B;  1KHP A;  1F2C A;  2HH5 A;  2DCB A;  4BQV A;  1MEM A;  2VHS A;  3H8C A;  1GMY A;  2CB5 A;  2B1M A;  4QRX A;  1PBH A;  1FH0 A;  3O0U A;  1YAL A;  3KX1 A;  4I07 A;  3KW9 A;  1AYW A;  1PPP A;  2GFO A;  4YYV A;  2F1G A;  2XU3 A;  4G54 A;  4I04 A;  3E1Z B;  2H7J A;  3MTN A;  5A24 A;  1ATK A;  3PBH A;  1PPN A;  2AYN A;  2E03 A;  3OIS A;  2C0Y A;  2R9N A;  3AI8 A;  5EGW A;  1YVB A;  3HHA A;  5CVM A; 
#chains in the Genus database with same CATH topology
 1NL6 A;  1O0E A;  1HUC B;  7PCK A;  3U8E A;  4N79 A;  2B1N A;  3TRK A;  2AUX A;  2HHN A;  4MI7 A;  3RVV A;  1PPO A;  3BWK A;  1PE6 A;  1EWO A;  3PHX A;  1AU4 A;  3P5V A;  1ITO A;  5EZS A;  1ICF A;  2DCD A;  4DMY A;  4I05 A;  2ARY A;  2E00 A;  3PHU A;  3N4C A;  3OVZ A;  5CVO B;  2NQA A;  4BOZ A;  2DC9 A;  3IFU A;  3MTV A;  2DJG B;  4CZW A;  1PXV A;  2DZZ A;  4YYQ A;  4YYS A;  1EWP A;  1NB3 A;  1AYV A;  4AXL A;  2OP3 A;  1CS8 A;  1YT7 A;  3PDF A;  3V6E A;  3MHH A;  5JA7 A;  2JQG R;  5J94 A;  3IHP A;  4XUI A;  2Y6E A;  3IUT A;  3OQC A;  1QMY A;  4W5C A;  3BB7 A;  4MZS A;  2BTW B;  2R6N A;  2NQD B;  2F7D A;  2AS8 A;  3D6S A;  2G6D A;  5JZE A;  5KO3 A;  3NHE A;  1AYU A;  1BGO A;  4PT5 A;  4KLB A;  3WXE A;  3BC3 A;  3DF0 A;  3MOR A;  5CHT A;  3ZNH A;  4BSQ A;  4YYW A;  2XU1 A;  1NPZ A;  2WBF X;  6PAD A;  3S3Q A;  1PPD A;  3B21 A;  1QXP A;  2Z84 A;  2NQG A;  1ME4 A;  2HXZ A;  3LFY A;  9PAP A;  3OVX A;  1TLO A;  3HHI A;  2O6X A;  2BDZ A;  3P5X A;  3N3K A;  1A6R A;  3IMA A;  1CQD A;  1M6D A;  3N3G A;  4GUA A;  2DC6 A;  3CBK A;  4BOS A;  5FPW A;  4W4U A;  1QOL A;  4MM3 B;  1EWM A;  2YJ9 A;  1U9Q X;  1Y08 A;  3MHS A;  4D8E A;  4A5U A;  2YJC A;  3F5V A;  2G8E A;  4OVZ A;  3K9M A;  2CIO A;  5JH3 A;  2JQF R;  3LXS A;  1AU2 A;  2HD5 A;  4AXM A;  3PT2 A;  2IBI A;  1PVJ A;  3C9E A;  4HXD B;  5EF4 A;  3BBA A;  2YJB A;  5PAD A;  1U9V A;  2XU5 A;  3PRM A;  1S4V A;  1JQP A;  3USV A;  2OZ2 A;  4QRG A;  1F29 A;  2DC7 A;  4XZX A;  3MP2 A;  5CHV A;  2PNS A;  3ZUA A;  1NQC A;  2UZJ A;  1CPJ A;  2AYO A;  1ZCM A;  4BPV A;  8PCH A;  3QSD A;  3F75 A;  3KSE A;  2FRQ A;  1IWD A;  2P86 A;  1MDW A;  4FIP A;  3ERV A;  1THE A;  4RY2 A;  4Q8G A;  2DC8 A;  4RNA A;  1MHW A;  1XKG A;  4QBB A;  4D8I A;  4CDF B;  1U9W A;  1DF0 A;  3E9S A;  3RVX A;  1GEC E;  4RKX A;  2XU4 A;  3QT4 A;  3K24 A;  2P7U A;  3C0R A;  1AU0 A;  1CV8 A;  4REZ A;  3TMP A;  5EZQ A;  2BDL A;  4QH6 A;  1PAD A;  4WUR A;  3OF8 A;  1ZIV A;  4WA6 A;  3WXF A;  1SP4 B;  1BY8 A;  1GLO A;  1K3B B;  2R9C A;  2NQI A;  3RVW A;  3PRP A;  4FJC A;  3WXG A;  2R9O A;  2E02 A;  4PAD A;  2E01 A;  3H6S A;  1YK8 A;  1F2A A;  2R9M A;  2ATO A;  5E6J A;  4OW0 A;  3P5W A;  4Q8H A;  4BS6 A;  1CTE A;  2YJ2 A;  4QRV A;  2J7Q A;  1F2B A;  4CDD B;  4N8W A;  3GCB A;  1NLJ A;  1KFX L;  2FTD A;  2DOS A;  1CJL A;  1PCI A;  4PP1 A;  1TL9 A;  4YYU A;  3OF9 A;  2JTC A;  1POP A;  2FRA A;  4P16 A;  4HWY A;  1GCB A;  1UKF A;  1Q6K A;  3KWZ A;  3PHW A;  2P0R A;  2AU1 A;  3KKU A;  3KWB X;  3PW3 A;  4OVZ B;  1STF E;  3H89 A;  1U5I A;  3IV2 A;  2JRI A;  4BOU A;  5F02 A;  4YVA A;  2YJ8 A;  4W5B A;  3I3T A;  2FYE A;  1SNK A;  4DMX A;  1Y4H A;  4CDE B;  1CVZ A;  2PAD A;  1CB5 A;  3V6C A;  1KXR A;  2OUL A;  3BOW A;  3O65 A;  3PSE A;  1BQI A;  3H8B A;  1VSN A;  2DJF B;  4X6J A;  2GHU A;  2R9F A;  3BPM A;  1AIM A;  1EWL A;  1U9X A;  3IOQ A;  2FUD A;  4R3D A;  2AGA A;  2FT2 A;  3S3R A;  5CVN B;  2PBH A;  4N4Z A;  2J7Q C;  2ACT A;  2FQ9 A;  1VJV A;  3M99 A;  3H7D A;  2HWK A;  1YZB A;  1DEU A;  2Y5B A;  4ZUX U;  3W31 A;  3TNX A;  4FK5 A;  1KFU L;  3MJ5 A;  3K8U A;  4BOP A;  3KFQ A;  2PRE A;  3B79 A;  1BP4 A;  2G7Y A;  3BY4 A;  3CBJ A;  1MEG A;  3IEJ A;  2AIM A;  1TU6 A;  3BPF A;  3O1G A;  1X9Y A;  3PNR A;  3P5U A;  2AUZ A;  3CH3 X;  3HD3 A;  4PI3 A;  4PP2 E;  4BS5 A;  2AVW A;  2DCC A;  2IPP B;  1KHQ A;  4MSX A;  4OEM A;  4M0W A;  4YYR A;  4D8B A;  1MS6 A;  2VHF A;  4K7C A;  3CH2 X;  1AU3 A;  1YK7 A;  4MZO A;  4P6G A;  1AEC A;  2DCA A;  4RF1 A;  4RF0 A;  4XR7 A;  4OEL A;  1ME3 A;  3HWN A;  3BCN A;  3I06 A;  1QDQ A;  1PIP A;  2BTW A;  4P6E A;  4X6I A;  1NB5 A;  4X6H A;  2G8J A;  3QJ3 A;  1DKI A;  3W30 A;  1MIR A;  2DZY A;  2FO5 A;  4YV8 A;  1EF7 A;  4CDC B;  5K16 A;  1CSB B;  1KHP A;  1F2C A;  2HH5 A;  2DCB A;  4BQV A;  1MEM A;  2VHS A;  3H8C A;  1GMY A;  2CB5 A;  2B1M A;  4QRX A;  3RNV A;  4IP3 A;  1PBH A;  4BOQ A;  1FH0 A;  2FE8 A;  1YAL A;  3O0U A;  4ZTB A;  3KX1 A;  4I07 A;  3KW9 A;  1AYW A;  1PPP A;  2BU3 A;  2GFO A;  4IUM A;  4YYV A;  2F1G A;  2XU3 A;  4G54 A;  4I04 A;  3E1Z B;  2H7J A;  3MTN A;  5A24 A;  1ATK A;  3PBH A;  1PPN A;  2AYN A;  2E03 A;  3OIS A;  2C0Y A;  2R9N A;  3AI8 A;  5EGW A;  1YVB A;  3HHA A;  5CVM A; 
#chains in the Genus database with same CATH homology
 1NL6 A;  1O0E A;  1HUC B;  7PCK A;  3U8E A;  4N79 A;  2B1N A;  2AUX A;  2HHN A;  3RVV A;  2VFC A;  1PPO A;  3BWK A;  1PE6 A;  1EWO A;  1AU4 A;  3P5V A;  1ITO A;  3LTW A;  1ICF A;  2DCD A;  4DMY A;  4I05 A;  2ARY A;  2E00 A;  3N4C A;  3OVZ A;  5CVO B;  2NQA A;  2DC9 A;  4C5P A;  2DJG B;  4BGF A;  4CZW A;  1PXV A;  2DZZ A;  4YYQ A;  4YYS A;  1EWP A;  1NB3 A;  1AYV A;  4AXL A;  2OP3 A;  1CS8 A;  1YT7 A;  3PDF A;  3V6E A;  3MHH A;  5JA7 A;  2JQG R;  5J94 A;  3IHP A;  4XUI A;  2Y6E A;  3IUT A;  1QMY A;  4W5C A;  4MZS A;  4B55 A;  2R6N A;  2NQD B;  2F7D A;  2AS8 A;  3D6S A;  2G6D A;  3NHE A;  1AYU A;  3D9W A;  1W5R A;  1BGO A;  4GUZ A;  4KLB A;  3WXE A;  3BC3 A;  3DF0 A;  3MOR A;  5CHT A;  4BSQ A;  4YYW A;  2XU1 A;  1NPZ A;  2WBF X;  6PAD A;  3S3Q A;  1PPD A;  1QXP A;  2NQG A;  1ME4 A;  2HXZ A;  3LFY A;  9PAP A;  3OVX A;  1TLO A;  3HHI A;  2O6X A;  2BDZ A;  3P5X A;  3N3K A;  1A6R A;  3IMA A;  1CQD A;  1M6D A;  3N3G A;  2DC6 A;  3CBK A;  5FPW A;  2BSZ A;  4W4U A;  1QOL A;  1EWM A;  2YJ9 A;  1U9Q X;  1Y08 A;  3MHS A;  2YJC A;  3F5V A;  2G8E A;  3K9M A;  2CIO A;  5JH3 A;  2JQF R;  3LXS A;  1AU2 A;  2HD5 A;  4AXM A;  2IBI A;  3C9E A;  5EF4 A;  2YJB A;  2VFB A;  5PAD A;  1U9V A;  2XU5 A;  1S4V A;  1JQP A;  3USV A;  2OZ2 A;  4QRG A;  1F29 A;  2DC7 A;  5CHV A;  2PNS A;  3ZUA A;  1NQC A;  1CPJ A;  2AYO A;  4NV7 A;  1ZCM A;  4BPV A;  8PCH A;  3QSD A;  3F75 A;  3KSE A;  2FRQ A;  1IWD A;  2P86 A;  1MDW A;  4FIP A;  3ERV A;  1THE A;  4RY2 A;  4Q8G A;  2DC8 A;  1MHW A;  1XKG A;  4QBB A;  4CDF B;  1U9W A;  1DF0 A;  3RVX A;  1GEC E;  2XU4 A;  3QT4 A;  1W4T A;  3K24 A;  2P7U A;  1AU0 A;  1CV8 A;  1GX3 A;  2BDL A;  4QH6 A;  1PAD A;  3OF8 A;  1ZIV A;  4WA6 A;  3WXF A;  1SP4 B;  1BY8 A;  1GLO A;  1K3B B;  2R9C A;  2NQI A;  3RVW A;  3WXG A;  4FJC A;  2R9O A;  2E02 A;  4PAD A;  2E01 A;  3H6S A;  1YK8 A;  1F2A A;  2R9M A;  2ATO A;  3P5W A;  4Q8H A;  4BS6 A;  1CTE A;  2YJ2 A;  4QRV A;  1F2B A;  4CDD B;  4N8W A;  3GCB A;  1NLJ A;  1KFX L;  2FTD A;  1CJL A;  1PCI A;  4PP1 A;  1TL9 A;  4YYU A;  3OF9 A;  1POP A;  2FRA A;  4HWY A;  1GCB A;  1Q6K A;  3KWZ A;  2P0R A;  2AU1 A;  3KKU A;  3KWB X;  3PW3 A;  1STF E;  3H89 A;  1U5I A;  3IV2 A;  5F02 A;  4YVA A;  2YJ8 A;  4W5B A;  3I3T A;  2FYE A;  1SNK A;  4DMX A;  1Y4H A;  4CDE B;  1CVZ A;  2PAD A;  1CB5 A;  3V6C A;  1KXR A;  2OUL A;  3BOW A;  1BQI A;  3H8B A;  1VSN A;  2DJF B;  4X6J A;  2GHU A;  2R9F A;  3BPM A;  1AIM A;  1EWL A;  1U9X A;  3IOQ A;  2FUD A;  2FT2 A;  3S3R A;  5CVN B;  2PBH A;  4N4Z A;  2ACT A;  2FQ9 A;  1VJV A;  3M99 A;  3H7D A;  1DEU A;  2Y5B A;  4NV8 A;  4ZUX U;  3TNX A;  4FK5 A;  1KFU L;  3K8U A;  3KFQ A;  2PRE A;  3B79 A;  1BP4 A;  2G7Y A;  3CBJ A;  1MEG A;  3IEJ A;  2AIM A;  1TU6 A;  3BPF A;  3O1G A;  1X9Y A;  3PNR A;  3P5U A;  2AUZ A;  3CH3 X;  3HD3 A;  4PI3 A;  4PP2 E;  4BS5 A;  2AVW A;  2DCC A;  2IPP B;  1KHQ A;  4MSX A;  4OEM A;  4YYR A;  1MS6 A;  2VHF A;  4K7C A;  3CH2 X;  1AU3 A;  1YK7 A;  4MZO A;  4P6G A;  1AEC A;  2DCA A;  4XR7 A;  4OEL A;  1ME3 A;  3HWN A;  3BCN A;  3I06 A;  1QDQ A;  1PIP A;  4P6E A;  1E2T A;  4X6I A;  1NB5 A;  4X6H A;  2G8J A;  3QJ3 A;  1MIR A;  2DZY A;  1W6F A;  2FO5 A;  4YV8 A;  1EF7 A;  4CDC B;  5K16 A;  1CSB B;  1KHP A;  1F2C A;  2HH5 A;  2DCB A;  4BQV A;  1MEM A;  2VHS A;  3H8C A;  1GMY A;  2CB5 A;  2B1M A;  4QRX A;  1PBH A;  1FH0 A;  3O0U A;  1YAL A;  3KX1 A;  4I07 A;  3KW9 A;  1AYW A;  1PPP A;  2GFO A;  4YYV A;  2F1G A;  2XU3 A;  4G54 A;  4I04 A;  3E1Z B;  2H7J A;  3MTN A;  5A24 A;  1ATK A;  3PBH A;  1PPN A;  2AYN A;  2E03 A;  3OIS A;  2C0Y A;  2R9N A;  3AI8 A;  5EGW A;  1YVB A;  3HHA A;  5CVM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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