1BQIA

Use of papain as a model for the structure-based design of cathepsin k inhibitors. crystal structures of two papain inhibitor complexes demonstrate binding to s'-subsites.
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
212
structure length
212
Chain Sequence
IPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNQYSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNQGALLYSIANQPVSVVLQAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYGPNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Use of papain as a model for the structure-based design of cathepsin K inhibitors: crystal structures of two papain-inhibitor complexes demonstrate binding to S'-subsites.
pubmed doi rcsb
molecule keywords PAPAIN
molecule tags Hydrolase
total genus 62
structure length 212
sequence length 212
ec nomenclature ec 3.4.22.2: Papain.
pdb deposition date 1998-08-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1bqiA00
1NB3A 3K8UA 4PP1A 5JA7A 1M6DA 2P0RA 3H6SA 1CQDA 1EWOA 1CB5A 1ME4A 2BDZA 2AIMA 3WXEA 3I3TA 3OISA 1MEMA 4PP2E 4BQVA 4AXMA 1PE6A 2YJ9A 2G8JA 2WBFX 3LXSA 3P5VA 1TLOA 1U9WA 1MIRA 1CS8A 4FIPA 2DZYA 3C9EA 4I07A 4I05A 2IPPB 1CVZA 3HWNA 4KLBA 1TL9A 3IV2A 1AU0A 2DJGB 3LFYA 4QRXA 5JH3A 1Y08A 3I06A 1NLJA 4FK5A 3OVXA 1F2CA 4PADA 4N4ZA 1QOLA 1U9QX 2FRQA 3CH3X 2AU1A 2YJBA 2PNSA 3S3RA 2FO5A 3GCBA 5F02A 5PADA 5A24A 1ATKA 2B1MA 4MSXA 2AUZA 2FT2A 2FRAA 1ICFA 2HD5A 4OELA 2AS8A 3U8EA 2NQAA 1AYUA 3IOQA 2XU1A 3CBJA 2JQFR 3IEJA 1F2AA 3KSEA 3NHEA 3KKUA 3HHIA 1PADA 1EWMA 4N79A 1QXPA 3HD3A 3RVVA 3MHHA 1YK7A 2E03A 1AYWA 1GMYA 1K3BB 1QMYA 1U5IA 2G8EA 2NQDB 3F5VA 3MTNA 3ZUAA 1S4VA 2FTDA 2HH5A 2R9NA 1PIPA 3O0UA 1YVBA 1QDQA 1THEA 1XKGA 1PCIA 2XU3A 1U9VA 1CJLA 2R9MA 3KFQA 3QJ3A 2R6NA 3BPFA 3F75A 2HHNA 3N3GA 4FJCA 1AU4A 3OF9A 3BWKA 3V6EA 2Y5BA 1FH0A 1VSNA 3KWBX 1BGOA 1Q6KA 8PCHA 3M99A 1PPNA 3PDFA 3BC3A 4W4UA 1EF7A 4RY2A 4CDEB 4YYVA 1PPPA 2G6DA 2F7DA 4BS5A 3QT4A 1AIMA 2BDLA 4XR7A 4X6IA 1ME3A 4W5BA 4AXLA 2DCCA 1NQCA 1PPDA 3OVZA 1AECA 3N4CA 1ITOA 3V6CA 3WXGA 4PI3A 1NB5A 2DC7A 3KWZA 3IMAA 4N8WA 9PAPA 1MHWA 2AUXA 2R9CA 2R9FA 4YVAA 2DCBA 2OZ2A 1AU3A 2OULA 2VHSA 2YJCA 1A6RA 3QSDA 1BQIA 3PNRA 1PPOA 1YALA 4BSQA 1GLOA 2PBHA 3ERVA 1JQPA 4ZUXU 4YYUA 3TNXA 2B1NA 4XUIA 1YK8A 2DC9A 4YYQA 3IUTA 4QH6A 1MS6A 3P5XA 3H8CA 4CZWA 2OP3A 2YJ2A 4CDFB 3CBKA 2O6XA 1BP4A 3BOWA 1KXRA 2GHUA 2DCAA 4YYWA 3AI8A 1O0EA 1X9YA 1NPZA 3KX1A 4YYRA 4HWYA 1PXVA 1VJVA 3H7DA 4I04A 1KHQA 1GECE 2NQGA 1BY8A 3USVA 1U9XA 1TU6A 3RVXA 3BPMA 5CVNB 5CHTA 1MEGA 4MZOA 1KFUL 2FQ9A 1AYVA 1CPJA 2NQIA 1SP4B 1MDWA 2AYOA 2ATOA 1EWPA 2DJFB 3P5UA 2DC8A 7PCKA 2JQGR 1DF0A 2E02A 4BS6A 2XU4A 2Y6EA 3P5WA 4G54A 2R9OA 3H8BA 2CB5A 3B79A 2CIOA 4W5CA 2IBIA 2VHFA 1F2BA 1POPA 5EGWA 5CVOB 2XU5A 1KFXL 4OEMA 4YV8A 5K16A 1IWDA 4P6GA 2DCDA 2PADA 2F1GA 1SNKA 2P86A 1PBHA 5CVMA 2H7JA 1YT7A 6PADA 1KHPA 2DC6A 3H89A 4Q8HA 2HXZA 3S3QA 1HUCB 2G7YA 3K24A 4X6JA 1NL6A 4P6EA 3N3KA 2E00A 1Y4HA 2AYNA 1AU2A 1CTEA 1STFE 1F29A 2AVWA 3MORA 4K7CA 1ZIVA 4DMXA 3PBHA 3KW9A 3OF8A 5FPWA 3MHSA 4QBBA 1GCBA 4QRGA 2ACTA 2E01A 4CDCB 1EWLA 4BPVA 4Q8GA 5CHVA 3CH2X 3WXFA 2C0YA 3O1GA 3IHPA 3PW3A 5EF4A 1DEUA 3E1ZB 3RVWA 3HHAA 3BCNA 4YYSA 2P7UA 4DMYA 1CV8A 1ZCMA 4WA6A 2PREA 3K9MA 3D6SA 2ARYA 4X6HA 2FUDA 5J94A 4QRVA 2DZZA 4MZSA 2GFOA 4CDDB 2YJ8A 3DF0A 1CSBB 2FYEA
chains in the Genus database with same CATH superfamily
1NB3A 3MTVA 3K8UA 4PP1A 5JA7A 1M6DA 2P0RA 3H6SA 2JTCA 1CQDA 1EWOA 1CB5A 1ME4A 2BDZA 2AIMA 3WXEA 2FE8A 2BTWB 3I3TA 3OISA 1MEMA 4PP2E 4BOSA 4BQVA 4AXMA 1PE6A 3O65A 2YJ9A 2G8JA 2WBFX 3LXSA 4BOPA 3P5VA 1TLOA 1U9WA 1MIRA 1CS8A 4FIPA 1YZBA 2DZYA 3C9EA 4I07A 4I05A 3W30A 2IPPB 1CVZA 3HWNA 3PSEA 4KLBA 1TL9A 3IV2A 1AU0A 2DJGB 3LFYA 4QRXA 5JH3A 2J7QA 1Y08A 3I06A 1NLJA 4FK5A 3OVXA 1F2CA 4PADA 5JZEA 4N4ZA 1QOLA 1U9QX 2FRQA 3CH3X 2AU1A 5E6JA 4IP3A 2YJBA 2PNSA 3S3RA 2FO5A 3GCBA 5F02A 5PADA 5A24A 1ATKA 3MP2A 2B1MA 4MSXA 2AUZA 2FT2A 4D8BA 3BBAA 2FRAA 1ICFA 2HD5A 4OELA 2AS8A 3U8EA 2NQAA 3C0RA 1AYUA 3IOQA 2XU1A 3CBJA 2JQFR 3IEJA 1F2AA 3KSEA 3PHXA 2DOSA 3NHEA 3KKUA 3HHIA 1PADA 4GUAA 1EWMA 4N79A 1QXPA 3HD3A 3RVVA 2UZJA 3MHHA 1YK7A 2E03A 1AYWA 1GMYA 1K3BB 4RF0A 1QMYA 3PRMA 4OW0A 1U5IA 2G8EA 2NQDB 3F5VA 3MTNA 3PRPA 3ZUAA 1S4VA 2FTDA 2HH5A 2R9NA 1PIPA 3O0UA 1YVBA 1QDQA 1THEA 4PT5A 1XKGA 1PCIA 2XU3A 1U9VA 1CJLA 2R9MA 3KFQA 2AGAA 3QJ3A 2R6NA 4D8EA 2HWKA 3BPFA 3F75A 2HHNA 3N3GA 4FJCA 1AU4A 3OF9A 3BWKA 3V6EA 2Y5BA 1FH0A 1VSNA 4A5UA 3KWBX 1BGOA 1Q6KA 8PCHA 3M99A 1PPNA 3PDFA 3BC3A 4W4UA 4BOZA 1EF7A 4RY2A 4CDEB 4YYVA 1PPPA 2G6DA 2F7DA 4BS5A 3QT4A 1AIMA 2BDLA 4XR7A 4X6IA 1ME3A 4W5BA 4AXLA 2DCCA 3OQCA 4RNAA 1NQCA 1PPDA 3OVZA 3TRKA 1AECA 3N4CA 1ITOA 3V6CA 3PT2A 4REZA 4PI3A 3WXGA 1NB5A 5EZSA 2DC7A 3KWZA 3IMAA 4N8WA 4OVZA 9PAPA 1MHWA 2AUXA 2R9CA 2R9FA 4YVAA 2DCBA 2OZ2A 1AU3A 2OULA 2VHSA 2YJCA 1A6RA 4MI7A 3QSDA 1BQIA 4XZXA 3PNRA 3ZNHA 1PPOA 1YALA 4BSQA 4D8IA 1GLOA 2PBHA 3ERVA 4ZTBA 1JQPA 4ZUXU 4YYUA 3B21A 3W31A 3TNXA 2B1NA 4HXDB 4RKXA 4XUIA 1YK8A 2DC9A 4YYQA 3IUTA 4QH6A 1MS6A 3P5XA 3H8CA 4CZWA 2OP3A 2YJ2A 4CDFB 2BU3A 4P16A 3CBKA 2O6XA 4BOUA 1BP4A 3BOWA 1KXRA 2GHUA 2DCAA 2JRIA 4YYWA 3AI8A 1O0EA 1X9YA 1PVJA 1NPZA 4BOQA 3KX1A 4YYRA 4HWYA 1PXVA 1VJVA 3H7DA 4I04A 1KHQA 1GECE 2NQGA 1BY8A 3USVA 1U9XA 1TU6A 3RVXA 3TMPA 2BTWA 3BPMA 5CVNB 5CHTA 1MEGA 4MZOA 4IUMA 1KFUL 2FQ9A 1AYVA 1CPJA 2NQIA 3PHWA 1SP4B 1MDWA 2AYOA 4M0WA 2ATOA 1EWPA 2DJFB 5KO3A 3P5UA 2DC8A 7PCKA 2JQGR 1DF0A 2E02A 4BS6A 2XU4A 2Y6EA 3P5WA 3MJ5A 4G54A 2R9OA 3H8BA 2CB5A 4R3DA 2Z84A 3B79A 3BY4A 2CIOA 4W5CA 2IBIA 2VHFA 1F2BA 1POPA 5EGWA 5CVOB 4MM3B 2XU5A 4RF1A 1KFXL 4OEMA 4YV8A 5K16A 1IWDA 4P6GA 2DCDA 2PADA 2F1GA 1SNKA 2P86A 1PBHA 5CVMA 2H7JA 3PHUA 1YT7A 6PADA 1KHPA 1UKFA 2DC6A 3H89A 4Q8HA 2HXZA 3S3QA 1HUCB 2G7YA 3K24A 4X6JA 1NL6A 4P6EA 3N3KA 2E00A 1Y4HA 2AYNA 2J7QC 4OVZB 1AU2A 1CTEA 1STFE 1F29A 2AVWA 3MORA 4K7CA 1ZIVA 4DMXA 3PBHA 3KW9A 3E9SA 3OF8A 5FPWA 3MHSA 4QBBA 1GCBA 4QRGA 2ACTA 2E01A 4CDCB 1EWLA 4BPVA 4Q8GA 1DKIA 5CHVA 3CH2X 3WXFA 2C0YA 3RNVA 3O1GA 3IHPA 3PW3A 5EF4A 1DEUA 3E1ZB 4WURA 3RVWA 3HHAA 3BCNA 4YYSA 2P7UA 4DMYA 1CV8A 1ZCMA 5EZQA 4WA6A 2PREA 3IFUA 3K9MA 3D6SA 2ARYA 3BB7A 4X6HA 2FUDA 5J94A 4QRVA 2DZZA 4MZSA 2GFOA 4CDDB 2YJ8A 3DF0A 1CSBB 2FYEA
chains in the Genus database with same CATH topology
1NB3A 3K8UA 4PP1A 5JA7A 1M6DA 2P0RA 3H6SA 1CQDA 1EWOA 1CB5A 1ME4A 2BDZA 2AIMA 3WXEA 3I3TA 3OISA 1MEMA 4PP2E 4BQVA 4AXMA 1PE6A 2YJ9A 2G8JA 2WBFX 3LXSA 3P5VA 1TLOA 1U9WA 1MIRA 1CS8A 4FIPA 2DZYA 3C9EA 4I07A 4I05A 2IPPB 1CVZA 3HWNA 2VFCA 4KLBA 1TL9A 3IV2A 1AU0A 2DJGB 3LFYA 4QRXA 5JH3A 1Y08A 3I06A 2BSZA 1NLJA 4FK5A 3OVXA 1F2CA 4PADA 4N4ZA 1QOLA 1U9QX 2FRQA 3CH3X 2AU1A 2YJBA 2PNSA 3S3RA 4BGFA 2FO5A 3GCBA 5F02A 5PADA 5A24A 1ATKA 2B1MA 3D9WA 4MSXA 2AUZA 2FT2A 2FRAA 1ICFA 2HD5A 4OELA 2AS8A 3U8EA 2NQAA 1AYUA 3IOQA 2XU1A 3CBJA 2JQFR 3IEJA 1F2AA 3KSEA 3NHEA 3KKUA 3HHIA 1PADA 1EWMA 4N79A 1QXPA 3HD3A 3RVVA 3MHHA 1YK7A 2E03A 1AYWA 1GMYA 1K3BB 1QMYA 1U5IA 2G8EA 2NQDB 3F5VA 3MTNA 3ZUAA 1S4VA 2FTDA 2HH5A 2R9NA 1PIPA 3O0UA 1YVBA 1QDQA 1THEA 1XKGA 1PCIA 2XU3A 1U9VA 1CJLA 2R9MA 3KFQA 3QJ3A 2R6NA 3BPFA 3F75A 2HHNA 3N3GA 4FJCA 1AU4A 3OF9A 3BWKA 3V6EA 2Y5BA 1FH0A 1VSNA 3KWBX 1BGOA 1Q6KA 8PCHA 3M99A 1PPNA 3PDFA 3BC3A 4W4UA 1EF7A 4RY2A 4CDEB 4YYVA 1PPPA 2G6DA 2F7DA 4BS5A 3QT4A 1AIMA 2BDLA 4XR7A 4X6IA 1ME3A 4W5BA 4AXLA 2DCCA 1NQCA 1W6FA 1W5RA 1PPDA 3OVZA 1AECA 3N4CA 1W4TA 1ITOA 2VFBA 3V6CA 3WXGA 4PI3A 1NB5A 2DC7A 3KWZA 3IMAA 4N8WA 9PAPA 1MHWA 2AUXA 2R9CA 2R9FA 4YVAA 2DCBA 2OZ2A 1AU3A 2OULA 2VHSA 2YJCA 1A6RA 3QSDA 1BQIA 3PNRA 1PPOA 1YALA 4BSQA 1GLOA 2PBHA 3ERVA 4NV8A 1JQPA 4ZUXU 4YYUA 3TNXA 2B1NA 4XUIA 1YK8A 2DC9A 4YYQA 3IUTA 4QH6A 1MS6A 3P5XA 3H8CA 4CZWA 2OP3A 2YJ2A 4CDFB 3CBKA 2O6XA 1BP4A 3BOWA 1KXRA 2GHUA 2DCAA 4YYWA 3AI8A 1O0EA 1X9YA 1NPZA 3KX1A 4YYRA 4HWYA 1PXVA 1VJVA 3H7DA 4I04A 1KHQA 1GECE 2NQGA 1BY8A 3USVA 1U9XA 1TU6A 3RVXA 3BPMA 5CVNB 5CHTA 1MEGA 4MZOA 1KFUL 2FQ9A 1AYVA 1CPJA 2NQIA 1SP4B 1MDWA 2AYOA 2ATOA 1EWPA 2DJFB 3P5UA 2DC8A 7PCKA 2JQGR 1DF0A 2E02A 4BS6A 2XU4A 2Y6EA 3LTWA 4C5PA 3P5WA 4G54A 2R9OA 3H8BA 2CB5A 3B79A 4B55A 2CIOA 4W5CA 2IBIA 2VHFA 1F2BA 1POPA 5EGWA 5CVOB 2XU5A 1KFXL 4OEMA 4YV8A 5K16A 1IWDA 4P6GA 2DCDA 2PADA 2F1GA 1SNKA 2P86A 1PBHA 5CVMA 2H7JA 1GX3A 1YT7A 6PADA 1KHPA 2DC6A 3H89A 4Q8HA 2HXZA 3S3QA 1HUCB 2G7YA 4NV7A 3K24A 4X6JA 1NL6A 4P6EA 3N3KA 2E00A 1Y4HA 2AYNA 1E2TA 1AU2A 1CTEA 1STFE 1F29A 2AVWA 3MORA 4K7CA 1ZIVA 4DMXA 3PBHA 3KW9A 3OF8A 5FPWA 3MHSA 4QBBA 1GCBA 4QRGA 2ACTA 2E01A 4CDCB 1EWLA 4BPVA 4Q8GA 5CHVA 3CH2X 3WXFA 2C0YA 3O1GA 3IHPA 4GUZA 3PW3A 5EF4A 1DEUA 3E1ZB 3RVWA 3HHAA 3BCNA 4YYSA 2P7UA 4DMYA 1CV8A 1ZCMA 4WA6A 2PREA 3K9MA 3D6SA 2ARYA 4X6HA 2FUDA 5J94A 4QRVA 2DZZA 4MZSA 2GFOA 4CDDB 2YJ8A 3DF0A 1CSBB 2FYEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NB3 A;  3K8U A;  4PP1 A;  5JA7 A;  1M6D A;  2P0R A;  3H6S A;  1CQD A;  1EWO A;  1CB5 A;  1ME4 A;  2BDZ A;  2AIM A;  3WXE A;  3I3T A;  3OIS A;  1MEM A;  4PP2 E;  4BQV A;  4AXM A;  1PE6 A;  2YJ9 A;  2G8J A;  2WBF X;  3LXS A;  3P5V A;  1TLO A;  1U9W A;  1MIR A;  1CS8 A;  4FIP A;  2DZY A;  3C9E A;  4I07 A;  4I05 A;  2IPP B;  1CVZ A;  3HWN A;  4KLB A;  1TL9 A;  3IV2 A;  1AU0 A;  2DJG B;  3LFY A;  4QRX A;  5JH3 A;  1Y08 A;  3I06 A;  1NLJ A;  4FK5 A;  3OVX A;  1F2C A;  4PAD A;  4N4Z A;  1QOL A;  1U9Q X;  2FRQ A;  3CH3 X;  2AU1 A;  2YJB A;  2PNS A;  3S3R A;  2FO5 A;  3GCB A;  5F02 A;  5PAD A;  5A24 A;  1ATK A;  2B1M A;  4MSX A;  2AUZ A;  2FT2 A;  2FRA A;  1ICF A;  2HD5 A;  4OEL A;  2AS8 A;  3U8E A;  2NQA A;  1AYU A;  3IOQ A;  2XU1 A;  3CBJ A;  2JQF R;  3IEJ A;  1F2A A;  3KSE A;  3NHE A;  3KKU A;  3HHI A;  1PAD A;  1EWM A;  4N79 A;  1QXP A;  3HD3 A;  3RVV A;  3MHH A;  1YK7 A;  2E03 A;  1AYW A;  1GMY A;  1K3B B;  1QMY A;  1U5I A;  2G8E A;  2NQD B;  3F5V A;  3MTN A;  3ZUA A;  1S4V A;  2FTD A;  2HH5 A;  2R9N A;  1PIP A;  3O0U A;  1YVB A;  1QDQ A;  1THE A;  1XKG A;  1PCI A;  2XU3 A;  1U9V A;  1CJL A;  2R9M A;  3KFQ A;  3QJ3 A;  2R6N A;  3BPF A;  3F75 A;  2HHN A;  3N3G A;  4FJC A;  1AU4 A;  3OF9 A;  3BWK A;  3V6E A;  2Y5B A;  1FH0 A;  1VSN A;  3KWB X;  1BGO A;  1Q6K A;  8PCH A;  3M99 A;  1PPN A;  3PDF A;  3BC3 A;  4W4U A;  1EF7 A;  4RY2 A;  4CDE B;  4YYV A;  1PPP A;  2G6D A;  2F7D A;  4BS5 A;  3QT4 A;  1AIM A;  2BDL A;  4XR7 A;  4X6I A;  1ME3 A;  4W5B A;  4AXL A;  2DCC A;  1NQC A;  1PPD A;  3OVZ A;  1AEC A;  3N4C A;  1ITO A;  3V6C A;  3WXG A;  4PI3 A;  1NB5 A;  2DC7 A;  3KWZ A;  3IMA A;  4N8W A;  9PAP A;  1MHW A;  2AUX A;  2R9C A;  2R9F A;  4YVA A;  2DCB A;  2OZ2 A;  1AU3 A;  2OUL A;  2VHS A;  2YJC A;  1A6R A;  3QSD A;  1BQI A;  3PNR A;  1PPO A;  1YAL A;  4BSQ A;  1GLO A;  2PBH A;  3ERV A;  1JQP A;  4ZUX U;  4YYU A;  3TNX A;  2B1N A;  4XUI A;  1YK8 A;  2DC9 A;  4YYQ A;  3IUT A;  4QH6 A;  1MS6 A;  3P5X A;  3H8C A;  4CZW A;  2OP3 A;  2YJ2 A;  4CDF B;  3CBK A;  2O6X A;  1BP4 A;  3BOW A;  1KXR A;  2GHU A;  2DCA A;  4YYW A;  3AI8 A;  1O0E A;  1X9Y A;  1NPZ A;  3KX1 A;  4YYR A;  4HWY A;  1PXV A;  1VJV A;  3H7D A;  4I04 A;  1KHQ A;  1GEC E;  2NQG A;  1BY8 A;  3USV A;  1U9X A;  1TU6 A;  3RVX A;  3BPM A;  5CVN B;  5CHT A;  1MEG A;  4MZO A;  1KFU L;  2FQ9 A;  1AYV A;  1CPJ A;  2NQI A;  1SP4 B;  1MDW A;  2AYO A;  2ATO A;  1EWP A;  2DJF B;  3P5U A;  2DC8 A;  7PCK A;  2JQG R;  1DF0 A;  2E02 A;  4BS6 A;  2XU4 A;  2Y6E A;  3P5W A;  4G54 A;  2R9O A;  3H8B A;  2CB5 A;  3B79 A;  2CIO A;  4W5C A;  2IBI A;  2VHF A;  1F2B A;  1POP A;  5EGW A;  5CVO B;  2XU5 A;  1KFX L;  4OEM A;  4YV8 A;  5K16 A;  1IWD A;  4P6G A;  2DCD A;  2PAD A;  2F1G A;  1SNK A;  2P86 A;  1PBH A;  5CVM A;  2H7J A;  1YT7 A;  6PAD A;  1KHP A;  2DC6 A;  3H89 A;  4Q8H A;  2HXZ A;  3S3Q A;  1HUC B;  2G7Y A;  3K24 A;  4X6J A;  1NL6 A;  4P6E A;  3N3K A;  2E00 A;  1Y4H A;  2AYN A;  1AU2 A;  1CTE A;  1STF E;  1F29 A;  2AVW A;  3MOR A;  4K7C A;  1ZIV A;  4DMX A;  3PBH A;  3KW9 A;  3OF8 A;  5FPW A;  3MHS A;  4QBB A;  1GCB A;  4QRG A;  2ACT A;  2E01 A;  4CDC B;  1EWL A;  4BPV A;  4Q8G A;  5CHV A;  3CH2 X;  3WXF A;  2C0Y A;  3O1G A;  3IHP A;  3PW3 A;  5EF4 A;  1DEU A;  3E1Z B;  3RVW A;  3HHA A;  3BCN A;  4YYS A;  2P7U A;  4DMY A;  1CV8 A;  1ZCM A;  4WA6 A;  2PRE A;  3K9M A;  3D6S A;  2ARY A;  4X6H A;  2FUD A;  5J94 A;  4QRV A;  2DZZ A;  4MZS A;  2GFO A;  4CDD B;  2YJ8 A;  3DF0 A;  1CSB B;  2FYE A; 
#chains in the Genus database with same CATH topology
 1NB3 A;  3MTV A;  3K8U A;  4PP1 A;  5JA7 A;  1M6D A;  2P0R A;  3H6S A;  2JTC A;  1CQD A;  1EWO A;  1CB5 A;  1ME4 A;  2BDZ A;  2AIM A;  3WXE A;  2FE8 A;  2BTW B;  3I3T A;  3OIS A;  1MEM A;  4PP2 E;  4BOS A;  4BQV A;  4AXM A;  1PE6 A;  3O65 A;  2YJ9 A;  2G8J A;  2WBF X;  3LXS A;  4BOP A;  3P5V A;  1TLO A;  1U9W A;  1MIR A;  1CS8 A;  4FIP A;  1YZB A;  2DZY A;  3C9E A;  4I07 A;  4I05 A;  3W30 A;  2IPP B;  1CVZ A;  3HWN A;  3PSE A;  4KLB A;  1TL9 A;  3IV2 A;  1AU0 A;  2DJG B;  3LFY A;  4QRX A;  5JH3 A;  2J7Q A;  1Y08 A;  3I06 A;  1NLJ A;  4FK5 A;  3OVX A;  1F2C A;  4PAD A;  5JZE A;  4N4Z A;  1QOL A;  1U9Q X;  2FRQ A;  3CH3 X;  2AU1 A;  5E6J A;  4IP3 A;  2YJB A;  2PNS A;  3S3R A;  2FO5 A;  3GCB A;  5F02 A;  5PAD A;  5A24 A;  1ATK A;  3MP2 A;  2B1M A;  4MSX A;  2AUZ A;  2FT2 A;  4D8B A;  3BBA A;  2FRA A;  1ICF A;  2HD5 A;  4OEL A;  2AS8 A;  3U8E A;  2NQA A;  3C0R A;  1AYU A;  3IOQ A;  2XU1 A;  3CBJ A;  2JQF R;  3IEJ A;  1F2A A;  3KSE A;  3PHX A;  2DOS A;  3NHE A;  3KKU A;  3HHI A;  1PAD A;  4GUA A;  1EWM A;  4N79 A;  1QXP A;  3HD3 A;  3RVV A;  2UZJ A;  3MHH A;  1YK7 A;  2E03 A;  1AYW A;  1GMY A;  1K3B B;  4RF0 A;  1QMY A;  3PRM A;  4OW0 A;  1U5I A;  2G8E A;  2NQD B;  3F5V A;  3MTN A;  3PRP A;  3ZUA A;  1S4V A;  2FTD A;  2HH5 A;  2R9N A;  1PIP A;  3O0U A;  1YVB A;  1QDQ A;  1THE A;  4PT5 A;  1XKG A;  1PCI A;  2XU3 A;  1U9V A;  1CJL A;  2R9M A;  3KFQ A;  2AGA A;  3QJ3 A;  2R6N A;  4D8E A;  2HWK A;  3BPF A;  3F75 A;  2HHN A;  3N3G A;  4FJC A;  1AU4 A;  3OF9 A;  3BWK A;  3V6E A;  2Y5B A;  1FH0 A;  1VSN A;  4A5U A;  3KWB X;  1BGO A;  1Q6K A;  8PCH A;  3M99 A;  1PPN A;  3PDF A;  3BC3 A;  4W4U A;  4BOZ A;  1EF7 A;  4RY2 A;  4CDE B;  4YYV A;  1PPP A;  2G6D A;  2F7D A;  4BS5 A;  3QT4 A;  1AIM A;  2BDL A;  4XR7 A;  4X6I A;  1ME3 A;  4W5B A;  4AXL A;  2DCC A;  3OQC A;  4RNA A;  1NQC A;  1PPD A;  3OVZ A;  3TRK A;  1AEC A;  3N4C A;  1ITO A;  3V6C A;  3PT2 A;  4REZ A;  4PI3 A;  3WXG A;  1NB5 A;  5EZS A;  2DC7 A;  3KWZ A;  3IMA A;  4N8W A;  4OVZ A;  9PAP A;  1MHW A;  2AUX A;  2R9C A;  2R9F A;  4YVA A;  2DCB A;  2OZ2 A;  1AU3 A;  2OUL A;  2VHS A;  2YJC A;  1A6R A;  4MI7 A;  3QSD A;  1BQI A;  4XZX A;  3PNR A;  3ZNH A;  1PPO A;  1YAL A;  4BSQ A;  4D8I A;  1GLO A;  2PBH A;  3ERV A;  4ZTB A;  1JQP A;  4ZUX U;  4YYU A;  3B21 A;  3W31 A;  3TNX A;  2B1N A;  4HXD B;  4RKX A;  4XUI A;  1YK8 A;  2DC9 A;  4YYQ A;  3IUT A;  4QH6 A;  1MS6 A;  3P5X A;  3H8C A;  4CZW A;  2OP3 A;  2YJ2 A;  4CDF B;  2BU3 A;  4P16 A;  3CBK A;  2O6X A;  4BOU A;  1BP4 A;  3BOW A;  1KXR A;  2GHU A;  2DCA A;  2JRI A;  4YYW A;  3AI8 A;  1O0E A;  1X9Y A;  1PVJ A;  1NPZ A;  4BOQ A;  3KX1 A;  4YYR A;  4HWY A;  1PXV A;  1VJV A;  3H7D A;  4I04 A;  1KHQ A;  1GEC E;  2NQG A;  1BY8 A;  3USV A;  1U9X A;  1TU6 A;  3RVX A;  3TMP A;  2BTW A;  3BPM A;  5CVN B;  5CHT A;  1MEG A;  4MZO A;  4IUM A;  1KFU L;  2FQ9 A;  1AYV A;  1CPJ A;  2NQI A;  3PHW A;  1SP4 B;  1MDW A;  2AYO A;  4M0W A;  2ATO A;  1EWP A;  2DJF B;  5KO3 A;  3P5U A;  2DC8 A;  7PCK A;  2JQG R;  1DF0 A;  2E02 A;  4BS6 A;  2XU4 A;  2Y6E A;  3P5W A;  3MJ5 A;  4G54 A;  2R9O A;  3H8B A;  2CB5 A;  4R3D A;  2Z84 A;  3B79 A;  3BY4 A;  2CIO A;  4W5C A;  2IBI A;  2VHF A;  1F2B A;  1POP A;  5EGW A;  5CVO B;  4MM3 B;  2XU5 A;  4RF1 A;  1KFX L;  4OEM A;  4YV8 A;  5K16 A;  1IWD A;  4P6G A;  2DCD A;  2PAD A;  2F1G A;  1SNK A;  2P86 A;  1PBH A;  5CVM A;  2H7J A;  3PHU A;  1YT7 A;  6PAD A;  1KHP A;  1UKF A;  2DC6 A;  3H89 A;  4Q8H A;  2HXZ A;  3S3Q A;  1HUC B;  2G7Y A;  3K24 A;  4X6J A;  1NL6 A;  4P6E A;  3N3K A;  2E00 A;  1Y4H A;  2AYN A;  2J7Q C;  4OVZ B;  1AU2 A;  1CTE A;  1STF E;  1F29 A;  2AVW A;  3MOR A;  4K7C A;  1ZIV A;  4DMX A;  3PBH A;  3KW9 A;  3E9S A;  3OF8 A;  5FPW A;  3MHS A;  4QBB A;  1GCB A;  4QRG A;  2ACT A;  2E01 A;  4CDC B;  1EWL A;  4BPV A;  4Q8G A;  1DKI A;  5CHV A;  3CH2 X;  3WXF A;  2C0Y A;  3RNV A;  3O1G A;  3IHP A;  3PW3 A;  5EF4 A;  1DEU A;  3E1Z B;  4WUR A;  3RVW A;  3HHA A;  3BCN A;  4YYS A;  2P7U A;  4DMY A;  1CV8 A;  1ZCM A;  5EZQ A;  4WA6 A;  2PRE A;  3IFU A;  3K9M A;  3D6S A;  2ARY A;  3BB7 A;  4X6H A;  2FUD A;  5J94 A;  4QRV A;  2DZZ A;  4MZS A;  2GFO A;  4CDD B;  2YJ8 A;  3DF0 A;  1CSB B;  2FYE A; 
#chains in the Genus database with same CATH homology
 1NB3 A;  3K8U A;  4PP1 A;  5JA7 A;  1M6D A;  2P0R A;  3H6S A;  1CQD A;  1EWO A;  1CB5 A;  1ME4 A;  2BDZ A;  2AIM A;  3WXE A;  3I3T A;  3OIS A;  1MEM A;  4PP2 E;  4BQV A;  4AXM A;  1PE6 A;  2YJ9 A;  2G8J A;  2WBF X;  3LXS A;  3P5V A;  1TLO A;  1U9W A;  1MIR A;  1CS8 A;  4FIP A;  2DZY A;  3C9E A;  4I07 A;  4I05 A;  2IPP B;  1CVZ A;  3HWN A;  2VFC A;  4KLB A;  1TL9 A;  3IV2 A;  1AU0 A;  2DJG B;  3LFY A;  4QRX A;  5JH3 A;  1Y08 A;  3I06 A;  2BSZ A;  1NLJ A;  4FK5 A;  3OVX A;  1F2C A;  4PAD A;  4N4Z A;  1QOL A;  1U9Q X;  2FRQ A;  3CH3 X;  2AU1 A;  2YJB A;  2PNS A;  3S3R A;  4BGF A;  2FO5 A;  3GCB A;  5F02 A;  5PAD A;  5A24 A;  1ATK A;  2B1M A;  3D9W A;  4MSX A;  2AUZ A;  2FT2 A;  2FRA A;  1ICF A;  2HD5 A;  4OEL A;  2AS8 A;  3U8E A;  2NQA A;  1AYU A;  3IOQ A;  2XU1 A;  3CBJ A;  2JQF R;  3IEJ A;  1F2A A;  3KSE A;  3NHE A;  3KKU A;  3HHI A;  1PAD A;  1EWM A;  4N79 A;  1QXP A;  3HD3 A;  3RVV A;  3MHH A;  1YK7 A;  2E03 A;  1AYW A;  1GMY A;  1K3B B;  1QMY A;  1U5I A;  2G8E A;  2NQD B;  3F5V A;  3MTN A;  3ZUA A;  1S4V A;  2FTD A;  2HH5 A;  2R9N A;  1PIP A;  3O0U A;  1YVB A;  1QDQ A;  1THE A;  1XKG A;  1PCI A;  2XU3 A;  1U9V A;  1CJL A;  2R9M A;  3KFQ A;  3QJ3 A;  2R6N A;  3BPF A;  3F75 A;  2HHN A;  3N3G A;  4FJC A;  1AU4 A;  3OF9 A;  3BWK A;  3V6E A;  2Y5B A;  1FH0 A;  1VSN A;  3KWB X;  1BGO A;  1Q6K A;  8PCH A;  3M99 A;  1PPN A;  3PDF A;  3BC3 A;  4W4U A;  1EF7 A;  4RY2 A;  4CDE B;  4YYV A;  1PPP A;  2G6D A;  2F7D A;  4BS5 A;  3QT4 A;  1AIM A;  2BDL A;  4XR7 A;  4X6I A;  1ME3 A;  4W5B A;  4AXL A;  2DCC A;  1NQC A;  1W6F A;  1W5R A;  1PPD A;  3OVZ A;  1AEC A;  3N4C A;  1W4T A;  1ITO A;  2VFB A;  3V6C A;  3WXG A;  4PI3 A;  1NB5 A;  2DC7 A;  3KWZ A;  3IMA A;  4N8W A;  9PAP A;  1MHW A;  2AUX A;  2R9C A;  2R9F A;  4YVA A;  2DCB A;  2OZ2 A;  1AU3 A;  2OUL A;  2VHS A;  2YJC A;  1A6R A;  3QSD A;  1BQI A;  3PNR A;  1PPO A;  1YAL A;  4BSQ A;  1GLO A;  2PBH A;  3ERV A;  4NV8 A;  1JQP A;  4ZUX U;  4YYU A;  3TNX A;  2B1N A;  4XUI A;  1YK8 A;  2DC9 A;  4YYQ A;  3IUT A;  4QH6 A;  1MS6 A;  3P5X A;  3H8C A;  4CZW A;  2OP3 A;  2YJ2 A;  4CDF B;  3CBK A;  2O6X A;  1BP4 A;  3BOW A;  1KXR A;  2GHU A;  2DCA A;  4YYW A;  3AI8 A;  1O0E A;  1X9Y A;  1NPZ A;  3KX1 A;  4YYR A;  4HWY A;  1PXV A;  1VJV A;  3H7D A;  4I04 A;  1KHQ A;  1GEC E;  2NQG A;  1BY8 A;  3USV A;  1U9X A;  1TU6 A;  3RVX A;  3BPM A;  5CVN B;  5CHT A;  1MEG A;  4MZO A;  1KFU L;  2FQ9 A;  1AYV A;  1CPJ A;  2NQI A;  1SP4 B;  1MDW A;  2AYO A;  2ATO A;  1EWP A;  2DJF B;  3P5U A;  2DC8 A;  7PCK A;  2JQG R;  1DF0 A;  2E02 A;  4BS6 A;  2XU4 A;  2Y6E A;  3LTW A;  4C5P A;  3P5W A;  4G54 A;  2R9O A;  3H8B A;  2CB5 A;  3B79 A;  4B55 A;  2CIO A;  4W5C A;  2IBI A;  2VHF A;  1F2B A;  1POP A;  5EGW A;  5CVO B;  2XU5 A;  1KFX L;  4OEM A;  4YV8 A;  5K16 A;  1IWD A;  4P6G A;  2DCD A;  2PAD A;  2F1G A;  1SNK A;  2P86 A;  1PBH A;  5CVM A;  2H7J A;  1GX3 A;  1YT7 A;  6PAD A;  1KHP A;  2DC6 A;  3H89 A;  4Q8H A;  2HXZ A;  3S3Q A;  1HUC B;  2G7Y A;  4NV7 A;  3K24 A;  4X6J A;  1NL6 A;  4P6E A;  3N3K A;  2E00 A;  1Y4H A;  2AYN A;  1E2T A;  1AU2 A;  1CTE A;  1STF E;  1F29 A;  2AVW A;  3MOR A;  4K7C A;  1ZIV A;  4DMX A;  3PBH A;  3KW9 A;  3OF8 A;  5FPW A;  3MHS A;  4QBB A;  1GCB A;  4QRG A;  2ACT A;  2E01 A;  4CDC B;  1EWL A;  4BPV A;  4Q8G A;  5CHV A;  3CH2 X;  3WXF A;  2C0Y A;  3O1G A;  3IHP A;  4GUZ A;  3PW3 A;  5EF4 A;  1DEU A;  3E1Z B;  3RVW A;  3HHA A;  3BCN A;  4YYS A;  2P7U A;  4DMY A;  1CV8 A;  1ZCM A;  4WA6 A;  2PRE A;  3K9M A;  3D6S A;  2ARY A;  4X6H A;  2FUD A;  5J94 A;  4QRV A;  2DZZ A;  4MZS A;  2GFO A;  4CDD B;  2YJ8 A;  3DF0 A;  1CSB B;  2FYE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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