1MEMA

Crystal structure of cathepsin k complexed with a potent vinyl sulfone inhibitor
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
215
structure length
215
Chain Sequence
APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of human cathepsin K complexed with a potent inhibitor.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Cathepsin K
total genus 56
structure length 215
sequence length 215
ec nomenclature ec 3.4.22.38: Cathepsin K.
pdb deposition date 1997-01-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1memA00
3V6CA 4X6IA 2R9OA 2NQDB 4MZSA 2YJ2A 2CB5A 4FJCA 3I3TA 2AS8A 2NQGA 1SP4B 4PI3A 4P6GA 4BS5A 1ZIVA 1XKGA 1U9VA 2ARYA 2PNSA 4Q8HA 3CH3X 3LXSA 4MSXA 1CVZA 1KFUL 2PREA 4CDEB 1EWLA 2FYEA 3P5WA 1GECE 2DJFB 4PADA 2CIOA 3BC3A 2XU4A 3P5XA 3RVXA 2VHFA 2VHSA 4PP1A 1PXVA 3MHSA 2GHUA 2O6XA 1CV8A 5FPWA 3IMAA 3P5UA 3DF0A 3ZUAA 1DF0A 2Y5BA 1THEA 1U9WA 2HHNA 1AU0A 1SNKA 2XU3A 1AYVA 2FQ9A 3HWNA 1M6DA 5F02A 1EWOA 3U8EA 4YYWA 2C0YA 4CDFB 3MORA 3KW9A 3BCNA 2NQIA 4CDDB 2NQAA 1CS8A 1PPPA 2YJBA 1F29A 4I04A 3HD3A 1DEUA 1CQDA 4DMYA 1CJLA 1NQCA 1KHPA 5CHTA 3IUTA 1ATKA 1YVBA 4XUIA 2AYNA 2FRQA 4AXMA 1YALA 2R9MA 4YV8A 3ERVA 4WA6A 3H8BA 4Q8GA 1KFXL 2AIMA 3BWKA 3H6SA 8PCHA 1IWDA 3GCBA 3KX1A 2F7DA 3M99A 1YK8A 3IHPA 3OF9A 3QJ3A 3K9MA 4I07A 3PDFA 1MHWA 2FT2A 2OP3A 1BP4A 3HHAA 3PBHA 1AECA 1NB3A 2ACTA 2B1NA 2YJ9A 1YK7A 1PADA 1QMYA 3H7DA 1PPDA 4QRVA 1BQIA 1GCBA 1CB5A 3HHIA 2DC6A 5CVMA 1PPOA 2DCAA 1PCIA 3OF8A 1MEMA 2G8EA 4N8WA 1AU2A 2B1MA 1VSNA 2P86A 1ITOA 1BY8A 3BOWA 9PAPA 1GMYA 1ME4A 2G8JA 1NPZA 5JA7A 3IEJA 2DC9A 2FRAA 2FO5A 1MDWA 2PBHA 4CDCB 1EF7A 2F1GA 5CVNB 3WXEA 4OELA 1NB5A 3IOQA 6PADA 2DCCA 2JQGR 1JQPA 1AYUA 1NLJA 1EWPA 3S3RA 1GLOA 3KFQA 7PCKA 1ZCMA 2P0RA 4AXLA 4QRXA 1MIRA 1U5IA 3O1GA 1NL6A 1AIMA 1MS6A 4P6EA 1S4VA 2G7YA 2AU1A 2DCDA 2E02A 3S3QA 3C9EA 3NHEA 2DCBA 3KWBX 5A24A 4QRGA 1POPA 2AUXA 2R9CA 2ATOA 1TL9A 1K3BB 1F2BA 2HD5A 3V6EA 4PP2E 4QH6A 4K7CA 5K16A 4I05A 5EGWA 1QDQA 1VJVA 1A6RA 4HWYA 1PBHA 1F2AA 3N4CA 3CH2X 2YJ8A 3H8CA 2GFOA 3KSEA 3MTNA 3RVWA 2WBFX 4BSQA 4W4UA 3N3GA 3TNXA 3QT4A 1U9QX 1AYWA 1ME3A 1AU4A 1AU3A 4YVAA 1Y4HA 2PADA 1X9YA 2R9FA 3BPMA 3D6SA 3LFYA 1KHQA 4N4ZA 4QBBA 2E01A 3E1ZB 2FTDA 1Q6KA 3USVA 2E00A 3OVXA 1PIPA 3H89A 3KKUA 1QXPA 4FIPA 2OZ2A 1Y08A 1QOLA 4YYRA 1PPNA 3MHHA 1TLOA 3B79A 3F5VA 2XU5A 3K8UA 1CPJA 1O0EA 1PE6A 4BQVA 2IBIA 4W5BA 2DC8A 3O0UA 2BDZA 4MZOA 2H7JA 1F2CA 2YJCA 4X6HA 1YT7A 3PNRA 3KWZA 2G6DA 4YYQA 2E03A 1CSBB 5CVOB 2R9NA 2OULA 2DJGB 3P5VA 2XU1A 2DZYA 2DC7A 3I06A 2FUDA 3CBJA 4YYVA 2HH5A 2BDLA 4W5CA 1TU6A 4OEMA 2R6NA 1BGOA 1ICFA 1HUCB 4G54A 5PADA 3QSDA 1FH0A 3RVVA 4N79A 4YYUA 4RY2A 4XR7A 4ZUXU 2AUZA 3AI8A 4DMXA 1MEGA 2JQFR 3CBKA 5JH3A 2HXZA 3PW3A 4BS6A 5J94A 3N3KA 2IPPB 4BPVA 3IV2A 1EWMA 3WXFA 1STFE 4X6JA 3OISA 2P7UA 3F75A 4YYSA 4KLBA 2AVWA 4FK5A 2Y6EA 2AYOA 1CTEA 1KXRA 5EF4A 1U9XA 5CHVA 2DZZA 3OVZA 4CZWA 3BPFA 3K24A 3WXGA
chains in the Genus database with same CATH superfamily
3V6CA 4X6IA 4BOZA 2R9OA 2NQDB 4BOQA 3PHXA 4MZSA 2YJ2A 5EZSA 2CB5A 4FJCA 3I3TA 2AS8A 2NQGA 1SP4B 4PI3A 4P6GA 4BS5A 1ZIVA 4RKXA 3PHUA 1XKGA 1U9VA 2ARYA 2PNSA 4Q8HA 3CH3X 3LXSA 4MSXA 1CVZA 1KFUL 2PREA 4RF1A 4CDEB 1EWLA 2BU3A 2FYEA 3P5WA 3PSEA 1GECE 2DJFB 4PADA 2CIOA 3BC3A 2XU4A 3P5XA 3PHWA 3RVXA 2VHFA 2VHSA 1PXVA 3MHSA 4PP1A 2GHUA 2O6XA 1CV8A 3E9SA 3IMAA 5FPWA 3P5UA 4OVZA 3DF0A 3PRPA 3ZUAA 1DF0A 2Y5BA 1THEA 1U9WA 2HHNA 1AU0A 1SNKA 4BOUA 3BB7A 2XU3A 1AYVA 2FQ9A 3HWNA 1M6DA 5F02A 1EWOA 3U8EA 3ZNHA 4YYWA 2C0YA 4CDFB 3MORA 3KW9A 3BCNA 2NQIA 4IUMA 4CDDB 2NQAA 1CS8A 1PPPA 2YJBA 1F29A 4I04A 4BOPA 4RNAA 3C0RA 3HD3A 1DEUA 1CQDA 4DMYA 1CJLA 1NQCA 1KHPA 5CHTA 3IUTA 1ATKA 1YVBA 4XUIA 2AYNA 2FRQA 4AXMA 1YALA 2R9MA 4YV8A 3ERVA 4WA6A 3H8BA 4Q8GA 1KFXL 2AIMA 3BWKA 4OW0A 3H6SA 8PCHA 1IWDA 3GCBA 4D8EA 3KX1A 2F7DA 3M99A 4IP3A 1YK8A 3IHPA 3OF9A 3QJ3A 2JTCA 3K9MA 4I07A 3PDFA 1MHWA 2FT2A 2OP3A 1BP4A 3HHAA 3PBHA 1AECA 1NB3A 2ACTA 2B1NA 2YJ9A 1YK7A 1PADA 1QMYA 4HXDB 3H7DA 1PPDA 4ZTBA 4QRVA 1BQIA 1GCBA 1CB5A 3W31A 3HHIA 2DC6A 5CVMA 1PPOA 2DCAA 1PCIA 3OF8A 3BBAA 4MM3B 4P16A 1MEMA 2G8EA 4N8WA 1AU2A 3B21A 2B1MA 2UZJA 1VSNA 2P86A 1ITOA 1BY8A 3BOWA 9PAPA 3RNVA 1DKIA 4M0WA 1GMYA 1ME4A 4RF0A 2G8JA 1NPZA 4R3DA 5JA7A 3IEJA 2DC9A 2FRAA 2FO5A 1MDWA 2PBHA 4CDCB 4D8BA 1EF7A 2F1GA 5CVNB 3WXEA 4OELA 1NB5A 3IOQA 6PADA 4OVZB 3MP2A 1YZBA 2DCCA 2JQGR 1JQPA 1AYUA 1NLJA 1EWPA 3S3RA 1GLOA 3KFQA 4XZXA 7PCKA 1ZCMA 2P0RA 3MJ5A 4AXLA 4QRXA 1MIRA 1U5IA 3O1GA 1NL6A 1AIMA 1MS6A 4P6EA 1S4VA 4GUAA 2G7YA 2AU1A 2JRIA 2DCDA 2E02A 3S3QA 3C9EA 3NHEA 2FE8A 2DCBA 3KWBX 5JZEA 5A24A 4QRGA 1POPA 2AUXA 2R9CA 2ATOA 1TL9A 1K3BB 1PVJA 1F2BA 2HD5A 3V6EA 4PP2E 4QH6A 4K7CA 5K16A 4I05A 5EGWA 1QDQA 1VJVA 1A6RA 3N4CA 1PBHA 1F2AA 4HWYA 3CH2X 4REZA 2YJ8A 3H8CA 2GFOA 3KSEA 3MTNA 3RVWA 2WBFX 4BSQA 4W4UA 3N3GA 3TNXA 3QT4A 1U9QX 1AYWA 1ME3A 2BTWA 1AU4A 1AU3A 4YVAA 1Y4HA 2PADA 1X9YA 2R9FA 3BPMA 3D6SA 2AGAA 3LFYA 1KHQA 4N4ZA 4QBBA 2BTWB 2E01A 3E1ZB 2FTDA 1Q6KA 3USVA 2E00A 3OVXA 1PIPA 5E6JA 3H89A 3KKUA 1QXPA 4FIPA 2OZ2A 1Y08A 1QOLA 4YYRA 1PPNA 3MHHA 1TLOA 3B79A 3F5VA 2XU5A 3K8UA 1CPJA 5EZQA 5KO3A 1O0EA 1PE6A 4A5UA 4BQVA 2IBIA 4W5BA 2DC8A 4BOSA 4D8IA 3OQCA 3O0UA 2BDZA 4MZOA 3IFUA 2H7JA 3O65A 1F2CA 2YJCA 4X6HA 1YT7A 3PNRA 3KWZA 2G6DA 4YYQA 2E03A 1CSBB 5CVOB 2R9NA 2J7QA 2Z84A 2OULA 2DJGB 3P5VA 1UKFA 2XU1A 2DZYA 2J7QC 2DC7A 3I06A 4WURA 2FUDA 3CBJA 3TMPA 4YYVA 2HH5A 2BDLA 4W5CA 2HWKA 1TU6A 4OEMA 3TRKA 2R6NA 1BGOA 1ICFA 1HUCB 4MI7A 4G54A 5PADA 1FH0A 3QSDA 3RVVA 4N79A 4YYUA 4RY2A 4XR7A 4ZUXU 2AUZA 3AI8A 4DMXA 1MEGA 2JQFR 3CBKA 5JH3A 2HXZA 3PW3A 4BS6A 5J94A 3N3KA 3PT2A 3MTVA 2IPPB 4BPVA 3IV2A 1EWMA 3WXFA 1STFE 4X6JA 3OISA 2P7UA 3F75A 4YYSA 4KLBA 2AVWA 4FK5A 2Y6EA 2AYOA 2DOSA 1CTEA 1KXRA 5EF4A 1U9XA 5CHVA 2DZZA 3BY4A 4PT5A 3PRMA 3OVZA 4CZWA 3BPFA 3K24A 3W30A 3WXGA
chains in the Genus database with same CATH topology
3V6CA 4X6IA 2R9OA 2NQDB 2VFBA 4MZSA 2YJ2A 2CB5A 4FJCA 3I3TA 2AS8A 2NQGA 1SP4B 4PI3A 4P6GA 4BS5A 1ZIVA 4B55A 1XKGA 1U9VA 2ARYA 2PNSA 4Q8HA 3CH3X 3LXSA 4MSXA 1CVZA 1KFUL 2PREA 4CDEB 1EWLA 2FYEA 3P5WA 1GECE 2DJFB 4PADA 2CIOA 3BC3A 2XU4A 3P5XA 3RVXA 2VHFA 2VHSA 1PXVA 3MHSA 4PP1A 2GHUA 2O6XA 1CV8A 5FPWA 3IMAA 3P5UA 3DF0A 3ZUAA 1DF0A 2Y5BA 1THEA 1U9WA 2HHNA 1AU0A 1SNKA 2XU3A 1AYVA 2FQ9A 3HWNA 1M6DA 5F02A 1EWOA 3U8EA 4YYWA 2C0YA 4CDFB 3MORA 3KW9A 3BCNA 2NQIA 4CDDB 2NQAA 1CS8A 1PPPA 2YJBA 1F29A 4I04A 1E2TA 3HD3A 1DEUA 1CQDA 4DMYA 1CJLA 1NQCA 1KHPA 5CHTA 3IUTA 1ATKA 1YVBA 4XUIA 2AYNA 2FRQA 4AXMA 1YALA 2R9MA 4YV8A 3ERVA 4WA6A 3H8BA 4Q8GA 1KFXL 2AIMA 3BWKA 3H6SA 8PCHA 1IWDA 3GCBA 3KX1A 2F7DA 3M99A 1YK8A 3IHPA 3OF9A 3QJ3A 3K9MA 4I07A 3PDFA 4C5PA 1MHWA 2FT2A 2OP3A 1BP4A 3HHAA 3PBHA 1AECA 1NB3A 2ACTA 2B1NA 2YJ9A 1YK7A 1PADA 1QMYA 3H7DA 1PPDA 4QRVA 1BQIA 1GCBA 1CB5A 3HHIA 2DC6A 5CVMA 1PPOA 2DCAA 1PCIA 3OF8A 1MEMA 2G8EA 4N8WA 1AU2A 2B1MA 1GX3A 1VSNA 2P86A 1ITOA 1BY8A 3BOWA 9PAPA 1GMYA 1ME4A 2G8JA 1NPZA 5JA7A 3IEJA 2DC9A 2FRAA 2FO5A 1MDWA 2PBHA 4CDCB 1EF7A 2F1GA 5CVNB 3WXEA 4OELA 1NB5A 3IOQA 6PADA 2DCCA 2JQGR 1JQPA 1AYUA 1NLJA 1EWPA 3S3RA 1GLOA 3KFQA 7PCKA 1ZCMA 2P0RA 4AXLA 4QRXA 1MIRA 1U5IA 3O1GA 1NL6A 1AIMA 1MS6A 4P6EA 1S4VA 2G7YA 2AU1A 2DCDA 2E02A 3S3QA 3C9EA 3NHEA 1W6FA 4GUZA 2DCBA 3KWBX 5A24A 4QRGA 1POPA 2AUXA 4NV8A 2R9CA 2ATOA 1TL9A 1K3BB 1F2BA 2HD5A 3V6EA 4PP2E 4QH6A 4K7CA 5K16A 4I05A 5EGWA 1QDQA 1VJVA 1A6RA 4HWYA 1PBHA 1F2AA 3N4CA 3CH2X 2YJ8A 3H8CA 2GFOA 3KSEA 3MTNA 3RVWA 2WBFX 3D9WA 4BSQA 4W4UA 3N3GA 3TNXA 3QT4A 1U9QX 1AYWA 1ME3A 1AU4A 1AU3A 4YVAA 1Y4HA 2PADA 1X9YA 2R9FA 3BPMA 3D6SA 3LFYA 1KHQA 4N4ZA 4QBBA 2E01A 3E1ZB 2FTDA 1Q6KA 3USVA 2E00A 3OVXA 1PIPA 3H89A 3KKUA 1QXPA 4FIPA 2OZ2A 1Y08A 1QOLA 4YYRA 1PPNA 3MHHA 1TLOA 3B79A 3F5VA 2XU5A 3K8UA 1CPJA 1O0EA 1PE6A 4BQVA 1W5RA 2IBIA 4W5BA 2DC8A 3O0UA 2BDZA 4MZOA 2H7JA 1F2CA 2YJCA 4X6HA 1YT7A 3PNRA 3KWZA 2G6DA 4YYQA 2E03A 1CSBB 1W4TA 5CVOB 2R9NA 2BSZA 2OULA 2DJGB 3P5VA 2XU1A 2DZYA 2DC7A 3I06A 2FUDA 3CBJA 4YYVA 2HH5A 2BDLA 4W5CA 1TU6A 4OEMA 2R6NA 1BGOA 1ICFA 1HUCB 4G54A 5PADA 3QSDA 1FH0A 3RVVA 4N79A 4YYUA 4BGFA 4RY2A 4XR7A 4ZUXU 2AUZA 3AI8A 4DMXA 1MEGA 2JQFR 4NV7A 3CBKA 5JH3A 2HXZA 3PW3A 4BS6A 5J94A 2VFCA 3N3KA 2IPPB 4BPVA 3IV2A 1EWMA 3WXFA 1STFE 4X6JA 3OISA 2P7UA 3F75A 4YYSA 4KLBA 2AVWA 4FK5A 2Y6EA 2AYOA 1CTEA 1KXRA 5EF4A 1U9XA 5CHVA 2DZZA 3LTWA 3OVZA 4CZWA 3BPFA 3K24A 3WXGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3V6C A;  4X6I A;  2R9O A;  2NQD B;  4MZS A;  2YJ2 A;  2CB5 A;  4FJC A;  3I3T A;  2AS8 A;  2NQG A;  1SP4 B;  4PI3 A;  4P6G A;  4BS5 A;  1ZIV A;  1XKG A;  1U9V A;  2ARY A;  2PNS A;  4Q8H A;  3CH3 X;  3LXS A;  4MSX A;  1CVZ A;  1KFU L;  2PRE A;  4CDE B;  1EWL A;  2FYE A;  3P5W A;  1GEC E;  2DJF B;  4PAD A;  2CIO A;  3BC3 A;  2XU4 A;  3P5X A;  3RVX A;  2VHF A;  2VHS A;  4PP1 A;  1PXV A;  3MHS A;  2GHU A;  2O6X A;  1CV8 A;  5FPW A;  3IMA A;  3P5U A;  3DF0 A;  3ZUA A;  1DF0 A;  2Y5B A;  1THE A;  1U9W A;  2HHN A;  1AU0 A;  1SNK A;  2XU3 A;  1AYV A;  2FQ9 A;  3HWN A;  1M6D A;  5F02 A;  1EWO A;  3U8E A;  4YYW A;  2C0Y A;  4CDF B;  3MOR A;  3KW9 A;  3BCN A;  2NQI A;  4CDD B;  2NQA A;  1CS8 A;  1PPP A;  2YJB A;  1F29 A;  4I04 A;  3HD3 A;  1DEU A;  1CQD A;  4DMY A;  1CJL A;  1NQC A;  1KHP A;  5CHT A;  3IUT A;  1ATK A;  1YVB A;  4XUI A;  2AYN A;  2FRQ A;  4AXM A;  1YAL A;  2R9M A;  4YV8 A;  3ERV A;  4WA6 A;  3H8B A;  4Q8G A;  1KFX L;  2AIM A;  3BWK A;  3H6S A;  8PCH A;  1IWD A;  3GCB A;  3KX1 A;  2F7D A;  3M99 A;  1YK8 A;  3IHP A;  3OF9 A;  3QJ3 A;  3K9M A;  4I07 A;  3PDF A;  1MHW A;  2FT2 A;  2OP3 A;  1BP4 A;  3HHA A;  3PBH A;  1AEC A;  1NB3 A;  2ACT A;  2B1N A;  2YJ9 A;  1YK7 A;  1PAD A;  1QMY A;  3H7D A;  1PPD A;  4QRV A;  1BQI A;  1GCB A;  1CB5 A;  3HHI A;  2DC6 A;  5CVM A;  1PPO A;  2DCA A;  1PCI A;  3OF8 A;  1MEM A;  2G8E A;  4N8W A;  1AU2 A;  2B1M A;  1VSN A;  2P86 A;  1ITO A;  1BY8 A;  3BOW A;  9PAP A;  1GMY A;  1ME4 A;  2G8J A;  1NPZ A;  5JA7 A;  3IEJ A;  2DC9 A;  2FRA A;  2FO5 A;  1MDW A;  2PBH A;  4CDC B;  1EF7 A;  2F1G A;  5CVN B;  3WXE A;  4OEL A;  1NB5 A;  3IOQ A;  6PAD A;  2DCC A;  2JQG R;  1JQP A;  1AYU A;  1NLJ A;  1EWP A;  3S3R A;  1GLO A;  3KFQ A;  7PCK A;  1ZCM A;  2P0R A;  4AXL A;  4QRX A;  1MIR A;  1U5I A;  3O1G A;  1NL6 A;  1AIM A;  1MS6 A;  4P6E A;  1S4V A;  2G7Y A;  2AU1 A;  2DCD A;  2E02 A;  3S3Q A;  3C9E A;  3NHE A;  2DCB A;  3KWB X;  5A24 A;  4QRG A;  1POP A;  2AUX A;  2R9C A;  2ATO A;  1TL9 A;  1K3B B;  1F2B A;  2HD5 A;  3V6E A;  4PP2 E;  4QH6 A;  4K7C A;  5K16 A;  4I05 A;  5EGW A;  1QDQ A;  1VJV A;  1A6R A;  4HWY A;  1PBH A;  1F2A A;  3N4C A;  3CH2 X;  2YJ8 A;  3H8C A;  2GFO A;  3KSE A;  3MTN A;  3RVW A;  2WBF X;  4BSQ A;  4W4U A;  3N3G A;  3TNX A;  3QT4 A;  1U9Q X;  1AYW A;  1ME3 A;  1AU4 A;  1AU3 A;  4YVA A;  1Y4H A;  2PAD A;  1X9Y A;  2R9F A;  3BPM A;  3D6S A;  3LFY A;  1KHQ A;  4N4Z A;  4QBB A;  2E01 A;  3E1Z B;  2FTD A;  1Q6K A;  3USV A;  2E00 A;  3OVX A;  1PIP A;  3H89 A;  3KKU A;  1QXP A;  4FIP A;  2OZ2 A;  1Y08 A;  1QOL A;  4YYR A;  1PPN A;  3MHH A;  1TLO A;  3B79 A;  3F5V A;  2XU5 A;  3K8U A;  1CPJ A;  1O0E A;  1PE6 A;  4BQV A;  2IBI A;  4W5B A;  2DC8 A;  3O0U A;  2BDZ A;  4MZO A;  2H7J A;  1F2C A;  2YJC A;  4X6H A;  1YT7 A;  3PNR A;  3KWZ A;  2G6D A;  4YYQ A;  2E03 A;  1CSB B;  5CVO B;  2R9N A;  2OUL A;  2DJG B;  3P5V A;  2XU1 A;  2DZY A;  2DC7 A;  3I06 A;  2FUD A;  3CBJ A;  4YYV A;  2HH5 A;  2BDL A;  4W5C A;  1TU6 A;  4OEM A;  2R6N A;  1BGO A;  1ICF A;  1HUC B;  4G54 A;  5PAD A;  3QSD A;  1FH0 A;  3RVV A;  4N79 A;  4YYU A;  4RY2 A;  4XR7 A;  4ZUX U;  2AUZ A;  3AI8 A;  4DMX A;  1MEG A;  2JQF R;  3CBK A;  5JH3 A;  2HXZ A;  3PW3 A;  4BS6 A;  5J94 A;  3N3K A;  2IPP B;  4BPV A;  3IV2 A;  1EWM A;  3WXF A;  1STF E;  4X6J A;  3OIS A;  2P7U A;  3F75 A;  4YYS A;  4KLB A;  2AVW A;  4FK5 A;  2Y6E A;  2AYO A;  1CTE A;  1KXR A;  5EF4 A;  1U9X A;  5CHV A;  2DZZ A;  3OVZ A;  4CZW A;  3BPF A;  3K24 A;  3WXG A; 
#chains in the Genus database with same CATH topology
 3V6C A;  4X6I A;  4BOZ A;  2R9O A;  2NQD B;  4BOQ A;  3PHX A;  4MZS A;  2YJ2 A;  5EZS A;  2CB5 A;  4FJC A;  3I3T A;  2AS8 A;  2NQG A;  1SP4 B;  4PI3 A;  4P6G A;  4BS5 A;  1ZIV A;  4RKX A;  3PHU A;  1XKG A;  1U9V A;  2ARY A;  2PNS A;  4Q8H A;  3CH3 X;  3LXS A;  4MSX A;  1CVZ A;  1KFU L;  2PRE A;  4RF1 A;  4CDE B;  1EWL A;  2BU3 A;  2FYE A;  3P5W A;  3PSE A;  1GEC E;  2DJF B;  4PAD A;  2CIO A;  3BC3 A;  2XU4 A;  3P5X A;  3PHW A;  3RVX A;  2VHF A;  2VHS A;  1PXV A;  3MHS A;  4PP1 A;  2GHU A;  2O6X A;  1CV8 A;  3E9S A;  3IMA A;  5FPW A;  3P5U A;  4OVZ A;  3DF0 A;  3PRP A;  3ZUA A;  1DF0 A;  2Y5B A;  1THE A;  1U9W A;  2HHN A;  1AU0 A;  1SNK A;  4BOU A;  3BB7 A;  2XU3 A;  1AYV A;  2FQ9 A;  3HWN A;  1M6D A;  5F02 A;  1EWO A;  3U8E A;  3ZNH A;  4YYW A;  2C0Y A;  4CDF B;  3MOR A;  3KW9 A;  3BCN A;  2NQI A;  4IUM A;  4CDD B;  2NQA A;  1CS8 A;  1PPP A;  2YJB A;  1F29 A;  4I04 A;  4BOP A;  4RNA A;  3C0R A;  3HD3 A;  1DEU A;  1CQD A;  4DMY A;  1CJL A;  1NQC A;  1KHP A;  5CHT A;  3IUT A;  1ATK A;  1YVB A;  4XUI A;  2AYN A;  2FRQ A;  4AXM A;  1YAL A;  2R9M A;  4YV8 A;  3ERV A;  4WA6 A;  3H8B A;  4Q8G A;  1KFX L;  2AIM A;  3BWK A;  4OW0 A;  3H6S A;  8PCH A;  1IWD A;  3GCB A;  4D8E A;  3KX1 A;  2F7D A;  3M99 A;  4IP3 A;  1YK8 A;  3IHP A;  3OF9 A;  3QJ3 A;  2JTC A;  3K9M A;  4I07 A;  3PDF A;  1MHW A;  2FT2 A;  2OP3 A;  1BP4 A;  3HHA A;  3PBH A;  1AEC A;  1NB3 A;  2ACT A;  2B1N A;  2YJ9 A;  1YK7 A;  1PAD A;  1QMY A;  4HXD B;  3H7D A;  1PPD A;  4ZTB A;  4QRV A;  1BQI A;  1GCB A;  1CB5 A;  3W31 A;  3HHI A;  2DC6 A;  5CVM A;  1PPO A;  2DCA A;  1PCI A;  3OF8 A;  3BBA A;  4MM3 B;  4P16 A;  1MEM A;  2G8E A;  4N8W A;  1AU2 A;  3B21 A;  2B1M A;  2UZJ A;  1VSN A;  2P86 A;  1ITO A;  1BY8 A;  3BOW A;  9PAP A;  3RNV A;  1DKI A;  4M0W A;  1GMY A;  1ME4 A;  4RF0 A;  2G8J A;  1NPZ A;  4R3D A;  5JA7 A;  3IEJ A;  2DC9 A;  2FRA A;  2FO5 A;  1MDW A;  2PBH A;  4CDC B;  4D8B A;  1EF7 A;  2F1G A;  5CVN B;  3WXE A;  4OEL A;  1NB5 A;  3IOQ A;  6PAD A;  4OVZ B;  3MP2 A;  1YZB A;  2DCC A;  2JQG R;  1JQP A;  1AYU A;  1NLJ A;  1EWP A;  3S3R A;  1GLO A;  3KFQ A;  4XZX A;  7PCK A;  1ZCM A;  2P0R A;  3MJ5 A;  4AXL A;  4QRX A;  1MIR A;  1U5I A;  3O1G A;  1NL6 A;  1AIM A;  1MS6 A;  4P6E A;  1S4V A;  4GUA A;  2G7Y A;  2AU1 A;  2JRI A;  2DCD A;  2E02 A;  3S3Q A;  3C9E A;  3NHE A;  2FE8 A;  2DCB A;  3KWB X;  5JZE A;  5A24 A;  4QRG A;  1POP A;  2AUX A;  2R9C A;  2ATO A;  1TL9 A;  1K3B B;  1PVJ A;  1F2B A;  2HD5 A;  3V6E A;  4PP2 E;  4QH6 A;  4K7C A;  5K16 A;  4I05 A;  5EGW A;  1QDQ A;  1VJV A;  1A6R A;  3N4C A;  1PBH A;  1F2A A;  4HWY A;  3CH2 X;  4REZ A;  2YJ8 A;  3H8C A;  2GFO A;  3KSE A;  3MTN A;  3RVW A;  2WBF X;  4BSQ A;  4W4U A;  3N3G A;  3TNX A;  3QT4 A;  1U9Q X;  1AYW A;  1ME3 A;  2BTW A;  1AU4 A;  1AU3 A;  4YVA A;  1Y4H A;  2PAD A;  1X9Y A;  2R9F A;  3BPM A;  3D6S A;  2AGA A;  3LFY A;  1KHQ A;  4N4Z A;  4QBB A;  2BTW B;  2E01 A;  3E1Z B;  2FTD A;  1Q6K A;  3USV A;  2E00 A;  3OVX A;  1PIP A;  5E6J A;  3H89 A;  3KKU A;  1QXP A;  4FIP A;  2OZ2 A;  1Y08 A;  1QOL A;  4YYR A;  1PPN A;  3MHH A;  1TLO A;  3B79 A;  3F5V A;  2XU5 A;  3K8U A;  1CPJ A;  5EZQ A;  5KO3 A;  1O0E A;  1PE6 A;  4A5U A;  4BQV A;  2IBI A;  4W5B A;  2DC8 A;  4BOS A;  4D8I A;  3OQC A;  3O0U A;  2BDZ A;  4MZO A;  3IFU A;  2H7J A;  3O65 A;  1F2C A;  2YJC A;  4X6H A;  1YT7 A;  3PNR A;  3KWZ A;  2G6D A;  4YYQ A;  2E03 A;  1CSB B;  5CVO B;  2R9N A;  2J7Q A;  2Z84 A;  2OUL A;  2DJG B;  3P5V A;  1UKF A;  2XU1 A;  2DZY A;  2J7Q C;  2DC7 A;  3I06 A;  4WUR A;  2FUD A;  3CBJ A;  3TMP A;  4YYV A;  2HH5 A;  2BDL A;  4W5C A;  2HWK A;  1TU6 A;  4OEM A;  3TRK A;  2R6N A;  1BGO A;  1ICF A;  1HUC B;  4MI7 A;  4G54 A;  5PAD A;  1FH0 A;  3QSD A;  3RVV A;  4N79 A;  4YYU A;  4RY2 A;  4XR7 A;  4ZUX U;  2AUZ A;  3AI8 A;  4DMX A;  1MEG A;  2JQF R;  3CBK A;  5JH3 A;  2HXZ A;  3PW3 A;  4BS6 A;  5J94 A;  3N3K A;  3PT2 A;  3MTV A;  2IPP B;  4BPV A;  3IV2 A;  1EWM A;  3WXF A;  1STF E;  4X6J A;  3OIS A;  2P7U A;  3F75 A;  4YYS A;  4KLB A;  2AVW A;  4FK5 A;  2Y6E A;  2AYO A;  2DOS A;  1CTE A;  1KXR A;  5EF4 A;  1U9X A;  5CHV A;  2DZZ A;  3BY4 A;  4PT5 A;  3PRM A;  3OVZ A;  4CZW A;  3BPF A;  3K24 A;  3W30 A;  3WXG A; 
#chains in the Genus database with same CATH homology
 3V6C A;  4X6I A;  2R9O A;  2NQD B;  2VFB A;  4MZS A;  2YJ2 A;  2CB5 A;  4FJC A;  3I3T A;  2AS8 A;  2NQG A;  1SP4 B;  4PI3 A;  4P6G A;  4BS5 A;  1ZIV A;  4B55 A;  1XKG A;  1U9V A;  2ARY A;  2PNS A;  4Q8H A;  3CH3 X;  3LXS A;  4MSX A;  1CVZ A;  1KFU L;  2PRE A;  4CDE B;  1EWL A;  2FYE A;  3P5W A;  1GEC E;  2DJF B;  4PAD A;  2CIO A;  3BC3 A;  2XU4 A;  3P5X A;  3RVX A;  2VHF A;  2VHS A;  1PXV A;  3MHS A;  4PP1 A;  2GHU A;  2O6X A;  1CV8 A;  5FPW A;  3IMA A;  3P5U A;  3DF0 A;  3ZUA A;  1DF0 A;  2Y5B A;  1THE A;  1U9W A;  2HHN A;  1AU0 A;  1SNK A;  2XU3 A;  1AYV A;  2FQ9 A;  3HWN A;  1M6D A;  5F02 A;  1EWO A;  3U8E A;  4YYW A;  2C0Y A;  4CDF B;  3MOR A;  3KW9 A;  3BCN A;  2NQI A;  4CDD B;  2NQA A;  1CS8 A;  1PPP A;  2YJB A;  1F29 A;  4I04 A;  1E2T A;  3HD3 A;  1DEU A;  1CQD A;  4DMY A;  1CJL A;  1NQC A;  1KHP A;  5CHT A;  3IUT A;  1ATK A;  1YVB A;  4XUI A;  2AYN A;  2FRQ A;  4AXM A;  1YAL A;  2R9M A;  4YV8 A;  3ERV A;  4WA6 A;  3H8B A;  4Q8G A;  1KFX L;  2AIM A;  3BWK A;  3H6S A;  8PCH A;  1IWD A;  3GCB A;  3KX1 A;  2F7D A;  3M99 A;  1YK8 A;  3IHP A;  3OF9 A;  3QJ3 A;  3K9M A;  4I07 A;  3PDF A;  4C5P A;  1MHW A;  2FT2 A;  2OP3 A;  1BP4 A;  3HHA A;  3PBH A;  1AEC A;  1NB3 A;  2ACT A;  2B1N A;  2YJ9 A;  1YK7 A;  1PAD A;  1QMY A;  3H7D A;  1PPD A;  4QRV A;  1BQI A;  1GCB A;  1CB5 A;  3HHI A;  2DC6 A;  5CVM A;  1PPO A;  2DCA A;  1PCI A;  3OF8 A;  1MEM A;  2G8E A;  4N8W A;  1AU2 A;  2B1M A;  1GX3 A;  1VSN A;  2P86 A;  1ITO A;  1BY8 A;  3BOW A;  9PAP A;  1GMY A;  1ME4 A;  2G8J A;  1NPZ A;  5JA7 A;  3IEJ A;  2DC9 A;  2FRA A;  2FO5 A;  1MDW A;  2PBH A;  4CDC B;  1EF7 A;  2F1G A;  5CVN B;  3WXE A;  4OEL A;  1NB5 A;  3IOQ A;  6PAD A;  2DCC A;  2JQG R;  1JQP A;  1AYU A;  1NLJ A;  1EWP A;  3S3R A;  1GLO A;  3KFQ A;  7PCK A;  1ZCM A;  2P0R A;  4AXL A;  4QRX A;  1MIR A;  1U5I A;  3O1G A;  1NL6 A;  1AIM A;  1MS6 A;  4P6E A;  1S4V A;  2G7Y A;  2AU1 A;  2DCD A;  2E02 A;  3S3Q A;  3C9E A;  3NHE A;  1W6F A;  4GUZ A;  2DCB A;  3KWB X;  5A24 A;  4QRG A;  1POP A;  2AUX A;  4NV8 A;  2R9C A;  2ATO A;  1TL9 A;  1K3B B;  1F2B A;  2HD5 A;  3V6E A;  4PP2 E;  4QH6 A;  4K7C A;  5K16 A;  4I05 A;  5EGW A;  1QDQ A;  1VJV A;  1A6R A;  4HWY A;  1PBH A;  1F2A A;  3N4C A;  3CH2 X;  2YJ8 A;  3H8C A;  2GFO A;  3KSE A;  3MTN A;  3RVW A;  2WBF X;  3D9W A;  4BSQ A;  4W4U A;  3N3G A;  3TNX A;  3QT4 A;  1U9Q X;  1AYW A;  1ME3 A;  1AU4 A;  1AU3 A;  4YVA A;  1Y4H A;  2PAD A;  1X9Y A;  2R9F A;  3BPM A;  3D6S A;  3LFY A;  1KHQ A;  4N4Z A;  4QBB A;  2E01 A;  3E1Z B;  2FTD A;  1Q6K A;  3USV A;  2E00 A;  3OVX A;  1PIP A;  3H89 A;  3KKU A;  1QXP A;  4FIP A;  2OZ2 A;  1Y08 A;  1QOL A;  4YYR A;  1PPN A;  3MHH A;  1TLO A;  3B79 A;  3F5V A;  2XU5 A;  3K8U A;  1CPJ A;  1O0E A;  1PE6 A;  4BQV A;  1W5R A;  2IBI A;  4W5B A;  2DC8 A;  3O0U A;  2BDZ A;  4MZO A;  2H7J A;  1F2C A;  2YJC A;  4X6H A;  1YT7 A;  3PNR A;  3KWZ A;  2G6D A;  4YYQ A;  2E03 A;  1CSB B;  1W4T A;  5CVO B;  2R9N A;  2BSZ A;  2OUL A;  2DJG B;  3P5V A;  2XU1 A;  2DZY A;  2DC7 A;  3I06 A;  2FUD A;  3CBJ A;  4YYV A;  2HH5 A;  2BDL A;  4W5C A;  1TU6 A;  4OEM A;  2R6N A;  1BGO A;  1ICF A;  1HUC B;  4G54 A;  5PAD A;  3QSD A;  1FH0 A;  3RVV A;  4N79 A;  4YYU A;  4BGF A;  4RY2 A;  4XR7 A;  4ZUX U;  2AUZ A;  3AI8 A;  4DMX A;  1MEG A;  2JQF R;  4NV7 A;  3CBK A;  5JH3 A;  2HXZ A;  3PW3 A;  4BS6 A;  5J94 A;  2VFC A;  3N3K A;  2IPP B;  4BPV A;  3IV2 A;  1EWM A;  3WXF A;  1STF E;  4X6J A;  3OIS A;  2P7U A;  3F75 A;  4YYS A;  4KLB A;  2AVW A;  4FK5 A;  2Y6E A;  2AYO A;  1CTE A;  1KXR A;  5EF4 A;  1U9X A;  5CHV A;  2DZZ A;  3LTW A;  3OVZ A;  4CZW A;  3BPF A;  3K24 A;  3WXG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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