2G8JA

Calpain 1 proteolytic core in complex with snj-1945, a alpha-ketoamide-type inhibitor.
Total Genus 100
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
322
structure length
322
Chain Sequence
b'NAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICNLT'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Calpain-1 catalytic subunit
publication title Calpain Inhibition by alpha-Ketoamide and Cyclic Hemiacetal Inhibitors Revealed by X-ray Crystallography
pubmed doi rcsb
source organism Rattus norvegicus
molecule tags Hydrolase
total genus 100
structure length 322
sequence length 322
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2006-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2g8jA02
1M6DA 2BDZA 3PNRA 2VHSA 4AXLA 3HWNA 2P7UA 2DZYA 3U8EA 3BCNA 1VSNA 2YJ2A 4Q8GA 3P5XA 3V6EA 1A6RA 5J94A 2AYOA 1ZIVA 3MTNA 1KFUL 2YJCA 1AU2A 4BS6A 4MSXA 1YVBA 2E01A 5FPWA 5PADA 3HD3A 3MHHA 1YALA 1PE6A 1CS8A 4FJCA 2AUXA 1ZCMA 3CBKA 2PBHA 3KWBX 4X6IA 3IV2A 2VHFA 3CH3X 4YYRA 2FYEA 2AIMA 3D6SA 1U9VA 2HH5A 3RVVA 3WXEA 2G8JA 1MDWA 4MZOA 2FRAA 4KLBA 2E00A 2AUZA 1AIMA 5EGWA 1NPZA 2G7YA 2E03A 2YJ9A 3BWKA 4G54A 3WXFA 2Y5BA 2DC6A 4I04A 1CTEA 1AECA 4QBBA 3PBHA 2F1GA 4YV8A 2YJBA 4CDFB 1KXRA 1S4VA 4QH6A 1ME3A 2DC8A 2R9NA 3NHEA 2B1MA 3P5WA 2O6XA 4OELA 1GMYA 4N4ZA 5EF4A 1NB3A 2OP3A 1PXVA 3CH2X 4HWYA 1CSBB 3C9EA 1TL9A 3QT4A 3K24A 1PCIA 1Y08A 2IBIA 4WA6A 4QRVA 5CHTA 4N8WA 1EWOA 1KHQA 2DC9A 2XU5A 1POPA 2XU3A 4PP2E 5CVNB 2C0YA 5JH3A 1AYWA 3WXGA 3F5VA 3H8BA 3OVXA 1DEUA 1SNKA 5CVOB 2E02A 3K9MA 1QOLA 1AYVA 1AU4A 4AXMA 1PPPA 1QXPA 1NLJA 4PI3A 1BY8A 2G6DA 4CDDB 4P6GA 1SP4B 1QDQA 2JQFR 1THEA 2DCDA 1EF7A 2R9FA 1AU0A 4RY2A 4CDCB 4P6EA 3N3KA 1YK8A 2AS8A 2NQDB 2FTDA 3TNXA 2XU1A 1PADA 1Q6KA 2FUDA 1GLOA 1PBHA 2NQIA 3OVZA 4XUIA 4YYSA 2OULA 2F7DA 1DF0A 3LXSA 1PPDA 2ARYA 2DCBA 2OZ2A 3H89A 3BPFA 5CVMA 1BGOA 4YYWA 3IEJA 3S3RA 2HHNA 4YYUA 1YK7A 1STFE 5CHVA 3F75A 3MHSA 1JQPA 1K3BB 3P5VA 4X6HA 3I3TA 3IHPA 1F2BA 3H8CA 1CJLA 1U9XA 3E1ZB 6PADA 1XKGA 2GFOA 1U5IA 3KKUA 4QRGA 3LFYA 2AU1A 3N3GA 3V6CA 4DMXA 4PADA 4XR7A 3RVWA 2FO5A 3QJ3A 1AU3A 1AYUA 1F29A 3MORA 3BPMA 8PCHA 1EWPA 1MEMA 4QRXA 1BP4A 2WBFX 1KFXL 4BS5A 4FK5A 2DC7A 3B79A 1GECE 1TU6A 4YYQA 3KWZA 3ZUAA 1U9QX 2PADA 3KSEA 1PPOA 3BC3A 1NL6A 2BDLA 2YJ8A 3OISA 3IOQA 2ACTA 1EWLA 3K8UA 3CBJA 4W5CA 1VJVA 2DCAA 5K16A 2AYNA 2HXZA 4K7CA 5F02A 2P86A 4N79A 2G8EA 3USVA 2CIOA 2P0RA 3N4CA 1ME4A 3O0UA 1EWMA 2Y6EA 3P5UA 2JQGR 2XU4A 1MS6A 9PAPA 2DJGB 3H6SA 3PDFA 4OEMA 1YT7A 4FIPA 4I07A 4X6JA 4YVAA 2IPPB 3KFQA 2R9OA 1MHWA 4PP1A 2DZZA 2H7JA 4BSQA 3OF9A 4W5BA 3IUTA 2R6NA 2DJFB 7PCKA 2DCCA 3PW3A 1Y4HA 2B1NA 3KW9A 1CPJA 4DMYA 4CDEB 3KX1A 3I06A 3HHAA 3RVXA 1ATKA 1CQDA 5A24A 1PIPA 2AVWA 3QSDA 2ATOA 1BQIA 3DF0A 2PREA 4ZUXU 4I05A 2HD5A 4Q8HA 1IWDA 3O1GA 1GCBA 1NQCA 4CZWA 1MEGA 5JA7A 3OF8A 1NB5A 1ICFA 3HHIA 2PNSA 1MIRA 3BOWA 1X9YA 3IMAA 1U9WA 2FQ9A 1F2AA 4MZSA 3AI8A 1O0EA 1PPNA 1FH0A 1F2CA 2CB5A 4BPVA 4W4UA 1TLOA 4YYVA 3ERVA 1CVZA 1ITOA 2R9CA 3GCBA 4BQVA 3H7DA 1CV8A 1CB5A 3M99A 2R9MA 1HUCB 2NQGA 2NQAA 1KHPA 2GHUA 3S3QA 1QMYA 2FRQA 2FT2A
chains in the Genus database with same CATH superfamily
4P16A 1M6DA 2BDZA 3PNRA 2VHSA 4AXLA 3HWNA 2J7QA 1PVJA 2P7UA 2DZYA 3U8EA 3BCNA 1VSNA 2YJ2A 4Q8GA 3P5XA 3V6EA 1A6RA 5J94A 1DKIA 2AYOA 1ZIVA 3MTNA 1KFUL 2YJCA 1AU2A 4BS6A 4MSXA 1YVBA 2E01A 5FPWA 5PADA 3HD3A 3MHHA 1YALA 3E9SA 1PE6A 1CS8A 3PHXA 2AUXA 1ZCMA 4FJCA 3CBKA 2PBHA 4ZTBA 3KWBX 4X6IA 3IV2A 2VHFA 3CH3X 4YYRA 2FYEA 2AIMA 3PRMA 4IP3A 3D6SA 1U9VA 2HH5A 3RVVA 3WXEA 2G8JA 1MDWA 4MZOA 2FRAA 3BY4A 4KLBA 2E00A 2AUZA 4D8EA 1AIMA 5EGWA 1NPZA 2G7YA 2E03A 2YJ9A 3BWKA 4G54A 3WXFA 2Y5BA 2DC6A 4I04A 1CTEA 1AECA 5EZSA 4QBBA 2BTWA 3PBHA 2F1GA 4YV8A 4BOUA 2YJBA 4CDFB 1KXRA 1S4VA 4QH6A 1ME3A 2DC8A 2R9NA 3NHEA 1YZBA 4M0WA 2B1MA 3P5WA 2O6XA 3BBAA 4MI7A 3BB7A 4OELA 1GMYA 4N4ZA 4IUMA 5EF4A 1NB3A 5EZQA 2OP3A 1PXVA 3CH2X 4HWYA 4REZA 1CSBB 3C9EA 1TL9A 3RNVA 2HWKA 3QT4A 3K24A 1PCIA 1Y08A 2IBIA 4WA6A 2BTWB 4QRVA 5CHTA 4N8WA 1EWOA 1KHQA 2DC9A 2XU5A 1POPA 5E6JA 2XU3A 4PP2E 5CVNB 2C0YA 5JH3A 2JRIA 1AYWA 3WXGA 3F5VA 3H8BA 3OVXA 1DEUA 1SNKA 5CVOB 2E02A 3K9MA 1QOLA 1AYVA 2JTCA 3PSEA 1AU4A 4BOSA 4AXMA 4A5UA 1PPPA 1QXPA 1NLJA 5KO3A 4PI3A 1BY8A 2G6DA 4CDDB 4P6GA 4MM3B 1SP4B 1QDQA 2JQFR 1THEA 2DCDA 1EF7A 2R9FA 1AU0A 4RY2A 4CDCB 4P6EA 2Z84A 3N3KA 1YK8A 2AS8A 2NQDB 2FTDA 3TNXA 2XU1A 1PADA 1Q6KA 2FUDA 1GLOA 1PBHA 2NQIA 3OVZA 4XUIA 4YYSA 2OULA 2F7DA 1DF0A 1UKFA 3LXSA 1PPDA 2ARYA 2DCBA 2OZ2A 3H89A 3BPFA 5CVMA 1BGOA 4YYWA 3IEJA 4HXDB 3S3RA 2HHNA 4YYUA 4BOQA 1YK7A 1STFE 3B21A 5CHVA 3F75A 3MHSA 1JQPA 1K3BB 3P5VA 4X6HA 3I3TA 3IHPA 1F2BA 3H8CA 1CJLA 1U9XA 3E1ZB 6PADA 1XKGA 2GFOA 3W31A 1U5IA 3KKUA 4QRGA 3LFYA 2AU1A 3N3GA 3V6CA 3MTVA 4DMXA 4PADA 4XR7A 3PHWA 3RVWA 2FO5A 3QJ3A 1AU3A 2FE8A 1AYUA 1F29A 3MORA 3BPMA 8PCHA 1EWPA 1MEMA 4QRXA 1BP4A 2WBFX 1KFXL 4D8IA 4BS5A 2BU3A 4FK5A 2DC7A 3B79A 1GECE 1TU6A 4YYQA 3KWZA 3ZUAA 1U9QX 4WURA 2PADA 3MP2A 3KSEA 1PPOA 3BC3A 3OQCA 1NL6A 2BDLA 2YJ8A 3OISA 3IOQA 2ACTA 1EWLA 3K8UA 3CBJA 4W5CA 1VJVA 2DCAA 3MJ5A 5K16A 2AYNA 2HXZA 4K7CA 4RKXA 5F02A 2P86A 4N79A 3TMPA 2G8EA 3USVA 4RF1A 2CIOA 2P0RA 3N4CA 3O65A 4PT5A 2UZJA 1ME4A 3O0UA 1EWMA 3P5UA 3IFUA 2Y6EA 2JQGR 2XU4A 3PHUA 4BOPA 1MS6A 9PAPA 2DJGB 3H6SA 3PDFA 4OEMA 1YT7A 4FIPA 3PT2A 4I07A 4X6JA 4YVAA 2IPPB 3KFQA 2R9OA 1MHWA 4RF0A 2DOSA 4PP1A 2DZZA 2H7JA 4BSQA 3OF9A 4W5BA 3IUTA 2R6NA 2DJFB 4BOZA 7PCKA 2DCCA 3PW3A 1Y4HA 4GUAA 2B1NA 3KW9A 3TRKA 1CPJA 4DMYA 4CDEB 3KX1A 3I06A 3HHAA 3RVXA 1ATKA 1CQDA 4OW0A 5A24A 1PIPA 2AVWA 3QSDA 2ATOA 3ZNHA 3C0RA 1BQIA 4RNAA 3DF0A 2PREA 4ZUXU 2AGAA 4I05A 2HD5A 4Q8HA 1IWDA 3O1GA 1GCBA 2J7QC 1NQCA 4CZWA 1MEGA 5JA7A 4OVZA 3OF8A 1NB5A 1ICFA 3HHIA 2PNSA 1MIRA 3BOWA 1X9YA 4R3DA 3IMAA 5JZEA 1U9WA 3W30A 2FQ9A 1F2AA 4MZSA 3AI8A 1O0EA 1PPNA 1FH0A 1F2CA 2CB5A 4BPVA 3PRPA 4W4UA 1TLOA 4D8BA 4YYVA 3ERVA 1CVZA 4XZXA 1ITOA 2R9CA 3GCBA 4BQVA 3H7DA 4OVZB 1CV8A 1CB5A 3M99A 2R9MA 1HUCB 2NQGA 2NQAA 1KHPA 2GHUA 3S3QA 1QMYA 2FRQA 2FT2A
chains in the Genus database with same CATH topology
1M6DA 2BDZA 3PNRA 2VHSA 4AXLA 3HWNA 2P7UA 2DZYA 3U8EA 3BCNA 1VSNA 2YJ2A 4Q8GA 3P5XA 3V6EA 1A6RA 5J94A 2AYOA 1ZIVA 3MTNA 1KFUL 2YJCA 1AU2A 4BS6A 4MSXA 1YVBA 2E01A 5FPWA 5PADA 3HD3A 3MHHA 4BGFA 1YALA 1PE6A 1CS8A 4FJCA 2AUXA 1ZCMA 3CBKA 2PBHA 3KWBX 4X6IA 3IV2A 4NV8A 2VHFA 3CH3X 4YYRA 2FYEA 2AIMA 3D6SA 1U9VA 2HH5A 3RVVA 3WXEA 2G8JA 1MDWA 4MZOA 2FRAA 4KLBA 2E00A 2AUZA 1AIMA 5EGWA 1NPZA 2G7YA 1GX3A 2E03A 2YJ9A 3BWKA 4G54A 3WXFA 2Y5BA 2DC6A 4I04A 1CTEA 1AECA 3D9WA 4QBBA 3PBHA 2F1GA 4YV8A 2YJBA 4CDFB 1KXRA 1S4VA 4QH6A 1ME3A 2DC8A 2R9NA 3NHEA 2B1MA 3P5WA 2O6XA 4OELA 1GMYA 4N4ZA 5EF4A 1NB3A 2VFCA 2OP3A 1PXVA 3CH2X 4HWYA 1CSBB 3C9EA 1TL9A 3QT4A 3K24A 1PCIA 1Y08A 2IBIA 4WA6A 4QRVA 5CHTA 4N8WA 1EWOA 1KHQA 2DC9A 2XU5A 1POPA 2XU3A 4PP2E 5CVNB 2C0YA 5JH3A 1AYWA 3WXGA 3F5VA 3H8BA 1W6FA 3OVXA 1DEUA 1SNKA 5CVOB 2E02A 3K9MA 1QOLA 1AYVA 1AU4A 4AXMA 1PPPA 1QXPA 1NLJA 4PI3A 1BY8A 2G6DA 4CDDB 4P6GA 1SP4B 1QDQA 2JQFR 1THEA 2DCDA 1EF7A 2R9FA 4GUZA 1AU0A 4RY2A 4CDCB 3LTWA 4P6EA 3N3KA 1YK8A 2AS8A 2NQDB 2FTDA 3TNXA 2XU1A 1PADA 1Q6KA 2FUDA 1GLOA 1PBHA 2NQIA 3OVZA 4XUIA 4YYSA 2OULA 2F7DA 1DF0A 3LXSA 1PPDA 2ARYA 2DCBA 2OZ2A 3H89A 3BPFA 5CVMA 1BGOA 4YYWA 3IEJA 3S3RA 2HHNA 4YYUA 1YK7A 1STFE 5CHVA 3F75A 3MHSA 1JQPA 1K3BB 3P5VA 4X6HA 3I3TA 3IHPA 1F2BA 3H8CA 1CJLA 1U9XA 3E1ZB 6PADA 1XKGA 2GFOA 1U5IA 3KKUA 4QRGA 3LFYA 2AU1A 3N3GA 3V6CA 4DMXA 4PADA 4XR7A 4NV7A 2VFBA 3RVWA 2FO5A 3QJ3A 1AU3A 1AYUA 1F29A 3MORA 3BPMA 8PCHA 1EWPA 1MEMA 4QRXA 1BP4A 2BSZA 2WBFX 1KFXL 1E2TA 4BS5A 4FK5A 2DC7A 3B79A 4B55A 1GECE 1TU6A 4YYQA 3KWZA 3ZUAA 1U9QX 2PADA 3KSEA 1PPOA 3BC3A 1NL6A 2BDLA 2YJ8A 3OISA 3IOQA 2ACTA 4C5PA 1EWLA 3K8UA 3CBJA 4W5CA 1VJVA 2DCAA 5K16A 2AYNA 2HXZA 4K7CA 5F02A 2P86A 4N79A 2G8EA 3USVA 2CIOA 2P0RA 3N4CA 1ME4A 3O0UA 1EWMA 2Y6EA 3P5UA 2JQGR 2XU4A 1MS6A 9PAPA 2DJGB 3H6SA 3PDFA 4OEMA 1W4TA 1YT7A 4FIPA 4I07A 4X6JA 4YVAA 2IPPB 3KFQA 2R9OA 1MHWA 4PP1A 1W5RA 2DZZA 2H7JA 4BSQA 3OF9A 4W5BA 3IUTA 2R6NA 2DJFB 7PCKA 2DCCA 3PW3A 1Y4HA 2B1NA 3KW9A 1CPJA 4DMYA 4CDEB 3KX1A 3I06A 3HHAA 3RVXA 1ATKA 1CQDA 5A24A 1PIPA 2AVWA 3QSDA 2ATOA 1BQIA 3DF0A 2PREA 4ZUXU 4I05A 2HD5A 4Q8HA 1IWDA 3O1GA 1GCBA 1NQCA 4CZWA 1MEGA 5JA7A 3OF8A 1NB5A 1ICFA 3HHIA 2PNSA 1MIRA 3BOWA 1X9YA 3IMAA 1U9WA 2FQ9A 1F2AA 4MZSA 3AI8A 1O0EA 1PPNA 1FH0A 1F2CA 2CB5A 4BPVA 4W4UA 1TLOA 4YYVA 3ERVA 1CVZA 1ITOA 2R9CA 3GCBA 4BQVA 3H7DA 1CV8A 1CB5A 3M99A 2R9MA 1HUCB 2NQGA 2NQAA 1KHPA 2GHUA 3S3QA 1QMYA 2FRQA 2FT2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M6D A;  2BDZ A;  3PNR A;  2VHS A;  4AXL A;  3HWN A;  2P7U A;  2DZY A;  3U8E A;  3BCN A;  1VSN A;  2YJ2 A;  4Q8G A;  3P5X A;  3V6E A;  1A6R A;  5J94 A;  2AYO A;  1ZIV A;  3MTN A;  1KFU L;  2YJC A;  1AU2 A;  4BS6 A;  4MSX A;  1YVB A;  2E01 A;  5FPW A;  5PAD A;  3HD3 A;  3MHH A;  1YAL A;  1PE6 A;  1CS8 A;  4FJC A;  2AUX A;  1ZCM A;  3CBK A;  2PBH A;  3KWB X;  4X6I A;  3IV2 A;  2VHF A;  3CH3 X;  4YYR A;  2FYE A;  2AIM A;  3D6S A;  1U9V A;  2HH5 A;  3RVV A;  3WXE A;  2G8J A;  1MDW A;  4MZO A;  2FRA A;  4KLB A;  2E00 A;  2AUZ A;  1AIM A;  5EGW A;  1NPZ A;  2G7Y A;  2E03 A;  2YJ9 A;  3BWK A;  4G54 A;  3WXF A;  2Y5B A;  2DC6 A;  4I04 A;  1CTE A;  1AEC A;  4QBB A;  3PBH A;  2F1G A;  4YV8 A;  2YJB A;  4CDF B;  1KXR A;  1S4V A;  4QH6 A;  1ME3 A;  2DC8 A;  2R9N A;  3NHE A;  2B1M A;  3P5W A;  2O6X A;  4OEL A;  1GMY A;  4N4Z A;  5EF4 A;  1NB3 A;  2OP3 A;  1PXV A;  3CH2 X;  4HWY A;  1CSB B;  3C9E A;  1TL9 A;  3QT4 A;  3K24 A;  1PCI A;  1Y08 A;  2IBI A;  4WA6 A;  4QRV A;  5CHT A;  4N8W A;  1EWO A;  1KHQ A;  2DC9 A;  2XU5 A;  1POP A;  2XU3 A;  4PP2 E;  5CVN B;  2C0Y A;  5JH3 A;  1AYW A;  3WXG A;  3F5V A;  3H8B A;  3OVX A;  1DEU A;  1SNK A;  5CVO B;  2E02 A;  3K9M A;  1QOL A;  1AYV A;  1AU4 A;  4AXM A;  1PPP A;  1QXP A;  1NLJ A;  4PI3 A;  1BY8 A;  2G6D A;  4CDD B;  4P6G A;  1SP4 B;  1QDQ A;  2JQF R;  1THE A;  2DCD A;  1EF7 A;  2R9F A;  1AU0 A;  4RY2 A;  4CDC B;  4P6E A;  3N3K A;  1YK8 A;  2AS8 A;  2NQD B;  2FTD A;  3TNX A;  2XU1 A;  1PAD A;  1Q6K A;  2FUD A;  1GLO A;  1PBH A;  2NQI A;  3OVZ A;  4XUI A;  4YYS A;  2OUL A;  2F7D A;  1DF0 A;  3LXS A;  1PPD A;  2ARY A;  2DCB A;  2OZ2 A;  3H89 A;  3BPF A;  5CVM A;  1BGO A;  4YYW A;  3IEJ A;  3S3R A;  2HHN A;  4YYU A;  1YK7 A;  1STF E;  5CHV A;  3F75 A;  3MHS A;  1JQP A;  1K3B B;  3P5V A;  4X6H A;  3I3T A;  3IHP A;  1F2B A;  3H8C A;  1CJL A;  1U9X A;  3E1Z B;  6PAD A;  1XKG A;  2GFO A;  1U5I A;  3KKU A;  4QRG A;  3LFY A;  2AU1 A;  3N3G A;  3V6C A;  4DMX A;  4PAD A;  4XR7 A;  3RVW A;  2FO5 A;  3QJ3 A;  1AU3 A;  1AYU A;  1F29 A;  3MOR A;  3BPM A;  8PCH A;  1EWP A;  1MEM A;  4QRX A;  1BP4 A;  2WBF X;  1KFX L;  4BS5 A;  4FK5 A;  2DC7 A;  3B79 A;  1GEC E;  1TU6 A;  4YYQ A;  3KWZ A;  3ZUA A;  1U9Q X;  2PAD A;  3KSE A;  1PPO A;  3BC3 A;  1NL6 A;  2BDL A;  2YJ8 A;  3OIS A;  3IOQ A;  2ACT A;  1EWL A;  3K8U A;  3CBJ A;  4W5C A;  1VJV A;  2DCA A;  5K16 A;  2AYN A;  2HXZ A;  4K7C A;  5F02 A;  2P86 A;  4N79 A;  2G8E A;  3USV A;  2CIO A;  2P0R A;  3N4C A;  1ME4 A;  3O0U A;  1EWM A;  2Y6E A;  3P5U A;  2JQG R;  2XU4 A;  1MS6 A;  9PAP A;  2DJG B;  3H6S A;  3PDF A;  4OEM A;  1YT7 A;  4FIP A;  4I07 A;  4X6J A;  4YVA A;  2IPP B;  3KFQ A;  2R9O A;  1MHW A;  4PP1 A;  2DZZ A;  2H7J A;  4BSQ A;  3OF9 A;  4W5B A;  3IUT A;  2R6N A;  2DJF B;  7PCK A;  2DCC A;  3PW3 A;  1Y4H A;  2B1N A;  3KW9 A;  1CPJ A;  4DMY A;  4CDE B;  3KX1 A;  3I06 A;  3HHA A;  3RVX A;  1ATK A;  1CQD A;  5A24 A;  1PIP A;  2AVW A;  3QSD A;  2ATO A;  1BQI A;  3DF0 A;  2PRE A;  4ZUX U;  4I05 A;  2HD5 A;  4Q8H A;  1IWD A;  3O1G A;  1GCB A;  1NQC A;  4CZW A;  1MEG A;  5JA7 A;  3OF8 A;  1NB5 A;  1ICF A;  3HHI A;  2PNS A;  1MIR A;  3BOW A;  1X9Y A;  3IMA A;  1U9W A;  2FQ9 A;  1F2A A;  4MZS A;  3AI8 A;  1O0E A;  1PPN A;  1FH0 A;  1F2C A;  2CB5 A;  4BPV A;  4W4U A;  1TLO A;  4YYV A;  3ERV A;  1CVZ A;  1ITO A;  2R9C A;  3GCB A;  4BQV A;  3H7D A;  1CV8 A;  1CB5 A;  3M99 A;  2R9M A;  1HUC B;  2NQG A;  2NQA A;  1KHP A;  2GHU A;  3S3Q A;  1QMY A;  2FRQ A;  2FT2 A; 
#chains in the Genus database with same CATH topology
 4P16 A;  1M6D A;  2BDZ A;  3PNR A;  2VHS A;  4AXL A;  3HWN A;  2J7Q A;  1PVJ A;  2P7U A;  2DZY A;  3U8E A;  3BCN A;  1VSN A;  2YJ2 A;  4Q8G A;  3P5X A;  3V6E A;  1A6R A;  5J94 A;  1DKI A;  2AYO A;  1ZIV A;  3MTN A;  1KFU L;  2YJC A;  1AU2 A;  4BS6 A;  4MSX A;  1YVB A;  2E01 A;  5FPW A;  5PAD A;  3HD3 A;  3MHH A;  1YAL A;  3E9S A;  1PE6 A;  1CS8 A;  3PHX A;  2AUX A;  1ZCM A;  4FJC A;  3CBK A;  2PBH A;  4ZTB A;  3KWB X;  4X6I A;  3IV2 A;  2VHF A;  3CH3 X;  4YYR A;  2FYE A;  2AIM A;  3PRM A;  4IP3 A;  3D6S A;  1U9V A;  2HH5 A;  3RVV A;  3WXE A;  2G8J A;  1MDW A;  4MZO A;  2FRA A;  3BY4 A;  4KLB A;  2E00 A;  2AUZ A;  4D8E A;  1AIM A;  5EGW A;  1NPZ A;  2G7Y A;  2E03 A;  2YJ9 A;  3BWK A;  4G54 A;  3WXF A;  2Y5B A;  2DC6 A;  4I04 A;  1CTE A;  1AEC A;  5EZS A;  4QBB A;  2BTW A;  3PBH A;  2F1G A;  4YV8 A;  4BOU A;  2YJB A;  4CDF B;  1KXR A;  1S4V A;  4QH6 A;  1ME3 A;  2DC8 A;  2R9N A;  3NHE A;  1YZB A;  4M0W A;  2B1M A;  3P5W A;  2O6X A;  3BBA A;  4MI7 A;  3BB7 A;  4OEL A;  1GMY A;  4N4Z A;  4IUM A;  5EF4 A;  1NB3 A;  5EZQ A;  2OP3 A;  1PXV A;  3CH2 X;  4HWY A;  4REZ A;  1CSB B;  3C9E A;  1TL9 A;  3RNV A;  2HWK A;  3QT4 A;  3K24 A;  1PCI A;  1Y08 A;  2IBI A;  4WA6 A;  2BTW B;  4QRV A;  5CHT A;  4N8W A;  1EWO A;  1KHQ A;  2DC9 A;  2XU5 A;  1POP A;  5E6J A;  2XU3 A;  4PP2 E;  5CVN B;  2C0Y A;  5JH3 A;  2JRI A;  1AYW A;  3WXG A;  3F5V A;  3H8B A;  3OVX A;  1DEU A;  1SNK A;  5CVO B;  2E02 A;  3K9M A;  1QOL A;  1AYV A;  2JTC A;  3PSE A;  1AU4 A;  4BOS A;  4AXM A;  4A5U A;  1PPP A;  1QXP A;  1NLJ A;  5KO3 A;  4PI3 A;  1BY8 A;  2G6D A;  4CDD B;  4P6G A;  4MM3 B;  1SP4 B;  1QDQ A;  2JQF R;  1THE A;  2DCD A;  1EF7 A;  2R9F A;  1AU0 A;  4RY2 A;  4CDC B;  4P6E A;  2Z84 A;  3N3K A;  1YK8 A;  2AS8 A;  2NQD B;  2FTD A;  3TNX A;  2XU1 A;  1PAD A;  1Q6K A;  2FUD A;  1GLO A;  1PBH A;  2NQI A;  3OVZ A;  4XUI A;  4YYS A;  2OUL A;  2F7D A;  1DF0 A;  1UKF A;  3LXS A;  1PPD A;  2ARY A;  2DCB A;  2OZ2 A;  3H89 A;  3BPF A;  5CVM A;  1BGO A;  4YYW A;  3IEJ A;  4HXD B;  3S3R A;  2HHN A;  4YYU A;  4BOQ A;  1YK7 A;  1STF E;  3B21 A;  5CHV A;  3F75 A;  3MHS A;  1JQP A;  1K3B B;  3P5V A;  4X6H A;  3I3T A;  3IHP A;  1F2B A;  3H8C A;  1CJL A;  1U9X A;  3E1Z B;  6PAD A;  1XKG A;  2GFO A;  3W31 A;  1U5I A;  3KKU A;  4QRG A;  3LFY A;  2AU1 A;  3N3G A;  3V6C A;  3MTV A;  4DMX A;  4PAD A;  4XR7 A;  3PHW A;  3RVW A;  2FO5 A;  3QJ3 A;  1AU3 A;  2FE8 A;  1AYU A;  1F29 A;  3MOR A;  3BPM A;  8PCH A;  1EWP A;  1MEM A;  4QRX A;  1BP4 A;  2WBF X;  1KFX L;  4D8I A;  4BS5 A;  2BU3 A;  4FK5 A;  2DC7 A;  3B79 A;  1GEC E;  1TU6 A;  4YYQ A;  3KWZ A;  3ZUA A;  1U9Q X;  4WUR A;  2PAD A;  3MP2 A;  3KSE A;  1PPO A;  3BC3 A;  3OQC A;  1NL6 A;  2BDL A;  2YJ8 A;  3OIS A;  3IOQ A;  2ACT A;  1EWL A;  3K8U A;  3CBJ A;  4W5C A;  1VJV A;  2DCA A;  3MJ5 A;  5K16 A;  2AYN A;  2HXZ A;  4K7C A;  4RKX A;  5F02 A;  2P86 A;  4N79 A;  3TMP A;  2G8E A;  3USV A;  4RF1 A;  2CIO A;  2P0R A;  3N4C A;  3O65 A;  4PT5 A;  2UZJ A;  1ME4 A;  3O0U A;  1EWM A;  3P5U A;  3IFU A;  2Y6E A;  2JQG R;  2XU4 A;  3PHU A;  4BOP A;  1MS6 A;  9PAP A;  2DJG B;  3H6S A;  3PDF A;  4OEM A;  1YT7 A;  4FIP A;  3PT2 A;  4I07 A;  4X6J A;  4YVA A;  2IPP B;  3KFQ A;  2R9O A;  1MHW A;  4RF0 A;  2DOS A;  4PP1 A;  2DZZ A;  2H7J A;  4BSQ A;  3OF9 A;  4W5B A;  3IUT A;  2R6N A;  2DJF B;  4BOZ A;  7PCK A;  2DCC A;  3PW3 A;  1Y4H A;  4GUA A;  2B1N A;  3KW9 A;  3TRK A;  1CPJ A;  4DMY A;  4CDE B;  3KX1 A;  3I06 A;  3HHA A;  3RVX A;  1ATK A;  1CQD A;  4OW0 A;  5A24 A;  1PIP A;  2AVW A;  3QSD A;  2ATO A;  3ZNH A;  3C0R A;  1BQI A;  4RNA A;  3DF0 A;  2PRE A;  4ZUX U;  2AGA A;  4I05 A;  2HD5 A;  4Q8H A;  1IWD A;  3O1G A;  1GCB A;  2J7Q C;  1NQC A;  4CZW A;  1MEG A;  5JA7 A;  4OVZ A;  3OF8 A;  1NB5 A;  1ICF A;  3HHI A;  2PNS A;  1MIR A;  3BOW A;  1X9Y A;  4R3D A;  3IMA A;  5JZE A;  1U9W A;  3W30 A;  2FQ9 A;  1F2A A;  4MZS A;  3AI8 A;  1O0E A;  1PPN A;  1FH0 A;  1F2C A;  2CB5 A;  4BPV A;  3PRP A;  4W4U A;  1TLO A;  4D8B A;  4YYV A;  3ERV A;  1CVZ A;  4XZX A;  1ITO A;  2R9C A;  3GCB A;  4BQV A;  3H7D A;  4OVZ B;  1CV8 A;  1CB5 A;  3M99 A;  2R9M A;  1HUC B;  2NQG A;  2NQA A;  1KHP A;  2GHU A;  3S3Q A;  1QMY A;  2FRQ A;  2FT2 A; 
#chains in the Genus database with same CATH homology
 1M6D A;  2BDZ A;  3PNR A;  2VHS A;  4AXL A;  3HWN A;  2P7U A;  2DZY A;  3U8E A;  3BCN A;  1VSN A;  2YJ2 A;  4Q8G A;  3P5X A;  3V6E A;  1A6R A;  5J94 A;  2AYO A;  1ZIV A;  3MTN A;  1KFU L;  2YJC A;  1AU2 A;  4BS6 A;  4MSX A;  1YVB A;  2E01 A;  5FPW A;  5PAD A;  3HD3 A;  3MHH A;  4BGF A;  1YAL A;  1PE6 A;  1CS8 A;  4FJC A;  2AUX A;  1ZCM A;  3CBK A;  2PBH A;  3KWB X;  4X6I A;  3IV2 A;  4NV8 A;  2VHF A;  3CH3 X;  4YYR A;  2FYE A;  2AIM A;  3D6S A;  1U9V A;  2HH5 A;  3RVV A;  3WXE A;  2G8J A;  1MDW A;  4MZO A;  2FRA A;  4KLB A;  2E00 A;  2AUZ A;  1AIM A;  5EGW A;  1NPZ A;  2G7Y A;  1GX3 A;  2E03 A;  2YJ9 A;  3BWK A;  4G54 A;  3WXF A;  2Y5B A;  2DC6 A;  4I04 A;  1CTE A;  1AEC A;  3D9W A;  4QBB A;  3PBH A;  2F1G A;  4YV8 A;  2YJB A;  4CDF B;  1KXR A;  1S4V A;  4QH6 A;  1ME3 A;  2DC8 A;  2R9N A;  3NHE A;  2B1M A;  3P5W A;  2O6X A;  4OEL A;  1GMY A;  4N4Z A;  5EF4 A;  1NB3 A;  2VFC A;  2OP3 A;  1PXV A;  3CH2 X;  4HWY A;  1CSB B;  3C9E A;  1TL9 A;  3QT4 A;  3K24 A;  1PCI A;  1Y08 A;  2IBI A;  4WA6 A;  4QRV A;  5CHT A;  4N8W A;  1EWO A;  1KHQ A;  2DC9 A;  2XU5 A;  1POP A;  2XU3 A;  4PP2 E;  5CVN B;  2C0Y A;  5JH3 A;  1AYW A;  3WXG A;  3F5V A;  3H8B A;  1W6F A;  3OVX A;  1DEU A;  1SNK A;  5CVO B;  2E02 A;  3K9M A;  1QOL A;  1AYV A;  1AU4 A;  4AXM A;  1PPP A;  1QXP A;  1NLJ A;  4PI3 A;  1BY8 A;  2G6D A;  4CDD B;  4P6G A;  1SP4 B;  1QDQ A;  2JQF R;  1THE A;  2DCD A;  1EF7 A;  2R9F A;  4GUZ A;  1AU0 A;  4RY2 A;  4CDC B;  3LTW A;  4P6E A;  3N3K A;  1YK8 A;  2AS8 A;  2NQD B;  2FTD A;  3TNX A;  2XU1 A;  1PAD A;  1Q6K A;  2FUD A;  1GLO A;  1PBH A;  2NQI A;  3OVZ A;  4XUI A;  4YYS A;  2OUL A;  2F7D A;  1DF0 A;  3LXS A;  1PPD A;  2ARY A;  2DCB A;  2OZ2 A;  3H89 A;  3BPF A;  5CVM A;  1BGO A;  4YYW A;  3IEJ A;  3S3R A;  2HHN A;  4YYU A;  1YK7 A;  1STF E;  5CHV A;  3F75 A;  3MHS A;  1JQP A;  1K3B B;  3P5V A;  4X6H A;  3I3T A;  3IHP A;  1F2B A;  3H8C A;  1CJL A;  1U9X A;  3E1Z B;  6PAD A;  1XKG A;  2GFO A;  1U5I A;  3KKU A;  4QRG A;  3LFY A;  2AU1 A;  3N3G A;  3V6C A;  4DMX A;  4PAD A;  4XR7 A;  4NV7 A;  2VFB A;  3RVW A;  2FO5 A;  3QJ3 A;  1AU3 A;  1AYU A;  1F29 A;  3MOR A;  3BPM A;  8PCH A;  1EWP A;  1MEM A;  4QRX A;  1BP4 A;  2BSZ A;  2WBF X;  1KFX L;  1E2T A;  4BS5 A;  4FK5 A;  2DC7 A;  3B79 A;  4B55 A;  1GEC E;  1TU6 A;  4YYQ A;  3KWZ A;  3ZUA A;  1U9Q X;  2PAD A;  3KSE A;  1PPO A;  3BC3 A;  1NL6 A;  2BDL A;  2YJ8 A;  3OIS A;  3IOQ A;  2ACT A;  4C5P A;  1EWL A;  3K8U A;  3CBJ A;  4W5C A;  1VJV A;  2DCA A;  5K16 A;  2AYN A;  2HXZ A;  4K7C A;  5F02 A;  2P86 A;  4N79 A;  2G8E A;  3USV A;  2CIO A;  2P0R A;  3N4C A;  1ME4 A;  3O0U A;  1EWM A;  2Y6E A;  3P5U A;  2JQG R;  2XU4 A;  1MS6 A;  9PAP A;  2DJG B;  3H6S A;  3PDF A;  4OEM A;  1W4T A;  1YT7 A;  4FIP A;  4I07 A;  4X6J A;  4YVA A;  2IPP B;  3KFQ A;  2R9O A;  1MHW A;  4PP1 A;  1W5R A;  2DZZ A;  2H7J A;  4BSQ A;  3OF9 A;  4W5B A;  3IUT A;  2R6N A;  2DJF B;  7PCK A;  2DCC A;  3PW3 A;  1Y4H A;  2B1N A;  3KW9 A;  1CPJ A;  4DMY A;  4CDE B;  3KX1 A;  3I06 A;  3HHA A;  3RVX A;  1ATK A;  1CQD A;  5A24 A;  1PIP A;  2AVW A;  3QSD A;  2ATO A;  1BQI A;  3DF0 A;  2PRE A;  4ZUX U;  4I05 A;  2HD5 A;  4Q8H A;  1IWD A;  3O1G A;  1GCB A;  1NQC A;  4CZW A;  1MEG A;  5JA7 A;  3OF8 A;  1NB5 A;  1ICF A;  3HHI A;  2PNS A;  1MIR A;  3BOW A;  1X9Y A;  3IMA A;  1U9W A;  2FQ9 A;  1F2A A;  4MZS A;  3AI8 A;  1O0E A;  1PPN A;  1FH0 A;  1F2C A;  2CB5 A;  4BPV A;  4W4U A;  1TLO A;  4YYV A;  3ERV A;  1CVZ A;  1ITO A;  2R9C A;  3GCB A;  4BQV A;  3H7D A;  1CV8 A;  1CB5 A;  3M99 A;  2R9M A;  1HUC B;  2NQG A;  2NQA A;  1KHP A;  2GHU A;  3S3Q A;  1QMY A;  2FRQ A;  2FT2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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