2G8JA

Calpain 1 proteolytic core in complex with snj-1945, a alpha-ketoamide-type inhibitor.
Total Genus 100
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
322
structure length
322
Chain Sequence
NAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICNLT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Calpain Inhibition by alpha-Ketoamide and Cyclic Hemiacetal Inhibitors Revealed by X-ray Crystallography
pubmed doi rcsb
molecule tags Hydrolase
source organism Rattus norvegicus
molecule keywords Calpain-1 catalytic subunit
total genus 100
structure length 322
sequence length 322
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2006-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2g8jA02
4W5BA 2DZYA 3O1GA 2NQGA 3QJ3A 1KFUL 3C9EA 3I3TA 1K3BB 3HHAA 3WXGA 2NQIA 4YYVA 2R6NA 3I06A 3PW3A 2DJGB 1NL6A 2P0RA 1GCBA 2G8EA 3N3GA 3QSDA 4Q8GA 4BQVA 3KWBX 4BS5A 4KLBA 2P7UA 2IBIA 2YJCA 1EWLA 2GHUA 2PNSA 1PIPA 2G7YA 1KHPA 1QDQA 1ME4A 3IMAA 2XU3A 4P6EA 2FQ9A 3P5UA 2E01A 2B1NA 3QT4A 2FTDA 2ARYA 1F2BA 6PADA 3HHIA 2BDLA 3OVXA 3WXEA 4CDCB 2XU4A 2F7DA 1Q6KA 3CBKA 3P5XA 2DC6A 2HHNA 1PBHA 4DMXA 2FO5A 4G54A 3OISA 4YYSA 1A6RA 3P5VA 2YJ2A 4MSXA 1PPDA 1AECA 2AVWA 3GCBA 4QRVA 2YJ8A 4QRGA 2BDZA 5CVOB 2AS8A 1EWPA 4FIPA 2OZ2A 3IHPA 3RVWA 2PREA 4PADA 2R9FA 4P6GA 1ITOA 4BS6A 1ICFA 3TNXA 1ME3A 1SNKA 2FYEA 5EGWA 3CH2X 2DC7A 2JQFR 2CB5A 1AYUA 4OELA 2G8JA 1F29A 3BPFA 2Y6EA 1KFXL 1X9YA 3IV2A 4BPVA 2FUDA 3IUTA 1THEA 3LFYA 2Y5BA 1U9QX 2R9OA 3KSEA 2NQAA 2NQDB 3MTNA 1TU6A 3PNRA 3PDFA 3M99A 5A24A 1MHWA 4YYUA 4QBBA 4I04A 2AUXA 1AYWA 1ZCMA 3KWZA 1QOLA 3E1ZB 4X6IA 2IPPB 3CH3X 4BSQA 4W4UA 4AXLA 4W5CA 1NB5A 2R9CA 3H89A 1ZIVA 2HH5A 1BGOA 2XU1A 1AU3A 2FRAA 4FK5A 4OEMA 2OP3A 1PADA 2B1MA 4YV8A 3S3QA 1IWDA 3F5VA 4DMYA 1U9VA 1CPJA 2F1GA 3ZUAA 1BQIA 4MZOA 1M6DA 3B79A 3N3KA 1EF7A 1PPPA 4YVAA 3AI8A 3S3RA 2JQGR 1AU2A 3OF8A 3HWNA 5CVMA 1CQDA 1VSNA 1KHQA 4RY2A 9PAPA 1NLJA 4MZSA 1PCIA 3BOWA 4I05A 4FJCA 2P86A 3RVVA 3BC3A 3KW9A 4CDDB 2DCAA 1AIMA 5JA7A 1Y4HA 2HD5A 1PE6A 3NHEA 4X6HA 1YK8A 2YJ9A 1BY8A 4X6JA 1CSBB 1QMYA 1F2AA 2G6DA 4AXMA 1MEMA 1Y08A 4XUIA 1QXPA 2VHSA 4N8WA 1JQPA 1YT7A 4PP1A 1KXRA 1U9XA 1POPA 1MS6A 2AUZA 3H8CA 3K9MA 4WA6A 1F2CA 1AU4A 2E02A 1U5IA 3PBHA 5EF4A 2HXZA 3IEJA 2C0YA 1SP4B 4I07A 5CHVA 2DCCA 1PXVA 1HUCB 2DC9A 2WBFX 1NQCA 3U8EA 1S4VA 2E00A 1CTEA 7PCKA 2AU1A 3HD3A 1CV8A 4CDFB 2DZZA 2ATOA 4PP2E 8PCHA 1PPNA 1YALA 2E03A 2PADA 3K24A 2VHFA 3V6CA 2YJBA 1AYVA 2FRQA 3D6SA 4QRXA 3P5WA 3KKUA 4HWYA 1GECE 3MHSA 3V6EA 1MEGA 2AYOA 3USVA 4PI3A 1FH0A 1YVBA 5PADA 3OF9A 5J94A 3K8UA 1DEUA 3F75A 1GMYA 3WXFA 1U9WA 4CDEB 3BWKA 1MIRA 4QH6A 3ERVA 1TLOA 2DC8A 2GFOA 2R9NA 1NPZA 1YK7A 4YYQA 5FPWA 1CB5A 2R9MA 2DJFB 2XU5A 3N4CA 2H7JA 4N79A 1PPOA 3KFQA 1CVZA 1BP4A 1EWOA 1ATKA 1GLOA 4YYRA 3RVXA 1O0EA 2OULA 2DCBA 3OVZA 1MDWA 2AYNA 2DCDA 5CHTA 4CZWA 4K7CA 2AIMA 5K16A 4YYWA 1CS8A 1XKGA 3MORA 4N4ZA 3H7DA 3H8BA 3LXSA 1AU0A 5CVNB 2ACTA 1CJLA 1NB3A 4Q8HA 3O0UA 1VJVA 3BPMA 3IOQA 2PBHA 5F02A 3H6SA 4XR7A 1DF0A 2CIOA 2FT2A 1TL9A 3KX1A 3MHHA 2O6XA 4ZUXU 3CBJA 3BCNA 5JH3A 3DF0A 1EWMA 1STFE
chains in the Genus database with same CATH superfamily
4W5BA 2DZYA 3O1GA 2NQGA 3QJ3A 1KFUL 3C9EA 3I3TA 1K3BB 3HHAA 3WXGA 2NQIA 4YYVA 4D8BA 2R6NA 3MTVA 3I06A 4D8IA 3PW3A 2DJGB 1NL6A 2P0RA 1GCBA 3B21A 2G8EA 3N3GA 3QSDA 4Q8GA 4BQVA 3KWBX 4BS5A 4BOPA 4KLBA 2P7UA 2IBIA 2YJCA 1EWLA 2GHUA 2PNSA 1PIPA 2G7YA 1KHPA 1QDQA 3BBAA 1ME4A 3IMAA 2XU3A 4P6EA 2FQ9A 3P5UA 2E01A 2B1NA 3QT4A 3TMPA 2FTDA 2BTWB 2ARYA 1F2BA 6PADA 3HHIA 2BDLA 3OVXA 1UKFA 3WXEA 4CDCB 2XU4A 2F7DA 1Q6KA 3CBKA 3P5XA 2DC6A 2HHNA 1PBHA 4DMXA 2FO5A 4G54A 3OISA 4YYSA 1A6RA 5KO3A 3P5VA 2YJ2A 4MSXA 1PPDA 1AECA 2AVWA 4R3DA 3GCBA 4QRVA 2JTCA 2YJ8A 4QRGA 2BDZA 4RNAA 5CVOB 2AS8A 4BOUA 1EWPA 4FIPA 4BOQA 2OZ2A 3IHPA 3RVWA 2PREA 4PADA 2R9FA 4P6GA 1ITOA 4BS6A 1YZBA 2JRIA 1ICFA 3TNXA 3PT2A 1ME3A 1SNKA 3PHUA 5E6JA 2FYEA 5EGWA 3CH2X 2DC7A 4D8EA 2JQFR 2CB5A 1AYUA 4OELA 2G8JA 1F29A 3BPFA 2Y6EA 1KFXL 1X9YA 3IV2A 4BPVA 2FUDA 3IUTA 1THEA 3LFYA 4IUMA 2Y5BA 1U9QX 2R9OA 3KSEA 2NQAA 2NQDB 3MTNA 1TU6A 3PNRA 2J7QC 3PDFA 4PT5A 3TRKA 3M99A 5A24A 1MHWA 4YYUA 4QBBA 4I04A 2AUXA 2HWKA 1AYWA 1ZCMA 3KWZA 3OQCA 1QOLA 3E1ZB 3BB7A 4RKXA 4X6IA 2IPPB 3CH3X 4BSQA 4W4UA 4AXLA 4W5CA 1NB5A 2R9CA 3H89A 1ZIVA 2HH5A 1DKIA 1BGOA 2XU1A 1AU3A 2J7QA 2FRAA 4HXDB 4FK5A 4OEMA 2OP3A 1PADA 2B1MA 4YV8A 3S3QA 1IWDA 3F5VA 4DMYA 4OVZA 1U9VA 1CPJA 2F1GA 3ZUAA 1BQIA 4MZOA 1M6DA 3B79A 3N3KA 4A5UA 1EF7A 1PPPA 3W30A 3AI8A 4YVAA 3S3RA 2JQGR 1AU2A 3OF8A 3HWNA 5CVMA 1CQDA 1VSNA 1KHQA 4MM3B 4RY2A 9PAPA 1NLJA 4MZSA 1PCIA 3BOWA 4I05A 4FJCA 2P86A 3RVVA 4XZXA 3BC3A 3KW9A 4MI7A 4CDDB 2DCAA 1AIMA 5JA7A 1Y4HA 2HD5A 4BOZA 1PE6A 3NHEA 4X6HA 1YK8A 2YJ9A 3PSEA 1BY8A 4X6JA 1CSBB 1QMYA 1F2AA 2G6DA 4IP3A 4AXMA 1MEMA 1Y08A 4XUIA 1QXPA 2VHSA 3PRPA 4N8WA 5JZEA 4RF0A 1JQPA 1YT7A 4PP1A 1KXRA 1U9XA 1POPA 1MS6A 2AUZA 3O65A 3H8CA 3K9MA 4WA6A 1F2CA 4P16A 1AU4A 2E02A 1U5IA 3PBHA 5EF4A 2HXZA 3IEJA 2DOSA 2C0YA 3IFUA 4REZA 1SP4B 4I07A 5CHVA 2DCCA 1PXVA 1HUCB 2DC9A 2WBFX 1NQCA 3U8EA 1S4VA 2E00A 4ZTBA 1CTEA 7PCKA 2AU1A 2AGAA 3RNVA 3HD3A 1CV8A 4CDFB 2DZZA 2ATOA 4PP2E 8PCHA 1PPNA 1YALA 2E03A 2PADA 3K24A 4OVZB 2VHFA 3V6CA 2YJBA 1AYVA 2BU3A 2FRQA 4BOSA 3D6SA 4QRXA 3P5WA 3KKUA 3PHWA 1GECE 3MHSA 4HWYA 3V6EA 3BY4A 1MEGA 2AYOA 3USVA 4PI3A 1FH0A 1YVBA 5PADA 3OF9A 5J94A 2FE8A 1DEUA 3K8UA 5EZSA 2UZJA 3F75A 1GMYA 3WXFA 1U9WA 4CDEB 3BWKA 4OW0A 1MIRA 4QH6A 3ERVA 1TLOA 2DC8A 2GFOA 2R9NA 3MJ5A 1PVJA 1NPZA 2BTWA 1YK7A 4YYQA 4WURA 5FPWA 4RF1A 1CB5A 2R9MA 2DJFB 3MP2A 2XU5A 3E9SA 3N4CA 2H7JA 4N79A 1PPOA 3KFQA 1CVZA 5EZQA 1BP4A 1EWOA 1ATKA 1GLOA 4YYRA 3RVXA 1O0EA 2OULA 2DCBA 3OVZA 1MDWA 2AYNA 3PRMA 2DCDA 5CHTA 4CZWA 4K7CA 2AIMA 5K16A 4YYWA 1CS8A 2Z84A 1XKGA 3MORA 4N4ZA 3C0RA 3H7DA 3H8BA 3LXSA 1AU0A 3W31A 5CVNB 2ACTA 4GUAA 1CJLA 1NB3A 4Q8HA 3O0UA 1VJVA 3BPMA 3IOQA 2PBHA 5F02A 3H6SA 4XR7A 1DF0A 4M0WA 2CIOA 2FT2A 1TL9A 3KX1A 3PHXA 3MHHA 2O6XA 3ZNHA 4ZUXU 3CBJA 3BCNA 5JH3A 3DF0A 1EWMA 1STFE
chains in the Genus database with same CATH topology
4W5BA 2DZYA 3O1GA 2NQGA 3QJ3A 1KFUL 4BGFA 3C9EA 3I3TA 1K3BB 3HHAA 3WXGA 2NQIA 4YYVA 2R6NA 3I06A 3PW3A 2DJGB 1NL6A 2P0RA 1GCBA 2G8EA 3N3GA 3QSDA 4Q8GA 4BQVA 3KWBX 4BS5A 4KLBA 1W6FA 2IBIA 2P7UA 2YJCA 1EWLA 1W4TA 2GHUA 2PNSA 1PIPA 2G7YA 1KHPA 1QDQA 1ME4A 3IMAA 2XU3A 4P6EA 2FQ9A 3P5UA 2E01A 2B1NA 3QT4A 2FTDA 2ARYA 1F2BA 6PADA 3HHIA 2BDLA 3OVXA 3WXEA 4CDCB 2XU4A 2F7DA 1Q6KA 3CBKA 3P5XA 2DC6A 2HHNA 1PBHA 4DMXA 2FO5A 4G54A 3OISA 4YYSA 1A6RA 3P5VA 2YJ2A 4MSXA 1PPDA 1AECA 2AVWA 3GCBA 4QRVA 2YJ8A 4QRGA 2BDZA 5CVOB 2AS8A 1EWPA 4FIPA 2OZ2A 3IHPA 3RVWA 2PREA 4PADA 2R9FA 4P6GA 1ITOA 4BS6A 1ICFA 3TNXA 1ME3A 1SNKA 2FYEA 5EGWA 3CH2X 2DC7A 2JQFR 2CB5A 1AYUA 4OELA 2G8JA 1F29A 3BPFA 2Y6EA 1KFXL 1X9YA 3IV2A 4BPVA 2FUDA 3IUTA 1THEA 3LFYA 2Y5BA 1U9QX 2R9OA 3KSEA 2NQAA 2NQDB 3MTNA 1TU6A 3PNRA 3PDFA 3M99A 5A24A 1MHWA 4YYUA 4QBBA 4I04A 2AUXA 1AYWA 1ZCMA 3KWZA 1QOLA 3E1ZB 4X6IA 2IPPB 3CH3X 4BSQA 4W4UA 4AXLA 4W5CA 1NB5A 2R9CA 3H89A 1ZIVA 2HH5A 1BGOA 2XU1A 1AU3A 2FRAA 4FK5A 4OEMA 2OP3A 1PADA 2B1MA 4YV8A 3S3QA 1IWDA 3F5VA 4DMYA 1U9VA 1CPJA 2F1GA 3ZUAA 1BQIA 4MZOA 1M6DA 3B79A 3N3KA 1EF7A 1PPPA 4YVAA 3AI8A 4B55A 3S3RA 2JQGR 1AU2A 3OF8A 3HWNA 5CVMA 1CQDA 1VSNA 1KHQA 1GX3A 4RY2A 9PAPA 1NLJA 4MZSA 1PCIA 3BOWA 4I05A 4FJCA 1E2TA 2P86A 3RVVA 3BC3A 3KW9A 4CDDB 2DCAA 1AIMA 5JA7A 1Y4HA 2HD5A 1PE6A 3NHEA 4X6HA 1YK8A 2YJ9A 4NV8A 1BY8A 4X6JA 1CSBB 2VFCA 1QMYA 1F2AA 2G6DA 4AXMA 1MEMA 1Y08A 4XUIA 1QXPA 2VHSA 4N8WA 1JQPA 1YT7A 4PP1A 1KXRA 1U9XA 1POPA 1MS6A 2AUZA 3H8CA 3K9MA 4WA6A 1F2CA 1AU4A 2E02A 1U5IA 3PBHA 5EF4A 2HXZA 3IEJA 2C0YA 3LTWA 1SP4B 4I07A 5CHVA 2DCCA 1PXVA 1HUCB 2DC9A 2WBFX 1NQCA 3U8EA 1S4VA 2E00A 1CTEA 2BSZA 7PCKA 2AU1A 3HD3A 1CV8A 4CDFB 2DZZA 2ATOA 4PP2E 8PCHA 1PPNA 1YALA 2E03A 2PADA 3K24A 2VHFA 3V6CA 2YJBA 1AYVA 2FRQA 3D6SA 4QRXA 3P5WA 3KKUA 4HWYA 1GECE 3MHSA 3V6EA 1MEGA 2AYOA 3USVA 4PI3A 1FH0A 1YVBA 5PADA 3OF9A 5J94A 3K8UA 1DEUA 4C5PA 3F75A 1GMYA 3WXFA 1U9WA 4CDEB 3BWKA 1MIRA 4QH6A 3ERVA 4NV7A 1TLOA 2DC8A 2GFOA 2R9NA 1NPZA 2VFBA 1YK7A 4YYQA 5FPWA 1CB5A 2R9MA 2DJFB 2XU5A 3N4CA 2H7JA 4N79A 1PPOA 3KFQA 1CVZA 1BP4A 1EWOA 1ATKA 1GLOA 4YYRA 3RVXA 1O0EA 2OULA 2DCBA 3OVZA 1MDWA 2AYNA 2DCDA 5CHTA 4CZWA 4K7CA 2AIMA 5K16A 4YYWA 1CS8A 1XKGA 3MORA 4N4ZA 3H7DA 1W5RA 3H8BA 3LXSA 1AU0A 5CVNB 2ACTA 4GUZA 1CJLA 1NB3A 4Q8HA 3O0UA 1VJVA 3BPMA 3IOQA 2PBHA 5F02A 3H6SA 4XR7A 1DF0A 2CIOA 2FT2A 1TL9A 3KX1A 3MHHA 2O6XA 4ZUXU 3D9WA 3CBJA 3BCNA 5JH3A 3DF0A 1EWMA 1STFE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4W5B A;  2DZY A;  3O1G A;  2NQG A;  3QJ3 A;  1KFU L;  3C9E A;  3I3T A;  1K3B B;  3HHA A;  3WXG A;  2NQI A;  4YYV A;  2R6N A;  3I06 A;  3PW3 A;  2DJG B;  1NL6 A;  2P0R A;  1GCB A;  2G8E A;  3N3G A;  3QSD A;  4Q8G A;  4BQV A;  3KWB X;  4BS5 A;  4KLB A;  2P7U A;  2IBI A;  2YJC A;  1EWL A;  2GHU A;  2PNS A;  1PIP A;  2G7Y A;  1KHP A;  1QDQ A;  1ME4 A;  3IMA A;  2XU3 A;  4P6E A;  2FQ9 A;  3P5U A;  2E01 A;  2B1N A;  3QT4 A;  2FTD A;  2ARY A;  1F2B A;  6PAD A;  3HHI A;  2BDL A;  3OVX A;  3WXE A;  4CDC B;  2XU4 A;  2F7D A;  1Q6K A;  3CBK A;  3P5X A;  2DC6 A;  2HHN A;  1PBH A;  4DMX A;  2FO5 A;  4G54 A;  3OIS A;  4YYS A;  1A6R A;  3P5V A;  2YJ2 A;  4MSX A;  1PPD A;  1AEC A;  2AVW A;  3GCB A;  4QRV A;  2YJ8 A;  4QRG A;  2BDZ A;  5CVO B;  2AS8 A;  1EWP A;  4FIP A;  2OZ2 A;  3IHP A;  3RVW A;  2PRE A;  4PAD A;  2R9F A;  4P6G A;  1ITO A;  4BS6 A;  1ICF A;  3TNX A;  1ME3 A;  1SNK A;  2FYE A;  5EGW A;  3CH2 X;  2DC7 A;  2JQF R;  2CB5 A;  1AYU A;  4OEL A;  2G8J A;  1F29 A;  3BPF A;  2Y6E A;  1KFX L;  1X9Y A;  3IV2 A;  4BPV A;  2FUD A;  3IUT A;  1THE A;  3LFY A;  2Y5B A;  1U9Q X;  2R9O A;  3KSE A;  2NQA A;  2NQD B;  3MTN A;  1TU6 A;  3PNR A;  3PDF A;  3M99 A;  5A24 A;  1MHW A;  4YYU A;  4QBB A;  4I04 A;  2AUX A;  1AYW A;  1ZCM A;  3KWZ A;  1QOL A;  3E1Z B;  4X6I A;  2IPP B;  3CH3 X;  4BSQ A;  4W4U A;  4AXL A;  4W5C A;  1NB5 A;  2R9C A;  3H89 A;  1ZIV A;  2HH5 A;  1BGO A;  2XU1 A;  1AU3 A;  2FRA A;  4FK5 A;  4OEM A;  2OP3 A;  1PAD A;  2B1M A;  4YV8 A;  3S3Q A;  1IWD A;  3F5V A;  4DMY A;  1U9V A;  1CPJ A;  2F1G A;  3ZUA A;  1BQI A;  4MZO A;  1M6D A;  3B79 A;  3N3K A;  1EF7 A;  1PPP A;  4YVA A;  3AI8 A;  3S3R A;  2JQG R;  1AU2 A;  3OF8 A;  3HWN A;  5CVM A;  1CQD A;  1VSN A;  1KHQ A;  4RY2 A;  9PAP A;  1NLJ A;  4MZS A;  1PCI A;  3BOW A;  4I05 A;  4FJC A;  2P86 A;  3RVV A;  3BC3 A;  3KW9 A;  4CDD B;  2DCA A;  1AIM A;  5JA7 A;  1Y4H A;  2HD5 A;  1PE6 A;  3NHE A;  4X6H A;  1YK8 A;  2YJ9 A;  1BY8 A;  4X6J A;  1CSB B;  1QMY A;  1F2A A;  2G6D A;  4AXM A;  1MEM A;  1Y08 A;  4XUI A;  1QXP A;  2VHS A;  4N8W A;  1JQP A;  1YT7 A;  4PP1 A;  1KXR A;  1U9X A;  1POP A;  1MS6 A;  2AUZ A;  3H8C A;  3K9M A;  4WA6 A;  1F2C A;  1AU4 A;  2E02 A;  1U5I A;  3PBH A;  5EF4 A;  2HXZ A;  3IEJ A;  2C0Y A;  1SP4 B;  4I07 A;  5CHV A;  2DCC A;  1PXV A;  1HUC B;  2DC9 A;  2WBF X;  1NQC A;  3U8E A;  1S4V A;  2E00 A;  1CTE A;  7PCK A;  2AU1 A;  3HD3 A;  1CV8 A;  4CDF B;  2DZZ A;  2ATO A;  4PP2 E;  8PCH A;  1PPN A;  1YAL A;  2E03 A;  2PAD A;  3K24 A;  2VHF A;  3V6C A;  2YJB A;  1AYV A;  2FRQ A;  3D6S A;  4QRX A;  3P5W A;  3KKU A;  4HWY A;  1GEC E;  3MHS A;  3V6E A;  1MEG A;  2AYO A;  3USV A;  4PI3 A;  1FH0 A;  1YVB A;  5PAD A;  3OF9 A;  5J94 A;  3K8U A;  1DEU A;  3F75 A;  1GMY A;  3WXF A;  1U9W A;  4CDE B;  3BWK A;  1MIR A;  4QH6 A;  3ERV A;  1TLO A;  2DC8 A;  2GFO A;  2R9N A;  1NPZ A;  1YK7 A;  4YYQ A;  5FPW A;  1CB5 A;  2R9M A;  2DJF B;  2XU5 A;  3N4C A;  2H7J A;  4N79 A;  1PPO A;  3KFQ A;  1CVZ A;  1BP4 A;  1EWO A;  1ATK A;  1GLO A;  4YYR A;  3RVX A;  1O0E A;  2OUL A;  2DCB A;  3OVZ A;  1MDW A;  2AYN A;  2DCD A;  5CHT A;  4CZW A;  4K7C A;  2AIM A;  5K16 A;  4YYW A;  1CS8 A;  1XKG A;  3MOR A;  4N4Z A;  3H7D A;  3H8B A;  3LXS A;  1AU0 A;  5CVN B;  2ACT A;  1CJL A;  1NB3 A;  4Q8H A;  3O0U A;  1VJV A;  3BPM A;  3IOQ A;  2PBH A;  5F02 A;  3H6S A;  4XR7 A;  1DF0 A;  2CIO A;  2FT2 A;  1TL9 A;  3KX1 A;  3MHH A;  2O6X A;  4ZUX U;  3CBJ A;  3BCN A;  5JH3 A;  3DF0 A;  1EWM A;  1STF E; 
#chains in the Genus database with same CATH topology
 4W5B A;  2DZY A;  3O1G A;  2NQG A;  3QJ3 A;  1KFU L;  3C9E A;  3I3T A;  1K3B B;  3HHA A;  3WXG A;  2NQI A;  4YYV A;  4D8B A;  2R6N A;  3MTV A;  3I06 A;  4D8I A;  3PW3 A;  2DJG B;  1NL6 A;  2P0R A;  1GCB A;  3B21 A;  2G8E A;  3N3G A;  3QSD A;  4Q8G A;  4BQV A;  3KWB X;  4BS5 A;  4BOP A;  4KLB A;  2P7U A;  2IBI A;  2YJC A;  1EWL A;  2GHU A;  2PNS A;  1PIP A;  2G7Y A;  1KHP A;  1QDQ A;  3BBA A;  1ME4 A;  3IMA A;  2XU3 A;  4P6E A;  2FQ9 A;  3P5U A;  2E01 A;  2B1N A;  3QT4 A;  3TMP A;  2FTD A;  2BTW B;  2ARY A;  1F2B A;  6PAD A;  3HHI A;  2BDL A;  3OVX A;  1UKF A;  3WXE A;  4CDC B;  2XU4 A;  2F7D A;  1Q6K A;  3CBK A;  3P5X A;  2DC6 A;  2HHN A;  1PBH A;  4DMX A;  2FO5 A;  4G54 A;  3OIS A;  4YYS A;  1A6R A;  5KO3 A;  3P5V A;  2YJ2 A;  4MSX A;  1PPD A;  1AEC A;  2AVW A;  4R3D A;  3GCB A;  4QRV A;  2JTC A;  2YJ8 A;  4QRG A;  2BDZ A;  4RNA A;  5CVO B;  2AS8 A;  4BOU A;  1EWP A;  4FIP A;  4BOQ A;  2OZ2 A;  3IHP A;  3RVW A;  2PRE A;  4PAD A;  2R9F A;  4P6G A;  1ITO A;  4BS6 A;  1YZB A;  2JRI A;  1ICF A;  3TNX A;  3PT2 A;  1ME3 A;  1SNK A;  3PHU A;  5E6J A;  2FYE A;  5EGW A;  3CH2 X;  2DC7 A;  4D8E A;  2JQF R;  2CB5 A;  1AYU A;  4OEL A;  2G8J A;  1F29 A;  3BPF A;  2Y6E A;  1KFX L;  1X9Y A;  3IV2 A;  4BPV A;  2FUD A;  3IUT A;  1THE A;  3LFY A;  4IUM A;  2Y5B A;  1U9Q X;  2R9O A;  3KSE A;  2NQA A;  2NQD B;  3MTN A;  1TU6 A;  3PNR A;  2J7Q C;  3PDF A;  4PT5 A;  3TRK A;  3M99 A;  5A24 A;  1MHW A;  4YYU A;  4QBB A;  4I04 A;  2AUX A;  2HWK A;  1AYW A;  1ZCM A;  3KWZ A;  3OQC A;  1QOL A;  3E1Z B;  3BB7 A;  4RKX A;  4X6I A;  2IPP B;  3CH3 X;  4BSQ A;  4W4U A;  4AXL A;  4W5C A;  1NB5 A;  2R9C A;  3H89 A;  1ZIV A;  2HH5 A;  1DKI A;  1BGO A;  2XU1 A;  1AU3 A;  2J7Q A;  2FRA A;  4HXD B;  4FK5 A;  4OEM A;  2OP3 A;  1PAD A;  2B1M A;  4YV8 A;  3S3Q A;  1IWD A;  3F5V A;  4DMY A;  4OVZ A;  1U9V A;  1CPJ A;  2F1G A;  3ZUA A;  1BQI A;  4MZO A;  1M6D A;  3B79 A;  3N3K A;  4A5U A;  1EF7 A;  1PPP A;  3W30 A;  3AI8 A;  4YVA A;  3S3R A;  2JQG R;  1AU2 A;  3OF8 A;  3HWN A;  5CVM A;  1CQD A;  1VSN A;  1KHQ A;  4MM3 B;  4RY2 A;  9PAP A;  1NLJ A;  4MZS A;  1PCI A;  3BOW A;  4I05 A;  4FJC A;  2P86 A;  3RVV A;  4XZX A;  3BC3 A;  3KW9 A;  4MI7 A;  4CDD B;  2DCA A;  1AIM A;  5JA7 A;  1Y4H A;  2HD5 A;  4BOZ A;  1PE6 A;  3NHE A;  4X6H A;  1YK8 A;  2YJ9 A;  3PSE A;  1BY8 A;  4X6J A;  1CSB B;  1QMY A;  1F2A A;  2G6D A;  4IP3 A;  4AXM A;  1MEM A;  1Y08 A;  4XUI A;  1QXP A;  2VHS A;  3PRP A;  4N8W A;  5JZE A;  4RF0 A;  1JQP A;  1YT7 A;  4PP1 A;  1KXR A;  1U9X A;  1POP A;  1MS6 A;  2AUZ A;  3O65 A;  3H8C A;  3K9M A;  4WA6 A;  1F2C A;  4P16 A;  1AU4 A;  2E02 A;  1U5I A;  3PBH A;  5EF4 A;  2HXZ A;  3IEJ A;  2DOS A;  2C0Y A;  3IFU A;  4REZ A;  1SP4 B;  4I07 A;  5CHV A;  2DCC A;  1PXV A;  1HUC B;  2DC9 A;  2WBF X;  1NQC A;  3U8E A;  1S4V A;  2E00 A;  4ZTB A;  1CTE A;  7PCK A;  2AU1 A;  2AGA A;  3RNV A;  3HD3 A;  1CV8 A;  4CDF B;  2DZZ A;  2ATO A;  4PP2 E;  8PCH A;  1PPN A;  1YAL A;  2E03 A;  2PAD A;  3K24 A;  4OVZ B;  2VHF A;  3V6C A;  2YJB A;  1AYV A;  2BU3 A;  2FRQ A;  4BOS A;  3D6S A;  4QRX A;  3P5W A;  3KKU A;  3PHW A;  1GEC E;  3MHS A;  4HWY A;  3V6E A;  3BY4 A;  1MEG A;  2AYO A;  3USV A;  4PI3 A;  1FH0 A;  1YVB A;  5PAD A;  3OF9 A;  5J94 A;  2FE8 A;  1DEU A;  3K8U A;  5EZS A;  2UZJ A;  3F75 A;  1GMY A;  3WXF A;  1U9W A;  4CDE B;  3BWK A;  4OW0 A;  1MIR A;  4QH6 A;  3ERV A;  1TLO A;  2DC8 A;  2GFO A;  2R9N A;  3MJ5 A;  1PVJ A;  1NPZ A;  2BTW A;  1YK7 A;  4YYQ A;  4WUR A;  5FPW A;  4RF1 A;  1CB5 A;  2R9M A;  2DJF B;  3MP2 A;  2XU5 A;  3E9S A;  3N4C A;  2H7J A;  4N79 A;  1PPO A;  3KFQ A;  1CVZ A;  5EZQ A;  1BP4 A;  1EWO A;  1ATK A;  1GLO A;  4YYR A;  3RVX A;  1O0E A;  2OUL A;  2DCB A;  3OVZ A;  1MDW A;  2AYN A;  3PRM A;  2DCD A;  5CHT A;  4CZW A;  4K7C A;  2AIM A;  5K16 A;  4YYW A;  1CS8 A;  2Z84 A;  1XKG A;  3MOR A;  4N4Z A;  3C0R A;  3H7D A;  3H8B A;  3LXS A;  1AU0 A;  3W31 A;  5CVN B;  2ACT A;  4GUA A;  1CJL A;  1NB3 A;  4Q8H A;  3O0U A;  1VJV A;  3BPM A;  3IOQ A;  2PBH A;  5F02 A;  3H6S A;  4XR7 A;  1DF0 A;  4M0W A;  2CIO A;  2FT2 A;  1TL9 A;  3KX1 A;  3PHX A;  3MHH A;  2O6X A;  3ZNH A;  4ZUX U;  3CBJ A;  3BCN A;  5JH3 A;  3DF0 A;  1EWM A;  1STF E; 
#chains in the Genus database with same CATH homology
 4W5B A;  2DZY A;  3O1G A;  2NQG A;  3QJ3 A;  1KFU L;  4BGF A;  3C9E A;  3I3T A;  1K3B B;  3HHA A;  3WXG A;  2NQI A;  4YYV A;  2R6N A;  3I06 A;  3PW3 A;  2DJG B;  1NL6 A;  2P0R A;  1GCB A;  2G8E A;  3N3G A;  3QSD A;  4Q8G A;  4BQV A;  3KWB X;  4BS5 A;  4KLB A;  1W6F A;  2IBI A;  2P7U A;  2YJC A;  1EWL A;  1W4T A;  2GHU A;  2PNS A;  1PIP A;  2G7Y A;  1KHP A;  1QDQ A;  1ME4 A;  3IMA A;  2XU3 A;  4P6E A;  2FQ9 A;  3P5U A;  2E01 A;  2B1N A;  3QT4 A;  2FTD A;  2ARY A;  1F2B A;  6PAD A;  3HHI A;  2BDL A;  3OVX A;  3WXE A;  4CDC B;  2XU4 A;  2F7D A;  1Q6K A;  3CBK A;  3P5X A;  2DC6 A;  2HHN A;  1PBH A;  4DMX A;  2FO5 A;  4G54 A;  3OIS A;  4YYS A;  1A6R A;  3P5V A;  2YJ2 A;  4MSX A;  1PPD A;  1AEC A;  2AVW A;  3GCB A;  4QRV A;  2YJ8 A;  4QRG A;  2BDZ A;  5CVO B;  2AS8 A;  1EWP A;  4FIP A;  2OZ2 A;  3IHP A;  3RVW A;  2PRE A;  4PAD A;  2R9F A;  4P6G A;  1ITO A;  4BS6 A;  1ICF A;  3TNX A;  1ME3 A;  1SNK A;  2FYE A;  5EGW A;  3CH2 X;  2DC7 A;  2JQF R;  2CB5 A;  1AYU A;  4OEL A;  2G8J A;  1F29 A;  3BPF A;  2Y6E A;  1KFX L;  1X9Y A;  3IV2 A;  4BPV A;  2FUD A;  3IUT A;  1THE A;  3LFY A;  2Y5B A;  1U9Q X;  2R9O A;  3KSE A;  2NQA A;  2NQD B;  3MTN A;  1TU6 A;  3PNR A;  3PDF A;  3M99 A;  5A24 A;  1MHW A;  4YYU A;  4QBB A;  4I04 A;  2AUX A;  1AYW A;  1ZCM A;  3KWZ A;  1QOL A;  3E1Z B;  4X6I A;  2IPP B;  3CH3 X;  4BSQ A;  4W4U A;  4AXL A;  4W5C A;  1NB5 A;  2R9C A;  3H89 A;  1ZIV A;  2HH5 A;  1BGO A;  2XU1 A;  1AU3 A;  2FRA A;  4FK5 A;  4OEM A;  2OP3 A;  1PAD A;  2B1M A;  4YV8 A;  3S3Q A;  1IWD A;  3F5V A;  4DMY A;  1U9V A;  1CPJ A;  2F1G A;  3ZUA A;  1BQI A;  4MZO A;  1M6D A;  3B79 A;  3N3K A;  1EF7 A;  1PPP A;  4YVA A;  3AI8 A;  4B55 A;  3S3R A;  2JQG R;  1AU2 A;  3OF8 A;  3HWN A;  5CVM A;  1CQD A;  1VSN A;  1KHQ A;  1GX3 A;  4RY2 A;  9PAP A;  1NLJ A;  4MZS A;  1PCI A;  3BOW A;  4I05 A;  4FJC A;  1E2T A;  2P86 A;  3RVV A;  3BC3 A;  3KW9 A;  4CDD B;  2DCA A;  1AIM A;  5JA7 A;  1Y4H A;  2HD5 A;  1PE6 A;  3NHE A;  4X6H A;  1YK8 A;  2YJ9 A;  4NV8 A;  1BY8 A;  4X6J A;  1CSB B;  2VFC A;  1QMY A;  1F2A A;  2G6D A;  4AXM A;  1MEM A;  1Y08 A;  4XUI A;  1QXP A;  2VHS A;  4N8W A;  1JQP A;  1YT7 A;  4PP1 A;  1KXR A;  1U9X A;  1POP A;  1MS6 A;  2AUZ A;  3H8C A;  3K9M A;  4WA6 A;  1F2C A;  1AU4 A;  2E02 A;  1U5I A;  3PBH A;  5EF4 A;  2HXZ A;  3IEJ A;  2C0Y A;  3LTW A;  1SP4 B;  4I07 A;  5CHV A;  2DCC A;  1PXV A;  1HUC B;  2DC9 A;  2WBF X;  1NQC A;  3U8E A;  1S4V A;  2E00 A;  1CTE A;  2BSZ A;  7PCK A;  2AU1 A;  3HD3 A;  1CV8 A;  4CDF B;  2DZZ A;  2ATO A;  4PP2 E;  8PCH A;  1PPN A;  1YAL A;  2E03 A;  2PAD A;  3K24 A;  2VHF A;  3V6C A;  2YJB A;  1AYV A;  2FRQ A;  3D6S A;  4QRX A;  3P5W A;  3KKU A;  4HWY A;  1GEC E;  3MHS A;  3V6E A;  1MEG A;  2AYO A;  3USV A;  4PI3 A;  1FH0 A;  1YVB A;  5PAD A;  3OF9 A;  5J94 A;  3K8U A;  1DEU A;  4C5P A;  3F75 A;  1GMY A;  3WXF A;  1U9W A;  4CDE B;  3BWK A;  1MIR A;  4QH6 A;  3ERV A;  4NV7 A;  1TLO A;  2DC8 A;  2GFO A;  2R9N A;  1NPZ A;  2VFB A;  1YK7 A;  4YYQ A;  5FPW A;  1CB5 A;  2R9M A;  2DJF B;  2XU5 A;  3N4C A;  2H7J A;  4N79 A;  1PPO A;  3KFQ A;  1CVZ A;  1BP4 A;  1EWO A;  1ATK A;  1GLO A;  4YYR A;  3RVX A;  1O0E A;  2OUL A;  2DCB A;  3OVZ A;  1MDW A;  2AYN A;  2DCD A;  5CHT A;  4CZW A;  4K7C A;  2AIM A;  5K16 A;  4YYW A;  1CS8 A;  1XKG A;  3MOR A;  4N4Z A;  3H7D A;  1W5R A;  3H8B A;  3LXS A;  1AU0 A;  5CVN B;  2ACT A;  4GUZ A;  1CJL A;  1NB3 A;  4Q8H A;  3O0U A;  1VJV A;  3BPM A;  3IOQ A;  2PBH A;  5F02 A;  3H6S A;  4XR7 A;  1DF0 A;  2CIO A;  2FT2 A;  1TL9 A;  3KX1 A;  3MHH A;  2O6X A;  4ZUX U;  3D9W A;  3CBJ A;  3BCN A;  5JH3 A;  3DF0 A;  1EWM A;  1STF E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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