2R9FA

Calpain 1 proteolytic core inactivated by zlak-3002, an alpha-ketoamide
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
322
structure length
322
Chain Sequence
NAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICNLT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Cocrystal structures of primed side-extending alpha-ketoamide inhibitors reveal novel calpain-inhibitor aromatic interactions.
pubmed doi rcsb
molecule tags Hydrolase
source organism Rattus norvegicus
molecule keywords Calpain-1 catalytic subunit
total genus 95
structure length 322
sequence length 322
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2007-09-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2r9fA02
3BPMA 4CDFB 1ITOA 1BP4A 1DF0A 4PP2E 1KXRA 5CVOB 3K8UA 1MEMA 4PI3A 1STFE 2R9FA 3C9EA 2XU1A 2P0RA 1CPJA 1AECA 3MHSA 2OULA 1CTEA 4QRGA 3RVVA 1SP4B 5JA7A 3HHAA 1PE6A 4QBBA 4CDEB 1AYUA 2XU3A 1IWDA 3E1ZB 2HHNA 1PPNA 3F75A 4BS5A 2GFOA 1TL9A 2NQAA 4CZWA 1AU0A 1KFUL 2FYEA 2FQ9A 2PNSA 2B1NA 3P5UA 1MHWA 4BSQA 2DZZA 1TU6A 1AYWA 1NPZA 1A6RA 1ME3A 3H7DA 1EWPA 3PDFA 1PBHA 2YJ8A 3KWBX 1QDQA 4AXMA 4W5BA 4CDDB 2DJGB 2G6DA 1CV8A 1CS8A 1PPPA 1F2BA 3P5VA 3CH3X 3OISA 2CIOA 2R9MA 3P5WA 3WXEA 2BDZA 3KX1A 4FK5A 2FTDA 1YK7A 2XU5A 3WXFA 1THEA 2Y5BA 1U9WA 2AIMA 3KFQA 1PCIA 2DC7A 2BDLA 4CDCB 1NL6A 3IOQA 4XR7A 1KHQA 2R9CA 2NQGA 2FO5A 3BC3A 3RVWA 2DCCA 5CVMA 3PBHA 2DCDA 5EGWA 3WXGA 1AYVA 2AU1A 3V6EA 2O6XA 3K24A 3KSEA 4QRVA 3IUTA 1ICFA 1CSBB 4Q8HA 1Y4HA 3I3TA 4WA6A 4RY2A 3ERVA 1YVBA 2DJFB 2FUDA 5CVNB 1YALA 2DC6A 3CH2X 2JQFR 3IHPA 1JQPA 1U9QX 1M6DA 3BPFA 1ZIVA 1MDWA 2E01A 4N79A 4X6HA 2P86A 4X6JA 3ZUAA 1KHPA 2R9OA 3HD3A 1NLJA 4OELA 1EF7A 5A24A 1CB5A 3CBKA 1Y08A 2XU4A 3NHEA 3HHIA 3QSDA 4BPVA 3DF0A 5CHTA 1GMYA 2YJ2A 3M99A 2DC8A 1U5IA 3N3GA 3OVXA 2AUZA 2HD5A 3LXSA 2F1GA 4N4ZA 4YV8A 3S3RA 4Q8GA 1FH0A 1U9VA 3N4CA 4I04A 4N8WA 8PCHA 1ME4A 5J94A 2PADA 4W4UA 2AYNA 2Y6EA 3S3QA 3I06A 1K3BB 3U8EA 2WBFX 2R9NA 2NQIA 2OZ2A 3B79A 3H6SA 2H7JA 1TLOA 2G7YA 1CVZA 3CBJA 1BGOA 4FJCA 4K7CA 1NB5A 1SNKA 9PAPA 1DEUA 5EF4A 4OEMA 4ZUXU 4I07A 3D6SA 4YVAA 1GLOA 1F29A 6PADA 2VHSA 5CHVA 3IMAA 3F5VA 2HH5A 1GCBA 5K16A 2DCAA 3MTNA 2R6NA 5F02A 2AYOA 3MHHA 1VJVA 4KLBA 1KFXL 2DC9A 1HUCB 4PADA 2PREA 2DCBA 1EWOA 1S4VA 2JQGR 4MZOA 2G8EA 1QXPA 1GECE 4YYQA 3BWKA 4G54A 1EWMA 3MORA 3K9MA 4FIPA 1CQDA 4HWYA 1QMYA 2P7UA 3QJ3A 4QRXA 1CJLA 2IBIA 2NQDB 1MS6A 4YYRA 5PADA 1VSNA 1AIMA 4P6GA 4MSXA 3H89A 1AU2A 7PCKA 1EWLA 1MIRA 2HXZA 3GCBA 1ZCMA 2AUXA 3KW9A 3IEJA 3O0UA 4YYSA 1U9XA 1YT7A 3OF9A 2F7DA 2E02A 2B1MA 3KWZA 1O0EA 1YK8A 2YJ9A 4I05A 4MZSA 3BOWA 2DZYA 3QT4A 2E00A 1PIPA 1BQIA 1PXVA 2ATOA 3USVA 1ATKA 2VHFA 2FRQA 3KKUA 1AU3A 2FRAA 3N3KA 2ACTA 1F2AA 3IV2A 2YJBA 1BY8A 4DMXA 4YYUA 5JH3A 1NQCA 3H8CA 2CB5A 3TNXA 2AS8A 3AI8A 2YJCA 4BS6A 3PNRA 4YYVA 1PPOA 1PPDA 1QOLA 4DMYA 2ARYA 3OVZA 3H8BA 4P6EA 2IPPB 3LFYA 1X9YA 4W5CA 4YYWA 2FT2A 3P5XA 1MEGA 1PADA 1NB3A 3BCNA 2AVWA 4XUIA 3PW3A 4QH6A 1AU4A 4X6IA 1F2CA 2C0YA 2G8JA 2PBHA 2OP3A 4AXLA 1XKGA 3O1GA 5FPWA 2E03A 4PP1A 3RVXA 3V6CA 3HWNA 3OF8A 2GHUA 4BQVA 1Q6KA 1POPA
chains in the Genus database with same CATH superfamily
3BPMA 4CDFB 1ITOA 1BP4A 1DF0A 4PP2E 1KXRA 5CVOB 3K8UA 1MEMA 4PI3A 1STFE 2R9FA 3C9EA 4D8BA 2XU1A 2P0RA 1CPJA 1AECA 4BOPA 2BTWB 3MHSA 4M0WA 2OULA 1CTEA 4QRGA 3RVVA 1SP4B 3IFUA 5JA7A 3HHAA 1PE6A 3PRMA 4QBBA 4CDEB 1YZBA 1AYUA 2XU3A 1IWDA 3E1ZB 2HHNA 1PPNA 3F75A 4BS5A 2GFOA 1TL9A 2NQAA 3TRKA 4CZWA 1AU0A 3PHWA 1KFUL 5EZQA 3W30A 2FYEA 2FQ9A 2PNSA 2B1NA 3P5UA 3PT2A 1MHWA 5KO3A 4BSQA 2DZZA 1TU6A 1AYWA 1NPZA 4D8IA 1A6RA 1ME3A 3H7DA 1EWPA 3PDFA 4IP3A 1PBHA 2YJ8A 3KWBX 1QDQA 4D8EA 4AXMA 4W5BA 4CDDB 2DJGB 2G6DA 1CV8A 1CS8A 1PPPA 1F2BA 4HXDB 3P5VA 3CH3X 3OISA 2CIOA 3BB7A 3BBAA 2R9MA 3P5WA 2BU3A 3WXEA 2BDZA 3KX1A 4FK5A 2FTDA 1YK7A 2XU5A 3WXFA 1THEA 2Y5BA 4MM3B 1U9WA 3BY4A 2AIMA 4P16A 3KFQA 1PCIA 2DC7A 2BDLA 4CDCB 1NL6A 3IOQA 4XR7A 3RNVA 1KHQA 2R9CA 2NQGA 2FO5A 3BC3A 3RVWA 2DCCA 5CVMA 5JZEA 3PBHA 2DCDA 5EGWA 3WXGA 1AYVA 4REZA 2AU1A 3V6EA 3KSEA 2O6XA 3K24A 4QRVA 3IUTA 1ICFA 1CSBB 4BOZA 4Q8HA 1Y4HA 3I3TA 4WA6A 4RY2A 3B21A 3C0RA 3ERVA 1YVBA 2DJFB 2FUDA 3MTVA 5CVNB 1YALA 2DC6A 3CH2X 2JQFR 3IHPA 1JQPA 1U9QX 1M6DA 3BPFA 1ZIVA 2AGAA 1MDWA 2E01A 4N79A 4X6HA 2P86A 4X6JA 3ZUAA 1KHPA 4ZTBA 4A5UA 2R9OA 3HD3A 1NLJA 4RF1A 2HWKA 2UZJA 4OELA 1EF7A 5A24A 1CB5A 3CBKA 1Y08A 2XU4A 3NHEA 3HHIA 3QSDA 4BPVA 3DF0A 5CHTA 1GMYA 4XZXA 2YJ2A 3M99A 2DC8A 1U5IA 3N3GA 3OVXA 2AUZA 2HD5A 3LXSA 2F1GA 4N4ZA 3W31A 4YV8A 3S3RA 4Q8GA 1FH0A 1DKIA 1U9VA 3N4CA 4I04A 4N8WA 8PCHA 1ME4A 5J94A 2PADA 4W4UA 2AYNA 4IUMA 2J7QC 2Y6EA 3S3QA 3I06A 1K3BB 3U8EA 2WBFX 2R9NA 2NQIA 2OZ2A 3B79A 3H6SA 2H7JA 1TLOA 2G7YA 4OW0A 1CVZA 4BOQA 3CBJA 1BGOA 4MI7A 4FJCA 4K7CA 1NB5A 1SNKA 9PAPA 1DEUA 5EF4A 4OEMA 4ZUXU 3MP2A 4I07A 4OVZB 3D6SA 4YVAA 1GLOA 1F29A 6PADA 2VHSA 5CHVA 3IMAA 3F5VA 2HH5A 1GCBA 5K16A 2DCAA 3MTNA 2R6NA 5F02A 3ZNHA 2AYOA 3MHHA 1VJVA 5E6JA 4KLBA 1KFXL 2DC9A 1HUCB 4PADA 2PREA 2DCBA 1EWOA 1S4VA 2JQGR 4MZOA 2G8EA 1QXPA 1GECE 4YYQA 3BWKA 4RKXA 4G54A 1EWMA 3MORA 3K9MA 4FIPA 4WURA 1CQDA 4HWYA 1QMYA 2P7UA 3E9SA 3QJ3A 4QRXA 1CJLA 2IBIA 2NQDB 1MS6A 4YYRA 5PADA 1VSNA 1AIMA 4P6GA 4MSXA 3H89A 1AU2A 7PCKA 1EWLA 2J7QA 2JRIA 2DOSA 1MIRA 1UKFA 2HXZA 3GCBA 3O65A 1ZCMA 2AUXA 5EZSA 3KW9A 3IEJA 3O0UA 4GUAA 4YYSA 1U9XA 1YT7A 3OF9A 2F7DA 4BOUA 2E02A 2B1MA 3KWZA 1O0EA 1YK8A 2YJ9A 4I05A 4MZSA 3BOWA 2DZYA 2BTWA 3OQCA 3QT4A 2E00A 1PIPA 4PT5A 1BQIA 1PXVA 2ATOA 3USVA 1ATKA 2VHFA 4RF0A 2FRQA 3KKUA 1AU3A 2FRAA 3N3KA 2ACTA 1F2AA 3IV2A 2YJBA 1BY8A 4DMXA 4YYUA 5JH3A 1NQCA 3H8CA 2CB5A 2FE8A 3TNXA 2AS8A 3AI8A 2YJCA 4BS6A 4RNAA 3PNRA 4YYVA 1PPOA 1PPDA 1QOLA 4DMYA 2ARYA 3OVZA 3H8BA 3PHXA 3MJ5A 4P6EA 2IPPB 3LFYA 1X9YA 3PRPA 1PVJA 4W5CA 4YYWA 2FT2A 3P5XA 1MEGA 1PADA 1NB3A 3BCNA 2AVWA 4XUIA 2Z84A 4BOSA 3PW3A 4QH6A 1AU4A 4X6IA 1F2CA 2C0YA 3TMPA 2G8JA 2PBHA 2OP3A 4AXLA 1XKGA 2JTCA 3O1GA 5FPWA 3PSEA 2E03A 4PP1A 3RVXA 3V6CA 3HWNA 3OF8A 2GHUA 4BQVA 1Q6KA 4OVZA 3PHUA 4R3DA 1POPA
chains in the Genus database with same CATH topology
3BPMA 4CDFB 2VFCA 1ITOA 1BP4A 1DF0A 4PP2E 1KXRA 5CVOB 1GX3A 3K8UA 1MEMA 4PI3A 1STFE 2R9FA 3C9EA 2XU1A 2P0RA 1CPJA 1AECA 3MHSA 2OULA 1CTEA 4QRGA 3RVVA 1SP4B 5JA7A 3HHAA 1PE6A 4QBBA 4CDEB 1AYUA 2XU3A 1IWDA 3E1ZB 2HHNA 1PPNA 3F75A 4BS5A 2GFOA 1TL9A 2NQAA 4CZWA 1AU0A 1KFUL 2FYEA 2FQ9A 2PNSA 2B1NA 3P5UA 1MHWA 4BSQA 2DZZA 1TU6A 1AYWA 1NPZA 1A6RA 1ME3A 3H7DA 1EWPA 3PDFA 1PBHA 2YJ8A 3KWBX 1QDQA 4AXMA 4W5BA 4CDDB 2DJGB 2G6DA 1CV8A 1CS8A 1PPPA 1F2BA 3P5VA 3CH3X 3OISA 2CIOA 2R9MA 3P5WA 3WXEA 2BDZA 3KX1A 4FK5A 2FTDA 1YK7A 2XU5A 3WXFA 1THEA 2Y5BA 1U9WA 3LTWA 2AIMA 3KFQA 1PCIA 2DC7A 2BDLA 4CDCB 1NL6A 3IOQA 4XR7A 1KHQA 2R9CA 2NQGA 2FO5A 3BC3A 4NV8A 3RVWA 2DCCA 5CVMA 3PBHA 2DCDA 5EGWA 3WXGA 1AYVA 2AU1A 3V6EA 2O6XA 3K24A 3KSEA 4QRVA 3IUTA 1ICFA 1CSBB 4Q8HA 1Y4HA 3I3TA 4WA6A 4RY2A 3ERVA 1YVBA 1W6FA 2DJFB 2FUDA 3D9WA 5CVNB 1YALA 2DC6A 3CH2X 2JQFR 3IHPA 1JQPA 1U9QX 1M6DA 3BPFA 1ZIVA 1MDWA 2E01A 4N79A 4X6HA 2P86A 2VFBA 4X6JA 3ZUAA 1KHPA 2R9OA 3HD3A 1NLJA 4OELA 1EF7A 5A24A 1CB5A 3CBKA 1Y08A 2XU4A 3NHEA 3HHIA 3QSDA 4BPVA 3DF0A 5CHTA 1GMYA 2YJ2A 3M99A 2DC8A 1U5IA 3N3GA 3OVXA 2AUZA 2HD5A 3LXSA 2F1GA 4N4ZA 4YV8A 3S3RA 4Q8GA 1FH0A 1U9VA 3N4CA 4I04A 4N8WA 8PCHA 1ME4A 5J94A 2PADA 4W4UA 2AYNA 2Y6EA 3S3QA 3I06A 1K3BB 3U8EA 2WBFX 2R9NA 2NQIA 2OZ2A 3B79A 3H6SA 2H7JA 1TLOA 2G7YA 1CVZA 3CBJA 1BGOA 4FJCA 4K7CA 1NB5A 1SNKA 1W5RA 9PAPA 1DEUA 5EF4A 4OEMA 4ZUXU 4I07A 3D6SA 4YVAA 1GLOA 1F29A 6PADA 2VHSA 5CHVA 3IMAA 3F5VA 2HH5A 1GCBA 5K16A 2DCAA 3MTNA 2R6NA 5F02A 2AYOA 3MHHA 1VJVA 1E2TA 4KLBA 1KFXL 2DC9A 1HUCB 4PADA 2PREA 2DCBA 1EWOA 1S4VA 2JQGR 4MZOA 2G8EA 1QXPA 1GECE 4YYQA 3BWKA 4G54A 1EWMA 3MORA 3K9MA 4FIPA 1CQDA 4HWYA 1QMYA 2P7UA 3QJ3A 4QRXA 1CJLA 2IBIA 2NQDB 1MS6A 4YYRA 5PADA 1VSNA 1AIMA 4P6GA 4MSXA 3H89A 1AU2A 7PCKA 1EWLA 1MIRA 2HXZA 3GCBA 4C5PA 1ZCMA 2AUXA 3KW9A 3IEJA 3O0UA 4YYSA 1U9XA 1YT7A 3OF9A 2F7DA 2E02A 2B1MA 3KWZA 1O0EA 1YK8A 2YJ9A 4I05A 4MZSA 3BOWA 2DZYA 4BGFA 3QT4A 2E00A 1PIPA 1BQIA 1PXVA 4NV7A 2ATOA 3USVA 1ATKA 2VHFA 2FRQA 3KKUA 1AU3A 2FRAA 3N3KA 2ACTA 1F2AA 3IV2A 2YJBA 1BY8A 4DMXA 4YYUA 5JH3A 1NQCA 3H8CA 2CB5A 3TNXA 2BSZA 2AS8A 3AI8A 2YJCA 4BS6A 3PNRA 4YYVA 1PPOA 1PPDA 1QOLA 4DMYA 2ARYA 4B55A 3OVZA 3H8BA 4P6EA 2IPPB 3LFYA 1X9YA 4W5CA 4YYWA 2FT2A 3P5XA 1MEGA 1PADA 1NB3A 3BCNA 2AVWA 4XUIA 3PW3A 4QH6A 1AU4A 4X6IA 1F2CA 2C0YA 2G8JA 2PBHA 2OP3A 4AXLA 1XKGA 3O1GA 5FPWA 2E03A 4PP1A 3RVXA 4GUZA 3V6CA 3HWNA 3OF8A 2GHUA 4BQVA 1Q6KA 1W4TA 1POPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BPM A;  4CDF B;  1ITO A;  1BP4 A;  1DF0 A;  4PP2 E;  1KXR A;  5CVO B;  3K8U A;  1MEM A;  4PI3 A;  1STF E;  2R9F A;  3C9E A;  2XU1 A;  2P0R A;  1CPJ A;  1AEC A;  3MHS A;  2OUL A;  1CTE A;  4QRG A;  3RVV A;  1SP4 B;  5JA7 A;  3HHA A;  1PE6 A;  4QBB A;  4CDE B;  1AYU A;  2XU3 A;  1IWD A;  3E1Z B;  2HHN A;  1PPN A;  3F75 A;  4BS5 A;  2GFO A;  1TL9 A;  2NQA A;  4CZW A;  1AU0 A;  1KFU L;  2FYE A;  2FQ9 A;  2PNS A;  2B1N A;  3P5U A;  1MHW A;  4BSQ A;  2DZZ A;  1TU6 A;  1AYW A;  1NPZ A;  1A6R A;  1ME3 A;  3H7D A;  1EWP A;  3PDF A;  1PBH A;  2YJ8 A;  3KWB X;  1QDQ A;  4AXM A;  4W5B A;  4CDD B;  2DJG B;  2G6D A;  1CV8 A;  1CS8 A;  1PPP A;  1F2B A;  3P5V A;  3CH3 X;  3OIS A;  2CIO A;  2R9M A;  3P5W A;  3WXE A;  2BDZ A;  3KX1 A;  4FK5 A;  2FTD A;  1YK7 A;  2XU5 A;  3WXF A;  1THE A;  2Y5B A;  1U9W A;  2AIM A;  3KFQ A;  1PCI A;  2DC7 A;  2BDL A;  4CDC B;  1NL6 A;  3IOQ A;  4XR7 A;  1KHQ A;  2R9C A;  2NQG A;  2FO5 A;  3BC3 A;  3RVW A;  2DCC A;  5CVM A;  3PBH A;  2DCD A;  5EGW A;  3WXG A;  1AYV A;  2AU1 A;  3V6E A;  2O6X A;  3K24 A;  3KSE A;  4QRV A;  3IUT A;  1ICF A;  1CSB B;  4Q8H A;  1Y4H A;  3I3T A;  4WA6 A;  4RY2 A;  3ERV A;  1YVB A;  2DJF B;  2FUD A;  5CVN B;  1YAL A;  2DC6 A;  3CH2 X;  2JQF R;  3IHP A;  1JQP A;  1U9Q X;  1M6D A;  3BPF A;  1ZIV A;  1MDW A;  2E01 A;  4N79 A;  4X6H A;  2P86 A;  4X6J A;  3ZUA A;  1KHP A;  2R9O A;  3HD3 A;  1NLJ A;  4OEL A;  1EF7 A;  5A24 A;  1CB5 A;  3CBK A;  1Y08 A;  2XU4 A;  3NHE A;  3HHI A;  3QSD A;  4BPV A;  3DF0 A;  5CHT A;  1GMY A;  2YJ2 A;  3M99 A;  2DC8 A;  1U5I A;  3N3G A;  3OVX A;  2AUZ A;  2HD5 A;  3LXS A;  2F1G A;  4N4Z A;  4YV8 A;  3S3R A;  4Q8G A;  1FH0 A;  1U9V A;  3N4C A;  4I04 A;  4N8W A;  8PCH A;  1ME4 A;  5J94 A;  2PAD A;  4W4U A;  2AYN A;  2Y6E A;  3S3Q A;  3I06 A;  1K3B B;  3U8E A;  2WBF X;  2R9N A;  2NQI A;  2OZ2 A;  3B79 A;  3H6S A;  2H7J A;  1TLO A;  2G7Y A;  1CVZ A;  3CBJ A;  1BGO A;  4FJC A;  4K7C A;  1NB5 A;  1SNK A;  9PAP A;  1DEU A;  5EF4 A;  4OEM A;  4ZUX U;  4I07 A;  3D6S A;  4YVA A;  1GLO A;  1F29 A;  6PAD A;  2VHS A;  5CHV A;  3IMA A;  3F5V A;  2HH5 A;  1GCB A;  5K16 A;  2DCA A;  3MTN A;  2R6N A;  5F02 A;  2AYO A;  3MHH A;  1VJV A;  4KLB A;  1KFX L;  2DC9 A;  1HUC B;  4PAD A;  2PRE A;  2DCB A;  1EWO A;  1S4V A;  2JQG R;  4MZO A;  2G8E A;  1QXP A;  1GEC E;  4YYQ A;  3BWK A;  4G54 A;  1EWM A;  3MOR A;  3K9M A;  4FIP A;  1CQD A;  4HWY A;  1QMY A;  2P7U A;  3QJ3 A;  4QRX A;  1CJL A;  2IBI A;  2NQD B;  1MS6 A;  4YYR A;  5PAD A;  1VSN A;  1AIM A;  4P6G A;  4MSX A;  3H89 A;  1AU2 A;  7PCK A;  1EWL A;  1MIR A;  2HXZ A;  3GCB A;  1ZCM A;  2AUX A;  3KW9 A;  3IEJ A;  3O0U A;  4YYS A;  1U9X A;  1YT7 A;  3OF9 A;  2F7D A;  2E02 A;  2B1M A;  3KWZ A;  1O0E A;  1YK8 A;  2YJ9 A;  4I05 A;  4MZS A;  3BOW A;  2DZY A;  3QT4 A;  2E00 A;  1PIP A;  1BQI A;  1PXV A;  2ATO A;  3USV A;  1ATK A;  2VHF A;  2FRQ A;  3KKU A;  1AU3 A;  2FRA A;  3N3K A;  2ACT A;  1F2A A;  3IV2 A;  2YJB A;  1BY8 A;  4DMX A;  4YYU A;  5JH3 A;  1NQC A;  3H8C A;  2CB5 A;  3TNX A;  2AS8 A;  3AI8 A;  2YJC A;  4BS6 A;  3PNR A;  4YYV A;  1PPO A;  1PPD A;  1QOL A;  4DMY A;  2ARY A;  3OVZ A;  3H8B A;  4P6E A;  2IPP B;  3LFY A;  1X9Y A;  4W5C A;  4YYW A;  2FT2 A;  3P5X A;  1MEG A;  1PAD A;  1NB3 A;  3BCN A;  2AVW A;  4XUI A;  3PW3 A;  4QH6 A;  1AU4 A;  4X6I A;  1F2C A;  2C0Y A;  2G8J A;  2PBH A;  2OP3 A;  4AXL A;  1XKG A;  3O1G A;  5FPW A;  2E03 A;  4PP1 A;  3RVX A;  3V6C A;  3HWN A;  3OF8 A;  2GHU A;  4BQV A;  1Q6K A;  1POP A; 
#chains in the Genus database with same CATH topology
 3BPM A;  4CDF B;  1ITO A;  1BP4 A;  1DF0 A;  4PP2 E;  1KXR A;  5CVO B;  3K8U A;  1MEM A;  4PI3 A;  1STF E;  2R9F A;  3C9E A;  4D8B A;  2XU1 A;  2P0R A;  1CPJ A;  1AEC A;  4BOP A;  2BTW B;  3MHS A;  4M0W A;  2OUL A;  1CTE A;  4QRG A;  3RVV A;  1SP4 B;  3IFU A;  5JA7 A;  3HHA A;  1PE6 A;  3PRM A;  4QBB A;  4CDE B;  1YZB A;  1AYU A;  2XU3 A;  1IWD A;  3E1Z B;  2HHN A;  1PPN A;  3F75 A;  4BS5 A;  2GFO A;  1TL9 A;  2NQA A;  3TRK A;  4CZW A;  1AU0 A;  3PHW A;  1KFU L;  5EZQ A;  3W30 A;  2FYE A;  2FQ9 A;  2PNS A;  2B1N A;  3P5U A;  3PT2 A;  1MHW A;  5KO3 A;  4BSQ A;  2DZZ A;  1TU6 A;  1AYW A;  1NPZ A;  4D8I A;  1A6R A;  1ME3 A;  3H7D A;  1EWP A;  3PDF A;  4IP3 A;  1PBH A;  2YJ8 A;  3KWB X;  1QDQ A;  4D8E A;  4AXM A;  4W5B A;  4CDD B;  2DJG B;  2G6D A;  1CV8 A;  1CS8 A;  1PPP A;  1F2B A;  4HXD B;  3P5V A;  3CH3 X;  3OIS A;  2CIO A;  3BB7 A;  3BBA A;  2R9M A;  3P5W A;  2BU3 A;  3WXE A;  2BDZ A;  3KX1 A;  4FK5 A;  2FTD A;  1YK7 A;  2XU5 A;  3WXF A;  1THE A;  2Y5B A;  4MM3 B;  1U9W A;  3BY4 A;  2AIM A;  4P16 A;  3KFQ A;  1PCI A;  2DC7 A;  2BDL A;  4CDC B;  1NL6 A;  3IOQ A;  4XR7 A;  3RNV A;  1KHQ A;  2R9C A;  2NQG A;  2FO5 A;  3BC3 A;  3RVW A;  2DCC A;  5CVM A;  5JZE A;  3PBH A;  2DCD A;  5EGW A;  3WXG A;  1AYV A;  4REZ A;  2AU1 A;  3V6E A;  3KSE A;  2O6X A;  3K24 A;  4QRV A;  3IUT A;  1ICF A;  1CSB B;  4BOZ A;  4Q8H A;  1Y4H A;  3I3T A;  4WA6 A;  4RY2 A;  3B21 A;  3C0R A;  3ERV A;  1YVB A;  2DJF B;  2FUD A;  3MTV A;  5CVN B;  1YAL A;  2DC6 A;  3CH2 X;  2JQF R;  3IHP A;  1JQP A;  1U9Q X;  1M6D A;  3BPF A;  1ZIV A;  2AGA A;  1MDW A;  2E01 A;  4N79 A;  4X6H A;  2P86 A;  4X6J A;  3ZUA A;  1KHP A;  4ZTB A;  4A5U A;  2R9O A;  3HD3 A;  1NLJ A;  4RF1 A;  2HWK A;  2UZJ A;  4OEL A;  1EF7 A;  5A24 A;  1CB5 A;  3CBK A;  1Y08 A;  2XU4 A;  3NHE A;  3HHI A;  3QSD A;  4BPV A;  3DF0 A;  5CHT A;  1GMY A;  4XZX A;  2YJ2 A;  3M99 A;  2DC8 A;  1U5I A;  3N3G A;  3OVX A;  2AUZ A;  2HD5 A;  3LXS A;  2F1G A;  4N4Z A;  3W31 A;  4YV8 A;  3S3R A;  4Q8G A;  1FH0 A;  1DKI A;  1U9V A;  3N4C A;  4I04 A;  4N8W A;  8PCH A;  1ME4 A;  5J94 A;  2PAD A;  4W4U A;  2AYN A;  4IUM A;  2J7Q C;  2Y6E A;  3S3Q A;  3I06 A;  1K3B B;  3U8E A;  2WBF X;  2R9N A;  2NQI A;  2OZ2 A;  3B79 A;  3H6S A;  2H7J A;  1TLO A;  2G7Y A;  4OW0 A;  1CVZ A;  4BOQ A;  3CBJ A;  1BGO A;  4MI7 A;  4FJC A;  4K7C A;  1NB5 A;  1SNK A;  9PAP A;  1DEU A;  5EF4 A;  4OEM A;  4ZUX U;  3MP2 A;  4I07 A;  4OVZ B;  3D6S A;  4YVA A;  1GLO A;  1F29 A;  6PAD A;  2VHS A;  5CHV A;  3IMA A;  3F5V A;  2HH5 A;  1GCB A;  5K16 A;  2DCA A;  3MTN A;  2R6N A;  5F02 A;  3ZNH A;  2AYO A;  3MHH A;  1VJV A;  5E6J A;  4KLB A;  1KFX L;  2DC9 A;  1HUC B;  4PAD A;  2PRE A;  2DCB A;  1EWO A;  1S4V A;  2JQG R;  4MZO A;  2G8E A;  1QXP A;  1GEC E;  4YYQ A;  3BWK A;  4RKX A;  4G54 A;  1EWM A;  3MOR A;  3K9M A;  4FIP A;  4WUR A;  1CQD A;  4HWY A;  1QMY A;  2P7U A;  3E9S A;  3QJ3 A;  4QRX A;  1CJL A;  2IBI A;  2NQD B;  1MS6 A;  4YYR A;  5PAD A;  1VSN A;  1AIM A;  4P6G A;  4MSX A;  3H89 A;  1AU2 A;  7PCK A;  1EWL A;  2J7Q A;  2JRI A;  2DOS A;  1MIR A;  1UKF A;  2HXZ A;  3GCB A;  3O65 A;  1ZCM A;  2AUX A;  5EZS A;  3KW9 A;  3IEJ A;  3O0U A;  4GUA A;  4YYS A;  1U9X A;  1YT7 A;  3OF9 A;  2F7D A;  4BOU A;  2E02 A;  2B1M A;  3KWZ A;  1O0E A;  1YK8 A;  2YJ9 A;  4I05 A;  4MZS A;  3BOW A;  2DZY A;  2BTW A;  3OQC A;  3QT4 A;  2E00 A;  1PIP A;  4PT5 A;  1BQI A;  1PXV A;  2ATO A;  3USV A;  1ATK A;  2VHF A;  4RF0 A;  2FRQ A;  3KKU A;  1AU3 A;  2FRA A;  3N3K A;  2ACT A;  1F2A A;  3IV2 A;  2YJB A;  1BY8 A;  4DMX A;  4YYU A;  5JH3 A;  1NQC A;  3H8C A;  2CB5 A;  2FE8 A;  3TNX A;  2AS8 A;  3AI8 A;  2YJC A;  4BS6 A;  4RNA A;  3PNR A;  4YYV A;  1PPO A;  1PPD A;  1QOL A;  4DMY A;  2ARY A;  3OVZ A;  3H8B A;  3PHX A;  3MJ5 A;  4P6E A;  2IPP B;  3LFY A;  1X9Y A;  3PRP A;  1PVJ A;  4W5C A;  4YYW A;  2FT2 A;  3P5X A;  1MEG A;  1PAD A;  1NB3 A;  3BCN A;  2AVW A;  4XUI A;  2Z84 A;  4BOS A;  3PW3 A;  4QH6 A;  1AU4 A;  4X6I A;  1F2C A;  2C0Y A;  3TMP A;  2G8J A;  2PBH A;  2OP3 A;  4AXL A;  1XKG A;  2JTC A;  3O1G A;  5FPW A;  3PSE A;  2E03 A;  4PP1 A;  3RVX A;  3V6C A;  3HWN A;  3OF8 A;  2GHU A;  4BQV A;  1Q6K A;  4OVZ A;  3PHU A;  4R3D A;  1POP A; 
#chains in the Genus database with same CATH homology
 3BPM A;  4CDF B;  2VFC A;  1ITO A;  1BP4 A;  1DF0 A;  4PP2 E;  1KXR A;  5CVO B;  1GX3 A;  3K8U A;  1MEM A;  4PI3 A;  1STF E;  2R9F A;  3C9E A;  2XU1 A;  2P0R A;  1CPJ A;  1AEC A;  3MHS A;  2OUL A;  1CTE A;  4QRG A;  3RVV A;  1SP4 B;  5JA7 A;  3HHA A;  1PE6 A;  4QBB A;  4CDE B;  1AYU A;  2XU3 A;  1IWD A;  3E1Z B;  2HHN A;  1PPN A;  3F75 A;  4BS5 A;  2GFO A;  1TL9 A;  2NQA A;  4CZW A;  1AU0 A;  1KFU L;  2FYE A;  2FQ9 A;  2PNS A;  2B1N A;  3P5U A;  1MHW A;  4BSQ A;  2DZZ A;  1TU6 A;  1AYW A;  1NPZ A;  1A6R A;  1ME3 A;  3H7D A;  1EWP A;  3PDF A;  1PBH A;  2YJ8 A;  3KWB X;  1QDQ A;  4AXM A;  4W5B A;  4CDD B;  2DJG B;  2G6D A;  1CV8 A;  1CS8 A;  1PPP A;  1F2B A;  3P5V A;  3CH3 X;  3OIS A;  2CIO A;  2R9M A;  3P5W A;  3WXE A;  2BDZ A;  3KX1 A;  4FK5 A;  2FTD A;  1YK7 A;  2XU5 A;  3WXF A;  1THE A;  2Y5B A;  1U9W A;  3LTW A;  2AIM A;  3KFQ A;  1PCI A;  2DC7 A;  2BDL A;  4CDC B;  1NL6 A;  3IOQ A;  4XR7 A;  1KHQ A;  2R9C A;  2NQG A;  2FO5 A;  3BC3 A;  4NV8 A;  3RVW A;  2DCC A;  5CVM A;  3PBH A;  2DCD A;  5EGW A;  3WXG A;  1AYV A;  2AU1 A;  3V6E A;  2O6X A;  3K24 A;  3KSE A;  4QRV A;  3IUT A;  1ICF A;  1CSB B;  4Q8H A;  1Y4H A;  3I3T A;  4WA6 A;  4RY2 A;  3ERV A;  1YVB A;  1W6F A;  2DJF B;  2FUD A;  3D9W A;  5CVN B;  1YAL A;  2DC6 A;  3CH2 X;  2JQF R;  3IHP A;  1JQP A;  1U9Q X;  1M6D A;  3BPF A;  1ZIV A;  1MDW A;  2E01 A;  4N79 A;  4X6H A;  2P86 A;  2VFB A;  4X6J A;  3ZUA A;  1KHP A;  2R9O A;  3HD3 A;  1NLJ A;  4OEL A;  1EF7 A;  5A24 A;  1CB5 A;  3CBK A;  1Y08 A;  2XU4 A;  3NHE A;  3HHI A;  3QSD A;  4BPV A;  3DF0 A;  5CHT A;  1GMY A;  2YJ2 A;  3M99 A;  2DC8 A;  1U5I A;  3N3G A;  3OVX A;  2AUZ A;  2HD5 A;  3LXS A;  2F1G A;  4N4Z A;  4YV8 A;  3S3R A;  4Q8G A;  1FH0 A;  1U9V A;  3N4C A;  4I04 A;  4N8W A;  8PCH A;  1ME4 A;  5J94 A;  2PAD A;  4W4U A;  2AYN A;  2Y6E A;  3S3Q A;  3I06 A;  1K3B B;  3U8E A;  2WBF X;  2R9N A;  2NQI A;  2OZ2 A;  3B79 A;  3H6S A;  2H7J A;  1TLO A;  2G7Y A;  1CVZ A;  3CBJ A;  1BGO A;  4FJC A;  4K7C A;  1NB5 A;  1SNK A;  1W5R A;  9PAP A;  1DEU A;  5EF4 A;  4OEM A;  4ZUX U;  4I07 A;  3D6S A;  4YVA A;  1GLO A;  1F29 A;  6PAD A;  2VHS A;  5CHV A;  3IMA A;  3F5V A;  2HH5 A;  1GCB A;  5K16 A;  2DCA A;  3MTN A;  2R6N A;  5F02 A;  2AYO A;  3MHH A;  1VJV A;  1E2T A;  4KLB A;  1KFX L;  2DC9 A;  1HUC B;  4PAD A;  2PRE A;  2DCB A;  1EWO A;  1S4V A;  2JQG R;  4MZO A;  2G8E A;  1QXP A;  1GEC E;  4YYQ A;  3BWK A;  4G54 A;  1EWM A;  3MOR A;  3K9M A;  4FIP A;  1CQD A;  4HWY A;  1QMY A;  2P7U A;  3QJ3 A;  4QRX A;  1CJL A;  2IBI A;  2NQD B;  1MS6 A;  4YYR A;  5PAD A;  1VSN A;  1AIM A;  4P6G A;  4MSX A;  3H89 A;  1AU2 A;  7PCK A;  1EWL A;  1MIR A;  2HXZ A;  3GCB A;  4C5P A;  1ZCM A;  2AUX A;  3KW9 A;  3IEJ A;  3O0U A;  4YYS A;  1U9X A;  1YT7 A;  3OF9 A;  2F7D A;  2E02 A;  2B1M A;  3KWZ A;  1O0E A;  1YK8 A;  2YJ9 A;  4I05 A;  4MZS A;  3BOW A;  2DZY A;  4BGF A;  3QT4 A;  2E00 A;  1PIP A;  1BQI A;  1PXV A;  4NV7 A;  2ATO A;  3USV A;  1ATK A;  2VHF A;  2FRQ A;  3KKU A;  1AU3 A;  2FRA A;  3N3K A;  2ACT A;  1F2A A;  3IV2 A;  2YJB A;  1BY8 A;  4DMX A;  4YYU A;  5JH3 A;  1NQC A;  3H8C A;  2CB5 A;  3TNX A;  2BSZ A;  2AS8 A;  3AI8 A;  2YJC A;  4BS6 A;  3PNR A;  4YYV A;  1PPO A;  1PPD A;  1QOL A;  4DMY A;  2ARY A;  4B55 A;  3OVZ A;  3H8B A;  4P6E A;  2IPP B;  3LFY A;  1X9Y A;  4W5C A;  4YYW A;  2FT2 A;  3P5X A;  1MEG A;  1PAD A;  1NB3 A;  3BCN A;  2AVW A;  4XUI A;  3PW3 A;  4QH6 A;  1AU4 A;  4X6I A;  1F2C A;  2C0Y A;  2G8J A;  2PBH A;  2OP3 A;  4AXL A;  1XKG A;  3O1G A;  5FPW A;  2E03 A;  4PP1 A;  3RVX A;  4GUZ A;  3V6C A;  3HWN A;  3OF8 A;  2GHU A;  4BQV A;  1Q6K A;  1W4T A;  1POP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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