2O6XA

Crystal structure of procathepsin l1 from fasciola hepatica
Total Genus 115
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
310
structure length
306
Chain Sequence
NDDLWHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMTFEEFKAKYLTEMSRASDILSHGVPYEAVPDKIDWRESGYVTEVKDQGNCGSGWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSRPWGNNGCGGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGFYTVHSGSEVELKNLVGAEGPAAVAVDVESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGLSWGERGYIRMVRNRGNMCGIASLASLPMVARFP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and functional relationships in the virulence-associated cathepsin L proteases of the parasitic liver fluke, Fasciola hepatica.
pubmed doi rcsb
source organism Fasciola hepatica
molecule tags Hydrolase
molecule keywords Secreted cathepsin L 1
total genus 115
structure length 306
sequence length 310
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2006-12-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
A PF08246 Inhibitor_I29 Cathepsin propeptide inhibitor domain (I29)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2o6xA00
3OF9A 1F2CA 1EWOA 3KSEA 1MIRA 1MHWA 3U8EA 2P86A 2HD5A 4XUIA 2DJGB 4YYUA 2BDLA 1EWMA 3KFQA 4XR7A 2R6NA 1HUCB 2C0YA 2P7UA 3K24A 3BPFA 1GECE 2YJ9A 3AI8A 1CTEA 1AU3A 1KXRA 2PBHA 4HWYA 1PPOA 1PXVA 2F7DA 2FQ9A 1AECA 1U9WA 4BS6A 4YYWA 3WXEA 3LXSA 3OVZA 3MTNA 5CVOB 1AYUA 2E01A 3QJ3A 5EGWA 1CSBB 2HHNA 3RVXA 1POPA 1MS6A 1PCIA 3KKUA 1PPDA 1DEUA 2YJCA 3OVXA 2XU1A 1CPJA 5J94A 7PCKA 4CZWA 1BP4A 3BCNA 1ME4A 2OZ2A 3N3KA 2NQDB 3NHEA 4YYVA 1Y08A 1GLOA 2Y5BA 2DCBA 1BY8A 1PADA 5EF4A 1F29A 1KFUL 3KX1A 3LFYA 2IBIA 1QXPA 5CVMA 2FTDA 1YVBA 1DF0A 1A6RA 4QBBA 2HXZA 1MDWA 2NQAA 4Q8HA 1AYVA 2CIOA 3QSDA 2O6XA 2DC9A 4YYRA 3HD3A 4MZSA 1THEA 2VHSA 3PDFA 1PPPA 2BDZA 3WXGA 2DC8A 2R9CA 1U9XA 3IUTA 2GFOA 3P5XA 1AIMA 4FK5A 5CHVA 4FJCA 5CHTA 2F1GA 2DZZA 1TLOA 4CDDB 1F2AA 1VSNA 3H8BA 1YK8A 1SP4B 4WA6A 4DMYA 2PREA 2GHUA 1IWDA 2WBFX 2ATOA 1NQCA 2YJBA 3H7DA 3IV2A 1CV8A 3BOWA 3BC3A 2AUZA 2H7JA 2P0RA 4CDCB 2DZYA 3V6CA 4FIPA 4YV8A 3BPMA 3PNRA 3H8CA 4OEMA 1PE6A 4QRGA 2XU5A 2NQIA 2FT2A 2E00A 2Y6EA 1MEGA 1QDQA 2FYEA 3HWNA 2E02A 4PP1A 2G6DA 4BS5A 3PW3A 1ATKA 4N4ZA 3IHPA 4BPVA 2CB5A 2FO5A 2JQFR 1QMYA 3H89A 3K9MA 1Q6KA 6PADA 2XU3A 4I07A 1XKGA 2FRQA 1AU2A 1NB5A 1CQDA 3F5VA 1U5IA 1S4VA 5JH3A 3CBKA 5JA7A 3MHSA 1PPNA 1ITOA 3ERVA 1U9VA 1MEMA 2FRAA 3RVWA 4CDFB 5FPWA 4X6HA 2OULA 4CDEB 2ARYA 1EWLA 8PCHA 4PP2E 1ME3A 1KHPA 4BSQA 1FH0A 2YJ8A 2DJFB 1CB5A 2AIMA 2JQGR 2HH5A 1X9YA 1Y4HA 1VJVA 4MSXA 3D6SA 2B1MA 1SNKA 4P6EA 4W4UA 3HHIA 4W5CA 3DF0A 5K16A 3S3QA 4YYQA 1M6DA 3S3RA 1NPZA 3P5VA 5PADA 4KLBA 2VHFA 4X6IA 1KHQA 1YALA 2AYOA 2PNSA 3ZUAA 2NQGA 1KFXL 3CH3X 2R9MA 3N4CA 3KWZA 4RY2A 3KW9A 2R9FA 3I3TA 3C9EA 1PIPA 1JQPA 3F75A 3WXFA 1PBHA 4G54A 5CVNB 2AUXA 1NLJA 3M99A 1ICFA 3K8UA 2AU1A 3RVVA 1BGOA 1K3BB 3HHAA 3O0UA 1CS8A 2G7YA 2YJ2A 3BWKA 1AU4A 3IMAA 4ZUXU 3MHHA 1AYWA 2AYNA 1YT7A 3GCBA 3USVA 4N8WA 4AXLA 1NL6A 3OISA 3PBHA 1YK7A 4N79A 3CH2X 1F2BA 2DC6A 3IOQA 1NB3A 3CBJA 2PADA 4PI3A 2XU4A 3B79A 5A24A 1ZCMA 3H6SA 4PADA 1U9QX 1ZIVA 4I04A 2DCAA 3V6EA 2AS8A 1AU0A 1GMYA 1TL9A 4Q8GA 1O0EA 4AXMA 4QRVA 4MZOA 1GCBA 2R9NA 2ACTA 4X6JA 3QT4A 1CVZA 3P5WA 1QOLA 2IPPB 4K7CA 1BQIA 4YVAA 4W5BA 4I05A 2DCCA 1EWPA 5F02A 2E03A 2FUDA 3O1GA 1CJLA 3MORA 4OELA 2AVWA 3I06A 3IEJA 2G8JA 3KWBX 4DMXA 2B1NA 2OP3A 3E1ZB 1STFE 1EF7A 3N3GA 1TU6A 4P6GA 2G8EA 3TNXA 2DC7A 4QRXA 9PAPA 2DCDA 2R9OA 3OF8A 4YYSA 3P5UA 4BQVA 4QH6A
chains in the Genus database with same CATH superfamily
3OF9A 4PT5A 1F2CA 1EWOA 3KSEA 4RKXA 1MIRA 1MHWA 3U8EA 2P86A 2HD5A 3PHUA 2DJGB 3PRMA 4XUIA 4YYUA 2BDLA 1EWMA 3KFQA 4XR7A 2R6NA 1HUCB 2C0YA 2P7UA 3K24A 3BPFA 1GECE 2YJ9A 3AI8A 1CTEA 1AU3A 1KXRA 2PBHA 1DKIA 4HWYA 1PPOA 1PXVA 4BOSA 5E6JA 3RNVA 2F7DA 2FQ9A 2JTCA 1AECA 1U9WA 4BS6A 4YYWA 3WXEA 3LXSA 1PVJA 3OVZA 3MTNA 4REZA 5CVOB 1AYUA 2E01A 3QJ3A 3BB7A 5EGWA 1CSBB 2HHNA 3RVXA 1POPA 1MS6A 1PCIA 3KKUA 1PPDA 1DEUA 3B21A 2YJCA 3OVXA 2XU1A 1CPJA 4OVZB 5J94A 7PCKA 4CZWA 1BP4A 3BCNA 1ME4A 4D8EA 2OZ2A 3N3KA 2NQDB 3NHEA 4YYVA 1Y08A 4IP3A 1GLOA 2Y5BA 2DCBA 1BY8A 1PADA 5EF4A 1F29A 1KFUL 3KX1A 3LFYA 2IBIA 1QXPA 5CVMA 2FTDA 1YVBA 1DF0A 4D8BA 1A6RA 4QBBA 2HXZA 2UZJA 1MDWA 2NQAA 4Q8HA 1AYVA 2CIOA 3QSDA 2O6XA 2Z84A 2DC9A 4YYRA 3HD3A 4MZSA 1THEA 3OQCA 4D8IA 4XZXA 2VHSA 3O65A 3PDFA 1PPPA 2BDZA 3WXGA 2DC8A 4RNAA 2R9CA 1U9XA 3IUTA 2GFOA 3P5XA 3PSEA 1AIMA 4FK5A 5CHVA 4FJCA 5CHTA 2F1GA 2DZZA 1TLOA 4CDDB 1F2AA 1VSNA 3H8BA 4R3DA 2JRIA 1YK8A 1SP4B 4WA6A 5EZSA 4DMYA 2PREA 2GHUA 1IWDA 2WBFX 4BOPA 3W30A 2ATOA 1NQCA 2YJBA 3H7DA 3IV2A 3MJ5A 1CV8A 3BOWA 3BC3A 2AUZA 2H7JA 2P0RA 4CDCB 2DZYA 3V6CA 4FIPA 4YV8A 3BPMA 3PNRA 3H8CA 4OEMA 1PE6A 4QRGA 2XU5A 2NQIA 2FT2A 2E00A 2Y6EA 1MEGA 1QDQA 2FYEA 5KO3A 4P16A 3HWNA 2E02A 4PP1A 2G6DA 4OW0A 4BS5A 3PW3A 4BOUA 1ATKA 3PHXA 4N4ZA 3IHPA 4BPVA 4BOQA 2CB5A 2FO5A 4GUAA 2JQFR 1QMYA 3H89A 3K9MA 5JZEA 1Q6KA 4HXDB 6PADA 2XU3A 4I07A 1XKGA 2FRQA 1AU2A 1NB5A 1CQDA 3F5VA 5EZQA 1U5IA 1S4VA 1UKFA 5JH3A 3CBKA 3IFUA 5JA7A 3MHSA 1PPNA 1ITOA 3ERVA 1U9VA 1MEMA 2FRAA 3RVWA 3PRPA 3ZNHA 4CDFB 5FPWA 2DOSA 4X6HA 2OULA 2BTWB 4CDEB 2ARYA 1EWLA 3MTVA 8PCHA 4PP2E 1ME3A 1KHPA 4BSQA 1FH0A 2YJ8A 2DJFB 1CB5A 2AIMA 2JQGR 2HH5A 1X9YA 1Y4HA 4M0WA 1VJVA 4MM3B 4MSXA 2J7QC 3D6SA 4MI7A 2B1MA 1SNKA 4P6EA 3PT2A 4W4UA 3HHIA 4W5CA 3DF0A 5K16A 3S3QA 4YYQA 1M6DA 3S3RA 1NPZA 3P5VA 5PADA 4KLBA 2VHFA 3C0RA 4X6IA 1KHQA 1YALA 2AYOA 2PNSA 3ZUAA 2NQGA 1KFXL 3CH3X 2R9MA 3N4CA 3KWZA 4RY2A 3KW9A 2R9FA 3I3TA 3C9EA 1PIPA 1JQPA 3TRKA 3F75A 2AGAA 3WXFA 1PBHA 4G54A 5CVNB 2AUXA 1NLJA 3M99A 1ICFA 3K8UA 3TMPA 2AU1A 1BGOA 3RVVA 3W31A 1K3BB 2BTWA 3HHAA 3O0UA 1CS8A 2G7YA 3MP2A 2YJ2A 3BWKA 1AU4A 2BU3A 3IMAA 4ZUXU 3MHHA 1AYWA 2AYNA 1YT7A 3GCBA 3USVA 4N8WA 4AXLA 4RF1A 1NL6A 3OISA 3PBHA 1YK7A 4N79A 3CH2X 1F2BA 4A5UA 2DC6A 3IOQA 1NB3A 3CBJA 2PADA 4PI3A 4RF0A 2XU4A 3B79A 5A24A 1ZCMA 3H6SA 4PADA 1U9QX 1ZIVA 4I04A 2DCAA 4IUMA 3V6EA 2AS8A 4WURA 1AU0A 1GMYA 1TL9A 4Q8GA 1O0EA 4AXMA 4QRVA 3BBAA 4ZTBA 4MZOA 1GCBA 2HWKA 2R9NA 2ACTA 4X6JA 3QT4A 1CVZA 3P5WA 1QOLA 2IPPB 4K7CA 1BQIA 1YZBA 4YVAA 4W5BA 4I05A 2DCCA 1EWPA 5F02A 2E03A 2FUDA 3O1GA 3E9SA 1CJLA 3BY4A 3MORA 4OELA 2FE8A 2AVWA 3I06A 3IEJA 2G8JA 3KWBX 4DMXA 2B1NA 2OP3A 3E1ZB 1STFE 1EF7A 3N3GA 1TU6A 2J7QA 4P6GA 2G8EA 3TNXA 2DC7A 3PHWA 4QRXA 9PAPA 4OVZA 4BOZA 2DCDA 2R9OA 3OF8A 4YYSA 3P5UA 4BQVA 4QH6A
chains in the Genus database with same CATH topology
3OF9A 1F2CA 1EWOA 3KSEA 1MIRA 1MHWA 1E2TA 3U8EA 2P86A 2HD5A 4XUIA 2DJGB 4YYUA 2BDLA 1EWMA 3KFQA 4XR7A 2R6NA 1HUCB 2C0YA 2P7UA 3K24A 3BPFA 1GECE 2YJ9A 3AI8A 1CTEA 1AU3A 1KXRA 2PBHA 4HWYA 1PPOA 1PXVA 2F7DA 2FQ9A 1AECA 1U9WA 4BS6A 4YYWA 3WXEA 3LXSA 3OVZA 3MTNA 5CVOB 1AYUA 2E01A 3LTWA 3QJ3A 5EGWA 1CSBB 2HHNA 3RVXA 1POPA 1MS6A 1PCIA 3KKUA 1PPDA 1DEUA 2YJCA 3OVXA 4C5PA 2XU1A 1CPJA 5J94A 7PCKA 4CZWA 1BP4A 3BCNA 1ME4A 2OZ2A 3N3KA 2NQDB 3NHEA 4YYVA 1Y08A 1GLOA 2Y5BA 2DCBA 1BY8A 1PADA 5EF4A 1F29A 1KFUL 3KX1A 3LFYA 2IBIA 1QXPA 5CVMA 2FTDA 1YVBA 1DF0A 1A6RA 4QBBA 2HXZA 1MDWA 2NQAA 4Q8HA 1AYVA 2CIOA 3QSDA 2O6XA 2DC9A 4NV7A 4YYRA 3HD3A 4MZSA 1THEA 2VHSA 3PDFA 1PPPA 2BDZA 3WXGA 2DC8A 2R9CA 1U9XA 3IUTA 2GFOA 3P5XA 1AIMA 4FK5A 5CHVA 4FJCA 5CHTA 2F1GA 2VFBA 2DZZA 1TLOA 4CDDB 1W5RA 1F2AA 1VSNA 3H8BA 1YK8A 1SP4B 4WA6A 4DMYA 2PREA 2GHUA 1IWDA 2WBFX 2ATOA 1NQCA 2YJBA 3H7DA 3IV2A 1CV8A 3BOWA 3BC3A 2AUZA 2H7JA 2P0RA 4CDCB 2DZYA 3V6CA 4FIPA 4YV8A 3BPMA 3PNRA 3H8CA 4OEMA 1PE6A 4QRGA 2XU5A 4B55A 2NQIA 2FT2A 2E00A 2Y6EA 1MEGA 1QDQA 2FYEA 3HWNA 2E02A 4PP1A 2G6DA 4BS5A 3PW3A 1ATKA 4N4ZA 3IHPA 4BPVA 2CB5A 2FO5A 2JQFR 1QMYA 3H89A 3K9MA 1Q6KA 6PADA 2XU3A 4I07A 1XKGA 2FRQA 1AU2A 1NB5A 1CQDA 3F5VA 1U5IA 4GUZA 1S4VA 5JH3A 3CBKA 5JA7A 3MHSA 1PPNA 1ITOA 3ERVA 1U9VA 1MEMA 2FRAA 3RVWA 4CDFB 5FPWA 4X6HA 1W6FA 2OULA 4CDEB 2ARYA 1EWLA 8PCHA 4PP2E 1ME3A 1KHPA 4BSQA 1FH0A 2YJ8A 2DJFB 1CB5A 2AIMA 2JQGR 2HH5A 1X9YA 1Y4HA 1VJVA 4MSXA 4NV8A 3D6SA 2B1MA 1SNKA 4P6EA 4W4UA 3HHIA 4W5CA 3DF0A 5K16A 3S3QA 4YYQA 1M6DA 3S3RA 1NPZA 3P5VA 5PADA 1GX3A 4KLBA 2VHFA 4X6IA 1KHQA 1YALA 2AYOA 2PNSA 3ZUAA 2NQGA 2BSZA 3D9WA 1KFXL 3CH3X 2R9MA 3N4CA 3KWZA 4RY2A 3KW9A 2R9FA 3I3TA 3C9EA 1PIPA 1JQPA 3F75A 3WXFA 1PBHA 4G54A 5CVNB 2AUXA 1NLJA 3M99A 1ICFA 3K8UA 2AU1A 1BGOA 3RVVA 1K3BB 3HHAA 3O0UA 1CS8A 2G7YA 2YJ2A 3BWKA 1AU4A 3IMAA 4ZUXU 3MHHA 1AYWA 2AYNA 1YT7A 3GCBA 3USVA 4N8WA 4AXLA 1NL6A 3OISA 3PBHA 2VFCA 1YK7A 4N79A 3CH2X 1F2BA 2DC6A 3IOQA 1NB3A 3CBJA 2PADA 4PI3A 2XU4A 3B79A 5A24A 1ZCMA 3H6SA 4PADA 1U9QX 1ZIVA 4I04A 2DCAA 3V6EA 2AS8A 1AU0A 1GMYA 1TL9A 4Q8GA 1O0EA 4AXMA 4QRVA 4MZOA 1GCBA 2R9NA 2ACTA 4X6JA 3QT4A 1CVZA 3P5WA 1QOLA 2IPPB 4K7CA 1BQIA 4YVAA 4W5BA 4I05A 2DCCA 1EWPA 5F02A 2E03A 2FUDA 3O1GA 1CJLA 1W4TA 3MORA 4OELA 2AVWA 3I06A 3IEJA 2G8JA 3KWBX 4DMXA 2B1NA 2OP3A 3E1ZB 1STFE 1EF7A 3N3GA 1TU6A 4P6GA 2G8EA 3TNXA 2DC7A 4QRXA 9PAPA 2DCDA 2R9OA 3OF8A 4YYSA 4BGFA 3P5UA 4BQVA 4QH6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OF9 A;  1F2C A;  1EWO A;  3KSE A;  1MIR A;  1MHW A;  3U8E A;  2P86 A;  2HD5 A;  4XUI A;  2DJG B;  4YYU A;  2BDL A;  1EWM A;  3KFQ A;  4XR7 A;  2R6N A;  1HUC B;  2C0Y A;  2P7U A;  3K24 A;  3BPF A;  1GEC E;  2YJ9 A;  3AI8 A;  1CTE A;  1AU3 A;  1KXR A;  2PBH A;  4HWY A;  1PPO A;  1PXV A;  2F7D A;  2FQ9 A;  1AEC A;  1U9W A;  4BS6 A;  4YYW A;  3WXE A;  3LXS A;  3OVZ A;  3MTN A;  5CVO B;  1AYU A;  2E01 A;  3QJ3 A;  5EGW A;  1CSB B;  2HHN A;  3RVX A;  1POP A;  1MS6 A;  1PCI A;  3KKU A;  1PPD A;  1DEU A;  2YJC A;  3OVX A;  2XU1 A;  1CPJ A;  5J94 A;  7PCK A;  4CZW A;  1BP4 A;  3BCN A;  1ME4 A;  2OZ2 A;  3N3K A;  2NQD B;  3NHE A;  4YYV A;  1Y08 A;  1GLO A;  2Y5B A;  2DCB A;  1BY8 A;  1PAD A;  5EF4 A;  1F29 A;  1KFU L;  3KX1 A;  3LFY A;  2IBI A;  1QXP A;  5CVM A;  2FTD A;  1YVB A;  1DF0 A;  1A6R A;  4QBB A;  2HXZ A;  1MDW A;  2NQA A;  4Q8H A;  1AYV A;  2CIO A;  3QSD A;  2O6X A;  2DC9 A;  4YYR A;  3HD3 A;  4MZS A;  1THE A;  2VHS A;  3PDF A;  1PPP A;  2BDZ A;  3WXG A;  2DC8 A;  2R9C A;  1U9X A;  3IUT A;  2GFO A;  3P5X A;  1AIM A;  4FK5 A;  5CHV A;  4FJC A;  5CHT A;  2F1G A;  2DZZ A;  1TLO A;  4CDD B;  1F2A A;  1VSN A;  3H8B A;  1YK8 A;  1SP4 B;  4WA6 A;  4DMY A;  2PRE A;  2GHU A;  1IWD A;  2WBF X;  2ATO A;  1NQC A;  2YJB A;  3H7D A;  3IV2 A;  1CV8 A;  3BOW A;  3BC3 A;  2AUZ A;  2H7J A;  2P0R A;  4CDC B;  2DZY A;  3V6C A;  4FIP A;  4YV8 A;  3BPM A;  3PNR A;  3H8C A;  4OEM A;  1PE6 A;  4QRG A;  2XU5 A;  2NQI A;  2FT2 A;  2E00 A;  2Y6E A;  1MEG A;  1QDQ A;  2FYE A;  3HWN A;  2E02 A;  4PP1 A;  2G6D A;  4BS5 A;  3PW3 A;  1ATK A;  4N4Z A;  3IHP A;  4BPV A;  2CB5 A;  2FO5 A;  2JQF R;  1QMY A;  3H89 A;  3K9M A;  1Q6K A;  6PAD A;  2XU3 A;  4I07 A;  1XKG A;  2FRQ A;  1AU2 A;  1NB5 A;  1CQD A;  3F5V A;  1U5I A;  1S4V A;  5JH3 A;  3CBK A;  5JA7 A;  3MHS A;  1PPN A;  1ITO A;  3ERV A;  1U9V A;  1MEM A;  2FRA A;  3RVW A;  4CDF B;  5FPW A;  4X6H A;  2OUL A;  4CDE B;  2ARY A;  1EWL A;  8PCH A;  4PP2 E;  1ME3 A;  1KHP A;  4BSQ A;  1FH0 A;  2YJ8 A;  2DJF B;  1CB5 A;  2AIM A;  2JQG R;  2HH5 A;  1X9Y A;  1Y4H A;  1VJV A;  4MSX A;  3D6S A;  2B1M A;  1SNK A;  4P6E A;  4W4U A;  3HHI A;  4W5C A;  3DF0 A;  5K16 A;  3S3Q A;  4YYQ A;  1M6D A;  3S3R A;  1NPZ A;  3P5V A;  5PAD A;  4KLB A;  2VHF A;  4X6I A;  1KHQ A;  1YAL A;  2AYO A;  2PNS A;  3ZUA A;  2NQG A;  1KFX L;  3CH3 X;  2R9M A;  3N4C A;  3KWZ A;  4RY2 A;  3KW9 A;  2R9F A;  3I3T A;  3C9E A;  1PIP A;  1JQP A;  3F75 A;  3WXF A;  1PBH A;  4G54 A;  5CVN B;  2AUX A;  1NLJ A;  3M99 A;  1ICF A;  3K8U A;  2AU1 A;  3RVV A;  1BGO A;  1K3B B;  3HHA A;  3O0U A;  1CS8 A;  2G7Y A;  2YJ2 A;  3BWK A;  1AU4 A;  3IMA A;  4ZUX U;  3MHH A;  1AYW A;  2AYN A;  1YT7 A;  3GCB A;  3USV A;  4N8W A;  4AXL A;  1NL6 A;  3OIS A;  3PBH A;  1YK7 A;  4N79 A;  3CH2 X;  1F2B A;  2DC6 A;  3IOQ A;  1NB3 A;  3CBJ A;  2PAD A;  4PI3 A;  2XU4 A;  3B79 A;  5A24 A;  1ZCM A;  3H6S A;  4PAD A;  1U9Q X;  1ZIV A;  4I04 A;  2DCA A;  3V6E A;  2AS8 A;  1AU0 A;  1GMY A;  1TL9 A;  4Q8G A;  1O0E A;  4AXM A;  4QRV A;  4MZO A;  1GCB A;  2R9N A;  2ACT A;  4X6J A;  3QT4 A;  1CVZ A;  3P5W A;  1QOL A;  2IPP B;  4K7C A;  1BQI A;  4YVA A;  4W5B A;  4I05 A;  2DCC A;  1EWP A;  5F02 A;  2E03 A;  2FUD A;  3O1G A;  1CJL A;  3MOR A;  4OEL A;  2AVW A;  3I06 A;  3IEJ A;  2G8J A;  3KWB X;  4DMX A;  2B1N A;  2OP3 A;  3E1Z B;  1STF E;  1EF7 A;  3N3G A;  1TU6 A;  4P6G A;  2G8E A;  3TNX A;  2DC7 A;  4QRX A;  9PAP A;  2DCD A;  2R9O A;  3OF8 A;  4YYS A;  3P5U A;  4BQV A;  4QH6 A; 
#chains in the Genus database with same CATH topology
 3OF9 A;  4PT5 A;  1F2C A;  1EWO A;  3KSE A;  4RKX A;  1MIR A;  1MHW A;  3U8E A;  2P86 A;  2HD5 A;  3PHU A;  2DJG B;  3PRM A;  4XUI A;  4YYU A;  2BDL A;  1EWM A;  3KFQ A;  4XR7 A;  2R6N A;  1HUC B;  2C0Y A;  2P7U A;  3K24 A;  3BPF A;  1GEC E;  2YJ9 A;  3AI8 A;  1CTE A;  1AU3 A;  1KXR A;  2PBH A;  1DKI A;  4HWY A;  1PPO A;  1PXV A;  4BOS A;  5E6J A;  3RNV A;  2F7D A;  2FQ9 A;  2JTC A;  1AEC A;  1U9W A;  4BS6 A;  4YYW A;  3WXE A;  3LXS A;  1PVJ A;  3OVZ A;  3MTN A;  4REZ A;  5CVO B;  1AYU A;  2E01 A;  3QJ3 A;  3BB7 A;  5EGW A;  1CSB B;  2HHN A;  3RVX A;  1POP A;  1MS6 A;  1PCI A;  3KKU A;  1PPD A;  1DEU A;  3B21 A;  2YJC A;  3OVX A;  2XU1 A;  1CPJ A;  4OVZ B;  5J94 A;  7PCK A;  4CZW A;  1BP4 A;  3BCN A;  1ME4 A;  4D8E A;  2OZ2 A;  3N3K A;  2NQD B;  3NHE A;  4YYV A;  1Y08 A;  4IP3 A;  1GLO A;  2Y5B A;  2DCB A;  1BY8 A;  1PAD A;  5EF4 A;  1F29 A;  1KFU L;  3KX1 A;  3LFY A;  2IBI A;  1QXP A;  5CVM A;  2FTD A;  1YVB A;  1DF0 A;  4D8B A;  1A6R A;  4QBB A;  2HXZ A;  2UZJ A;  1MDW A;  2NQA A;  4Q8H A;  1AYV A;  2CIO A;  3QSD A;  2O6X A;  2Z84 A;  2DC9 A;  4YYR A;  3HD3 A;  4MZS A;  1THE A;  3OQC A;  4D8I A;  4XZX A;  2VHS A;  3O65 A;  3PDF A;  1PPP A;  2BDZ A;  3WXG A;  2DC8 A;  4RNA A;  2R9C A;  1U9X A;  3IUT A;  2GFO A;  3P5X A;  3PSE A;  1AIM A;  4FK5 A;  5CHV A;  4FJC A;  5CHT A;  2F1G A;  2DZZ A;  1TLO A;  4CDD B;  1F2A A;  1VSN A;  3H8B A;  4R3D A;  2JRI A;  1YK8 A;  1SP4 B;  4WA6 A;  5EZS A;  4DMY A;  2PRE A;  2GHU A;  1IWD A;  2WBF X;  4BOP A;  3W30 A;  2ATO A;  1NQC A;  2YJB A;  3H7D A;  3IV2 A;  3MJ5 A;  1CV8 A;  3BOW A;  3BC3 A;  2AUZ A;  2H7J A;  2P0R A;  4CDC B;  2DZY A;  3V6C A;  4FIP A;  4YV8 A;  3BPM A;  3PNR A;  3H8C A;  4OEM A;  1PE6 A;  4QRG A;  2XU5 A;  2NQI A;  2FT2 A;  2E00 A;  2Y6E A;  1MEG A;  1QDQ A;  2FYE A;  5KO3 A;  4P16 A;  3HWN A;  2E02 A;  4PP1 A;  2G6D A;  4OW0 A;  4BS5 A;  3PW3 A;  4BOU A;  1ATK A;  3PHX A;  4N4Z A;  3IHP A;  4BPV A;  4BOQ A;  2CB5 A;  2FO5 A;  4GUA A;  2JQF R;  1QMY A;  3H89 A;  3K9M A;  5JZE A;  1Q6K A;  4HXD B;  6PAD A;  2XU3 A;  4I07 A;  1XKG A;  2FRQ A;  1AU2 A;  1NB5 A;  1CQD A;  3F5V A;  5EZQ A;  1U5I A;  1S4V A;  1UKF A;  5JH3 A;  3CBK A;  3IFU A;  5JA7 A;  3MHS A;  1PPN A;  1ITO A;  3ERV A;  1U9V A;  1MEM A;  2FRA A;  3RVW A;  3PRP A;  3ZNH A;  4CDF B;  5FPW A;  2DOS A;  4X6H A;  2OUL A;  2BTW B;  4CDE B;  2ARY A;  1EWL A;  3MTV A;  8PCH A;  4PP2 E;  1ME3 A;  1KHP A;  4BSQ A;  1FH0 A;  2YJ8 A;  2DJF B;  1CB5 A;  2AIM A;  2JQG R;  2HH5 A;  1X9Y A;  1Y4H A;  4M0W A;  1VJV A;  4MM3 B;  4MSX A;  2J7Q C;  3D6S A;  4MI7 A;  2B1M A;  1SNK A;  4P6E A;  3PT2 A;  4W4U A;  3HHI A;  4W5C A;  3DF0 A;  5K16 A;  3S3Q A;  4YYQ A;  1M6D A;  3S3R A;  1NPZ A;  3P5V A;  5PAD A;  4KLB A;  2VHF A;  3C0R A;  4X6I A;  1KHQ A;  1YAL A;  2AYO A;  2PNS A;  3ZUA A;  2NQG A;  1KFX L;  3CH3 X;  2R9M A;  3N4C A;  3KWZ A;  4RY2 A;  3KW9 A;  2R9F A;  3I3T A;  3C9E A;  1PIP A;  1JQP A;  3TRK A;  3F75 A;  2AGA A;  3WXF A;  1PBH A;  4G54 A;  5CVN B;  2AUX A;  1NLJ A;  3M99 A;  1ICF A;  3K8U A;  3TMP A;  2AU1 A;  1BGO A;  3RVV A;  3W31 A;  1K3B B;  2BTW A;  3HHA A;  3O0U A;  1CS8 A;  2G7Y A;  3MP2 A;  2YJ2 A;  3BWK A;  1AU4 A;  2BU3 A;  3IMA A;  4ZUX U;  3MHH A;  1AYW A;  2AYN A;  1YT7 A;  3GCB A;  3USV A;  4N8W A;  4AXL A;  4RF1 A;  1NL6 A;  3OIS A;  3PBH A;  1YK7 A;  4N79 A;  3CH2 X;  1F2B A;  4A5U A;  2DC6 A;  3IOQ A;  1NB3 A;  3CBJ A;  2PAD A;  4PI3 A;  4RF0 A;  2XU4 A;  3B79 A;  5A24 A;  1ZCM A;  3H6S A;  4PAD A;  1U9Q X;  1ZIV A;  4I04 A;  2DCA A;  4IUM A;  3V6E A;  2AS8 A;  4WUR A;  1AU0 A;  1GMY A;  1TL9 A;  4Q8G A;  1O0E A;  4AXM A;  4QRV A;  3BBA A;  4ZTB A;  4MZO A;  1GCB A;  2HWK A;  2R9N A;  2ACT A;  4X6J A;  3QT4 A;  1CVZ A;  3P5W A;  1QOL A;  2IPP B;  4K7C A;  1BQI A;  1YZB A;  4YVA A;  4W5B A;  4I05 A;  2DCC A;  1EWP A;  5F02 A;  2E03 A;  2FUD A;  3O1G A;  3E9S A;  1CJL A;  3BY4 A;  3MOR A;  4OEL A;  2FE8 A;  2AVW A;  3I06 A;  3IEJ A;  2G8J A;  3KWB X;  4DMX A;  2B1N A;  2OP3 A;  3E1Z B;  1STF E;  1EF7 A;  3N3G A;  1TU6 A;  2J7Q A;  4P6G A;  2G8E A;  3TNX A;  2DC7 A;  3PHW A;  4QRX A;  9PAP A;  4OVZ A;  4BOZ A;  2DCD A;  2R9O A;  3OF8 A;  4YYS A;  3P5U A;  4BQV A;  4QH6 A; 
#chains in the Genus database with same CATH homology
 3OF9 A;  1F2C A;  1EWO A;  3KSE A;  1MIR A;  1MHW A;  1E2T A;  3U8E A;  2P86 A;  2HD5 A;  4XUI A;  2DJG B;  4YYU A;  2BDL A;  1EWM A;  3KFQ A;  4XR7 A;  2R6N A;  1HUC B;  2C0Y A;  2P7U A;  3K24 A;  3BPF A;  1GEC E;  2YJ9 A;  3AI8 A;  1CTE A;  1AU3 A;  1KXR A;  2PBH A;  4HWY A;  1PPO A;  1PXV A;  2F7D A;  2FQ9 A;  1AEC A;  1U9W A;  4BS6 A;  4YYW A;  3WXE A;  3LXS A;  3OVZ A;  3MTN A;  5CVO B;  1AYU A;  2E01 A;  3LTW A;  3QJ3 A;  5EGW A;  1CSB B;  2HHN A;  3RVX A;  1POP A;  1MS6 A;  1PCI A;  3KKU A;  1PPD A;  1DEU A;  2YJC A;  3OVX A;  4C5P A;  2XU1 A;  1CPJ A;  5J94 A;  7PCK A;  4CZW A;  1BP4 A;  3BCN A;  1ME4 A;  2OZ2 A;  3N3K A;  2NQD B;  3NHE A;  4YYV A;  1Y08 A;  1GLO A;  2Y5B A;  2DCB A;  1BY8 A;  1PAD A;  5EF4 A;  1F29 A;  1KFU L;  3KX1 A;  3LFY A;  2IBI A;  1QXP A;  5CVM A;  2FTD A;  1YVB A;  1DF0 A;  1A6R A;  4QBB A;  2HXZ A;  1MDW A;  2NQA A;  4Q8H A;  1AYV A;  2CIO A;  3QSD A;  2O6X A;  2DC9 A;  4NV7 A;  4YYR A;  3HD3 A;  4MZS A;  1THE A;  2VHS A;  3PDF A;  1PPP A;  2BDZ A;  3WXG A;  2DC8 A;  2R9C A;  1U9X A;  3IUT A;  2GFO A;  3P5X A;  1AIM A;  4FK5 A;  5CHV A;  4FJC A;  5CHT A;  2F1G A;  2VFB A;  2DZZ A;  1TLO A;  4CDD B;  1W5R A;  1F2A A;  1VSN A;  3H8B A;  1YK8 A;  1SP4 B;  4WA6 A;  4DMY A;  2PRE A;  2GHU A;  1IWD A;  2WBF X;  2ATO A;  1NQC A;  2YJB A;  3H7D A;  3IV2 A;  1CV8 A;  3BOW A;  3BC3 A;  2AUZ A;  2H7J A;  2P0R A;  4CDC B;  2DZY A;  3V6C A;  4FIP A;  4YV8 A;  3BPM A;  3PNR A;  3H8C A;  4OEM A;  1PE6 A;  4QRG A;  2XU5 A;  4B55 A;  2NQI A;  2FT2 A;  2E00 A;  2Y6E A;  1MEG A;  1QDQ A;  2FYE A;  3HWN A;  2E02 A;  4PP1 A;  2G6D A;  4BS5 A;  3PW3 A;  1ATK A;  4N4Z A;  3IHP A;  4BPV A;  2CB5 A;  2FO5 A;  2JQF R;  1QMY A;  3H89 A;  3K9M A;  1Q6K A;  6PAD A;  2XU3 A;  4I07 A;  1XKG A;  2FRQ A;  1AU2 A;  1NB5 A;  1CQD A;  3F5V A;  1U5I A;  4GUZ A;  1S4V A;  5JH3 A;  3CBK A;  5JA7 A;  3MHS A;  1PPN A;  1ITO A;  3ERV A;  1U9V A;  1MEM A;  2FRA A;  3RVW A;  4CDF B;  5FPW A;  4X6H A;  1W6F A;  2OUL A;  4CDE B;  2ARY A;  1EWL A;  8PCH A;  4PP2 E;  1ME3 A;  1KHP A;  4BSQ A;  1FH0 A;  2YJ8 A;  2DJF B;  1CB5 A;  2AIM A;  2JQG R;  2HH5 A;  1X9Y A;  1Y4H A;  1VJV A;  4MSX A;  4NV8 A;  3D6S A;  2B1M A;  1SNK A;  4P6E A;  4W4U A;  3HHI A;  4W5C A;  3DF0 A;  5K16 A;  3S3Q A;  4YYQ A;  1M6D A;  3S3R A;  1NPZ A;  3P5V A;  5PAD A;  1GX3 A;  4KLB A;  2VHF A;  4X6I A;  1KHQ A;  1YAL A;  2AYO A;  2PNS A;  3ZUA A;  2NQG A;  2BSZ A;  3D9W A;  1KFX L;  3CH3 X;  2R9M A;  3N4C A;  3KWZ A;  4RY2 A;  3KW9 A;  2R9F A;  3I3T A;  3C9E A;  1PIP A;  1JQP A;  3F75 A;  3WXF A;  1PBH A;  4G54 A;  5CVN B;  2AUX A;  1NLJ A;  3M99 A;  1ICF A;  3K8U A;  2AU1 A;  1BGO A;  3RVV A;  1K3B B;  3HHA A;  3O0U A;  1CS8 A;  2G7Y A;  2YJ2 A;  3BWK A;  1AU4 A;  3IMA A;  4ZUX U;  3MHH A;  1AYW A;  2AYN A;  1YT7 A;  3GCB A;  3USV A;  4N8W A;  4AXL A;  1NL6 A;  3OIS A;  3PBH A;  2VFC A;  1YK7 A;  4N79 A;  3CH2 X;  1F2B A;  2DC6 A;  3IOQ A;  1NB3 A;  3CBJ A;  2PAD A;  4PI3 A;  2XU4 A;  3B79 A;  5A24 A;  1ZCM A;  3H6S A;  4PAD A;  1U9Q X;  1ZIV A;  4I04 A;  2DCA A;  3V6E A;  2AS8 A;  1AU0 A;  1GMY A;  1TL9 A;  4Q8G A;  1O0E A;  4AXM A;  4QRV A;  4MZO A;  1GCB A;  2R9N A;  2ACT A;  4X6J A;  3QT4 A;  1CVZ A;  3P5W A;  1QOL A;  2IPP B;  4K7C A;  1BQI A;  4YVA A;  4W5B A;  4I05 A;  2DCC A;  1EWP A;  5F02 A;  2E03 A;  2FUD A;  3O1G A;  1CJL A;  1W4T A;  3MOR A;  4OEL A;  2AVW A;  3I06 A;  3IEJ A;  2G8J A;  3KWB X;  4DMX A;  2B1N A;  2OP3 A;  3E1Z B;  1STF E;  1EF7 A;  3N3G A;  1TU6 A;  4P6G A;  2G8E A;  3TNX A;  2DC7 A;  4QRX A;  9PAP A;  2DCD A;  2R9O A;  3OF8 A;  4YYS A;  4BGF A;  3P5U A;  4BQV A;  4QH6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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