3H8CA

A combined crystallographic and molecular dynamics study of cathepsin-l retro-binding inhibitors (compound 14)
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
220
structure length
214
Chain Sequence
APRSVDWREKGYVTPVKNQGQCGSWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Combined Crystallographic and Molecular Dynamics Study of Cathepsin L Retrobinding Inhibitors
pubmed doi rcsb
molecule keywords Cathepsin L1
molecule tags Hydrolase
source organism Homo sapiens
total genus 66
structure length 214
sequence length 220
chains with identical sequence B
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2009-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3h8cA00
2NQIA 2CIOA 2FRQA 4BS6A 4DMXA 1CS8A 3DF0A 1MEMA 2B1NA 3PBHA 3USVA 1ZCMA 4K7CA 4Q8HA 1YK8A 1DF0A 2ACTA 2AUZA 3K24A 1U5IA 4YYUA 2AYNA 3MHHA 3WXEA 3ZUAA 2DC8A 4PADA 3IEJA 1MIRA 4QH6A 4MSXA 1PE6A 2YJ8A 5J94A 1CJLA 4PI3A 2GFOA 1EWPA 2R9CA 3IOQA 4W5CA 4CDFB 4PP1A 3B79A 4P6EA 1M6DA 4YYSA 1GCBA 3H7DA 2HD5A 2XU3A 4YV8A 1F2CA 3KWZA 3F75A 1AU2A 2DC7A 2IPPB 3BPFA 2DCCA 4KLBA 5K16A 4AXLA 2JQGR 1MDWA 4FJCA 1PPNA 1GLOA 2G8JA 2R9NA 1PBHA 1AU3A 2CB5A 2BDLA 3K8UA 1CV8A 2DJGB 3RVXA 2AS8A 1F2BA 1O0EA 5JA7A 4P6GA 4XUIA 1AYUA 1QXPA 3H8BA 3WXGA 2FT2A 3C9EA 4YYQA 4FK5A 1Q6KA 2AUXA 3IV2A 3OVZA 3BPMA 1MEGA 4OEMA 2E01A 8PCHA 1VSNA 2E02A 1QDQA 1PIPA 3P5UA 4X6IA 2F1GA 3KWBX 1FH0A 1QMYA 1KHQA 1AU0A 2DCAA 1PADA 4I05A 4AXMA 5JH3A 4MZOA 2AU1A 1U9WA 1IWDA 1A6RA 3IHPA 1KFUL 4CDDB 2DCBA 1X9YA 2YJ2A 3N3KA 3OVXA 2VHFA 1SNKA 1ME4A 3H6SA 3P5XA 2FO5A 1EF7A 2DC6A 2AIMA 5CVMA 2C0YA 1YALA 1MHWA 7PCKA 4YYVA 2XU4A 2IBIA 3KX1A 1AECA 4QBBA 1NB5A 1KXRA 2Y6EA 3I3TA 3I06A 4CDEB 1CVZA 1F29A 2XU5A 4QRXA 1CB5A 2HHNA 1EWOA 1BQIA 3ERVA 1CSBB 1PPPA 3LXSA 4RY2A 1DEUA 3OF8A 4X6HA 1ZIVA 4N8WA 1GMYA 2FTDA 3S3QA 1PPDA 2P7UA 1YT7A 2G6DA 4OELA 1XKGA 2G8EA 3D6SA 3HHIA 3GCBA 1CQDA 2DZZA 3S3RA 4QRVA 4W5BA 1NQCA 2OZ2A 3HD3A 2ARYA 2OP3A 3O0UA 6PADA 2B1MA 1EWLA 2YJ9A 3H89A 4BSQA 2PREA 4FIPA 1YVBA 2HH5A 2HXZA 2E00A 1SP4B 3KW9A 3PDFA 3E1ZB 1BP4A 2XU1A 5PADA 3PNRA 3P5VA 2R9FA 3OF9A 2NQDB 3PW3A 2Y5BA 4Q8GA 4YYWA 1BY8A 1F2AA 1AYWA 2PADA 3MHSA 5CHTA 3M99A 3O1GA 1STFE 3TNXA 1ITOA 1U9QX 2DJFB 4BQVA 1JQPA 1TL9A 3N3GA 3CBKA 3QJ3A 2ATOA 3H8CA 2FYEA 2PNSA 2YJCA 2NQGA 3BWKA 3QT4A 4N4ZA 2WBFX 2H7JA 1YK7A 2PBHA 2E03A 2G7YA 5FPWA 1EWMA 1CPJA 1KHPA 2FUDA 1K3BB 2JQFR 4MZSA 1AYVA 1TLOA 3P5WA 3LFYA 1U9XA 2F7DA 3QSDA 1BGOA 1PXVA 3KSEA 3CH2X 4XR7A 4HWYA 1HUCB 3V6EA 4CDCB 2FQ9A 2AYOA 2DC9A 4W4UA 3IMAA 1NB3A 2O6XA 5A24A 3NHEA 1TU6A 4N79A 2FRAA 1ME3A 5EGWA 1NPZA 2AVWA 3BOWA 3HWNA 2P0RA 1U9VA 1QOLA 3F5VA 3N4CA 1VJVA 2DZYA 2R6NA 2YJBA 3KKUA 4BS5A 2R9MA 3AI8A 1CTEA 4G54A 1ATKA 3OISA 3U8EA 3KFQA 1PCIA 4WA6A 3HHAA 3BC3A 4QRGA 1Y08A 2BDZA 3CBJA 3BCNA 1MS6A 1ICFA 5CVOB 1NLJA 1POPA 1KFXL 2R9OA 3MORA 5CVNB 3CH3X 2DCDA 4DMYA 2GHUA 5F02A 2NQAA 4I07A 1NL6A 1PPOA 3MTNA 5EF4A 3IUTA 2VHSA 1S4VA 4CZWA 4PP2E 4BPVA 4X6JA 1AU4A 3V6CA 4I04A 3RVWA 3WXFA 2P86A 4YYRA 2OULA 1THEA 5CHVA 1Y4HA 4YVAA 1GECE 3RVVA 9PAPA 4ZUXU 1AIMA 3K9MA
chains in the Genus database with same CATH superfamily
3ZNHA 2NQIA 2CIOA 2FRQA 4BS6A 4DMXA 1CS8A 3DF0A 1MEMA 2B1NA 3PBHA 3USVA 1ZCMA 4K7CA 4Q8HA 3W31A 1YK8A 4D8IA 4P16A 1DF0A 2ACTA 2AUZA 3K24A 3OQCA 1U5IA 4YYUA 3BY4A 2AYNA 3MHHA 3WXEA 3ZUAA 2DC8A 4BOQA 4PADA 4ZTBA 3IEJA 3MTVA 1MIRA 4QH6A 3TMPA 4MSXA 1PE6A 2YJ8A 5J94A 1CJLA 4PI3A 2GFOA 1EWPA 2R9CA 3IOQA 4W5CA 4CDFB 4PP1A 3B79A 4P6EA 1M6DA 4YYSA 4WURA 1GCBA 3H7DA 2HD5A 2XU3A 4YV8A 1F2CA 3KWZA 4BOUA 3F75A 1AU2A 2DC7A 2IPPB 3BPFA 2DCCA 4KLBA 5K16A 4AXLA 4D8BA 2JQGR 1MDWA 4FJCA 1PPNA 1GLOA 2G8JA 2R9NA 1PBHA 1AU3A 2CB5A 2BDLA 3K8UA 1CV8A 3MP2A 2DJGB 3RVXA 2AS8A 1F2BA 1O0EA 5JA7A 4MM3B 4P6GA 4XUIA 1AYUA 1QXPA 3H8BA 3WXGA 2FT2A 4BOPA 4A5UA 3PHUA 2UZJA 3C9EA 4YYQA 4FK5A 1Q6KA 2AUXA 3IV2A 3OVZA 3BPMA 4GUAA 1MEGA 4OEMA 4RKXA 2E01A 8PCHA 1VSNA 2E02A 1QDQA 3PT2A 1PIPA 3BBAA 3P5UA 2HWKA 4X6IA 2F1GA 3KWBX 1FH0A 1QMYA 1KHQA 1AU0A 3C0RA 2DCAA 1PADA 3PRPA 4I05A 4AXMA 5JH3A 4MZOA 2AU1A 1U9WA 1IWDA 1A6RA 3IHPA 1KFUL 4CDDB 2DCBA 1X9YA 2YJ2A 3N3KA 3E9SA 3OVXA 2J7QC 2VHFA 1SNKA 1ME4A 3H6SA 5KO3A 3P5XA 2FO5A 1EF7A 2DC6A 2AIMA 5CVMA 4RF1A 2C0YA 1YALA 1MHWA 7PCKA 4YYVA 2XU4A 4M0WA 2IBIA 3KX1A 1AECA 3PHWA 3RNVA 4QBBA 1NB5A 1KXRA 2Y6EA 3I3TA 3I06A 4CDEB 1CVZA 1F29A 1YZBA 2XU5A 4QRXA 3B21A 3MJ5A 1CB5A 2HHNA 1EWOA 1BQIA 3ERVA 1CSBB 1PPPA 3LXSA 4RY2A 1DEUA 4OVZB 3OF8A 3PHXA 4X6HA 1ZIVA 4N8WA 1GMYA 2FTDA 3S3QA 1PPDA 2P7UA 1YT7A 2G6DA 4OELA 1XKGA 4OW0A 4OVZA 2G8EA 3TRKA 3D6SA 3HHIA 3GCBA 2FE8A 1CQDA 2DZZA 3S3RA 4RF0A 4QRVA 4W5BA 1NQCA 2OZ2A 3HD3A 2ARYA 2OP3A 3O0UA 6PADA 1DKIA 2B1MA 1EWLA 2YJ9A 2AGAA 3H89A 4BSQA 2PREA 4FIPA 1YVBA 2HH5A 2HXZA 2E00A 1SP4B 3KW9A 3PDFA 3E1ZB 5E6JA 1BP4A 4PT5A 2XU1A 5PADA 3PNRA 2JRIA 3P5VA 2R9FA 3OF9A 3W30A 2NQDB 3PW3A 2Y5BA 4Q8GA 4YYWA 1BY8A 1F2AA 1AYWA 2PADA 3MHSA 5CHTA 3M99A 3O1GA 1STFE 2DOSA 3TNXA 1ITOA 1U9QX 2DJFB 4D8EA 3IFUA 4BQVA 1JQPA 1TL9A 1UKFA 3N3GA 3CBKA 3QJ3A 2ATOA 3H8CA 2FYEA 2PNSA 2YJCA 4HXDB 2Z84A 2NQGA 3BWKA 3QT4A 4N4ZA 2WBFX 2H7JA 1YK7A 2PBHA 2E03A 2G7YA 4BOSA 5FPWA 1EWMA 1CPJA 1KHPA 2FUDA 1K3BB 2JQFR 4MZSA 1AYVA 1TLOA 3P5WA 3LFYA 1U9XA 3O65A 2F7DA 3QSDA 1BGOA 1PXVA 3KSEA 3CH2X 4IUMA 4XR7A 4HWYA 1HUCB 3V6EA 4CDCB 2FQ9A 2AYOA 2DC9A 4W4UA 3IMAA 1NB3A 2O6XA 3PSEA 5A24A 3NHEA 1TU6A 4N79A 2FRAA 1ME3A 5EGWA 1NPZA 2AVWA 3BOWA 3HWNA 2BTWB 2P0RA 1U9VA 4BOZA 1QOLA 3F5VA 3N4CA 1VJVA 2DZYA 2R6NA 2YJBA 2BTWA 3BB7A 3KKUA 4BS5A 2R9MA 3AI8A 1CTEA 4G54A 1ATKA 2J7QA 2JTCA 3OISA 2BU3A 3U8EA 3KFQA 1PCIA 4WA6A 3HHAA 3BC3A 4QRGA 1Y08A 2BDZA 3CBJA 3BCNA 1MS6A 1ICFA 5CVOB 5EZQA 4XZXA 1NLJA 1POPA 1KFXL 2R9OA 3MORA 4RNAA 4REZA 5CVNB 3CH3X 2DCDA 4DMYA 2GHUA 5F02A 2NQAA 4I07A 1NL6A 4R3DA 1PPOA 3MTNA 5EF4A 3IUTA 2VHSA 1S4VA 4CZWA 4PP2E 5EZSA 5JZEA 4BPVA 4X6JA 1AU4A 4MI7A 3V6CA 4I04A 3RVWA 3WXFA 2P86A 4YYRA 2OULA 1THEA 5CHVA 1Y4HA 3PRMA 4YVAA 1GECE 1PVJA 3RVVA 9PAPA 4IP3A 4ZUXU 1AIMA 3K9MA
chains in the Genus database with same CATH topology
2NQIA 2CIOA 2FRQA 4BS6A 4DMXA 1CS8A 3DF0A 1MEMA 2B1NA 3PBHA 3USVA 1ZCMA 4K7CA 4Q8HA 4NV7A 1YK8A 1DF0A 2ACTA 2AUZA 3K24A 1U5IA 4YYUA 2AYNA 3MHHA 3WXEA 3ZUAA 2DC8A 4PADA 3IEJA 1MIRA 4QH6A 4MSXA 1PE6A 2YJ8A 5J94A 1CJLA 4PI3A 2GFOA 1EWPA 2R9CA 3IOQA 4W5CA 4CDFB 4PP1A 3B79A 4P6EA 1M6DA 4YYSA 1GCBA 3H7DA 2HD5A 3LTWA 2XU3A 4YV8A 1F2CA 3KWZA 3F75A 1AU2A 2DC7A 2IPPB 3BPFA 2DCCA 4KLBA 5K16A 4AXLA 2JQGR 1MDWA 4FJCA 1PPNA 1GLOA 2G8JA 2R9NA 1PBHA 1AU3A 2CB5A 2BDLA 3K8UA 1CV8A 2DJGB 3RVXA 2AS8A 1F2BA 1O0EA 5JA7A 4P6GA 4XUIA 1AYUA 1QXPA 3H8BA 3WXGA 2FT2A 3C9EA 4YYQA 4FK5A 4NV8A 1Q6KA 2AUXA 3IV2A 3OVZA 3BPMA 1MEGA 4OEMA 2E01A 4GUZA 8PCHA 1VSNA 2E02A 1QDQA 1PIPA 2VFBA 3P5UA 4X6IA 2F1GA 3KWBX 1FH0A 1QMYA 1KHQA 1AU0A 2DCAA 1PADA 4I05A 4AXMA 5JH3A 4MZOA 2AU1A 1U9WA 1IWDA 1A6RA 3IHPA 1KFUL 4CDDB 2DCBA 1X9YA 2YJ2A 3N3KA 3OVXA 2VHFA 1SNKA 1ME4A 3H6SA 3P5XA 2FO5A 1EF7A 1W6FA 2DC6A 2AIMA 5CVMA 2C0YA 1YALA 1MHWA 2VFCA 7PCKA 4YYVA 2XU4A 2IBIA 3KX1A 1AECA 4QBBA 1NB5A 1KXRA 2Y6EA 3I3TA 4BGFA 3I06A 4CDEB 1CVZA 1F29A 2XU5A 4QRXA 4C5PA 1CB5A 2HHNA 1EWOA 1BQIA 3ERVA 1CSBB 1PPPA 3LXSA 4RY2A 1DEUA 3OF8A 1E2TA 4X6HA 1ZIVA 4N8WA 1GMYA 2FTDA 3S3QA 1PPDA 2P7UA 1YT7A 2G6DA 4OELA 1XKGA 2G8EA 3D6SA 3HHIA 3GCBA 1CQDA 2DZZA 3S3RA 4QRVA 4W5BA 1NQCA 2OZ2A 3HD3A 2ARYA 2OP3A 3O0UA 6PADA 2B1MA 1EWLA 2YJ9A 3H89A 4BSQA 2PREA 4FIPA 1YVBA 2HH5A 2HXZA 2E00A 1SP4B 3KW9A 3PDFA 3E1ZB 1BP4A 2XU1A 5PADA 3PNRA 3P5VA 2R9FA 3OF9A 2NQDB 3PW3A 2Y5BA 2BSZA 4Q8GA 4YYWA 1BY8A 1F2AA 1AYWA 2PADA 3MHSA 5CHTA 3M99A 3O1GA 1STFE 3TNXA 1ITOA 1U9QX 2DJFB 4BQVA 1JQPA 1TL9A 3N3GA 3CBKA 3QJ3A 2ATOA 3H8CA 2FYEA 2PNSA 2YJCA 2NQGA 3BWKA 3QT4A 4N4ZA 2WBFX 2H7JA 1YK7A 2PBHA 2E03A 2G7YA 3D9WA 5FPWA 1EWMA 1CPJA 1KHPA 2FUDA 1K3BB 2JQFR 4MZSA 1AYVA 1TLOA 3P5WA 3LFYA 1U9XA 2F7DA 3QSDA 1BGOA 1PXVA 3KSEA 3CH2X 4XR7A 4HWYA 1HUCB 3V6EA 4CDCB 2FQ9A 2AYOA 2DC9A 4W4UA 3IMAA 1NB3A 2O6XA 5A24A 3NHEA 1TU6A 4N79A 2FRAA 1ME3A 5EGWA 1NPZA 2AVWA 1W4TA 3BOWA 3HWNA 2P0RA 1U9VA 1QOLA 3F5VA 3N4CA 1VJVA 2DZYA 2R6NA 2YJBA 3KKUA 4BS5A 2R9MA 3AI8A 1CTEA 4G54A 1ATKA 3OISA 3U8EA 3KFQA 1PCIA 4WA6A 3HHAA 3BC3A 4QRGA 1Y08A 2BDZA 3CBJA 3BCNA 1MS6A 1ICFA 5CVOB 1NLJA 1POPA 1KFXL 2R9OA 3MORA 5CVNB 4B55A 3CH3X 2DCDA 4DMYA 2GHUA 5F02A 2NQAA 4I07A 1NL6A 1PPOA 3MTNA 5EF4A 1GX3A 1W5RA 3IUTA 2VHSA 1S4VA 4CZWA 4PP2E 4BPVA 4X6JA 1AU4A 3V6CA 4I04A 3RVWA 3WXFA 2P86A 4YYRA 2OULA 1THEA 5CHVA 1Y4HA 4YVAA 1GECE 3RVVA 9PAPA 4ZUXU 1AIMA 3K9MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NQI A;  2CIO A;  2FRQ A;  4BS6 A;  4DMX A;  1CS8 A;  3DF0 A;  1MEM A;  2B1N A;  3PBH A;  3USV A;  1ZCM A;  4K7C A;  4Q8H A;  1YK8 A;  1DF0 A;  2ACT A;  2AUZ A;  3K24 A;  1U5I A;  4YYU A;  2AYN A;  3MHH A;  3WXE A;  3ZUA A;  2DC8 A;  4PAD A;  3IEJ A;  1MIR A;  4QH6 A;  4MSX A;  1PE6 A;  2YJ8 A;  5J94 A;  1CJL A;  4PI3 A;  2GFO A;  1EWP A;  2R9C A;  3IOQ A;  4W5C A;  4CDF B;  4PP1 A;  3B79 A;  4P6E A;  1M6D A;  4YYS A;  1GCB A;  3H7D A;  2HD5 A;  2XU3 A;  4YV8 A;  1F2C A;  3KWZ A;  3F75 A;  1AU2 A;  2DC7 A;  2IPP B;  3BPF A;  2DCC A;  4KLB A;  5K16 A;  4AXL A;  2JQG R;  1MDW A;  4FJC A;  1PPN A;  1GLO A;  2G8J A;  2R9N A;  1PBH A;  1AU3 A;  2CB5 A;  2BDL A;  3K8U A;  1CV8 A;  2DJG B;  3RVX A;  2AS8 A;  1F2B A;  1O0E A;  5JA7 A;  4P6G A;  4XUI A;  1AYU A;  1QXP A;  3H8B A;  3WXG A;  2FT2 A;  3C9E A;  4YYQ A;  4FK5 A;  1Q6K A;  2AUX A;  3IV2 A;  3OVZ A;  3BPM A;  1MEG A;  4OEM A;  2E01 A;  8PCH A;  1VSN A;  2E02 A;  1QDQ A;  1PIP A;  3P5U A;  4X6I A;  2F1G A;  3KWB X;  1FH0 A;  1QMY A;  1KHQ A;  1AU0 A;  2DCA A;  1PAD A;  4I05 A;  4AXM A;  5JH3 A;  4MZO A;  2AU1 A;  1U9W A;  1IWD A;  1A6R A;  3IHP A;  1KFU L;  4CDD B;  2DCB A;  1X9Y A;  2YJ2 A;  3N3K A;  3OVX A;  2VHF A;  1SNK A;  1ME4 A;  3H6S A;  3P5X A;  2FO5 A;  1EF7 A;  2DC6 A;  2AIM A;  5CVM A;  2C0Y A;  1YAL A;  1MHW A;  7PCK A;  4YYV A;  2XU4 A;  2IBI A;  3KX1 A;  1AEC A;  4QBB A;  1NB5 A;  1KXR A;  2Y6E A;  3I3T A;  3I06 A;  4CDE B;  1CVZ A;  1F29 A;  2XU5 A;  4QRX A;  1CB5 A;  2HHN A;  1EWO A;  1BQI A;  3ERV A;  1CSB B;  1PPP A;  3LXS A;  4RY2 A;  1DEU A;  3OF8 A;  4X6H A;  1ZIV A;  4N8W A;  1GMY A;  2FTD A;  3S3Q A;  1PPD A;  2P7U A;  1YT7 A;  2G6D A;  4OEL A;  1XKG A;  2G8E A;  3D6S A;  3HHI A;  3GCB A;  1CQD A;  2DZZ A;  3S3R A;  4QRV A;  4W5B A;  1NQC A;  2OZ2 A;  3HD3 A;  2ARY A;  2OP3 A;  3O0U A;  6PAD A;  2B1M A;  1EWL A;  2YJ9 A;  3H89 A;  4BSQ A;  2PRE A;  4FIP A;  1YVB A;  2HH5 A;  2HXZ A;  2E00 A;  1SP4 B;  3KW9 A;  3PDF A;  3E1Z B;  1BP4 A;  2XU1 A;  5PAD A;  3PNR A;  3P5V A;  2R9F A;  3OF9 A;  2NQD B;  3PW3 A;  2Y5B A;  4Q8G A;  4YYW A;  1BY8 A;  1F2A A;  1AYW A;  2PAD A;  3MHS A;  5CHT A;  3M99 A;  3O1G A;  1STF E;  3TNX A;  1ITO A;  1U9Q X;  2DJF B;  4BQV A;  1JQP A;  1TL9 A;  3N3G A;  3CBK A;  3QJ3 A;  2ATO A;  3H8C A;  2FYE A;  2PNS A;  2YJC A;  2NQG A;  3BWK A;  3QT4 A;  4N4Z A;  2WBF X;  2H7J A;  1YK7 A;  2PBH A;  2E03 A;  2G7Y A;  5FPW A;  1EWM A;  1CPJ A;  1KHP A;  2FUD A;  1K3B B;  2JQF R;  4MZS A;  1AYV A;  1TLO A;  3P5W A;  3LFY A;  1U9X A;  2F7D A;  3QSD A;  1BGO A;  1PXV A;  3KSE A;  3CH2 X;  4XR7 A;  4HWY A;  1HUC B;  3V6E A;  4CDC B;  2FQ9 A;  2AYO A;  2DC9 A;  4W4U A;  3IMA A;  1NB3 A;  2O6X A;  5A24 A;  3NHE A;  1TU6 A;  4N79 A;  2FRA A;  1ME3 A;  5EGW A;  1NPZ A;  2AVW A;  3BOW A;  3HWN A;  2P0R A;  1U9V A;  1QOL A;  3F5V A;  3N4C A;  1VJV A;  2DZY A;  2R6N A;  2YJB A;  3KKU A;  4BS5 A;  2R9M A;  3AI8 A;  1CTE A;  4G54 A;  1ATK A;  3OIS A;  3U8E A;  3KFQ A;  1PCI A;  4WA6 A;  3HHA A;  3BC3 A;  4QRG A;  1Y08 A;  2BDZ A;  3CBJ A;  3BCN A;  1MS6 A;  1ICF A;  5CVO B;  1NLJ A;  1POP A;  1KFX L;  2R9O A;  3MOR A;  5CVN B;  3CH3 X;  2DCD A;  4DMY A;  2GHU A;  5F02 A;  2NQA A;  4I07 A;  1NL6 A;  1PPO A;  3MTN A;  5EF4 A;  3IUT A;  2VHS A;  1S4V A;  4CZW A;  4PP2 E;  4BPV A;  4X6J A;  1AU4 A;  3V6C A;  4I04 A;  3RVW A;  3WXF A;  2P86 A;  4YYR A;  2OUL A;  1THE A;  5CHV A;  1Y4H A;  4YVA A;  1GEC E;  3RVV A;  9PAP A;  4ZUX U;  1AIM A;  3K9M A; 
#chains in the Genus database with same CATH topology
 3ZNH A;  2NQI A;  2CIO A;  2FRQ A;  4BS6 A;  4DMX A;  1CS8 A;  3DF0 A;  1MEM A;  2B1N A;  3PBH A;  3USV A;  1ZCM A;  4K7C A;  4Q8H A;  3W31 A;  1YK8 A;  4D8I A;  4P16 A;  1DF0 A;  2ACT A;  2AUZ A;  3K24 A;  3OQC A;  1U5I A;  4YYU A;  3BY4 A;  2AYN A;  3MHH A;  3WXE A;  3ZUA A;  2DC8 A;  4BOQ A;  4PAD A;  4ZTB A;  3IEJ A;  3MTV A;  1MIR A;  4QH6 A;  3TMP A;  4MSX A;  1PE6 A;  2YJ8 A;  5J94 A;  1CJL A;  4PI3 A;  2GFO A;  1EWP A;  2R9C A;  3IOQ A;  4W5C A;  4CDF B;  4PP1 A;  3B79 A;  4P6E A;  1M6D A;  4YYS A;  4WUR A;  1GCB A;  3H7D A;  2HD5 A;  2XU3 A;  4YV8 A;  1F2C A;  3KWZ A;  4BOU A;  3F75 A;  1AU2 A;  2DC7 A;  2IPP B;  3BPF A;  2DCC A;  4KLB A;  5K16 A;  4AXL A;  4D8B A;  2JQG R;  1MDW A;  4FJC A;  1PPN A;  1GLO A;  2G8J A;  2R9N A;  1PBH A;  1AU3 A;  2CB5 A;  2BDL A;  3K8U A;  1CV8 A;  3MP2 A;  2DJG B;  3RVX A;  2AS8 A;  1F2B A;  1O0E A;  5JA7 A;  4MM3 B;  4P6G A;  4XUI A;  1AYU A;  1QXP A;  3H8B A;  3WXG A;  2FT2 A;  4BOP A;  4A5U A;  3PHU A;  2UZJ A;  3C9E A;  4YYQ A;  4FK5 A;  1Q6K A;  2AUX A;  3IV2 A;  3OVZ A;  3BPM A;  4GUA A;  1MEG A;  4OEM A;  4RKX A;  2E01 A;  8PCH A;  1VSN A;  2E02 A;  1QDQ A;  3PT2 A;  1PIP A;  3BBA A;  3P5U A;  2HWK A;  4X6I A;  2F1G A;  3KWB X;  1FH0 A;  1QMY A;  1KHQ A;  1AU0 A;  3C0R A;  2DCA A;  1PAD A;  3PRP A;  4I05 A;  4AXM A;  5JH3 A;  4MZO A;  2AU1 A;  1U9W A;  1IWD A;  1A6R A;  3IHP A;  1KFU L;  4CDD B;  2DCB A;  1X9Y A;  2YJ2 A;  3N3K A;  3E9S A;  3OVX A;  2J7Q C;  2VHF A;  1SNK A;  1ME4 A;  3H6S A;  5KO3 A;  3P5X A;  2FO5 A;  1EF7 A;  2DC6 A;  2AIM A;  5CVM A;  4RF1 A;  2C0Y A;  1YAL A;  1MHW A;  7PCK A;  4YYV A;  2XU4 A;  4M0W A;  2IBI A;  3KX1 A;  1AEC A;  3PHW A;  3RNV A;  4QBB A;  1NB5 A;  1KXR A;  2Y6E A;  3I3T A;  3I06 A;  4CDE B;  1CVZ A;  1F29 A;  1YZB A;  2XU5 A;  4QRX A;  3B21 A;  3MJ5 A;  1CB5 A;  2HHN A;  1EWO A;  1BQI A;  3ERV A;  1CSB B;  1PPP A;  3LXS A;  4RY2 A;  1DEU A;  4OVZ B;  3OF8 A;  3PHX A;  4X6H A;  1ZIV A;  4N8W A;  1GMY A;  2FTD A;  3S3Q A;  1PPD A;  2P7U A;  1YT7 A;  2G6D A;  4OEL A;  1XKG A;  4OW0 A;  4OVZ A;  2G8E A;  3TRK A;  3D6S A;  3HHI A;  3GCB A;  2FE8 A;  1CQD A;  2DZZ A;  3S3R A;  4RF0 A;  4QRV A;  4W5B A;  1NQC A;  2OZ2 A;  3HD3 A;  2ARY A;  2OP3 A;  3O0U A;  6PAD A;  1DKI A;  2B1M A;  1EWL A;  2YJ9 A;  2AGA A;  3H89 A;  4BSQ A;  2PRE A;  4FIP A;  1YVB A;  2HH5 A;  2HXZ A;  2E00 A;  1SP4 B;  3KW9 A;  3PDF A;  3E1Z B;  5E6J A;  1BP4 A;  4PT5 A;  2XU1 A;  5PAD A;  3PNR A;  2JRI A;  3P5V A;  2R9F A;  3OF9 A;  3W30 A;  2NQD B;  3PW3 A;  2Y5B A;  4Q8G A;  4YYW A;  1BY8 A;  1F2A A;  1AYW A;  2PAD A;  3MHS A;  5CHT A;  3M99 A;  3O1G A;  1STF E;  2DOS A;  3TNX A;  1ITO A;  1U9Q X;  2DJF B;  4D8E A;  3IFU A;  4BQV A;  1JQP A;  1TL9 A;  1UKF A;  3N3G A;  3CBK A;  3QJ3 A;  2ATO A;  3H8C A;  2FYE A;  2PNS A;  2YJC A;  4HXD B;  2Z84 A;  2NQG A;  3BWK A;  3QT4 A;  4N4Z A;  2WBF X;  2H7J A;  1YK7 A;  2PBH A;  2E03 A;  2G7Y A;  4BOS A;  5FPW A;  1EWM A;  1CPJ A;  1KHP A;  2FUD A;  1K3B B;  2JQF R;  4MZS A;  1AYV A;  1TLO A;  3P5W A;  3LFY A;  1U9X A;  3O65 A;  2F7D A;  3QSD A;  1BGO A;  1PXV A;  3KSE A;  3CH2 X;  4IUM A;  4XR7 A;  4HWY A;  1HUC B;  3V6E A;  4CDC B;  2FQ9 A;  2AYO A;  2DC9 A;  4W4U A;  3IMA A;  1NB3 A;  2O6X A;  3PSE A;  5A24 A;  3NHE A;  1TU6 A;  4N79 A;  2FRA A;  1ME3 A;  5EGW A;  1NPZ A;  2AVW A;  3BOW A;  3HWN A;  2BTW B;  2P0R A;  1U9V A;  4BOZ A;  1QOL A;  3F5V A;  3N4C A;  1VJV A;  2DZY A;  2R6N A;  2YJB A;  2BTW A;  3BB7 A;  3KKU A;  4BS5 A;  2R9M A;  3AI8 A;  1CTE A;  4G54 A;  1ATK A;  2J7Q A;  2JTC A;  3OIS A;  2BU3 A;  3U8E A;  3KFQ A;  1PCI A;  4WA6 A;  3HHA A;  3BC3 A;  4QRG A;  1Y08 A;  2BDZ A;  3CBJ A;  3BCN A;  1MS6 A;  1ICF A;  5CVO B;  5EZQ A;  4XZX A;  1NLJ A;  1POP A;  1KFX L;  2R9O A;  3MOR A;  4RNA A;  4REZ A;  5CVN B;  3CH3 X;  2DCD A;  4DMY A;  2GHU A;  5F02 A;  2NQA A;  4I07 A;  1NL6 A;  4R3D A;  1PPO A;  3MTN A;  5EF4 A;  3IUT A;  2VHS A;  1S4V A;  4CZW A;  4PP2 E;  5EZS A;  5JZE A;  4BPV A;  4X6J A;  1AU4 A;  4MI7 A;  3V6C A;  4I04 A;  3RVW A;  3WXF A;  2P86 A;  4YYR A;  2OUL A;  1THE A;  5CHV A;  1Y4H A;  3PRM A;  4YVA A;  1GEC E;  1PVJ A;  3RVV A;  9PAP A;  4IP3 A;  4ZUX U;  1AIM A;  3K9M A; 
#chains in the Genus database with same CATH homology
 2NQI A;  2CIO A;  2FRQ A;  4BS6 A;  4DMX A;  1CS8 A;  3DF0 A;  1MEM A;  2B1N A;  3PBH A;  3USV A;  1ZCM A;  4K7C A;  4Q8H A;  4NV7 A;  1YK8 A;  1DF0 A;  2ACT A;  2AUZ A;  3K24 A;  1U5I A;  4YYU A;  2AYN A;  3MHH A;  3WXE A;  3ZUA A;  2DC8 A;  4PAD A;  3IEJ A;  1MIR A;  4QH6 A;  4MSX A;  1PE6 A;  2YJ8 A;  5J94 A;  1CJL A;  4PI3 A;  2GFO A;  1EWP A;  2R9C A;  3IOQ A;  4W5C A;  4CDF B;  4PP1 A;  3B79 A;  4P6E A;  1M6D A;  4YYS A;  1GCB A;  3H7D A;  2HD5 A;  3LTW A;  2XU3 A;  4YV8 A;  1F2C A;  3KWZ A;  3F75 A;  1AU2 A;  2DC7 A;  2IPP B;  3BPF A;  2DCC A;  4KLB A;  5K16 A;  4AXL A;  2JQG R;  1MDW A;  4FJC A;  1PPN A;  1GLO A;  2G8J A;  2R9N A;  1PBH A;  1AU3 A;  2CB5 A;  2BDL A;  3K8U A;  1CV8 A;  2DJG B;  3RVX A;  2AS8 A;  1F2B A;  1O0E A;  5JA7 A;  4P6G A;  4XUI A;  1AYU A;  1QXP A;  3H8B A;  3WXG A;  2FT2 A;  3C9E A;  4YYQ A;  4FK5 A;  4NV8 A;  1Q6K A;  2AUX A;  3IV2 A;  3OVZ A;  3BPM A;  1MEG A;  4OEM A;  2E01 A;  4GUZ A;  8PCH A;  1VSN A;  2E02 A;  1QDQ A;  1PIP A;  2VFB A;  3P5U A;  4X6I A;  2F1G A;  3KWB X;  1FH0 A;  1QMY A;  1KHQ A;  1AU0 A;  2DCA A;  1PAD A;  4I05 A;  4AXM A;  5JH3 A;  4MZO A;  2AU1 A;  1U9W A;  1IWD A;  1A6R A;  3IHP A;  1KFU L;  4CDD B;  2DCB A;  1X9Y A;  2YJ2 A;  3N3K A;  3OVX A;  2VHF A;  1SNK A;  1ME4 A;  3H6S A;  3P5X A;  2FO5 A;  1EF7 A;  1W6F A;  2DC6 A;  2AIM A;  5CVM A;  2C0Y A;  1YAL A;  1MHW A;  2VFC A;  7PCK A;  4YYV A;  2XU4 A;  2IBI A;  3KX1 A;  1AEC A;  4QBB A;  1NB5 A;  1KXR A;  2Y6E A;  3I3T A;  4BGF A;  3I06 A;  4CDE B;  1CVZ A;  1F29 A;  2XU5 A;  4QRX A;  4C5P A;  1CB5 A;  2HHN A;  1EWO A;  1BQI A;  3ERV A;  1CSB B;  1PPP A;  3LXS A;  4RY2 A;  1DEU A;  3OF8 A;  1E2T A;  4X6H A;  1ZIV A;  4N8W A;  1GMY A;  2FTD A;  3S3Q A;  1PPD A;  2P7U A;  1YT7 A;  2G6D A;  4OEL A;  1XKG A;  2G8E A;  3D6S A;  3HHI A;  3GCB A;  1CQD A;  2DZZ A;  3S3R A;  4QRV A;  4W5B A;  1NQC A;  2OZ2 A;  3HD3 A;  2ARY A;  2OP3 A;  3O0U A;  6PAD A;  2B1M A;  1EWL A;  2YJ9 A;  3H89 A;  4BSQ A;  2PRE A;  4FIP A;  1YVB A;  2HH5 A;  2HXZ A;  2E00 A;  1SP4 B;  3KW9 A;  3PDF A;  3E1Z B;  1BP4 A;  2XU1 A;  5PAD A;  3PNR A;  3P5V A;  2R9F A;  3OF9 A;  2NQD B;  3PW3 A;  2Y5B A;  2BSZ A;  4Q8G A;  4YYW A;  1BY8 A;  1F2A A;  1AYW A;  2PAD A;  3MHS A;  5CHT A;  3M99 A;  3O1G A;  1STF E;  3TNX A;  1ITO A;  1U9Q X;  2DJF B;  4BQV A;  1JQP A;  1TL9 A;  3N3G A;  3CBK A;  3QJ3 A;  2ATO A;  3H8C A;  2FYE A;  2PNS A;  2YJC A;  2NQG A;  3BWK A;  3QT4 A;  4N4Z A;  2WBF X;  2H7J A;  1YK7 A;  2PBH A;  2E03 A;  2G7Y A;  3D9W A;  5FPW A;  1EWM A;  1CPJ A;  1KHP A;  2FUD A;  1K3B B;  2JQF R;  4MZS A;  1AYV A;  1TLO A;  3P5W A;  3LFY A;  1U9X A;  2F7D A;  3QSD A;  1BGO A;  1PXV A;  3KSE A;  3CH2 X;  4XR7 A;  4HWY A;  1HUC B;  3V6E A;  4CDC B;  2FQ9 A;  2AYO A;  2DC9 A;  4W4U A;  3IMA A;  1NB3 A;  2O6X A;  5A24 A;  3NHE A;  1TU6 A;  4N79 A;  2FRA A;  1ME3 A;  5EGW A;  1NPZ A;  2AVW A;  1W4T A;  3BOW A;  3HWN A;  2P0R A;  1U9V A;  1QOL A;  3F5V A;  3N4C A;  1VJV A;  2DZY A;  2R6N A;  2YJB A;  3KKU A;  4BS5 A;  2R9M A;  3AI8 A;  1CTE A;  4G54 A;  1ATK A;  3OIS A;  3U8E A;  3KFQ A;  1PCI A;  4WA6 A;  3HHA A;  3BC3 A;  4QRG A;  1Y08 A;  2BDZ A;  3CBJ A;  3BCN A;  1MS6 A;  1ICF A;  5CVO B;  1NLJ A;  1POP A;  1KFX L;  2R9O A;  3MOR A;  5CVN B;  4B55 A;  3CH3 X;  2DCD A;  4DMY A;  2GHU A;  5F02 A;  2NQA A;  4I07 A;  1NL6 A;  1PPO A;  3MTN A;  5EF4 A;  1GX3 A;  1W5R A;  3IUT A;  2VHS A;  1S4V A;  4CZW A;  4PP2 E;  4BPV A;  4X6J A;  1AU4 A;  3V6C A;  4I04 A;  3RVW A;  3WXF A;  2P86 A;  4YYR A;  2OUL A;  1THE A;  5CHV A;  1Y4H A;  4YVA A;  1GEC E;  3RVV A;  9PAP A;  4ZUX U;  1AIM A;  3K9M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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