1VSNA

Crystal structure of a potent small molecule inhibitor bound to cathepsin k
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
215
structure length
215
Chain Sequence
APDSIDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKATGALLNLAPQNLVDCVSENDGCGGGYMTNAFQYVQRNRGIDSEDAYPYVGQDESCMYNPTGKAAKCRGYREIPEGNEAALKRAVAAVGPVSVAIDASLTSFQFYSAGVYYDENCSSDALNHAVLAVGYGIQAGNKHWIIKNSWGESWGNAGYILMARNKNNACGIANLASFPKM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification of a potent and selective non-basic cathepsin K inhibitor.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Cathepsin K
total genus 62
structure length 215
sequence length 215
ec nomenclature ec 3.4.22.38: Cathepsin K.
pdb deposition date 2007-03-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1vsnA00
3I06A 3H7DA 3BCNA 3F5VA 4I04A 2AIMA 2XU4A 2AVWA 2R9NA 2FTDA 1MHWA 4CZWA 4QRGA 2HXZA 3S3QA 1F2CA 1XKGA 1PPOA 2VHSA 5CVOB 2AUZA 3V6EA 4P6EA 1QXPA 4X6HA 3RVVA 5EF4A 1DEUA 1SNKA 4YV8A 3GCBA 1SP4B 2JQGR 1MDWA 2XU5A 4AXLA 1GCBA 3AI8A 1NQCA 2HH5A 1CQDA 1PXVA 2NQIA 3B79A 3MHSA 5F02A 2HD5A 2CB5A 2DCBA 2YJ2A 3D6SA 4WA6A 2DC9A 4AXMA 1CV8A 1MEGA 2AUXA 2NQDB 1CB5A 3HD3A 1U5IA 2DCAA 3P5XA 2GFOA 2GHUA 1PBHA 2AYNA 2IBIA 1BQIA 2AU1A 2DZYA 3MHHA 2DC7A 1KFUL 3ERVA 1X9YA 4YYUA 1U9WA 2BDZA 4HWYA 4XR7A 1AU4A 1VJVA 3IOQA 1ICFA 1GLOA 1ZIVA 4BS6A 1ATKA 4XUIA 2ACTA 1AYUA 1BY8A 3HHAA 3MORA 5FPWA 2O6XA 2FQ9A 2DC8A 1EWMA 1AU3A 1KHQA 4N79A 3NHEA 3KFQA 4QBBA 2DCCA 1ME3A 2PADA 4P6GA 4QRVA 3M99A 2Y6EA 3P5VA 1U9VA 5K16A 2AS8A 1AYWA 3PNRA 8PCHA 1NB5A 1F2AA 4G54A 3H89A 5CHVA 1CSBB 4W5CA 5A24A 1ME4A 3IHPA 2DJFB 4CDFB 1MEMA 2JQFR 1MIRA 3BWKA 3H6SA 2YJBA 3KWZA 4W4UA 1NL6A 1NB3A 2PREA 4N4ZA 3IV2A 4QH6A 1AYVA 3N3GA 3WXGA 3LFYA 3U8EA 2HHNA 1PPPA 2FRAA 1AECA 4MZOA 1BGOA 1PPNA 4FK5A 6PADA 1EF7A 7PCKA 4I07A 1QOLA 2YJ8A 1YK7A 1A6RA 1NLJA 1HUCB 1M6DA 3RVXA 4CDCB 1GECE 4OEMA 3V6CA 4N8WA 4BSQA 3O0UA 3P5WA 2XU3A 2G6DA 2BDLA 3K24A 3PBHA 2NQGA 2DCDA 2R9OA 2AYOA 2OULA 1YT7A 4Q8GA 3I3TA 4PI3A 3MTNA 1KXRA 1MS6A 3KKUA 3WXFA 1POPA 3USVA 3N4CA 4DMXA 3QT4A 2OZ2A 1K3BB 2YJCA 4CDDB 1TLOA 1F2BA 4RY2A 3BPMA 3HWNA 1Y4HA 2XU1A 2R9CA 4K7CA 1STFE 3KSEA 4YYSA 1EWPA 2P86A 3BPFA 5JH3A 2G8JA 4YYWA 2R9MA 2P7UA 4X6IA 3K8UA 1AU2A 3TNXA 2E03A 3N3KA 3LXSA 4YYQA 3E1ZB 1PADA 3H8CA 2FT2A 3OF9A 2IPPB 1DF0A 1CTEA 3KX1A 4I05A 4PADA 2G7YA 3OF8A 4FIPA 2PBHA 3C9EA 5PADA 2R9FA 9PAPA 5JA7A 3CH2X 2ATOA 5CVNB 3KW9A 3HHIA 1THEA 2WBFX 2G8EA 3OVXA 1QMYA 2E02A 2E01A 4QRXA 4YYVA 3WXEA 3CBKA 3DF0A 1ZCMA 4W5BA 1KHPA 2PNSA 4FJCA 3RVWA 5CVMA 1CJLA 4PP1A 1O0EA 4Q8HA 3CH3X 3BOWA 3K9MA 4BQVA 3QJ3A 2P0RA 3IUTA 4KLBA 1JQPA 1CS8A 1AU0A 1PE6A 4BS5A 2F1GA 2F7DA 3QSDA 1TU6A 3O1GA 4ZUXU 2OP3A 2FUDA 1FH0A 1BP4A 4YVAA 3S3RA 1U9QX 4PP2E 3F75A 4YYRA 4CDEB 1EWLA 5CHTA 1ITOA 1Y08A 1PCIA 5J94A 3CBJA 3PW3A 1GMYA 1AIMA 1F29A 1PIPA 2R6NA 1TL9A 4BPVA 3BC3A 3OVZA 1NPZA 3OISA 2B1NA 2FO5A 2Y5BA 1YALA 2YJ9A 3KWBX 2FYEA 4OELA 1CPJA 5EGWA 2NQAA 3PDFA 2CIOA 1YK8A 2B1MA 2FRQA 1EWOA 3P5UA 2DC6A 1VSNA 4MZSA 1CVZA 1U9XA 1S4VA 4MSXA 1YVBA 1QDQA 1KFXL 1Q6KA 3IMAA 3ZUAA 3H8BA 4DMYA 4X6JA 1IWDA 2DZZA 2ARYA 1PPDA 2H7JA 2VHFA 2C0YA 2E00A 3IEJA 2DJGB
chains in the Genus database with same CATH superfamily
3I06A 3H7DA 3BCNA 3F5VA 4I04A 2AIMA 4A5UA 2XU4A 2AVWA 2R9NA 2FTDA 1MHWA 4CZWA 4QRGA 2HXZA 3S3QA 1F2CA 1XKGA 1PPOA 2VHSA 5CVOB 2AUZA 4MI7A 3V6EA 4P6EA 1QXPA 4X6HA 3RVVA 5EF4A 1DEUA 3BB7A 1SNKA 4YV8A 3GCBA 1SP4B 5JZEA 3W31A 2JQGR 1MDWA 2HWKA 2XU5A 4AXLA 1GCBA 3AI8A 1NQCA 2HH5A 1CQDA 1PXVA 2NQIA 3B79A 4PT5A 3MHSA 4RNAA 5F02A 2HD5A 2CB5A 2DCBA 2YJ2A 4WURA 4MM3B 3D6SA 4WA6A 3C0RA 2DC9A 4AXMA 1CV8A 1MEGA 2AUXA 2BTWA 2NQDB 1CB5A 3HD3A 1U5IA 2DCAA 3TRKA 3P5XA 2GFOA 2GHUA 1PBHA 3MTVA 2AYNA 2IBIA 1BQIA 2AU1A 2DZYA 3MHHA 2DC7A 1KFUL 4OVZB 3ERVA 4BOPA 1X9YA 4YYUA 1U9WA 2BDZA 4HWYA 4XR7A 1AU4A 1VJVA 3IOQA 1ICFA 4D8IA 1GLOA 1ZIVA 2FE8A 4BS6A 1ATKA 4XUIA 2ACTA 1AYUA 1BY8A 3HHAA 3MORA 5FPWA 2O6XA 2FQ9A 2DC8A 1EWMA 3O65A 3PT2A 1AU3A 1KHQA 4N79A 3NHEA 3KFQA 2JTCA 4QBBA 2DCCA 1ME3A 2PADA 4P6GA 4QRVA 3M99A 2JRIA 2Y6EA 3P5VA 1U9VA 5K16A 2J7QC 2AS8A 1AYWA 3PNRA 8PCHA 1NB5A 3B21A 1F2AA 4G54A 3H89A 4GUAA 5CHVA 1CSBB 4W5CA 4OW0A 5A24A 1UKFA 1ME4A 3IHPA 2DJFB 4CDFB 1MEMA 2JQFR 1MIRA 3BWKA 3H6SA 2YJBA 3KWZA 4W4UA 1NL6A 1NB3A 2PREA 4N4ZA 3IV2A 4QH6A 1AYVA 3N3GA 3WXGA 3LFYA 3U8EA 2HHNA 1PPPA 2FRAA 1AECA 4MZOA 1BGOA 1PPNA 4FK5A 6PADA 1EF7A 7PCKA 4I07A 1QOLA 2YJ8A 1YK7A 1A6RA 1NLJA 3MJ5A 1HUCB 1M6DA 3RVXA 4CDCB 1GECE 4OEMA 3V6CA 4N8WA 4BSQA 4XZXA 2BU3A 3O0UA 3P5WA 4D8BA 2XU3A 2G6DA 2BDLA 3K24A 3PBHA 2NQGA 4P16A 2DCDA 2R9OA 2AYOA 2OULA 1YT7A 4Q8GA 3I3TA 4PI3A 4ZTBA 3MTNA 1KXRA 1MS6A 3KKUA 3WXFA 1POPA 3USVA 3N4CA 4DMXA 3QT4A 2OZ2A 3PHWA 1K3BB 2YJCA 4CDDB 3IFUA 4OVZA 1TLOA 1F2BA 5EZQA 4RY2A 3BPMA 3PRMA 3HWNA 1Y4HA 2XU1A 2R9CA 4K7CA 1STFE 3KSEA 4YYSA 1EWPA 2P86A 3RNVA 4D8EA 3BPFA 5JH3A 2G8JA 4YYWA 2R9MA 2P7UA 4X6IA 3PHXA 3K8UA 1AU2A 3TNXA 2DOSA 2E03A 3BY4A 3N3KA 3LXSA 4YYQA 3E1ZB 1PADA 3H8CA 4M0WA 2FT2A 3OF9A 2IPPB 1DF0A 3TMPA 1CTEA 1PVJA 3KX1A 4I05A 4PADA 2G7YA 3OF8A 4FIPA 2PBHA 3C9EA 5PADA 2R9FA 3W30A 9PAPA 5JA7A 4IP3A 3CH2X 2ATOA 5CVNB 3KW9A 3HHIA 3PSEA 4BOQA 1THEA 2WBFX 2G8EA 3OVXA 1QMYA 2E02A 2Z84A 2E01A 4QRXA 4YYVA 3WXEA 3CBKA 1YZBA 3DF0A 1ZCMA 4W5BA 1KHPA 2PNSA 3PHUA 4FJCA 3RVWA 5CVMA 1CJLA 2UZJA 4PP1A 4BOSA 1O0EA 4Q8HA 3CH3X 5E6JA 3BOWA 3K9MA 4REZA 4BQVA 3QJ3A 2P0RA 4R3DA 1DKIA 3IUTA 4KLBA 1JQPA 1CS8A 1AU0A 1PE6A 4BS5A 2F1GA 2F7DA 3QSDA 1TU6A 3O1GA 4BOZA 4ZUXU 2OP3A 2FUDA 1FH0A 1BP4A 4YVAA 2J7QA 3S3RA 5KO3A 1U9QX 4PP2E 3F75A 4YYRA 4CDEB 2BTWB 4RF0A 1EWLA 5CHTA 1ITOA 1Y08A 1PCIA 5J94A 3CBJA 3PW3A 1GMYA 1AIMA 1F29A 2AGAA 4HXDB 1PIPA 2R6NA 1TL9A 4BPVA 3BC3A 3OVZA 1NPZA 3OISA 2B1NA 3PRPA 2FO5A 2Y5BA 1YALA 2YJ9A 3KWBX 2FYEA 4OELA 1CPJA 5EGWA 2NQAA 4BOUA 3PDFA 4IUMA 2CIOA 1YK8A 3OQCA 2B1MA 5EZSA 2FRQA 3BBAA 1EWOA 3P5UA 3E9SA 2DC6A 1VSNA 4RF1A 4MZSA 1CVZA 1U9XA 1S4VA 3MP2A 4MSXA 1YVBA 1QDQA 1KFXL 1Q6KA 3IMAA 3ZUAA 3H8BA 4DMYA 4X6JA 1IWDA 2DZZA 2ARYA 1PPDA 4RKXA 2H7JA 3ZNHA 2VHFA 2C0YA 2E00A 3IEJA 2DJGB
chains in the Genus database with same CATH topology
3I06A 3H7DA 3BCNA 3F5VA 4I04A 2AIMA 2XU4A 2AVWA 2R9NA 2FTDA 1MHWA 4CZWA 4QRGA 2HXZA 2VFCA 3S3QA 1F2CA 1XKGA 1PPOA 2VHSA 5CVOB 2AUZA 3V6EA 4P6EA 1QXPA 4X6HA 3RVVA 1W5RA 1W4TA 5EF4A 1DEUA 1SNKA 4YV8A 1E2TA 3GCBA 1SP4B 2JQGR 1MDWA 2XU5A 4AXLA 1GCBA 3AI8A 1NQCA 2HH5A 1CQDA 1PXVA 2NQIA 3B79A 3MHSA 5F02A 2HD5A 2CB5A 2DCBA 2YJ2A 3D6SA 4WA6A 2DC9A 4AXMA 1CV8A 1MEGA 2AUXA 2NQDB 1CB5A 3HD3A 1U5IA 1W6FA 2DCAA 3P5XA 2GFOA 2GHUA 1PBHA 2AYNA 2IBIA 1BQIA 2AU1A 2DZYA 3MHHA 2DC7A 1KFUL 3ERVA 1X9YA 4YYUA 1U9WA 2BDZA 4HWYA 4XR7A 1AU4A 1VJVA 3IOQA 1ICFA 1GLOA 1ZIVA 4BS6A 1ATKA 4XUIA 2ACTA 1AYUA 1BY8A 3HHAA 3MORA 5FPWA 2O6XA 2FQ9A 2DC8A 1EWMA 1AU3A 1KHQA 4N79A 3NHEA 3KFQA 4QBBA 2DCCA 1ME3A 2PADA 4P6GA 4QRVA 3M99A 2Y6EA 3P5VA 1U9VA 5K16A 2AS8A 1AYWA 3PNRA 8PCHA 1NB5A 1F2AA 4G54A 3H89A 5CHVA 1CSBB 4W5CA 5A24A 1ME4A 3IHPA 2DJFB 4CDFB 3D9WA 1MEMA 2JQFR 1MIRA 3BWKA 3H6SA 2YJBA 3KWZA 4W4UA 1NL6A 1NB3A 2PREA 4N4ZA 3IV2A 4QH6A 1AYVA 3N3GA 3WXGA 3LFYA 3U8EA 2HHNA 1PPPA 2FRAA 1AECA 4MZOA 1BGOA 1PPNA 4FK5A 6PADA 1EF7A 7PCKA 4I07A 1QOLA 2YJ8A 1YK7A 1A6RA 1NLJA 1HUCB 1M6DA 3RVXA 4CDCB 1GECE 4OEMA 3V6CA 4N8WA 4BSQA 3O0UA 3P5WA 2XU3A 2G6DA 2BDLA 3K24A 3PBHA 2NQGA 2DCDA 2R9OA 2AYOA 2OULA 1YT7A 4Q8GA 3I3TA 4GUZA 4PI3A 3MTNA 1KXRA 1MS6A 3KKUA 3WXFA 1POPA 3USVA 3N4CA 4DMXA 3QT4A 4NV7A 2OZ2A 4C5PA 4NV8A 1K3BB 2YJCA 4CDDB 1TLOA 1F2BA 4RY2A 1GX3A 3BPMA 4BGFA 3HWNA 1Y4HA 2XU1A 2R9CA 4K7CA 1STFE 3KSEA 4YYSA 1EWPA 2VFBA 2P86A 3BPFA 5JH3A 2G8JA 4YYWA 2R9MA 2P7UA 4X6IA 3K8UA 1AU2A 3TNXA 2E03A 3N3KA 3LXSA 4YYQA 3E1ZB 1PADA 3H8CA 2FT2A 3OF9A 2IPPB 1DF0A 1CTEA 2BSZA 3KX1A 4I05A 4PADA 2G7YA 3OF8A 4FIPA 2PBHA 3C9EA 5PADA 2R9FA 9PAPA 5JA7A 3CH2X 2ATOA 5CVNB 3KW9A 3HHIA 1THEA 2WBFX 2G8EA 3OVXA 1QMYA 2E02A 2E01A 4QRXA 4YYVA 3WXEA 3CBKA 3DF0A 1ZCMA 4W5BA 1KHPA 2PNSA 4FJCA 3RVWA 5CVMA 1CJLA 4PP1A 3LTWA 1O0EA 4Q8HA 3CH3X 3BOWA 3K9MA 4BQVA 3QJ3A 2P0RA 3IUTA 4KLBA 1JQPA 1CS8A 1AU0A 1PE6A 4BS5A 2F1GA 2F7DA 3QSDA 1TU6A 3O1GA 4ZUXU 2OP3A 2FUDA 1FH0A 1BP4A 4YVAA 3S3RA 1U9QX 4PP2E 3F75A 4YYRA 4CDEB 1EWLA 5CHTA 1ITOA 1Y08A 1PCIA 5J94A 3CBJA 3PW3A 1GMYA 1AIMA 1F29A 1PIPA 2R6NA 1TL9A 4BPVA 3BC3A 3OVZA 1NPZA 3OISA 2B1NA 2FO5A 2Y5BA 1YALA 2YJ9A 3KWBX 2FYEA 4OELA 1CPJA 5EGWA 2NQAA 3PDFA 2CIOA 1YK8A 2B1MA 2FRQA 4B55A 1EWOA 3P5UA 2DC6A 1VSNA 4MZSA 1CVZA 1U9XA 1S4VA 4MSXA 1YVBA 1QDQA 1KFXL 1Q6KA 3IMAA 3ZUAA 3H8BA 4DMYA 4X6JA 1IWDA 2DZZA 2ARYA 1PPDA 2H7JA 2VHFA 2C0YA 2E00A 3IEJA 2DJGB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I06 A;  3H7D A;  3BCN A;  3F5V A;  4I04 A;  2AIM A;  2XU4 A;  2AVW A;  2R9N A;  2FTD A;  1MHW A;  4CZW A;  4QRG A;  2HXZ A;  3S3Q A;  1F2C A;  1XKG A;  1PPO A;  2VHS A;  5CVO B;  2AUZ A;  3V6E A;  4P6E A;  1QXP A;  4X6H A;  3RVV A;  5EF4 A;  1DEU A;  1SNK A;  4YV8 A;  3GCB A;  1SP4 B;  2JQG R;  1MDW A;  2XU5 A;  4AXL A;  1GCB A;  3AI8 A;  1NQC A;  2HH5 A;  1CQD A;  1PXV A;  2NQI A;  3B79 A;  3MHS A;  5F02 A;  2HD5 A;  2CB5 A;  2DCB A;  2YJ2 A;  3D6S A;  4WA6 A;  2DC9 A;  4AXM A;  1CV8 A;  1MEG A;  2AUX A;  2NQD B;  1CB5 A;  3HD3 A;  1U5I A;  2DCA A;  3P5X A;  2GFO A;  2GHU A;  1PBH A;  2AYN A;  2IBI A;  1BQI A;  2AU1 A;  2DZY A;  3MHH A;  2DC7 A;  1KFU L;  3ERV A;  1X9Y A;  4YYU A;  1U9W A;  2BDZ A;  4HWY A;  4XR7 A;  1AU4 A;  1VJV A;  3IOQ A;  1ICF A;  1GLO A;  1ZIV A;  4BS6 A;  1ATK A;  4XUI A;  2ACT A;  1AYU A;  1BY8 A;  3HHA A;  3MOR A;  5FPW A;  2O6X A;  2FQ9 A;  2DC8 A;  1EWM A;  1AU3 A;  1KHQ A;  4N79 A;  3NHE A;  3KFQ A;  4QBB A;  2DCC A;  1ME3 A;  2PAD A;  4P6G A;  4QRV A;  3M99 A;  2Y6E A;  3P5V A;  1U9V A;  5K16 A;  2AS8 A;  1AYW A;  3PNR A;  8PCH A;  1NB5 A;  1F2A A;  4G54 A;  3H89 A;  5CHV A;  1CSB B;  4W5C A;  5A24 A;  1ME4 A;  3IHP A;  2DJF B;  4CDF B;  1MEM A;  2JQF R;  1MIR A;  3BWK A;  3H6S A;  2YJB A;  3KWZ A;  4W4U A;  1NL6 A;  1NB3 A;  2PRE A;  4N4Z A;  3IV2 A;  4QH6 A;  1AYV A;  3N3G A;  3WXG A;  3LFY A;  3U8E A;  2HHN A;  1PPP A;  2FRA A;  1AEC A;  4MZO A;  1BGO A;  1PPN A;  4FK5 A;  6PAD A;  1EF7 A;  7PCK A;  4I07 A;  1QOL A;  2YJ8 A;  1YK7 A;  1A6R A;  1NLJ A;  1HUC B;  1M6D A;  3RVX A;  4CDC B;  1GEC E;  4OEM A;  3V6C A;  4N8W A;  4BSQ A;  3O0U A;  3P5W A;  2XU3 A;  2G6D A;  2BDL A;  3K24 A;  3PBH A;  2NQG A;  2DCD A;  2R9O A;  2AYO A;  2OUL A;  1YT7 A;  4Q8G A;  3I3T A;  4PI3 A;  3MTN A;  1KXR A;  1MS6 A;  3KKU A;  3WXF A;  1POP A;  3USV A;  3N4C A;  4DMX A;  3QT4 A;  2OZ2 A;  1K3B B;  2YJC A;  4CDD B;  1TLO A;  1F2B A;  4RY2 A;  3BPM A;  3HWN A;  1Y4H A;  2XU1 A;  2R9C A;  4K7C A;  1STF E;  3KSE A;  4YYS A;  1EWP A;  2P86 A;  3BPF A;  5JH3 A;  2G8J A;  4YYW A;  2R9M A;  2P7U A;  4X6I A;  3K8U A;  1AU2 A;  3TNX A;  2E03 A;  3N3K A;  3LXS A;  4YYQ A;  3E1Z B;  1PAD A;  3H8C A;  2FT2 A;  3OF9 A;  2IPP B;  1DF0 A;  1CTE A;  3KX1 A;  4I05 A;  4PAD A;  2G7Y A;  3OF8 A;  4FIP A;  2PBH A;  3C9E A;  5PAD A;  2R9F A;  9PAP A;  5JA7 A;  3CH2 X;  2ATO A;  5CVN B;  3KW9 A;  3HHI A;  1THE A;  2WBF X;  2G8E A;  3OVX A;  1QMY A;  2E02 A;  2E01 A;  4QRX A;  4YYV A;  3WXE A;  3CBK A;  3DF0 A;  1ZCM A;  4W5B A;  1KHP A;  2PNS A;  4FJC A;  3RVW A;  5CVM A;  1CJL A;  4PP1 A;  1O0E A;  4Q8H A;  3CH3 X;  3BOW A;  3K9M A;  4BQV A;  3QJ3 A;  2P0R A;  3IUT A;  4KLB A;  1JQP A;  1CS8 A;  1AU0 A;  1PE6 A;  4BS5 A;  2F1G A;  2F7D A;  3QSD A;  1TU6 A;  3O1G A;  4ZUX U;  2OP3 A;  2FUD A;  1FH0 A;  1BP4 A;  4YVA A;  3S3R A;  1U9Q X;  4PP2 E;  3F75 A;  4YYR A;  4CDE B;  1EWL A;  5CHT A;  1ITO A;  1Y08 A;  1PCI A;  5J94 A;  3CBJ A;  3PW3 A;  1GMY A;  1AIM A;  1F29 A;  1PIP A;  2R6N A;  1TL9 A;  4BPV A;  3BC3 A;  3OVZ A;  1NPZ A;  3OIS A;  2B1N A;  2FO5 A;  2Y5B A;  1YAL A;  2YJ9 A;  3KWB X;  2FYE A;  4OEL A;  1CPJ A;  5EGW A;  2NQA A;  3PDF A;  2CIO A;  1YK8 A;  2B1M A;  2FRQ A;  1EWO A;  3P5U A;  2DC6 A;  1VSN A;  4MZS A;  1CVZ A;  1U9X A;  1S4V A;  4MSX A;  1YVB A;  1QDQ A;  1KFX L;  1Q6K A;  3IMA A;  3ZUA A;  3H8B A;  4DMY A;  4X6J A;  1IWD A;  2DZZ A;  2ARY A;  1PPD A;  2H7J A;  2VHF A;  2C0Y A;  2E00 A;  3IEJ A;  2DJG B; 
#chains in the Genus database with same CATH topology
 3I06 A;  3H7D A;  3BCN A;  3F5V A;  4I04 A;  2AIM A;  4A5U A;  2XU4 A;  2AVW A;  2R9N A;  2FTD A;  1MHW A;  4CZW A;  4QRG A;  2HXZ A;  3S3Q A;  1F2C A;  1XKG A;  1PPO A;  2VHS A;  5CVO B;  2AUZ A;  4MI7 A;  3V6E A;  4P6E A;  1QXP A;  4X6H A;  3RVV A;  5EF4 A;  1DEU A;  3BB7 A;  1SNK A;  4YV8 A;  3GCB A;  1SP4 B;  5JZE A;  3W31 A;  2JQG R;  1MDW A;  2HWK A;  2XU5 A;  4AXL A;  1GCB A;  3AI8 A;  1NQC A;  2HH5 A;  1CQD A;  1PXV A;  2NQI A;  3B79 A;  4PT5 A;  3MHS A;  4RNA A;  5F02 A;  2HD5 A;  2CB5 A;  2DCB A;  2YJ2 A;  4WUR A;  4MM3 B;  3D6S A;  4WA6 A;  3C0R A;  2DC9 A;  4AXM A;  1CV8 A;  1MEG A;  2AUX A;  2BTW A;  2NQD B;  1CB5 A;  3HD3 A;  1U5I A;  2DCA A;  3TRK A;  3P5X A;  2GFO A;  2GHU A;  1PBH A;  3MTV A;  2AYN A;  2IBI A;  1BQI A;  2AU1 A;  2DZY A;  3MHH A;  2DC7 A;  1KFU L;  4OVZ B;  3ERV A;  4BOP A;  1X9Y A;  4YYU A;  1U9W A;  2BDZ A;  4HWY A;  4XR7 A;  1AU4 A;  1VJV A;  3IOQ A;  1ICF A;  4D8I A;  1GLO A;  1ZIV A;  2FE8 A;  4BS6 A;  1ATK A;  4XUI A;  2ACT A;  1AYU A;  1BY8 A;  3HHA A;  3MOR A;  5FPW A;  2O6X A;  2FQ9 A;  2DC8 A;  1EWM A;  3O65 A;  3PT2 A;  1AU3 A;  1KHQ A;  4N79 A;  3NHE A;  3KFQ A;  2JTC A;  4QBB A;  2DCC A;  1ME3 A;  2PAD A;  4P6G A;  4QRV A;  3M99 A;  2JRI A;  2Y6E A;  3P5V A;  1U9V A;  5K16 A;  2J7Q C;  2AS8 A;  1AYW A;  3PNR A;  8PCH A;  1NB5 A;  3B21 A;  1F2A A;  4G54 A;  3H89 A;  4GUA A;  5CHV A;  1CSB B;  4W5C A;  4OW0 A;  5A24 A;  1UKF A;  1ME4 A;  3IHP A;  2DJF B;  4CDF B;  1MEM A;  2JQF R;  1MIR A;  3BWK A;  3H6S A;  2YJB A;  3KWZ A;  4W4U A;  1NL6 A;  1NB3 A;  2PRE A;  4N4Z A;  3IV2 A;  4QH6 A;  1AYV A;  3N3G A;  3WXG A;  3LFY A;  3U8E A;  2HHN A;  1PPP A;  2FRA A;  1AEC A;  4MZO A;  1BGO A;  1PPN A;  4FK5 A;  6PAD A;  1EF7 A;  7PCK A;  4I07 A;  1QOL A;  2YJ8 A;  1YK7 A;  1A6R A;  1NLJ A;  3MJ5 A;  1HUC B;  1M6D A;  3RVX A;  4CDC B;  1GEC E;  4OEM A;  3V6C A;  4N8W A;  4BSQ A;  4XZX A;  2BU3 A;  3O0U A;  3P5W A;  4D8B A;  2XU3 A;  2G6D A;  2BDL A;  3K24 A;  3PBH A;  2NQG A;  4P16 A;  2DCD A;  2R9O A;  2AYO A;  2OUL A;  1YT7 A;  4Q8G A;  3I3T A;  4PI3 A;  4ZTB A;  3MTN A;  1KXR A;  1MS6 A;  3KKU A;  3WXF A;  1POP A;  3USV A;  3N4C A;  4DMX A;  3QT4 A;  2OZ2 A;  3PHW A;  1K3B B;  2YJC A;  4CDD B;  3IFU A;  4OVZ A;  1TLO A;  1F2B A;  5EZQ A;  4RY2 A;  3BPM A;  3PRM A;  3HWN A;  1Y4H A;  2XU1 A;  2R9C A;  4K7C A;  1STF E;  3KSE A;  4YYS A;  1EWP A;  2P86 A;  3RNV A;  4D8E A;  3BPF A;  5JH3 A;  2G8J A;  4YYW A;  2R9M A;  2P7U A;  4X6I A;  3PHX A;  3K8U A;  1AU2 A;  3TNX A;  2DOS A;  2E03 A;  3BY4 A;  3N3K A;  3LXS A;  4YYQ A;  3E1Z B;  1PAD A;  3H8C A;  4M0W A;  2FT2 A;  3OF9 A;  2IPP B;  1DF0 A;  3TMP A;  1CTE A;  1PVJ A;  3KX1 A;  4I05 A;  4PAD A;  2G7Y A;  3OF8 A;  4FIP A;  2PBH A;  3C9E A;  5PAD A;  2R9F A;  3W30 A;  9PAP A;  5JA7 A;  4IP3 A;  3CH2 X;  2ATO A;  5CVN B;  3KW9 A;  3HHI A;  3PSE A;  4BOQ A;  1THE A;  2WBF X;  2G8E A;  3OVX A;  1QMY A;  2E02 A;  2Z84 A;  2E01 A;  4QRX A;  4YYV A;  3WXE A;  3CBK A;  1YZB A;  3DF0 A;  1ZCM A;  4W5B A;  1KHP A;  2PNS A;  3PHU A;  4FJC A;  3RVW A;  5CVM A;  1CJL A;  2UZJ A;  4PP1 A;  4BOS A;  1O0E A;  4Q8H A;  3CH3 X;  5E6J A;  3BOW A;  3K9M A;  4REZ A;  4BQV A;  3QJ3 A;  2P0R A;  4R3D A;  1DKI A;  3IUT A;  4KLB A;  1JQP A;  1CS8 A;  1AU0 A;  1PE6 A;  4BS5 A;  2F1G A;  2F7D A;  3QSD A;  1TU6 A;  3O1G A;  4BOZ A;  4ZUX U;  2OP3 A;  2FUD A;  1FH0 A;  1BP4 A;  4YVA A;  2J7Q A;  3S3R A;  5KO3 A;  1U9Q X;  4PP2 E;  3F75 A;  4YYR A;  4CDE B;  2BTW B;  4RF0 A;  1EWL A;  5CHT A;  1ITO A;  1Y08 A;  1PCI A;  5J94 A;  3CBJ A;  3PW3 A;  1GMY A;  1AIM A;  1F29 A;  2AGA A;  4HXD B;  1PIP A;  2R6N A;  1TL9 A;  4BPV A;  3BC3 A;  3OVZ A;  1NPZ A;  3OIS A;  2B1N A;  3PRP A;  2FO5 A;  2Y5B A;  1YAL A;  2YJ9 A;  3KWB X;  2FYE A;  4OEL A;  1CPJ A;  5EGW A;  2NQA A;  4BOU A;  3PDF A;  4IUM A;  2CIO A;  1YK8 A;  3OQC A;  2B1M A;  5EZS A;  2FRQ A;  3BBA A;  1EWO A;  3P5U A;  3E9S A;  2DC6 A;  1VSN A;  4RF1 A;  4MZS A;  1CVZ A;  1U9X A;  1S4V A;  3MP2 A;  4MSX A;  1YVB A;  1QDQ A;  1KFX L;  1Q6K A;  3IMA A;  3ZUA A;  3H8B A;  4DMY A;  4X6J A;  1IWD A;  2DZZ A;  2ARY A;  1PPD A;  4RKX A;  2H7J A;  3ZNH A;  2VHF A;  2C0Y A;  2E00 A;  3IEJ A;  2DJG B; 
#chains in the Genus database with same CATH homology
 3I06 A;  3H7D A;  3BCN A;  3F5V A;  4I04 A;  2AIM A;  2XU4 A;  2AVW A;  2R9N A;  2FTD A;  1MHW A;  4CZW A;  4QRG A;  2HXZ A;  2VFC A;  3S3Q A;  1F2C A;  1XKG A;  1PPO A;  2VHS A;  5CVO B;  2AUZ A;  3V6E A;  4P6E A;  1QXP A;  4X6H A;  3RVV A;  1W5R A;  1W4T A;  5EF4 A;  1DEU A;  1SNK A;  4YV8 A;  1E2T A;  3GCB A;  1SP4 B;  2JQG R;  1MDW A;  2XU5 A;  4AXL A;  1GCB A;  3AI8 A;  1NQC A;  2HH5 A;  1CQD A;  1PXV A;  2NQI A;  3B79 A;  3MHS A;  5F02 A;  2HD5 A;  2CB5 A;  2DCB A;  2YJ2 A;  3D6S A;  4WA6 A;  2DC9 A;  4AXM A;  1CV8 A;  1MEG A;  2AUX A;  2NQD B;  1CB5 A;  3HD3 A;  1U5I A;  1W6F A;  2DCA A;  3P5X A;  2GFO A;  2GHU A;  1PBH A;  2AYN A;  2IBI A;  1BQI A;  2AU1 A;  2DZY A;  3MHH A;  2DC7 A;  1KFU L;  3ERV A;  1X9Y A;  4YYU A;  1U9W A;  2BDZ A;  4HWY A;  4XR7 A;  1AU4 A;  1VJV A;  3IOQ A;  1ICF A;  1GLO A;  1ZIV A;  4BS6 A;  1ATK A;  4XUI A;  2ACT A;  1AYU A;  1BY8 A;  3HHA A;  3MOR A;  5FPW A;  2O6X A;  2FQ9 A;  2DC8 A;  1EWM A;  1AU3 A;  1KHQ A;  4N79 A;  3NHE A;  3KFQ A;  4QBB A;  2DCC A;  1ME3 A;  2PAD A;  4P6G A;  4QRV A;  3M99 A;  2Y6E A;  3P5V A;  1U9V A;  5K16 A;  2AS8 A;  1AYW A;  3PNR A;  8PCH A;  1NB5 A;  1F2A A;  4G54 A;  3H89 A;  5CHV A;  1CSB B;  4W5C A;  5A24 A;  1ME4 A;  3IHP A;  2DJF B;  4CDF B;  3D9W A;  1MEM A;  2JQF R;  1MIR A;  3BWK A;  3H6S A;  2YJB A;  3KWZ A;  4W4U A;  1NL6 A;  1NB3 A;  2PRE A;  4N4Z A;  3IV2 A;  4QH6 A;  1AYV A;  3N3G A;  3WXG A;  3LFY A;  3U8E A;  2HHN A;  1PPP A;  2FRA A;  1AEC A;  4MZO A;  1BGO A;  1PPN A;  4FK5 A;  6PAD A;  1EF7 A;  7PCK A;  4I07 A;  1QOL A;  2YJ8 A;  1YK7 A;  1A6R A;  1NLJ A;  1HUC B;  1M6D A;  3RVX A;  4CDC B;  1GEC E;  4OEM A;  3V6C A;  4N8W A;  4BSQ A;  3O0U A;  3P5W A;  2XU3 A;  2G6D A;  2BDL A;  3K24 A;  3PBH A;  2NQG A;  2DCD A;  2R9O A;  2AYO A;  2OUL A;  1YT7 A;  4Q8G A;  3I3T A;  4GUZ A;  4PI3 A;  3MTN A;  1KXR A;  1MS6 A;  3KKU A;  3WXF A;  1POP A;  3USV A;  3N4C A;  4DMX A;  3QT4 A;  4NV7 A;  2OZ2 A;  4C5P A;  4NV8 A;  1K3B B;  2YJC A;  4CDD B;  1TLO A;  1F2B A;  4RY2 A;  1GX3 A;  3BPM A;  4BGF A;  3HWN A;  1Y4H A;  2XU1 A;  2R9C A;  4K7C A;  1STF E;  3KSE A;  4YYS A;  1EWP A;  2VFB A;  2P86 A;  3BPF A;  5JH3 A;  2G8J A;  4YYW A;  2R9M A;  2P7U A;  4X6I A;  3K8U A;  1AU2 A;  3TNX A;  2E03 A;  3N3K A;  3LXS A;  4YYQ A;  3E1Z B;  1PAD A;  3H8C A;  2FT2 A;  3OF9 A;  2IPP B;  1DF0 A;  1CTE A;  2BSZ A;  3KX1 A;  4I05 A;  4PAD A;  2G7Y A;  3OF8 A;  4FIP A;  2PBH A;  3C9E A;  5PAD A;  2R9F A;  9PAP A;  5JA7 A;  3CH2 X;  2ATO A;  5CVN B;  3KW9 A;  3HHI A;  1THE A;  2WBF X;  2G8E A;  3OVX A;  1QMY A;  2E02 A;  2E01 A;  4QRX A;  4YYV A;  3WXE A;  3CBK A;  3DF0 A;  1ZCM A;  4W5B A;  1KHP A;  2PNS A;  4FJC A;  3RVW A;  5CVM A;  1CJL A;  4PP1 A;  3LTW A;  1O0E A;  4Q8H A;  3CH3 X;  3BOW A;  3K9M A;  4BQV A;  3QJ3 A;  2P0R A;  3IUT A;  4KLB A;  1JQP A;  1CS8 A;  1AU0 A;  1PE6 A;  4BS5 A;  2F1G A;  2F7D A;  3QSD A;  1TU6 A;  3O1G A;  4ZUX U;  2OP3 A;  2FUD A;  1FH0 A;  1BP4 A;  4YVA A;  3S3R A;  1U9Q X;  4PP2 E;  3F75 A;  4YYR A;  4CDE B;  1EWL A;  5CHT A;  1ITO A;  1Y08 A;  1PCI A;  5J94 A;  3CBJ A;  3PW3 A;  1GMY A;  1AIM A;  1F29 A;  1PIP A;  2R6N A;  1TL9 A;  4BPV A;  3BC3 A;  3OVZ A;  1NPZ A;  3OIS A;  2B1N A;  2FO5 A;  2Y5B A;  1YAL A;  2YJ9 A;  3KWB X;  2FYE A;  4OEL A;  1CPJ A;  5EGW A;  2NQA A;  3PDF A;  2CIO A;  1YK8 A;  2B1M A;  2FRQ A;  4B55 A;  1EWO A;  3P5U A;  2DC6 A;  1VSN A;  4MZS A;  1CVZ A;  1U9X A;  1S4V A;  4MSX A;  1YVB A;  1QDQ A;  1KFX L;  1Q6K A;  3IMA A;  3ZUA A;  3H8B A;  4DMY A;  4X6J A;  1IWD A;  2DZZ A;  2ARY A;  1PPD A;  2H7J A;  2VHF A;  2C0Y A;  2E00 A;  3IEJ A;  2DJG B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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