2YJ8A

Cathepsin l with a nitrile inhibitor
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
220
structure length
219
Chain Sequence
APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTSDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords CATHEPSIN L1
publication title Halogen Bonding at the Active Sites of Human Cathepsin L and Mek1 Kinase: Efficient Interactions in Different Environments.
pubmed doi rcsb
source organism Homo sapiens
total genus 71
structure length 219
sequence length 220
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2011-05-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2yj8A00
2R9FA 5CVOB 3LFYA 2DC8A 1CQDA 1GLOA 1F29A 1U9QX 1U9WA 5EGWA 1AYVA 2WBFX 2HHNA 3KKUA 2AIMA 3V6CA 1KHPA 2Y5BA 5CVNB 1MEMA 5CHTA 4BQVA 4I04A 2DC6A 2PBHA 1PADA 2DZYA 3N4CA 2Y6EA 1PXVA 3H8CA 2IBIA 3QSDA 3K8UA 1CB5A 3OVXA 2R9MA 2VHFA 2O6XA 3DF0A 4N4ZA 3QT4A 3D6SA 1AU2A 4FK5A 5JH3A 2DCAA 3P5WA 4K7CA 2FRQA 1THEA 1F2BA 1MEGA 1NB3A 1PCIA 5EF4A 2HH5A 1KHQA 2E01A 4KLBA 2ARYA 1QXPA 1ZCMA 4WA6A 2E00A 2YJ2A 3KWZA 2E03A 2JQFR 1A6RA 2AUXA 1PE6A 1EWLA 5JA7A 4YV8A 2R6NA 3LXSA 4RY2A 1CPJA 1PIPA 1YALA 3OISA 2NQIA 4N79A 1AECA 4QH6A 2NQDB 2GHUA 2BDLA 1Q6KA 2F1GA 1U5IA 4CDDB 1NLJA 2H7JA 2FQ9A 4BS5A 1VJVA 3WXEA 5F02A 6PADA 2DCCA 2IPPB 1YK8A 1EWMA 1U9XA 1O0EA 1TU6A 4XUIA 1HUCB 2DC7A 2XU3A 3IMAA 1AU4A 1FH0A 3MTNA 5A24A 2R9NA 3PDFA 3IV2A 2FO5A 2YJ9A 3QJ3A 4FIPA 4MZSA 4OEMA 3F5VA 3B79A 1GMYA 3O0UA 4QRVA 1NPZA 4W5BA 1Y08A 2YJCA 3IHPA 3S3QA 4YYQA 2NQGA 3IUTA 1KFUL 2E02A 2OULA 4CDCB 3CH2X 1NB5A 1STFE 1POPA 2VHSA 1EWPA 2FRAA 1AIMA 4CZWA 2NQAA 3ZUAA 2XU1A 4PP1A 4AXMA 5K16A 1IWDA 4P6GA 3F75A 3BPFA 1MHWA 1SNKA 1PPNA 4CDFB 8PCHA 5J94A 4X6HA 4I07A 1GCBA 2R9CA 2FT2A 2AU1A 3HWNA 3GCBA 5CHVA 1DEUA 3HHIA 2JQGR 3PNRA 3H8BA 2FUDA 3N3KA 1AU3A 1YT7A 4DMXA 1M6DA 2ATOA 2C0YA 3ERVA 1NQCA 4I05A 2DZZA 3KSEA 2XU5A 4YYUA 1ME4A 4FJCA 3PW3A 4QBBA 2GFOA 3HD3A 2R9OA 1Y4HA 1F2AA 2P7UA 3WXFA 1EF7A 3CBJA 2DJGB 4PADA 4BS6A 3BWKA 3BPMA 2DC9A 2CIOA 4YYSA 1NL6A 2XU4A 2HD5A 3MHSA 2G8EA 3I3TA 4YYRA 2AVWA 1MDWA 3C9EA 2AUZA 2DJFB 1QOLA 4X6IA 7PCKA 4YYWA 3H89A 2DCBA 1EWOA 4PI3A 1MIRA 4HWYA 2B1NA 2B1MA 1QDQA 2F7DA 2P0RA 4Q8GA 1ATKA 1X9YA 2PADA 4QRXA 3OF8A 1JQPA 3RVWA 3TNXA 2G7YA 1XKGA 1BY8A 1F2CA 3IOQA 3BOWA 2AYNA 3HHAA 1BGOA 1BP4A 3MHHA 1PPDA 2HXZA 3P5UA 2YJ8A 4OELA 3RVVA 1AYWA 1TLOA 1ICFA 3E1ZB 2PREA 1AYUA 1CVZA 1K3BB 3KX1A 2PNSA 4N8WA 2FYEA 5CVMA 3PBHA 1DF0A 3BCNA 2YJBA 1KFXL 2AS8A 1CTEA 4DMYA 4Q8HA 2OP3A 1MS6A 3OF9A 3H7DA 4W5CA 4YYVA 2CB5A 3K24A 1U9VA 4X6JA 4BPVA 1QMYA 1SP4B 3AI8A 3IEJA 4BSQA 1CS8A 1ME3A 3S3RA 1VSNA 3CBKA 3RVXA 4CDEB 5FPWA 3USVA 4MSXA 1YK7A 1TL9A 3K9MA 1CSBB 1KXRA 3CH3X 2ACTA 1PBHA 4QRGA 1PPOA 3M99A 3OVZA 4PP2E 3KW9A 9PAPA 1PPPA 1AU0A 3NHEA 3U8EA 2DCDA 3KWBX 3P5XA 4AXLA 2G6DA 2OZ2A 2FTDA 1YVBA 3I06A 3O1GA 3KFQA 3WXGA 3MORA 4P6EA 1S4VA 2AYOA 3BC3A 5PADA 4YVAA 3N3GA 3P5VA 2G8JA 1ITOA 2P86A 2BDZA 4MZOA 4G54A 1CV8A 1BQIA 1GECE 3H6SA 4W4UA 3V6EA 1ZIVA 4ZUXU 4XR7A 1CJLA
chains in the Genus database with same CATH superfamily
2R9FA 5CVOB 3LFYA 3BB7A 2DC8A 1CQDA 1GLOA 1F29A 1U9QX 4OW0A 1U9WA 5EGWA 1AYVA 2WBFX 2HHNA 3KKUA 2AIMA 4GUAA 3V6CA 1KHPA 2Y5BA 5CVNB 1MEMA 5CHTA 4BQVA 4I04A 2DC6A 2PBHA 1PADA 2DZYA 3N4CA 2Y6EA 1PXVA 3H8CA 2IBIA 3QSDA 3E9SA 3K8UA 1CB5A 3OVXA 2R9MA 2VHFA 2O6XA 3DF0A 3OQCA 3QT4A 4N4ZA 3D6SA 1AU2A 4FK5A 5JH3A 2DCAA 3P5WA 4K7CA 2FRQA 1THEA 1F2BA 1MEGA 1NB3A 1PCIA 5EF4A 2HH5A 1KHQA 2E01A 4KLBA 2ARYA 1QXPA 1ZCMA 4WA6A 2E00A 2YJ2A 3KWZA 2E03A 2JQFR 1A6RA 2AUXA 1PE6A 1EWLA 5JA7A 4YV8A 3W30A 2R6NA 3LXSA 1PVJA 4RY2A 1CPJA 1PIPA 3B21A 1YALA 3OISA 2NQIA 4N79A 1AECA 4QH6A 2NQDB 2GHUA 2BDLA 2HWKA 1Q6KA 2F1GA 1U5IA 2BU3A 4CDDB 1NLJA 2H7JA 2FQ9A 4BS5A 2AGAA 1VJVA 3WXEA 5F02A 6PADA 2DCCA 2IPPB 1YK8A 1EWMA 1U9XA 1O0EA 1TU6A 4XUIA 1HUCB 2DC7A 2XU3A 3IMAA 1AU4A 1FH0A 5EZSA 3MTNA 5A24A 2R9NA 4BOSA 3PDFA 3IV2A 2FO5A 2YJ9A 3QJ3A 4FIPA 4MZSA 4OEMA 3F5VA 3B79A 2UZJA 1GMYA 3O0UA 4QRVA 1NPZA 4W5BA 1Y08A 2YJCA 3IHPA 3S3QA 4YYQA 2NQGA 3IUTA 1KFUL 2BTWB 2BTWA 4R3DA 2E02A 2OULA 5E6JA 3CH2X 4CDCB 1NB5A 1STFE 4M0WA 1POPA 2VHSA 1EWPA 2FRAA 1AIMA 3RNVA 4CZWA 4BOUA 2NQAA 3ZUAA 1DKIA 2XU1A 4PP1A 4AXMA 3PT2A 5K16A 1IWDA 4P6GA 3F75A 3BPFA 4D8IA 3PHUA 3MTVA 4BOPA 1MHWA 1SNKA 4P16A 1PPNA 4BOQA 4CDFB 8PCHA 5J94A 4X6HA 4A5UA 4I07A 1GCBA 2R9CA 2FT2A 2AU1A 4MM3B 3HWNA 3GCBA 5CHVA 1DEUA 3HHIA 2JQGR 3PNRA 3H8BA 2FUDA 3N3KA 1AU3A 1YT7A 4IP3A 4DMXA 1M6DA 2ATOA 2C0YA 3ERVA 1NQCA 4I05A 2DZZA 3KSEA 2XU5A 4YYUA 1ME4A 4FJCA 3PW3A 4BOZA 4QBBA 2GFOA 3HD3A 2R9OA 3BBAA 1Y4HA 1F2AA 2P7UA 3WXFA 4RNAA 1EF7A 3CBJA 2DJGB 4PADA 5EZQA 3BWKA 4BS6A 3BPMA 3C0RA 2DC9A 3TMPA 2CIOA 3IFUA 4YYSA 2JRIA 4PT5A 1NL6A 2XU4A 2HD5A 3MHSA 2G8EA 3I3TA 4RKXA 4YYRA 2AVWA 1MDWA 3C9EA 2AUZA 2DJFB 1QOLA 4X6IA 7PCKA 1YZBA 4YYWA 3H89A 2DCBA 1EWOA 4PI3A 1MIRA 4HWYA 2B1NA 2B1MA 1QDQA 4D8EA 2F7DA 2P0RA 4Q8GA 1ATKA 1X9YA 2PADA 4IUMA 4QRXA 3OF8A 1JQPA 3RVWA 3MP2A 2G7YA 3TNXA 1XKGA 1BY8A 4ZTBA 1F2CA 3IOQA 3PRPA 3BOWA 2AYNA 2J7QA 3HHAA 1BGOA 1BP4A 3MHHA 1PPDA 2HXZA 3P5UA 2YJ8A 4OELA 3RVVA 1AYWA 1TLOA 3PHXA 1ICFA 3E1ZB 2PREA 1AYUA 1CVZA 1K3BB 3KX1A 2PNSA 4N8WA 4XZXA 4RF1A 2FYEA 5CVMA 3PBHA 1DF0A 3BCNA 2YJBA 3MJ5A 1KFXL 2AS8A 1CTEA 4DMYA 4Q8HA 2OP3A 1MS6A 3OF9A 2JTCA 3H7DA 4W5CA 4WURA 4YYVA 2CB5A 1UKFA 3K24A 3ZNHA 1U9VA 4X6JA 4REZA 4BPVA 1QMYA 1SP4B 3AI8A 3IEJA 4BSQA 1CS8A 1ME3A 3S3RA 1VSNA 2FE8A 4MI7A 3CBKA 3BY4A 3RVXA 4CDEB 3TRKA 5FPWA 3USVA 4MSXA 1YK7A 1TL9A 3K9MA 3PSEA 2DOSA 1CSBB 1KXRA 3CH3X 2ACTA 1PBHA 4QRGA 1PPOA 4OVZB 3M99A 3OVZA 4PP2E 3KW9A 4OVZA 9PAPA 1PPPA 1AU0A 3NHEA 3U8EA 2Z84A 2DCDA 3KWBX 3PHWA 3P5XA 2J7QC 4AXLA 4D8BA 2G6DA 2OZ2A 2FTDA 1YVBA 5JZEA 3I06A 3O1GA 3KFQA 3WXGA 3W31A 3MORA 4P6EA 1S4VA 2AYOA 3BC3A 5PADA 4YVAA 5KO3A 4HXDB 3N3GA 3P5VA 2G8JA 1ITOA 2P86A 2BDZA 4MZOA 4G54A 4RF0A 1CV8A 1BQIA 1GECE 3H6SA 3PRMA 4W4UA 3V6EA 1ZIVA 4ZUXU 3O65A 4XR7A 1CJLA
chains in the Genus database with same CATH topology
2R9FA 5CVOB 3LFYA 2DC8A 1CQDA 1GLOA 1F29A 1U9QX 1U9WA 5EGWA 1AYVA 2WBFX 2HHNA 3KKUA 2AIMA 3V6CA 1KHPA 2Y5BA 5CVNB 1MEMA 5CHTA 4BQVA 4I04A 4B55A 2DC6A 2PBHA 1PADA 2DZYA 3N4CA 2Y6EA 1PXVA 3H8CA 2IBIA 3QSDA 3K8UA 1CB5A 3OVXA 2R9MA 2VHFA 2O6XA 3DF0A 4N4ZA 3QT4A 3D9WA 3D6SA 1AU2A 4FK5A 3LTWA 5JH3A 2DCAA 3P5WA 4K7CA 2FRQA 1THEA 1F2BA 1MEGA 1NB3A 1PCIA 5EF4A 2HH5A 1KHQA 2E01A 4KLBA 2ARYA 1QXPA 1ZCMA 4WA6A 2E00A 2YJ2A 1W5RA 3KWZA 2E03A 2JQFR 1A6RA 2AUXA 1PE6A 1EWLA 5JA7A 2BSZA 4YV8A 2R6NA 3LXSA 4RY2A 1CPJA 1PIPA 1YALA 3OISA 2NQIA 2VFCA 4N79A 1AECA 4QH6A 2NQDB 2GHUA 2BDLA 1Q6KA 2F1GA 1U5IA 4CDDB 1NLJA 2H7JA 2FQ9A 4BS5A 1VJVA 3WXEA 2VFBA 5F02A 6PADA 2DCCA 2IPPB 1YK8A 1EWMA 1U9XA 1O0EA 1TU6A 4XUIA 1HUCB 2DC7A 2XU3A 3IMAA 1AU4A 1FH0A 3MTNA 5A24A 2R9NA 3PDFA 3IV2A 2FO5A 2YJ9A 3QJ3A 4FIPA 4MZSA 4OEMA 3F5VA 3B79A 1GMYA 3O0UA 4QRVA 1NPZA 4W5BA 1Y08A 2YJCA 3IHPA 3S3QA 4YYQA 2NQGA 3IUTA 1KFUL 2E02A 2OULA 4CDCB 3CH2X 1NB5A 1STFE 1POPA 2VHSA 1EWPA 2FRAA 1AIMA 1W6FA 4CZWA 2NQAA 3ZUAA 2XU1A 4PP1A 4AXMA 5K16A 1IWDA 4P6GA 3F75A 3BPFA 1MHWA 1SNKA 1PPNA 4CDFB 8PCHA 1E2TA 5J94A 4X6HA 4I07A 1GCBA 2R9CA 2FT2A 2AU1A 3HWNA 3GCBA 5CHVA 4NV8A 1GX3A 1DEUA 4C5PA 3HHIA 2JQGR 3PNRA 3H8BA 2FUDA 3N3KA 1AU3A 1YT7A 1W4TA 4DMXA 1M6DA 2ATOA 2C0YA 3ERVA 1NQCA 4I05A 2DZZA 3KSEA 2XU5A 4YYUA 1ME4A 4FJCA 3PW3A 4QBBA 2GFOA 3HD3A 4NV7A 2R9OA 1Y4HA 1F2AA 2P7UA 3WXFA 1EF7A 3CBJA 2DJGB 4PADA 4BS6A 3BWKA 3BPMA 2DC9A 2CIOA 4YYSA 1NL6A 2XU4A 2HD5A 3MHSA 2G8EA 3I3TA 4YYRA 2AVWA 1MDWA 3C9EA 2AUZA 2DJFB 1QOLA 4X6IA 7PCKA 4YYWA 3H89A 2DCBA 1EWOA 4PI3A 1MIRA 4HWYA 2B1NA 2B1MA 1QDQA 2F7DA 2P0RA 4Q8GA 1ATKA 1X9YA 2PADA 4QRXA 3OF8A 1JQPA 3RVWA 3TNXA 2G7YA 1XKGA 1BY8A 1F2CA 3IOQA 3BOWA 2AYNA 3HHAA 1BGOA 1BP4A 3MHHA 1PPDA 2HXZA 3P5UA 4BGFA 2YJ8A 4OELA 3RVVA 1AYWA 1TLOA 1ICFA 3E1ZB 2PREA 1AYUA 1CVZA 1K3BB 3KX1A 2PNSA 4N8WA 2FYEA 5CVMA 3PBHA 1DF0A 3BCNA 2YJBA 1KFXL 2AS8A 1CTEA 4DMYA 4Q8HA 2OP3A 1MS6A 3OF9A 3H7DA 4W5CA 4YYVA 2CB5A 3K24A 1U9VA 4X6JA 4BPVA 1QMYA 1SP4B 3AI8A 3IEJA 4BSQA 1CS8A 1ME3A 3S3RA 1VSNA 3CBKA 3RVXA 4CDEB 5FPWA 3USVA 4GUZA 4MSXA 1YK7A 1TL9A 3K9MA 1CSBB 1KXRA 3CH3X 2ACTA 1PBHA 4QRGA 1PPOA 3M99A 3OVZA 4PP2E 3KW9A 9PAPA 1PPPA 1AU0A 3NHEA 3U8EA 2DCDA 3KWBX 3P5XA 4AXLA 2G6DA 2OZ2A 2FTDA 1YVBA 3I06A 3O1GA 3KFQA 3WXGA 3MORA 4P6EA 1S4VA 2AYOA 3BC3A 5PADA 4YVAA 3N3GA 3P5VA 2G8JA 1ITOA 2P86A 2BDZA 4MZOA 4G54A 1CV8A 1BQIA 1GECE 3H6SA 4W4UA 3V6EA 1ZIVA 4ZUXU 4XR7A 1CJLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2R9F A;  5CVO B;  3LFY A;  2DC8 A;  1CQD A;  1GLO A;  1F29 A;  1U9Q X;  1U9W A;  5EGW A;  1AYV A;  2WBF X;  2HHN A;  3KKU A;  2AIM A;  3V6C A;  1KHP A;  2Y5B A;  5CVN B;  1MEM A;  5CHT A;  4BQV A;  4I04 A;  2DC6 A;  2PBH A;  1PAD A;  2DZY A;  3N4C A;  2Y6E A;  1PXV A;  3H8C A;  2IBI A;  3QSD A;  3K8U A;  1CB5 A;  3OVX A;  2R9M A;  2VHF A;  2O6X A;  3DF0 A;  4N4Z A;  3QT4 A;  3D6S A;  1AU2 A;  4FK5 A;  5JH3 A;  2DCA A;  3P5W A;  4K7C A;  2FRQ A;  1THE A;  1F2B A;  1MEG A;  1NB3 A;  1PCI A;  5EF4 A;  2HH5 A;  1KHQ A;  2E01 A;  4KLB A;  2ARY A;  1QXP A;  1ZCM A;  4WA6 A;  2E00 A;  2YJ2 A;  3KWZ A;  2E03 A;  2JQF R;  1A6R A;  2AUX A;  1PE6 A;  1EWL A;  5JA7 A;  4YV8 A;  2R6N A;  3LXS A;  4RY2 A;  1CPJ A;  1PIP A;  1YAL A;  3OIS A;  2NQI A;  4N79 A;  1AEC A;  4QH6 A;  2NQD B;  2GHU A;  2BDL A;  1Q6K A;  2F1G A;  1U5I A;  4CDD B;  1NLJ A;  2H7J A;  2FQ9 A;  4BS5 A;  1VJV A;  3WXE A;  5F02 A;  6PAD A;  2DCC A;  2IPP B;  1YK8 A;  1EWM A;  1U9X A;  1O0E A;  1TU6 A;  4XUI A;  1HUC B;  2DC7 A;  2XU3 A;  3IMA A;  1AU4 A;  1FH0 A;  3MTN A;  5A24 A;  2R9N A;  3PDF A;  3IV2 A;  2FO5 A;  2YJ9 A;  3QJ3 A;  4FIP A;  4MZS A;  4OEM A;  3F5V A;  3B79 A;  1GMY A;  3O0U A;  4QRV A;  1NPZ A;  4W5B A;  1Y08 A;  2YJC A;  3IHP A;  3S3Q A;  4YYQ A;  2NQG A;  3IUT A;  1KFU L;  2E02 A;  2OUL A;  4CDC B;  3CH2 X;  1NB5 A;  1STF E;  1POP A;  2VHS A;  1EWP A;  2FRA A;  1AIM A;  4CZW A;  2NQA A;  3ZUA A;  2XU1 A;  4PP1 A;  4AXM A;  5K16 A;  1IWD A;  4P6G A;  3F75 A;  3BPF A;  1MHW A;  1SNK A;  1PPN A;  4CDF B;  8PCH A;  5J94 A;  4X6H A;  4I07 A;  1GCB A;  2R9C A;  2FT2 A;  2AU1 A;  3HWN A;  3GCB A;  5CHV A;  1DEU A;  3HHI A;  2JQG R;  3PNR A;  3H8B A;  2FUD A;  3N3K A;  1AU3 A;  1YT7 A;  4DMX A;  1M6D A;  2ATO A;  2C0Y A;  3ERV A;  1NQC A;  4I05 A;  2DZZ A;  3KSE A;  2XU5 A;  4YYU A;  1ME4 A;  4FJC A;  3PW3 A;  4QBB A;  2GFO A;  3HD3 A;  2R9O A;  1Y4H A;  1F2A A;  2P7U A;  3WXF A;  1EF7 A;  3CBJ A;  2DJG B;  4PAD A;  4BS6 A;  3BWK A;  3BPM A;  2DC9 A;  2CIO A;  4YYS A;  1NL6 A;  2XU4 A;  2HD5 A;  3MHS A;  2G8E A;  3I3T A;  4YYR A;  2AVW A;  1MDW A;  3C9E A;  2AUZ A;  2DJF B;  1QOL A;  4X6I A;  7PCK A;  4YYW A;  3H89 A;  2DCB A;  1EWO A;  4PI3 A;  1MIR A;  4HWY A;  2B1N A;  2B1M A;  1QDQ A;  2F7D A;  2P0R A;  4Q8G A;  1ATK A;  1X9Y A;  2PAD A;  4QRX A;  3OF8 A;  1JQP A;  3RVW A;  3TNX A;  2G7Y A;  1XKG A;  1BY8 A;  1F2C A;  3IOQ A;  3BOW A;  2AYN A;  3HHA A;  1BGO A;  1BP4 A;  3MHH A;  1PPD A;  2HXZ A;  3P5U A;  2YJ8 A;  4OEL A;  3RVV A;  1AYW A;  1TLO A;  1ICF A;  3E1Z B;  2PRE A;  1AYU A;  1CVZ A;  1K3B B;  3KX1 A;  2PNS A;  4N8W A;  2FYE A;  5CVM A;  3PBH A;  1DF0 A;  3BCN A;  2YJB A;  1KFX L;  2AS8 A;  1CTE A;  4DMY A;  4Q8H A;  2OP3 A;  1MS6 A;  3OF9 A;  3H7D A;  4W5C A;  4YYV A;  2CB5 A;  3K24 A;  1U9V A;  4X6J A;  4BPV A;  1QMY A;  1SP4 B;  3AI8 A;  3IEJ A;  4BSQ A;  1CS8 A;  1ME3 A;  3S3R A;  1VSN A;  3CBK A;  3RVX A;  4CDE B;  5FPW A;  3USV A;  4MSX A;  1YK7 A;  1TL9 A;  3K9M A;  1CSB B;  1KXR A;  3CH3 X;  2ACT A;  1PBH A;  4QRG A;  1PPO A;  3M99 A;  3OVZ A;  4PP2 E;  3KW9 A;  9PAP A;  1PPP A;  1AU0 A;  3NHE A;  3U8E A;  2DCD A;  3KWB X;  3P5X A;  4AXL A;  2G6D A;  2OZ2 A;  2FTD A;  1YVB A;  3I06 A;  3O1G A;  3KFQ A;  3WXG A;  3MOR A;  4P6E A;  1S4V A;  2AYO A;  3BC3 A;  5PAD A;  4YVA A;  3N3G A;  3P5V A;  2G8J A;  1ITO A;  2P86 A;  2BDZ A;  4MZO A;  4G54 A;  1CV8 A;  1BQI A;  1GEC E;  3H6S A;  4W4U A;  3V6E A;  1ZIV A;  4ZUX U;  4XR7 A;  1CJL A; 
#chains in the Genus database with same CATH topology
 2R9F A;  5CVO B;  3LFY A;  3BB7 A;  2DC8 A;  1CQD A;  1GLO A;  1F29 A;  1U9Q X;  4OW0 A;  1U9W A;  5EGW A;  1AYV A;  2WBF X;  2HHN A;  3KKU A;  2AIM A;  4GUA A;  3V6C A;  1KHP A;  2Y5B A;  5CVN B;  1MEM A;  5CHT A;  4BQV A;  4I04 A;  2DC6 A;  2PBH A;  1PAD A;  2DZY A;  3N4C A;  2Y6E A;  1PXV A;  3H8C A;  2IBI A;  3QSD A;  3E9S A;  3K8U A;  1CB5 A;  3OVX A;  2R9M A;  2VHF A;  2O6X A;  3DF0 A;  3OQC A;  3QT4 A;  4N4Z A;  3D6S A;  1AU2 A;  4FK5 A;  5JH3 A;  2DCA A;  3P5W A;  4K7C A;  2FRQ A;  1THE A;  1F2B A;  1MEG A;  1NB3 A;  1PCI A;  5EF4 A;  2HH5 A;  1KHQ A;  2E01 A;  4KLB A;  2ARY A;  1QXP A;  1ZCM A;  4WA6 A;  2E00 A;  2YJ2 A;  3KWZ A;  2E03 A;  2JQF R;  1A6R A;  2AUX A;  1PE6 A;  1EWL A;  5JA7 A;  4YV8 A;  3W30 A;  2R6N A;  3LXS A;  1PVJ A;  4RY2 A;  1CPJ A;  1PIP A;  3B21 A;  1YAL A;  3OIS A;  2NQI A;  4N79 A;  1AEC A;  4QH6 A;  2NQD B;  2GHU A;  2BDL A;  2HWK A;  1Q6K A;  2F1G A;  1U5I A;  2BU3 A;  4CDD B;  1NLJ A;  2H7J A;  2FQ9 A;  4BS5 A;  2AGA A;  1VJV A;  3WXE A;  5F02 A;  6PAD A;  2DCC A;  2IPP B;  1YK8 A;  1EWM A;  1U9X A;  1O0E A;  1TU6 A;  4XUI A;  1HUC B;  2DC7 A;  2XU3 A;  3IMA A;  1AU4 A;  1FH0 A;  5EZS A;  3MTN A;  5A24 A;  2R9N A;  4BOS A;  3PDF A;  3IV2 A;  2FO5 A;  2YJ9 A;  3QJ3 A;  4FIP A;  4MZS A;  4OEM A;  3F5V A;  3B79 A;  2UZJ A;  1GMY A;  3O0U A;  4QRV A;  1NPZ A;  4W5B A;  1Y08 A;  2YJC A;  3IHP A;  3S3Q A;  4YYQ A;  2NQG A;  3IUT A;  1KFU L;  2BTW B;  2BTW A;  4R3D A;  2E02 A;  2OUL A;  5E6J A;  3CH2 X;  4CDC B;  1NB5 A;  1STF E;  4M0W A;  1POP A;  2VHS A;  1EWP A;  2FRA A;  1AIM A;  3RNV A;  4CZW A;  4BOU A;  2NQA A;  3ZUA A;  1DKI A;  2XU1 A;  4PP1 A;  4AXM A;  3PT2 A;  5K16 A;  1IWD A;  4P6G A;  3F75 A;  3BPF A;  4D8I A;  3PHU A;  3MTV A;  4BOP A;  1MHW A;  1SNK A;  4P16 A;  1PPN A;  4BOQ A;  4CDF B;  8PCH A;  5J94 A;  4X6H A;  4A5U A;  4I07 A;  1GCB A;  2R9C A;  2FT2 A;  2AU1 A;  4MM3 B;  3HWN A;  3GCB A;  5CHV A;  1DEU A;  3HHI A;  2JQG R;  3PNR A;  3H8B A;  2FUD A;  3N3K A;  1AU3 A;  1YT7 A;  4IP3 A;  4DMX A;  1M6D A;  2ATO A;  2C0Y A;  3ERV A;  1NQC A;  4I05 A;  2DZZ A;  3KSE A;  2XU5 A;  4YYU A;  1ME4 A;  4FJC A;  3PW3 A;  4BOZ A;  4QBB A;  2GFO A;  3HD3 A;  2R9O A;  3BBA A;  1Y4H A;  1F2A A;  2P7U A;  3WXF A;  4RNA A;  1EF7 A;  3CBJ A;  2DJG B;  4PAD A;  5EZQ A;  3BWK A;  4BS6 A;  3BPM A;  3C0R A;  2DC9 A;  3TMP A;  2CIO A;  3IFU A;  4YYS A;  2JRI A;  4PT5 A;  1NL6 A;  2XU4 A;  2HD5 A;  3MHS A;  2G8E A;  3I3T A;  4RKX A;  4YYR A;  2AVW A;  1MDW A;  3C9E A;  2AUZ A;  2DJF B;  1QOL A;  4X6I A;  7PCK A;  1YZB A;  4YYW A;  3H89 A;  2DCB A;  1EWO A;  4PI3 A;  1MIR A;  4HWY A;  2B1N A;  2B1M A;  1QDQ A;  4D8E A;  2F7D A;  2P0R A;  4Q8G A;  1ATK A;  1X9Y A;  2PAD A;  4IUM A;  4QRX A;  3OF8 A;  1JQP A;  3RVW A;  3MP2 A;  2G7Y A;  3TNX A;  1XKG A;  1BY8 A;  4ZTB A;  1F2C A;  3IOQ A;  3PRP A;  3BOW A;  2AYN A;  2J7Q A;  3HHA A;  1BGO A;  1BP4 A;  3MHH A;  1PPD A;  2HXZ A;  3P5U A;  2YJ8 A;  4OEL A;  3RVV A;  1AYW A;  1TLO A;  3PHX A;  1ICF A;  3E1Z B;  2PRE A;  1AYU A;  1CVZ A;  1K3B B;  3KX1 A;  2PNS A;  4N8W A;  4XZX A;  4RF1 A;  2FYE A;  5CVM A;  3PBH A;  1DF0 A;  3BCN A;  2YJB A;  3MJ5 A;  1KFX L;  2AS8 A;  1CTE A;  4DMY A;  4Q8H A;  2OP3 A;  1MS6 A;  3OF9 A;  2JTC A;  3H7D A;  4W5C A;  4WUR A;  4YYV A;  2CB5 A;  1UKF A;  3K24 A;  3ZNH A;  1U9V A;  4X6J A;  4REZ A;  4BPV A;  1QMY A;  1SP4 B;  3AI8 A;  3IEJ A;  4BSQ A;  1CS8 A;  1ME3 A;  3S3R A;  1VSN A;  2FE8 A;  4MI7 A;  3CBK A;  3BY4 A;  3RVX A;  4CDE B;  3TRK A;  5FPW A;  3USV A;  4MSX A;  1YK7 A;  1TL9 A;  3K9M A;  3PSE A;  2DOS A;  1CSB B;  1KXR A;  3CH3 X;  2ACT A;  1PBH A;  4QRG A;  1PPO A;  4OVZ B;  3M99 A;  3OVZ A;  4PP2 E;  3KW9 A;  4OVZ A;  9PAP A;  1PPP A;  1AU0 A;  3NHE A;  3U8E A;  2Z84 A;  2DCD A;  3KWB X;  3PHW A;  3P5X A;  2J7Q C;  4AXL A;  4D8B A;  2G6D A;  2OZ2 A;  2FTD A;  1YVB A;  5JZE A;  3I06 A;  3O1G A;  3KFQ A;  3WXG A;  3W31 A;  3MOR A;  4P6E A;  1S4V A;  2AYO A;  3BC3 A;  5PAD A;  4YVA A;  5KO3 A;  4HXD B;  3N3G A;  3P5V A;  2G8J A;  1ITO A;  2P86 A;  2BDZ A;  4MZO A;  4G54 A;  4RF0 A;  1CV8 A;  1BQI A;  1GEC E;  3H6S A;  3PRM A;  4W4U A;  3V6E A;  1ZIV A;  4ZUX U;  3O65 A;  4XR7 A;  1CJL A; 
#chains in the Genus database with same CATH homology
 2R9F A;  5CVO B;  3LFY A;  2DC8 A;  1CQD A;  1GLO A;  1F29 A;  1U9Q X;  1U9W A;  5EGW A;  1AYV A;  2WBF X;  2HHN A;  3KKU A;  2AIM A;  3V6C A;  1KHP A;  2Y5B A;  5CVN B;  1MEM A;  5CHT A;  4BQV A;  4I04 A;  4B55 A;  2DC6 A;  2PBH A;  1PAD A;  2DZY A;  3N4C A;  2Y6E A;  1PXV A;  3H8C A;  2IBI A;  3QSD A;  3K8U A;  1CB5 A;  3OVX A;  2R9M A;  2VHF A;  2O6X A;  3DF0 A;  4N4Z A;  3QT4 A;  3D9W A;  3D6S A;  1AU2 A;  4FK5 A;  3LTW A;  5JH3 A;  2DCA A;  3P5W A;  4K7C A;  2FRQ A;  1THE A;  1F2B A;  1MEG A;  1NB3 A;  1PCI A;  5EF4 A;  2HH5 A;  1KHQ A;  2E01 A;  4KLB A;  2ARY A;  1QXP A;  1ZCM A;  4WA6 A;  2E00 A;  2YJ2 A;  1W5R A;  3KWZ A;  2E03 A;  2JQF R;  1A6R A;  2AUX A;  1PE6 A;  1EWL A;  5JA7 A;  2BSZ A;  4YV8 A;  2R6N A;  3LXS A;  4RY2 A;  1CPJ A;  1PIP A;  1YAL A;  3OIS A;  2NQI A;  2VFC A;  4N79 A;  1AEC A;  4QH6 A;  2NQD B;  2GHU A;  2BDL A;  1Q6K A;  2F1G A;  1U5I A;  4CDD B;  1NLJ A;  2H7J A;  2FQ9 A;  4BS5 A;  1VJV A;  3WXE A;  2VFB A;  5F02 A;  6PAD A;  2DCC A;  2IPP B;  1YK8 A;  1EWM A;  1U9X A;  1O0E A;  1TU6 A;  4XUI A;  1HUC B;  2DC7 A;  2XU3 A;  3IMA A;  1AU4 A;  1FH0 A;  3MTN A;  5A24 A;  2R9N A;  3PDF A;  3IV2 A;  2FO5 A;  2YJ9 A;  3QJ3 A;  4FIP A;  4MZS A;  4OEM A;  3F5V A;  3B79 A;  1GMY A;  3O0U A;  4QRV A;  1NPZ A;  4W5B A;  1Y08 A;  2YJC A;  3IHP A;  3S3Q A;  4YYQ A;  2NQG A;  3IUT A;  1KFU L;  2E02 A;  2OUL A;  4CDC B;  3CH2 X;  1NB5 A;  1STF E;  1POP A;  2VHS A;  1EWP A;  2FRA A;  1AIM A;  1W6F A;  4CZW A;  2NQA A;  3ZUA A;  2XU1 A;  4PP1 A;  4AXM A;  5K16 A;  1IWD A;  4P6G A;  3F75 A;  3BPF A;  1MHW A;  1SNK A;  1PPN A;  4CDF B;  8PCH A;  1E2T A;  5J94 A;  4X6H A;  4I07 A;  1GCB A;  2R9C A;  2FT2 A;  2AU1 A;  3HWN A;  3GCB A;  5CHV A;  4NV8 A;  1GX3 A;  1DEU A;  4C5P A;  3HHI A;  2JQG R;  3PNR A;  3H8B A;  2FUD A;  3N3K A;  1AU3 A;  1YT7 A;  1W4T A;  4DMX A;  1M6D A;  2ATO A;  2C0Y A;  3ERV A;  1NQC A;  4I05 A;  2DZZ A;  3KSE A;  2XU5 A;  4YYU A;  1ME4 A;  4FJC A;  3PW3 A;  4QBB A;  2GFO A;  3HD3 A;  4NV7 A;  2R9O A;  1Y4H A;  1F2A A;  2P7U A;  3WXF A;  1EF7 A;  3CBJ A;  2DJG B;  4PAD A;  4BS6 A;  3BWK A;  3BPM A;  2DC9 A;  2CIO A;  4YYS A;  1NL6 A;  2XU4 A;  2HD5 A;  3MHS A;  2G8E A;  3I3T A;  4YYR A;  2AVW A;  1MDW A;  3C9E A;  2AUZ A;  2DJF B;  1QOL A;  4X6I A;  7PCK A;  4YYW A;  3H89 A;  2DCB A;  1EWO A;  4PI3 A;  1MIR A;  4HWY A;  2B1N A;  2B1M A;  1QDQ A;  2F7D A;  2P0R A;  4Q8G A;  1ATK A;  1X9Y A;  2PAD A;  4QRX A;  3OF8 A;  1JQP A;  3RVW A;  3TNX A;  2G7Y A;  1XKG A;  1BY8 A;  1F2C A;  3IOQ A;  3BOW A;  2AYN A;  3HHA A;  1BGO A;  1BP4 A;  3MHH A;  1PPD A;  2HXZ A;  3P5U A;  4BGF A;  2YJ8 A;  4OEL A;  3RVV A;  1AYW A;  1TLO A;  1ICF A;  3E1Z B;  2PRE A;  1AYU A;  1CVZ A;  1K3B B;  3KX1 A;  2PNS A;  4N8W A;  2FYE A;  5CVM A;  3PBH A;  1DF0 A;  3BCN A;  2YJB A;  1KFX L;  2AS8 A;  1CTE A;  4DMY A;  4Q8H A;  2OP3 A;  1MS6 A;  3OF9 A;  3H7D A;  4W5C A;  4YYV A;  2CB5 A;  3K24 A;  1U9V A;  4X6J A;  4BPV A;  1QMY A;  1SP4 B;  3AI8 A;  3IEJ A;  4BSQ A;  1CS8 A;  1ME3 A;  3S3R A;  1VSN A;  3CBK A;  3RVX A;  4CDE B;  5FPW A;  3USV A;  4GUZ A;  4MSX A;  1YK7 A;  1TL9 A;  3K9M A;  1CSB B;  1KXR A;  3CH3 X;  2ACT A;  1PBH A;  4QRG A;  1PPO A;  3M99 A;  3OVZ A;  4PP2 E;  3KW9 A;  9PAP A;  1PPP A;  1AU0 A;  3NHE A;  3U8E A;  2DCD A;  3KWB X;  3P5X A;  4AXL A;  2G6D A;  2OZ2 A;  2FTD A;  1YVB A;  3I06 A;  3O1G A;  3KFQ A;  3WXG A;  3MOR A;  4P6E A;  1S4V A;  2AYO A;  3BC3 A;  5PAD A;  4YVA A;  3N3G A;  3P5V A;  2G8J A;  1ITO A;  2P86 A;  2BDZ A;  4MZO A;  4G54 A;  1CV8 A;  1BQI A;  1GEC E;  3H6S A;  4W4U A;  3V6E A;  1ZIV A;  4ZUX U;  4XR7 A;  1CJL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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