2YJ8A

Cathepsin l with a nitrile inhibitor
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
220
structure length
219
Chain Sequence
b'APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTSDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords CATHEPSIN L1
publication title Halogen Bonding at the Active Sites of Human Cathepsin L and Mek1 Kinase: Efficient Interactions in Different Environments.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 71
structure length 219
sequence length 220
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2011-05-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2yj8A00
1THEA 2E01A 2NQIA 4BPVA 3DF0A 3WXGA 2CIOA 1EWMA 3KKUA 4MZOA 5K16A 1KHPA 1CJLA 2FRAA 2HHNA 1AYVA 3M99A 2OULA 3H8CA 1DEUA 1PCIA 1NL6A 2JQFR 2JQGR 3QJ3A 4X6IA 2DC6A 2NQDB 4CDCB 4CZWA 3H89A 2R9OA 3IMAA 4KLBA 1PPNA 5J94A 3WXEA 2DZYA 2IPPB 4CDEB 1U9VA 2PADA 1F2CA 3OF9A 4QRVA 2DCCA 2FTDA 3S3QA 1YALA 4PI3A 2YJCA 4QH6A 1NPZA 2GHUA 4FK5A 4YVAA 1STFE 1MHWA 4DMXA 3MHHA 1DF0A 1TLOA 3IUTA 4BSQA 1BP4A 4BS6A 5A24A 1EF7A 1U9XA 3RVWA 2NQGA 3IHPA 1X9YA 4I07A 3I3TA 1QXPA 2BDLA 2GFOA 2C0YA 4MZSA 4OEMA 2DC7A 1AU0A 2DC9A 3KW9A 3K9MA 1Y4HA 3KSEA 4CDDB 2PNSA 1JQPA 2O6XA 2FQ9A 4W4UA 4QBBA 4P6EA 1AU3A 1AYUA 2IBIA 1NQCA 2YJ9A 1CVZA 3OVXA 4Q8HA 3CBKA 3TNXA 1HUCB 2P0RA 1YT7A 1POPA 7PCKA 1QMYA 2FYEA 4YYQA 4N4ZA 3USVA 1YK8A 3N4CA 2AIMA 2FUDA 3RVXA 1U9QX 2DJFB 3K24A 2B1MA 3F5VA 3AI8A 1AIMA 2VHSA 3IV2A 2AS8A 1EWLA 1MDWA 4QRXA 3CH3X 5CHTA 4YYRA 1NLJA 2AYNA 5JH3A 2R9CA 5CVOB 5CVNB 1YVBA 2WBFX 2DC8A 4AXMA 1AU4A 3F75A 3PDFA 1PBHA 4N8WA 1AU2A 3I06A 2NQAA 1ZIVA 3HHAA 3E1ZB 1F2BA 3H8BA 4BQVA 5JA7A 1F2AA 2PBHA 2P86A 3KX1A 4G54A 1EWPA 3PNRA 1ZCMA 2OP3A 8PCHA 1ME4A 1PPDA 3MORA 1PPOA 3PBHA 1PE6A 1MIRA 4P6GA 3MTNA 1U5IA 2AVWA 2FO5A 1BGOA 2Y5BA 1U9WA 1ICFA 4XR7A 1PXVA 5EF4A 1CTEA 4DMYA 4X6JA 5FPWA 2VHFA 2G8JA 1PIPA 2B1NA 2Y6EA 3C9EA 4PP2E 1IWDA 1M6DA 4OELA 4HWYA 4Q8GA 2YJ8A 1NB3A 3O1GA 1CB5A 1BY8A 1CPJA 1EWOA 2HH5A 1KFXL 1O0EA 3P5XA 1KHQA 3V6CA 3V6EA 4FIPA 2R9MA 2R6NA 6PADA 3KWBX 3ERVA 4XUIA 3WXFA 1QOLA 4WA6A 3BPFA 2CB5A 2DCBA 5EGWA 2DCAA 2DZZA 1ITOA 3BWKA 5F02A 5PADA 1Y08A 3ZUAA 4YV8A 1GECE 3KFQA 4I05A 4K7CA 2F7DA 1CS8A 1A6RA 1SNKA 2G7YA 3BPMA 2AU1A 4YYVA 2AUZA 3HHIA 4MSXA 3PW3A 4W5BA 2ARYA 1YK7A 3P5VA 2HD5A 1SP4B 3N3KA 2DJGB 3U8EA 2E00A 3BC3A 2OZ2A 3P5WA 5CHVA 3H6SA 3S3RA 1AECA 2H7JA 1MEMA 2F1GA 3KWZA 1MEGA 4YYSA 4YYWA 3OVZA 3QSDA 2FT2A 5CVMA 2BDZA 3LFYA 3O0UA 3D6SA 2AYOA 4FJCA 1GMYA 3CH2X 4PADA 3IEJA 2FRQA 3HD3A 2R9NA 4AXLA 3BCNA 3BOWA 4QRGA 1KXRA 3QT4A 2G6DA 1ME3A 1F29A 3B79A 2P7UA 1BQIA 2YJ2A 1FH0A 1KFUL 1TL9A 1VJVA 1GLOA 1PPPA 2HXZA 4YYUA 3N3GA 1XKGA 1S4VA 1Q6KA 4BS5A 3NHEA 2ATOA 3HWNA 2ACTA 4N79A 1QDQA 3RVVA 3LXSA 1ATKA 2G8EA 3OISA 3IOQA 1PADA 3GCBA 4I04A 2XU1A 4ZUXU 1GCBA 1CSBB 4W5CA 3P5UA 2E03A 4CDFB 2DCDA 1K3BB 1CQDA 2R9FA 1VSNA 3H7DA 1MS6A 1NB5A 3CBJA 1CV8A 4PP1A 2AUXA 9PAPA 2XU4A 3MHSA 2YJBA 2E02A 4X6HA 1AYWA 4RY2A 1TU6A 2XU5A 3K8UA 2PREA 2XU3A 3OF8A
chains in the Genus database with same CATH superfamily
1THEA 2E01A 2NQIA 4BPVA 4PT5A 3DF0A 3WXGA 4GUAA 2CIOA 1EWMA 3KKUA 4MZOA 5K16A 1KHPA 1CJLA 2FRAA 2HHNA 1AYVA 3M99A 2OULA 3H8CA 1DEUA 1PCIA 1NL6A 2JQFR 2JQGR 3QJ3A 4X6IA 2DC6A 2NQDB 4CDCB 4CZWA 3H89A 4XZXA 2R9OA 3IMAA 2BTWB 4BOPA 4KLBA 4BOSA 1PPNA 5J94A 3WXEA 2DZYA 2IPPB 4CDEB 1UKFA 1U9VA 2PADA 1F2CA 3OF9A 4QRVA 3W31A 2DCCA 2FTDA 3S3QA 1YALA 4PI3A 3E9SA 2YJCA 4QH6A 1NPZA 2GHUA 4FK5A 4YVAA 1STFE 1MHWA 4DMXA 3MHHA 1DF0A 1TLOA 3IUTA 4BSQA 3RNVA 1BP4A 4BS6A 5A24A 1EF7A 1U9XA 3RVWA 2NQGA 4MI7A 3IHPA 1X9YA 4I07A 3TMPA 3I3TA 1QXPA 2BDLA 2GFOA 2C0YA 3IFUA 4MZSA 4OEMA 2DC7A 1AU0A 2DC9A 3KW9A 3K9MA 1Y4HA 3C0RA 3KSEA 4CDDB 3W30A 2PNSA 2Z84A 1JQPA 4R3DA 2O6XA 2FQ9A 3PHWA 4QBBA 3MTVA 4P6EA 4W4UA 1AU3A 1AYUA 2IBIA 1NQCA 2YJ9A 4IP3A 1CVZA 3OVXA 4Q8HA 3B21A 4M0WA 3CBKA 3TNXA 4ZTBA 1HUCB 2P0RA 1YT7A 1POPA 7PCKA 1QMYA 2FYEA 4YYQA 4N4ZA 3USVA 3BY4A 1YK8A 3N4CA 2AIMA 2FUDA 3RVXA 1U9QX 2DJFB 3K24A 2B1MA 3F5VA 3AI8A 1AIMA 3TRKA 2VHSA 3IV2A 2AS8A 3MP2A 1EWLA 1MDWA 4QRXA 4A5UA 3CH3X 5CHTA 2J7QA 4YYRA 1NLJA 2AYNA 5JH3A 2R9CA 5CVOB 5CVNB 1YVBA 2WBFX 2DC8A 4AXMA 1AU4A 3F75A 3PDFA 1PBHA 3OQCA 4N8WA 2UZJA 1AU2A 3I06A 2NQAA 1ZIVA 1YZBA 3HHAA 3E1ZB 1F2BA 3H8BA 4BQVA 5JA7A 1F2AA 2PBHA 2P86A 3KX1A 4G54A 1EWPA 3PNRA 4BOZA 1ZCMA 4OVZA 4RF1A 2J7QC 2OP3A 8PCHA 1ME4A 1PPDA 3MORA 1PPOA 3PBHA 1PE6A 1MIRA 4P6GA 3MTNA 3PHXA 1U5IA 2AVWA 2FO5A 1BGOA 2Y5BA 1U9WA 1ICFA 4XR7A 1PXVA 5EF4A 1CTEA 4DMYA 3PRPA 4X6JA 5FPWA 2VHFA 2G8JA 1PIPA 2B1NA 2Y6EA 3C9EA 4D8EA 4PP2E 1IWDA 1M6DA 4BOQA 4OELA 4HWYA 4Q8GA 2YJ8A 1NB3A 3O1GA 1CB5A 1BY8A 1CPJA 1EWOA 2FE8A 2HH5A 1KFXL 1O0EA 3P5XA 1KHQA 3PHUA 3V6CA 4FIPA 4OW0A 3V6EA 2R9MA 2JTCA 2R6NA 3PT2A 6PADA 3KWBX 3ERVA 4XUIA 4D8IA 3WXFA 1QOLA 4WA6A 3BPFA 2CB5A 2DCBA 5EGWA 2DCAA 2DZZA 1ITOA 3BWKA 5F02A 5PADA 1DKIA 1Y08A 3ZUAA 4YV8A 1GECE 3KFQA 4I05A 4K7CA 2F7DA 1CS8A 1A6RA 3ZNHA 1SNKA 2G7YA 4RKXA 2JRIA 3BPMA 2AU1A 4YYVA 2AUZA 3HHIA 4MSXA 3PW3A 1PVJA 4W5BA 2ARYA 1YK7A 3P5VA 2HD5A 1SP4B 3N3KA 3BB7A 2DJGB 3U8EA 2E00A 3BC3A 2OZ2A 2HWKA 2BU3A 3P5WA 5CHVA 3H6SA 4HXDB 3S3RA 1AECA 2H7JA 1MEMA 2F1GA 3KWZA 5EZSA 1MEGA 4BOUA 4YYSA 4YYWA 3OVZA 3QSDA 5JZEA 2FT2A 5CVMA 2BDZA 3LFYA 3O0UA 3D6SA 3PRMA 2AYOA 4FJCA 1GMYA 3CH2X 4REZA 4PADA 3IEJA 2FRQA 3HD3A 2R9NA 3PSEA 4AXLA 3BCNA 2AGAA 3BOWA 4QRGA 1KXRA 3QT4A 2G6DA 4P16A 1ME3A 1F29A 3B79A 2P7UA 1BQIA 2YJ2A 1FH0A 1KFUL 1TL9A 1VJVA 1GLOA 1PPPA 2HXZA 4YYUA 3N3GA 1XKGA 1S4VA 3MJ5A 3O65A 1Q6KA 4BS5A 3NHEA 2ATOA 3HWNA 2ACTA 4N79A 5EZQA 1QDQA 3RVVA 3LXSA 1ATKA 3BBAA 4IUMA 2G8EA 3OISA 4OVZB 2DOSA 3IOQA 1PADA 3GCBA 4I04A 5E6JA 2XU1A 4RF0A 4ZUXU 4WURA 1GCBA 1CSBB 4W5CA 3P5UA 2E03A 4CDFB 2DCDA 5KO3A 4RNAA 1K3BB 1CQDA 4D8BA 2R9FA 1VSNA 3H7DA 1MS6A 1NB5A 3CBJA 1CV8A 4PP1A 2AUXA 9PAPA 2XU4A 4MM3B 3MHSA 2YJBA 2E02A 4X6HA 1AYWA 4RY2A 1TU6A 2XU5A 3K8UA 2PREA 2BTWA 2XU3A 3OF8A
chains in the Genus database with same CATH topology
1THEA 2E01A 2NQIA 4BPVA 3DF0A 3WXGA 2CIOA 1EWMA 3KKUA 4MZOA 5K16A 1KHPA 1CJLA 2FRAA 2HHNA 1AYVA 3M99A 2OULA 3H8CA 1DEUA 1PCIA 1NL6A 2JQFR 2JQGR 3QJ3A 4X6IA 2DC6A 2NQDB 4CDCB 4CZWA 3H89A 2R9OA 3IMAA 4KLBA 1PPNA 5J94A 3WXEA 2DZYA 2IPPB 4CDEB 1U9VA 2PADA 1F2CA 3OF9A 4QRVA 2DCCA 2FTDA 3S3QA 1YALA 4PI3A 2YJCA 4QH6A 1NPZA 2GHUA 4FK5A 4YVAA 1STFE 1MHWA 4DMXA 3MHHA 1DF0A 1TLOA 3IUTA 4BSQA 1BP4A 4BS6A 5A24A 1EF7A 1U9XA 3RVWA 2NQGA 1W5RA 3IHPA 1X9YA 4I07A 3I3TA 1GX3A 1QXPA 2BDLA 2BSZA 2GFOA 2C0YA 4MZSA 4OEMA 2DC7A 1AU0A 2DC9A 3KW9A 3K9MA 1Y4HA 3KSEA 1E2TA 4CDDB 2PNSA 1JQPA 2O6XA 2FQ9A 4W4UA 4QBBA 4P6EA 1AU3A 1AYUA 2IBIA 1NQCA 2YJ9A 1CVZA 3OVXA 4Q8HA 3CBKA 3TNXA 1HUCB 2P0RA 1YT7A 1POPA 4GUZA 7PCKA 1QMYA 2FYEA 4YYQA 4N4ZA 3USVA 1YK8A 3N4CA 2AIMA 2FUDA 3RVXA 1U9QX 2DJFB 3K24A 2B1MA 4B55A 3F5VA 3AI8A 1AIMA 2VHSA 3IV2A 2AS8A 1EWLA 1MDWA 4QRXA 3CH3X 3D9WA 5CHTA 4YYRA 1NLJA 2AYNA 5JH3A 2R9CA 5CVOB 5CVNB 1YVBA 2WBFX 2DC8A 4AXMA 1AU4A 3F75A 3PDFA 2VFBA 1PBHA 4N8WA 1AU2A 3I06A 2NQAA 1ZIVA 3HHAA 3E1ZB 1F2BA 3H8BA 4NV7A 4BQVA 5JA7A 1F2AA 2PBHA 2P86A 3KX1A 4G54A 1EWPA 3PNRA 1ZCMA 2OP3A 8PCHA 1ME4A 1PPDA 3MORA 1PPOA 3PBHA 1PE6A 1MIRA 4P6GA 3MTNA 1U5IA 2AVWA 2FO5A 1BGOA 2Y5BA 1U9WA 1ICFA 4XR7A 1PXVA 5EF4A 1CTEA 4DMYA 4X6JA 5FPWA 2VHFA 2G8JA 1PIPA 2B1NA 2Y6EA 3C9EA 4PP2E 1IWDA 1M6DA 4OELA 4HWYA 4Q8GA 2YJ8A 1NB3A 3O1GA 1CB5A 1BY8A 1CPJA 1EWOA 2HH5A 1KFXL 1O0EA 3P5XA 1KHQA 3V6CA 3V6EA 4FIPA 2R9MA 2R6NA 6PADA 3KWBX 3ERVA 4XUIA 3WXFA 1QOLA 1W4TA 4WA6A 3BPFA 2CB5A 2DCBA 5EGWA 2DCAA 2DZZA 1ITOA 3BWKA 5F02A 5PADA 1Y08A 3ZUAA 4YV8A 1GECE 3KFQA 4I05A 4K7CA 2F7DA 1CS8A 1A6RA 1SNKA 2G7YA 3BPMA 2AU1A 4YYVA 2AUZA 3HHIA 4MSXA 3PW3A 4W5BA 2ARYA 1YK7A 3P5VA 2HD5A 1SP4B 3N3KA 2DJGB 3U8EA 2E00A 3BC3A 2OZ2A 3P5WA 5CHVA 3H6SA 3S3RA 1AECA 2H7JA 1MEMA 2F1GA 3KWZA 3LTWA 1MEGA 4YYSA 4YYWA 3OVZA 3QSDA 2FT2A 5CVMA 2BDZA 3LFYA 4C5PA 3O0UA 3D6SA 2AYOA 4FJCA 1GMYA 3CH2X 4PADA 3IEJA 2FRQA 3HD3A 4BGFA 2R9NA 4AXLA 3BCNA 3BOWA 4QRGA 1KXRA 3QT4A 2G6DA 1ME3A 1F29A 3B79A 2P7UA 1BQIA 2YJ2A 1FH0A 1KFUL 1TL9A 1VJVA 1GLOA 1PPPA 2HXZA 4YYUA 3N3GA 1XKGA 1S4VA 1Q6KA 4BS5A 3NHEA 2ATOA 3HWNA 2ACTA 4N79A 1QDQA 3RVVA 3LXSA 1ATKA 2G8EA 3OISA 3IOQA 1PADA 3GCBA 4I04A 2XU1A 4ZUXU 1GCBA 1CSBB 4W5CA 3P5UA 2E03A 4CDFB 2DCDA 1K3BB 1CQDA 2R9FA 1VSNA 3H7DA 1MS6A 4NV8A 1NB5A 3CBJA 1CV8A 2VFCA 4PP1A 2AUXA 9PAPA 2XU4A 3MHSA 1W6FA 2YJBA 2E02A 4X6HA 1AYWA 4RY2A 1TU6A 2XU5A 3K8UA 2PREA 2XU3A 3OF8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1THE A;  2E01 A;  2NQI A;  4BPV A;  3DF0 A;  3WXG A;  2CIO A;  1EWM A;  3KKU A;  4MZO A;  5K16 A;  1KHP A;  1CJL A;  2FRA A;  2HHN A;  1AYV A;  3M99 A;  2OUL A;  3H8C A;  1DEU A;  1PCI A;  1NL6 A;  2JQF R;  2JQG R;  3QJ3 A;  4X6I A;  2DC6 A;  2NQD B;  4CDC B;  4CZW A;  3H89 A;  2R9O A;  3IMA A;  4KLB A;  1PPN A;  5J94 A;  3WXE A;  2DZY A;  2IPP B;  4CDE B;  1U9V A;  2PAD A;  1F2C A;  3OF9 A;  4QRV A;  2DCC A;  2FTD A;  3S3Q A;  1YAL A;  4PI3 A;  2YJC A;  4QH6 A;  1NPZ A;  2GHU A;  4FK5 A;  4YVA A;  1STF E;  1MHW A;  4DMX A;  3MHH A;  1DF0 A;  1TLO A;  3IUT A;  4BSQ A;  1BP4 A;  4BS6 A;  5A24 A;  1EF7 A;  1U9X A;  3RVW A;  2NQG A;  3IHP A;  1X9Y A;  4I07 A;  3I3T A;  1QXP A;  2BDL A;  2GFO A;  2C0Y A;  4MZS A;  4OEM A;  2DC7 A;  1AU0 A;  2DC9 A;  3KW9 A;  3K9M A;  1Y4H A;  3KSE A;  4CDD B;  2PNS A;  1JQP A;  2O6X A;  2FQ9 A;  4W4U A;  4QBB A;  4P6E A;  1AU3 A;  1AYU A;  2IBI A;  1NQC A;  2YJ9 A;  1CVZ A;  3OVX A;  4Q8H A;  3CBK A;  3TNX A;  1HUC B;  2P0R A;  1YT7 A;  1POP A;  7PCK A;  1QMY A;  2FYE A;  4YYQ A;  4N4Z A;  3USV A;  1YK8 A;  3N4C A;  2AIM A;  2FUD A;  3RVX A;  1U9Q X;  2DJF B;  3K24 A;  2B1M A;  3F5V A;  3AI8 A;  1AIM A;  2VHS A;  3IV2 A;  2AS8 A;  1EWL A;  1MDW A;  4QRX A;  3CH3 X;  5CHT A;  4YYR A;  1NLJ A;  2AYN A;  5JH3 A;  2R9C A;  5CVO B;  5CVN B;  1YVB A;  2WBF X;  2DC8 A;  4AXM A;  1AU4 A;  3F75 A;  3PDF A;  1PBH A;  4N8W A;  1AU2 A;  3I06 A;  2NQA A;  1ZIV A;  3HHA A;  3E1Z B;  1F2B A;  3H8B A;  4BQV A;  5JA7 A;  1F2A A;  2PBH A;  2P86 A;  3KX1 A;  4G54 A;  1EWP A;  3PNR A;  1ZCM A;  2OP3 A;  8PCH A;  1ME4 A;  1PPD A;  3MOR A;  1PPO A;  3PBH A;  1PE6 A;  1MIR A;  4P6G A;  3MTN A;  1U5I A;  2AVW A;  2FO5 A;  1BGO A;  2Y5B A;  1U9W A;  1ICF A;  4XR7 A;  1PXV A;  5EF4 A;  1CTE A;  4DMY A;  4X6J A;  5FPW A;  2VHF A;  2G8J A;  1PIP A;  2B1N A;  2Y6E A;  3C9E A;  4PP2 E;  1IWD A;  1M6D A;  4OEL A;  4HWY A;  4Q8G A;  2YJ8 A;  1NB3 A;  3O1G A;  1CB5 A;  1BY8 A;  1CPJ A;  1EWO A;  2HH5 A;  1KFX L;  1O0E A;  3P5X A;  1KHQ A;  3V6C A;  3V6E A;  4FIP A;  2R9M A;  2R6N A;  6PAD A;  3KWB X;  3ERV A;  4XUI A;  3WXF A;  1QOL A;  4WA6 A;  3BPF A;  2CB5 A;  2DCB A;  5EGW A;  2DCA A;  2DZZ A;  1ITO A;  3BWK A;  5F02 A;  5PAD A;  1Y08 A;  3ZUA A;  4YV8 A;  1GEC E;  3KFQ A;  4I05 A;  4K7C A;  2F7D A;  1CS8 A;  1A6R A;  1SNK A;  2G7Y A;  3BPM A;  2AU1 A;  4YYV A;  2AUZ A;  3HHI A;  4MSX A;  3PW3 A;  4W5B A;  2ARY A;  1YK7 A;  3P5V A;  2HD5 A;  1SP4 B;  3N3K A;  2DJG B;  3U8E A;  2E00 A;  3BC3 A;  2OZ2 A;  3P5W A;  5CHV A;  3H6S A;  3S3R A;  1AEC A;  2H7J A;  1MEM A;  2F1G A;  3KWZ A;  1MEG A;  4YYS A;  4YYW A;  3OVZ A;  3QSD A;  2FT2 A;  5CVM A;  2BDZ A;  3LFY A;  3O0U A;  3D6S A;  2AYO A;  4FJC A;  1GMY A;  3CH2 X;  4PAD A;  3IEJ A;  2FRQ A;  3HD3 A;  2R9N A;  4AXL A;  3BCN A;  3BOW A;  4QRG A;  1KXR A;  3QT4 A;  2G6D A;  1ME3 A;  1F29 A;  3B79 A;  2P7U A;  1BQI A;  2YJ2 A;  1FH0 A;  1KFU L;  1TL9 A;  1VJV A;  1GLO A;  1PPP A;  2HXZ A;  4YYU A;  3N3G A;  1XKG A;  1S4V A;  1Q6K A;  4BS5 A;  3NHE A;  2ATO A;  3HWN A;  2ACT A;  4N79 A;  1QDQ A;  3RVV A;  3LXS A;  1ATK A;  2G8E A;  3OIS A;  3IOQ A;  1PAD A;  3GCB A;  4I04 A;  2XU1 A;  4ZUX U;  1GCB A;  1CSB B;  4W5C A;  3P5U A;  2E03 A;  4CDF B;  2DCD A;  1K3B B;  1CQD A;  2R9F A;  1VSN A;  3H7D A;  1MS6 A;  1NB5 A;  3CBJ A;  1CV8 A;  4PP1 A;  2AUX A;  9PAP A;  2XU4 A;  3MHS A;  2YJB A;  2E02 A;  4X6H A;  1AYW A;  4RY2 A;  1TU6 A;  2XU5 A;  3K8U A;  2PRE A;  2XU3 A;  3OF8 A; 
#chains in the Genus database with same CATH topology
 1THE A;  2E01 A;  2NQI A;  4BPV A;  4PT5 A;  3DF0 A;  3WXG A;  4GUA A;  2CIO A;  1EWM A;  3KKU A;  4MZO A;  5K16 A;  1KHP A;  1CJL A;  2FRA A;  2HHN A;  1AYV A;  3M99 A;  2OUL A;  3H8C A;  1DEU A;  1PCI A;  1NL6 A;  2JQF R;  2JQG R;  3QJ3 A;  4X6I A;  2DC6 A;  2NQD B;  4CDC B;  4CZW A;  3H89 A;  4XZX A;  2R9O A;  3IMA A;  2BTW B;  4BOP A;  4KLB A;  4BOS A;  1PPN A;  5J94 A;  3WXE A;  2DZY A;  2IPP B;  4CDE B;  1UKF A;  1U9V A;  2PAD A;  1F2C A;  3OF9 A;  4QRV A;  3W31 A;  2DCC A;  2FTD A;  3S3Q A;  1YAL A;  4PI3 A;  3E9S A;  2YJC A;  4QH6 A;  1NPZ A;  2GHU A;  4FK5 A;  4YVA A;  1STF E;  1MHW A;  4DMX A;  3MHH A;  1DF0 A;  1TLO A;  3IUT A;  4BSQ A;  3RNV A;  1BP4 A;  4BS6 A;  5A24 A;  1EF7 A;  1U9X A;  3RVW A;  2NQG A;  4MI7 A;  3IHP A;  1X9Y A;  4I07 A;  3TMP A;  3I3T A;  1QXP A;  2BDL A;  2GFO A;  2C0Y A;  3IFU A;  4MZS A;  4OEM A;  2DC7 A;  1AU0 A;  2DC9 A;  3KW9 A;  3K9M A;  1Y4H A;  3C0R A;  3KSE A;  4CDD B;  3W30 A;  2PNS A;  2Z84 A;  1JQP A;  4R3D A;  2O6X A;  2FQ9 A;  3PHW A;  4QBB A;  3MTV A;  4P6E A;  4W4U A;  1AU3 A;  1AYU A;  2IBI A;  1NQC A;  2YJ9 A;  4IP3 A;  1CVZ A;  3OVX A;  4Q8H A;  3B21 A;  4M0W A;  3CBK A;  3TNX A;  4ZTB A;  1HUC B;  2P0R A;  1YT7 A;  1POP A;  7PCK A;  1QMY A;  2FYE A;  4YYQ A;  4N4Z A;  3USV A;  3BY4 A;  1YK8 A;  3N4C A;  2AIM A;  2FUD A;  3RVX A;  1U9Q X;  2DJF B;  3K24 A;  2B1M A;  3F5V A;  3AI8 A;  1AIM A;  3TRK A;  2VHS A;  3IV2 A;  2AS8 A;  3MP2 A;  1EWL A;  1MDW A;  4QRX A;  4A5U A;  3CH3 X;  5CHT A;  2J7Q A;  4YYR A;  1NLJ A;  2AYN A;  5JH3 A;  2R9C A;  5CVO B;  5CVN B;  1YVB A;  2WBF X;  2DC8 A;  4AXM A;  1AU4 A;  3F75 A;  3PDF A;  1PBH A;  3OQC A;  4N8W A;  2UZJ A;  1AU2 A;  3I06 A;  2NQA A;  1ZIV A;  1YZB A;  3HHA A;  3E1Z B;  1F2B A;  3H8B A;  4BQV A;  5JA7 A;  1F2A A;  2PBH A;  2P86 A;  3KX1 A;  4G54 A;  1EWP A;  3PNR A;  4BOZ A;  1ZCM A;  4OVZ A;  4RF1 A;  2J7Q C;  2OP3 A;  8PCH A;  1ME4 A;  1PPD A;  3MOR A;  1PPO A;  3PBH A;  1PE6 A;  1MIR A;  4P6G A;  3MTN A;  3PHX A;  1U5I A;  2AVW A;  2FO5 A;  1BGO A;  2Y5B A;  1U9W A;  1ICF A;  4XR7 A;  1PXV A;  5EF4 A;  1CTE A;  4DMY A;  3PRP A;  4X6J A;  5FPW A;  2VHF A;  2G8J A;  1PIP A;  2B1N A;  2Y6E A;  3C9E A;  4D8E A;  4PP2 E;  1IWD A;  1M6D A;  4BOQ A;  4OEL A;  4HWY A;  4Q8G A;  2YJ8 A;  1NB3 A;  3O1G A;  1CB5 A;  1BY8 A;  1CPJ A;  1EWO A;  2FE8 A;  2HH5 A;  1KFX L;  1O0E A;  3P5X A;  1KHQ A;  3PHU A;  3V6C A;  4FIP A;  4OW0 A;  3V6E A;  2R9M A;  2JTC A;  2R6N A;  3PT2 A;  6PAD A;  3KWB X;  3ERV A;  4XUI A;  4D8I A;  3WXF A;  1QOL A;  4WA6 A;  3BPF A;  2CB5 A;  2DCB A;  5EGW A;  2DCA A;  2DZZ A;  1ITO A;  3BWK A;  5F02 A;  5PAD A;  1DKI A;  1Y08 A;  3ZUA A;  4YV8 A;  1GEC E;  3KFQ A;  4I05 A;  4K7C A;  2F7D A;  1CS8 A;  1A6R A;  3ZNH A;  1SNK A;  2G7Y A;  4RKX A;  2JRI A;  3BPM A;  2AU1 A;  4YYV A;  2AUZ A;  3HHI A;  4MSX A;  3PW3 A;  1PVJ A;  4W5B A;  2ARY A;  1YK7 A;  3P5V A;  2HD5 A;  1SP4 B;  3N3K A;  3BB7 A;  2DJG B;  3U8E A;  2E00 A;  3BC3 A;  2OZ2 A;  2HWK A;  2BU3 A;  3P5W A;  5CHV A;  3H6S A;  4HXD B;  3S3R A;  1AEC A;  2H7J A;  1MEM A;  2F1G A;  3KWZ A;  5EZS A;  1MEG A;  4BOU A;  4YYS A;  4YYW A;  3OVZ A;  3QSD A;  5JZE A;  2FT2 A;  5CVM A;  2BDZ A;  3LFY A;  3O0U A;  3D6S A;  3PRM A;  2AYO A;  4FJC A;  1GMY A;  3CH2 X;  4REZ A;  4PAD A;  3IEJ A;  2FRQ A;  3HD3 A;  2R9N A;  3PSE A;  4AXL A;  3BCN A;  2AGA A;  3BOW A;  4QRG A;  1KXR A;  3QT4 A;  2G6D A;  4P16 A;  1ME3 A;  1F29 A;  3B79 A;  2P7U A;  1BQI A;  2YJ2 A;  1FH0 A;  1KFU L;  1TL9 A;  1VJV A;  1GLO A;  1PPP A;  2HXZ A;  4YYU A;  3N3G A;  1XKG A;  1S4V A;  3MJ5 A;  3O65 A;  1Q6K A;  4BS5 A;  3NHE A;  2ATO A;  3HWN A;  2ACT A;  4N79 A;  5EZQ A;  1QDQ A;  3RVV A;  3LXS A;  1ATK A;  3BBA A;  4IUM A;  2G8E A;  3OIS A;  4OVZ B;  2DOS A;  3IOQ A;  1PAD A;  3GCB A;  4I04 A;  5E6J A;  2XU1 A;  4RF0 A;  4ZUX U;  4WUR A;  1GCB A;  1CSB B;  4W5C A;  3P5U A;  2E03 A;  4CDF B;  2DCD A;  5KO3 A;  4RNA A;  1K3B B;  1CQD A;  4D8B A;  2R9F A;  1VSN A;  3H7D A;  1MS6 A;  1NB5 A;  3CBJ A;  1CV8 A;  4PP1 A;  2AUX A;  9PAP A;  2XU4 A;  4MM3 B;  3MHS A;  2YJB A;  2E02 A;  4X6H A;  1AYW A;  4RY2 A;  1TU6 A;  2XU5 A;  3K8U A;  2PRE A;  2BTW A;  2XU3 A;  3OF8 A; 
#chains in the Genus database with same CATH homology
 1THE A;  2E01 A;  2NQI A;  4BPV A;  3DF0 A;  3WXG A;  2CIO A;  1EWM A;  3KKU A;  4MZO A;  5K16 A;  1KHP A;  1CJL A;  2FRA A;  2HHN A;  1AYV A;  3M99 A;  2OUL A;  3H8C A;  1DEU A;  1PCI A;  1NL6 A;  2JQF R;  2JQG R;  3QJ3 A;  4X6I A;  2DC6 A;  2NQD B;  4CDC B;  4CZW A;  3H89 A;  2R9O A;  3IMA A;  4KLB A;  1PPN A;  5J94 A;  3WXE A;  2DZY A;  2IPP B;  4CDE B;  1U9V A;  2PAD A;  1F2C A;  3OF9 A;  4QRV A;  2DCC A;  2FTD A;  3S3Q A;  1YAL A;  4PI3 A;  2YJC A;  4QH6 A;  1NPZ A;  2GHU A;  4FK5 A;  4YVA A;  1STF E;  1MHW A;  4DMX A;  3MHH A;  1DF0 A;  1TLO A;  3IUT A;  4BSQ A;  1BP4 A;  4BS6 A;  5A24 A;  1EF7 A;  1U9X A;  3RVW A;  2NQG A;  1W5R A;  3IHP A;  1X9Y A;  4I07 A;  3I3T A;  1GX3 A;  1QXP A;  2BDL A;  2BSZ A;  2GFO A;  2C0Y A;  4MZS A;  4OEM A;  2DC7 A;  1AU0 A;  2DC9 A;  3KW9 A;  3K9M A;  1Y4H A;  3KSE A;  1E2T A;  4CDD B;  2PNS A;  1JQP A;  2O6X A;  2FQ9 A;  4W4U A;  4QBB A;  4P6E A;  1AU3 A;  1AYU A;  2IBI A;  1NQC A;  2YJ9 A;  1CVZ A;  3OVX A;  4Q8H A;  3CBK A;  3TNX A;  1HUC B;  2P0R A;  1YT7 A;  1POP A;  4GUZ A;  7PCK A;  1QMY A;  2FYE A;  4YYQ A;  4N4Z A;  3USV A;  1YK8 A;  3N4C A;  2AIM A;  2FUD A;  3RVX A;  1U9Q X;  2DJF B;  3K24 A;  2B1M A;  4B55 A;  3F5V A;  3AI8 A;  1AIM A;  2VHS A;  3IV2 A;  2AS8 A;  1EWL A;  1MDW A;  4QRX A;  3CH3 X;  3D9W A;  5CHT A;  4YYR A;  1NLJ A;  2AYN A;  5JH3 A;  2R9C A;  5CVO B;  5CVN B;  1YVB A;  2WBF X;  2DC8 A;  4AXM A;  1AU4 A;  3F75 A;  3PDF A;  2VFB A;  1PBH A;  4N8W A;  1AU2 A;  3I06 A;  2NQA A;  1ZIV A;  3HHA A;  3E1Z B;  1F2B A;  3H8B A;  4NV7 A;  4BQV A;  5JA7 A;  1F2A A;  2PBH A;  2P86 A;  3KX1 A;  4G54 A;  1EWP A;  3PNR A;  1ZCM A;  2OP3 A;  8PCH A;  1ME4 A;  1PPD A;  3MOR A;  1PPO A;  3PBH A;  1PE6 A;  1MIR A;  4P6G A;  3MTN A;  1U5I A;  2AVW A;  2FO5 A;  1BGO A;  2Y5B A;  1U9W A;  1ICF A;  4XR7 A;  1PXV A;  5EF4 A;  1CTE A;  4DMY A;  4X6J A;  5FPW A;  2VHF A;  2G8J A;  1PIP A;  2B1N A;  2Y6E A;  3C9E A;  4PP2 E;  1IWD A;  1M6D A;  4OEL A;  4HWY A;  4Q8G A;  2YJ8 A;  1NB3 A;  3O1G A;  1CB5 A;  1BY8 A;  1CPJ A;  1EWO A;  2HH5 A;  1KFX L;  1O0E A;  3P5X A;  1KHQ A;  3V6C A;  3V6E A;  4FIP A;  2R9M A;  2R6N A;  6PAD A;  3KWB X;  3ERV A;  4XUI A;  3WXF A;  1QOL A;  1W4T A;  4WA6 A;  3BPF A;  2CB5 A;  2DCB A;  5EGW A;  2DCA A;  2DZZ A;  1ITO A;  3BWK A;  5F02 A;  5PAD A;  1Y08 A;  3ZUA A;  4YV8 A;  1GEC E;  3KFQ A;  4I05 A;  4K7C A;  2F7D A;  1CS8 A;  1A6R A;  1SNK A;  2G7Y A;  3BPM A;  2AU1 A;  4YYV A;  2AUZ A;  3HHI A;  4MSX A;  3PW3 A;  4W5B A;  2ARY A;  1YK7 A;  3P5V A;  2HD5 A;  1SP4 B;  3N3K A;  2DJG B;  3U8E A;  2E00 A;  3BC3 A;  2OZ2 A;  3P5W A;  5CHV A;  3H6S A;  3S3R A;  1AEC A;  2H7J A;  1MEM A;  2F1G A;  3KWZ A;  3LTW A;  1MEG A;  4YYS A;  4YYW A;  3OVZ A;  3QSD A;  2FT2 A;  5CVM A;  2BDZ A;  3LFY A;  4C5P A;  3O0U A;  3D6S A;  2AYO A;  4FJC A;  1GMY A;  3CH2 X;  4PAD A;  3IEJ A;  2FRQ A;  3HD3 A;  4BGF A;  2R9N A;  4AXL A;  3BCN A;  3BOW A;  4QRG A;  1KXR A;  3QT4 A;  2G6D A;  1ME3 A;  1F29 A;  3B79 A;  2P7U A;  1BQI A;  2YJ2 A;  1FH0 A;  1KFU L;  1TL9 A;  1VJV A;  1GLO A;  1PPP A;  2HXZ A;  4YYU A;  3N3G A;  1XKG A;  1S4V A;  1Q6K A;  4BS5 A;  3NHE A;  2ATO A;  3HWN A;  2ACT A;  4N79 A;  1QDQ A;  3RVV A;  3LXS A;  1ATK A;  2G8E A;  3OIS A;  3IOQ A;  1PAD A;  3GCB A;  4I04 A;  2XU1 A;  4ZUX U;  1GCB A;  1CSB B;  4W5C A;  3P5U A;  2E03 A;  4CDF B;  2DCD A;  1K3B B;  1CQD A;  2R9F A;  1VSN A;  3H7D A;  1MS6 A;  4NV8 A;  1NB5 A;  3CBJ A;  1CV8 A;  2VFC A;  4PP1 A;  2AUX A;  9PAP A;  2XU4 A;  3MHS A;  1W6F A;  2YJB A;  2E02 A;  4X6H A;  1AYW A;  4RY2 A;  1TU6 A;  2XU5 A;  3K8U A;  2PRE A;  2XU3 A;  3OF8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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