3PHWA

Otu domain of crimean congo hemorrhagic fever virus in complex with ubiquitin
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
160
structure length
156
Chain Sequence
FLRSLDWTQVIAGQYVSNPRFNISDYFEIVRQPGDGNCFYHSIAELTMPNKTDHSYHYIKRLTESAARKYYQEEPEARLVGLSLEDYLKRMLSDNEWGSTLEASMLAKEMGITIIIWTVEVEAGIKFGDGDVFTAVNLLHSGQTHFDALRILPQFE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains.
pubmed doi rcsb
molecule tags Hydrolase/ribosomal protein
source organism Crimean-congo hemorrhagic fever virus strain ibar10200
molecule keywords RNA-directed RNA polymerase L
total genus 48
structure length 156
sequence length 160
chains with identical sequence C, E, G
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 2010-11-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02338 OTU OTU-like cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.80 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cathepsin B; Chain A 3phwA00
4BOSA 4BOUA 4BOZA 3PHWA 5JZEA 4BOPA 3PRPA 3ZNHA 3PSEA 3PRMA 3C0RA 3PHUA 4BOQA 3BY4A 3PT2A 3TMPA 3PHXA 4HXDB
chains in the Genus database with same CATH superfamily
1AYVA 2WBFX 4MSXA 3LFYA 2R9MA 5CVOB 2AYNA 2FT2A 4MZSA 1NB5A 1QOLA 4OELA 3KWZA 3TNXA 2AU1A 1AU0A 2O6XA 4MZOA 4FK5A 3ZNHA 4DMYA 3O65A 3I06A 4BOZA 2JQGR 4PT5A 2JTCA 5EZSA 4CDFB 4R3DA 2ACTA 3MTNA 4I05A 2DCBA 2DCAA 3N3GA 3OF9A 3RNVA 1YK7A 1QXPA 4I07A 4RKXA 3PW3A 2R6NA 4CDDB 2P7UA 3ERVA 4Q8HA 4OVZB 1U5IA 4X6HA 2BTWA 3PT2A 4W5BA 2FYEA 1MEMA 1O0EA 1AIMA 2IPPB 3S3QA 3E9SA 1X9YA 3MTVA 1DF0A 5KO3A 1BP4A 1AU2A 1Y08A 1AECA 3H8BA 1EF7A 2DJGB 2AVWA 3PHUA 1PBHA 4X6JA 2BDLA 3CH2X 2VHFA 1GLOA 4IP3A 4QRGA 3CBJA 2IBIA 2Y5BA 3PNRA 5EF4A 2YJBA 5K16A 4N4ZA 4MM3B 1PXVA 3PBHA 1GECE 1PPNA 1AU3A 2OULA 5JA7A 4PADA 1SNKA 1NQCA 1NB3A 3KWBX 3PHXA 5EGWA 3WXEA 2E01A 2AIMA 4BOPA 4YYRA 2BU3A 3M99A 3AI8A 3MJ5A 1JQPA 4D8IA 1CB5A 4BS5A 2R9OA 1MEGA 1PADA 1TL9A 1DEUA 4QRXA 4OW0A 1THEA 2FQ9A 1F29A 1CQDA 3CBKA 2OP3A 1ICFA 1U9WA 1YT7A 3IV2A 3KSEA 1CTEA 3I3TA 1AU4A 1BY8A 1ZIVA 4BQVA 4GUAA 2BDZA 4RNAA 5CVNB 4OEMA 2AYOA 2F7DA 4W4UA 2VHSA 2DCDA 1PPOA 3F75A 4PP2E 2NQAA 3MHHA 3C0RA 2FO5A 2HD5A 3USVA 3F5VA 5E6JA 1NLJA 2DJFB 2FRQA 3KW9A 1DKIA 1CV8A 4A5UA 2GHUA 4WURA 4BSQA 3OISA 3WXGA 2AUXA 1ZCMA 2HXZA 3OVZA 4I04A 3ZUAA 4YYSA 4FIPA 2GFOA 1M6DA 1EWLA 1A6RA 3B79A 3PRMA 2XU5A 2FE8A 4G54A 4ZTBA 1MDWA 2DOSA 2XU4A 3K8UA 2AS8A 3V6EA 1UKFA 4M0WA 6PADA 3E1ZB 5F02A 1XKGA 2AGAA 3B21A 3OQCA 1VSNA 1U9XA 2OZ2A 2P0RA 3PDFA 3BY4A 3IFUA 1PVJA 3CH3X 1NL6A 1MS6A 2DZZA 2Z84A 4BOQA 4QBBA 3V6CA 3NHEA 2C0YA 2FTDA 3H7DA 3PRPA 1YVBA 2CIOA 2J7QC 1POPA 1TU6A 3N4CA 9PAPA 1ME3A 2YJCA 2J7QA 2XU3A 1MHWA 2E03A 3P5UA 3C9EA 4P6EA 1F2AA 3P5VA 2XU1A 2BTWB 4K7CA 1QDQA 3HD3A 3BOWA 3IOQA 4WA6A 5FPWA 2R9FA 4QRVA 2AUZA 4DMXA 1PCIA 1VJVA 4YYUA 1CJLA 1STFE 3QJ3A 1ITOA 1F2CA 1KHQA 5J94A 1Y4HA 2DC8A 2NQDB 4YYVA 3H8CA 4CZWA 3H89A 2FUDA 3WXFA 2PREA 4YV8A 4HXDB 3H6SA 3P5XA 2E02A 3RVWA 1KFUL 1CVZA 2CB5A 1YK8A 2DC9A 4BOSA 3IUTA 3O0UA 1TLOA 1PPPA 4YVAA 2B1NA 1U9VA 4RF1A 3TMPA 3LXSA 1PE6A 4W5CA 2F1GA 1EWMA 3KFQA 4XZXA 4CDCB 1BQIA 2G6DA 2YJ8A 2E00A 4CDEB 1EWOA 3MORA 1FH0A 1MIRA 3TRKA 4XUIA 2DC6A 4P16A 1HUCB 1BGOA 1AYUA 1ATKA 3HWNA 3HHAA 2R9CA 1IWDA 2UZJA 1SP4B 3W31A 4BS6A 2Y6EA 1AYWA 3O1GA 1KFXL 3OF8A 3OVXA 1EWPA 4YYWA 5JH3A 4N8WA 1QMYA 3BB7A 4RF0A 4REZA 2G8EA 2DC7A 2HHNA 4PI3A 3QSDA 7PCKA 1Q6KA 3BBAA 1NPZA 2YJ9A 3HHIA 4Q8GA 4N79A 2DZYA 1YZBA 4QH6A 4RY2A 2G8JA 2PNSA 1K3BB 1GMYA 3QT4A 3BPMA 3PHWA 4FJCA 2JQFR 3IHPA 2HWKA 5JZEA 8PCHA 3K9MA 4AXLA 1CPJA 2DCCA 2NQGA 1CS8A 2R9NA 2JRIA 3PSEA 5CVMA 2FRAA 3RVVA 1CSBB 2ATOA 3GCBA 3MHSA 4KLBA 3BCNA 3KKUA 4P6GA 3BWKA 3IMAA 4D8BA 5CHVA 3W30A 4AXMA 3U8EA 2YJ2A 3BPFA 4D8EA 3D6SA 4X6IA 3MP2A 4ZUXU 1YALA 2P86A 1U9QX 2NQIA 3BC3A 1S4VA 4HWYA 1KHPA 4PP1A 3KX1A 4BOUA 3N3KA 1KXRA 4IUMA 3K24A 2HH5A 3IEJA 5CHTA 2H7JA 5EZQA 3P5WA 1PPDA 2PBHA 4YYQA 2G7YA 4MI7A 4XR7A 5A24A 5PADA 2PADA 4BPVA 4OVZA 3RVXA 1F2BA 1PIPA 1ME4A 2B1MA 3S3RA 3DF0A 1GCBA 2ARYA
chains in the Genus database with same CATH topology
4OW0A 2BTWB 3BBAA 1YZBA 3ZNHA 4GUAA 3O65A 4RNAA 4BOZA 4PT5A 2JTCA 5EZSA 4R3DA 3PHWA 3RNVA 3C0RA 4RKXA 2HWKA 5JZEA 5E6JA 4OVZB 1DKIA 2BTWA 3PT2A 4A5UA 4WURA 2JRIA 3PSEA 4HXDB 3E9SA 3MTVA 4BOSA 5KO3A 4D8BA 3W30A 3PRMA 4RF1A 3TMPA 2FE8A 4D8EA 4ZTBA 3PHUA 2DOSA 3MP2A 4XZXA 1UKFA 4IP3A 4M0WA 2AGAA 3B21A 3OQCA 3TRKA 4MM3B 4P16A 4BOUA 3BY4A 3IFUA 1PVJA 4IUMA 5EZQA 2UZJA 3W31A 2Z84A 4BOQA 3PHXA 4MI7A 4BOPA 3PRPA 2BU3A 4OVZA 2J7QC 3BB7A 4RF0A 4REZA 3MJ5A 4D8IA 2J7QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BOS A;  4BOU A;  4BOZ A;  3PHW A;  5JZE A;  4BOP A;  3PRP A;  3ZNH A;  3PSE A;  3PRM A;  3C0R A;  3PHU A;  4BOQ A;  3BY4 A;  3PT2 A;  3TMP A;  3PHX A;  4HXD B; 
#chains in the Genus database with same CATH topology
 1AYV A;  2WBF X;  4MSX A;  3LFY A;  2R9M A;  5CVO B;  2AYN A;  2FT2 A;  4MZS A;  1NB5 A;  1QOL A;  4OEL A;  3KWZ A;  3TNX A;  2AU1 A;  1AU0 A;  2O6X A;  4MZO A;  4FK5 A;  3ZNH A;  4DMY A;  3O65 A;  3I06 A;  4BOZ A;  2JQG R;  4PT5 A;  2JTC A;  5EZS A;  4CDF B;  4R3D A;  2ACT A;  3MTN A;  4I05 A;  2DCB A;  2DCA A;  3N3G A;  3OF9 A;  3RNV A;  1YK7 A;  1QXP A;  4I07 A;  4RKX A;  3PW3 A;  2R6N A;  4CDD B;  2P7U A;  3ERV A;  4Q8H A;  4OVZ B;  1U5I A;  4X6H A;  2BTW A;  3PT2 A;  4W5B A;  2FYE A;  1MEM A;  1O0E A;  1AIM A;  2IPP B;  3S3Q A;  3E9S A;  1X9Y A;  3MTV A;  1DF0 A;  5KO3 A;  1BP4 A;  1AU2 A;  1Y08 A;  1AEC A;  3H8B A;  1EF7 A;  2DJG B;  2AVW A;  3PHU A;  1PBH A;  4X6J A;  2BDL A;  3CH2 X;  2VHF A;  1GLO A;  4IP3 A;  4QRG A;  3CBJ A;  2IBI A;  2Y5B A;  3PNR A;  5EF4 A;  2YJB A;  5K16 A;  4N4Z A;  4MM3 B;  1PXV A;  3PBH A;  1GEC E;  1PPN A;  1AU3 A;  2OUL A;  5JA7 A;  4PAD A;  1SNK A;  1NQC A;  1NB3 A;  3KWB X;  3PHX A;  5EGW A;  3WXE A;  2E01 A;  2AIM A;  4BOP A;  4YYR A;  2BU3 A;  3M99 A;  3AI8 A;  3MJ5 A;  1JQP A;  4D8I A;  1CB5 A;  4BS5 A;  2R9O A;  1MEG A;  1PAD A;  1TL9 A;  1DEU A;  4QRX A;  4OW0 A;  1THE A;  2FQ9 A;  1F29 A;  1CQD A;  3CBK A;  2OP3 A;  1ICF A;  1U9W A;  1YT7 A;  3IV2 A;  3KSE A;  1CTE A;  3I3T A;  1AU4 A;  1BY8 A;  1ZIV A;  4BQV A;  4GUA A;  2BDZ A;  4RNA A;  5CVN B;  4OEM A;  2AYO A;  2F7D A;  4W4U A;  2VHS A;  2DCD A;  1PPO A;  3F75 A;  4PP2 E;  2NQA A;  3MHH A;  3C0R A;  2FO5 A;  2HD5 A;  3USV A;  3F5V A;  5E6J A;  1NLJ A;  2DJF B;  2FRQ A;  3KW9 A;  1DKI A;  1CV8 A;  4A5U A;  2GHU A;  4WUR A;  4BSQ A;  3OIS A;  3WXG A;  2AUX A;  1ZCM A;  2HXZ A;  3OVZ A;  4I04 A;  3ZUA A;  4YYS A;  4FIP A;  2GFO A;  1M6D A;  1EWL A;  1A6R A;  3B79 A;  3PRM A;  2XU5 A;  2FE8 A;  4G54 A;  4ZTB A;  1MDW A;  2DOS A;  2XU4 A;  3K8U A;  2AS8 A;  3V6E A;  1UKF A;  4M0W A;  6PAD A;  3E1Z B;  5F02 A;  1XKG A;  2AGA A;  3B21 A;  3OQC A;  1VSN A;  1U9X A;  2OZ2 A;  2P0R A;  3PDF A;  3BY4 A;  3IFU A;  1PVJ A;  3CH3 X;  1NL6 A;  1MS6 A;  2DZZ A;  2Z84 A;  4BOQ A;  4QBB A;  3V6C A;  3NHE A;  2C0Y A;  2FTD A;  3H7D A;  3PRP A;  1YVB A;  2CIO A;  2J7Q C;  1POP A;  1TU6 A;  3N4C A;  9PAP A;  1ME3 A;  2YJC A;  2J7Q A;  2XU3 A;  1MHW A;  2E03 A;  3P5U A;  3C9E A;  4P6E A;  1F2A A;  3P5V A;  2XU1 A;  2BTW B;  4K7C A;  1QDQ A;  3HD3 A;  3BOW A;  3IOQ A;  4WA6 A;  5FPW A;  2R9F A;  4QRV A;  2AUZ A;  4DMX A;  1PCI A;  1VJV A;  4YYU A;  1CJL A;  1STF E;  3QJ3 A;  1ITO A;  1F2C A;  1KHQ A;  5J94 A;  1Y4H A;  2DC8 A;  2NQD B;  4YYV A;  3H8C A;  4CZW A;  3H89 A;  2FUD A;  3WXF A;  2PRE A;  4YV8 A;  4HXD B;  3H6S A;  3P5X A;  2E02 A;  3RVW A;  1KFU L;  1CVZ A;  2CB5 A;  1YK8 A;  2DC9 A;  4BOS A;  3IUT A;  3O0U A;  1TLO A;  1PPP A;  4YVA A;  2B1N A;  1U9V A;  4RF1 A;  3TMP A;  3LXS A;  1PE6 A;  4W5C A;  2F1G A;  1EWM A;  3KFQ A;  4XZX A;  4CDC B;  1BQI A;  2G6D A;  2YJ8 A;  2E00 A;  4CDE B;  1EWO A;  3MOR A;  1FH0 A;  1MIR A;  3TRK A;  4XUI A;  2DC6 A;  4P16 A;  1HUC B;  1BGO A;  1AYU A;  1ATK A;  3HWN A;  3HHA A;  2R9C A;  1IWD A;  2UZJ A;  1SP4 B;  3W31 A;  4BS6 A;  2Y6E A;  1AYW A;  3O1G A;  1KFX L;  3OF8 A;  3OVX A;  1EWP A;  4YYW A;  5JH3 A;  4N8W A;  1QMY A;  3BB7 A;  4RF0 A;  4REZ A;  2G8E A;  2DC7 A;  2HHN A;  4PI3 A;  3QSD A;  7PCK A;  1Q6K A;  3BBA A;  1NPZ A;  2YJ9 A;  3HHI A;  4Q8G A;  4N79 A;  2DZY A;  1YZB A;  4QH6 A;  4RY2 A;  2G8J A;  2PNS A;  1K3B B;  1GMY A;  3QT4 A;  3BPM A;  3PHW A;  4FJC A;  2JQF R;  3IHP A;  2HWK A;  5JZE A;  8PCH A;  3K9M A;  4AXL A;  1CPJ A;  2DCC A;  2NQG A;  1CS8 A;  2R9N A;  2JRI A;  3PSE A;  5CVM A;  2FRA A;  3RVV A;  1CSB B;  2ATO A;  3GCB A;  3MHS A;  4KLB A;  3BCN A;  3KKU A;  4P6G A;  3BWK A;  3IMA A;  4D8B A;  5CHV A;  3W30 A;  4AXM A;  3U8E A;  2YJ2 A;  3BPF A;  4D8E A;  3D6S A;  4X6I A;  3MP2 A;  4ZUX U;  1YAL A;  2P86 A;  1U9Q X;  2NQI A;  3BC3 A;  1S4V A;  4HWY A;  1KHP A;  4PP1 A;  3KX1 A;  4BOU A;  3N3K A;  1KXR A;  4IUM A;  3K24 A;  2HH5 A;  3IEJ A;  5CHT A;  2H7J A;  5EZQ A;  3P5W A;  1PPD A;  2PBH A;  4YYQ A;  2G7Y A;  4MI7 A;  4XR7 A;  5A24 A;  5PAD A;  2PAD A;  4BPV A;  4OVZ A;  3RVX A;  1F2B A;  1PIP A;  1ME4 A;  2B1M A;  3S3R A;  3DF0 A;  1GCB A;  2ARY A; 
#chains in the Genus database with same CATH homology
 4OW0 A;  2BTW B;  3BBA A;  1YZB A;  3ZNH A;  4GUA A;  3O65 A;  4RNA A;  4BOZ A;  4PT5 A;  2JTC A;  5EZS A;  4R3D A;  3PHW A;  3RNV A;  3C0R A;  4RKX A;  2HWK A;  5JZE A;  5E6J A;  4OVZ B;  1DKI A;  2BTW A;  3PT2 A;  4A5U A;  4WUR A;  2JRI A;  3PSE A;  4HXD B;  3E9S A;  3MTV A;  4BOS A;  5KO3 A;  4D8B A;  3W30 A;  3PRM A;  4RF1 A;  3TMP A;  2FE8 A;  4D8E A;  4ZTB A;  3PHU A;  2DOS A;  3MP2 A;  4XZX A;  1UKF A;  4IP3 A;  4M0W A;  2AGA A;  3B21 A;  3OQC A;  3TRK A;  4MM3 B;  4P16 A;  4BOU A;  3BY4 A;  3IFU A;  1PVJ A;  4IUM A;  5EZQ A;  2UZJ A;  3W31 A;  2Z84 A;  4BOQ A;  3PHX A;  4MI7 A;  4BOP A;  3PRP A;  2BU3 A;  4OVZ A;  2J7Q C;  3BB7 A;  4RF0 A;  4REZ A;  3MJ5 A;  4D8I A;  2J7Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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