3PHUA

Otu domain of crimean congo hemorrhagic fever virus
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
184
structure length
183
Chain Sequence
b'PMDFLRSLDWTQVIAGQYVSNPRFNISDYFEIVRQPGDGNFYHSIAELTMPNKTDHSYHYIKRLTESAARKYYQEEPEARLVGLSLEDYLKRMLSDNEWGSTLEASMLAKEMGITIIIWTVAASDEVEAGIKFGDGDVFTAVNLLHSGQTHFDALRILPQFETDTREALSLMDRVIAVDQLTS'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords RNA-directed RNA polymerase L
publication title Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains.
pubmed doi rcsb
source organism Crimean-congo hemorrhagic fever virus strain ibar10200
molecule tags Hydrolase
total genus 58
structure length 183
sequence length 184
chains with identical sequence B
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 2010-11-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02338 OTU OTU-like cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.80 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cathepsin B; Chain A 3phuA01
3C0RA 3BY4A 4HXDB 3PT2A 3PSEA 4BOZA 3PRMA 4BOQA 4BOUA 3ZNHA 4BOSA 3PHXA 3PHUA 3TMPA 5JZEA 3PRPA 4BOPA 3PHWA
chains in the Genus database with same CATH superfamily
2E01A 1ICFA 2AIMA 2BDLA 1M6DA 5E6JA 3KKUA 1U9XA 3H7DA 3IHPA 3BY4A 4BS6A 1QMYA 2AU1A 4N4ZA 4OELA 3P5WA 3KSEA 3E9SA 3P5VA 2R9MA 1PXVA 2HD5A 4CDCB 2HH5A 4OEMA 2C0YA 2H7JA 4RY2A 4YYQA 2DCCA 1MEGA 1QDQA 1BP4A 1PPOA 8PCHA 4D8EA 3H6SA 4HWYA 4OVZA 3E1ZB 1K3BB 3NHEA 2R9CA 1KXRA 2UZJA 4Q8HA 1Y4HA 1ZCMA 2BU3A 3H89A 4QBBA 4YYSA 2XU3A 3BBAA 3O0UA 1CS8A 1ZIVA 1NPZA 4DMYA 4MZSA 1F29A 1CQDA 1AECA 1Y08A 2YJCA 2HXZA 1YK7A 3OISA 4PP2E 1ME4A 4BSQA 4P6GA 3QSDA 4Q8GA 4HXDB 2JQGR 4A5UA 2P0RA 3BPMA 4X6IA 1AU0A 2JRIA 4RKXA 2F1GA 3IFUA 3TNXA 1GCBA 2VHSA 1YZBA 2GFOA 1DKIA 2ATOA 4CDFB 2Y6EA 1KHQA 1CPJA 2OP3A 5KO3A 1YT7A 5JH3A 3WXFA 4YV8A 2AS8A 3M99A 3MHSA 1PPPA 4QRGA 1AYUA 5F02A 1VJVA 2DCAA 3OQCA 1Q6KA 5J94A 4FIPA 2G6DA 1A6RA 4K7CA 1AIMA 4PADA 1NLJA 1S4VA 4PI3A 4GUAA 2P7UA 1EF7A 1KFXL 1F2AA 2FRQA 1YALA 1STFE 2CIOA 1IWDA 3PHUA 3PRPA 2BTWA 5A24A 1CVZA 4KLBA 2NQDB 3CBKA 3TRKA 2OZ2A 4W5BA 3ZNHA 2NQIA 4IUMA 3BC3A 2AYNA 3IV2A 4D8BA 3C0RA 4M0WA 3KFQA 1MS6A 4D8IA 3PRMA 3V6CA 3PBHA 1PE6A 1PPDA 2DC8A 2BDZA 1UKFA 3BOWA 3PW3A 2G8JA 3C9EA 2DZYA 3H8CA 4YYRA 3HD3A 2YJ2A 2DJFB 1MDWA 3MJ5A 1ME3A 2O6XA 4MZOA 1U5IA 3MTVA 4I07A 1BQIA 4BOZA 4YYVA 1X9YA 4BPVA 3KWZA 3P5XA 1AYWA 4FJCA 3RNVA 5CVOB 4YYWA 4P16A 1YVBA 1F2BA 3MP2A 4X6HA 3N3KA 2Y5BA 2Z84A 4BOUA 2FRAA 2AVWA 1AU3A 1PBHA 1TLOA 1DF0A 1NL6A 4QH6A 3D6SA 3F5VA 3AI8A 3PHWA 3PDFA 2AUZA 3CH3X 3H8BA 3K8UA 1PPNA 3N3GA 4N79A 5JZEA 1FH0A 1GMYA 2PNSA 2YJ9A 3PSEA 4XZXA 1F2CA 5CHVA 2BTWB 2FTDA 4PP1A 3B21A 2WBFX 1YK8A 4REZA 3S3QA 3P5UA 3K24A 4I05A 3IOQA 3WXGA 1MIRA 4I04A 2FYEA 4RF1A 5K16A 3LXSA 3O1GA 3BPFA 1THEA 4XR7A 3RVWA 2IPPB 3USVA 9PAPA 2OULA 2FE8A 3HHAA 3O65A 5EZSA 3OVZA 3IMAA 4WURA 3F75A 2NQGA 2YJ8A 2FT2A 2AGAA 3KWBX 1NQCA 5CVNB 3WXEA 2AUXA 2DC6A 4QRVA 3QJ3A 4CDEB 4AXLA 4OVZB 1POPA 2XU4A 4CZWA 5EZQA 3LFYA 4MI7A 1VSNA 4YVAA 2G8EA 1KHPA 4QRXA 2VHFA 3MORA 1GLOA 3IEJA 4WA6A 1PCIA 1CTEA 4BOPA 1AU4A 4W4UA 3BWKA 3IUTA 3HHIA 1ATKA 1MEMA 1CJLA 2XU5A 3HWNA 4P6EA 5CVMA 3RVXA 2FQ9A 2E00A 4G54A 3ZUAA 3TMPA 3MTNA 2GHUA 3RVVA 1XKGA 2JQFR 2R6NA 2J7QC 3I3TA 3U8EA 1QOLA 2DCBA 2P86A 1CB5A 3I06A 2ARYA 2DZZA 3KW9A 4MM3B 2IBIA 3MHHA 3S3RA 4X6JA 4CDDB 1AYVA 1EWMA 3BCNA 4FK5A 4ZTBA 1SP4B 2B1MA 1PVJA 2E03A 1KFUL 3KX1A 4BOSA 3GCBA 4N8WA 3W30A 3OF8A 2FO5A 3ERVA 3V6EA 1HUCB 1U9QX 4BS5A 2DCDA 2FUDA 4OW0A 2HWKA 5EGWA 1AU2A 4W5CA 1JQPA 4DMXA 1U9WA 1ITOA 1PIPA 1TL9A 1CV8A 1EWLA 2DC9A 2J7QA 1NB3A 1TU6A 3K9MA 2YJBA 3W31A 4BOQA 4ZUXU 2ACTA 2PADA 2NQAA 5FPWA 1BGOA 3N4CA 1SNKA 4PT5A 1BY8A 2DC7A 2XU1A 3OF9A 3PT2A 2E02A 4RNAA 3DF0A 3PHXA 2G7YA 2F7DA 4BQVA 2AYOA 2HHNA 5CHTA 4XUIA 5JA7A 3CBJA 3QT4A 7PCKA 1U9VA 2PREA 1QXPA 5PADA 1EWOA 4YYUA 1PADA 3CH2X 3PNRA 1NB5A 6PADA 1DEUA 3BB7A 4AXMA 1CSBB 2B1NA 4RF0A 1EWPA 1GECE 2DJGB 2JTCA 5EF4A 2R9OA 3B79A 2R9NA 3OVXA 4R3DA 2PBHA 1O0EA 2DOSA 2CB5A 2R9FA 4IP3A 1MHWA 4MSXA
chains in the Genus database with same CATH topology
2J7QC 5E6JA 3PHWA 4GUAA 3BY4A 4MM3B 5JZEA 3E9SA 4ZTBA 3PSEA 4XZXA 1PVJA 2BTWB 4BOSA 3PHUA 3PRPA 2BTWA 3W30A 3B21A 4REZA 3TRKA 3ZNHA 4OW0A 2HWKA 4IUMA 4D8EA 4RF1A 4OVZA 4D8BA 3C0RA 4M0WA 4D8IA 3PRMA 2J7QA 2FE8A 2UZJA 3W31A 4BOQA 3O65A 2BU3A 5EZSA 4WURA 3BBAA 4PT5A 1UKFA 2AGAA 3PT2A 4RNAA 4OVZB 3PHXA 5EZQA 3MJ5A 4MI7A 3MTVA 4HXDB 4BOZA 4A5UA 2JRIA 4RKXA 3IFUA 1YZBA 3RNVA 1DKIA 4BOPA 3BB7A 5KO3A 4P16A 4RF0A 2JTCA 3MP2A 4R3DA 2Z84A 4BOUA 2DOSA 3OQCA 4IP3A 3TMPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3C0R A;  3BY4 A;  4HXD B;  3PT2 A;  3PSE A;  4BOZ A;  3PRM A;  4BOQ A;  4BOU A;  3ZNH A;  4BOS A;  3PHX A;  3PHU A;  3TMP A;  5JZE A;  3PRP A;  4BOP A;  3PHW A; 
#chains in the Genus database with same CATH topology
 2E01 A;  1ICF A;  2AIM A;  2BDL A;  1M6D A;  5E6J A;  3KKU A;  1U9X A;  3H7D A;  3IHP A;  3BY4 A;  4BS6 A;  1QMY A;  2AU1 A;  4N4Z A;  4OEL A;  3P5W A;  3KSE A;  3E9S A;  3P5V A;  2R9M A;  1PXV A;  2HD5 A;  4CDC B;  2HH5 A;  4OEM A;  2C0Y A;  2H7J A;  4RY2 A;  4YYQ A;  2DCC A;  1MEG A;  1QDQ A;  1BP4 A;  1PPO A;  8PCH A;  4D8E A;  3H6S A;  4HWY A;  4OVZ A;  3E1Z B;  1K3B B;  3NHE A;  2R9C A;  1KXR A;  2UZJ A;  4Q8H A;  1Y4H A;  1ZCM A;  2BU3 A;  3H89 A;  4QBB A;  4YYS A;  2XU3 A;  3BBA A;  3O0U A;  1CS8 A;  1ZIV A;  1NPZ A;  4DMY A;  4MZS A;  1F29 A;  1CQD A;  1AEC A;  1Y08 A;  2YJC A;  2HXZ A;  1YK7 A;  3OIS A;  4PP2 E;  1ME4 A;  4BSQ A;  4P6G A;  3QSD A;  4Q8G A;  4HXD B;  2JQG R;  4A5U A;  2P0R A;  3BPM A;  4X6I A;  1AU0 A;  2JRI A;  4RKX A;  2F1G A;  3IFU A;  3TNX A;  1GCB A;  2VHS A;  1YZB A;  2GFO A;  1DKI A;  2ATO A;  4CDF B;  2Y6E A;  1KHQ A;  1CPJ A;  2OP3 A;  5KO3 A;  1YT7 A;  5JH3 A;  3WXF A;  4YV8 A;  2AS8 A;  3M99 A;  3MHS A;  1PPP A;  4QRG A;  1AYU A;  5F02 A;  1VJV A;  2DCA A;  3OQC A;  1Q6K A;  5J94 A;  4FIP A;  2G6D A;  1A6R A;  4K7C A;  1AIM A;  4PAD A;  1NLJ A;  1S4V A;  4PI3 A;  4GUA A;  2P7U A;  1EF7 A;  1KFX L;  1F2A A;  2FRQ A;  1YAL A;  1STF E;  2CIO A;  1IWD A;  3PHU A;  3PRP A;  2BTW A;  5A24 A;  1CVZ A;  4KLB A;  2NQD B;  3CBK A;  3TRK A;  2OZ2 A;  4W5B A;  3ZNH A;  2NQI A;  4IUM A;  3BC3 A;  2AYN A;  3IV2 A;  4D8B A;  3C0R A;  4M0W A;  3KFQ A;  1MS6 A;  4D8I A;  3PRM A;  3V6C A;  3PBH A;  1PE6 A;  1PPD A;  2DC8 A;  2BDZ A;  1UKF A;  3BOW A;  3PW3 A;  2G8J A;  3C9E A;  2DZY A;  3H8C A;  4YYR A;  3HD3 A;  2YJ2 A;  2DJF B;  1MDW A;  3MJ5 A;  1ME3 A;  2O6X A;  4MZO A;  1U5I A;  3MTV A;  4I07 A;  1BQI A;  4BOZ A;  4YYV A;  1X9Y A;  4BPV A;  3KWZ A;  3P5X A;  1AYW A;  4FJC A;  3RNV A;  5CVO B;  4YYW A;  4P16 A;  1YVB A;  1F2B A;  3MP2 A;  4X6H A;  3N3K A;  2Y5B A;  2Z84 A;  4BOU A;  2FRA A;  2AVW A;  1AU3 A;  1PBH A;  1TLO A;  1DF0 A;  1NL6 A;  4QH6 A;  3D6S A;  3F5V A;  3AI8 A;  3PHW A;  3PDF A;  2AUZ A;  3CH3 X;  3H8B A;  3K8U A;  1PPN A;  3N3G A;  4N79 A;  5JZE A;  1FH0 A;  1GMY A;  2PNS A;  2YJ9 A;  3PSE A;  4XZX A;  1F2C A;  5CHV A;  2BTW B;  2FTD A;  4PP1 A;  3B21 A;  2WBF X;  1YK8 A;  4REZ A;  3S3Q A;  3P5U A;  3K24 A;  4I05 A;  3IOQ A;  3WXG A;  1MIR A;  4I04 A;  2FYE A;  4RF1 A;  5K16 A;  3LXS A;  3O1G A;  3BPF A;  1THE A;  4XR7 A;  3RVW A;  2IPP B;  3USV A;  9PAP A;  2OUL A;  2FE8 A;  3HHA A;  3O65 A;  5EZS A;  3OVZ A;  3IMA A;  4WUR A;  3F75 A;  2NQG A;  2YJ8 A;  2FT2 A;  2AGA A;  3KWB X;  1NQC A;  5CVN B;  3WXE A;  2AUX A;  2DC6 A;  4QRV A;  3QJ3 A;  4CDE B;  4AXL A;  4OVZ B;  1POP A;  2XU4 A;  4CZW A;  5EZQ A;  3LFY A;  4MI7 A;  1VSN A;  4YVA A;  2G8E A;  1KHP A;  4QRX A;  2VHF A;  3MOR A;  1GLO A;  3IEJ A;  4WA6 A;  1PCI A;  1CTE A;  4BOP A;  1AU4 A;  4W4U A;  3BWK A;  3IUT A;  3HHI A;  1ATK A;  1MEM A;  1CJL A;  2XU5 A;  3HWN A;  4P6E A;  5CVM A;  3RVX A;  2FQ9 A;  2E00 A;  4G54 A;  3ZUA A;  3TMP A;  3MTN A;  2GHU A;  3RVV A;  1XKG A;  2JQF R;  2R6N A;  2J7Q C;  3I3T A;  3U8E A;  1QOL A;  2DCB A;  2P86 A;  1CB5 A;  3I06 A;  2ARY A;  2DZZ A;  3KW9 A;  4MM3 B;  2IBI A;  3MHH A;  3S3R A;  4X6J A;  4CDD B;  1AYV A;  1EWM A;  3BCN A;  4FK5 A;  4ZTB A;  1SP4 B;  2B1M A;  1PVJ A;  2E03 A;  1KFU L;  3KX1 A;  4BOS A;  3GCB A;  4N8W A;  3W30 A;  3OF8 A;  2FO5 A;  3ERV A;  3V6E A;  1HUC B;  1U9Q X;  4BS5 A;  2DCD A;  2FUD A;  4OW0 A;  2HWK A;  5EGW A;  1AU2 A;  4W5C A;  1JQP A;  4DMX A;  1U9W A;  1ITO A;  1PIP A;  1TL9 A;  1CV8 A;  1EWL A;  2DC9 A;  2J7Q A;  1NB3 A;  1TU6 A;  3K9M A;  2YJB A;  3W31 A;  4BOQ A;  4ZUX U;  2ACT A;  2PAD A;  2NQA A;  5FPW A;  1BGO A;  3N4C A;  1SNK A;  4PT5 A;  1BY8 A;  2DC7 A;  2XU1 A;  3OF9 A;  3PT2 A;  2E02 A;  4RNA A;  3DF0 A;  3PHX A;  2G7Y A;  2F7D A;  4BQV A;  2AYO A;  2HHN A;  5CHT A;  4XUI A;  5JA7 A;  3CBJ A;  3QT4 A;  7PCK A;  1U9V A;  2PRE A;  1QXP A;  5PAD A;  1EWO A;  4YYU A;  1PAD A;  3CH2 X;  3PNR A;  1NB5 A;  6PAD A;  1DEU A;  3BB7 A;  4AXM A;  1CSB B;  2B1N A;  4RF0 A;  1EWP A;  1GEC E;  2DJG B;  2JTC A;  5EF4 A;  2R9O A;  3B79 A;  2R9N A;  3OVX A;  4R3D A;  2PBH A;  1O0E A;  2DOS A;  2CB5 A;  2R9F A;  4IP3 A;  1MHW A;  4MSX A; 
#chains in the Genus database with same CATH homology
 2J7Q C;  5E6J A;  3PHW A;  4GUA A;  3BY4 A;  4MM3 B;  5JZE A;  3E9S A;  4ZTB A;  3PSE A;  4XZX A;  1PVJ A;  2BTW B;  4BOS A;  3PHU A;  3PRP A;  2BTW A;  3W30 A;  3B21 A;  4REZ A;  3TRK A;  3ZNH A;  4OW0 A;  2HWK A;  4IUM A;  4D8E A;  4RF1 A;  4OVZ A;  4D8B A;  3C0R A;  4M0W A;  4D8I A;  3PRM A;  2J7Q A;  2FE8 A;  2UZJ A;  3W31 A;  4BOQ A;  3O65 A;  2BU3 A;  5EZS A;  4WUR A;  3BBA A;  4PT5 A;  1UKF A;  2AGA A;  3PT2 A;  4RNA A;  4OVZ B;  3PHX A;  5EZQ A;  3MJ5 A;  4MI7 A;  3MTV A;  4HXD B;  4BOZ A;  4A5U A;  2JRI A;  4RKX A;  3IFU A;  1YZB A;  3RNV A;  1DKI A;  4BOP A;  3BB7 A;  5KO3 A;  4P16 A;  4RF0 A;  2JTC A;  3MP2 A;  4R3D A;  2Z84 A;  4BOU A;  2DOS A;  3OQC A;  4IP3 A;  3TMP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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