3PHUA

Otu domain of crimean congo hemorrhagic fever virus
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
184
structure length
183
Chain Sequence
PMDFLRSLDWTQVIAGQYVSNPRFNISDYFEIVRQPGDGNFYHSIAELTMPNKTDHSYHYIKRLTESAARKYYQEEPEARLVGLSLEDYLKRMLSDNEWGSTLEASMLAKEMGITIIIWTVAASDEVEAGIKFGDGDVFTAVNLLHSGQTHFDALRILPQFETDTREALSLMDRVIAVDQLTS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords RNA-directed RNA polymerase L
publication title Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains.
pubmed doi rcsb
source organism Crimean-congo hemorrhagic fever virus strain ibar10200
total genus 58
structure length 183
sequence length 184
chains with identical sequence B
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 2010-11-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02338 OTU OTU-like cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.80 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cathepsin B; Chain A 3phuA01
4BOSA 3PHWA 3PHUA 4BOUA 3PRMA 3PRPA 3PT2A 4BOZA 3ZNHA 5JZEA 3PSEA 3PHXA 4BOPA 3C0RA 3TMPA 4BOQA 4HXDB 3BY4A
chains in the Genus database with same CATH superfamily
1PPNA 1MDWA 1YK7A 5PADA 3I3TA 3BY4A 1PADA 1JQPA 1VSNA 3O1GA 1ITOA 2BU3A 3I06A 1YVBA 3BC3A 3P5WA 4QRVA 1X9YA 1ZCMA 1CVZA 1THEA 3B79A 3KKUA 3ZNHA 2BTWB 2JQFR 3HD3A 5JA7A 3MTVA 4RF1A 2AU1A 2HWKA 1CPJA 4AXLA 2DC8A 2DJGB 1EWMA 4P6GA 4ZUXU 4BOQA 4DMXA 2NQDB 3GCBA 4YV8A 1PBHA 1YALA 4A5UA 1AU2A 4YVAA 4N4ZA 3RVXA 2VHSA 1BQIA 3PHWA 5J94A 3IV2A 3IFUA 1AYWA 2G8EA 1DF0A 3K8UA 4PP2E 4HWYA 2DC6A 2HD5A 3U8EA 1SP4B 4I04A 2DCCA 4R3DA 9PAPA 2Z84A 3M99A 4G54A 1U9QX 4FIPA 2YJCA 3ERVA 4RF0A 2BTWA 2Y5BA 3N4CA 2DZZA 1KHPA 4RNAA 4BSQA 4OELA 4P6EA 3V6CA 4KLBA 1CV8A 3PDFA 3RVWA 1S4VA 4XR7A 2AVWA 1QMYA 1EWLA 4WA6A 4RKXA 4BOSA 4BOUA 4BPVA 4OW0A 1MEMA 3HWNA 3W30A 5EZSA 2ACTA 3N3GA 3PRMA 4MZSA 5F02A 1AU0A 3OVZA 2FTDA 1GLOA 2ARYA 3PHXA 4PADA 5EZQA 3MTNA 1GECE 1AU3A 3PHUA 3BOWA 4FJCA 3BPFA 2FE8A 1KFXL 1QXPA 1F2AA 3IUTA 5CVOB 4CDEB 4M0WA 4K7CA 4QH6A 5A24A 2R9NA 2ATOA 4WURA 2R9CA 4REZA 1F2CA 1AYVA 1DEUA 2XU4A 3TRKA 1PPDA 3E1ZB 3PBHA 1EWPA 1ME4A 1CS8A 5CHVA 1NPZA 3HHIA 3QSDA 2FRQA 1QOLA 1BP4A 3BWKA 3KSEA 3IEJA 4YYVA 1Q6KA 1BY8A 3TMPA 2DC9A 2YJ8A 2XU3A 2FYEA 5EGWA 3K9MA 4X6IA 2AUXA 2E03A 3WXEA 5KO3A 4D8EA 1STFE 2Y6EA 3LXSA 4RY2A 1MEGA 2AS8A 2B1NA 1MS6A 2WBFX 3NHEA 4W5BA 4P16A 1F2BA 3DF0A 3WXGA 3OQCA 3BBAA 2CB5A 4PT5A 2HHNA 2G6DA 1KXRA 3IHPA 3WXFA 2AYNA 2FQ9A 2PBHA 4D8BA 2XU5A 5CVNB 1Y08A 3CH3X 3IOQA 1MIRA 5K16A 1ME3A 2DCAA 3QT4A 3H7DA 4PI3A 3OF8A 5E6JA 1YZBA 8PCHA 4CDCB 5JH3A 4YYQA 1BGOA 3AI8A 2DJFB 3CH2X 5CHTA 4IP3A 3BPMA 1NB3A 2CIOA 4W4UA 5FPWA 2AUZA 6PADA 4XUIA 1PPPA 2R9FA 1CQDA 2H7JA 1KFUL 4HXDB 2R6NA 1POPA 4W5CA 3P5UA 1DKIA 2C0YA 1TLOA 1GCBA 5JZEA 3PSEA 3P5XA 3OVXA 2OP3A 1PXVA 3BB7A 2AYOA 2NQGA 3PT2A 4I05A 1CSBB 1MHWA 2PREA 3O0UA 4X6HA 2VHFA 4IUMA 4I07A 4X6JA 1NB5A 4PP1A 2YJ9A 1GMYA 1AU4A 2FO5A 2GHUA 4YYSA 2AIMA 1HUCB 2E00A 1YT7A 4QRGA 1NLJA 1NL6A 4OVZB 2NQAA 2E02A 4CDFB 3KWZA 3S3QA 3W31A 4GUAA 2FRAA 1O0EA 4ZTBA 3PW3A 2OULA 3C0RA 2P86A 1FH0A 4D8IA 3S3RA 3B21A 3KWBX 4YYWA 3KX1A 2G8JA 2R9OA 2P7UA 1Y4HA 1QDQA 2DZYA 1TU6A 2FT2A 4DMYA 1U5IA 1XKGA 3IMAA 3USVA 1AIMA 1CB5A 2OZ2A 3KW9A 1VJVA 3LFYA 4OVZA 3F5VA 4Q8GA 3TNXA 4QBBA 3E9SA 3MP2A 2BDLA 1ICFA 3K24A 3PRPA 4FK5A 3N3KA 2BDZA 4BS6A 1U9VA 2B1MA 4N8WA 2NQIA 2PNSA 2YJBA 3P5VA 1EWOA 1M6DA 1PPOA 1U9WA 1PE6A 4BOZA 2P0RA 3MORA 1SNKA 1IWDA 2JRIA 1PVJA 3QJ3A 3MHHA 1K3BB 1AYUA 2DC7A 1PCIA 2HXZA 4MZOA 2F1GA 4CDDB 2FUDA 2IPPB 2DCBA 1U9XA 4MM3B 4XZXA 3V6EA 1ATKA 2J7QC 3CBKA 1ZIVA 3RNVA 4CZWA 3HHAA 3H89A 4MSXA 2GFOA 1PIPA 4BS5A 1TL9A 1AECA 2HH5A 2J7QA 4BQVA 3OISA 3H8CA 3OF9A 2XU1A 3ZUAA 3KFQA 2JTCA 5CVMA 4YYRA 3H8BA 3RVVA 3C9EA 2IBIA 2DCDA 1YK8A 2F7DA 3CBJA 3MHSA 1EF7A 3F75A 2E01A 4AXMA 2O6XA 3D6SA 3MJ5A 1CTEA 1F29A 2G7YA 3BCNA 2DOSA 4BOPA 4OEMA 2UZJA 4Q8HA 1KHQA 2YJ2A 4QRXA 1UKFA 4N79A 2PADA 1NQCA 1A6RA 4YYUA 2AGAA 2JQGR 7PCKA 5EF4A 4MI7A 3O65A 3PNRA 1CJLA 2R9MA 3H6SA
chains in the Genus database with same CATH topology
3PRPA 3PHXA 5EZQA 3BY4A 3PHUA 2FE8A 4HXDB 2BU3A 1DKIA 4M0WA 4WURA 4BOZA 3ZNHA 4REZA 5JZEA 3PSEA 2BTWB 3TRKA 3BB7A 3MTVA 3PT2A 4RF1A 2JRIA 1PVJA 2HWKA 4IUMA 4MM3B 4BOQA 4XZXA 2J7QC 3RNVA 4A5UA 3TMPA 3PHWA 2J7QA 4OVZB 3IFUA 5KO3A 2JTCA 3W31A 4GUAA 4D8EA 4ZTBA 3C0RA 4R3DA 2Z84A 4D8IA 4P16A 3B21A 4RF0A 2BTWA 3OQCA 3BBAA 4PT5A 3MJ5A 4BOPA 2DOSA 4RNAA 4D8BA 2UZJA 1UKFA 4RKXA 2AGAA 4BOSA 4BOUA 4OW0A 4OVZA 4MI7A 3O65A 5E6JA 1YZBA 3W30A 5EZSA 3E9SA 3PRMA 3MP2A 4IP3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BOS A;  3PHW A;  3PHU A;  4BOU A;  3PRM A;  3PRP A;  3PT2 A;  4BOZ A;  3ZNH A;  5JZE A;  3PSE A;  3PHX A;  4BOP A;  3C0R A;  3TMP A;  4BOQ A;  4HXD B;  3BY4 A; 
#chains in the Genus database with same CATH topology
 1PPN A;  1MDW A;  1YK7 A;  5PAD A;  3I3T A;  3BY4 A;  1PAD A;  1JQP A;  1VSN A;  3O1G A;  1ITO A;  2BU3 A;  3I06 A;  1YVB A;  3BC3 A;  3P5W A;  4QRV A;  1X9Y A;  1ZCM A;  1CVZ A;  1THE A;  3B79 A;  3KKU A;  3ZNH A;  2BTW B;  2JQF R;  3HD3 A;  5JA7 A;  3MTV A;  4RF1 A;  2AU1 A;  2HWK A;  1CPJ A;  4AXL A;  2DC8 A;  2DJG B;  1EWM A;  4P6G A;  4ZUX U;  4BOQ A;  4DMX A;  2NQD B;  3GCB A;  4YV8 A;  1PBH A;  1YAL A;  4A5U A;  1AU2 A;  4YVA A;  4N4Z A;  3RVX A;  2VHS A;  1BQI A;  3PHW A;  5J94 A;  3IV2 A;  3IFU A;  1AYW A;  2G8E A;  1DF0 A;  3K8U A;  4PP2 E;  4HWY A;  2DC6 A;  2HD5 A;  3U8E A;  1SP4 B;  4I04 A;  2DCC A;  4R3D A;  9PAP A;  2Z84 A;  3M99 A;  4G54 A;  1U9Q X;  4FIP A;  2YJC A;  3ERV A;  4RF0 A;  2BTW A;  2Y5B A;  3N4C A;  2DZZ A;  1KHP A;  4RNA A;  4BSQ A;  4OEL A;  4P6E A;  3V6C A;  4KLB A;  1CV8 A;  3PDF A;  3RVW A;  1S4V A;  4XR7 A;  2AVW A;  1QMY A;  1EWL A;  4WA6 A;  4RKX A;  4BOS A;  4BOU A;  4BPV A;  4OW0 A;  1MEM A;  3HWN A;  3W30 A;  5EZS A;  2ACT A;  3N3G A;  3PRM A;  4MZS A;  5F02 A;  1AU0 A;  3OVZ A;  2FTD A;  1GLO A;  2ARY A;  3PHX A;  4PAD A;  5EZQ A;  3MTN A;  1GEC E;  1AU3 A;  3PHU A;  3BOW A;  4FJC A;  3BPF A;  2FE8 A;  1KFX L;  1QXP A;  1F2A A;  3IUT A;  5CVO B;  4CDE B;  4M0W A;  4K7C A;  4QH6 A;  5A24 A;  2R9N A;  2ATO A;  4WUR A;  2R9C A;  4REZ A;  1F2C A;  1AYV A;  1DEU A;  2XU4 A;  3TRK A;  1PPD A;  3E1Z B;  3PBH A;  1EWP A;  1ME4 A;  1CS8 A;  5CHV A;  1NPZ A;  3HHI A;  3QSD A;  2FRQ A;  1QOL A;  1BP4 A;  3BWK A;  3KSE A;  3IEJ A;  4YYV A;  1Q6K A;  1BY8 A;  3TMP A;  2DC9 A;  2YJ8 A;  2XU3 A;  2FYE A;  5EGW A;  3K9M A;  4X6I A;  2AUX A;  2E03 A;  3WXE A;  5KO3 A;  4D8E A;  1STF E;  2Y6E A;  3LXS A;  4RY2 A;  1MEG A;  2AS8 A;  2B1N A;  1MS6 A;  2WBF X;  3NHE A;  4W5B A;  4P16 A;  1F2B A;  3DF0 A;  3WXG A;  3OQC A;  3BBA A;  2CB5 A;  4PT5 A;  2HHN A;  2G6D A;  1KXR A;  3IHP A;  3WXF A;  2AYN A;  2FQ9 A;  2PBH A;  4D8B A;  2XU5 A;  5CVN B;  1Y08 A;  3CH3 X;  3IOQ A;  1MIR A;  5K16 A;  1ME3 A;  2DCA A;  3QT4 A;  3H7D A;  4PI3 A;  3OF8 A;  5E6J A;  1YZB A;  8PCH A;  4CDC B;  5JH3 A;  4YYQ A;  1BGO A;  3AI8 A;  2DJF B;  3CH2 X;  5CHT A;  4IP3 A;  3BPM A;  1NB3 A;  2CIO A;  4W4U A;  5FPW A;  2AUZ A;  6PAD A;  4XUI A;  1PPP A;  2R9F A;  1CQD A;  2H7J A;  1KFU L;  4HXD B;  2R6N A;  1POP A;  4W5C A;  3P5U A;  1DKI A;  2C0Y A;  1TLO A;  1GCB A;  5JZE A;  3PSE A;  3P5X A;  3OVX A;  2OP3 A;  1PXV A;  3BB7 A;  2AYO A;  2NQG A;  3PT2 A;  4I05 A;  1CSB B;  1MHW A;  2PRE A;  3O0U A;  4X6H A;  2VHF A;  4IUM A;  4I07 A;  4X6J A;  1NB5 A;  4PP1 A;  2YJ9 A;  1GMY A;  1AU4 A;  2FO5 A;  2GHU A;  4YYS A;  2AIM A;  1HUC B;  2E00 A;  1YT7 A;  4QRG A;  1NLJ A;  1NL6 A;  4OVZ B;  2NQA A;  2E02 A;  4CDF B;  3KWZ A;  3S3Q A;  3W31 A;  4GUA A;  2FRA A;  1O0E A;  4ZTB A;  3PW3 A;  2OUL A;  3C0R A;  2P86 A;  1FH0 A;  4D8I A;  3S3R A;  3B21 A;  3KWB X;  4YYW A;  3KX1 A;  2G8J A;  2R9O A;  2P7U A;  1Y4H A;  1QDQ A;  2DZY A;  1TU6 A;  2FT2 A;  4DMY A;  1U5I A;  1XKG A;  3IMA A;  3USV A;  1AIM A;  1CB5 A;  2OZ2 A;  3KW9 A;  1VJV A;  3LFY A;  4OVZ A;  3F5V A;  4Q8G A;  3TNX A;  4QBB A;  3E9S A;  3MP2 A;  2BDL A;  1ICF A;  3K24 A;  3PRP A;  4FK5 A;  3N3K A;  2BDZ A;  4BS6 A;  1U9V A;  2B1M A;  4N8W A;  2NQI A;  2PNS A;  2YJB A;  3P5V A;  1EWO A;  1M6D A;  1PPO A;  1U9W A;  1PE6 A;  4BOZ A;  2P0R A;  3MOR A;  1SNK A;  1IWD A;  2JRI A;  1PVJ A;  3QJ3 A;  3MHH A;  1K3B B;  1AYU A;  2DC7 A;  1PCI A;  2HXZ A;  4MZO A;  2F1G A;  4CDD B;  2FUD A;  2IPP B;  2DCB A;  1U9X A;  4MM3 B;  4XZX A;  3V6E A;  1ATK A;  2J7Q C;  3CBK A;  1ZIV A;  3RNV A;  4CZW A;  3HHA A;  3H89 A;  4MSX A;  2GFO A;  1PIP A;  4BS5 A;  1TL9 A;  1AEC A;  2HH5 A;  2J7Q A;  4BQV A;  3OIS A;  3H8C A;  3OF9 A;  2XU1 A;  3ZUA A;  3KFQ A;  2JTC A;  5CVM A;  4YYR A;  3H8B A;  3RVV A;  3C9E A;  2IBI A;  2DCD A;  1YK8 A;  2F7D A;  3CBJ A;  3MHS A;  1EF7 A;  3F75 A;  2E01 A;  4AXM A;  2O6X A;  3D6S A;  3MJ5 A;  1CTE A;  1F29 A;  2G7Y A;  3BCN A;  2DOS A;  4BOP A;  4OEM A;  2UZJ A;  4Q8H A;  1KHQ A;  2YJ2 A;  4QRX A;  1UKF A;  4N79 A;  2PAD A;  1NQC A;  1A6R A;  4YYU A;  2AGA A;  2JQG R;  7PCK A;  5EF4 A;  4MI7 A;  3O65 A;  3PNR A;  1CJL A;  2R9M A;  3H6S A; 
#chains in the Genus database with same CATH homology
 3PRP A;  3PHX A;  5EZQ A;  3BY4 A;  3PHU A;  2FE8 A;  4HXD B;  2BU3 A;  1DKI A;  4M0W A;  4WUR A;  4BOZ A;  3ZNH A;  4REZ A;  5JZE A;  3PSE A;  2BTW B;  3TRK A;  3BB7 A;  3MTV A;  3PT2 A;  4RF1 A;  2JRI A;  1PVJ A;  2HWK A;  4IUM A;  4MM3 B;  4BOQ A;  4XZX A;  2J7Q C;  3RNV A;  4A5U A;  3TMP A;  3PHW A;  2J7Q A;  4OVZ B;  3IFU A;  5KO3 A;  2JTC A;  3W31 A;  4GUA A;  4D8E A;  4ZTB A;  3C0R A;  4R3D A;  2Z84 A;  4D8I A;  4P16 A;  3B21 A;  4RF0 A;  2BTW A;  3OQC A;  3BBA A;  4PT5 A;  3MJ5 A;  4BOP A;  2DOS A;  4RNA A;  4D8B A;  2UZJ A;  1UKF A;  4RKX A;  2AGA A;  4BOS A;  4BOU A;  4OW0 A;  4OVZ A;  4MI7 A;  3O65 A;  5E6J A;  1YZB A;  3W30 A;  5EZS A;  3E9S A;  3PRM A;  3MP2 A;  4IP3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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