3AI8A

Cathepsin b in complex with the nitroxoline
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
256
structure length
256
Chain Sequence
LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Cathepsin B
publication title Novel mechanism of cathepsin B inhibition by antibiotic nitroxoline and related compounds
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase/hydrolase inhibitor
total genus 76
structure length 256
sequence length 256
chains with identical sequence B
ec nomenclature ec 3.4.22.1: Cathepsin B.
pdb deposition date 2010-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3ai8A00
4PI3A 4CDDB 4PP1A 1NB3A 3OISA 5EF4A 5FPWA 4OEMA 4DMYA 3C9EA 5A24A 3WXGA 4RY2A 1U9VA 1ZIVA 1VJVA 2VHSA 1PADA 4YYSA 3S3QA 2NQDB 2IPPB 3H7DA 2XU4A 2HH5A 1IWDA 1A6RA 4W5CA 1CTEA 1FH0A 3H8CA 1O0EA 2BDLA 3M99A 3WXEA 1QDQA 3MTNA 1ICFA 4YYUA 2DCBA 3K9MA 4BSQA 1THEA 3NHEA 4K7CA 2G6DA 3ERVA 2NQIA 1EWOA 4MZOA 4DMXA 1CSBB 3HHIA 3RVWA 2AYOA 3OF8A 1U5IA 4FK5A 1AU4A 3HWNA 1EF7A 1PIPA 2YJ2A 3LXSA 1KFXL 4BPVA 2HHNA 1HUCB 5JH3A 4YYWA 4CZWA 3KSEA 1AYUA 2YJCA 1CB5A 1U9QX 2G8EA 4N8WA 1U9WA 3IV2A 3KWZA 8PCHA 2PNSA 2PREA 1PXVA 2ARYA 1BY8A 1PPPA 4I07A 3U8EA 3V6EA 2DCCA 2Y6EA 2PBHA 2O6XA 1QXPA 3IOQA 1CPJA 2DC9A 4YYQA 5CVNB 2AIMA 4X6IA 1XKGA 2WBFX 4XR7A 3PW3A 1PCIA 2JQGR 1CJLA 1MEGA 2Y5BA 2E02A 4CDFB 5K16A 3HD3A 2R9MA 4QRGA 4QRXA 4Q8HA 4AXLA 1MS6A 2FRQA 1YALA 1NPZA 2YJ9A 3RVVA 2P86A 1PPNA 2NQAA 2XU3A 2E01A 3BPFA 1ZCMA 4YYRA 1MHWA 1NLJA 3E1ZB 4CDEB 3PBHA 3N3KA 3I06A 3KWBX 2AVWA 3GCBA 1KHQA 2FQ9A 3RVXA 2CB5A 2JQFR 2AS8A 1BP4A 4I04A 3DF0A 4P6GA 2YJ8A 3KW9A 3O1GA 5CVMA 3OF9A 1NQCA 3QSDA 2FTDA 5CHTA 3ZUAA 1NL6A 3TNXA 5CHVA 1PPOA 3QT4A 2R9NA 2AU1A 4MSXA 2ACTA 1YT7A 2FUDA 5F02A 3O0UA 2IBIA 2FYEA 3MHHA 2E00A 1KHPA 2P7UA 3F75A 1K3BB 4ZUXU 1GECE 1EWPA 1AYWA 1M6DA 3IMAA 2NQGA 4OELA 2C0YA 1EWMA 3P5VA 1CS8A 3N3GA 4N79A 1Q6KA 3KFQA 2E03A 2FT2A 4G54A 1CVZA 3CH2X 1QOLA 1YVBA 2DC6A 4CDCB 3H89A 3LFYA 1YK8A 1MEMA 4W5BA 3BCNA 2OP3A 2DJGB 3BOWA 1TLOA 4YVAA 1SP4B 1ATKA 3N4CA 2VHFA 2DCDA 1AU2A 7PCKA 3IHPA 9PAPA 1QMYA 3PNRA 3BWKA 2R9CA 1ITOA 3CBJA 3K8UA 1TU6A 3IEJA 3QJ3A 2HXZA 3I3TA 2FO5A 2DCAA 1DEUA 1GLOA 1AIMA 2P0RA 1F2BA 1PE6A 2R9OA 1ME4A 2AUZA 5CVOB 1S4VA 1YK7A 1AU3A 3F5VA 2R9FA 5PADA 4I05A 4YYVA 3BPMA 6PADA 3V6CA 1AECA 2XU1A 4X6JA 1STFE 3OVZA 3H6SA 2GFOA 1MDWA 4PP2E 4Q8GA 3KX1A 1VSNA 1F29A 3S3RA 1GCBA 2F1GA 1AU0A 4N4ZA 3KKUA 4YV8A 2DJFB 1KFUL 2AUXA 2B1MA 4QRVA 4BQVA 4BS5A 2G8JA 1U9XA 3H8BA 2AYNA 4QH6A 1TL9A 2H7JA 2FRAA 2B1NA 3P5WA 3OVXA 5J94A 4MZSA 4FIPA 2HD5A 1F2CA 2YJBA 2DZYA 3P5UA 4WA6A 1BQIA 4AXMA 2OZ2A 1POPA 1MIRA 1Y4HA 2CIOA 3WXFA 4QBBA 1NB5A 2G7YA 5JA7A 1PBHA 5EGWA 3USVA 1PPDA 3B79A 3D6SA 1ME3A 1KXRA 1BGOA 3AI8A 3P5XA 3BC3A 4PADA 1SNKA 3HHAA 2ATOA 2DZZA 1CV8A 4HWYA 2XU5A 2DC7A 4P6EA 3CBKA 1CQDA 2GHUA 4XUIA 1JQPA 3MHSA 4BS6A 4W4UA 1EWLA 4KLBA 2OULA 1X9YA 3MORA 3CH3X 1DF0A 3IUTA 3K24A 1GMYA 2R6NA 2F7DA 1Y08A 3PDFA 4FJCA 2BDZA 1AYVA 2PADA 1F2AA 2DC8A 4X6HA
chains in the Genus database with same CATH superfamily
4RF0A 3PSEA 4PI3A 4CDDB 4PP1A 1NB3A 3OISA 5EF4A 5FPWA 4OEMA 3IFUA 4BOQA 4RF1A 4OVZB 4D8IA 4DMYA 3C9EA 5A24A 3WXGA 4RY2A 4ZTBA 1U9VA 1ZIVA 1VJVA 4RKXA 3PHUA 2VHSA 1PADA 4YYSA 3S3QA 2NQDB 2IPPB 3OQCA 3H7DA 2XU4A 2HH5A 1IWDA 1A6RA 4W5CA 1CTEA 1FH0A 3H8CA 1O0EA 2BDLA 3M99A 3WXEA 1QDQA 3MTNA 1ICFA 4YYUA 2DCBA 3K9MA 4BSQA 1THEA 3NHEA 4K7CA 2G6DA 3ERVA 2NQIA 1EWOA 4MZOA 4DMXA 4BOSA 1CSBB 3HHIA 3RVWA 4BOUA 2AYOA 3OF8A 1U5IA 4FK5A 1AU4A 3HWNA 1EF7A 1PIPA 2YJ2A 2BU3A 3LXSA 3TRKA 2UZJA 2J7QC 1KFXL 4BPVA 2HHNA 3TMPA 1HUCB 5JH3A 4YYWA 4CZWA 4WURA 3KSEA 3C0RA 1AYUA 2YJCA 2Z84A 1CB5A 1U9QX 2G8EA 4N8WA 1U9WA 3IV2A 3KWZA 8PCHA 3BB7A 2PNSA 2PREA 1PXVA 2ARYA 1BY8A 1PPPA 4I07A 3U8EA 3V6EA 1DKIA 2DCCA 2Y6EA 3BBAA 2PBHA 2O6XA 1QXPA 3IOQA 1CPJA 2DC9A 4YYQA 5CVNB 2AIMA 5E6JA 4X6IA 1XKGA 2WBFX 4XR7A 3PW3A 1UKFA 1PCIA 2JQGR 1CJLA 1MEGA 2Y5BA 2E02A 4CDFB 5K16A 3HD3A 2R9MA 4QRGA 4QRXA 4Q8HA 4AXLA 1MS6A 2FRQA 1YALA 1NPZA 2YJ9A 3RVVA 2P86A 1PPNA 2NQAA 2XU3A 2E01A 3BPFA 1ZCMA 4YYRA 1MHWA 4R3DA 1NLJA 3E1ZB 4CDEB 3PBHA 3N3KA 3I06A 3KWBX 3E9SA 2AVWA 1YZBA 3GCBA 1KHQA 2FQ9A 3RVXA 4D8BA 2CB5A 2JQFR 2AS8A 1BP4A 4I04A 3DF0A 4P6GA 2JRIA 2YJ8A 3KW9A 3O1GA 5CVMA 3OF9A 1NQCA 3QSDA 4D8EA 2FTDA 5CHTA 3ZUAA 1NL6A 3TNXA 5CHVA 1PPOA 3QT4A 2R9NA 2AU1A 2BTWA 4MSXA 2BTWB 2ACTA 1YT7A 2FUDA 5F02A 3O0UA 2IBIA 2FE8A 2FYEA 3MHHA 2E00A 1KHPA 2P7UA 3F75A 1K3BB 4ZUXU 1GECE 1EWPA 1AYWA 1M6DA 3IMAA 4IP3A 2NQGA 4OELA 2C0YA 3BY4A 1EWMA 3P5VA 1CS8A 3N3GA 4N79A 1Q6KA 3KFQA 2E03A 2FT2A 4G54A 1CVZA 3CH2X 1QOLA 1YVBA 2DC6A 3W30A 4CDCB 3H89A 3LFYA 1YK8A 5KO3A 1MEMA 4W5BA 3BCNA 2OP3A 2DJGB 3BOWA 1TLOA 4YVAA 1SP4B 1ATKA 3N4CA 2VHFA 2DCDA 1AU2A 7PCKA 3IHPA 9PAPA 1QMYA 3PNRA 3BWKA 4BOZA 2R9CA 1ITOA 4M0WA 3CBJA 3K8UA 1TU6A 3O65A 3IEJA 3QJ3A 2HXZA 2J7QA 3I3TA 2FO5A 2DCAA 1DEUA 3PRMA 1GLOA 1AIMA 2P0RA 1F2BA 1PE6A 3MP2A 2R9OA 1ME4A 3PRPA 2AUZA 3PT2A 5CVOB 1S4VA 1YK7A 4MI7A 1AU3A 3F5VA 4XZXA 2R9FA 5PADA 4I05A 4YYVA 3BPMA 6PADA 3RNVA 3V6CA 1AECA 2XU1A 4X6JA 1STFE 3OVZA 3H6SA 2GFOA 1MDWA 4PP2E 4Q8GA 4OVZA 3KX1A 4A5UA 1VSNA 1F29A 3S3RA 1GCBA 2F1GA 3MJ5A 1AU0A 4N4ZA 3KKUA 4P16A 2DJFB 4YV8A 1KFUL 2AUXA 2B1MA 3W31A 4IUMA 4QRVA 4BQVA 4BS5A 2G8JA 1U9XA 3H8BA 2AYNA 4QH6A 2JTCA 1TL9A 2H7JA 2FRAA 2B1NA 3P5WA 3OVXA 5J94A 4MZSA 4FIPA 2HD5A 1F2CA 2YJBA 2DZYA 3P5UA 1PVJA 4WA6A 1BQIA 4AXMA 2OZ2A 1POPA 4MM3B 1MIRA 1Y4HA 2CIOA 3WXFA 4QBBA 1NB5A 4RNAA 2G7YA 5JA7A 1PBHA 5EGWA 3PHWA 3USVA 1PPDA 4HXDB 3B79A 3D6SA 1ME3A 1KXRA 1BGOA 3AI8A 3P5XA 4OW0A 3BC3A 4PADA 1SNKA 3HHAA 2ATOA 2DZZA 1CV8A 5EZSA 5EZQA 2DOSA 4HWYA 4PT5A 2XU5A 3PHXA 2DC7A 4P6EA 3CBKA 1CQDA 3B21A 4GUAA 2GHUA 4XUIA 1JQPA 4REZA 3MHSA 4BS6A 5JZEA 3ZNHA 4W4UA 1EWLA 4KLBA 2OULA 1X9YA 3MORA 3CH3X 1DF0A 3IUTA 3K24A 1GMYA 3MTVA 2R6NA 2F7DA 1Y08A 2HWKA 3PDFA 2AGAA 2BDZA 4FJCA 1AYVA 2PADA 1F2AA 4BOPA 2DC8A 4X6HA
chains in the Genus database with same CATH topology
4PI3A 4CDDB 4PP1A 1NB3A 3OISA 5EF4A 5FPWA 4OEMA 4DMYA 3C9EA 5A24A 3WXGA 4RY2A 1U9VA 3LTWA 1ZIVA 1VJVA 2VHSA 1PADA 4YYSA 3S3QA 2NQDB 2IPPB 3H7DA 2XU4A 2HH5A 1IWDA 1A6RA 4W5CA 1CTEA 1FH0A 3H8CA 1O0EA 4GUZA 2BDLA 3M99A 3WXEA 1QDQA 3MTNA 1ICFA 4YYUA 2DCBA 3K9MA 4BSQA 1THEA 3NHEA 4K7CA 2G6DA 3ERVA 2NQIA 1EWOA 4MZOA 4DMXA 1CSBB 3HHIA 3RVWA 2VFBA 2AYOA 3OF8A 1U5IA 4FK5A 1AU4A 3HWNA 1EF7A 1PIPA 2YJ2A 3LXSA 1KFXL 4BPVA 2HHNA 1HUCB 5JH3A 4YYWA 4CZWA 3KSEA 1AYUA 2YJCA 1CB5A 1U9QX 1W6FA 2G8EA 4N8WA 1U9WA 3IV2A 3KWZA 8PCHA 2PNSA 2PREA 1PXVA 2ARYA 1BY8A 1PPPA 4I07A 3U8EA 3V6EA 2DCCA 2Y6EA 2PBHA 2O6XA 1QXPA 3IOQA 1W4TA 1CPJA 2DC9A 4YYQA 5CVNB 2AIMA 4X6IA 1XKGA 2WBFX 4XR7A 3PW3A 1PCIA 2JQGR 1CJLA 1GX3A 1MEGA 2Y5BA 2E02A 4CDFB 4BGFA 5K16A 3HD3A 2R9MA 4QRGA 4QRXA 4Q8HA 4AXLA 1MS6A 2FRQA 1YALA 1NPZA 2YJ9A 3RVVA 2P86A 1PPNA 2NQAA 2XU3A 2E01A 3BPFA 1ZCMA 4YYRA 1MHWA 1NLJA 3E1ZB 4CDEB 3PBHA 3N3KA 3I06A 3KWBX 2AVWA 3GCBA 1KHQA 2FQ9A 3RVXA 2CB5A 2JQFR 2AS8A 1BP4A 4I04A 3DF0A 4P6GA 2YJ8A 3KW9A 3O1GA 5CVMA 3OF9A 1NQCA 3QSDA 2FTDA 5CHTA 3ZUAA 1NL6A 3TNXA 5CHVA 1PPOA 3QT4A 2R9NA 2AU1A 4MSXA 1E2TA 2ACTA 1YT7A 2FUDA 4B55A 5F02A 3O0UA 2IBIA 2FYEA 3MHHA 2E00A 1W5RA 1KHPA 2P7UA 3F75A 1K3BB 2BSZA 4ZUXU 1GECE 1EWPA 1AYWA 1M6DA 3IMAA 2NQGA 4OELA 2C0YA 1EWMA 3P5VA 1CS8A 3N3GA 4N79A 1Q6KA 3KFQA 2E03A 2FT2A 4G54A 1CVZA 3CH2X 1QOLA 1YVBA 4C5PA 2DC6A 4CDCB 3H89A 3LFYA 1YK8A 1MEMA 4W5BA 3BCNA 2OP3A 2DJGB 3BOWA 1TLOA 4YVAA 1SP4B 1ATKA 3N4CA 2VHFA 2DCDA 1AU2A 7PCKA 3IHPA 9PAPA 1QMYA 3PNRA 3BWKA 2R9CA 1ITOA 3CBJA 3K8UA 1TU6A 3IEJA 3QJ3A 2HXZA 3I3TA 2FO5A 2DCAA 1DEUA 1GLOA 1AIMA 2P0RA 1F2BA 1PE6A 2R9OA 1ME4A 2AUZA 5CVOB 4NV8A 1S4VA 1YK7A 1AU3A 3F5VA 2R9FA 5PADA 4I05A 4YYVA 3BPMA 6PADA 3V6CA 1AECA 2XU1A 4X6JA 1STFE 3OVZA 3H6SA 2GFOA 1MDWA 4PP2E 4Q8GA 3KX1A 1VSNA 1F29A 3S3RA 1GCBA 2F1GA 1AU0A 4N4ZA 3KKUA 4YV8A 2DJFB 1KFUL 2AUXA 2B1MA 4QRVA 4BQVA 4BS5A 2G8JA 1U9XA 3H8BA 2AYNA 4QH6A 1TL9A 2H7JA 2FRAA 2B1NA 3P5WA 3OVXA 5J94A 4MZSA 4FIPA 2HD5A 1F2CA 2YJBA 2DZYA 3P5UA 4WA6A 1BQIA 4AXMA 2OZ2A 1POPA 1MIRA 1Y4HA 2CIOA 3WXFA 4QBBA 1NB5A 2G7YA 5JA7A 1PBHA 5EGWA 3USVA 1PPDA 3D9WA 3B79A 3D6SA 1ME3A 1KXRA 1BGOA 2VFCA 3AI8A 3P5XA 3BC3A 4PADA 4NV7A 1SNKA 3HHAA 2ATOA 2DZZA 1CV8A 4HWYA 2XU5A 2DC7A 4P6EA 3CBKA 1CQDA 2GHUA 4XUIA 1JQPA 3MHSA 4BS6A 4W4UA 1EWLA 4KLBA 2OULA 1X9YA 3MORA 3CH3X 1DF0A 3IUTA 3K24A 1GMYA 2R6NA 2F7DA 1Y08A 3PDFA 4FJCA 2BDZA 1AYVA 2PADA 1F2AA 2DC8A 4X6HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PI3 A;  4CDD B;  4PP1 A;  1NB3 A;  3OIS A;  5EF4 A;  5FPW A;  4OEM A;  4DMY A;  3C9E A;  5A24 A;  3WXG A;  4RY2 A;  1U9V A;  1ZIV A;  1VJV A;  2VHS A;  1PAD A;  4YYS A;  3S3Q A;  2NQD B;  2IPP B;  3H7D A;  2XU4 A;  2HH5 A;  1IWD A;  1A6R A;  4W5C A;  1CTE A;  1FH0 A;  3H8C A;  1O0E A;  2BDL A;  3M99 A;  3WXE A;  1QDQ A;  3MTN A;  1ICF A;  4YYU A;  2DCB A;  3K9M A;  4BSQ A;  1THE A;  3NHE A;  4K7C A;  2G6D A;  3ERV A;  2NQI A;  1EWO A;  4MZO A;  4DMX A;  1CSB B;  3HHI A;  3RVW A;  2AYO A;  3OF8 A;  1U5I A;  4FK5 A;  1AU4 A;  3HWN A;  1EF7 A;  1PIP A;  2YJ2 A;  3LXS A;  1KFX L;  4BPV A;  2HHN A;  1HUC B;  5JH3 A;  4YYW A;  4CZW A;  3KSE A;  1AYU A;  2YJC A;  1CB5 A;  1U9Q X;  2G8E A;  4N8W A;  1U9W A;  3IV2 A;  3KWZ A;  8PCH A;  2PNS A;  2PRE A;  1PXV A;  2ARY A;  1BY8 A;  1PPP A;  4I07 A;  3U8E A;  3V6E A;  2DCC A;  2Y6E A;  2PBH A;  2O6X A;  1QXP A;  3IOQ A;  1CPJ A;  2DC9 A;  4YYQ A;  5CVN B;  2AIM A;  4X6I A;  1XKG A;  2WBF X;  4XR7 A;  3PW3 A;  1PCI A;  2JQG R;  1CJL A;  1MEG A;  2Y5B A;  2E02 A;  4CDF B;  5K16 A;  3HD3 A;  2R9M A;  4QRG A;  4QRX A;  4Q8H A;  4AXL A;  1MS6 A;  2FRQ A;  1YAL A;  1NPZ A;  2YJ9 A;  3RVV A;  2P86 A;  1PPN A;  2NQA A;  2XU3 A;  2E01 A;  3BPF A;  1ZCM A;  4YYR A;  1MHW A;  1NLJ A;  3E1Z B;  4CDE B;  3PBH A;  3N3K A;  3I06 A;  3KWB X;  2AVW A;  3GCB A;  1KHQ A;  2FQ9 A;  3RVX A;  2CB5 A;  2JQF R;  2AS8 A;  1BP4 A;  4I04 A;  3DF0 A;  4P6G A;  2YJ8 A;  3KW9 A;  3O1G A;  5CVM A;  3OF9 A;  1NQC A;  3QSD A;  2FTD A;  5CHT A;  3ZUA A;  1NL6 A;  3TNX A;  5CHV A;  1PPO A;  3QT4 A;  2R9N A;  2AU1 A;  4MSX A;  2ACT A;  1YT7 A;  2FUD A;  5F02 A;  3O0U A;  2IBI A;  2FYE A;  3MHH A;  2E00 A;  1KHP A;  2P7U A;  3F75 A;  1K3B B;  4ZUX U;  1GEC E;  1EWP A;  1AYW A;  1M6D A;  3IMA A;  2NQG A;  4OEL A;  2C0Y A;  1EWM A;  3P5V A;  1CS8 A;  3N3G A;  4N79 A;  1Q6K A;  3KFQ A;  2E03 A;  2FT2 A;  4G54 A;  1CVZ A;  3CH2 X;  1QOL A;  1YVB A;  2DC6 A;  4CDC B;  3H89 A;  3LFY A;  1YK8 A;  1MEM A;  4W5B A;  3BCN A;  2OP3 A;  2DJG B;  3BOW A;  1TLO A;  4YVA A;  1SP4 B;  1ATK A;  3N4C A;  2VHF A;  2DCD A;  1AU2 A;  7PCK A;  3IHP A;  9PAP A;  1QMY A;  3PNR A;  3BWK A;  2R9C A;  1ITO A;  3CBJ A;  3K8U A;  1TU6 A;  3IEJ A;  3QJ3 A;  2HXZ A;  3I3T A;  2FO5 A;  2DCA A;  1DEU A;  1GLO A;  1AIM A;  2P0R A;  1F2B A;  1PE6 A;  2R9O A;  1ME4 A;  2AUZ A;  5CVO B;  1S4V A;  1YK7 A;  1AU3 A;  3F5V A;  2R9F A;  5PAD A;  4I05 A;  4YYV A;  3BPM A;  6PAD A;  3V6C A;  1AEC A;  2XU1 A;  4X6J A;  1STF E;  3OVZ A;  3H6S A;  2GFO A;  1MDW A;  4PP2 E;  4Q8G A;  3KX1 A;  1VSN A;  1F29 A;  3S3R A;  1GCB A;  2F1G A;  1AU0 A;  4N4Z A;  3KKU A;  4YV8 A;  2DJF B;  1KFU L;  2AUX A;  2B1M A;  4QRV A;  4BQV A;  4BS5 A;  2G8J A;  1U9X A;  3H8B A;  2AYN A;  4QH6 A;  1TL9 A;  2H7J A;  2FRA A;  2B1N A;  3P5W A;  3OVX A;  5J94 A;  4MZS A;  4FIP A;  2HD5 A;  1F2C A;  2YJB A;  2DZY A;  3P5U A;  4WA6 A;  1BQI A;  4AXM A;  2OZ2 A;  1POP A;  1MIR A;  1Y4H A;  2CIO A;  3WXF A;  4QBB A;  1NB5 A;  2G7Y A;  5JA7 A;  1PBH A;  5EGW A;  3USV A;  1PPD A;  3B79 A;  3D6S A;  1ME3 A;  1KXR A;  1BGO A;  3AI8 A;  3P5X A;  3BC3 A;  4PAD A;  1SNK A;  3HHA A;  2ATO A;  2DZZ A;  1CV8 A;  4HWY A;  2XU5 A;  2DC7 A;  4P6E A;  3CBK A;  1CQD A;  2GHU A;  4XUI A;  1JQP A;  3MHS A;  4BS6 A;  4W4U A;  1EWL A;  4KLB A;  2OUL A;  1X9Y A;  3MOR A;  3CH3 X;  1DF0 A;  3IUT A;  3K24 A;  1GMY A;  2R6N A;  2F7D A;  1Y08 A;  3PDF A;  4FJC A;  2BDZ A;  1AYV A;  2PAD A;  1F2A A;  2DC8 A;  4X6H A; 
#chains in the Genus database with same CATH topology
 4RF0 A;  3PSE A;  4PI3 A;  4CDD B;  4PP1 A;  1NB3 A;  3OIS A;  5EF4 A;  5FPW A;  4OEM A;  3IFU A;  4BOQ A;  4RF1 A;  4OVZ B;  4D8I A;  4DMY A;  3C9E A;  5A24 A;  3WXG A;  4RY2 A;  4ZTB A;  1U9V A;  1ZIV A;  1VJV A;  4RKX A;  3PHU A;  2VHS A;  1PAD A;  4YYS A;  3S3Q A;  2NQD B;  2IPP B;  3OQC A;  3H7D A;  2XU4 A;  2HH5 A;  1IWD A;  1A6R A;  4W5C A;  1CTE A;  1FH0 A;  3H8C A;  1O0E A;  2BDL A;  3M99 A;  3WXE A;  1QDQ A;  3MTN A;  1ICF A;  4YYU A;  2DCB A;  3K9M A;  4BSQ A;  1THE A;  3NHE A;  4K7C A;  2G6D A;  3ERV A;  2NQI A;  1EWO A;  4MZO A;  4DMX A;  4BOS A;  1CSB B;  3HHI A;  3RVW A;  4BOU A;  2AYO A;  3OF8 A;  1U5I A;  4FK5 A;  1AU4 A;  3HWN A;  1EF7 A;  1PIP A;  2YJ2 A;  2BU3 A;  3LXS A;  3TRK A;  2UZJ A;  2J7Q C;  1KFX L;  4BPV A;  2HHN A;  3TMP A;  1HUC B;  5JH3 A;  4YYW A;  4CZW A;  4WUR A;  3KSE A;  3C0R A;  1AYU A;  2YJC A;  2Z84 A;  1CB5 A;  1U9Q X;  2G8E A;  4N8W A;  1U9W A;  3IV2 A;  3KWZ A;  8PCH A;  3BB7 A;  2PNS A;  2PRE A;  1PXV A;  2ARY A;  1BY8 A;  1PPP A;  4I07 A;  3U8E A;  3V6E A;  1DKI A;  2DCC A;  2Y6E A;  3BBA A;  2PBH A;  2O6X A;  1QXP A;  3IOQ A;  1CPJ A;  2DC9 A;  4YYQ A;  5CVN B;  2AIM A;  5E6J A;  4X6I A;  1XKG A;  2WBF X;  4XR7 A;  3PW3 A;  1UKF A;  1PCI A;  2JQG R;  1CJL A;  1MEG A;  2Y5B A;  2E02 A;  4CDF B;  5K16 A;  3HD3 A;  2R9M A;  4QRG A;  4QRX A;  4Q8H A;  4AXL A;  1MS6 A;  2FRQ A;  1YAL A;  1NPZ A;  2YJ9 A;  3RVV A;  2P86 A;  1PPN A;  2NQA A;  2XU3 A;  2E01 A;  3BPF A;  1ZCM A;  4YYR A;  1MHW A;  4R3D A;  1NLJ A;  3E1Z B;  4CDE B;  3PBH A;  3N3K A;  3I06 A;  3KWB X;  3E9S A;  2AVW A;  1YZB A;  3GCB A;  1KHQ A;  2FQ9 A;  3RVX A;  4D8B A;  2CB5 A;  2JQF R;  2AS8 A;  1BP4 A;  4I04 A;  3DF0 A;  4P6G A;  2JRI A;  2YJ8 A;  3KW9 A;  3O1G A;  5CVM A;  3OF9 A;  1NQC A;  3QSD A;  4D8E A;  2FTD A;  5CHT A;  3ZUA A;  1NL6 A;  3TNX A;  5CHV A;  1PPO A;  3QT4 A;  2R9N A;  2AU1 A;  2BTW A;  4MSX A;  2BTW B;  2ACT A;  1YT7 A;  2FUD A;  5F02 A;  3O0U A;  2IBI A;  2FE8 A;  2FYE A;  3MHH A;  2E00 A;  1KHP A;  2P7U A;  3F75 A;  1K3B B;  4ZUX U;  1GEC E;  1EWP A;  1AYW A;  1M6D A;  3IMA A;  4IP3 A;  2NQG A;  4OEL A;  2C0Y A;  3BY4 A;  1EWM A;  3P5V A;  1CS8 A;  3N3G A;  4N79 A;  1Q6K A;  3KFQ A;  2E03 A;  2FT2 A;  4G54 A;  1CVZ A;  3CH2 X;  1QOL A;  1YVB A;  2DC6 A;  3W30 A;  4CDC B;  3H89 A;  3LFY A;  1YK8 A;  5KO3 A;  1MEM A;  4W5B A;  3BCN A;  2OP3 A;  2DJG B;  3BOW A;  1TLO A;  4YVA A;  1SP4 B;  1ATK A;  3N4C A;  2VHF A;  2DCD A;  1AU2 A;  7PCK A;  3IHP A;  9PAP A;  1QMY A;  3PNR A;  3BWK A;  4BOZ A;  2R9C A;  1ITO A;  4M0W A;  3CBJ A;  3K8U A;  1TU6 A;  3O65 A;  3IEJ A;  3QJ3 A;  2HXZ A;  2J7Q A;  3I3T A;  2FO5 A;  2DCA A;  1DEU A;  3PRM A;  1GLO A;  1AIM A;  2P0R A;  1F2B A;  1PE6 A;  3MP2 A;  2R9O A;  1ME4 A;  3PRP A;  2AUZ A;  3PT2 A;  5CVO B;  1S4V A;  1YK7 A;  4MI7 A;  1AU3 A;  3F5V A;  4XZX A;  2R9F A;  5PAD A;  4I05 A;  4YYV A;  3BPM A;  6PAD A;  3RNV A;  3V6C A;  1AEC A;  2XU1 A;  4X6J A;  1STF E;  3OVZ A;  3H6S A;  2GFO A;  1MDW A;  4PP2 E;  4Q8G A;  4OVZ A;  3KX1 A;  4A5U A;  1VSN A;  1F29 A;  3S3R A;  1GCB A;  2F1G A;  3MJ5 A;  1AU0 A;  4N4Z A;  3KKU A;  4P16 A;  2DJF B;  4YV8 A;  1KFU L;  2AUX A;  2B1M A;  3W31 A;  4IUM A;  4QRV A;  4BQV A;  4BS5 A;  2G8J A;  1U9X A;  3H8B A;  2AYN A;  4QH6 A;  2JTC A;  1TL9 A;  2H7J A;  2FRA A;  2B1N A;  3P5W A;  3OVX A;  5J94 A;  4MZS A;  4FIP A;  2HD5 A;  1F2C A;  2YJB A;  2DZY A;  3P5U A;  1PVJ A;  4WA6 A;  1BQI A;  4AXM A;  2OZ2 A;  1POP A;  4MM3 B;  1MIR A;  1Y4H A;  2CIO A;  3WXF A;  4QBB A;  1NB5 A;  4RNA A;  2G7Y A;  5JA7 A;  1PBH A;  5EGW A;  3PHW A;  3USV A;  1PPD A;  4HXD B;  3B79 A;  3D6S A;  1ME3 A;  1KXR A;  1BGO A;  3AI8 A;  3P5X A;  4OW0 A;  3BC3 A;  4PAD A;  1SNK A;  3HHA A;  2ATO A;  2DZZ A;  1CV8 A;  5EZS A;  5EZQ A;  2DOS A;  4HWY A;  4PT5 A;  2XU5 A;  3PHX A;  2DC7 A;  4P6E A;  3CBK A;  1CQD A;  3B21 A;  4GUA A;  2GHU A;  4XUI A;  1JQP A;  4REZ A;  3MHS A;  4BS6 A;  5JZE A;  3ZNH A;  4W4U A;  1EWL A;  4KLB A;  2OUL A;  1X9Y A;  3MOR A;  3CH3 X;  1DF0 A;  3IUT A;  3K24 A;  1GMY A;  3MTV A;  2R6N A;  2F7D A;  1Y08 A;  2HWK A;  3PDF A;  2AGA A;  2BDZ A;  4FJC A;  1AYV A;  2PAD A;  1F2A A;  4BOP A;  2DC8 A;  4X6H A; 
#chains in the Genus database with same CATH homology
 4PI3 A;  4CDD B;  4PP1 A;  1NB3 A;  3OIS A;  5EF4 A;  5FPW A;  4OEM A;  4DMY A;  3C9E A;  5A24 A;  3WXG A;  4RY2 A;  1U9V A;  3LTW A;  1ZIV A;  1VJV A;  2VHS A;  1PAD A;  4YYS A;  3S3Q A;  2NQD B;  2IPP B;  3H7D A;  2XU4 A;  2HH5 A;  1IWD A;  1A6R A;  4W5C A;  1CTE A;  1FH0 A;  3H8C A;  1O0E A;  4GUZ A;  2BDL A;  3M99 A;  3WXE A;  1QDQ A;  3MTN A;  1ICF A;  4YYU A;  2DCB A;  3K9M A;  4BSQ A;  1THE A;  3NHE A;  4K7C A;  2G6D A;  3ERV A;  2NQI A;  1EWO A;  4MZO A;  4DMX A;  1CSB B;  3HHI A;  3RVW A;  2VFB A;  2AYO A;  3OF8 A;  1U5I A;  4FK5 A;  1AU4 A;  3HWN A;  1EF7 A;  1PIP A;  2YJ2 A;  3LXS A;  1KFX L;  4BPV A;  2HHN A;  1HUC B;  5JH3 A;  4YYW A;  4CZW A;  3KSE A;  1AYU A;  2YJC A;  1CB5 A;  1U9Q X;  1W6F A;  2G8E A;  4N8W A;  1U9W A;  3IV2 A;  3KWZ A;  8PCH A;  2PNS A;  2PRE A;  1PXV A;  2ARY A;  1BY8 A;  1PPP A;  4I07 A;  3U8E A;  3V6E A;  2DCC A;  2Y6E A;  2PBH A;  2O6X A;  1QXP A;  3IOQ A;  1W4T A;  1CPJ A;  2DC9 A;  4YYQ A;  5CVN B;  2AIM A;  4X6I A;  1XKG A;  2WBF X;  4XR7 A;  3PW3 A;  1PCI A;  2JQG R;  1CJL A;  1GX3 A;  1MEG A;  2Y5B A;  2E02 A;  4CDF B;  4BGF A;  5K16 A;  3HD3 A;  2R9M A;  4QRG A;  4QRX A;  4Q8H A;  4AXL A;  1MS6 A;  2FRQ A;  1YAL A;  1NPZ A;  2YJ9 A;  3RVV A;  2P86 A;  1PPN A;  2NQA A;  2XU3 A;  2E01 A;  3BPF A;  1ZCM A;  4YYR A;  1MHW A;  1NLJ A;  3E1Z B;  4CDE B;  3PBH A;  3N3K A;  3I06 A;  3KWB X;  2AVW A;  3GCB A;  1KHQ A;  2FQ9 A;  3RVX A;  2CB5 A;  2JQF R;  2AS8 A;  1BP4 A;  4I04 A;  3DF0 A;  4P6G A;  2YJ8 A;  3KW9 A;  3O1G A;  5CVM A;  3OF9 A;  1NQC A;  3QSD A;  2FTD A;  5CHT A;  3ZUA A;  1NL6 A;  3TNX A;  5CHV A;  1PPO A;  3QT4 A;  2R9N A;  2AU1 A;  4MSX A;  1E2T A;  2ACT A;  1YT7 A;  2FUD A;  4B55 A;  5F02 A;  3O0U A;  2IBI A;  2FYE A;  3MHH A;  2E00 A;  1W5R A;  1KHP A;  2P7U A;  3F75 A;  1K3B B;  2BSZ A;  4ZUX U;  1GEC E;  1EWP A;  1AYW A;  1M6D A;  3IMA A;  2NQG A;  4OEL A;  2C0Y A;  1EWM A;  3P5V A;  1CS8 A;  3N3G A;  4N79 A;  1Q6K A;  3KFQ A;  2E03 A;  2FT2 A;  4G54 A;  1CVZ A;  3CH2 X;  1QOL A;  1YVB A;  4C5P A;  2DC6 A;  4CDC B;  3H89 A;  3LFY A;  1YK8 A;  1MEM A;  4W5B A;  3BCN A;  2OP3 A;  2DJG B;  3BOW A;  1TLO A;  4YVA A;  1SP4 B;  1ATK A;  3N4C A;  2VHF A;  2DCD A;  1AU2 A;  7PCK A;  3IHP A;  9PAP A;  1QMY A;  3PNR A;  3BWK A;  2R9C A;  1ITO A;  3CBJ A;  3K8U A;  1TU6 A;  3IEJ A;  3QJ3 A;  2HXZ A;  3I3T A;  2FO5 A;  2DCA A;  1DEU A;  1GLO A;  1AIM A;  2P0R A;  1F2B A;  1PE6 A;  2R9O A;  1ME4 A;  2AUZ A;  5CVO B;  4NV8 A;  1S4V A;  1YK7 A;  1AU3 A;  3F5V A;  2R9F A;  5PAD A;  4I05 A;  4YYV A;  3BPM A;  6PAD A;  3V6C A;  1AEC A;  2XU1 A;  4X6J A;  1STF E;  3OVZ A;  3H6S A;  2GFO A;  1MDW A;  4PP2 E;  4Q8G A;  3KX1 A;  1VSN A;  1F29 A;  3S3R A;  1GCB A;  2F1G A;  1AU0 A;  4N4Z A;  3KKU A;  4YV8 A;  2DJF B;  1KFU L;  2AUX A;  2B1M A;  4QRV A;  4BQV A;  4BS5 A;  2G8J A;  1U9X A;  3H8B A;  2AYN A;  4QH6 A;  1TL9 A;  2H7J A;  2FRA A;  2B1N A;  3P5W A;  3OVX A;  5J94 A;  4MZS A;  4FIP A;  2HD5 A;  1F2C A;  2YJB A;  2DZY A;  3P5U A;  4WA6 A;  1BQI A;  4AXM A;  2OZ2 A;  1POP A;  1MIR A;  1Y4H A;  2CIO A;  3WXF A;  4QBB A;  1NB5 A;  2G7Y A;  5JA7 A;  1PBH A;  5EGW A;  3USV A;  1PPD A;  3D9W A;  3B79 A;  3D6S A;  1ME3 A;  1KXR A;  1BGO A;  2VFC A;  3AI8 A;  3P5X A;  3BC3 A;  4PAD A;  4NV7 A;  1SNK A;  3HHA A;  2ATO A;  2DZZ A;  1CV8 A;  4HWY A;  2XU5 A;  2DC7 A;  4P6E A;  3CBK A;  1CQD A;  2GHU A;  4XUI A;  1JQP A;  3MHS A;  4BS6 A;  4W4U A;  1EWL A;  4KLB A;  2OUL A;  1X9Y A;  3MOR A;  3CH3 X;  1DF0 A;  3IUT A;  3K24 A;  1GMY A;  2R6N A;  2F7D A;  1Y08 A;  3PDF A;  4FJC A;  2BDZ A;  1AYV A;  2PAD A;  1F2A A;  2DC8 A;  4X6H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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