1MDWA

Crystal structure of calcium-bound protease core of calpain ii reveals the basis for intrinsic inactivation
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
323
structure length
319
Chain Sequence
ERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGFKELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDSWLLAAIASLTLNEEILARVVPLDQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGCSIDITSAADSEAVTYQKLVKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDNCPSWNTVDPEVRANLTERQEDGEFWMSFSDFLRHYSRLEICNLT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Calpain silencing by a reversible intrinsic mechanism.
pubmed doi rcsb
molecule keywords Calpain II, catalytic subunit
molecule tags Hydrolase
source organism Rattus norvegicus
total genus 94
structure length 319
sequence length 323
chains with identical sequence B
ec nomenclature ec 3.4.22.53: Calpain-2.
pdb deposition date 2002-08-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1mdwA02
1ME3A 4P6GA 1POPA 1NB5A 2DZYA 3K9MA 3IMAA 1PBHA 3O0UA 2P7UA 3CBJA 2BDLA 4MSXA 4CDFB 1Q6KA 3BPFA 4YYWA 3O1GA 4QH6A 2XU5A 2DC7A 2F7DA 3LFYA 5JA7A 3H8CA 2AYOA 1KHPA 2AU1A 2HHNA 3NHEA 3WXFA 4PP2E 3PBHA 4FJCA 4OELA 2PBHA 4N8WA 1CPJA 2O6XA 1CJLA 3U8EA 1EWLA 1DEUA 2VHSA 4I07A 1XKGA 2ARYA 1SNKA 1CVZA 2P0RA 4BQVA 2B1NA 2ATOA 3K8UA 3C9EA 1F29A 3F75A 1HUCB 3H89A 1PPPA 1BQIA 1CS8A 1AU0A 4DMYA 4K7CA 1VSNA 3P5WA 3N4CA 2FO5A 2YJCA 3RVXA 1CV8A 2FT2A 1F2AA 3K24A 4ZUXU 1KFUL 1ME4A 4G54A 3OF9A 1IWDA 2PNSA 3IOQA 3KWBX 2XU1A 1QDQA 1YALA 3IHPA 2YJ8A 2YJ9A 4YV8A 1KXRA 3OISA 3WXGA 4QRVA 1ZIVA 4MZSA 3D6SA 2HXZA 3IUTA 1YT7A 4AXMA 5JH3A 1QMYA 3N3KA 3RVWA 1CQDA 3I3TA 1U9QX 1PE6A 1TU6A 2G8JA 3KWZA 2DCBA 2DC8A 1M6DA 5CHTA 1F2CA 4N4ZA 3P5UA 1AYUA 3WXEA 3BPMA 4YYQA 4XUIA 2FQ9A 3PW3A 4YYRA 2OZ2A 4QRGA 2DCDA 1TLOA 5EF4A 1EWMA 2G7YA 4CDCB 2G8EA 2DJFB 3V6EA 3E1ZB 4HWYA 3OVXA 3CH2X 5CVMA 1GMYA 4MZOA 1JQPA 1KFXL 3B79A 2H7JA 1AU4A 3MHSA 3CH3X 1YK8A 2R9MA 2R9CA 2GHUA 3I06A 5K16A 3F5VA 1PCIA 4YYUA 1PADA 2YJBA 2NQIA 1MS6A 9PAPA 1CSBB 3KW9A 1MEMA 1QOLA 4PADA 1NL6A 3N3GA 2ACTA 3AI8A 1U9XA 1KHQA 3H8BA 4X6JA 3MTNA 3OVZA 3KFQA 1QXPA 3OF8A 3IEJA 2OP3A 1EF7A 2FUDA 4QRXA 3LXSA 2R9OA 1F2BA 2E02A 3BC3A 3BCNA 2Y5BA 3HD3A 4N79A 4BS6A 2R6NA 2AYNA 2BDZA 2FRAA 2JQFR 3DF0A 2P86A 4Q8GA 1AYWA 2E01A 1NB3A 1AYVA 4BPVA 1MDWA 2AUXA 1NQCA 2R9NA 5CHVA 3H6SA 1MIRA 2FRQA 4AXLA 1S4VA 2DCAA 6PADA 2VHFA 1MHWA 4W5BA 1STFE 3USVA 7PCKA 2DZZA 1PIPA 2AIMA 4CDEB 3PDFA 5PADA 1BP4A 1PPNA 1U9VA 2HD5A 1X9YA 3H7DA 1PPOA 1DF0A 4DMXA 2E03A 1NLJA 3S3QA 2DCCA 2GFOA 3HHIA 2XU3A 5EGWA 2DC6A 3BOWA 3PNRA 4PI3A 1VJVA 4X6HA 4P6EA 5FPWA 3KKUA 1GLOA 4BSQA 2DC9A 2OULA 1K3BB 5CVOB 4FK5A 3IV2A 3HHAA 1YVBA 3ERVA 3KX1A 4Q8HA 3ZUAA 2NQAA 8PCHA 1THEA 4CZWA 1TL9A 3P5XA 1PXVA 1U9WA 3V6CA 1ZCMA 2E00A 3MHHA 2IBIA 1Y4HA 2CB5A 2PREA 4KLBA 5A24A 2NQDB 1PPDA 4CDDB 4YVAA 4OEMA 4WA6A 4W4UA 4YYSA 1CTEA 4RY2A 4QBBA 3RVVA 2NQGA 2PADA 3QJ3A 1GECE 2IPPB 2C0YA 1GCBA 1U5IA 2JQGR 2FTDA 1MEGA 1SP4B 2R9FA 1FH0A 4PP1A 2B1MA 2YJ2A 4XR7A 2XU4A 3MORA 4FIPA 1AECA 4BS5A 4I05A 1O0EA 4I04A 1CB5A 1NPZA 3CBKA 1Y08A 2Y6EA 3BWKA 5F02A 1AU2A 2FYEA 3QT4A 1EWPA 5CVNB 3TNXA 1A6RA 2F1GA 3KSEA 1YK7A 2AVWA 3GCBA 3M99A 1ATKA 3S3RA 1ITOA 2WBFX 2AUZA 3P5VA 5J94A 1BY8A 2DJGB 1EWOA 3QSDA 4X6IA 1ICFA 1BGOA 2HH5A 2CIOA 3HWNA 2AS8A 4YYVA 1AU3A 4W5CA 2G6DA 1AIMA
chains in the Genus database with same CATH superfamily
1ME3A 4P6GA 1POPA 1NB5A 4P16A 2DZYA 3K9MA 3IMAA 1PBHA 3O0UA 2P7UA 3CBJA 3TRKA 2BDLA 4MSXA 4CDFB 1Q6KA 3BPFA 4YYWA 3O1GA 4QH6A 2XU5A 2DC7A 2F7DA 3LFYA 3PRMA 5JA7A 3H8CA 2AYOA 1KHPA 2AU1A 2HHNA 3BY4A 3NHEA 3WXFA 4PP2E 3PBHA 4FJCA 4OELA 2PBHA 4N8WA 1CPJA 2O6XA 1CJLA 3U8EA 1EWLA 1DEUA 2VHSA 4I07A 1XKGA 2ARYA 2J7QA 1SNKA 5E6JA 1CVZA 2P0RA 4BQVA 2B1NA 2ATOA 3K8UA 3C9EA 1F29A 3F75A 1HUCB 3H89A 3BBAA 1PPPA 5KO3A 3PHXA 1BQIA 1CS8A 1AU0A 4DMYA 5JZEA 4K7CA 1VSNA 3P5WA 3N4CA 2FO5A 2YJCA 3RVXA 1CV8A 2FT2A 1F2AA 3K24A 4ZUXU 1DKIA 1KFUL 1ME4A 4G54A 3OF9A 1IWDA 2PNSA 3IOQA 3KWBX 2XU1A 1QDQA 1YALA 3IHPA 2YJ8A 2YJ9A 4YV8A 1KXRA 3MP2A 3OISA 3WXGA 4QRVA 4MM3B 1ZIVA 4MZSA 3D6SA 2HXZA 3IUTA 1YT7A 4AXMA 5EZSA 5JH3A 4GUAA 3N3KA 1QMYA 3RVWA 1CQDA 3I3TA 4RKXA 1U9QX 1PE6A 1TU6A 2G8JA 4D8IA 3KWZA 2HWKA 2DCBA 2DC8A 1M6DA 4R3DA 5CHTA 1F2CA 4N4ZA 3P5UA 1AYUA 3WXEA 4RF0A 3BPMA 4YYQA 4IP3A 4XUIA 2FQ9A 3PW3A 4YYRA 2OZ2A 4QRGA 2DCDA 1TLOA 4M0WA 4RF1A 5EF4A 1EWMA 2G7YA 4CDCB 2G8EA 2DJFB 2UZJA 3V6EA 3E1ZB 4HWYA 3OVXA 3CH2X 5CVMA 1GMYA 4MZOA 1JQPA 1KFXL 3B79A 2H7JA 1PVJA 3O65A 1AU4A 3MHSA 4A5UA 3CH3X 1YK8A 2R9MA 2R9CA 3OQCA 2GHUA 3I06A 5K16A 3F5VA 1PCIA 4YYUA 1PADA 2YJBA 2NQIA 1MS6A 4REZA 9PAPA 1CSBB 3KW9A 1UKFA 1MEMA 1QOLA 4PADA 1NL6A 3N3GA 2ACTA 3AI8A 1U9XA 1KHQA 3H8BA 4X6JA 3MTNA 3OVZA 3KFQA 3W30A 1QXPA 2JRIA 3OF8A 4MI7A 3IEJA 2BTWA 2OP3A 1EF7A 2FUDA 4QRXA 3LXSA 2R9OA 1F2BA 4HXDB 2E02A 3B21A 3BC3A 3BCNA 2Y5BA 3HD3A 4N79A 4BS6A 1YZBA 2FE8A 2R6NA 2AYNA 2BDZA 2FRAA 2JQFR 3DF0A 2P86A 4Q8GA 4D8BA 1AYWA 2E01A 1NB3A 1AYVA 4BPVA 1MDWA 4BOQA 2AUXA 1NQCA 2R9NA 5CHVA 3H6SA 1MIRA 2FRQA 4AXLA 1S4VA 4BOUA 2DCAA 6PADA 2VHFA 1MHWA 4W5BA 4BOPA 1STFE 3USVA 5EZQA 2JTCA 2DZZA 7PCKA 1PIPA 4ZTBA 4RNAA 2AIMA 4CDEB 3PDFA 5PADA 1BP4A 1PPNA 1U9VA 2HD5A 1X9YA 2Z84A 3H7DA 1PPOA 1DF0A 4DMXA 2E03A 1NLJA 4IUMA 3S3QA 2DCCA 2GFOA 3HHIA 3PHWA 2XU3A 5EGWA 2DC6A 3BOWA 3PNRA 4PI3A 1VJVA 4X6HA 4P6EA 5FPWA 3BB7A 3KKUA 1GLOA 4BSQA 2DC9A 2BTWB 2OULA 1K3BB 5CVOB 4FK5A 4BOZA 3IV2A 3HHAA 4OVZA 1YVBA 3ERVA 3KX1A 4Q8HA 3ZNHA 3ZUAA 2NQAA 8PCHA 1THEA 2DOSA 4CZWA 1TL9A 3P5XA 1PXVA 1U9WA 3V6CA 3TMPA 1ZCMA 2E00A 4XZXA 3MHHA 2IBIA 1Y4HA 2CB5A 2PREA 4KLBA 5A24A 2NQDB 3PRPA 3RNVA 1PPDA 4CDDB 4YVAA 4OEMA 3C0RA 4WA6A 4W4UA 4YYSA 1CTEA 4RY2A 4QBBA 3RVVA 2NQGA 2PADA 3PT2A 3QJ3A 4WURA 1GECE 3PSEA 2IPPB 2C0YA 4OW0A 1GCBA 1U5IA 2JQGR 2FTDA 2BU3A 3W31A 1MEGA 1SP4B 2AGAA 3MTVA 2R9FA 1FH0A 4PP1A 2B1MA 2YJ2A 4XR7A 2XU4A 3MORA 4FIPA 3E9SA 1AECA 4BS5A 4I05A 1O0EA 4I04A 1CB5A 1NPZA 3CBKA 1Y08A 2Y6EA 4D8EA 3MJ5A 3BWKA 4OVZB 5F02A 1AU2A 2FYEA 3QT4A 1EWPA 5CVNB 3TNXA 1A6RA 2F1GA 3KSEA 1YK7A 4BOSA 2AVWA 3GCBA 3M99A 1ATKA 3S3RA 1ITOA 2WBFX 3P5VA 2AUZA 4PT5A 1BY8A 5J94A 2DJGB 1EWOA 3QSDA 4X6IA 1ICFA 3IFUA 3PHUA 2J7QC 1BGOA 2HH5A 2CIOA 3HWNA 2AS8A 4YYVA 1AU3A 4W5CA 2G6DA 1AIMA
chains in the Genus database with same CATH topology
1ME3A 4P6GA 1POPA 1NB5A 2DZYA 3K9MA 3IMAA 1PBHA 3O0UA 2P7UA 3CBJA 2BDLA 4MSXA 4CDFB 1Q6KA 3BPFA 4YYWA 3O1GA 4QH6A 2XU5A 2DC7A 2F7DA 3LFYA 5JA7A 3H8CA 2AYOA 1KHPA 2AU1A 2HHNA 3NHEA 3WXFA 4PP2E 3PBHA 4FJCA 4OELA 2PBHA 4N8WA 4B55A 1CPJA 2O6XA 1CJLA 3U8EA 1EWLA 1DEUA 2VHSA 4I07A 1XKGA 2ARYA 1SNKA 1CVZA 2P0RA 4BQVA 2B1NA 2ATOA 1W6FA 3K8UA 3C9EA 1F29A 3F75A 1HUCB 3H89A 1PPPA 1BQIA 1CS8A 1AU0A 4DMYA 4K7CA 1VSNA 3P5WA 3N4CA 2FO5A 2YJCA 3RVXA 4C5PA 2VFBA 1CV8A 2FT2A 1F2AA 3K24A 4ZUXU 1KFUL 1ME4A 4G54A 3OF9A 1IWDA 2PNSA 4BGFA 3IOQA 3KWBX 2XU1A 1QDQA 1YALA 3IHPA 2YJ8A 2YJ9A 4YV8A 1KXRA 2BSZA 3OISA 3WXGA 4QRVA 1ZIVA 4MZSA 3D6SA 2HXZA 3IUTA 1YT7A 4AXMA 5JH3A 1QMYA 3N3KA 3RVWA 1CQDA 3I3TA 1U9QX 1PE6A 1TU6A 2G8JA 3KWZA 2DCBA 2DC8A 1M6DA 5CHTA 1F2CA 4N4ZA 3P5UA 1AYUA 3WXEA 3BPMA 4YYQA 3LTWA 4XUIA 2FQ9A 3PW3A 4YYRA 2OZ2A 4QRGA 2DCDA 1TLOA 5EF4A 1EWMA 2G7YA 4CDCB 2G8EA 2DJFB 3V6EA 3D9WA 3E1ZB 4HWYA 3OVXA 3CH2X 5CVMA 1GMYA 4MZOA 1JQPA 1KFXL 3B79A 2H7JA 1AU4A 3MHSA 3CH3X 1YK8A 2R9MA 2R9CA 2GHUA 3I06A 5K16A 3F5VA 1PCIA 4YYUA 1PADA 2YJBA 2NQIA 1MS6A 9PAPA 1CSBB 3KW9A 1MEMA 1QOLA 4PADA 1NL6A 3N3GA 2ACTA 3AI8A 1U9XA 1KHQA 3H8BA 4X6JA 3MTNA 3OVZA 3KFQA 1QXPA 3OF8A 3IEJA 2OP3A 1EF7A 2FUDA 4QRXA 3LXSA 2R9OA 1F2BA 2E02A 3BC3A 3BCNA 2Y5BA 3HD3A 4N79A 4BS6A 4NV7A 2R6NA 2AYNA 2BDZA 2FRAA 2JQFR 3DF0A 2P86A 4Q8GA 1AYWA 2E01A 1NB3A 1AYVA 4BPVA 1MDWA 2AUXA 1NQCA 2R9NA 5CHVA 3H6SA 1GX3A 1MIRA 2FRQA 4AXLA 1S4VA 2DCAA 6PADA 2VHFA 1MHWA 4W5BA 1STFE 3USVA 7PCKA 2DZZA 1PIPA 2AIMA 4CDEB 3PDFA 5PADA 1BP4A 1PPNA 1U9VA 2HD5A 1X9YA 3H7DA 1PPOA 1DF0A 4DMXA 2E03A 1NLJA 3S3QA 2DCCA 2GFOA 3HHIA 2XU3A 5EGWA 2DC6A 3BOWA 3PNRA 4PI3A 1VJVA 4X6HA 4P6EA 5FPWA 3KKUA 1GLOA 4BSQA 2DC9A 2OULA 1K3BB 5CVOB 4FK5A 4GUZA 3IV2A 3HHAA 1YVBA 3ERVA 3KX1A 4Q8HA 3ZUAA 2NQAA 8PCHA 1THEA 4CZWA 1TL9A 1W4TA 3P5XA 1PXVA 1U9WA 3V6CA 1ZCMA 4NV8A 2E00A 3MHHA 1E2TA 2IBIA 1Y4HA 2CB5A 2PREA 4KLBA 5A24A 2NQDB 1PPDA 4CDDB 4YVAA 4OEMA 4WA6A 4W4UA 4YYSA 1CTEA 4RY2A 4QBBA 3RVVA 2NQGA 2PADA 3QJ3A 1GECE 2IPPB 2C0YA 1GCBA 1U5IA 1W5RA 2JQGR 2FTDA 1MEGA 1SP4B 2R9FA 1FH0A 4PP1A 2B1MA 2YJ2A 4XR7A 2XU4A 3MORA 4FIPA 1AECA 4BS5A 4I05A 1O0EA 2VFCA 4I04A 1CB5A 1NPZA 3CBKA 1Y08A 2Y6EA 3BWKA 5F02A 1AU2A 2FYEA 3QT4A 1EWPA 5CVNB 3TNXA 1A6RA 2F1GA 3KSEA 1YK7A 2AVWA 3GCBA 3M99A 1ATKA 3S3RA 1ITOA 2WBFX 3P5VA 2AUZA 5J94A 1BY8A 2DJGB 1EWOA 3QSDA 4X6IA 1ICFA 1BGOA 2HH5A 2CIOA 3HWNA 2AS8A 4YYVA 1AU3A 4W5CA 2G6DA 1AIMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ME3 A;  4P6G A;  1POP A;  1NB5 A;  2DZY A;  3K9M A;  3IMA A;  1PBH A;  3O0U A;  2P7U A;  3CBJ A;  2BDL A;  4MSX A;  4CDF B;  1Q6K A;  3BPF A;  4YYW A;  3O1G A;  4QH6 A;  2XU5 A;  2DC7 A;  2F7D A;  3LFY A;  5JA7 A;  3H8C A;  2AYO A;  1KHP A;  2AU1 A;  2HHN A;  3NHE A;  3WXF A;  4PP2 E;  3PBH A;  4FJC A;  4OEL A;  2PBH A;  4N8W A;  1CPJ A;  2O6X A;  1CJL A;  3U8E A;  1EWL A;  1DEU A;  2VHS A;  4I07 A;  1XKG A;  2ARY A;  1SNK A;  1CVZ A;  2P0R A;  4BQV A;  2B1N A;  2ATO A;  3K8U A;  3C9E A;  1F29 A;  3F75 A;  1HUC B;  3H89 A;  1PPP A;  1BQI A;  1CS8 A;  1AU0 A;  4DMY A;  4K7C A;  1VSN A;  3P5W A;  3N4C A;  2FO5 A;  2YJC A;  3RVX A;  1CV8 A;  2FT2 A;  1F2A A;  3K24 A;  4ZUX U;  1KFU L;  1ME4 A;  4G54 A;  3OF9 A;  1IWD A;  2PNS A;  3IOQ A;  3KWB X;  2XU1 A;  1QDQ A;  1YAL A;  3IHP A;  2YJ8 A;  2YJ9 A;  4YV8 A;  1KXR A;  3OIS A;  3WXG A;  4QRV A;  1ZIV A;  4MZS A;  3D6S A;  2HXZ A;  3IUT A;  1YT7 A;  4AXM A;  5JH3 A;  1QMY A;  3N3K A;  3RVW A;  1CQD A;  3I3T A;  1U9Q X;  1PE6 A;  1TU6 A;  2G8J A;  3KWZ A;  2DCB A;  2DC8 A;  1M6D A;  5CHT A;  1F2C A;  4N4Z A;  3P5U A;  1AYU A;  3WXE A;  3BPM A;  4YYQ A;  4XUI A;  2FQ9 A;  3PW3 A;  4YYR A;  2OZ2 A;  4QRG A;  2DCD A;  1TLO A;  5EF4 A;  1EWM A;  2G7Y A;  4CDC B;  2G8E A;  2DJF B;  3V6E A;  3E1Z B;  4HWY A;  3OVX A;  3CH2 X;  5CVM A;  1GMY A;  4MZO A;  1JQP A;  1KFX L;  3B79 A;  2H7J A;  1AU4 A;  3MHS A;  3CH3 X;  1YK8 A;  2R9M A;  2R9C A;  2GHU A;  3I06 A;  5K16 A;  3F5V A;  1PCI A;  4YYU A;  1PAD A;  2YJB A;  2NQI A;  1MS6 A;  9PAP A;  1CSB B;  3KW9 A;  1MEM A;  1QOL A;  4PAD A;  1NL6 A;  3N3G A;  2ACT A;  3AI8 A;  1U9X A;  1KHQ A;  3H8B A;  4X6J A;  3MTN A;  3OVZ A;  3KFQ A;  1QXP A;  3OF8 A;  3IEJ A;  2OP3 A;  1EF7 A;  2FUD A;  4QRX A;  3LXS A;  2R9O A;  1F2B A;  2E02 A;  3BC3 A;  3BCN A;  2Y5B A;  3HD3 A;  4N79 A;  4BS6 A;  2R6N A;  2AYN A;  2BDZ A;  2FRA A;  2JQF R;  3DF0 A;  2P86 A;  4Q8G A;  1AYW A;  2E01 A;  1NB3 A;  1AYV A;  4BPV A;  1MDW A;  2AUX A;  1NQC A;  2R9N A;  5CHV A;  3H6S A;  1MIR A;  2FRQ A;  4AXL A;  1S4V A;  2DCA A;  6PAD A;  2VHF A;  1MHW A;  4W5B A;  1STF E;  3USV A;  7PCK A;  2DZZ A;  1PIP A;  2AIM A;  4CDE B;  3PDF A;  5PAD A;  1BP4 A;  1PPN A;  1U9V A;  2HD5 A;  1X9Y A;  3H7D A;  1PPO A;  1DF0 A;  4DMX A;  2E03 A;  1NLJ A;  3S3Q A;  2DCC A;  2GFO A;  3HHI A;  2XU3 A;  5EGW A;  2DC6 A;  3BOW A;  3PNR A;  4PI3 A;  1VJV A;  4X6H A;  4P6E A;  5FPW A;  3KKU A;  1GLO A;  4BSQ A;  2DC9 A;  2OUL A;  1K3B B;  5CVO B;  4FK5 A;  3IV2 A;  3HHA A;  1YVB A;  3ERV A;  3KX1 A;  4Q8H A;  3ZUA A;  2NQA A;  8PCH A;  1THE A;  4CZW A;  1TL9 A;  3P5X A;  1PXV A;  1U9W A;  3V6C A;  1ZCM A;  2E00 A;  3MHH A;  2IBI A;  1Y4H A;  2CB5 A;  2PRE A;  4KLB A;  5A24 A;  2NQD B;  1PPD A;  4CDD B;  4YVA A;  4OEM A;  4WA6 A;  4W4U A;  4YYS A;  1CTE A;  4RY2 A;  4QBB A;  3RVV A;  2NQG A;  2PAD A;  3QJ3 A;  1GEC E;  2IPP B;  2C0Y A;  1GCB A;  1U5I A;  2JQG R;  2FTD A;  1MEG A;  1SP4 B;  2R9F A;  1FH0 A;  4PP1 A;  2B1M A;  2YJ2 A;  4XR7 A;  2XU4 A;  3MOR A;  4FIP A;  1AEC A;  4BS5 A;  4I05 A;  1O0E A;  4I04 A;  1CB5 A;  1NPZ A;  3CBK A;  1Y08 A;  2Y6E A;  3BWK A;  5F02 A;  1AU2 A;  2FYE A;  3QT4 A;  1EWP A;  5CVN B;  3TNX A;  1A6R A;  2F1G A;  3KSE A;  1YK7 A;  2AVW A;  3GCB A;  3M99 A;  1ATK A;  3S3R A;  1ITO A;  2WBF X;  2AUZ A;  3P5V A;  5J94 A;  1BY8 A;  2DJG B;  1EWO A;  3QSD A;  4X6I A;  1ICF A;  1BGO A;  2HH5 A;  2CIO A;  3HWN A;  2AS8 A;  4YYV A;  1AU3 A;  4W5C A;  2G6D A;  1AIM A; 
#chains in the Genus database with same CATH topology
 1ME3 A;  4P6G A;  1POP A;  1NB5 A;  4P16 A;  2DZY A;  3K9M A;  3IMA A;  1PBH A;  3O0U A;  2P7U A;  3CBJ A;  3TRK A;  2BDL A;  4MSX A;  4CDF B;  1Q6K A;  3BPF A;  4YYW A;  3O1G A;  4QH6 A;  2XU5 A;  2DC7 A;  2F7D A;  3LFY A;  3PRM A;  5JA7 A;  3H8C A;  2AYO A;  1KHP A;  2AU1 A;  2HHN A;  3BY4 A;  3NHE A;  3WXF A;  4PP2 E;  3PBH A;  4FJC A;  4OEL A;  2PBH A;  4N8W A;  1CPJ A;  2O6X A;  1CJL A;  3U8E A;  1EWL A;  1DEU A;  2VHS A;  4I07 A;  1XKG A;  2ARY A;  2J7Q A;  1SNK A;  5E6J A;  1CVZ A;  2P0R A;  4BQV A;  2B1N A;  2ATO A;  3K8U A;  3C9E A;  1F29 A;  3F75 A;  1HUC B;  3H89 A;  3BBA A;  1PPP A;  5KO3 A;  3PHX A;  1BQI A;  1CS8 A;  1AU0 A;  4DMY A;  5JZE A;  4K7C A;  1VSN A;  3P5W A;  3N4C A;  2FO5 A;  2YJC A;  3RVX A;  1CV8 A;  2FT2 A;  1F2A A;  3K24 A;  4ZUX U;  1DKI A;  1KFU L;  1ME4 A;  4G54 A;  3OF9 A;  1IWD A;  2PNS A;  3IOQ A;  3KWB X;  2XU1 A;  1QDQ A;  1YAL A;  3IHP A;  2YJ8 A;  2YJ9 A;  4YV8 A;  1KXR A;  3MP2 A;  3OIS A;  3WXG A;  4QRV A;  4MM3 B;  1ZIV A;  4MZS A;  3D6S A;  2HXZ A;  3IUT A;  1YT7 A;  4AXM A;  5EZS A;  5JH3 A;  4GUA A;  3N3K A;  1QMY A;  3RVW A;  1CQD A;  3I3T A;  4RKX A;  1U9Q X;  1PE6 A;  1TU6 A;  2G8J A;  4D8I A;  3KWZ A;  2HWK A;  2DCB A;  2DC8 A;  1M6D A;  4R3D A;  5CHT A;  1F2C A;  4N4Z A;  3P5U A;  1AYU A;  3WXE A;  4RF0 A;  3BPM A;  4YYQ A;  4IP3 A;  4XUI A;  2FQ9 A;  3PW3 A;  4YYR A;  2OZ2 A;  4QRG A;  2DCD A;  1TLO A;  4M0W A;  4RF1 A;  5EF4 A;  1EWM A;  2G7Y A;  4CDC B;  2G8E A;  2DJF B;  2UZJ A;  3V6E A;  3E1Z B;  4HWY A;  3OVX A;  3CH2 X;  5CVM A;  1GMY A;  4MZO A;  1JQP A;  1KFX L;  3B79 A;  2H7J A;  1PVJ A;  3O65 A;  1AU4 A;  3MHS A;  4A5U A;  3CH3 X;  1YK8 A;  2R9M A;  2R9C A;  3OQC A;  2GHU A;  3I06 A;  5K16 A;  3F5V A;  1PCI A;  4YYU A;  1PAD A;  2YJB A;  2NQI A;  1MS6 A;  4REZ A;  9PAP A;  1CSB B;  3KW9 A;  1UKF A;  1MEM A;  1QOL A;  4PAD A;  1NL6 A;  3N3G A;  2ACT A;  3AI8 A;  1U9X A;  1KHQ A;  3H8B A;  4X6J A;  3MTN A;  3OVZ A;  3KFQ A;  3W30 A;  1QXP A;  2JRI A;  3OF8 A;  4MI7 A;  3IEJ A;  2BTW A;  2OP3 A;  1EF7 A;  2FUD A;  4QRX A;  3LXS A;  2R9O A;  1F2B A;  4HXD B;  2E02 A;  3B21 A;  3BC3 A;  3BCN A;  2Y5B A;  3HD3 A;  4N79 A;  4BS6 A;  1YZB A;  2FE8 A;  2R6N A;  2AYN A;  2BDZ A;  2FRA A;  2JQF R;  3DF0 A;  2P86 A;  4Q8G A;  4D8B A;  1AYW A;  2E01 A;  1NB3 A;  1AYV A;  4BPV A;  1MDW A;  4BOQ A;  2AUX A;  1NQC A;  2R9N A;  5CHV A;  3H6S A;  1MIR A;  2FRQ A;  4AXL A;  1S4V A;  4BOU A;  2DCA A;  6PAD A;  2VHF A;  1MHW A;  4W5B A;  4BOP A;  1STF E;  3USV A;  5EZQ A;  2JTC A;  2DZZ A;  7PCK A;  1PIP A;  4ZTB A;  4RNA A;  2AIM A;  4CDE B;  3PDF A;  5PAD A;  1BP4 A;  1PPN A;  1U9V A;  2HD5 A;  1X9Y A;  2Z84 A;  3H7D A;  1PPO A;  1DF0 A;  4DMX A;  2E03 A;  1NLJ A;  4IUM A;  3S3Q A;  2DCC A;  2GFO A;  3HHI A;  3PHW A;  2XU3 A;  5EGW A;  2DC6 A;  3BOW A;  3PNR A;  4PI3 A;  1VJV A;  4X6H A;  4P6E A;  5FPW A;  3BB7 A;  3KKU A;  1GLO A;  4BSQ A;  2DC9 A;  2BTW B;  2OUL A;  1K3B B;  5CVO B;  4FK5 A;  4BOZ A;  3IV2 A;  3HHA A;  4OVZ A;  1YVB A;  3ERV A;  3KX1 A;  4Q8H A;  3ZNH A;  3ZUA A;  2NQA A;  8PCH A;  1THE A;  2DOS A;  4CZW A;  1TL9 A;  3P5X A;  1PXV A;  1U9W A;  3V6C A;  3TMP A;  1ZCM A;  2E00 A;  4XZX A;  3MHH A;  2IBI A;  1Y4H A;  2CB5 A;  2PRE A;  4KLB A;  5A24 A;  2NQD B;  3PRP A;  3RNV A;  1PPD A;  4CDD B;  4YVA A;  4OEM A;  3C0R A;  4WA6 A;  4W4U A;  4YYS A;  1CTE A;  4RY2 A;  4QBB A;  3RVV A;  2NQG A;  2PAD A;  3PT2 A;  3QJ3 A;  4WUR A;  1GEC E;  3PSE A;  2IPP B;  2C0Y A;  4OW0 A;  1GCB A;  1U5I A;  2JQG R;  2FTD A;  2BU3 A;  3W31 A;  1MEG A;  1SP4 B;  2AGA A;  3MTV A;  2R9F A;  1FH0 A;  4PP1 A;  2B1M A;  2YJ2 A;  4XR7 A;  2XU4 A;  3MOR A;  4FIP A;  3E9S A;  1AEC A;  4BS5 A;  4I05 A;  1O0E A;  4I04 A;  1CB5 A;  1NPZ A;  3CBK A;  1Y08 A;  2Y6E A;  4D8E A;  3MJ5 A;  3BWK A;  4OVZ B;  5F02 A;  1AU2 A;  2FYE A;  3QT4 A;  1EWP A;  5CVN B;  3TNX A;  1A6R A;  2F1G A;  3KSE A;  1YK7 A;  4BOS A;  2AVW A;  3GCB A;  3M99 A;  1ATK A;  3S3R A;  1ITO A;  2WBF X;  3P5V A;  2AUZ A;  4PT5 A;  1BY8 A;  5J94 A;  2DJG B;  1EWO A;  3QSD A;  4X6I A;  1ICF A;  3IFU A;  3PHU A;  2J7Q C;  1BGO A;  2HH5 A;  2CIO A;  3HWN A;  2AS8 A;  4YYV A;  1AU3 A;  4W5C A;  2G6D A;  1AIM A; 
#chains in the Genus database with same CATH homology
 1ME3 A;  4P6G A;  1POP A;  1NB5 A;  2DZY A;  3K9M A;  3IMA A;  1PBH A;  3O0U A;  2P7U A;  3CBJ A;  2BDL A;  4MSX A;  4CDF B;  1Q6K A;  3BPF A;  4YYW A;  3O1G A;  4QH6 A;  2XU5 A;  2DC7 A;  2F7D A;  3LFY A;  5JA7 A;  3H8C A;  2AYO A;  1KHP A;  2AU1 A;  2HHN A;  3NHE A;  3WXF A;  4PP2 E;  3PBH A;  4FJC A;  4OEL A;  2PBH A;  4N8W A;  4B55 A;  1CPJ A;  2O6X A;  1CJL A;  3U8E A;  1EWL A;  1DEU A;  2VHS A;  4I07 A;  1XKG A;  2ARY A;  1SNK A;  1CVZ A;  2P0R A;  4BQV A;  2B1N A;  2ATO A;  1W6F A;  3K8U A;  3C9E A;  1F29 A;  3F75 A;  1HUC B;  3H89 A;  1PPP A;  1BQI A;  1CS8 A;  1AU0 A;  4DMY A;  4K7C A;  1VSN A;  3P5W A;  3N4C A;  2FO5 A;  2YJC A;  3RVX A;  4C5P A;  2VFB A;  1CV8 A;  2FT2 A;  1F2A A;  3K24 A;  4ZUX U;  1KFU L;  1ME4 A;  4G54 A;  3OF9 A;  1IWD A;  2PNS A;  4BGF A;  3IOQ A;  3KWB X;  2XU1 A;  1QDQ A;  1YAL A;  3IHP A;  2YJ8 A;  2YJ9 A;  4YV8 A;  1KXR A;  2BSZ A;  3OIS A;  3WXG A;  4QRV A;  1ZIV A;  4MZS A;  3D6S A;  2HXZ A;  3IUT A;  1YT7 A;  4AXM A;  5JH3 A;  1QMY A;  3N3K A;  3RVW A;  1CQD A;  3I3T A;  1U9Q X;  1PE6 A;  1TU6 A;  2G8J A;  3KWZ A;  2DCB A;  2DC8 A;  1M6D A;  5CHT A;  1F2C A;  4N4Z A;  3P5U A;  1AYU A;  3WXE A;  3BPM A;  4YYQ A;  3LTW A;  4XUI A;  2FQ9 A;  3PW3 A;  4YYR A;  2OZ2 A;  4QRG A;  2DCD A;  1TLO A;  5EF4 A;  1EWM A;  2G7Y A;  4CDC B;  2G8E A;  2DJF B;  3V6E A;  3D9W A;  3E1Z B;  4HWY A;  3OVX A;  3CH2 X;  5CVM A;  1GMY A;  4MZO A;  1JQP A;  1KFX L;  3B79 A;  2H7J A;  1AU4 A;  3MHS A;  3CH3 X;  1YK8 A;  2R9M A;  2R9C A;  2GHU A;  3I06 A;  5K16 A;  3F5V A;  1PCI A;  4YYU A;  1PAD A;  2YJB A;  2NQI A;  1MS6 A;  9PAP A;  1CSB B;  3KW9 A;  1MEM A;  1QOL A;  4PAD A;  1NL6 A;  3N3G A;  2ACT A;  3AI8 A;  1U9X A;  1KHQ A;  3H8B A;  4X6J A;  3MTN A;  3OVZ A;  3KFQ A;  1QXP A;  3OF8 A;  3IEJ A;  2OP3 A;  1EF7 A;  2FUD A;  4QRX A;  3LXS A;  2R9O A;  1F2B A;  2E02 A;  3BC3 A;  3BCN A;  2Y5B A;  3HD3 A;  4N79 A;  4BS6 A;  4NV7 A;  2R6N A;  2AYN A;  2BDZ A;  2FRA A;  2JQF R;  3DF0 A;  2P86 A;  4Q8G A;  1AYW A;  2E01 A;  1NB3 A;  1AYV A;  4BPV A;  1MDW A;  2AUX A;  1NQC A;  2R9N A;  5CHV A;  3H6S A;  1GX3 A;  1MIR A;  2FRQ A;  4AXL A;  1S4V A;  2DCA A;  6PAD A;  2VHF A;  1MHW A;  4W5B A;  1STF E;  3USV A;  7PCK A;  2DZZ A;  1PIP A;  2AIM A;  4CDE B;  3PDF A;  5PAD A;  1BP4 A;  1PPN A;  1U9V A;  2HD5 A;  1X9Y A;  3H7D A;  1PPO A;  1DF0 A;  4DMX A;  2E03 A;  1NLJ A;  3S3Q A;  2DCC A;  2GFO A;  3HHI A;  2XU3 A;  5EGW A;  2DC6 A;  3BOW A;  3PNR A;  4PI3 A;  1VJV A;  4X6H A;  4P6E A;  5FPW A;  3KKU A;  1GLO A;  4BSQ A;  2DC9 A;  2OUL A;  1K3B B;  5CVO B;  4FK5 A;  4GUZ A;  3IV2 A;  3HHA A;  1YVB A;  3ERV A;  3KX1 A;  4Q8H A;  3ZUA A;  2NQA A;  8PCH A;  1THE A;  4CZW A;  1TL9 A;  1W4T A;  3P5X A;  1PXV A;  1U9W A;  3V6C A;  1ZCM A;  4NV8 A;  2E00 A;  3MHH A;  1E2T A;  2IBI A;  1Y4H A;  2CB5 A;  2PRE A;  4KLB A;  5A24 A;  2NQD B;  1PPD A;  4CDD B;  4YVA A;  4OEM A;  4WA6 A;  4W4U A;  4YYS A;  1CTE A;  4RY2 A;  4QBB A;  3RVV A;  2NQG A;  2PAD A;  3QJ3 A;  1GEC E;  2IPP B;  2C0Y A;  1GCB A;  1U5I A;  1W5R A;  2JQG R;  2FTD A;  1MEG A;  1SP4 B;  2R9F A;  1FH0 A;  4PP1 A;  2B1M A;  2YJ2 A;  4XR7 A;  2XU4 A;  3MOR A;  4FIP A;  1AEC A;  4BS5 A;  4I05 A;  1O0E A;  2VFC A;  4I04 A;  1CB5 A;  1NPZ A;  3CBK A;  1Y08 A;  2Y6E A;  3BWK A;  5F02 A;  1AU2 A;  2FYE A;  3QT4 A;  1EWP A;  5CVN B;  3TNX A;  1A6R A;  2F1G A;  3KSE A;  1YK7 A;  2AVW A;  3GCB A;  3M99 A;  1ATK A;  3S3R A;  1ITO A;  2WBF X;  3P5V A;  2AUZ A;  5J94 A;  1BY8 A;  2DJG B;  1EWO A;  3QSD A;  4X6I A;  1ICF A;  1BGO A;  2HH5 A;  2CIO A;  3HWN A;  2AS8 A;  4YYV A;  1AU3 A;  4W5C A;  2G6D A;  1AIM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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