1MDWA

Crystal structure of calcium-bound protease core of calpain ii reveals the basis for intrinsic inactivation
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
323
structure length
319
Chain Sequence
ERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGFKELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDSWLLAAIASLTLNEEILARVVPLDQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGCSIDITSAADSEAVTYQKLVKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDNCPSWNTVDPEVRANLTERQEDGEFWMSFSDFLRHYSRLEICNLT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Calpain II, catalytic subunit
publication title Calpain silencing by a reversible intrinsic mechanism.
pubmed doi rcsb
source organism Rattus norvegicus
molecule tags Hydrolase
total genus 94
structure length 319
sequence length 323
chains with identical sequence B
ec nomenclature ec 3.4.22.53: Calpain-2.
pdb deposition date 2002-08-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1mdwA02
3HWNA 2NQAA 3DF0A 2DCDA 7PCKA 3K9MA 1YT7A 4Q8GA 2FYEA 5JA7A 1NPZA 1CV8A 2PBHA 2CB5A 4K7CA 5J94A 1EWLA 2YJ8A 1K3BB 2O6XA 4YYWA 2ARYA 3V6CA 5FPWA 4W4UA 5EF4A 1U9WA 1AU4A 2CIOA 4YYSA 1THEA 3MHHA 3PW3A 1GECE 1CS8A 4KLBA 1ZIVA 3HHAA 1U9XA 1ZCMA 4G54A 1DEUA 1YK8A 4YYRA 4AXMA 4P6EA 3LFYA 4N4ZA 2AVWA 2JQGR 1PE6A 3F75A 4CDCB 2B1MA 2E02A 2C0YA 1NB5A 2XU3A 1QXPA 1U9VA 3KFQA 1AIMA 1PIPA 4BPVA 3F5VA 4X6HA 2YJBA 2YJ9A 3USVA 2NQIA 1TLOA 3CH3X 2PADA 2XU5A 2Y5BA 3P5WA 1TU6A 4YYUA 3RVVA 1X9YA 3IOQA 4X6IA 4QBBA 1GMYA 2YJ2A 3H8BA 3CH2X 3PNRA 1AU0A 3I06A 1EWOA 3P5UA 2P0RA 3H89A 1AYVA 2B1NA 1ITOA 1AYWA 1HUCB 1MS6A 3HHIA 1CTEA 2XU4A 2GFOA 2FTDA 3K24A 2F1GA 2AU1A 1NB3A 5F02A 1NQCA 3BWKA 3KW9A 3H6SA 2P86A 2HXZA 4W5BA 4BQVA 1QDQA 4PI3A 1PPPA 2FQ9A 3OF8A 1PXVA 2ACTA 2DJFB 3O0UA 1PADA 1ME3A 3OVXA 5CHTA 1AYUA 3S3RA 1SP4B 2P7UA 4DMXA 1M6DA 2DC7A 3KWBX 3P5XA 2HH5A 3RVWA 2E01A 1S4VA 3KX1A 3IUTA 3OISA 1KFXL 1POPA 2BDLA 4I07A 4MZOA 2R9FA 1FH0A 1ME4A 1NLJA 1VSNA 1KHPA 3C9EA 1PBHA 2DC6A 1Y4HA 1F2BA 1VJVA 2AS8A 5CVMA 4QRXA 3WXEA 2Y6EA 1AU2A 2GHUA 1Y08A 3LXSA 4FK5A 2JQFR 2DCBA 4BS5A 2R9CA 1QMYA 3ZUAA 4XUIA 4YYVA 1MIRA 2R9MA 3IV2A 3M99A 9PAPA 2FUDA 1DF0A 2HHNA 1U9QX 4CDEB 3QJ3A 2AUXA 3OF9A 4FJCA 1STFE 2VHSA 3V6EA 4PADA 4N79A 2VHFA 2FRQA 1AU3A 1U5IA 3N4CA 2H7JA 2IPPB 3CBKA 4QRVA 2F7DA 2OP3A 5CVNB 2DCCA 1Q6KA 2AIMA 2E00A 3GCBA 4MZSA 5PADA 2G8JA 1GCBA 3BCNA 3H8CA 4DMYA 4YVAA 3MHSA 3QT4A 2R9NA 1BGOA 4MSXA 1BY8A 1PPDA 3S3QA 4I04A 3KSEA 3IEJA 3I3TA 2ATOA 1CSBB 2DJGB 2R9OA 3N3KA 3BC3A 2E03A 2FT2A 1EWPA 2WBFX 3AI8A 8PCHA 1PCIA 2FO5A 4BSQA 2OZ2A 2DCAA 1MDWA 1NL6A 2IBIA 2AUZA 1BP4A 1ICFA 4WA6A 2FRAA 3CBJA 1IWDA 1PPNA 3U8EA 2DC9A 3BPFA 4YYQA 1KXRA 2R6NA 3QSDA 1MEMA 1SNKA 1F2CA 1F29A 3RVXA 3ERVA 2PNSA 3KWZA 1YK7A 4BS6A 1CQDA 6PADA 3MORA 1EF7A 3IHPA 4OEMA 1QOLA 1EWMA 4RY2A 1A6RA 2AYOA 1ATKA 2DZZA 4OELA 1GLOA 4PP2E 5A24A 3D6SA 1BQIA 1CVZA 3MTNA 4AXLA 4YV8A 4CDDB 4PP1A 1YALA 2YJCA 5EGWA 3TNXA 1AECA 2DZYA 4HWYA 3WXGA 1JQPA 1KFUL 4Q8HA 4N8WA 3HD3A 1PPOA 1O0EA 3N3GA 1YVBA 3BPMA 4W5CA 3OVZA 3PDFA 4FIPA 4I05A 2XU1A 4X6JA 4QH6A 5JH3A 3NHEA 3K8UA 2BDZA 3H7DA 1CB5A 1TL9A 2OULA 3E1ZB 2NQDB 2DC8A 5CHVA 3WXFA 4P6GA 3PBHA 2PREA 4XR7A 2NQGA 4CDFB 2HD5A 1XKGA 2G8EA 1CJLA 4ZUXU 3KKUA 2G7YA 1MEGA 2G6DA 1MHWA 3B79A 3O1GA 1KHQA 3IMAA 3BOWA 5K16A 4QRGA 1CPJA 2AYNA 1F2AA 3P5VA 5CVOB 4CZWA
chains in the Genus database with same CATH superfamily
3HWNA 2NQAA 3DF0A 3PT2A 2DCDA 7PCKA 3K9MA 1YT7A 4Q8GA 2FYEA 3IFUA 5JA7A 1NPZA 1CV8A 2PBHA 2CB5A 4P16A 4K7CA 5J94A 1EWLA 2YJ8A 1K3BB 2O6XA 4YYWA 2ARYA 3V6CA 5FPWA 2J7QC 4W4UA 5EF4A 1U9WA 1AU4A 2CIOA 4BOQA 4YYSA 1THEA 3MHHA 3PW3A 1GECE 1CS8A 4KLBA 1ZIVA 3HHAA 1U9XA 4OVZA 1ZCMA 4G54A 1DEUA 1YK8A 4YYRA 3TRKA 4AXMA 3PHWA 4P6EA 2JTCA 3LFYA 4N4ZA 4R3DA 2AVWA 2JQGR 1PE6A 3F75A 4CDCB 2B1MA 2E02A 2C0YA 1NB5A 2XU3A 1QXPA 1U9VA 3KFQA 1AIMA 1PIPA 3C0RA 4BPVA 3F5VA 4X6HA 2YJBA 2YJ9A 3USVA 2NQIA 1TLOA 3ZNHA 3CH3X 2PADA 2XU5A 4MI7A 2Y5BA 3P5WA 1TU6A 4YYUA 3RVVA 1X9YA 3IOQA 3RNVA 2BTWB 4X6IA 5EZSA 4QBBA 5JZEA 1GMYA 2YJ2A 3H8BA 3CH2X 3PNRA 1AU0A 3I06A 1EWOA 3P5UA 2P0RA 3H89A 4PT5A 1AYVA 2B1NA 1ITOA 1AYWA 1HUCB 1MS6A 4D8EA 3HHIA 1CTEA 4BOUA 2XU4A 2GFOA 2FTDA 3K24A 2F1GA 2AU1A 1NB3A 5F02A 1NQCA 4RF1A 3BWKA 3KW9A 3H6SA 2P86A 4D8BA 2HXZA 4W5BA 4BQVA 1QDQA 4PI3A 1PVJA 4ZTBA 3MP2A 1PPPA 2FQ9A 3OF8A 1PXVA 2ACTA 2DJFB 3O0UA 1PADA 1ME3A 3OVXA 5CHTA 1AYUA 3S3RA 1SP4B 2P7UA 4DMXA 1M6DA 2DC7A 3KWBX 3P5XA 3O65A 2HH5A 3PRPA 4XZXA 3RVWA 2E01A 1S4VA 3KX1A 3IUTA 3OISA 1KFXL 4REZA 1POPA 2BDLA 4I07A 4MZOA 2R9FA 2BTWA 1FH0A 1ME4A 1NLJA 1VSNA 1KHPA 3C9EA 3B21A 1PBHA 2DC6A 3W30A 1Y4HA 1F2BA 1VJVA 2AS8A 5CVMA 4M0WA 4QRXA 2Z84A 3WXEA 2Y6EA 1AU2A 2GHUA 1Y08A 3LXSA 4FK5A 2JQFR 2DCBA 4BS5A 2R9CA 4RKXA 1QMYA 3ZUAA 4OW0A 3PHXA 4BOZA 4XUIA 4YYVA 1MIRA 2R9MA 3IV2A 3M99A 9PAPA 2FUDA 1DF0A 2HHNA 2AGAA 3W31A 1U9QX 4CDEB 3QJ3A 2AUXA 3OF9A 4FJCA 1STFE 2VHSA 3V6EA 4BOSA 4PADA 1UKFA 4N79A 5KO3A 2VHFA 3BBAA 2FRQA 1AU3A 1U5IA 3N4CA 3MTVA 2H7JA 2IPPB 3CBKA 4QRVA 2F7DA 2J7QA 2OP3A 5CVNB 2DCCA 1Q6KA 2AIMA 2E00A 3GCBA 4MZSA 5PADA 2G8JA 1GCBA 4A5UA 3BCNA 3H8CA 4DMYA 4YVAA 3MHSA 3QT4A 2R9NA 2UZJA 3BB7A 1BGOA 4MSXA 1BY8A 1PPDA 3S3QA 4I04A 3KSEA 3IEJA 3I3TA 2ATOA 1CSBB 2DJGB 2R9OA 3N3KA 3BC3A 2E03A 2FT2A 1EWPA 2WBFX 3AI8A 8PCHA 1PCIA 2FO5A 4BSQA 2OZ2A 2DCAA 1MDWA 1NL6A 2JRIA 2IBIA 2AUZA 1BP4A 1ICFA 4WA6A 4WURA 4HXDB 2FRAA 3CBJA 4D8IA 1IWDA 1PPNA 3U8EA 2DC9A 3BPFA 4YYQA 1KXRA 4GUAA 2R6NA 1MEMA 1SNKA 1F2CA 1F29A 2BU3A 3QSDA 3ERVA 3RVXA 2PNSA 3KWZA 3MJ5A 1YK7A 4BS6A 1CQDA 5EZQA 6PADA 3MORA 1EF7A 3E9SA 3IHPA 4OEMA 1QOLA 1EWMA 4RY2A 1A6RA 2AYOA 1ATKA 2DZZA 4OELA 1GLOA 4PP2E 5A24A 2HWKA 3D6SA 3BY4A 1BQIA 1CVZA 3MTNA 4AXLA 4YV8A 4CDDB 4PP1A 1YALA 2YJCA 5EGWA 3TMPA 1YZBA 3TNXA 1AECA 2DZYA 4HWYA 4IUMA 4MM3B 3WXGA 4BOPA 1JQPA 1KFUL 4Q8HA 4N8WA 2DOSA 3HD3A 1PPOA 1O0EA 3N3GA 1YVBA 3BPMA 4W5CA 3OVZA 3PDFA 4FIPA 4I05A 2XU1A 4X6JA 4QH6A 5JH3A 3NHEA 3K8UA 2BDZA 3H7DA 1CB5A 1TL9A 2OULA 3E1ZB 2NQDB 2DC8A 5CHVA 3WXFA 4RF0A 3PHUA 4IP3A 3PBHA 4P6GA 3PSEA 3OQCA 4OVZB 2PREA 4XR7A 2NQGA 4CDFB 2HD5A 1XKGA 2G8EA 1CJLA 5E6JA 4ZUXU 3KKUA 2G7YA 1MEGA 2G6DA 1MHWA 4RNAA 1DKIA 3B79A 3O1GA 1KHQA 3IMAA 3PRMA 3BOWA 5K16A 4QRGA 1CPJA 2AYNA 2FE8A 1F2AA 3P5VA 5CVOB 4CZWA
chains in the Genus database with same CATH topology
3HWNA 2NQAA 3DF0A 2DCDA 7PCKA 3K9MA 1YT7A 4Q8GA 2FYEA 5JA7A 1NPZA 1CV8A 2PBHA 2CB5A 4K7CA 5J94A 1EWLA 2YJ8A 1K3BB 2O6XA 4YYWA 2ARYA 3V6CA 5FPWA 4W4UA 5EF4A 1U9WA 1AU4A 2CIOA 4YYSA 1THEA 3MHHA 3PW3A 1GECE 1CS8A 4NV7A 4KLBA 1ZIVA 1W6FA 3HHAA 1U9XA 1ZCMA 4G54A 1DEUA 1YK8A 4YYRA 4AXMA 4P6EA 3LFYA 4N4ZA 2AVWA 2JQGR 1PE6A 3F75A 4CDCB 2B1MA 2E02A 2C0YA 1NB5A 2XU3A 1QXPA 1U9VA 3KFQA 1AIMA 1PIPA 4BPVA 3F5VA 4BGFA 4X6HA 2YJBA 2YJ9A 3USVA 2NQIA 1TLOA 3CH3X 2BSZA 2PADA 2XU5A 2Y5BA 3P5WA 1TU6A 4YYUA 3RVVA 1X9YA 3IOQA 4X6IA 4QBBA 1GMYA 2YJ2A 3H8BA 3CH2X 3PNRA 1AU0A 3I06A 1EWOA 1E2TA 3P5UA 2P0RA 3H89A 1AYVA 2B1NA 1ITOA 1AYWA 1HUCB 1MS6A 3HHIA 1CTEA 1GX3A 2XU4A 2GFOA 2FTDA 3K24A 2F1GA 2AU1A 1NB3A 5F02A 1NQCA 3BWKA 3KW9A 3H6SA 2P86A 2HXZA 4W5BA 4BQVA 1QDQA 4PI3A 1PPPA 2FQ9A 3OF8A 1PXVA 2ACTA 2DJFB 3O0UA 1PADA 1ME3A 3OVXA 5CHTA 1AYUA 3S3RA 1SP4B 2P7UA 4DMXA 1M6DA 2DC7A 3KWBX 3P5XA 2HH5A 3RVWA 2E01A 1S4VA 3KX1A 3IUTA 3OISA 1KFXL 1POPA 2BDLA 4I07A 4MZOA 2R9FA 1FH0A 1ME4A 1NLJA 1VSNA 1KHPA 3C9EA 1PBHA 2DC6A 1Y4HA 1F2BA 1VJVA 2AS8A 5CVMA 4QRXA 3WXEA 2Y6EA 1AU2A 2GHUA 1Y08A 3LXSA 4NV8A 4B55A 4FK5A 2JQFR 2DCBA 4BS5A 2R9CA 1QMYA 3ZUAA 4XUIA 4YYVA 2VFBA 1MIRA 2R9MA 3IV2A 3M99A 1W5RA 9PAPA 2FUDA 1DF0A 2HHNA 4C5PA 1U9QX 4CDEB 3QJ3A 2AUXA 3OF9A 4FJCA 1STFE 2VHSA 3V6EA 4PADA 4N79A 3LTWA 2VHFA 2FRQA 1AU3A 1U5IA 3N4CA 2H7JA 2IPPB 3CBKA 4QRVA 2F7DA 2OP3A 5CVNB 2DCCA 1Q6KA 2AIMA 2E00A 3GCBA 4MZSA 5PADA 2G8JA 1GCBA 3BCNA 3H8CA 4DMYA 4YVAA 3MHSA 3QT4A 2R9NA 1BGOA 4MSXA 1BY8A 1PPDA 3S3QA 4I04A 3KSEA 3IEJA 3I3TA 2ATOA 1CSBB 2DJGB 2R9OA 3N3KA 3BC3A 2E03A 2FT2A 1EWPA 2WBFX 3AI8A 8PCHA 1PCIA 2FO5A 4BSQA 2OZ2A 2DCAA 1MDWA 1NL6A 2IBIA 2AUZA 1BP4A 1ICFA 4WA6A 2FRAA 3CBJA 1IWDA 1PPNA 3U8EA 2DC9A 3BPFA 4YYQA 1KXRA 2R6NA 3QSDA 1MEMA 1SNKA 1F2CA 1F29A 3RVXA 3ERVA 2PNSA 3KWZA 1YK7A 4BS6A 1CQDA 6PADA 3MORA 1EF7A 3IHPA 4OEMA 1QOLA 1EWMA 3D9WA 4RY2A 1A6RA 2AYOA 1ATKA 2DZZA 4OELA 1GLOA 4PP2E 5A24A 3D6SA 1BQIA 1CVZA 3MTNA 4AXLA 4YV8A 4CDDB 4PP1A 1YALA 2YJCA 5EGWA 3TNXA 1AECA 2DZYA 4HWYA 3WXGA 1JQPA 1KFUL 4Q8HA 4N8WA 3HD3A 1PPOA 1O0EA 3N3GA 1YVBA 3BPMA 4W5CA 3OVZA 3PDFA 4FIPA 4I05A 1W4TA 2XU1A 4X6JA 4QH6A 5JH3A 3NHEA 3K8UA 2BDZA 3H7DA 1CB5A 1TL9A 2OULA 3E1ZB 2NQDB 2VFCA 2DC8A 5CHVA 3WXFA 3PBHA 4P6GA 2PREA 4XR7A 4GUZA 2NQGA 4CDFB 2HD5A 1XKGA 2G8EA 1CJLA 4ZUXU 3KKUA 2G7YA 1MEGA 2G6DA 1MHWA 3B79A 3O1GA 1KHQA 3IMAA 3BOWA 5K16A 4QRGA 1CPJA 2AYNA 1F2AA 3P5VA 5CVOB 4CZWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HWN A;  2NQA A;  3DF0 A;  2DCD A;  7PCK A;  3K9M A;  1YT7 A;  4Q8G A;  2FYE A;  5JA7 A;  1NPZ A;  1CV8 A;  2PBH A;  2CB5 A;  4K7C A;  5J94 A;  1EWL A;  2YJ8 A;  1K3B B;  2O6X A;  4YYW A;  2ARY A;  3V6C A;  5FPW A;  4W4U A;  5EF4 A;  1U9W A;  1AU4 A;  2CIO A;  4YYS A;  1THE A;  3MHH A;  3PW3 A;  1GEC E;  1CS8 A;  4KLB A;  1ZIV A;  3HHA A;  1U9X A;  1ZCM A;  4G54 A;  1DEU A;  1YK8 A;  4YYR A;  4AXM A;  4P6E A;  3LFY A;  4N4Z A;  2AVW A;  2JQG R;  1PE6 A;  3F75 A;  4CDC B;  2B1M A;  2E02 A;  2C0Y A;  1NB5 A;  2XU3 A;  1QXP A;  1U9V A;  3KFQ A;  1AIM A;  1PIP A;  4BPV A;  3F5V A;  4X6H A;  2YJB A;  2YJ9 A;  3USV A;  2NQI A;  1TLO A;  3CH3 X;  2PAD A;  2XU5 A;  2Y5B A;  3P5W A;  1TU6 A;  4YYU A;  3RVV A;  1X9Y A;  3IOQ A;  4X6I A;  4QBB A;  1GMY A;  2YJ2 A;  3H8B A;  3CH2 X;  3PNR A;  1AU0 A;  3I06 A;  1EWO A;  3P5U A;  2P0R A;  3H89 A;  1AYV A;  2B1N A;  1ITO A;  1AYW A;  1HUC B;  1MS6 A;  3HHI A;  1CTE A;  2XU4 A;  2GFO A;  2FTD A;  3K24 A;  2F1G A;  2AU1 A;  1NB3 A;  5F02 A;  1NQC A;  3BWK A;  3KW9 A;  3H6S A;  2P86 A;  2HXZ A;  4W5B A;  4BQV A;  1QDQ A;  4PI3 A;  1PPP A;  2FQ9 A;  3OF8 A;  1PXV A;  2ACT A;  2DJF B;  3O0U A;  1PAD A;  1ME3 A;  3OVX A;  5CHT A;  1AYU A;  3S3R A;  1SP4 B;  2P7U A;  4DMX A;  1M6D A;  2DC7 A;  3KWB X;  3P5X A;  2HH5 A;  3RVW A;  2E01 A;  1S4V A;  3KX1 A;  3IUT A;  3OIS A;  1KFX L;  1POP A;  2BDL A;  4I07 A;  4MZO A;  2R9F A;  1FH0 A;  1ME4 A;  1NLJ A;  1VSN A;  1KHP A;  3C9E A;  1PBH A;  2DC6 A;  1Y4H A;  1F2B A;  1VJV A;  2AS8 A;  5CVM A;  4QRX A;  3WXE A;  2Y6E A;  1AU2 A;  2GHU A;  1Y08 A;  3LXS A;  4FK5 A;  2JQF R;  2DCB A;  4BS5 A;  2R9C A;  1QMY A;  3ZUA A;  4XUI A;  4YYV A;  1MIR A;  2R9M A;  3IV2 A;  3M99 A;  9PAP A;  2FUD A;  1DF0 A;  2HHN A;  1U9Q X;  4CDE B;  3QJ3 A;  2AUX A;  3OF9 A;  4FJC A;  1STF E;  2VHS A;  3V6E A;  4PAD A;  4N79 A;  2VHF A;  2FRQ A;  1AU3 A;  1U5I A;  3N4C A;  2H7J A;  2IPP B;  3CBK A;  4QRV A;  2F7D A;  2OP3 A;  5CVN B;  2DCC A;  1Q6K A;  2AIM A;  2E00 A;  3GCB A;  4MZS A;  5PAD A;  2G8J A;  1GCB A;  3BCN A;  3H8C A;  4DMY A;  4YVA A;  3MHS A;  3QT4 A;  2R9N A;  1BGO A;  4MSX A;  1BY8 A;  1PPD A;  3S3Q A;  4I04 A;  3KSE A;  3IEJ A;  3I3T A;  2ATO A;  1CSB B;  2DJG B;  2R9O A;  3N3K A;  3BC3 A;  2E03 A;  2FT2 A;  1EWP A;  2WBF X;  3AI8 A;  8PCH A;  1PCI A;  2FO5 A;  4BSQ A;  2OZ2 A;  2DCA A;  1MDW A;  1NL6 A;  2IBI A;  2AUZ A;  1BP4 A;  1ICF A;  4WA6 A;  2FRA A;  3CBJ A;  1IWD A;  1PPN A;  3U8E A;  2DC9 A;  3BPF A;  4YYQ A;  1KXR A;  2R6N A;  3QSD A;  1MEM A;  1SNK A;  1F2C A;  1F29 A;  3RVX A;  3ERV A;  2PNS A;  3KWZ A;  1YK7 A;  4BS6 A;  1CQD A;  6PAD A;  3MOR A;  1EF7 A;  3IHP A;  4OEM A;  1QOL A;  1EWM A;  4RY2 A;  1A6R A;  2AYO A;  1ATK A;  2DZZ A;  4OEL A;  1GLO A;  4PP2 E;  5A24 A;  3D6S A;  1BQI A;  1CVZ A;  3MTN A;  4AXL A;  4YV8 A;  4CDD B;  4PP1 A;  1YAL A;  2YJC A;  5EGW A;  3TNX A;  1AEC A;  2DZY A;  4HWY A;  3WXG A;  1JQP A;  1KFU L;  4Q8H A;  4N8W A;  3HD3 A;  1PPO A;  1O0E A;  3N3G A;  1YVB A;  3BPM A;  4W5C A;  3OVZ A;  3PDF A;  4FIP A;  4I05 A;  2XU1 A;  4X6J A;  4QH6 A;  5JH3 A;  3NHE A;  3K8U A;  2BDZ A;  3H7D A;  1CB5 A;  1TL9 A;  2OUL A;  3E1Z B;  2NQD B;  2DC8 A;  5CHV A;  3WXF A;  4P6G A;  3PBH A;  2PRE A;  4XR7 A;  2NQG A;  4CDF B;  2HD5 A;  1XKG A;  2G8E A;  1CJL A;  4ZUX U;  3KKU A;  2G7Y A;  1MEG A;  2G6D A;  1MHW A;  3B79 A;  3O1G A;  1KHQ A;  3IMA A;  3BOW A;  5K16 A;  4QRG A;  1CPJ A;  2AYN A;  1F2A A;  3P5V A;  5CVO B;  4CZW A; 
#chains in the Genus database with same CATH topology
 3HWN A;  2NQA A;  3DF0 A;  3PT2 A;  2DCD A;  7PCK A;  3K9M A;  1YT7 A;  4Q8G A;  2FYE A;  3IFU A;  5JA7 A;  1NPZ A;  1CV8 A;  2PBH A;  2CB5 A;  4P16 A;  4K7C A;  5J94 A;  1EWL A;  2YJ8 A;  1K3B B;  2O6X A;  4YYW A;  2ARY A;  3V6C A;  5FPW A;  2J7Q C;  4W4U A;  5EF4 A;  1U9W A;  1AU4 A;  2CIO A;  4BOQ A;  4YYS A;  1THE A;  3MHH A;  3PW3 A;  1GEC E;  1CS8 A;  4KLB A;  1ZIV A;  3HHA A;  1U9X A;  4OVZ A;  1ZCM A;  4G54 A;  1DEU A;  1YK8 A;  4YYR A;  3TRK A;  4AXM A;  3PHW A;  4P6E A;  2JTC A;  3LFY A;  4N4Z A;  4R3D A;  2AVW A;  2JQG R;  1PE6 A;  3F75 A;  4CDC B;  2B1M A;  2E02 A;  2C0Y A;  1NB5 A;  2XU3 A;  1QXP A;  1U9V A;  3KFQ A;  1AIM A;  1PIP A;  3C0R A;  4BPV A;  3F5V A;  4X6H A;  2YJB A;  2YJ9 A;  3USV A;  2NQI A;  1TLO A;  3ZNH A;  3CH3 X;  2PAD A;  2XU5 A;  4MI7 A;  2Y5B A;  3P5W A;  1TU6 A;  4YYU A;  3RVV A;  1X9Y A;  3IOQ A;  3RNV A;  2BTW B;  4X6I A;  5EZS A;  4QBB A;  5JZE A;  1GMY A;  2YJ2 A;  3H8B A;  3CH2 X;  3PNR A;  1AU0 A;  3I06 A;  1EWO A;  3P5U A;  2P0R A;  3H89 A;  4PT5 A;  1AYV A;  2B1N A;  1ITO A;  1AYW A;  1HUC B;  1MS6 A;  4D8E A;  3HHI A;  1CTE A;  4BOU A;  2XU4 A;  2GFO A;  2FTD A;  3K24 A;  2F1G A;  2AU1 A;  1NB3 A;  5F02 A;  1NQC A;  4RF1 A;  3BWK A;  3KW9 A;  3H6S A;  2P86 A;  4D8B A;  2HXZ A;  4W5B A;  4BQV A;  1QDQ A;  4PI3 A;  1PVJ A;  4ZTB A;  3MP2 A;  1PPP A;  2FQ9 A;  3OF8 A;  1PXV A;  2ACT A;  2DJF B;  3O0U A;  1PAD A;  1ME3 A;  3OVX A;  5CHT A;  1AYU A;  3S3R A;  1SP4 B;  2P7U A;  4DMX A;  1M6D A;  2DC7 A;  3KWB X;  3P5X A;  3O65 A;  2HH5 A;  3PRP A;  4XZX A;  3RVW A;  2E01 A;  1S4V A;  3KX1 A;  3IUT A;  3OIS A;  1KFX L;  4REZ A;  1POP A;  2BDL A;  4I07 A;  4MZO A;  2R9F A;  2BTW A;  1FH0 A;  1ME4 A;  1NLJ A;  1VSN A;  1KHP A;  3C9E A;  3B21 A;  1PBH A;  2DC6 A;  3W30 A;  1Y4H A;  1F2B A;  1VJV A;  2AS8 A;  5CVM A;  4M0W A;  4QRX A;  2Z84 A;  3WXE A;  2Y6E A;  1AU2 A;  2GHU A;  1Y08 A;  3LXS A;  4FK5 A;  2JQF R;  2DCB A;  4BS5 A;  2R9C A;  4RKX A;  1QMY A;  3ZUA A;  4OW0 A;  3PHX A;  4BOZ A;  4XUI A;  4YYV A;  1MIR A;  2R9M A;  3IV2 A;  3M99 A;  9PAP A;  2FUD A;  1DF0 A;  2HHN A;  2AGA A;  3W31 A;  1U9Q X;  4CDE B;  3QJ3 A;  2AUX A;  3OF9 A;  4FJC A;  1STF E;  2VHS A;  3V6E A;  4BOS A;  4PAD A;  1UKF A;  4N79 A;  5KO3 A;  2VHF A;  3BBA A;  2FRQ A;  1AU3 A;  1U5I A;  3N4C A;  3MTV A;  2H7J A;  2IPP B;  3CBK A;  4QRV A;  2F7D A;  2J7Q A;  2OP3 A;  5CVN B;  2DCC A;  1Q6K A;  2AIM A;  2E00 A;  3GCB A;  4MZS A;  5PAD A;  2G8J A;  1GCB A;  4A5U A;  3BCN A;  3H8C A;  4DMY A;  4YVA A;  3MHS A;  3QT4 A;  2R9N A;  2UZJ A;  3BB7 A;  1BGO A;  4MSX A;  1BY8 A;  1PPD A;  3S3Q A;  4I04 A;  3KSE A;  3IEJ A;  3I3T A;  2ATO A;  1CSB B;  2DJG B;  2R9O A;  3N3K A;  3BC3 A;  2E03 A;  2FT2 A;  1EWP A;  2WBF X;  3AI8 A;  8PCH A;  1PCI A;  2FO5 A;  4BSQ A;  2OZ2 A;  2DCA A;  1MDW A;  1NL6 A;  2JRI A;  2IBI A;  2AUZ A;  1BP4 A;  1ICF A;  4WA6 A;  4WUR A;  4HXD B;  2FRA A;  3CBJ A;  4D8I A;  1IWD A;  1PPN A;  3U8E A;  2DC9 A;  3BPF A;  4YYQ A;  1KXR A;  4GUA A;  2R6N A;  1MEM A;  1SNK A;  1F2C A;  1F29 A;  2BU3 A;  3QSD A;  3ERV A;  3RVX A;  2PNS A;  3KWZ A;  3MJ5 A;  1YK7 A;  4BS6 A;  1CQD A;  5EZQ A;  6PAD A;  3MOR A;  1EF7 A;  3E9S A;  3IHP A;  4OEM A;  1QOL A;  1EWM A;  4RY2 A;  1A6R A;  2AYO A;  1ATK A;  2DZZ A;  4OEL A;  1GLO A;  4PP2 E;  5A24 A;  2HWK A;  3D6S A;  3BY4 A;  1BQI A;  1CVZ A;  3MTN A;  4AXL A;  4YV8 A;  4CDD B;  4PP1 A;  1YAL A;  2YJC A;  5EGW A;  3TMP A;  1YZB A;  3TNX A;  1AEC A;  2DZY A;  4HWY A;  4IUM A;  4MM3 B;  3WXG A;  4BOP A;  1JQP A;  1KFU L;  4Q8H A;  4N8W A;  2DOS A;  3HD3 A;  1PPO A;  1O0E A;  3N3G A;  1YVB A;  3BPM A;  4W5C A;  3OVZ A;  3PDF A;  4FIP A;  4I05 A;  2XU1 A;  4X6J A;  4QH6 A;  5JH3 A;  3NHE A;  3K8U A;  2BDZ A;  3H7D A;  1CB5 A;  1TL9 A;  2OUL A;  3E1Z B;  2NQD B;  2DC8 A;  5CHV A;  3WXF A;  4RF0 A;  3PHU A;  4IP3 A;  3PBH A;  4P6G A;  3PSE A;  3OQC A;  4OVZ B;  2PRE A;  4XR7 A;  2NQG A;  4CDF B;  2HD5 A;  1XKG A;  2G8E A;  1CJL A;  5E6J A;  4ZUX U;  3KKU A;  2G7Y A;  1MEG A;  2G6D A;  1MHW A;  4RNA A;  1DKI A;  3B79 A;  3O1G A;  1KHQ A;  3IMA A;  3PRM A;  3BOW A;  5K16 A;  4QRG A;  1CPJ A;  2AYN A;  2FE8 A;  1F2A A;  3P5V A;  5CVO B;  4CZW A; 
#chains in the Genus database with same CATH homology
 3HWN A;  2NQA A;  3DF0 A;  2DCD A;  7PCK A;  3K9M A;  1YT7 A;  4Q8G A;  2FYE A;  5JA7 A;  1NPZ A;  1CV8 A;  2PBH A;  2CB5 A;  4K7C A;  5J94 A;  1EWL A;  2YJ8 A;  1K3B B;  2O6X A;  4YYW A;  2ARY A;  3V6C A;  5FPW A;  4W4U A;  5EF4 A;  1U9W A;  1AU4 A;  2CIO A;  4YYS A;  1THE A;  3MHH A;  3PW3 A;  1GEC E;  1CS8 A;  4NV7 A;  4KLB A;  1ZIV A;  1W6F A;  3HHA A;  1U9X A;  1ZCM A;  4G54 A;  1DEU A;  1YK8 A;  4YYR A;  4AXM A;  4P6E A;  3LFY A;  4N4Z A;  2AVW A;  2JQG R;  1PE6 A;  3F75 A;  4CDC B;  2B1M A;  2E02 A;  2C0Y A;  1NB5 A;  2XU3 A;  1QXP A;  1U9V A;  3KFQ A;  1AIM A;  1PIP A;  4BPV A;  3F5V A;  4BGF A;  4X6H A;  2YJB A;  2YJ9 A;  3USV A;  2NQI A;  1TLO A;  3CH3 X;  2BSZ A;  2PAD A;  2XU5 A;  2Y5B A;  3P5W A;  1TU6 A;  4YYU A;  3RVV A;  1X9Y A;  3IOQ A;  4X6I A;  4QBB A;  1GMY A;  2YJ2 A;  3H8B A;  3CH2 X;  3PNR A;  1AU0 A;  3I06 A;  1EWO A;  1E2T A;  3P5U A;  2P0R A;  3H89 A;  1AYV A;  2B1N A;  1ITO A;  1AYW A;  1HUC B;  1MS6 A;  3HHI A;  1CTE A;  1GX3 A;  2XU4 A;  2GFO A;  2FTD A;  3K24 A;  2F1G A;  2AU1 A;  1NB3 A;  5F02 A;  1NQC A;  3BWK A;  3KW9 A;  3H6S A;  2P86 A;  2HXZ A;  4W5B A;  4BQV A;  1QDQ A;  4PI3 A;  1PPP A;  2FQ9 A;  3OF8 A;  1PXV A;  2ACT A;  2DJF B;  3O0U A;  1PAD A;  1ME3 A;  3OVX A;  5CHT A;  1AYU A;  3S3R A;  1SP4 B;  2P7U A;  4DMX A;  1M6D A;  2DC7 A;  3KWB X;  3P5X A;  2HH5 A;  3RVW A;  2E01 A;  1S4V A;  3KX1 A;  3IUT A;  3OIS A;  1KFX L;  1POP A;  2BDL A;  4I07 A;  4MZO A;  2R9F A;  1FH0 A;  1ME4 A;  1NLJ A;  1VSN A;  1KHP A;  3C9E A;  1PBH A;  2DC6 A;  1Y4H A;  1F2B A;  1VJV A;  2AS8 A;  5CVM A;  4QRX A;  3WXE A;  2Y6E A;  1AU2 A;  2GHU A;  1Y08 A;  3LXS A;  4NV8 A;  4B55 A;  4FK5 A;  2JQF R;  2DCB A;  4BS5 A;  2R9C A;  1QMY A;  3ZUA A;  4XUI A;  4YYV A;  2VFB A;  1MIR A;  2R9M A;  3IV2 A;  3M99 A;  1W5R A;  9PAP A;  2FUD A;  1DF0 A;  2HHN A;  4C5P A;  1U9Q X;  4CDE B;  3QJ3 A;  2AUX A;  3OF9 A;  4FJC A;  1STF E;  2VHS A;  3V6E A;  4PAD A;  4N79 A;  3LTW A;  2VHF A;  2FRQ A;  1AU3 A;  1U5I A;  3N4C A;  2H7J A;  2IPP B;  3CBK A;  4QRV A;  2F7D A;  2OP3 A;  5CVN B;  2DCC A;  1Q6K A;  2AIM A;  2E00 A;  3GCB A;  4MZS A;  5PAD A;  2G8J A;  1GCB A;  3BCN A;  3H8C A;  4DMY A;  4YVA A;  3MHS A;  3QT4 A;  2R9N A;  1BGO A;  4MSX A;  1BY8 A;  1PPD A;  3S3Q A;  4I04 A;  3KSE A;  3IEJ A;  3I3T A;  2ATO A;  1CSB B;  2DJG B;  2R9O A;  3N3K A;  3BC3 A;  2E03 A;  2FT2 A;  1EWP A;  2WBF X;  3AI8 A;  8PCH A;  1PCI A;  2FO5 A;  4BSQ A;  2OZ2 A;  2DCA A;  1MDW A;  1NL6 A;  2IBI A;  2AUZ A;  1BP4 A;  1ICF A;  4WA6 A;  2FRA A;  3CBJ A;  1IWD A;  1PPN A;  3U8E A;  2DC9 A;  3BPF A;  4YYQ A;  1KXR A;  2R6N A;  3QSD A;  1MEM A;  1SNK A;  1F2C A;  1F29 A;  3RVX A;  3ERV A;  2PNS A;  3KWZ A;  1YK7 A;  4BS6 A;  1CQD A;  6PAD A;  3MOR A;  1EF7 A;  3IHP A;  4OEM A;  1QOL A;  1EWM A;  3D9W A;  4RY2 A;  1A6R A;  2AYO A;  1ATK A;  2DZZ A;  4OEL A;  1GLO A;  4PP2 E;  5A24 A;  3D6S A;  1BQI A;  1CVZ A;  3MTN A;  4AXL A;  4YV8 A;  4CDD B;  4PP1 A;  1YAL A;  2YJC A;  5EGW A;  3TNX A;  1AEC A;  2DZY A;  4HWY A;  3WXG A;  1JQP A;  1KFU L;  4Q8H A;  4N8W A;  3HD3 A;  1PPO A;  1O0E A;  3N3G A;  1YVB A;  3BPM A;  4W5C A;  3OVZ A;  3PDF A;  4FIP A;  4I05 A;  1W4T A;  2XU1 A;  4X6J A;  4QH6 A;  5JH3 A;  3NHE A;  3K8U A;  2BDZ A;  3H7D A;  1CB5 A;  1TL9 A;  2OUL A;  3E1Z B;  2NQD B;  2VFC A;  2DC8 A;  5CHV A;  3WXF A;  3PBH A;  4P6G A;  2PRE A;  4XR7 A;  4GUZ A;  2NQG A;  4CDF B;  2HD5 A;  1XKG A;  2G8E A;  1CJL A;  4ZUX U;  3KKU A;  2G7Y A;  1MEG A;  2G6D A;  1MHW A;  3B79 A;  3O1G A;  1KHQ A;  3IMA A;  3BOW A;  5K16 A;  4QRG A;  1CPJ A;  2AYN A;  1F2A A;  3P5V A;  5CVO B;  4CZW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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