2P7UA

The crystal structure of rhodesain, the major cysteine protease of t. brucei rhodesiense, bound to inhibitor k777
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
215
structure length
215
Chain Sequence
APAAVDWREKGAVTPVKDQGQCGSCWAFSTIGNIEGQWQVAGNPLVSLSEQMLVSCDTIDFGCGGGLMDNAFNWIVNSNGGNVFTEASYPYVSGNGEQPQCQMNGHEIGAAITDHVDLPQDEDAIAAYLAENGPLAIAVDATSFMDYNGGILTSCTSEQLDHGVLLVGYNDASNPPYWIIKNSWSNMWGEDGYIRIEKGTNQCLMNQAVSSAVVG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Vinyl sulfones as antiparasitic agents and a structural basis for drug design.
pubmed doi rcsb
molecule tags Hydrolase
source organism Trypanosoma brucei rhodesiense
molecule keywords Cysteine protease
total genus 69
structure length 215
sequence length 215
ec nomenclature
pdb deposition date 2007-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2p7uA00
3I3TA 3KSEA 3F75A 1AYUA 3HWNA 3D6SA 1PPDA 1AU2A 3F5VA 1VSNA 1ZIVA 4I05A 2CB5A 2NQIA 2AYNA 3B79A 2PREA 1VJVA 4N8WA 1BGOA 2YJ8A 3N4CA 4RY2A 1YVBA 1O0EA 5PADA 3DF0A 2DCDA 2AU1A 5EGWA 1MS6A 2NQAA 3CH3X 1U9XA 1MHWA 1CTEA 2YJ2A 3WXEA 4W5BA 2XU3A 1ATKA 1CSBB 3S3RA 4N4ZA 4Q8HA 4PI3A 1A6RA 1PPOA 2PADA 3PW3A 1U9WA 1GECE 6PADA 3BWKA 4BS6A 3KKUA 3QSDA 1TU6A 3OISA 2PNSA 2ACTA 3PNRA 2JQGR 3USVA 1ICFA 1GLOA 9PAPA 4WA6A 2DCBA 2PBHA 1AYVA 4QBBA 1BQIA 5K16A 1NPZA 1QXPA 1EF7A 2FRQA 1KFXL 1CV8A 4YYRA 3E1ZB 2AUXA 5A24A 1PPPA 1QDQA 2DCCA 3P5UA 4QRXA 4CZWA 1TLOA 4FK5A 2VHSA 4P6GA 1CQDA 1K3BB 2AYOA 2DC8A 1U9QX 1CS8A 3K8UA 2AS8A 3AI8A 3KFQA 3K24A 2OZ2A 2H7JA 2FYEA 2HXZA 1CVZA 2B1MA 3HD3A 3IOQA 2E00A 1THEA 4KLBA 2AUZA 4BPVA 1QMYA 1YALA 2IBIA 4HWYA 5JA7A 2O6XA 3N3KA 4DMXA 3IV2A 1CB5A 4G54A 3P5WA 4XUIA 1NB3A 1PIPA 2CIOA 1MEMA 1STFE 1F2CA 2VHFA 3TNXA 3PDFA 2R9OA 4X6HA 1KFUL 3KWBX 2DCAA 2DJGB 3NHEA 3PBHA 2P0RA 4CDDB 1IWDA 4Q8GA 2JQFR 2R9NA 1Q6KA 4BSQA 4OEMA 2R6NA 3H89A 1PCIA 2G8JA 2E02A 4QH6A 3H8BA 3KW9A 4BS5A 2GFOA 2FTDA 3MHSA 4K7CA 4I04A 3HHAA 2HHNA 2AIMA 2G7YA 3OF8A 3U8EA 1HUCB 2GHUA 5CVMA 1GMYA 3IHPA 2DZZA 4YYVA 3OF9A 1PXVA 3MTNA 3HHIA 2ATOA 1S4VA 1AYWA 2P86A 1MIRA 5JH3A 3S3QA 3OVXA 1Y4HA 2AVWA 3LFYA 3ERVA 3QT4A 4X6IA 1YK7A 2HH5A 1MEGA 2E03A 1DF0A 4PP2E 3BOWA 1MDWA 1DEUA 1FH0A 3H7DA 4YV8A 2YJ9A 2BDZA 4W4UA 3I06A 4PP1A 5CHVA 1ITOA 4X6JA 2R9CA 2IPPB 2Y5BA 4XR7A 1EWLA 1F29A 4YYSA 4FJCA 4YYUA 8PCHA 3M99A 5J94A 1ZCMA 3IMAA 2F1GA 3MORA 3O0UA 1X9YA 3RVXA 2FT2A 1AU0A 2P7UA 1JQPA 1F2AA 1AIMA 3KWZA 4CDCB 3CBJA 3P5VA 1PADA 1CPJA 5CVOB 3K9MA 1NLJA 2R9FA 4YYQA 2NQDB 1BP4A 4YVAA 1POPA 2DC6A 3KX1A 3WXFA 2ARYA 5CVNB 1QOLA 3QJ3A 4QRVA 1Y08A 4QRGA 2XU1A 2Y6EA 3MHHA 3RVWA 3WXGA 1GCBA 2XU4A 2YJCA 4I07A 4MZOA 3P5XA 2OULA 4CDFB 1YT7A 2E01A 2FUDA 3BCNA 1KXRA 2DJFB 2FQ9A 3H8CA 3CH2X 1SP4B 1ME3A 2C0YA 3N3GA 5F02A 3V6CA 2B1NA 2FO5A 3O1GA 4AXLA 4N79A 1EWMA 2G8EA 1ME4A 1NQCA 2HD5A 1U9VA 3CBKA 2DC7A 4BQVA 1PE6A 3IEJA 1NB5A 3BC3A 1AU3A 7PCKA 2WBFX 1CJLA 5CHTA 1AU4A 2YJBA 3BPMA 1U5IA 1KHQA 2FRAA 3GCBA 4DMYA 1M6DA 3ZUAA 2OP3A 4FIPA 1EWPA 2XU5A 5EF4A 4OELA 3OVZA 3LXSA 1SNKA 3C9EA 1NL6A 2R9MA 5FPWA 4YYWA 1BY8A 4P6EA 2BDLA 1TL9A 3BPFA 1YK8A 1PBHA 1EWOA 2DZYA 1XKGA 2DC9A 1PPNA 4MZSA 4CDEB 1F2BA 1AECA 2F7DA 4ZUXU 2NQGA 2G6DA 4PADA 3RVVA 4AXMA 3IUTA 3H6SA 3V6EA 4MSXA 1KHPA 4W5CA
chains in the Genus database with same CATH superfamily
3TRKA 3I3TA 3KSEA 3F75A 1AYUA 3HWNA 3D6SA 1PPDA 1AU2A 3F5VA 1VSNA 1ZIVA 4I05A 2CB5A 2NQIA 2J7QA 2AYNA 3B79A 2PREA 1VJVA 2BTWB 4N8WA 3MP2A 3ZNHA 4HXDB 1BGOA 2YJ8A 3N4CA 4RY2A 1YVBA 1O0EA 5PADA 3BBAA 3DF0A 2DCDA 2AU1A 5EGWA 1MS6A 2NQAA 3CH3X 1U9XA 1MHWA 1PVJA 1CTEA 4GUAA 2YJ2A 3WXEA 4W5BA 2XU3A 1ATKA 1CSBB 3S3RA 4N4ZA 4Q8HA 4PI3A 1A6RA 1PPOA 2PADA 3PW3A 1U9WA 1GECE 6PADA 3BWKA 4BS6A 3KKUA 3QSDA 1TU6A 3OISA 2PNSA 2ACTA 3PNRA 2JQGR 3USVA 3IFUA 1ICFA 1GLOA 9PAPA 4WA6A 2DCBA 2PBHA 1AYVA 4QBBA 1BQIA 2JRIA 5K16A 1NPZA 1QXPA 1EF7A 2FRQA 1KFXL 1CV8A 4YYRA 3E1ZB 2AUXA 5A24A 1PPPA 1QDQA 2DCCA 3P5UA 4QRXA 4CZWA 1TLOA 3W31A 4FK5A 2VHSA 4P6GA 3MJ5A 4OVZA 1CQDA 1K3BB 2AYOA 2DC8A 1U9QX 5EZSA 1CS8A 3K8UA 2AS8A 3AI8A 3KFQA 4PT5A 3K24A 2OZ2A 3O65A 2H7JA 2FYEA 2HXZA 1CVZA 2B1MA 3HD3A 3IOQA 2E00A 1THEA 4KLBA 3E9SA 2AUZA 4BPVA 1QMYA 4WURA 1YALA 2IBIA 4HWYA 5JA7A 2O6XA 3N3KA 4DMXA 3IV2A 1CB5A 4G54A 3P5WA 4XUIA 1NB3A 1PIPA 2CIOA 1MEMA 1STFE 1F2CA 2BU3A 2VHFA 3TNXA 3PDFA 2R9OA 2JTCA 4X6HA 1KFUL 3KWBX 2DCAA 2DJGB 2HWKA 2BTWA 3NHEA 3PBHA 2P0RA 4CDDB 1IWDA 4Q8GA 2FE8A 2JQFR 2R9NA 4OW0A 1Q6KA 4BSQA 4OEMA 2R6NA 3H89A 1PCIA 2G8JA 2E02A 4QH6A 3RNVA 3H8BA 3KW9A 4BS5A 2GFOA 3W30A 2FTDA 3MHSA 4K7CA 2Z84A 2J7QC 4I04A 3HHAA 4IUMA 4A5UA 2HHNA 2AIMA 2G7YA 3OF8A 3U8EA 1HUCB 2GHUA 4M0WA 5CVMA 1GMYA 3IHPA 2DZZA 4YYVA 3OF9A 1DKIA 4MI7A 4R3DA 1PXVA 3MTNA 3HHIA 2ATOA 4BOUA 1S4VA 1AYWA 2P86A 1MIRA 5JH3A 3S3QA 3PSEA 3OVXA 1Y4HA 3C0RA 2AVWA 3LFYA 3ERVA 3QT4A 4X6IA 5JZEA 1YK7A 2HH5A 1MEGA 2E03A 1DF0A 4PP2E 3BOWA 1MDWA 1DEUA 1FH0A 1UKFA 3H7DA 4YV8A 2YJ9A 2BDZA 4W4UA 3I06A 4PP1A 4RNAA 4BOPA 3BB7A 5CHVA 1ITOA 4BOZA 4X6JA 2R9CA 2IPPB 2Y5BA 4XR7A 1EWLA 1F29A 4YYSA 4FJCA 4YYUA 8PCHA 3M99A 5J94A 1ZCMA 3IMAA 2F1GA 4D8IA 3MORA 3O0UA 4OVZB 1X9YA 3RVXA 3OQCA 3PHXA 2FT2A 1AU0A 2P7UA 1JQPA 1F2AA 1AIMA 2UZJA 3KWZA 4CDCB 3CBJA 3P5VA 1PADA 4XZXA 1CPJA 5CVOB 3K9MA 1NLJA 2R9FA 4YYQA 2NQDB 1BP4A 4YVAA 5E6JA 1POPA 2DC6A 3KX1A 4RF1A 3PHWA 3WXFA 2ARYA 5CVNB 3B21A 1QOLA 3QJ3A 4QRVA 1Y08A 4QRGA 2XU1A 2Y6EA 2AGAA 3MHHA 3RVWA 3WXGA 1GCBA 2XU4A 2YJCA 4I07A 4MZOA 3P5XA 2OULA 4CDFB 1YT7A 2E01A 2FUDA 3BCNA 1KXRA 2DJFB 2FQ9A 3H8CA 3CH2X 3PRMA 1SP4B 4REZA 4BOQA 1ME3A 2C0YA 3N3GA 5F02A 3V6CA 4MM3B 2B1NA 2FO5A 3O1GA 4AXLA 3PHUA 4N79A 1EWMA 2G8EA 1ME4A 1NQCA 2HD5A 1U9VA 3CBKA 2DC7A 4BQVA 1PE6A 3IEJA 4D8EA 1NB5A 3BC3A 1AU3A 7PCKA 2WBFX 1CJLA 1YZBA 5CHTA 1AU4A 2YJBA 4IP3A 3BPMA 3BY4A 1U5IA 1KHQA 2FRAA 3GCBA 4DMYA 2DOSA 5EZQA 1M6DA 4ZTBA 3PT2A 3ZUAA 2OP3A 4FIPA 1EWPA 2XU5A 5EF4A 4OELA 4RF0A 3OVZA 3LXSA 1SNKA 3C9EA 1NL6A 2R9MA 5FPWA 4YYWA 1BY8A 4D8BA 4P6EA 3TMPA 2BDLA 1TL9A 3BPFA 4P16A 1YK8A 1PBHA 1EWOA 2DZYA 1XKGA 2DC9A 1PPNA 4MZSA 4CDEB 1F2BA 1AECA 2F7DA 4ZUXU 2NQGA 2G6DA 4PADA 3PRPA 5KO3A 3RVVA 4AXMA 3IUTA 4RKXA 4BOSA 3H6SA 3V6EA 4MSXA 1KHPA 3MTVA 4W5CA
chains in the Genus database with same CATH topology
3I3TA 3KSEA 3F75A 1AYUA 3HWNA 3D6SA 1PPDA 1AU2A 3F5VA 1VSNA 1ZIVA 4I05A 2CB5A 2NQIA 4NV7A 2AYNA 3B79A 2PREA 1VJVA 4N8WA 1BGOA 2YJ8A 3N4CA 4RY2A 1YVBA 1O0EA 5PADA 3DF0A 2DCDA 2AU1A 5EGWA 1MS6A 2NQAA 3CH3X 1U9XA 1MHWA 1CTEA 2YJ2A 3WXEA 4W5BA 2XU3A 1ATKA 1CSBB 3S3RA 4N4ZA 4Q8HA 2VFBA 4PI3A 1A6RA 1PPOA 2PADA 3PW3A 1U9WA 1GECE 6PADA 3BWKA 4BS6A 3KKUA 3QSDA 1TU6A 3OISA 2PNSA 2ACTA 3PNRA 2JQGR 3USVA 4BGFA 1ICFA 1GLOA 9PAPA 4WA6A 2DCBA 2PBHA 1AYVA 4QBBA 1BQIA 5K16A 1NPZA 1QXPA 1EF7A 2FRQA 1KFXL 1CV8A 4YYRA 3E1ZB 1E2TA 2AUXA 5A24A 3LTWA 1PPPA 1QDQA 2DCCA 3P5UA 4QRXA 4CZWA 1TLOA 4FK5A 2VHSA 4P6GA 1CQDA 1K3BB 2AYOA 2DC8A 1U9QX 1CS8A 3K8UA 2AS8A 3AI8A 3KFQA 3K24A 2OZ2A 2H7JA 2FYEA 2HXZA 1CVZA 2B1MA 3HD3A 3IOQA 3D9WA 2E00A 1THEA 4KLBA 2AUZA 4BPVA 1QMYA 1YALA 2IBIA 4HWYA 5JA7A 2O6XA 3N3KA 4DMXA 3IV2A 1CB5A 4G54A 3P5WA 4XUIA 1NB3A 1PIPA 2CIOA 1MEMA 1STFE 1F2CA 2VHFA 1GX3A 3TNXA 3PDFA 2R9OA 4X6HA 1KFUL 3KWBX 2DCAA 2DJGB 3NHEA 3PBHA 2P0RA 4CDDB 1IWDA 4Q8GA 2JQFR 2R9NA 1Q6KA 4BSQA 4OEMA 1W6FA 2R6NA 3H89A 1PCIA 2G8JA 2E02A 4QH6A 3H8BA 3KW9A 4BS5A 2GFOA 2FTDA 3MHSA 4K7CA 4I04A 3HHAA 2BSZA 2HHNA 2AIMA 2G7YA 3OF8A 3U8EA 1HUCB 2GHUA 4NV8A 5CVMA 1GMYA 3IHPA 2DZZA 4YYVA 3OF9A 1PXVA 3MTNA 3HHIA 2ATOA 1S4VA 1AYWA 2P86A 1MIRA 5JH3A 3S3QA 3OVXA 1Y4HA 2AVWA 3LFYA 3ERVA 3QT4A 4X6IA 1YK7A 2HH5A 1MEGA 2E03A 1DF0A 4PP2E 3BOWA 1MDWA 1DEUA 1FH0A 3H7DA 4YV8A 2YJ9A 2BDZA 4W4UA 3I06A 4PP1A 5CHVA 1ITOA 4X6JA 2R9CA 2IPPB 2Y5BA 4XR7A 4B55A 1EWLA 1F29A 4YYSA 4FJCA 4C5PA 4YYUA 8PCHA 3M99A 5J94A 1ZCMA 3IMAA 2F1GA 3MORA 3O0UA 1X9YA 3RVXA 2FT2A 1AU0A 2P7UA 1JQPA 1F2AA 1AIMA 3KWZA 4CDCB 3CBJA 3P5VA 1PADA 1CPJA 5CVOB 3K9MA 1NLJA 2R9FA 4YYQA 2NQDB 1W4TA 1BP4A 4YVAA 1POPA 2DC6A 3KX1A 3WXFA 2ARYA 5CVNB 1W5RA 1QOLA 3QJ3A 4QRVA 1Y08A 4QRGA 2XU1A 2Y6EA 3MHHA 3RVWA 3WXGA 1GCBA 2XU4A 2YJCA 4I07A 4MZOA 3P5XA 2OULA 4CDFB 1YT7A 2E01A 2FUDA 3BCNA 1KXRA 2DJFB 2FQ9A 3H8CA 3CH2X 1SP4B 1ME3A 2C0YA 3N3GA 5F02A 3V6CA 2B1NA 2FO5A 3O1GA 4AXLA 4N79A 1EWMA 2G8EA 1ME4A 1NQCA 2HD5A 1U9VA 3CBKA 2DC7A 4BQVA 1PE6A 3IEJA 1NB5A 3BC3A 1AU3A 7PCKA 2WBFX 1CJLA 5CHTA 1AU4A 2YJBA 3BPMA 1U5IA 1KHQA 2FRAA 3GCBA 4DMYA 1M6DA 3ZUAA 2OP3A 4FIPA 1EWPA 2XU5A 5EF4A 4OELA 3OVZA 3LXSA 1SNKA 3C9EA 1NL6A 2R9MA 5FPWA 4YYWA 2VFCA 1BY8A 4P6EA 4GUZA 2BDLA 1TL9A 3BPFA 1YK8A 1PBHA 1EWOA 2DZYA 1XKGA 2DC9A 1PPNA 4MZSA 4CDEB 1F2BA 1AECA 2F7DA 4ZUXU 2NQGA 2G6DA 4PADA 3RVVA 4AXMA 3IUTA 3H6SA 3V6EA 4MSXA 1KHPA 4W5CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I3T A;  3KSE A;  3F75 A;  1AYU A;  3HWN A;  3D6S A;  1PPD A;  1AU2 A;  3F5V A;  1VSN A;  1ZIV A;  4I05 A;  2CB5 A;  2NQI A;  2AYN A;  3B79 A;  2PRE A;  1VJV A;  4N8W A;  1BGO A;  2YJ8 A;  3N4C A;  4RY2 A;  1YVB A;  1O0E A;  5PAD A;  3DF0 A;  2DCD A;  2AU1 A;  5EGW A;  1MS6 A;  2NQA A;  3CH3 X;  1U9X A;  1MHW A;  1CTE A;  2YJ2 A;  3WXE A;  4W5B A;  2XU3 A;  1ATK A;  1CSB B;  3S3R A;  4N4Z A;  4Q8H A;  4PI3 A;  1A6R A;  1PPO A;  2PAD A;  3PW3 A;  1U9W A;  1GEC E;  6PAD A;  3BWK A;  4BS6 A;  3KKU A;  3QSD A;  1TU6 A;  3OIS A;  2PNS A;  2ACT A;  3PNR A;  2JQG R;  3USV A;  1ICF A;  1GLO A;  9PAP A;  4WA6 A;  2DCB A;  2PBH A;  1AYV A;  4QBB A;  1BQI A;  5K16 A;  1NPZ A;  1QXP A;  1EF7 A;  2FRQ A;  1KFX L;  1CV8 A;  4YYR A;  3E1Z B;  2AUX A;  5A24 A;  1PPP A;  1QDQ A;  2DCC A;  3P5U A;  4QRX A;  4CZW A;  1TLO A;  4FK5 A;  2VHS A;  4P6G A;  1CQD A;  1K3B B;  2AYO A;  2DC8 A;  1U9Q X;  1CS8 A;  3K8U A;  2AS8 A;  3AI8 A;  3KFQ A;  3K24 A;  2OZ2 A;  2H7J A;  2FYE A;  2HXZ A;  1CVZ A;  2B1M A;  3HD3 A;  3IOQ A;  2E00 A;  1THE A;  4KLB A;  2AUZ A;  4BPV A;  1QMY A;  1YAL A;  2IBI A;  4HWY A;  5JA7 A;  2O6X A;  3N3K A;  4DMX A;  3IV2 A;  1CB5 A;  4G54 A;  3P5W A;  4XUI A;  1NB3 A;  1PIP A;  2CIO A;  1MEM A;  1STF E;  1F2C A;  2VHF A;  3TNX A;  3PDF A;  2R9O A;  4X6H A;  1KFU L;  3KWB X;  2DCA A;  2DJG B;  3NHE A;  3PBH A;  2P0R A;  4CDD B;  1IWD A;  4Q8G A;  2JQF R;  2R9N A;  1Q6K A;  4BSQ A;  4OEM A;  2R6N A;  3H89 A;  1PCI A;  2G8J A;  2E02 A;  4QH6 A;  3H8B A;  3KW9 A;  4BS5 A;  2GFO A;  2FTD A;  3MHS A;  4K7C A;  4I04 A;  3HHA A;  2HHN A;  2AIM A;  2G7Y A;  3OF8 A;  3U8E A;  1HUC B;  2GHU A;  5CVM A;  1GMY A;  3IHP A;  2DZZ A;  4YYV A;  3OF9 A;  1PXV A;  3MTN A;  3HHI A;  2ATO A;  1S4V A;  1AYW A;  2P86 A;  1MIR A;  5JH3 A;  3S3Q A;  3OVX A;  1Y4H A;  2AVW A;  3LFY A;  3ERV A;  3QT4 A;  4X6I A;  1YK7 A;  2HH5 A;  1MEG A;  2E03 A;  1DF0 A;  4PP2 E;  3BOW A;  1MDW A;  1DEU A;  1FH0 A;  3H7D A;  4YV8 A;  2YJ9 A;  2BDZ A;  4W4U A;  3I06 A;  4PP1 A;  5CHV A;  1ITO A;  4X6J A;  2R9C A;  2IPP B;  2Y5B A;  4XR7 A;  1EWL A;  1F29 A;  4YYS A;  4FJC A;  4YYU A;  8PCH A;  3M99 A;  5J94 A;  1ZCM A;  3IMA A;  2F1G A;  3MOR A;  3O0U A;  1X9Y A;  3RVX A;  2FT2 A;  1AU0 A;  2P7U A;  1JQP A;  1F2A A;  1AIM A;  3KWZ A;  4CDC B;  3CBJ A;  3P5V A;  1PAD A;  1CPJ A;  5CVO B;  3K9M A;  1NLJ A;  2R9F A;  4YYQ A;  2NQD B;  1BP4 A;  4YVA A;  1POP A;  2DC6 A;  3KX1 A;  3WXF A;  2ARY A;  5CVN B;  1QOL A;  3QJ3 A;  4QRV A;  1Y08 A;  4QRG A;  2XU1 A;  2Y6E A;  3MHH A;  3RVW A;  3WXG A;  1GCB A;  2XU4 A;  2YJC A;  4I07 A;  4MZO A;  3P5X A;  2OUL A;  4CDF B;  1YT7 A;  2E01 A;  2FUD A;  3BCN A;  1KXR A;  2DJF B;  2FQ9 A;  3H8C A;  3CH2 X;  1SP4 B;  1ME3 A;  2C0Y A;  3N3G A;  5F02 A;  3V6C A;  2B1N A;  2FO5 A;  3O1G A;  4AXL A;  4N79 A;  1EWM A;  2G8E A;  1ME4 A;  1NQC A;  2HD5 A;  1U9V A;  3CBK A;  2DC7 A;  4BQV A;  1PE6 A;  3IEJ A;  1NB5 A;  3BC3 A;  1AU3 A;  7PCK A;  2WBF X;  1CJL A;  5CHT A;  1AU4 A;  2YJB A;  3BPM A;  1U5I A;  1KHQ A;  2FRA A;  3GCB A;  4DMY A;  1M6D A;  3ZUA A;  2OP3 A;  4FIP A;  1EWP A;  2XU5 A;  5EF4 A;  4OEL A;  3OVZ A;  3LXS A;  1SNK A;  3C9E A;  1NL6 A;  2R9M A;  5FPW A;  4YYW A;  1BY8 A;  4P6E A;  2BDL A;  1TL9 A;  3BPF A;  1YK8 A;  1PBH A;  1EWO A;  2DZY A;  1XKG A;  2DC9 A;  1PPN A;  4MZS A;  4CDE B;  1F2B A;  1AEC A;  2F7D A;  4ZUX U;  2NQG A;  2G6D A;  4PAD A;  3RVV A;  4AXM A;  3IUT A;  3H6S A;  3V6E A;  4MSX A;  1KHP A;  4W5C A; 
#chains in the Genus database with same CATH topology
 3TRK A;  3I3T A;  3KSE A;  3F75 A;  1AYU A;  3HWN A;  3D6S A;  1PPD A;  1AU2 A;  3F5V A;  1VSN A;  1ZIV A;  4I05 A;  2CB5 A;  2NQI A;  2J7Q A;  2AYN A;  3B79 A;  2PRE A;  1VJV A;  2BTW B;  4N8W A;  3MP2 A;  3ZNH A;  4HXD B;  1BGO A;  2YJ8 A;  3N4C A;  4RY2 A;  1YVB A;  1O0E A;  5PAD A;  3BBA A;  3DF0 A;  2DCD A;  2AU1 A;  5EGW A;  1MS6 A;  2NQA A;  3CH3 X;  1U9X A;  1MHW A;  1PVJ A;  1CTE A;  4GUA A;  2YJ2 A;  3WXE A;  4W5B A;  2XU3 A;  1ATK A;  1CSB B;  3S3R A;  4N4Z A;  4Q8H A;  4PI3 A;  1A6R A;  1PPO A;  2PAD A;  3PW3 A;  1U9W A;  1GEC E;  6PAD A;  3BWK A;  4BS6 A;  3KKU A;  3QSD A;  1TU6 A;  3OIS A;  2PNS A;  2ACT A;  3PNR A;  2JQG R;  3USV A;  3IFU A;  1ICF A;  1GLO A;  9PAP A;  4WA6 A;  2DCB A;  2PBH A;  1AYV A;  4QBB A;  1BQI A;  2JRI A;  5K16 A;  1NPZ A;  1QXP A;  1EF7 A;  2FRQ A;  1KFX L;  1CV8 A;  4YYR A;  3E1Z B;  2AUX A;  5A24 A;  1PPP A;  1QDQ A;  2DCC A;  3P5U A;  4QRX A;  4CZW A;  1TLO A;  3W31 A;  4FK5 A;  2VHS A;  4P6G A;  3MJ5 A;  4OVZ A;  1CQD A;  1K3B B;  2AYO A;  2DC8 A;  1U9Q X;  5EZS A;  1CS8 A;  3K8U A;  2AS8 A;  3AI8 A;  3KFQ A;  4PT5 A;  3K24 A;  2OZ2 A;  3O65 A;  2H7J A;  2FYE A;  2HXZ A;  1CVZ A;  2B1M A;  3HD3 A;  3IOQ A;  2E00 A;  1THE A;  4KLB A;  3E9S A;  2AUZ A;  4BPV A;  1QMY A;  4WUR A;  1YAL A;  2IBI A;  4HWY A;  5JA7 A;  2O6X A;  3N3K A;  4DMX A;  3IV2 A;  1CB5 A;  4G54 A;  3P5W A;  4XUI A;  1NB3 A;  1PIP A;  2CIO A;  1MEM A;  1STF E;  1F2C A;  2BU3 A;  2VHF A;  3TNX A;  3PDF A;  2R9O A;  2JTC A;  4X6H A;  1KFU L;  3KWB X;  2DCA A;  2DJG B;  2HWK A;  2BTW A;  3NHE A;  3PBH A;  2P0R A;  4CDD B;  1IWD A;  4Q8G A;  2FE8 A;  2JQF R;  2R9N A;  4OW0 A;  1Q6K A;  4BSQ A;  4OEM A;  2R6N A;  3H89 A;  1PCI A;  2G8J A;  2E02 A;  4QH6 A;  3RNV A;  3H8B A;  3KW9 A;  4BS5 A;  2GFO A;  3W30 A;  2FTD A;  3MHS A;  4K7C A;  2Z84 A;  2J7Q C;  4I04 A;  3HHA A;  4IUM A;  4A5U A;  2HHN A;  2AIM A;  2G7Y A;  3OF8 A;  3U8E A;  1HUC B;  2GHU A;  4M0W A;  5CVM A;  1GMY A;  3IHP A;  2DZZ A;  4YYV A;  3OF9 A;  1DKI A;  4MI7 A;  4R3D A;  1PXV A;  3MTN A;  3HHI A;  2ATO A;  4BOU A;  1S4V A;  1AYW A;  2P86 A;  1MIR A;  5JH3 A;  3S3Q A;  3PSE A;  3OVX A;  1Y4H A;  3C0R A;  2AVW A;  3LFY A;  3ERV A;  3QT4 A;  4X6I A;  5JZE A;  1YK7 A;  2HH5 A;  1MEG A;  2E03 A;  1DF0 A;  4PP2 E;  3BOW A;  1MDW A;  1DEU A;  1FH0 A;  1UKF A;  3H7D A;  4YV8 A;  2YJ9 A;  2BDZ A;  4W4U A;  3I06 A;  4PP1 A;  4RNA A;  4BOP A;  3BB7 A;  5CHV A;  1ITO A;  4BOZ A;  4X6J A;  2R9C A;  2IPP B;  2Y5B A;  4XR7 A;  1EWL A;  1F29 A;  4YYS A;  4FJC A;  4YYU A;  8PCH A;  3M99 A;  5J94 A;  1ZCM A;  3IMA A;  2F1G A;  4D8I A;  3MOR A;  3O0U A;  4OVZ B;  1X9Y A;  3RVX A;  3OQC A;  3PHX A;  2FT2 A;  1AU0 A;  2P7U A;  1JQP A;  1F2A A;  1AIM A;  2UZJ A;  3KWZ A;  4CDC B;  3CBJ A;  3P5V A;  1PAD A;  4XZX A;  1CPJ A;  5CVO B;  3K9M A;  1NLJ A;  2R9F A;  4YYQ A;  2NQD B;  1BP4 A;  4YVA A;  5E6J A;  1POP A;  2DC6 A;  3KX1 A;  4RF1 A;  3PHW A;  3WXF A;  2ARY A;  5CVN B;  3B21 A;  1QOL A;  3QJ3 A;  4QRV A;  1Y08 A;  4QRG A;  2XU1 A;  2Y6E A;  2AGA A;  3MHH A;  3RVW A;  3WXG A;  1GCB A;  2XU4 A;  2YJC A;  4I07 A;  4MZO A;  3P5X A;  2OUL A;  4CDF B;  1YT7 A;  2E01 A;  2FUD A;  3BCN A;  1KXR A;  2DJF B;  2FQ9 A;  3H8C A;  3CH2 X;  3PRM A;  1SP4 B;  4REZ A;  4BOQ A;  1ME3 A;  2C0Y A;  3N3G A;  5F02 A;  3V6C A;  4MM3 B;  2B1N A;  2FO5 A;  3O1G A;  4AXL A;  3PHU A;  4N79 A;  1EWM A;  2G8E A;  1ME4 A;  1NQC A;  2HD5 A;  1U9V A;  3CBK A;  2DC7 A;  4BQV A;  1PE6 A;  3IEJ A;  4D8E A;  1NB5 A;  3BC3 A;  1AU3 A;  7PCK A;  2WBF X;  1CJL A;  1YZB A;  5CHT A;  1AU4 A;  2YJB A;  4IP3 A;  3BPM A;  3BY4 A;  1U5I A;  1KHQ A;  2FRA A;  3GCB A;  4DMY A;  2DOS A;  5EZQ A;  1M6D A;  4ZTB A;  3PT2 A;  3ZUA A;  2OP3 A;  4FIP A;  1EWP A;  2XU5 A;  5EF4 A;  4OEL A;  4RF0 A;  3OVZ A;  3LXS A;  1SNK A;  3C9E A;  1NL6 A;  2R9M A;  5FPW A;  4YYW A;  1BY8 A;  4D8B A;  4P6E A;  3TMP A;  2BDL A;  1TL9 A;  3BPF A;  4P16 A;  1YK8 A;  1PBH A;  1EWO A;  2DZY A;  1XKG A;  2DC9 A;  1PPN A;  4MZS A;  4CDE B;  1F2B A;  1AEC A;  2F7D A;  4ZUX U;  2NQG A;  2G6D A;  4PAD A;  3PRP A;  5KO3 A;  3RVV A;  4AXM A;  3IUT A;  4RKX A;  4BOS A;  3H6S A;  3V6E A;  4MSX A;  1KHP A;  3MTV A;  4W5C A; 
#chains in the Genus database with same CATH homology
 3I3T A;  3KSE A;  3F75 A;  1AYU A;  3HWN A;  3D6S A;  1PPD A;  1AU2 A;  3F5V A;  1VSN A;  1ZIV A;  4I05 A;  2CB5 A;  2NQI A;  4NV7 A;  2AYN A;  3B79 A;  2PRE A;  1VJV A;  4N8W A;  1BGO A;  2YJ8 A;  3N4C A;  4RY2 A;  1YVB A;  1O0E A;  5PAD A;  3DF0 A;  2DCD A;  2AU1 A;  5EGW A;  1MS6 A;  2NQA A;  3CH3 X;  1U9X A;  1MHW A;  1CTE A;  2YJ2 A;  3WXE A;  4W5B A;  2XU3 A;  1ATK A;  1CSB B;  3S3R A;  4N4Z A;  4Q8H A;  2VFB A;  4PI3 A;  1A6R A;  1PPO A;  2PAD A;  3PW3 A;  1U9W A;  1GEC E;  6PAD A;  3BWK A;  4BS6 A;  3KKU A;  3QSD A;  1TU6 A;  3OIS A;  2PNS A;  2ACT A;  3PNR A;  2JQG R;  3USV A;  4BGF A;  1ICF A;  1GLO A;  9PAP A;  4WA6 A;  2DCB A;  2PBH A;  1AYV A;  4QBB A;  1BQI A;  5K16 A;  1NPZ A;  1QXP A;  1EF7 A;  2FRQ A;  1KFX L;  1CV8 A;  4YYR A;  3E1Z B;  1E2T A;  2AUX A;  5A24 A;  3LTW A;  1PPP A;  1QDQ A;  2DCC A;  3P5U A;  4QRX A;  4CZW A;  1TLO A;  4FK5 A;  2VHS A;  4P6G A;  1CQD A;  1K3B B;  2AYO A;  2DC8 A;  1U9Q X;  1CS8 A;  3K8U A;  2AS8 A;  3AI8 A;  3KFQ A;  3K24 A;  2OZ2 A;  2H7J A;  2FYE A;  2HXZ A;  1CVZ A;  2B1M A;  3HD3 A;  3IOQ A;  3D9W A;  2E00 A;  1THE A;  4KLB A;  2AUZ A;  4BPV A;  1QMY A;  1YAL A;  2IBI A;  4HWY A;  5JA7 A;  2O6X A;  3N3K A;  4DMX A;  3IV2 A;  1CB5 A;  4G54 A;  3P5W A;  4XUI A;  1NB3 A;  1PIP A;  2CIO A;  1MEM A;  1STF E;  1F2C A;  2VHF A;  1GX3 A;  3TNX A;  3PDF A;  2R9O A;  4X6H A;  1KFU L;  3KWB X;  2DCA A;  2DJG B;  3NHE A;  3PBH A;  2P0R A;  4CDD B;  1IWD A;  4Q8G A;  2JQF R;  2R9N A;  1Q6K A;  4BSQ A;  4OEM A;  1W6F A;  2R6N A;  3H89 A;  1PCI A;  2G8J A;  2E02 A;  4QH6 A;  3H8B A;  3KW9 A;  4BS5 A;  2GFO A;  2FTD A;  3MHS A;  4K7C A;  4I04 A;  3HHA A;  2BSZ A;  2HHN A;  2AIM A;  2G7Y A;  3OF8 A;  3U8E A;  1HUC B;  2GHU A;  4NV8 A;  5CVM A;  1GMY A;  3IHP A;  2DZZ A;  4YYV A;  3OF9 A;  1PXV A;  3MTN A;  3HHI A;  2ATO A;  1S4V A;  1AYW A;  2P86 A;  1MIR A;  5JH3 A;  3S3Q A;  3OVX A;  1Y4H A;  2AVW A;  3LFY A;  3ERV A;  3QT4 A;  4X6I A;  1YK7 A;  2HH5 A;  1MEG A;  2E03 A;  1DF0 A;  4PP2 E;  3BOW A;  1MDW A;  1DEU A;  1FH0 A;  3H7D A;  4YV8 A;  2YJ9 A;  2BDZ A;  4W4U A;  3I06 A;  4PP1 A;  5CHV A;  1ITO A;  4X6J A;  2R9C A;  2IPP B;  2Y5B A;  4XR7 A;  4B55 A;  1EWL A;  1F29 A;  4YYS A;  4FJC A;  4C5P A;  4YYU A;  8PCH A;  3M99 A;  5J94 A;  1ZCM A;  3IMA A;  2F1G A;  3MOR A;  3O0U A;  1X9Y A;  3RVX A;  2FT2 A;  1AU0 A;  2P7U A;  1JQP A;  1F2A A;  1AIM A;  3KWZ A;  4CDC B;  3CBJ A;  3P5V A;  1PAD A;  1CPJ A;  5CVO B;  3K9M A;  1NLJ A;  2R9F A;  4YYQ A;  2NQD B;  1W4T A;  1BP4 A;  4YVA A;  1POP A;  2DC6 A;  3KX1 A;  3WXF A;  2ARY A;  5CVN B;  1W5R A;  1QOL A;  3QJ3 A;  4QRV A;  1Y08 A;  4QRG A;  2XU1 A;  2Y6E A;  3MHH A;  3RVW A;  3WXG A;  1GCB A;  2XU4 A;  2YJC A;  4I07 A;  4MZO A;  3P5X A;  2OUL A;  4CDF B;  1YT7 A;  2E01 A;  2FUD A;  3BCN A;  1KXR A;  2DJF B;  2FQ9 A;  3H8C A;  3CH2 X;  1SP4 B;  1ME3 A;  2C0Y A;  3N3G A;  5F02 A;  3V6C A;  2B1N A;  2FO5 A;  3O1G A;  4AXL A;  4N79 A;  1EWM A;  2G8E A;  1ME4 A;  1NQC A;  2HD5 A;  1U9V A;  3CBK A;  2DC7 A;  4BQV A;  1PE6 A;  3IEJ A;  1NB5 A;  3BC3 A;  1AU3 A;  7PCK A;  2WBF X;  1CJL A;  5CHT A;  1AU4 A;  2YJB A;  3BPM A;  1U5I A;  1KHQ A;  2FRA A;  3GCB A;  4DMY A;  1M6D A;  3ZUA A;  2OP3 A;  4FIP A;  1EWP A;  2XU5 A;  5EF4 A;  4OEL A;  3OVZ A;  3LXS A;  1SNK A;  3C9E A;  1NL6 A;  2R9M A;  5FPW A;  4YYW A;  2VFC A;  1BY8 A;  4P6E A;  4GUZ A;  2BDL A;  1TL9 A;  3BPF A;  1YK8 A;  1PBH A;  1EWO A;  2DZY A;  1XKG A;  2DC9 A;  1PPN A;  4MZS A;  4CDE B;  1F2B A;  1AEC A;  2F7D A;  4ZUX U;  2NQG A;  2G6D A;  4PAD A;  3RVV A;  4AXM A;  3IUT A;  3H6S A;  3V6E A;  4MSX A;  1KHP A;  4W5C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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