2R9CA

Calpain 1 proteolytic core inactivated by zlak-3001, an alpha-ketoamide
Total Genus 103
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
103
sequence length
322
structure length
322
Chain Sequence
NAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICNLT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Cocrystal structures of primed side-extending alpha-ketoamide inhibitors reveal novel calpain-inhibitor aromatic interactions.
pubmed doi rcsb
molecule tags Hydrolase
source organism Rattus norvegicus
molecule keywords Calpain-1 catalytic subunit
total genus 103
structure length 322
sequence length 322
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2007-09-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2r9cA02
7PCKA 1IWDA 1PBHA 2XU4A 1PE6A 1BP4A 3I3TA 4QBBA 2F1GA 5CHVA 3H8BA 2YJBA 4X6IA 1F2AA 1ITOA 1K3BB 3O0UA 2AUXA 3F5VA 3CH2X 4N79A 1F2CA 5CVMA 4HWYA 4BQVA 1GCBA 5EF4A 2XU3A 1GMYA 2FYEA 1AU2A 1MHWA 1PXVA 1U9XA 3N3GA 3RVVA 3HHIA 4FK5A 3F75A 4YV8A 3S3RA 1U9WA 1CVZA 1PPDA 3ZUAA 1QDQA 3P5WA 1MEGA 1GECE 4AXLA 1X9YA 5JH3A 1F29A 2R9CA 3KKUA 2OP3A 3GCBA 2F7DA 3OVZA 3IEJA 2ARYA 3NHEA 3KW9A 4WA6A 5A24A 4MZOA 3CBKA 3HWNA 1MS6A 1AIMA 1VJVA 4X6JA 1SP4B 2CB5A 3TNXA 5CHTA 1AECA 4PP1A 1PPPA 2CIOA 4FJCA 1SNKA 2VHFA 1U9QX 1CS8A 4MZSA 3MORA 1DF0A 4AXMA 6PADA 2VHSA 2YJ8A 2HD5A 2R6NA 3BPFA 4W4UA 2NQIA 5EGWA 1CJLA 3CH3X 1NLJA 2G8EA 1YK7A 2R9FA 2DJFB 1VSNA 1KFUL 4N4ZA 4P6GA 2NQAA 1XKGA 1HUCB 3AI8A 1O0EA 2DC7A 1FH0A 3KWBX 3I06A 2B1NA 1EWLA 3OF9A 4I05A 4YYUA 4BS6A 5J94A 1QXPA 4YYWA 1U9VA 3WXGA 2E00A 1CV8A 2P86A 1ICFA 4G54A 1CQDA 2B1MA 1QMYA 4CZWA 4QRVA 1U5IA 2P0RA 1EWOA 1ZCMA 2G7YA 1KXRA 4P6EA 3V6EA 3IUTA 3S3QA 2HXZA 3U8EA 3K24A 5CVOB 9PAPA 1STFE 1PPNA 3D6SA 4KLBA 2WBFX 2XU1A 1PADA 4MSXA 1KHPA 2IBIA 3PNRA 2E03A 4OEMA 1CSBB 1NB5A 3K9MA 2R9MA 3BWKA 3H8CA 1EWPA 1AU4A 4BPVA 4PI3A 4W5BA 3OISA 2DCDA 4I04A 2YJ9A 3P5XA 4YYRA 2R9NA 1BGOA 3V6CA 1JQPA 2DC9A 4PADA 1Y08A 3KWZA 2OULA 1GLOA 2OZ2A 1F2BA 1PCIA 3IV2A 3WXEA 1A6RA 4BSQA 5PADA 1EF7A 2YJCA 1EWMA 2FO5A 1DEUA 3O1GA 2NQDB 3QSDA 3MTNA 3WXFA 4Q8HA 2H7JA 4W5CA 2Y6EA 1ZIVA 4X6HA 2GHUA 4CDFB 2GFOA 2HHNA 2FT2A 5FPWA 1ME4A 3BC3A 3QT4A 3BCNA 1BY8A 4Q8GA 2XU5A 3RVXA 5CVNB 3B79A 3KFQA 1AYWA 1AU3A 3ERVA 3MHSA 2AU1A 2G6DA 4YVAA 3PDFA 4FIPA 1M6DA 1MDWA 1YT7A 1TU6A 2G8JA 3USVA 4QH6A 4K7CA 1POPA 4YYSA 3QJ3A 2PBHA 3LFYA 2E01A 1NB3A 1Q6KA 2NQGA 3DF0A 3H7DA 3K8UA 1YVBA 1NQCA 2PADA 1CB5A 1BQIA 4PP2E 1TL9A 1CTEA 2FRQA 4XR7A 4CDEB 1CPJA 1MEMA 3RVWA 2HH5A 4ZUXU 4I07A 2BDLA 1AU0A 4CDDB 2AIMA 2ACTA 8PCHA 1AYUA 3N3KA 4YYQA 3CBJA 2PREA 3OF8A 2R9OA 1KHQA 3OVXA 3PW3A 3HD3A 1ATKA 2FTDA 1MIRA 2YJ2A 2BDZA 4BS5A 2DZYA 1QOLA 2FUDA 3M99A 2IPPB 2DCBA 1THEA 3H6SA 2Y5BA 1KFXL 4DMXA 3IMAA 3PBHA 3C9EA 3BOWA 2FQ9A 2AYNA 2FRAA 2P7UA 4DMYA 4XUIA 3KX1A 1YK8A 2O6XA 3HHAA 3IOQA 3H89A 2JQFR 1ME3A 1AYVA 3LXSA 4QRGA 2ATOA 3N4CA 2AYOA 3IHPA 1PPOA 4N8WA 4YYVA 3E1ZB 1S4VA 1PIPA 2DC8A 2DJGB 3MHHA 2DCCA 1Y4HA 2AS8A 2AUZA 4QRXA 5K16A 1YALA 2DCAA 3P5UA 1TLOA 2DZZA 2DC6A 3KSEA 4RY2A 5F02A 2JQGR 2C0YA 4CDCB 4OELA 1NPZA 5JA7A 3BPMA 2E02A 2AVWA 1NL6A 3P5VA 2PNSA
chains in the Genus database with same CATH superfamily
7PCKA 1IWDA 4D8BA 1PBHA 2XU4A 2UZJA 3O65A 1PE6A 1BP4A 3I3TA 4QBBA 2F1GA 5CHVA 3H8BA 2YJBA 4X6IA 1F2AA 1ITOA 1K3BB 3O0UA 2AUXA 3F5VA 3PHWA 3CH2X 4N79A 1F2CA 5CVMA 4HWYA 4BQVA 4D8EA 1GCBA 5EF4A 2XU3A 1GMYA 2FYEA 1AU2A 1MHWA 1PXVA 1U9XA 3N3GA 3RVVA 3HHIA 4FK5A 3F75A 4PT5A 4YV8A 3S3RA 1U9WA 1CVZA 1PPDA 3ZUAA 1QDQA 3P5WA 1MEGA 1GECE 3IFUA 4AXLA 1X9YA 5JH3A 1F29A 2R9CA 3BBAA 4MM3B 3KKUA 2OP3A 3GCBA 2HWKA 2F7DA 3OVZA 3IEJA 4OVZA 3TMPA 2ARYA 3NHEA 3KW9A 4WA6A 5A24A 4MZOA 3CBKA 3HWNA 4WURA 4RNAA 1MS6A 1AIMA 1VJVA 4M0WA 4X6JA 1SP4B 2CB5A 3TNXA 5CHTA 1AECA 4PP1A 1PPPA 2CIOA 4OVZB 1YZBA 1SNKA 4FJCA 2VHFA 1U9QX 1CS8A 4MZSA 3MORA 1DF0A 4AXMA 4MI7A 4BOPA 6PADA 2VHSA 2YJ8A 2HD5A 2R6NA 3BPFA 3ZNHA 4W4UA 2NQIA 5EGWA 1CJLA 3CH3X 1NLJA 2G8EA 1YK7A 2R9FA 2DJFB 2AGAA 1VSNA 1KFUL 4RKXA 4N4ZA 4RF1A 4P6GA 2NQAA 1XKGA 3BY4A 1HUCB 3AI8A 1O0EA 3MJ5A 4GUAA 2DC7A 3W31A 1FH0A 3KWBX 3I06A 2B1NA 1EWLA 3OF9A 4I05A 4YYUA 4BS6A 3OQCA 5J94A 1QXPA 4YYWA 2BTWA 1U9VA 3PHUA 3WXGA 2E00A 1CV8A 2Z84A 2P86A 1ICFA 4G54A 1CQDA 2B1MA 1QMYA 4CZWA 4IUMA 4QRVA 1U5IA 2P0RA 1EWOA 1ZCMA 2G7YA 1KXRA 4P6EA 3V6EA 3IUTA 3S3QA 2HXZA 3U8EA 3K24A 5CVOB 9PAPA 1STFE 1PPNA 3D6SA 4KLBA 2BTWB 2WBFX 2XU1A 1PADA 4MSXA 1KHPA 2IBIA 3PNRA 2E03A 4OEMA 1CSBB 1NB5A 3K9MA 2R9MA 3BWKA 3H8CA 1EWPA 1AU4A 4BPVA 4BOZA 4PI3A 4W5BA 3OISA 2DCDA 4I04A 4XZXA 2YJ9A 3P5XA 4REZA 4YYRA 3PHXA 2R9NA 1BGOA 3V6CA 4OW0A 1JQPA 2DC9A 4PADA 5E6JA 1Y08A 3KWZA 2OULA 1GLOA 2OZ2A 1F2BA 1PCIA 3IV2A 3WXEA 1A6RA 4BSQA 3BB7A 3B21A 5PADA 1EF7A 2YJCA 1EWMA 2FO5A 1DEUA 3O1GA 2NQDB 3QSDA 3MTNA 3WXFA 4Q8HA 2H7JA 4W5CA 2Y6EA 1ZIVA 4BOSA 3PT2A 4X6HA 2GHUA 4CDFB 3W30A 2GFOA 2HHNA 1DKIA 2FT2A 4P16A 5FPWA 1ME4A 3BC3A 3QT4A 3BCNA 4BOUA 1BY8A 4Q8GA 2XU5A 3RVXA 5CVNB 4D8IA 3B79A 3KFQA 1AYWA 1AU3A 3ERVA 5EZSA 3MHSA 4R3DA 2AU1A 2G6DA 4YVAA 3PDFA 4FIPA 1M6DA 1MDWA 1YT7A 1TU6A 2G8JA 3USVA 4QH6A 1PVJA 4K7CA 1POPA 4YYSA 4ZTBA 3PRMA 3QJ3A 2PBHA 3LFYA 2E01A 1NB3A 3PSEA 1Q6KA 2NQGA 3DF0A 3H7DA 3K8UA 1YVBA 1NQCA 2PADA 1CB5A 1BQIA 4PP2E 1TL9A 1CTEA 3RNVA 2FRQA 4XR7A 4CDEB 1CPJA 3MP2A 1MEMA 3RVWA 5KO3A 2BU3A 4IP3A 4HXDB 2HH5A 4ZUXU 4I07A 3PRPA 2BDLA 1AU0A 4CDDB 2AIMA 2ACTA 8PCHA 1AYUA 3N3KA 4YYQA 3CBJA 2PREA 3OF8A 3C0RA 2R9OA 1KHQA 3OVXA 3PW3A 3HD3A 1ATKA 2FTDA 1MIRA 2YJ2A 2BDZA 4BS5A 2DZYA 1QOLA 2FUDA 3M99A 5JZEA 2IPPB 2DCBA 1THEA 3H6SA 2Y5BA 1KFXL 4DMXA 3IMAA 3PBHA 3C9EA 3BOWA 2FQ9A 4RF0A 2AYNA 2FRAA 2P7UA 4DMYA 4XUIA 3KX1A 1YK8A 2O6XA 3HHAA 3E9SA 2JRIA 3IOQA 3H89A 2JQFR 1ME3A 1UKFA 1AYVA 4A5UA 3LXSA 4QRGA 2ATOA 3N4CA 2AYOA 3IHPA 2JTCA 2J7QC 2J7QA 3MTVA 1PPOA 5EZQA 2DOSA 4N8WA 4YYVA 3E1ZB 1S4VA 1PIPA 2DC8A 2FE8A 2DJGB 3MHHA 2DCCA 1Y4HA 2AS8A 2AUZA 4QRXA 5K16A 1YALA 2DCAA 3P5UA 4BOQA 1TLOA 3TRKA 2DZZA 2DC6A 3KSEA 4RY2A 5F02A 2JQGR 2C0YA 4CDCB 4OELA 1NPZA 5JA7A 3BPMA 2E02A 2AVWA 1NL6A 3P5VA 2PNSA
chains in the Genus database with same CATH topology
7PCKA 1IWDA 1PBHA 2XU4A 1PE6A 1BP4A 3I3TA 4QBBA 2F1GA 5CHVA 3H8BA 2YJBA 4X6IA 1F2AA 1ITOA 1K3BB 3O0UA 2AUXA 3F5VA 3CH2X 4N79A 1F2CA 5CVMA 4HWYA 4BQVA 1GCBA 5EF4A 2XU3A 1GMYA 2FYEA 1AU2A 1MHWA 1PXVA 1U9XA 3N3GA 3RVVA 3HHIA 4FK5A 3F75A 4YV8A 3S3RA 1U9WA 1CVZA 1PPDA 3ZUAA 1QDQA 3P5WA 1MEGA 1GECE 4AXLA 1X9YA 5JH3A 1F29A 2R9CA 3KKUA 2OP3A 3GCBA 2F7DA 3OVZA 3IEJA 2ARYA 3NHEA 3KW9A 4WA6A 5A24A 3D9WA 4MZOA 3CBKA 3HWNA 1MS6A 1AIMA 1VJVA 4X6JA 1SP4B 2CB5A 3TNXA 5CHTA 1AECA 4PP1A 1PPPA 1W6FA 2CIOA 4FJCA 1SNKA 2VHFA 1U9QX 1CS8A 4MZSA 3MORA 1DF0A 4AXMA 6PADA 2VHSA 2YJ8A 2HD5A 2R6NA 3BPFA 4W4UA 2NQIA 5EGWA 1CJLA 3CH3X 1NLJA 2G8EA 1YK7A 2R9FA 2DJFB 1VSNA 1KFUL 4N4ZA 4P6GA 2NQAA 1XKGA 2VFBA 4NV7A 4B55A 1HUCB 3AI8A 1O0EA 2DC7A 1FH0A 3KWBX 3I06A 2B1NA 1EWLA 3OF9A 4I05A 4YYUA 4BS6A 5J94A 1QXPA 4YYWA 1U9VA 3WXGA 2E00A 1CV8A 2P86A 1ICFA 4G54A 1CQDA 2B1MA 1QMYA 4CZWA 4QRVA 1U5IA 2P0RA 1EWOA 1ZCMA 2G7YA 1KXRA 4P6EA 3V6EA 3IUTA 3S3QA 2HXZA 3U8EA 3K24A 1W4TA 5CVOB 9PAPA 1STFE 1PPNA 3D6SA 4KLBA 2WBFX 2XU1A 1PADA 4GUZA 4MSXA 1KHPA 2IBIA 3PNRA 2E03A 4OEMA 1CSBB 1NB5A 3K9MA 2R9MA 3BWKA 3H8CA 1EWPA 1AU4A 4BPVA 4PI3A 4W5BA 1W5RA 3OISA 2DCDA 4I04A 2YJ9A 3P5XA 4YYRA 2R9NA 1BGOA 3V6CA 1JQPA 2DC9A 4PADA 1Y08A 3KWZA 2OULA 1GLOA 2OZ2A 1F2BA 1PCIA 3IV2A 3WXEA 1A6RA 4BSQA 5PADA 1EF7A 2YJCA 1EWMA 2FO5A 1DEUA 3O1GA 2NQDB 3QSDA 3MTNA 3WXFA 4Q8HA 2H7JA 4W5CA 2Y6EA 1ZIVA 4X6HA 2GHUA 4BGFA 4CDFB 2GFOA 2HHNA 2FT2A 5FPWA 1ME4A 3BC3A 3QT4A 3BCNA 1BY8A 4Q8GA 2XU5A 3RVXA 5CVNB 3B79A 3KFQA 1AYWA 1AU3A 3ERVA 3MHSA 2AU1A 2G6DA 4YVAA 3PDFA 4FIPA 1M6DA 1MDWA 1YT7A 1TU6A 2G8JA 3USVA 4QH6A 4K7CA 1POPA 4YYSA 3QJ3A 2PBHA 3LFYA 2E01A 1NB3A 1Q6KA 2NQGA 3DF0A 3H7DA 3K8UA 1YVBA 1NQCA 2PADA 2VFCA 1CB5A 1BQIA 4PP2E 1TL9A 1CTEA 2FRQA 4XR7A 4CDEB 4C5PA 1CPJA 1MEMA 3RVWA 2HH5A 4ZUXU 4I07A 2BDLA 1AU0A 4CDDB 2AIMA 2ACTA 8PCHA 1AYUA 3N3KA 4YYQA 3CBJA 2PREA 3OF8A 2R9OA 1KHQA 3OVXA 3PW3A 3HD3A 3LTWA 1ATKA 2FTDA 1MIRA 2YJ2A 2BDZA 4BS5A 2DZYA 1QOLA 2FUDA 3M99A 2IPPB 2DCBA 1THEA 3H6SA 2Y5BA 1KFXL 4DMXA 3IMAA 3PBHA 3C9EA 3BOWA 2FQ9A 2AYNA 2FRAA 2P7UA 4DMYA 4XUIA 3KX1A 1YK8A 2O6XA 3HHAA 3IOQA 3H89A 2JQFR 1ME3A 1AYVA 3LXSA 4QRGA 2ATOA 3N4CA 2AYOA 3IHPA 1PPOA 4N8WA 4YYVA 3E1ZB 1S4VA 2BSZA 4NV8A 1PIPA 2DC8A 2DJGB 3MHHA 2DCCA 1Y4HA 1E2TA 2AS8A 2AUZA 4QRXA 5K16A 1YALA 2DCAA 3P5UA 1TLOA 2DZZA 2DC6A 3KSEA 4RY2A 5F02A 2JQGR 2C0YA 4CDCB 4OELA 1NPZA 5JA7A 3BPMA 2E02A 2AVWA 1NL6A 3P5VA 1GX3A 2PNSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 7PCK A;  1IWD A;  1PBH A;  2XU4 A;  1PE6 A;  1BP4 A;  3I3T A;  4QBB A;  2F1G A;  5CHV A;  3H8B A;  2YJB A;  4X6I A;  1F2A A;  1ITO A;  1K3B B;  3O0U A;  2AUX A;  3F5V A;  3CH2 X;  4N79 A;  1F2C A;  5CVM A;  4HWY A;  4BQV A;  1GCB A;  5EF4 A;  2XU3 A;  1GMY A;  2FYE A;  1AU2 A;  1MHW A;  1PXV A;  1U9X A;  3N3G A;  3RVV A;  3HHI A;  4FK5 A;  3F75 A;  4YV8 A;  3S3R A;  1U9W A;  1CVZ A;  1PPD A;  3ZUA A;  1QDQ A;  3P5W A;  1MEG A;  1GEC E;  4AXL A;  1X9Y A;  5JH3 A;  1F29 A;  2R9C A;  3KKU A;  2OP3 A;  3GCB A;  2F7D A;  3OVZ A;  3IEJ A;  2ARY A;  3NHE A;  3KW9 A;  4WA6 A;  5A24 A;  4MZO A;  3CBK A;  3HWN A;  1MS6 A;  1AIM A;  1VJV A;  4X6J A;  1SP4 B;  2CB5 A;  3TNX A;  5CHT A;  1AEC A;  4PP1 A;  1PPP A;  2CIO A;  4FJC A;  1SNK A;  2VHF A;  1U9Q X;  1CS8 A;  4MZS A;  3MOR A;  1DF0 A;  4AXM A;  6PAD A;  2VHS A;  2YJ8 A;  2HD5 A;  2R6N A;  3BPF A;  4W4U A;  2NQI A;  5EGW A;  1CJL A;  3CH3 X;  1NLJ A;  2G8E A;  1YK7 A;  2R9F A;  2DJF B;  1VSN A;  1KFU L;  4N4Z A;  4P6G A;  2NQA A;  1XKG A;  1HUC B;  3AI8 A;  1O0E A;  2DC7 A;  1FH0 A;  3KWB X;  3I06 A;  2B1N A;  1EWL A;  3OF9 A;  4I05 A;  4YYU A;  4BS6 A;  5J94 A;  1QXP A;  4YYW A;  1U9V A;  3WXG A;  2E00 A;  1CV8 A;  2P86 A;  1ICF A;  4G54 A;  1CQD A;  2B1M A;  1QMY A;  4CZW A;  4QRV A;  1U5I A;  2P0R A;  1EWO A;  1ZCM A;  2G7Y A;  1KXR A;  4P6E A;  3V6E A;  3IUT A;  3S3Q A;  2HXZ A;  3U8E A;  3K24 A;  5CVO B;  9PAP A;  1STF E;  1PPN A;  3D6S A;  4KLB A;  2WBF X;  2XU1 A;  1PAD A;  4MSX A;  1KHP A;  2IBI A;  3PNR A;  2E03 A;  4OEM A;  1CSB B;  1NB5 A;  3K9M A;  2R9M A;  3BWK A;  3H8C A;  1EWP A;  1AU4 A;  4BPV A;  4PI3 A;  4W5B A;  3OIS A;  2DCD A;  4I04 A;  2YJ9 A;  3P5X A;  4YYR A;  2R9N A;  1BGO A;  3V6C A;  1JQP A;  2DC9 A;  4PAD A;  1Y08 A;  3KWZ A;  2OUL A;  1GLO A;  2OZ2 A;  1F2B A;  1PCI A;  3IV2 A;  3WXE A;  1A6R A;  4BSQ A;  5PAD A;  1EF7 A;  2YJC A;  1EWM A;  2FO5 A;  1DEU A;  3O1G A;  2NQD B;  3QSD A;  3MTN A;  3WXF A;  4Q8H A;  2H7J A;  4W5C A;  2Y6E A;  1ZIV A;  4X6H A;  2GHU A;  4CDF B;  2GFO A;  2HHN A;  2FT2 A;  5FPW A;  1ME4 A;  3BC3 A;  3QT4 A;  3BCN A;  1BY8 A;  4Q8G A;  2XU5 A;  3RVX A;  5CVN B;  3B79 A;  3KFQ A;  1AYW A;  1AU3 A;  3ERV A;  3MHS A;  2AU1 A;  2G6D A;  4YVA A;  3PDF A;  4FIP A;  1M6D A;  1MDW A;  1YT7 A;  1TU6 A;  2G8J A;  3USV A;  4QH6 A;  4K7C A;  1POP A;  4YYS A;  3QJ3 A;  2PBH A;  3LFY A;  2E01 A;  1NB3 A;  1Q6K A;  2NQG A;  3DF0 A;  3H7D A;  3K8U A;  1YVB A;  1NQC A;  2PAD A;  1CB5 A;  1BQI A;  4PP2 E;  1TL9 A;  1CTE A;  2FRQ A;  4XR7 A;  4CDE B;  1CPJ A;  1MEM A;  3RVW A;  2HH5 A;  4ZUX U;  4I07 A;  2BDL A;  1AU0 A;  4CDD B;  2AIM A;  2ACT A;  8PCH A;  1AYU A;  3N3K A;  4YYQ A;  3CBJ A;  2PRE A;  3OF8 A;  2R9O A;  1KHQ A;  3OVX A;  3PW3 A;  3HD3 A;  1ATK A;  2FTD A;  1MIR A;  2YJ2 A;  2BDZ A;  4BS5 A;  2DZY A;  1QOL A;  2FUD A;  3M99 A;  2IPP B;  2DCB A;  1THE A;  3H6S A;  2Y5B A;  1KFX L;  4DMX A;  3IMA A;  3PBH A;  3C9E A;  3BOW A;  2FQ9 A;  2AYN A;  2FRA A;  2P7U A;  4DMY A;  4XUI A;  3KX1 A;  1YK8 A;  2O6X A;  3HHA A;  3IOQ A;  3H89 A;  2JQF R;  1ME3 A;  1AYV A;  3LXS A;  4QRG A;  2ATO A;  3N4C A;  2AYO A;  3IHP A;  1PPO A;  4N8W A;  4YYV A;  3E1Z B;  1S4V A;  1PIP A;  2DC8 A;  2DJG B;  3MHH A;  2DCC A;  1Y4H A;  2AS8 A;  2AUZ A;  4QRX A;  5K16 A;  1YAL A;  2DCA A;  3P5U A;  1TLO A;  2DZZ A;  2DC6 A;  3KSE A;  4RY2 A;  5F02 A;  2JQG R;  2C0Y A;  4CDC B;  4OEL A;  1NPZ A;  5JA7 A;  3BPM A;  2E02 A;  2AVW A;  1NL6 A;  3P5V A;  2PNS A; 
#chains in the Genus database with same CATH topology
 7PCK A;  1IWD A;  4D8B A;  1PBH A;  2XU4 A;  2UZJ A;  3O65 A;  1PE6 A;  1BP4 A;  3I3T A;  4QBB A;  2F1G A;  5CHV A;  3H8B A;  2YJB A;  4X6I A;  1F2A A;  1ITO A;  1K3B B;  3O0U A;  2AUX A;  3F5V A;  3PHW A;  3CH2 X;  4N79 A;  1F2C A;  5CVM A;  4HWY A;  4BQV A;  4D8E A;  1GCB A;  5EF4 A;  2XU3 A;  1GMY A;  2FYE A;  1AU2 A;  1MHW A;  1PXV A;  1U9X A;  3N3G A;  3RVV A;  3HHI A;  4FK5 A;  3F75 A;  4PT5 A;  4YV8 A;  3S3R A;  1U9W A;  1CVZ A;  1PPD A;  3ZUA A;  1QDQ A;  3P5W A;  1MEG A;  1GEC E;  3IFU A;  4AXL A;  1X9Y A;  5JH3 A;  1F29 A;  2R9C A;  3BBA A;  4MM3 B;  3KKU A;  2OP3 A;  3GCB A;  2HWK A;  2F7D A;  3OVZ A;  3IEJ A;  4OVZ A;  3TMP A;  2ARY A;  3NHE A;  3KW9 A;  4WA6 A;  5A24 A;  4MZO A;  3CBK A;  3HWN A;  4WUR A;  4RNA A;  1MS6 A;  1AIM A;  1VJV A;  4M0W A;  4X6J A;  1SP4 B;  2CB5 A;  3TNX A;  5CHT A;  1AEC A;  4PP1 A;  1PPP A;  2CIO A;  4OVZ B;  1YZB A;  1SNK A;  4FJC A;  2VHF A;  1U9Q X;  1CS8 A;  4MZS A;  3MOR A;  1DF0 A;  4AXM A;  4MI7 A;  4BOP A;  6PAD A;  2VHS A;  2YJ8 A;  2HD5 A;  2R6N A;  3BPF A;  3ZNH A;  4W4U A;  2NQI A;  5EGW A;  1CJL A;  3CH3 X;  1NLJ A;  2G8E A;  1YK7 A;  2R9F A;  2DJF B;  2AGA A;  1VSN A;  1KFU L;  4RKX A;  4N4Z A;  4RF1 A;  4P6G A;  2NQA A;  1XKG A;  3BY4 A;  1HUC B;  3AI8 A;  1O0E A;  3MJ5 A;  4GUA A;  2DC7 A;  3W31 A;  1FH0 A;  3KWB X;  3I06 A;  2B1N A;  1EWL A;  3OF9 A;  4I05 A;  4YYU A;  4BS6 A;  3OQC A;  5J94 A;  1QXP A;  4YYW A;  2BTW A;  1U9V A;  3PHU A;  3WXG A;  2E00 A;  1CV8 A;  2Z84 A;  2P86 A;  1ICF A;  4G54 A;  1CQD A;  2B1M A;  1QMY A;  4CZW A;  4IUM A;  4QRV A;  1U5I A;  2P0R A;  1EWO A;  1ZCM A;  2G7Y A;  1KXR A;  4P6E A;  3V6E A;  3IUT A;  3S3Q A;  2HXZ A;  3U8E A;  3K24 A;  5CVO B;  9PAP A;  1STF E;  1PPN A;  3D6S A;  4KLB A;  2BTW B;  2WBF X;  2XU1 A;  1PAD A;  4MSX A;  1KHP A;  2IBI A;  3PNR A;  2E03 A;  4OEM A;  1CSB B;  1NB5 A;  3K9M A;  2R9M A;  3BWK A;  3H8C A;  1EWP A;  1AU4 A;  4BPV A;  4BOZ A;  4PI3 A;  4W5B A;  3OIS A;  2DCD A;  4I04 A;  4XZX A;  2YJ9 A;  3P5X A;  4REZ A;  4YYR A;  3PHX A;  2R9N A;  1BGO A;  3V6C A;  4OW0 A;  1JQP A;  2DC9 A;  4PAD A;  5E6J A;  1Y08 A;  3KWZ A;  2OUL A;  1GLO A;  2OZ2 A;  1F2B A;  1PCI A;  3IV2 A;  3WXE A;  1A6R A;  4BSQ A;  3BB7 A;  3B21 A;  5PAD A;  1EF7 A;  2YJC A;  1EWM A;  2FO5 A;  1DEU A;  3O1G A;  2NQD B;  3QSD A;  3MTN A;  3WXF A;  4Q8H A;  2H7J A;  4W5C A;  2Y6E A;  1ZIV A;  4BOS A;  3PT2 A;  4X6H A;  2GHU A;  4CDF B;  3W30 A;  2GFO A;  2HHN A;  1DKI A;  2FT2 A;  4P16 A;  5FPW A;  1ME4 A;  3BC3 A;  3QT4 A;  3BCN A;  4BOU A;  1BY8 A;  4Q8G A;  2XU5 A;  3RVX A;  5CVN B;  4D8I A;  3B79 A;  3KFQ A;  1AYW A;  1AU3 A;  3ERV A;  5EZS A;  3MHS A;  4R3D A;  2AU1 A;  2G6D A;  4YVA A;  3PDF A;  4FIP A;  1M6D A;  1MDW A;  1YT7 A;  1TU6 A;  2G8J A;  3USV A;  4QH6 A;  1PVJ A;  4K7C A;  1POP A;  4YYS A;  4ZTB A;  3PRM A;  3QJ3 A;  2PBH A;  3LFY A;  2E01 A;  1NB3 A;  3PSE A;  1Q6K A;  2NQG A;  3DF0 A;  3H7D A;  3K8U A;  1YVB A;  1NQC A;  2PAD A;  1CB5 A;  1BQI A;  4PP2 E;  1TL9 A;  1CTE A;  3RNV A;  2FRQ A;  4XR7 A;  4CDE B;  1CPJ A;  3MP2 A;  1MEM A;  3RVW A;  5KO3 A;  2BU3 A;  4IP3 A;  4HXD B;  2HH5 A;  4ZUX U;  4I07 A;  3PRP A;  2BDL A;  1AU0 A;  4CDD B;  2AIM A;  2ACT A;  8PCH A;  1AYU A;  3N3K A;  4YYQ A;  3CBJ A;  2PRE A;  3OF8 A;  3C0R A;  2R9O A;  1KHQ A;  3OVX A;  3PW3 A;  3HD3 A;  1ATK A;  2FTD A;  1MIR A;  2YJ2 A;  2BDZ A;  4BS5 A;  2DZY A;  1QOL A;  2FUD A;  3M99 A;  5JZE A;  2IPP B;  2DCB A;  1THE A;  3H6S A;  2Y5B A;  1KFX L;  4DMX A;  3IMA A;  3PBH A;  3C9E A;  3BOW A;  2FQ9 A;  4RF0 A;  2AYN A;  2FRA A;  2P7U A;  4DMY A;  4XUI A;  3KX1 A;  1YK8 A;  2O6X A;  3HHA A;  3E9S A;  2JRI A;  3IOQ A;  3H89 A;  2JQF R;  1ME3 A;  1UKF A;  1AYV A;  4A5U A;  3LXS A;  4QRG A;  2ATO A;  3N4C A;  2AYO A;  3IHP A;  2JTC A;  2J7Q C;  2J7Q A;  3MTV A;  1PPO A;  5EZQ A;  2DOS A;  4N8W A;  4YYV A;  3E1Z B;  1S4V A;  1PIP A;  2DC8 A;  2FE8 A;  2DJG B;  3MHH A;  2DCC A;  1Y4H A;  2AS8 A;  2AUZ A;  4QRX A;  5K16 A;  1YAL A;  2DCA A;  3P5U A;  4BOQ A;  1TLO A;  3TRK A;  2DZZ A;  2DC6 A;  3KSE A;  4RY2 A;  5F02 A;  2JQG R;  2C0Y A;  4CDC B;  4OEL A;  1NPZ A;  5JA7 A;  3BPM A;  2E02 A;  2AVW A;  1NL6 A;  3P5V A;  2PNS A; 
#chains in the Genus database with same CATH homology
 7PCK A;  1IWD A;  1PBH A;  2XU4 A;  1PE6 A;  1BP4 A;  3I3T A;  4QBB A;  2F1G A;  5CHV A;  3H8B A;  2YJB A;  4X6I A;  1F2A A;  1ITO A;  1K3B B;  3O0U A;  2AUX A;  3F5V A;  3CH2 X;  4N79 A;  1F2C A;  5CVM A;  4HWY A;  4BQV A;  1GCB A;  5EF4 A;  2XU3 A;  1GMY A;  2FYE A;  1AU2 A;  1MHW A;  1PXV A;  1U9X A;  3N3G A;  3RVV A;  3HHI A;  4FK5 A;  3F75 A;  4YV8 A;  3S3R A;  1U9W A;  1CVZ A;  1PPD A;  3ZUA A;  1QDQ A;  3P5W A;  1MEG A;  1GEC E;  4AXL A;  1X9Y A;  5JH3 A;  1F29 A;  2R9C A;  3KKU A;  2OP3 A;  3GCB A;  2F7D A;  3OVZ A;  3IEJ A;  2ARY A;  3NHE A;  3KW9 A;  4WA6 A;  5A24 A;  3D9W A;  4MZO A;  3CBK A;  3HWN A;  1MS6 A;  1AIM A;  1VJV A;  4X6J A;  1SP4 B;  2CB5 A;  3TNX A;  5CHT A;  1AEC A;  4PP1 A;  1PPP A;  1W6F A;  2CIO A;  4FJC A;  1SNK A;  2VHF A;  1U9Q X;  1CS8 A;  4MZS A;  3MOR A;  1DF0 A;  4AXM A;  6PAD A;  2VHS A;  2YJ8 A;  2HD5 A;  2R6N A;  3BPF A;  4W4U A;  2NQI A;  5EGW A;  1CJL A;  3CH3 X;  1NLJ A;  2G8E A;  1YK7 A;  2R9F A;  2DJF B;  1VSN A;  1KFU L;  4N4Z A;  4P6G A;  2NQA A;  1XKG A;  2VFB A;  4NV7 A;  4B55 A;  1HUC B;  3AI8 A;  1O0E A;  2DC7 A;  1FH0 A;  3KWB X;  3I06 A;  2B1N A;  1EWL A;  3OF9 A;  4I05 A;  4YYU A;  4BS6 A;  5J94 A;  1QXP A;  4YYW A;  1U9V A;  3WXG A;  2E00 A;  1CV8 A;  2P86 A;  1ICF A;  4G54 A;  1CQD A;  2B1M A;  1QMY A;  4CZW A;  4QRV A;  1U5I A;  2P0R A;  1EWO A;  1ZCM A;  2G7Y A;  1KXR A;  4P6E A;  3V6E A;  3IUT A;  3S3Q A;  2HXZ A;  3U8E A;  3K24 A;  1W4T A;  5CVO B;  9PAP A;  1STF E;  1PPN A;  3D6S A;  4KLB A;  2WBF X;  2XU1 A;  1PAD A;  4GUZ A;  4MSX A;  1KHP A;  2IBI A;  3PNR A;  2E03 A;  4OEM A;  1CSB B;  1NB5 A;  3K9M A;  2R9M A;  3BWK A;  3H8C A;  1EWP A;  1AU4 A;  4BPV A;  4PI3 A;  4W5B A;  1W5R A;  3OIS A;  2DCD A;  4I04 A;  2YJ9 A;  3P5X A;  4YYR A;  2R9N A;  1BGO A;  3V6C A;  1JQP A;  2DC9 A;  4PAD A;  1Y08 A;  3KWZ A;  2OUL A;  1GLO A;  2OZ2 A;  1F2B A;  1PCI A;  3IV2 A;  3WXE A;  1A6R A;  4BSQ A;  5PAD A;  1EF7 A;  2YJC A;  1EWM A;  2FO5 A;  1DEU A;  3O1G A;  2NQD B;  3QSD A;  3MTN A;  3WXF A;  4Q8H A;  2H7J A;  4W5C A;  2Y6E A;  1ZIV A;  4X6H A;  2GHU A;  4BGF A;  4CDF B;  2GFO A;  2HHN A;  2FT2 A;  5FPW A;  1ME4 A;  3BC3 A;  3QT4 A;  3BCN A;  1BY8 A;  4Q8G A;  2XU5 A;  3RVX A;  5CVN B;  3B79 A;  3KFQ A;  1AYW A;  1AU3 A;  3ERV A;  3MHS A;  2AU1 A;  2G6D A;  4YVA A;  3PDF A;  4FIP A;  1M6D A;  1MDW A;  1YT7 A;  1TU6 A;  2G8J A;  3USV A;  4QH6 A;  4K7C A;  1POP A;  4YYS A;  3QJ3 A;  2PBH A;  3LFY A;  2E01 A;  1NB3 A;  1Q6K A;  2NQG A;  3DF0 A;  3H7D A;  3K8U A;  1YVB A;  1NQC A;  2PAD A;  2VFC A;  1CB5 A;  1BQI A;  4PP2 E;  1TL9 A;  1CTE A;  2FRQ A;  4XR7 A;  4CDE B;  4C5P A;  1CPJ A;  1MEM A;  3RVW A;  2HH5 A;  4ZUX U;  4I07 A;  2BDL A;  1AU0 A;  4CDD B;  2AIM A;  2ACT A;  8PCH A;  1AYU A;  3N3K A;  4YYQ A;  3CBJ A;  2PRE A;  3OF8 A;  2R9O A;  1KHQ A;  3OVX A;  3PW3 A;  3HD3 A;  3LTW A;  1ATK A;  2FTD A;  1MIR A;  2YJ2 A;  2BDZ A;  4BS5 A;  2DZY A;  1QOL A;  2FUD A;  3M99 A;  2IPP B;  2DCB A;  1THE A;  3H6S A;  2Y5B A;  1KFX L;  4DMX A;  3IMA A;  3PBH A;  3C9E A;  3BOW A;  2FQ9 A;  2AYN A;  2FRA A;  2P7U A;  4DMY A;  4XUI A;  3KX1 A;  1YK8 A;  2O6X A;  3HHA A;  3IOQ A;  3H89 A;  2JQF R;  1ME3 A;  1AYV A;  3LXS A;  4QRG A;  2ATO A;  3N4C A;  2AYO A;  3IHP A;  1PPO A;  4N8W A;  4YYV A;  3E1Z B;  1S4V A;  2BSZ A;  4NV8 A;  1PIP A;  2DC8 A;  2DJG B;  3MHH A;  2DCC A;  1Y4H A;  1E2T A;  2AS8 A;  2AUZ A;  4QRX A;  5K16 A;  1YAL A;  2DCA A;  3P5U A;  1TLO A;  2DZZ A;  2DC6 A;  3KSE A;  4RY2 A;  5F02 A;  2JQG R;  2C0Y A;  4CDC B;  4OEL A;  1NPZ A;  5JA7 A;  3BPM A;  2E02 A;  2AVW A;  1NL6 A;  3P5V A;  1GX3 A;  2PNS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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