2R9CA

Calpain 1 proteolytic core inactivated by zlak-3001, an alpha-ketoamide
Total Genus 103
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
103
sequence length
322
structure length
322
Chain Sequence
NAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICNLT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Calpain-1 catalytic subunit
publication title Cocrystal structures of primed side-extending alpha-ketoamide inhibitors reveal novel calpain-inhibitor aromatic interactions.
pubmed doi rcsb
source organism Rattus norvegicus
molecule tags Hydrolase
total genus 103
structure length 322
sequence length 322
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2007-09-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2r9cA02
1QMYA 1NLJA 1F29A 1PE6A 3K24A 4YYQA 3KSEA 2VHSA 1KHQA 1POPA 1CQDA 1MS6A 1EWLA 3ZUAA 1U5IA 4QRVA 1M6DA 1F2AA 2DZYA 2G7YA 5K16A 1GCBA 4P6EA 2VHFA 1PPPA 3DF0A 1F2CA 2OULA 2XU5A 4XUIA 9PAPA 1BGOA 1CSBB 2YJCA 2AVWA 3S3RA 1NPZA 2ARYA 1MIRA 3PNRA 2OP3A 1DF0A 2DC6A 3P5WA 4PP2E 1CV8A 2FT2A 3OISA 2HXZA 3P5VA 1AU3A 3WXGA 3F75A 2PADA 1EWPA 2NQGA 2DJGB 2JQGR 3S3QA 2AIMA 3IHPA 3WXFA 4YVAA 2NQIA 2HD5A 4N4ZA 3H8CA 4Q8HA 5CVOB 1PCIA 5PADA 4RY2A 3CH3X 1MHWA 2DCBA 2CB5A 4XR7A 3F5VA 1QDQA 3QJ3A 5JA7A 2IPPB 4AXLA 2FYEA 2H7JA 7PCKA 3ERVA 2GHUA 4QRXA 1AU0A 2XU4A 4W5CA 1KHPA 3LXSA 5A24A 1U9VA 1AYWA 3IOQA 4ZUXU 2E01A 1TL9A 3H7DA 3IEJA 3D6SA 2FO5A 3BC3A 2ACTA 2AYNA 3NHEA 3CBJA 1Q6KA 1JQPA 1SNKA 2IBIA 4PI3A 4YV8A 6PADA 1KXRA 1AU2A 4MSXA 3B79A 1YALA 3OVZA 2AYOA 3RVXA 4KLBA 3V6EA 4CDDB 2PREA 3V6CA 3N3GA 1MEMA 2DC9A 1U9QX 4AXMA 4W5BA 2GFOA 1SP4B 4I07A 1KFUL 1TLOA 3KKUA 2O6XA 1BQIA 2PBHA 1PPDA 3C9EA 4X6HA 2PNSA 4K7CA 2Y5BA 3OF8A 3OVXA 5CHVA 2YJ8A 1VJVA 3PBHA 1CB5A 4DMXA 4BPVA 2FRAA 1MEGA 2E03A 4I04A 3H8BA 5FPWA 4CZWA 4PADA 1CS8A 2FTDA 3O0UA 1ICFA 3WXEA 1HUCB 1AIMA 4CDCB 1THEA 2FUDA 4QH6A 1PXVA 1NL6A 3BCNA 1BY8A 4W4UA 2Y6EA 1NQCA 1Y4HA 2AUZA 2ATOA 8PCHA 3HD3A 3N3KA 2DC8A 2P0RA 2R9OA 3RVVA 4N8WA 1CPJA 1X9YA 2FRQA 1ME4A 3IMAA 5CVMA 3BOWA 1AU4A 4DMYA 2G8EA 1PBHA 4X6IA 2R9FA 4FJCA 5JH3A 2C0YA 3KFQA 4HWYA 4YYWA 3IUTA 3I3TA 1U9WA 2G8JA 2BDZA 4Q8GA 3N4CA 3I06A 1PPNA 5CHTA 2F1GA 2E02A 1GECE 4OEMA 2AU1A 3U8EA 5EF4A 1QOLA 3PDFA 4BQVA 5CVNB 3K8UA 1AYUA 4WA6A 4BSQA 4G54A 4CDFB 5J94A 4YYUA 3H6SA 2NQAA 3HHAA 3MHHA 3M99A 2E00A 1CVZA 1PPOA 1QXPA 1A6RA 1DEUA 1F2BA 2AUXA 2NQDB 4YYRA 1YT7A 3BPMA 1AECA 2B1NA 5EGWA 3KWBX 5F02A 2AS8A 4MZOA 1Y08A 4YYVA 3K9MA 4MZSA 2DCCA 3BWKA 3KX1A 2G6DA 1KFXL 1YK7A 3CH2X 3P5XA 1U9XA 4FIPA 1EWMA 1IWDA 1XKGA 1FH0A 4P6GA 3BPFA 2R6NA 2YJBA 4YYSA 2YJ2A 2F7DA 3H89A 1K3BB 1NB3A 4OELA 1VSNA 3KW9A 3MTNA 1YK8A 2DC7A 2R9CA 3PW3A 2DCAA 1EF7A 4QBBA 2DCDA 4FK5A 1ITOA 2DZZA 3P5UA 3MORA 4N79A 2DJFB 1ZCMA 3LFYA 3QSDA 3HHIA 3USVA 2WBFX 1ZIVA 1O0EA 1EWOA 4CDEB 3GCBA 2JQFR 3MHSA 4BS5A 3AI8A 2HH5A 2R9NA 1PADA 4QRGA 2BDLA 1CJLA 3E1ZB 3TNXA 1STFE 2R9MA 2XU3A 2OZ2A 1PIPA 3OF9A 2XU1A 2B1MA 1BP4A 1CTEA 4X6JA 1ATKA 1GLOA 3CBKA 3IV2A 3RVWA 4BS6A 2HHNA 2P86A 2P7UA 2CIOA 1GMYA 2FQ9A 4I05A 3HWNA 3QT4A 3O1GA 1TU6A 2YJ9A 1AYVA 4PP1A 1MDWA 1YVBA 1S4VA 1ME3A 3KWZA 1NB5A
chains in the Genus database with same CATH superfamily
1QMYA 1NLJA 1F29A 1PE6A 3K24A 2FE8A 4P16A 4M0WA 4YYQA 3KSEA 2VHSA 1KHQA 1POPA 1CQDA 2BU3A 1MS6A 1EWLA 3ZUAA 4A5UA 1U5IA 4QRVA 1M6DA 1F2AA 2DZYA 2G7YA 5K16A 1GCBA 4P6EA 4MM3B 2VHFA 1PPPA 3DF0A 1F2CA 2OULA 2XU5A 3C0RA 4XUIA 9PAPA 1BGOA 1CSBB 2YJCA 4BOPA 2AVWA 3S3RA 1NPZA 2JRIA 2ARYA 1MIRA 3PNRA 2OP3A 1DF0A 2DC6A 3P5WA 4PP2E 1CV8A 2FT2A 3OISA 2HXZA 3P5VA 4BOQA 1AU3A 3WXGA 3F75A 2PADA 1EWPA 2NQGA 2DJGB 2JQGR 3S3QA 2AIMA 3IHPA 3WXFA 4YVAA 2NQIA 2AGAA 2HD5A 4N4ZA 3H8CA 4Q8HA 5CVOB 5JZEA 1PCIA 5PADA 2J7QA 4PT5A 4RY2A 3CH3X 1MHWA 2DCBA 2CB5A 4MI7A 4XR7A 3PHXA 4IP3A 3F5VA 1QDQA 3QJ3A 5JA7A 2IPPB 4OVZB 4AXLA 2BTWA 2FYEA 2H7JA 7PCKA 4D8EA 4IUMA 3ERVA 4ZTBA 2GHUA 4QRXA 1AU0A 2XU4A 4W5CA 1KHPA 3LXSA 5A24A 4BOSA 1U9VA 1AYWA 3IOQA 4ZUXU 2E01A 1TL9A 3H7DA 3IEJA 3D6SA 2FO5A 3BC3A 3PHWA 2ACTA 2AYNA 3NHEA 3CBJA 1Q6KA 1JQPA 1SNKA 4GUAA 2IBIA 4PI3A 4YV8A 6PADA 1KXRA 1AU2A 4MSXA 3B79A 3MJ5A 5E6JA 1YALA 5EZSA 3PRMA 3OVZA 3RNVA 2AYOA 3RVXA 4KLBA 3E9SA 3V6EA 4CDDB 2PREA 3V6CA 3N3GA 1MEMA 2JTCA 2DC9A 1U9QX 4AXMA 4W5BA 2GFOA 5EZQA 1SP4B 4I07A 1KFUL 1TLOA 3KKUA 2O6XA 1BQIA 4RF0A 2PBHA 1DKIA 1PPDA 3C9EA 4X6HA 2PNSA 4K7CA 2Y5BA 3OF8A 3OVXA 5CHVA 2YJ8A 1VJVA 3PBHA 1CB5A 4DMXA 3BB7A 4BPVA 2FRAA 1MEGA 2E03A 4I04A 3H8BA 5FPWA 4CZWA 4PADA 1CS8A 2FTDA 3ZNHA 3O0UA 1ICFA 3WXEA 1HUCB 1AIMA 4CDCB 3PHUA 1THEA 2FUDA 2UZJA 4QH6A 1PXVA 1NL6A 3BCNA 1BY8A 4W4UA 2Y6EA 1NQCA 4HXDB 1Y4HA 2AUZA 2ATOA 8PCHA 3HD3A 3N3KA 2DC8A 2P0RA 3TRKA 2R9OA 3RVVA 4N8WA 4D8IA 1CPJA 4XZXA 1X9YA 2FRQA 1ME4A 3IMAA 5CVMA 3BOWA 1AU4A 4DMYA 4REZA 2G8EA 1PBHA 4X6IA 2R9FA 4FJCA 5JH3A 4OW0A 2C0YA 3KFQA 1PVJA 4HWYA 4YYWA 3IUTA 3I3TA 1U9WA 2G8JA 2BDZA 4OVZA 4Q8GA 3O65A 3N4CA 3PSEA 3I06A 1PPNA 5CHTA 2F1GA 2E02A 1GECE 4OEMA 2Z84A 2AU1A 3U8EA 5EF4A 1QOLA 3PDFA 4BQVA 4WURA 5CVNB 3K8UA 1AYUA 4WA6A 4BSQA 4G54A 4CDFB 5J94A 4YYUA 3H6SA 2NQAA 3BY4A 3HHAA 3MHHA 4BOUA 3M99A 2E00A 1CVZA 1PPOA 1QXPA 1A6RA 1DEUA 5KO3A 1F2BA 2AUXA 2NQDB 4YYRA 1YT7A 3BPMA 1AECA 2B1NA 5EGWA 3KWBX 5F02A 2AS8A 4MZOA 1Y08A 3W30A 4YYVA 3K9MA 3TMPA 4MZSA 2DCCA 2DOSA 3BWKA 3KX1A 2G6DA 1KFXL 1YK7A 3CH2X 3P5XA 1U9XA 1YZBA 4FIPA 1EWMA 1IWDA 1XKGA 1FH0A 4P6GA 3BPFA 2R6NA 2YJBA 4YYSA 2YJ2A 2F7DA 3H89A 1K3BB 1NB3A 4OELA 1VSNA 3KW9A 3MTNA 4BOZA 2J7QC 1YK8A 4RF1A 2DC7A 2R9CA 3PW3A 3OQCA 2DCAA 1EF7A 4QBBA 4RKXA 2DCDA 4FK5A 1ITOA 3BBAA 2DZZA 3P5UA 3MORA 4N79A 2DJFB 3IFUA 1ZCMA 2HWKA 3LFYA 3QSDA 3HHIA 3USVA 2WBFX 1ZIVA 1O0EA 1EWOA 4CDEB 3PT2A 3GCBA 2JQFR 3MHSA 4BS5A 3AI8A 2HH5A 2R9NA 1PADA 4QRGA 2BDLA 1CJLA 3E1ZB 3TNXA 1STFE 2R9MA 2XU3A 3MP2A 2OZ2A 1UKFA 4RNAA 1PIPA 3OF9A 2XU1A 4R3DA 2B1MA 1BP4A 1CTEA 2BTWB 4X6JA 1ATKA 1GLOA 3CBKA 3IV2A 3PRPA 3RVWA 4BS6A 2HHNA 3MTVA 2P86A 2P7UA 2CIOA 1GMYA 2FQ9A 4I05A 3HWNA 3QT4A 4D8BA 3O1GA 1TU6A 2YJ9A 1AYVA 3W31A 4PP1A 1MDWA 3B21A 1YVBA 1S4VA 1ME3A 3KWZA 1NB5A
chains in the Genus database with same CATH topology
1QMYA 1NLJA 1F29A 1PE6A 2BSZA 3K24A 4YYQA 3KSEA 2VHSA 1KHQA 1POPA 1CQDA 1MS6A 1EWLA 3ZUAA 1U5IA 4QRVA 1M6DA 1F2AA 2DZYA 2VFBA 2G7YA 5K16A 1GCBA 4P6EA 2VHFA 1PPPA 3DF0A 1F2CA 2OULA 2XU5A 4XUIA 9PAPA 1BGOA 1CSBB 2YJCA 2AVWA 3S3RA 1NPZA 2ARYA 1MIRA 4NV7A 3PNRA 2OP3A 1DF0A 2DC6A 3P5WA 4PP2E 1CV8A 2FT2A 3OISA 2HXZA 3P5VA 1AU3A 3WXGA 3F75A 2PADA 1EWPA 2NQGA 2DJGB 2JQGR 3S3QA 2AIMA 3IHPA 3WXFA 4YVAA 2NQIA 2HD5A 4N4ZA 3H8CA 4Q8HA 5CVOB 1PCIA 5PADA 4RY2A 3CH3X 1MHWA 2DCBA 2CB5A 4XR7A 3F5VA 1QDQA 3QJ3A 5JA7A 2IPPB 4AXLA 2FYEA 2H7JA 7PCKA 3ERVA 2GHUA 4QRXA 1AU0A 2XU4A 4W5CA 1KHPA 3LXSA 5A24A 1U9VA 1AYWA 3IOQA 4ZUXU 2E01A 1TL9A 3H7DA 3IEJA 3D6SA 2FO5A 3BC3A 2VFCA 2ACTA 2AYNA 3NHEA 3CBJA 1Q6KA 1JQPA 1SNKA 2IBIA 4PI3A 4YV8A 6PADA 1KXRA 1AU2A 4MSXA 3B79A 4GUZA 1YALA 3OVZA 2AYOA 3RVXA 4KLBA 3V6EA 4CDDB 2PREA 3V6CA 3N3GA 1MEMA 2DC9A 1E2TA 1U9QX 4AXMA 4W5BA 2GFOA 1SP4B 4I07A 4C5PA 1KFUL 1TLOA 3KKUA 2O6XA 1BQIA 2PBHA 1PPDA 3C9EA 4X6HA 2PNSA 4K7CA 2Y5BA 3OF8A 3OVXA 5CHVA 2YJ8A 1VJVA 3PBHA 1CB5A 4DMXA 4BPVA 2FRAA 1MEGA 2E03A 4I04A 3H8BA 5FPWA 4CZWA 4PADA 1CS8A 1W6FA 2FTDA 3O0UA 1ICFA 3WXEA 1HUCB 1AIMA 4CDCB 1THEA 2FUDA 4QH6A 1PXVA 1NL6A 3BCNA 1BY8A 4W4UA 2Y6EA 1NQCA 1Y4HA 2AUZA 2ATOA 8PCHA 3HD3A 3N3KA 2DC8A 2P0RA 2R9OA 3RVVA 3LTWA 4N8WA 1CPJA 1X9YA 2FRQA 1ME4A 3IMAA 5CVMA 3BOWA 1AU4A 4DMYA 2G8EA 1PBHA 4X6IA 2R9FA 4FJCA 5JH3A 2C0YA 3KFQA 4HWYA 4YYWA 3IUTA 3I3TA 1U9WA 2G8JA 2BDZA 4Q8GA 3N4CA 3I06A 1PPNA 5CHTA 2F1GA 2E02A 1GECE 4OEMA 4B55A 2AU1A 3U8EA 5EF4A 1QOLA 3PDFA 4BQVA 5CVNB 3K8UA 1AYUA 4WA6A 4BSQA 4G54A 4CDFB 5J94A 4YYUA 3H6SA 2NQAA 3HHAA 3MHHA 3M99A 2E00A 1CVZA 1PPOA 1QXPA 1A6RA 1DEUA 1F2BA 2AUXA 2NQDB 4YYRA 1YT7A 3BPMA 1AECA 2B1NA 5EGWA 3KWBX 5F02A 2AS8A 4MZOA 1Y08A 4YYVA 3K9MA 4MZSA 1W5RA 2DCCA 3BWKA 3KX1A 2G6DA 1KFXL 1YK7A 3CH2X 3P5XA 1U9XA 4FIPA 1EWMA 1IWDA 1XKGA 1FH0A 4P6GA 3BPFA 2R6NA 2YJBA 4YYSA 2YJ2A 2F7DA 3H89A 1K3BB 1NB3A 4OELA 1VSNA 3KW9A 3MTNA 1YK8A 2DC7A 2R9CA 3PW3A 2DCAA 1EF7A 4QBBA 2DCDA 4FK5A 1ITOA 2DZZA 3P5UA 3MORA 3D9WA 4N79A 2DJFB 1ZCMA 3LFYA 3QSDA 3HHIA 3USVA 2WBFX 1ZIVA 1O0EA 1EWOA 4CDEB 3GCBA 2JQFR 3MHSA 4BS5A 3AI8A 2HH5A 2R9NA 1PADA 4QRGA 2BDLA 1CJLA 3E1ZB 3TNXA 1STFE 2R9MA 2XU3A 2OZ2A 1PIPA 3OF9A 1W4TA 2XU1A 2B1MA 1BP4A 1CTEA 4X6JA 1ATKA 1GLOA 3CBKA 3IV2A 3RVWA 4BS6A 2HHNA 2P86A 4NV8A 2P7UA 2CIOA 1GMYA 2FQ9A 4I05A 3HWNA 3QT4A 3O1GA 1TU6A 2YJ9A 1AYVA 1GX3A 4PP1A 1MDWA 4BGFA 1YVBA 1S4VA 1ME3A 3KWZA 1NB5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QMY A;  1NLJ A;  1F29 A;  1PE6 A;  3K24 A;  4YYQ A;  3KSE A;  2VHS A;  1KHQ A;  1POP A;  1CQD A;  1MS6 A;  1EWL A;  3ZUA A;  1U5I A;  4QRV A;  1M6D A;  1F2A A;  2DZY A;  2G7Y A;  5K16 A;  1GCB A;  4P6E A;  2VHF A;  1PPP A;  3DF0 A;  1F2C A;  2OUL A;  2XU5 A;  4XUI A;  9PAP A;  1BGO A;  1CSB B;  2YJC A;  2AVW A;  3S3R A;  1NPZ A;  2ARY A;  1MIR A;  3PNR A;  2OP3 A;  1DF0 A;  2DC6 A;  3P5W A;  4PP2 E;  1CV8 A;  2FT2 A;  3OIS A;  2HXZ A;  3P5V A;  1AU3 A;  3WXG A;  3F75 A;  2PAD A;  1EWP A;  2NQG A;  2DJG B;  2JQG R;  3S3Q A;  2AIM A;  3IHP A;  3WXF A;  4YVA A;  2NQI A;  2HD5 A;  4N4Z A;  3H8C A;  4Q8H A;  5CVO B;  1PCI A;  5PAD A;  4RY2 A;  3CH3 X;  1MHW A;  2DCB A;  2CB5 A;  4XR7 A;  3F5V A;  1QDQ A;  3QJ3 A;  5JA7 A;  2IPP B;  4AXL A;  2FYE A;  2H7J A;  7PCK A;  3ERV A;  2GHU A;  4QRX A;  1AU0 A;  2XU4 A;  4W5C A;  1KHP A;  3LXS A;  5A24 A;  1U9V A;  1AYW A;  3IOQ A;  4ZUX U;  2E01 A;  1TL9 A;  3H7D A;  3IEJ A;  3D6S A;  2FO5 A;  3BC3 A;  2ACT A;  2AYN A;  3NHE A;  3CBJ A;  1Q6K A;  1JQP A;  1SNK A;  2IBI A;  4PI3 A;  4YV8 A;  6PAD A;  1KXR A;  1AU2 A;  4MSX A;  3B79 A;  1YAL A;  3OVZ A;  2AYO A;  3RVX A;  4KLB A;  3V6E A;  4CDD B;  2PRE A;  3V6C A;  3N3G A;  1MEM A;  2DC9 A;  1U9Q X;  4AXM A;  4W5B A;  2GFO A;  1SP4 B;  4I07 A;  1KFU L;  1TLO A;  3KKU A;  2O6X A;  1BQI A;  2PBH A;  1PPD A;  3C9E A;  4X6H A;  2PNS A;  4K7C A;  2Y5B A;  3OF8 A;  3OVX A;  5CHV A;  2YJ8 A;  1VJV A;  3PBH A;  1CB5 A;  4DMX A;  4BPV A;  2FRA A;  1MEG A;  2E03 A;  4I04 A;  3H8B A;  5FPW A;  4CZW A;  4PAD A;  1CS8 A;  2FTD A;  3O0U A;  1ICF A;  3WXE A;  1HUC B;  1AIM A;  4CDC B;  1THE A;  2FUD A;  4QH6 A;  1PXV A;  1NL6 A;  3BCN A;  1BY8 A;  4W4U A;  2Y6E A;  1NQC A;  1Y4H A;  2AUZ A;  2ATO A;  8PCH A;  3HD3 A;  3N3K A;  2DC8 A;  2P0R A;  2R9O A;  3RVV A;  4N8W A;  1CPJ A;  1X9Y A;  2FRQ A;  1ME4 A;  3IMA A;  5CVM A;  3BOW A;  1AU4 A;  4DMY A;  2G8E A;  1PBH A;  4X6I A;  2R9F A;  4FJC A;  5JH3 A;  2C0Y A;  3KFQ A;  4HWY A;  4YYW A;  3IUT A;  3I3T A;  1U9W A;  2G8J A;  2BDZ A;  4Q8G A;  3N4C A;  3I06 A;  1PPN A;  5CHT A;  2F1G A;  2E02 A;  1GEC E;  4OEM A;  2AU1 A;  3U8E A;  5EF4 A;  1QOL A;  3PDF A;  4BQV A;  5CVN B;  3K8U A;  1AYU A;  4WA6 A;  4BSQ A;  4G54 A;  4CDF B;  5J94 A;  4YYU A;  3H6S A;  2NQA A;  3HHA A;  3MHH A;  3M99 A;  2E00 A;  1CVZ A;  1PPO A;  1QXP A;  1A6R A;  1DEU A;  1F2B A;  2AUX A;  2NQD B;  4YYR A;  1YT7 A;  3BPM A;  1AEC A;  2B1N A;  5EGW A;  3KWB X;  5F02 A;  2AS8 A;  4MZO A;  1Y08 A;  4YYV A;  3K9M A;  4MZS A;  2DCC A;  3BWK A;  3KX1 A;  2G6D A;  1KFX L;  1YK7 A;  3CH2 X;  3P5X A;  1U9X A;  4FIP A;  1EWM A;  1IWD A;  1XKG A;  1FH0 A;  4P6G A;  3BPF A;  2R6N A;  2YJB A;  4YYS A;  2YJ2 A;  2F7D A;  3H89 A;  1K3B B;  1NB3 A;  4OEL A;  1VSN A;  3KW9 A;  3MTN A;  1YK8 A;  2DC7 A;  2R9C A;  3PW3 A;  2DCA A;  1EF7 A;  4QBB A;  2DCD A;  4FK5 A;  1ITO A;  2DZZ A;  3P5U A;  3MOR A;  4N79 A;  2DJF B;  1ZCM A;  3LFY A;  3QSD A;  3HHI A;  3USV A;  2WBF X;  1ZIV A;  1O0E A;  1EWO A;  4CDE B;  3GCB A;  2JQF R;  3MHS A;  4BS5 A;  3AI8 A;  2HH5 A;  2R9N A;  1PAD A;  4QRG A;  2BDL A;  1CJL A;  3E1Z B;  3TNX A;  1STF E;  2R9M A;  2XU3 A;  2OZ2 A;  1PIP A;  3OF9 A;  2XU1 A;  2B1M A;  1BP4 A;  1CTE A;  4X6J A;  1ATK A;  1GLO A;  3CBK A;  3IV2 A;  3RVW A;  4BS6 A;  2HHN A;  2P86 A;  2P7U A;  2CIO A;  1GMY A;  2FQ9 A;  4I05 A;  3HWN A;  3QT4 A;  3O1G A;  1TU6 A;  2YJ9 A;  1AYV A;  4PP1 A;  1MDW A;  1YVB A;  1S4V A;  1ME3 A;  3KWZ A;  1NB5 A; 
#chains in the Genus database with same CATH topology
 1QMY A;  1NLJ A;  1F29 A;  1PE6 A;  3K24 A;  2FE8 A;  4P16 A;  4M0W A;  4YYQ A;  3KSE A;  2VHS A;  1KHQ A;  1POP A;  1CQD A;  2BU3 A;  1MS6 A;  1EWL A;  3ZUA A;  4A5U A;  1U5I A;  4QRV A;  1M6D A;  1F2A A;  2DZY A;  2G7Y A;  5K16 A;  1GCB A;  4P6E A;  4MM3 B;  2VHF A;  1PPP A;  3DF0 A;  1F2C A;  2OUL A;  2XU5 A;  3C0R A;  4XUI A;  9PAP A;  1BGO A;  1CSB B;  2YJC A;  4BOP A;  2AVW A;  3S3R A;  1NPZ A;  2JRI A;  2ARY A;  1MIR A;  3PNR A;  2OP3 A;  1DF0 A;  2DC6 A;  3P5W A;  4PP2 E;  1CV8 A;  2FT2 A;  3OIS A;  2HXZ A;  3P5V A;  4BOQ A;  1AU3 A;  3WXG A;  3F75 A;  2PAD A;  1EWP A;  2NQG A;  2DJG B;  2JQG R;  3S3Q A;  2AIM A;  3IHP A;  3WXF A;  4YVA A;  2NQI A;  2AGA A;  2HD5 A;  4N4Z A;  3H8C A;  4Q8H A;  5CVO B;  5JZE A;  1PCI A;  5PAD A;  2J7Q A;  4PT5 A;  4RY2 A;  3CH3 X;  1MHW A;  2DCB A;  2CB5 A;  4MI7 A;  4XR7 A;  3PHX A;  4IP3 A;  3F5V A;  1QDQ A;  3QJ3 A;  5JA7 A;  2IPP B;  4OVZ B;  4AXL A;  2BTW A;  2FYE A;  2H7J A;  7PCK A;  4D8E A;  4IUM A;  3ERV A;  4ZTB A;  2GHU A;  4QRX A;  1AU0 A;  2XU4 A;  4W5C A;  1KHP A;  3LXS A;  5A24 A;  4BOS A;  1U9V A;  1AYW A;  3IOQ A;  4ZUX U;  2E01 A;  1TL9 A;  3H7D A;  3IEJ A;  3D6S A;  2FO5 A;  3BC3 A;  3PHW A;  2ACT A;  2AYN A;  3NHE A;  3CBJ A;  1Q6K A;  1JQP A;  1SNK A;  4GUA A;  2IBI A;  4PI3 A;  4YV8 A;  6PAD A;  1KXR A;  1AU2 A;  4MSX A;  3B79 A;  3MJ5 A;  5E6J A;  1YAL A;  5EZS A;  3PRM A;  3OVZ A;  3RNV A;  2AYO A;  3RVX A;  4KLB A;  3E9S A;  3V6E A;  4CDD B;  2PRE A;  3V6C A;  3N3G A;  1MEM A;  2JTC A;  2DC9 A;  1U9Q X;  4AXM A;  4W5B A;  2GFO A;  5EZQ A;  1SP4 B;  4I07 A;  1KFU L;  1TLO A;  3KKU A;  2O6X A;  1BQI A;  4RF0 A;  2PBH A;  1DKI A;  1PPD A;  3C9E A;  4X6H A;  2PNS A;  4K7C A;  2Y5B A;  3OF8 A;  3OVX A;  5CHV A;  2YJ8 A;  1VJV A;  3PBH A;  1CB5 A;  4DMX A;  3BB7 A;  4BPV A;  2FRA A;  1MEG A;  2E03 A;  4I04 A;  3H8B A;  5FPW A;  4CZW A;  4PAD A;  1CS8 A;  2FTD A;  3ZNH A;  3O0U A;  1ICF A;  3WXE A;  1HUC B;  1AIM A;  4CDC B;  3PHU A;  1THE A;  2FUD A;  2UZJ A;  4QH6 A;  1PXV A;  1NL6 A;  3BCN A;  1BY8 A;  4W4U A;  2Y6E A;  1NQC A;  4HXD B;  1Y4H A;  2AUZ A;  2ATO A;  8PCH A;  3HD3 A;  3N3K A;  2DC8 A;  2P0R A;  3TRK A;  2R9O A;  3RVV A;  4N8W A;  4D8I A;  1CPJ A;  4XZX A;  1X9Y A;  2FRQ A;  1ME4 A;  3IMA A;  5CVM A;  3BOW A;  1AU4 A;  4DMY A;  4REZ A;  2G8E A;  1PBH A;  4X6I A;  2R9F A;  4FJC A;  5JH3 A;  4OW0 A;  2C0Y A;  3KFQ A;  1PVJ A;  4HWY A;  4YYW A;  3IUT A;  3I3T A;  1U9W A;  2G8J A;  2BDZ A;  4OVZ A;  4Q8G A;  3O65 A;  3N4C A;  3PSE A;  3I06 A;  1PPN A;  5CHT A;  2F1G A;  2E02 A;  1GEC E;  4OEM A;  2Z84 A;  2AU1 A;  3U8E A;  5EF4 A;  1QOL A;  3PDF A;  4BQV A;  4WUR A;  5CVN B;  3K8U A;  1AYU A;  4WA6 A;  4BSQ A;  4G54 A;  4CDF B;  5J94 A;  4YYU A;  3H6S A;  2NQA A;  3BY4 A;  3HHA A;  3MHH A;  4BOU A;  3M99 A;  2E00 A;  1CVZ A;  1PPO A;  1QXP A;  1A6R A;  1DEU A;  5KO3 A;  1F2B A;  2AUX A;  2NQD B;  4YYR A;  1YT7 A;  3BPM A;  1AEC A;  2B1N A;  5EGW A;  3KWB X;  5F02 A;  2AS8 A;  4MZO A;  1Y08 A;  3W30 A;  4YYV A;  3K9M A;  3TMP A;  4MZS A;  2DCC A;  2DOS A;  3BWK A;  3KX1 A;  2G6D A;  1KFX L;  1YK7 A;  3CH2 X;  3P5X A;  1U9X A;  1YZB A;  4FIP A;  1EWM A;  1IWD A;  1XKG A;  1FH0 A;  4P6G A;  3BPF A;  2R6N A;  2YJB A;  4YYS A;  2YJ2 A;  2F7D A;  3H89 A;  1K3B B;  1NB3 A;  4OEL A;  1VSN A;  3KW9 A;  3MTN A;  4BOZ A;  2J7Q C;  1YK8 A;  4RF1 A;  2DC7 A;  2R9C A;  3PW3 A;  3OQC A;  2DCA A;  1EF7 A;  4QBB A;  4RKX A;  2DCD A;  4FK5 A;  1ITO A;  3BBA A;  2DZZ A;  3P5U A;  3MOR A;  4N79 A;  2DJF B;  3IFU A;  1ZCM A;  2HWK A;  3LFY A;  3QSD A;  3HHI A;  3USV A;  2WBF X;  1ZIV A;  1O0E A;  1EWO A;  4CDE B;  3PT2 A;  3GCB A;  2JQF R;  3MHS A;  4BS5 A;  3AI8 A;  2HH5 A;  2R9N A;  1PAD A;  4QRG A;  2BDL A;  1CJL A;  3E1Z B;  3TNX A;  1STF E;  2R9M A;  2XU3 A;  3MP2 A;  2OZ2 A;  1UKF A;  4RNA A;  1PIP A;  3OF9 A;  2XU1 A;  4R3D A;  2B1M A;  1BP4 A;  1CTE A;  2BTW B;  4X6J A;  1ATK A;  1GLO A;  3CBK A;  3IV2 A;  3PRP A;  3RVW A;  4BS6 A;  2HHN A;  3MTV A;  2P86 A;  2P7U A;  2CIO A;  1GMY A;  2FQ9 A;  4I05 A;  3HWN A;  3QT4 A;  4D8B A;  3O1G A;  1TU6 A;  2YJ9 A;  1AYV A;  3W31 A;  4PP1 A;  1MDW A;  3B21 A;  1YVB A;  1S4V A;  1ME3 A;  3KWZ A;  1NB5 A; 
#chains in the Genus database with same CATH homology
 1QMY A;  1NLJ A;  1F29 A;  1PE6 A;  2BSZ A;  3K24 A;  4YYQ A;  3KSE A;  2VHS A;  1KHQ A;  1POP A;  1CQD A;  1MS6 A;  1EWL A;  3ZUA A;  1U5I A;  4QRV A;  1M6D A;  1F2A A;  2DZY A;  2VFB A;  2G7Y A;  5K16 A;  1GCB A;  4P6E A;  2VHF A;  1PPP A;  3DF0 A;  1F2C A;  2OUL A;  2XU5 A;  4XUI A;  9PAP A;  1BGO A;  1CSB B;  2YJC A;  2AVW A;  3S3R A;  1NPZ A;  2ARY A;  1MIR A;  4NV7 A;  3PNR A;  2OP3 A;  1DF0 A;  2DC6 A;  3P5W A;  4PP2 E;  1CV8 A;  2FT2 A;  3OIS A;  2HXZ A;  3P5V A;  1AU3 A;  3WXG A;  3F75 A;  2PAD A;  1EWP A;  2NQG A;  2DJG B;  2JQG R;  3S3Q A;  2AIM A;  3IHP A;  3WXF A;  4YVA A;  2NQI A;  2HD5 A;  4N4Z A;  3H8C A;  4Q8H A;  5CVO B;  1PCI A;  5PAD A;  4RY2 A;  3CH3 X;  1MHW A;  2DCB A;  2CB5 A;  4XR7 A;  3F5V A;  1QDQ A;  3QJ3 A;  5JA7 A;  2IPP B;  4AXL A;  2FYE A;  2H7J A;  7PCK A;  3ERV A;  2GHU A;  4QRX A;  1AU0 A;  2XU4 A;  4W5C A;  1KHP A;  3LXS A;  5A24 A;  1U9V A;  1AYW A;  3IOQ A;  4ZUX U;  2E01 A;  1TL9 A;  3H7D A;  3IEJ A;  3D6S A;  2FO5 A;  3BC3 A;  2VFC A;  2ACT A;  2AYN A;  3NHE A;  3CBJ A;  1Q6K A;  1JQP A;  1SNK A;  2IBI A;  4PI3 A;  4YV8 A;  6PAD A;  1KXR A;  1AU2 A;  4MSX A;  3B79 A;  4GUZ A;  1YAL A;  3OVZ A;  2AYO A;  3RVX A;  4KLB A;  3V6E A;  4CDD B;  2PRE A;  3V6C A;  3N3G A;  1MEM A;  2DC9 A;  1E2T A;  1U9Q X;  4AXM A;  4W5B A;  2GFO A;  1SP4 B;  4I07 A;  4C5P A;  1KFU L;  1TLO A;  3KKU A;  2O6X A;  1BQI A;  2PBH A;  1PPD A;  3C9E A;  4X6H A;  2PNS A;  4K7C A;  2Y5B A;  3OF8 A;  3OVX A;  5CHV A;  2YJ8 A;  1VJV A;  3PBH A;  1CB5 A;  4DMX A;  4BPV A;  2FRA A;  1MEG A;  2E03 A;  4I04 A;  3H8B A;  5FPW A;  4CZW A;  4PAD A;  1CS8 A;  1W6F A;  2FTD A;  3O0U A;  1ICF A;  3WXE A;  1HUC B;  1AIM A;  4CDC B;  1THE A;  2FUD A;  4QH6 A;  1PXV A;  1NL6 A;  3BCN A;  1BY8 A;  4W4U A;  2Y6E A;  1NQC A;  1Y4H A;  2AUZ A;  2ATO A;  8PCH A;  3HD3 A;  3N3K A;  2DC8 A;  2P0R A;  2R9O A;  3RVV A;  3LTW A;  4N8W A;  1CPJ A;  1X9Y A;  2FRQ A;  1ME4 A;  3IMA A;  5CVM A;  3BOW A;  1AU4 A;  4DMY A;  2G8E A;  1PBH A;  4X6I A;  2R9F A;  4FJC A;  5JH3 A;  2C0Y A;  3KFQ A;  4HWY A;  4YYW A;  3IUT A;  3I3T A;  1U9W A;  2G8J A;  2BDZ A;  4Q8G A;  3N4C A;  3I06 A;  1PPN A;  5CHT A;  2F1G A;  2E02 A;  1GEC E;  4OEM A;  4B55 A;  2AU1 A;  3U8E A;  5EF4 A;  1QOL A;  3PDF A;  4BQV A;  5CVN B;  3K8U A;  1AYU A;  4WA6 A;  4BSQ A;  4G54 A;  4CDF B;  5J94 A;  4YYU A;  3H6S A;  2NQA A;  3HHA A;  3MHH A;  3M99 A;  2E00 A;  1CVZ A;  1PPO A;  1QXP A;  1A6R A;  1DEU A;  1F2B A;  2AUX A;  2NQD B;  4YYR A;  1YT7 A;  3BPM A;  1AEC A;  2B1N A;  5EGW A;  3KWB X;  5F02 A;  2AS8 A;  4MZO A;  1Y08 A;  4YYV A;  3K9M A;  4MZS A;  1W5R A;  2DCC A;  3BWK A;  3KX1 A;  2G6D A;  1KFX L;  1YK7 A;  3CH2 X;  3P5X A;  1U9X A;  4FIP A;  1EWM A;  1IWD A;  1XKG A;  1FH0 A;  4P6G A;  3BPF A;  2R6N A;  2YJB A;  4YYS A;  2YJ2 A;  2F7D A;  3H89 A;  1K3B B;  1NB3 A;  4OEL A;  1VSN A;  3KW9 A;  3MTN A;  1YK8 A;  2DC7 A;  2R9C A;  3PW3 A;  2DCA A;  1EF7 A;  4QBB A;  2DCD A;  4FK5 A;  1ITO A;  2DZZ A;  3P5U A;  3MOR A;  3D9W A;  4N79 A;  2DJF B;  1ZCM A;  3LFY A;  3QSD A;  3HHI A;  3USV A;  2WBF X;  1ZIV A;  1O0E A;  1EWO A;  4CDE B;  3GCB A;  2JQF R;  3MHS A;  4BS5 A;  3AI8 A;  2HH5 A;  2R9N A;  1PAD A;  4QRG A;  2BDL A;  1CJL A;  3E1Z B;  3TNX A;  1STF E;  2R9M A;  2XU3 A;  2OZ2 A;  1PIP A;  3OF9 A;  1W4T A;  2XU1 A;  2B1M A;  1BP4 A;  1CTE A;  4X6J A;  1ATK A;  1GLO A;  3CBK A;  3IV2 A;  3RVW A;  4BS6 A;  2HHN A;  2P86 A;  4NV8 A;  2P7U A;  2CIO A;  1GMY A;  2FQ9 A;  4I05 A;  3HWN A;  3QT4 A;  3O1G A;  1TU6 A;  2YJ9 A;  1AYV A;  1GX3 A;  4PP1 A;  1MDW A;  4BGF A;  1YVB A;  1S4V A;  1ME3 A;  3KWZ A;  1NB5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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