4W5BA

Crystal structure analysis of cruzain with fragment 1 (n-(1h-benzimidazol-2-yl)-1,3-dimethyl-pyrazole-4-carboxamide)
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
215
structure length
215
Chain Sequence
APAAVDWRARGAVTAVKDQGQCGSSWAFSAIGNVECQWFLAGHPLTNLSEQMLVSCDKTDSGCSGGLMNNAFEWIVQENNGAVYTEDSYPYASGEGISPPCTTSGHTVGATITGHVELPQDEAQIAAWLAVNGPVAVAVDASSWMTYTGGVMTSCVSEQLDHGVLLVGYNDSAAVPYWIIKNSWTTQWGEEGYIRIAKGSNQCLVKEEASSAVVG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Applying Fragments Based- Drug Design to identify multiple binding modes on cysteine protease.
rcsb
molecule keywords Cruzipain
molecule tags Hydrolase/hydrolase inhibitor
source organism Trypanosoma cruzi
total genus 72
structure length 215
sequence length 215
chains with identical sequence B, C
ec nomenclature ec 3.4.22.51: Cruzipain.
pdb deposition date 2014-08-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 4w5bA00
3ZUAA 2NQGA 5JH3A 4KLBA 1AYWA 1CTEA 2O6XA 4BS6A 2HD5A 1S4VA 6PADA 3IUTA 3HHIA 3P5VA 2PREA 3OF8A 1QOLA 2AVWA 1AYVA 5JA7A 4BQVA 3RVXA 4W5CA 2XU5A 4OELA 2IPPB 5EGWA 4N79A 4YVAA 4XUIA 1CSBB 3IHPA 2AYNA 4YYUA 3BC3A 3LFYA 3V6EA 1PADA 2VHSA 1PCIA 3WXGA 1F29A 2HH5A 5J94A 1NLJA 2HHNA 2E00A 1PXVA 2PNSA 4OEMA 3K24A 2AUXA 3BPMA 1ZCMA 3K9MA 3KWZA 2GFOA 2FUDA 2H7JA 3TNXA 2FT2A 1XKGA 2B1NA 2DJFB 3WXEA 1YK8A 2DZZA 2ARYA 1GECE 3IOQA 4BPVA 3USVA 1NB3A 1EF7A 3D6SA 4Q8HA 1BP4A 4QBBA 1AU2A 4X6HA 2AS8A 3C9EA 1Y4HA 3MHSA 1MDWA 2FO5A 3H8CA 4WA6A 4FIPA 1ATKA 1EWPA 1KHQA 4YYSA 3I3TA 1AIMA 7PCKA 2IBIA 1SP4B 2AUZA 2NQAA 1YK7A 1CPJA 4PADA 2OP3A 4N8WA 1VSNA 2FTDA 1U9XA 3OVZA 2CIOA 3LXSA 1BY8A 1ITOA 4YYWA 2YJ8A 4I07A 1YVBA 2VHFA 3I06A 1O0EA 4P6EA 1CB5A 4I05A 1CV8A 3CH3X 1TU6A 3RVWA 2XU3A 2Y5BA 4PP1A 3F75A 3KWBX 1GCBA 1MHWA 4QRVA 3IV2A 1BGOA 1AU3A 2FYEA 3CBKA 2R9MA 3BOWA 3GCBA 3MTNA 4QRXA 3KSEA 3QSDA 2DCAA 2FQ9A 3U8EA 5F02A 3MHHA 2BDLA 1EWLA 1CVZA 1PPPA 2XU1A 3PDFA 2R9CA 4W5BA 2YJ9A 1PE6A 2F1GA 4PI3A 2NQDB 3BPFA 4CDFB 2DZYA 2E01A 3HHAA 1MIRA 1PPOA 4YV8A 3OF9A 4BS5A 3O0UA 3N4CA 4X6JA 4DMYA 5A24A 1U5IA 5FPWA 3HD3A 1EWOA 1SNKA 2AIMA 1DF0A 1HUCB 2CB5A 1CQDA 2YJBA 4QH6A 1THEA 2OZ2A 9PAPA 1NB5A 3CBJA 4G54A 1GLOA 1EWMA 1AU0A 1TLOA 2R9NA 4W4UA 2P86A 3QJ3A 1M6DA 2YJCA 5CHVA 2C0YA 2DC9A 3WXFA 1VJVA 4YYQA 2E03A 2DCCA 1F2BA 3K8UA 1KHPA 3PW3A 4XR7A 5CVMA 3P5WA 3H8BA 3H89A 2XU4A 1QMYA 3M99A 3BCNA 2PADA 5CHTA 3V6CA 4BSQA 1NPZA 1Y08A 4FK5A 3MORA 2F7DA 3S3QA 1CS8A 3QT4A 1POPA 2DC6A 2ATOA 4YYVA 1ME3A 2OULA 4RY2A 3E1ZB 5CVNB 2PBHA 3ERVA 1KXRA 2AU1A 4N4ZA 3PNRA 1F2AA 1K3BB 2G8EA 3H7DA 1MS6A 2Y6EA 3N3GA 4FJCA 3RVVA 3DF0A 1ME4A 3OVXA 1BQIA 4AXLA 1A6RA 1Q6KA 2DC7A 1QDQA 4AXMA 2P0RA 3IMAA 4DMXA 1AU4A 1PPDA 3PBHA 8PCHA 1PBHA 4PP2E 3KFQA 1F2CA 3BWKA 2BDZA 1MEGA 1NL6A 1QXPA 1ZIVA 1PIPA 4QRGA 2ACTA 4CDCB 2P7UA 1MEMA 2DCDA 4CDDB 2R9OA 2WBFX 3NHEA 1YALA 4Q8GA 1AYUA 3H6SA 4X6IA 5K16A 3N3KA 3B79A 4K7CA 3KW9A 2GHUA 3P5XA 2DCBA 3AI8A 3KX1A 4MSXA 1TL9A 2B1MA 1FH0A 3IEJA 4CDEB 1X9YA 4CZWA 1GMYA 1ICFA 3HWNA 4MZSA 1U9QX 1U9VA 3KKUA 2JQFR 2G6DA 3O1GA 2JQGR 2NQIA 4P6GA 4MZOA 1YT7A 1PPNA 2R6NA 2HXZA 1DEUA 2YJ2A 1NQCA 1IWDA 1JQPA 4ZUXU 4I04A 1AECA 3P5UA 2DC8A 2G8JA 2FRQA 2AYOA 2E02A 5PADA 5CVOB 1CJLA 5EF4A 2DJGB 1STFE 4YYRA 3OISA 3S3RA 2FRAA 2G7YA 2R9FA 3F5VA 4HWYA 1KFXL 3CH2X 1U9WA 1KFUL
chains in the Genus database with same CATH superfamily
3ZUAA 2NQGA 5JH3A 4KLBA 1AYWA 1CTEA 2O6XA 4RNAA 4BS6A 2HD5A 1S4VA 6PADA 3IUTA 5KO3A 3HHIA 2DOSA 2PREA 3OF8A 3P5VA 1QOLA 2AVWA 1AYVA 5JA7A 4BQVA 3RVXA 5JZEA 4W5CA 2J7QC 2XU5A 4OELA 2IPPB 5EGWA 4N79A 4YVAA 4XUIA 1CSBB 3IHPA 2HWKA 2AYNA 4YYUA 4ZTBA 3BC3A 3LFYA 3O65A 3V6EA 1PADA 2VHSA 1PCIA 3WXGA 1F29A 2HH5A 5J94A 1NLJA 2HHNA 2E00A 4BOUA 1PXVA 3OQCA 2PNSA 3MTVA 4OEMA 3K24A 2AUXA 3BPMA 1ZCMA 3K9MA 3KWZA 2GFOA 2FUDA 2H7JA 3TNXA 2FT2A 1XKGA 2B1NA 2DJFB 3WXEA 1YK8A 3PHWA 2DZZA 2ARYA 1GECE 3IOQA 3B21A 4BOPA 4BPVA 3USVA 4HXDB 1NB3A 3PHXA 1EF7A 3D6SA 4Q8HA 1BP4A 4QBBA 1AU2A 4OVZA 4X6HA 2AS8A 3C9EA 1Y4HA 3MHSA 3TMPA 1MDWA 3C0RA 2FO5A 3H8CA 4WA6A 4FIPA 1ATKA 1EWPA 3BY4A 1KHQA 4YYSA 3I3TA 2JTCA 1AIMA 5E6JA 2IBIA 1SP4B 2AUZA 7PCKA 2NQAA 1YK7A 1CPJA 4PADA 2OP3A 4N8WA 1VSNA 2FTDA 1U9XA 3OVZA 2CIOA 3LXSA 1BY8A 1ITOA 4YYWA 4BOSA 2YJ8A 4I07A 4REZA 4OW0A 1YVBA 2VHFA 3I06A 1O0EA 4P6EA 4MM3B 1CB5A 4I05A 1CV8A 3CH3X 1TU6A 3RVWA 2XU3A 2Y5BA 4PP1A 3F75A 3KWBX 1GCBA 1MHWA 4QRVA 3IV2A 1BGOA 1AU3A 2FYEA 3CBKA 2R9MA 3BOWA 1UKFA 3GCBA 3MTNA 4QRXA 4BOQA 3KSEA 3QSDA 2DCAA 2FQ9A 3U8EA 5F02A 3MHHA 2BDLA 4OVZB 4RKXA 1EWLA 1CVZA 1PPPA 2XU1A 3PDFA 2R9CA 4W5BA 2YJ9A 1PE6A 2F1GA 4PI3A 3BB7A 2J7QA 2NQDB 3BPFA 4CDFB 2DZYA 2E01A 3HHAA 1MIRA 1PPOA 4YV8A 3OF9A 1PVJA 4BS5A 3O0UA 3N4CA 4X6JA 4DMYA 5A24A 1U5IA 3MJ5A 5FPWA 3HD3A 1EWOA 1SNKA 2AIMA 1DF0A 1HUCB 2CB5A 1CQDA 2YJBA 4QH6A 1THEA 2OZ2A 9PAPA 1NB5A 3CBJA 3PRPA 4R3DA 4G54A 1GLOA 1EWMA 1AU0A 1TLOA 2R9NA 4W4UA 2P86A 3QJ3A 1M6DA 4WURA 2YJCA 5CHVA 2C0YA 2DC9A 3WXFA 3PT2A 1VJVA 4YYQA 2E03A 2DCCA 1F2BA 3K8UA 1KHPA 3PW3A 4XR7A 5CVMA 3P5WA 2JRIA 3H8BA 3RNVA 3H89A 2XU4A 1QMYA 2Z84A 3M99A 3BCNA 2PADA 3PHUA 5CHTA 2UZJA 3V6CA 4BSQA 1NPZA 1Y08A 3PSEA 4FK5A 3MORA 3MP2A 2F7DA 3TRKA 3S3QA 3ZNHA 4P16A 1CS8A 3QT4A 4XZXA 1POPA 2DC6A 2ATOA 4YYVA 1ME3A 3W31A 4IUMA 2FE8A 2OULA 4RY2A 3E1ZB 5CVNB 4M0WA 2PBHA 3ERVA 1KXRA 2AU1A 4N4ZA 3E9SA 3PNRA 1F2AA 1K3BB 2G8EA 3H7DA 1MS6A 1YZBA 2Y6EA 3N3GA 4FJCA 4D8IA 3RVVA 3DF0A 1ME4A 3OVXA 1BQIA 4AXLA 1A6RA 1Q6KA 2DC7A 2BTWA 1QDQA 4AXMA 2P0RA 3IMAA 4DMXA 4IP3A 1AU4A 1PPDA 3PBHA 8PCHA 3IFUA 5EZSA 1PBHA 4PP2E 2BU3A 3KFQA 4A5UA 1F2CA 3BWKA 3W30A 2BDZA 1MEGA 1NL6A 1QXPA 1ZIVA 1PIPA 4QRGA 2ACTA 4BOZA 4CDCB 2P7UA 1MEMA 3BBAA 2DCDA 4CDDB 2R9OA 2WBFX 3NHEA 1YALA 4Q8GA 1AYUA 3H6SA 4X6IA 5K16A 4RF1A 3N3KA 3B79A 4K7CA 3KW9A 2GHUA 3P5XA 2DCBA 3AI8A 3KX1A 4MSXA 1TL9A 2B1MA 1FH0A 3IEJA 4CDEB 1X9YA 4CZWA 1GMYA 2BTWB 1ICFA 3HWNA 4MZSA 1U9QX 1U9VA 3KKUA 2JQFR 2G6DA 3O1GA 2JQGR 4D8EA 2NQIA 4P6GA 4MZOA 1YT7A 4PT5A 1PPNA 2R6NA 5EZQA 2HXZA 1DEUA 2YJ2A 1NQCA 1IWDA 1JQPA 4ZUXU 4I04A 1AECA 3P5UA 2DC8A 2G8JA 2FRQA 2AYOA 2E02A 5PADA 5CVOB 1CJLA 3PRMA 5EF4A 2DJGB 1STFE 4YYRA 3OISA 1DKIA 3S3RA 4MI7A 4RF0A 2FRAA 2G7YA 2R9FA 3F5VA 4HWYA 1KFXL 2AGAA 3CH2X 1U9WA 1KFUL 4D8BA 4GUAA
chains in the Genus database with same CATH topology
3ZUAA 2NQGA 5JH3A 4KLBA 1AYWA 1CTEA 2O6XA 4BS6A 2HD5A 1S4VA 6PADA 3IUTA 3HHIA 1W5RA 2PREA 3OF8A 3P5VA 1QOLA 2AVWA 1AYVA 5JA7A 4BQVA 3RVXA 4W5CA 2XU5A 4OELA 2IPPB 5EGWA 4N79A 4YVAA 4XUIA 1CSBB 3IHPA 2AYNA 4YYUA 3BC3A 3LFYA 3V6EA 1PADA 2VHSA 1PCIA 3WXGA 1F29A 2HH5A 4NV8A 1W4TA 5J94A 1NLJA 2HHNA 2E00A 1PXVA 2PNSA 4OEMA 3K24A 2AUXA 3BPMA 1ZCMA 3K9MA 3KWZA 2GFOA 2FUDA 2H7JA 3TNXA 2FT2A 1XKGA 2B1NA 2DJFB 3WXEA 1YK8A 2DZZA 2ARYA 1GECE 3IOQA 4BPVA 3USVA 1NB3A 1EF7A 3D6SA 4Q8HA 1BP4A 4QBBA 1AU2A 4X6HA 2AS8A 3C9EA 1Y4HA 3MHSA 1MDWA 2FO5A 3H8CA 4WA6A 4FIPA 1ATKA 1EWPA 1KHQA 4YYSA 3I3TA 1AIMA 7PCKA 2IBIA 1SP4B 2AUZA 2NQAA 1YK7A 1CPJA 2VFBA 4PADA 2OP3A 4N8WA 1VSNA 2FTDA 1U9XA 3OVZA 2CIOA 3LXSA 1BY8A 1ITOA 4YYWA 2YJ8A 4I07A 2BSZA 1YVBA 2VHFA 3I06A 1O0EA 4P6EA 1CB5A 4I05A 1CV8A 3CH3X 1TU6A 3RVWA 2XU3A 2Y5BA 4PP1A 3F75A 3KWBX 1GCBA 1MHWA 4QRVA 3IV2A 1BGOA 1AU3A 2FYEA 3CBKA 2R9MA 3BOWA 3GCBA 3MTNA 4QRXA 3KSEA 3QSDA 2DCAA 2FQ9A 3U8EA 5F02A 3MHHA 2BDLA 1EWLA 1CVZA 1E2TA 1PPPA 2XU1A 3PDFA 2R9CA 4W5BA 2YJ9A 1PE6A 2F1GA 4PI3A 2NQDB 3BPFA 4CDFB 2DZYA 2E01A 3HHAA 1MIRA 1PPOA 4YV8A 3OF9A 4BS5A 3O0UA 3N4CA 4X6JA 4DMYA 5A24A 1U5IA 5FPWA 3HD3A 1EWOA 1SNKA 2AIMA 1DF0A 1HUCB 2CB5A 1CQDA 2YJBA 4QH6A 1THEA 2OZ2A 9PAPA 1NB5A 4NV7A 3CBJA 4G54A 1GLOA 1EWMA 1AU0A 1TLOA 4GUZA 2R9NA 4W4UA 2P86A 3QJ3A 1M6DA 1W6FA 2YJCA 5CHVA 2C0YA 2DC9A 3WXFA 2VFCA 1VJVA 4YYQA 2E03A 2DCCA 1F2BA 3K8UA 1KHPA 3PW3A 4XR7A 5CVMA 3P5WA 3H8BA 3H89A 2XU4A 1QMYA 3M99A 3BCNA 2PADA 5CHTA 3V6CA 4BSQA 1NPZA 1Y08A 4FK5A 3MORA 2F7DA 3S3QA 1CS8A 3QT4A 1POPA 2DC6A 2ATOA 4YYVA 1ME3A 2OULA 4RY2A 3E1ZB 5CVNB 2PBHA 3ERVA 1KXRA 2AU1A 4N4ZA 3PNRA 1F2AA 1K3BB 2G8EA 3H7DA 1MS6A 2Y6EA 3N3GA 4FJCA 3LTWA 3RVVA 3DF0A 1ME4A 3OVXA 1BQIA 4AXLA 1A6RA 1Q6KA 2DC7A 1QDQA 4AXMA 2P0RA 3IMAA 4DMXA 1AU4A 1PPDA 3PBHA 8PCHA 1PBHA 4PP2E 3KFQA 1F2CA 3BWKA 2BDZA 1MEGA 1NL6A 1QXPA 1ZIVA 1PIPA 4QRGA 2ACTA 4CDCB 2P7UA 1MEMA 2DCDA 4CDDB 2R9OA 2WBFX 3NHEA 1YALA 4Q8GA 1AYUA 3H6SA 4X6IA 5K16A 3N3KA 3B79A 4K7CA 3KW9A 2GHUA 3P5XA 2DCBA 3AI8A 3KX1A 4MSXA 1TL9A 2B1MA 4C5PA 1FH0A 3IEJA 4CDEB 1X9YA 4CZWA 1GMYA 3D9WA 1ICFA 3HWNA 4MZSA 1U9QX 4B55A 1U9VA 3KKUA 2JQFR 2G6DA 3O1GA 2JQGR 2NQIA 4P6GA 4MZOA 1YT7A 1PPNA 2R6NA 2HXZA 1DEUA 2YJ2A 1NQCA 1IWDA 1JQPA 4ZUXU 4I04A 1AECA 3P5UA 2DC8A 2G8JA 2FRQA 1GX3A 2AYOA 2E02A 5PADA 5CVOB 1CJLA 5EF4A 2DJGB 1STFE 4YYRA 3OISA 3S3RA 4BGFA 2FRAA 2G7YA 2R9FA 3F5VA 4HWYA 1KFXL 3CH2X 1U9WA 1KFUL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZUA A;  2NQG A;  5JH3 A;  4KLB A;  1AYW A;  1CTE A;  2O6X A;  4BS6 A;  2HD5 A;  1S4V A;  6PAD A;  3IUT A;  3HHI A;  3P5V A;  2PRE A;  3OF8 A;  1QOL A;  2AVW A;  1AYV A;  5JA7 A;  4BQV A;  3RVX A;  4W5C A;  2XU5 A;  4OEL A;  2IPP B;  5EGW A;  4N79 A;  4YVA A;  4XUI A;  1CSB B;  3IHP A;  2AYN A;  4YYU A;  3BC3 A;  3LFY A;  3V6E A;  1PAD A;  2VHS A;  1PCI A;  3WXG A;  1F29 A;  2HH5 A;  5J94 A;  1NLJ A;  2HHN A;  2E00 A;  1PXV A;  2PNS A;  4OEM A;  3K24 A;  2AUX A;  3BPM A;  1ZCM A;  3K9M A;  3KWZ A;  2GFO A;  2FUD A;  2H7J A;  3TNX A;  2FT2 A;  1XKG A;  2B1N A;  2DJF B;  3WXE A;  1YK8 A;  2DZZ A;  2ARY A;  1GEC E;  3IOQ A;  4BPV A;  3USV A;  1NB3 A;  1EF7 A;  3D6S A;  4Q8H A;  1BP4 A;  4QBB A;  1AU2 A;  4X6H A;  2AS8 A;  3C9E A;  1Y4H A;  3MHS A;  1MDW A;  2FO5 A;  3H8C A;  4WA6 A;  4FIP A;  1ATK A;  1EWP A;  1KHQ A;  4YYS A;  3I3T A;  1AIM A;  7PCK A;  2IBI A;  1SP4 B;  2AUZ A;  2NQA A;  1YK7 A;  1CPJ A;  4PAD A;  2OP3 A;  4N8W A;  1VSN A;  2FTD A;  1U9X A;  3OVZ A;  2CIO A;  3LXS A;  1BY8 A;  1ITO A;  4YYW A;  2YJ8 A;  4I07 A;  1YVB A;  2VHF A;  3I06 A;  1O0E A;  4P6E A;  1CB5 A;  4I05 A;  1CV8 A;  3CH3 X;  1TU6 A;  3RVW A;  2XU3 A;  2Y5B A;  4PP1 A;  3F75 A;  3KWB X;  1GCB A;  1MHW A;  4QRV A;  3IV2 A;  1BGO A;  1AU3 A;  2FYE A;  3CBK A;  2R9M A;  3BOW A;  3GCB A;  3MTN A;  4QRX A;  3KSE A;  3QSD A;  2DCA A;  2FQ9 A;  3U8E A;  5F02 A;  3MHH A;  2BDL A;  1EWL A;  1CVZ A;  1PPP A;  2XU1 A;  3PDF A;  2R9C A;  4W5B A;  2YJ9 A;  1PE6 A;  2F1G A;  4PI3 A;  2NQD B;  3BPF A;  4CDF B;  2DZY A;  2E01 A;  3HHA A;  1MIR A;  1PPO A;  4YV8 A;  3OF9 A;  4BS5 A;  3O0U A;  3N4C A;  4X6J A;  4DMY A;  5A24 A;  1U5I A;  5FPW A;  3HD3 A;  1EWO A;  1SNK A;  2AIM A;  1DF0 A;  1HUC B;  2CB5 A;  1CQD A;  2YJB A;  4QH6 A;  1THE A;  2OZ2 A;  9PAP A;  1NB5 A;  3CBJ A;  4G54 A;  1GLO A;  1EWM A;  1AU0 A;  1TLO A;  2R9N A;  4W4U A;  2P86 A;  3QJ3 A;  1M6D A;  2YJC A;  5CHV A;  2C0Y A;  2DC9 A;  3WXF A;  1VJV A;  4YYQ A;  2E03 A;  2DCC A;  1F2B A;  3K8U A;  1KHP A;  3PW3 A;  4XR7 A;  5CVM A;  3P5W A;  3H8B A;  3H89 A;  2XU4 A;  1QMY A;  3M99 A;  3BCN A;  2PAD A;  5CHT A;  3V6C A;  4BSQ A;  1NPZ A;  1Y08 A;  4FK5 A;  3MOR A;  2F7D A;  3S3Q A;  1CS8 A;  3QT4 A;  1POP A;  2DC6 A;  2ATO A;  4YYV A;  1ME3 A;  2OUL A;  4RY2 A;  3E1Z B;  5CVN B;  2PBH A;  3ERV A;  1KXR A;  2AU1 A;  4N4Z A;  3PNR A;  1F2A A;  1K3B B;  2G8E A;  3H7D A;  1MS6 A;  2Y6E A;  3N3G A;  4FJC A;  3RVV A;  3DF0 A;  1ME4 A;  3OVX A;  1BQI A;  4AXL A;  1A6R A;  1Q6K A;  2DC7 A;  1QDQ A;  4AXM A;  2P0R A;  3IMA A;  4DMX A;  1AU4 A;  1PPD A;  3PBH A;  8PCH A;  1PBH A;  4PP2 E;  3KFQ A;  1F2C A;  3BWK A;  2BDZ A;  1MEG A;  1NL6 A;  1QXP A;  1ZIV A;  1PIP A;  4QRG A;  2ACT A;  4CDC B;  2P7U A;  1MEM A;  2DCD A;  4CDD B;  2R9O A;  2WBF X;  3NHE A;  1YAL A;  4Q8G A;  1AYU A;  3H6S A;  4X6I A;  5K16 A;  3N3K A;  3B79 A;  4K7C A;  3KW9 A;  2GHU A;  3P5X A;  2DCB A;  3AI8 A;  3KX1 A;  4MSX A;  1TL9 A;  2B1M A;  1FH0 A;  3IEJ A;  4CDE B;  1X9Y A;  4CZW A;  1GMY A;  1ICF A;  3HWN A;  4MZS A;  1U9Q X;  1U9V A;  3KKU A;  2JQF R;  2G6D A;  3O1G A;  2JQG R;  2NQI A;  4P6G A;  4MZO A;  1YT7 A;  1PPN A;  2R6N A;  2HXZ A;  1DEU A;  2YJ2 A;  1NQC A;  1IWD A;  1JQP A;  4ZUX U;  4I04 A;  1AEC A;  3P5U A;  2DC8 A;  2G8J A;  2FRQ A;  2AYO A;  2E02 A;  5PAD A;  5CVO B;  1CJL A;  5EF4 A;  2DJG B;  1STF E;  4YYR A;  3OIS A;  3S3R A;  2FRA A;  2G7Y A;  2R9F A;  3F5V A;  4HWY A;  1KFX L;  3CH2 X;  1U9W A;  1KFU L; 
#chains in the Genus database with same CATH topology
 3ZUA A;  2NQG A;  5JH3 A;  4KLB A;  1AYW A;  1CTE A;  2O6X A;  4RNA A;  4BS6 A;  2HD5 A;  1S4V A;  6PAD A;  3IUT A;  5KO3 A;  3HHI A;  2DOS A;  2PRE A;  3OF8 A;  3P5V A;  1QOL A;  2AVW A;  1AYV A;  5JA7 A;  4BQV A;  3RVX A;  5JZE A;  4W5C A;  2J7Q C;  2XU5 A;  4OEL A;  2IPP B;  5EGW A;  4N79 A;  4YVA A;  4XUI A;  1CSB B;  3IHP A;  2HWK A;  2AYN A;  4YYU A;  4ZTB A;  3BC3 A;  3LFY A;  3O65 A;  3V6E A;  1PAD A;  2VHS A;  1PCI A;  3WXG A;  1F29 A;  2HH5 A;  5J94 A;  1NLJ A;  2HHN A;  2E00 A;  4BOU A;  1PXV A;  3OQC A;  2PNS A;  3MTV A;  4OEM A;  3K24 A;  2AUX A;  3BPM A;  1ZCM A;  3K9M A;  3KWZ A;  2GFO A;  2FUD A;  2H7J A;  3TNX A;  2FT2 A;  1XKG A;  2B1N A;  2DJF B;  3WXE A;  1YK8 A;  3PHW A;  2DZZ A;  2ARY A;  1GEC E;  3IOQ A;  3B21 A;  4BOP A;  4BPV A;  3USV A;  4HXD B;  1NB3 A;  3PHX A;  1EF7 A;  3D6S A;  4Q8H A;  1BP4 A;  4QBB A;  1AU2 A;  4OVZ A;  4X6H A;  2AS8 A;  3C9E A;  1Y4H A;  3MHS A;  3TMP A;  1MDW A;  3C0R A;  2FO5 A;  3H8C A;  4WA6 A;  4FIP A;  1ATK A;  1EWP A;  3BY4 A;  1KHQ A;  4YYS A;  3I3T A;  2JTC A;  1AIM A;  5E6J A;  2IBI A;  1SP4 B;  2AUZ A;  7PCK A;  2NQA A;  1YK7 A;  1CPJ A;  4PAD A;  2OP3 A;  4N8W A;  1VSN A;  2FTD A;  1U9X A;  3OVZ A;  2CIO A;  3LXS A;  1BY8 A;  1ITO A;  4YYW A;  4BOS A;  2YJ8 A;  4I07 A;  4REZ A;  4OW0 A;  1YVB A;  2VHF A;  3I06 A;  1O0E A;  4P6E A;  4MM3 B;  1CB5 A;  4I05 A;  1CV8 A;  3CH3 X;  1TU6 A;  3RVW A;  2XU3 A;  2Y5B A;  4PP1 A;  3F75 A;  3KWB X;  1GCB A;  1MHW A;  4QRV A;  3IV2 A;  1BGO A;  1AU3 A;  2FYE A;  3CBK A;  2R9M A;  3BOW A;  1UKF A;  3GCB A;  3MTN A;  4QRX A;  4BOQ A;  3KSE A;  3QSD A;  2DCA A;  2FQ9 A;  3U8E A;  5F02 A;  3MHH A;  2BDL A;  4OVZ B;  4RKX A;  1EWL A;  1CVZ A;  1PPP A;  2XU1 A;  3PDF A;  2R9C A;  4W5B A;  2YJ9 A;  1PE6 A;  2F1G A;  4PI3 A;  3BB7 A;  2J7Q A;  2NQD B;  3BPF A;  4CDF B;  2DZY A;  2E01 A;  3HHA A;  1MIR A;  1PPO A;  4YV8 A;  3OF9 A;  1PVJ A;  4BS5 A;  3O0U A;  3N4C A;  4X6J A;  4DMY A;  5A24 A;  1U5I A;  3MJ5 A;  5FPW A;  3HD3 A;  1EWO A;  1SNK A;  2AIM A;  1DF0 A;  1HUC B;  2CB5 A;  1CQD A;  2YJB A;  4QH6 A;  1THE A;  2OZ2 A;  9PAP A;  1NB5 A;  3CBJ A;  3PRP A;  4R3D A;  4G54 A;  1GLO A;  1EWM A;  1AU0 A;  1TLO A;  2R9N A;  4W4U A;  2P86 A;  3QJ3 A;  1M6D A;  4WUR A;  2YJC A;  5CHV A;  2C0Y A;  2DC9 A;  3WXF A;  3PT2 A;  1VJV A;  4YYQ A;  2E03 A;  2DCC A;  1F2B A;  3K8U A;  1KHP A;  3PW3 A;  4XR7 A;  5CVM A;  3P5W A;  2JRI A;  3H8B A;  3RNV A;  3H89 A;  2XU4 A;  1QMY A;  2Z84 A;  3M99 A;  3BCN A;  2PAD A;  3PHU A;  5CHT A;  2UZJ A;  3V6C A;  4BSQ A;  1NPZ A;  1Y08 A;  3PSE A;  4FK5 A;  3MOR A;  3MP2 A;  2F7D A;  3TRK A;  3S3Q A;  3ZNH A;  4P16 A;  1CS8 A;  3QT4 A;  4XZX A;  1POP A;  2DC6 A;  2ATO A;  4YYV A;  1ME3 A;  3W31 A;  4IUM A;  2FE8 A;  2OUL A;  4RY2 A;  3E1Z B;  5CVN B;  4M0W A;  2PBH A;  3ERV A;  1KXR A;  2AU1 A;  4N4Z A;  3E9S A;  3PNR A;  1F2A A;  1K3B B;  2G8E A;  3H7D A;  1MS6 A;  1YZB A;  2Y6E A;  3N3G A;  4FJC A;  4D8I A;  3RVV A;  3DF0 A;  1ME4 A;  3OVX A;  1BQI A;  4AXL A;  1A6R A;  1Q6K A;  2DC7 A;  2BTW A;  1QDQ A;  4AXM A;  2P0R A;  3IMA A;  4DMX A;  4IP3 A;  1AU4 A;  1PPD A;  3PBH A;  8PCH A;  3IFU A;  5EZS A;  1PBH A;  4PP2 E;  2BU3 A;  3KFQ A;  4A5U A;  1F2C A;  3BWK A;  3W30 A;  2BDZ A;  1MEG A;  1NL6 A;  1QXP A;  1ZIV A;  1PIP A;  4QRG A;  2ACT A;  4BOZ A;  4CDC B;  2P7U A;  1MEM A;  3BBA A;  2DCD A;  4CDD B;  2R9O A;  2WBF X;  3NHE A;  1YAL A;  4Q8G A;  1AYU A;  3H6S A;  4X6I A;  5K16 A;  4RF1 A;  3N3K A;  3B79 A;  4K7C A;  3KW9 A;  2GHU A;  3P5X A;  2DCB A;  3AI8 A;  3KX1 A;  4MSX A;  1TL9 A;  2B1M A;  1FH0 A;  3IEJ A;  4CDE B;  1X9Y A;  4CZW A;  1GMY A;  2BTW B;  1ICF A;  3HWN A;  4MZS A;  1U9Q X;  1U9V A;  3KKU A;  2JQF R;  2G6D A;  3O1G A;  2JQG R;  4D8E A;  2NQI A;  4P6G A;  4MZO A;  1YT7 A;  4PT5 A;  1PPN A;  2R6N A;  5EZQ A;  2HXZ A;  1DEU A;  2YJ2 A;  1NQC A;  1IWD A;  1JQP A;  4ZUX U;  4I04 A;  1AEC A;  3P5U A;  2DC8 A;  2G8J A;  2FRQ A;  2AYO A;  2E02 A;  5PAD A;  5CVO B;  1CJL A;  3PRM A;  5EF4 A;  2DJG B;  1STF E;  4YYR A;  3OIS A;  1DKI A;  3S3R A;  4MI7 A;  4RF0 A;  2FRA A;  2G7Y A;  2R9F A;  3F5V A;  4HWY A;  1KFX L;  2AGA A;  3CH2 X;  1U9W A;  1KFU L;  4D8B A;  4GUA A; 
#chains in the Genus database with same CATH homology
 3ZUA A;  2NQG A;  5JH3 A;  4KLB A;  1AYW A;  1CTE A;  2O6X A;  4BS6 A;  2HD5 A;  1S4V A;  6PAD A;  3IUT A;  3HHI A;  1W5R A;  2PRE A;  3OF8 A;  3P5V A;  1QOL A;  2AVW A;  1AYV A;  5JA7 A;  4BQV A;  3RVX A;  4W5C A;  2XU5 A;  4OEL A;  2IPP B;  5EGW A;  4N79 A;  4YVA A;  4XUI A;  1CSB B;  3IHP A;  2AYN A;  4YYU A;  3BC3 A;  3LFY A;  3V6E A;  1PAD A;  2VHS A;  1PCI A;  3WXG A;  1F29 A;  2HH5 A;  4NV8 A;  1W4T A;  5J94 A;  1NLJ A;  2HHN A;  2E00 A;  1PXV A;  2PNS A;  4OEM A;  3K24 A;  2AUX A;  3BPM A;  1ZCM A;  3K9M A;  3KWZ A;  2GFO A;  2FUD A;  2H7J A;  3TNX A;  2FT2 A;  1XKG A;  2B1N A;  2DJF B;  3WXE A;  1YK8 A;  2DZZ A;  2ARY A;  1GEC E;  3IOQ A;  4BPV A;  3USV A;  1NB3 A;  1EF7 A;  3D6S A;  4Q8H A;  1BP4 A;  4QBB A;  1AU2 A;  4X6H A;  2AS8 A;  3C9E A;  1Y4H A;  3MHS A;  1MDW A;  2FO5 A;  3H8C A;  4WA6 A;  4FIP A;  1ATK A;  1EWP A;  1KHQ A;  4YYS A;  3I3T A;  1AIM A;  7PCK A;  2IBI A;  1SP4 B;  2AUZ A;  2NQA A;  1YK7 A;  1CPJ A;  2VFB A;  4PAD A;  2OP3 A;  4N8W A;  1VSN A;  2FTD A;  1U9X A;  3OVZ A;  2CIO A;  3LXS A;  1BY8 A;  1ITO A;  4YYW A;  2YJ8 A;  4I07 A;  2BSZ A;  1YVB A;  2VHF A;  3I06 A;  1O0E A;  4P6E A;  1CB5 A;  4I05 A;  1CV8 A;  3CH3 X;  1TU6 A;  3RVW A;  2XU3 A;  2Y5B A;  4PP1 A;  3F75 A;  3KWB X;  1GCB A;  1MHW A;  4QRV A;  3IV2 A;  1BGO A;  1AU3 A;  2FYE A;  3CBK A;  2R9M A;  3BOW A;  3GCB A;  3MTN A;  4QRX A;  3KSE A;  3QSD A;  2DCA A;  2FQ9 A;  3U8E A;  5F02 A;  3MHH A;  2BDL A;  1EWL A;  1CVZ A;  1E2T A;  1PPP A;  2XU1 A;  3PDF A;  2R9C A;  4W5B A;  2YJ9 A;  1PE6 A;  2F1G A;  4PI3 A;  2NQD B;  3BPF A;  4CDF B;  2DZY A;  2E01 A;  3HHA A;  1MIR A;  1PPO A;  4YV8 A;  3OF9 A;  4BS5 A;  3O0U A;  3N4C A;  4X6J A;  4DMY A;  5A24 A;  1U5I A;  5FPW A;  3HD3 A;  1EWO A;  1SNK A;  2AIM A;  1DF0 A;  1HUC B;  2CB5 A;  1CQD A;  2YJB A;  4QH6 A;  1THE A;  2OZ2 A;  9PAP A;  1NB5 A;  4NV7 A;  3CBJ A;  4G54 A;  1GLO A;  1EWM A;  1AU0 A;  1TLO A;  4GUZ A;  2R9N A;  4W4U A;  2P86 A;  3QJ3 A;  1M6D A;  1W6F A;  2YJC A;  5CHV A;  2C0Y A;  2DC9 A;  3WXF A;  2VFC A;  1VJV A;  4YYQ A;  2E03 A;  2DCC A;  1F2B A;  3K8U A;  1KHP A;  3PW3 A;  4XR7 A;  5CVM A;  3P5W A;  3H8B A;  3H89 A;  2XU4 A;  1QMY A;  3M99 A;  3BCN A;  2PAD A;  5CHT A;  3V6C A;  4BSQ A;  1NPZ A;  1Y08 A;  4FK5 A;  3MOR A;  2F7D A;  3S3Q A;  1CS8 A;  3QT4 A;  1POP A;  2DC6 A;  2ATO A;  4YYV A;  1ME3 A;  2OUL A;  4RY2 A;  3E1Z B;  5CVN B;  2PBH A;  3ERV A;  1KXR A;  2AU1 A;  4N4Z A;  3PNR A;  1F2A A;  1K3B B;  2G8E A;  3H7D A;  1MS6 A;  2Y6E A;  3N3G A;  4FJC A;  3LTW A;  3RVV A;  3DF0 A;  1ME4 A;  3OVX A;  1BQI A;  4AXL A;  1A6R A;  1Q6K A;  2DC7 A;  1QDQ A;  4AXM A;  2P0R A;  3IMA A;  4DMX A;  1AU4 A;  1PPD A;  3PBH A;  8PCH A;  1PBH A;  4PP2 E;  3KFQ A;  1F2C A;  3BWK A;  2BDZ A;  1MEG A;  1NL6 A;  1QXP A;  1ZIV A;  1PIP A;  4QRG A;  2ACT A;  4CDC B;  2P7U A;  1MEM A;  2DCD A;  4CDD B;  2R9O A;  2WBF X;  3NHE A;  1YAL A;  4Q8G A;  1AYU A;  3H6S A;  4X6I A;  5K16 A;  3N3K A;  3B79 A;  4K7C A;  3KW9 A;  2GHU A;  3P5X A;  2DCB A;  3AI8 A;  3KX1 A;  4MSX A;  1TL9 A;  2B1M A;  4C5P A;  1FH0 A;  3IEJ A;  4CDE B;  1X9Y A;  4CZW A;  1GMY A;  3D9W A;  1ICF A;  3HWN A;  4MZS A;  1U9Q X;  4B55 A;  1U9V A;  3KKU A;  2JQF R;  2G6D A;  3O1G A;  2JQG R;  2NQI A;  4P6G A;  4MZO A;  1YT7 A;  1PPN A;  2R6N A;  2HXZ A;  1DEU A;  2YJ2 A;  1NQC A;  1IWD A;  1JQP A;  4ZUX U;  4I04 A;  1AEC A;  3P5U A;  2DC8 A;  2G8J A;  2FRQ A;  1GX3 A;  2AYO A;  2E02 A;  5PAD A;  5CVO B;  1CJL A;  5EF4 A;  2DJG B;  1STF E;  4YYR A;  3OIS A;  3S3R A;  4BGF A;  2FRA A;  2G7Y A;  2R9F A;  3F5V A;  4HWY A;  1KFX L;  3CH2 X;  1U9W A;  1KFU L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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