2G8EA

Calpain 1 proteolytic core in complex with snj-1715, a cyclic hemiacetal-type inhibitor
Total Genus 100
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
326
structure length
326
Chain Sequence
NAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICNLTPDLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Calpain Inhibition by alpha-Ketoamide and Cyclic Hemiacetal Inhibitors Revealed by X-ray Crystallography
pubmed doi rcsb
source organism Rattus norvegicus
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Calpain-1 catalytic subunit
total genus 100
structure length 326
sequence length 326
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2006-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2g8eA02
1U5IA 2GFOA 3TNXA 1THEA 2R9CA 5CVMA 2AS8A 3QJ3A 3LXSA 1NQCA 3H8BA 3F5VA 1EF7A 2F1GA 2YJ9A 2AYOA 4YVAA 4QH6A 4W5CA 2FTDA 1GECE 1MS6A 2FT2A 7PCKA 2G8EA 1PIPA 4YYSA 1CQDA 1M6DA 2DC8A 4N4ZA 1AIMA 1AU3A 2DCDA 1PPDA 3MTNA 2AUXA 4RY2A 2E02A 1GLOA 4FJCA 3U8EA 5CHVA 5FPWA 4YYVA 2HHNA 4Q8GA 2YJCA 1TU6A 2PADA 4OELA 1VJVA 4AXMA 1F2CA 1AU2A 3OF9A 2PNSA 1AYUA 4QRVA 1S4VA 2ATOA 1CS8A 2P7UA 3D6SA 5F02A 3KWBX 3P5UA 3O0UA 3BPMA 3BC3A 4ZUXU 2FRAA 2B1NA 2AUZA 1CSBB 3RVXA 4QRGA 4MSXA 1MHWA 1CTEA 5J94A 2BDLA 2XU3A 2AVWA 1PE6A 1KXRA 1QMYA 3DF0A 3P5VA 2R9OA 4FK5A 1ICFA 1XKGA 1Y08A 2DZZA 1U9XA 1AU4A 1ME4A 3IUTA 2JQGR 4CDFB 1ATKA 1NPZA 5A24A 4I07A 1GMYA 2HXZA 5CHTA 5JH3A 3MHHA 1EWPA 2G8JA 2DZYA 3BWKA 3CH2X 3GCBA 1PADA 4I05A 3BPFA 3K9MA 3IHPA 4FIPA 1ZIVA 4G54A 1DF0A 4MZSA 2FYEA 1PBHA 4I04A 3HWNA 3C9EA 1NL6A 1YT7A 3V6EA 3PW3A 2PBHA 3QSDA 3I06A 2NQDB 2YJBA 3OVZA 5K16A 4PP1A 3OF8A 3OISA 4OEMA 3KX1A 4QRXA 1X9YA 2GHUA 3S3RA 2FRQA 3IEJA 1TLOA 3IMAA 2NQGA 3KFQA 1KHQA 1EWLA 3RVWA 5JA7A 2Y5BA 1PPNA 3NHEA 1PPPA 3KKUA 3KW9A 2R6NA 4K7CA 1Q6KA 1YVBA 4CDCB 3KWZA 4YYWA 1BQIA 1AU0A 4CDEB 2P86A 2R9FA 4DMXA 2DCCA 1BP4A 1CV8A 1DEUA 1F29A 1NB5A 4W4UA 5CVNB 4PADA 3WXGA 6PADA 9PAPA 5CVOB 4P6EA 3P5WA 2G7YA 3IOQA 2FUDA 3KSEA 2DC7A 1GCBA 1NB3A 2P0RA 3USVA 2R9MA 1VSNA 3K24A 3N4CA 4X6JA 2ACTA 2E00A 8PCHA 3PDFA 3B79A 3CBKA 4HWYA 2YJ8A 1CVZA 2E03A 2WBFX 1MEGA 3LFYA 2DJGB 1KFUL 2G6DA 3N3KA 2VHFA 4WA6A 4X6HA 3I3TA 3CBJA 1FH0A 3P5XA 3HHAA 2VHSA 1U9QX 2FO5A 3H6SA 1MIRA 2XU5A 3S3QA 1KFXL 1AYVA 3WXFA 3QT4A 2F7DA 4BSQA 5PADA 2IPPB 4DMYA 3PNRA 1F2BA 1YK7A 5EF4A 2XU1A 1YK8A 1POPA 1JQPA 1K3BB 1KHPA 3H7DA 3RVVA 1AECA 1AYWA 4PP2E 3MHSA 1CB5A 4KLBA 1ZCMA 3HHIA 4X6IA 2BDZA 2AYNA 1PCIA 1MEMA 3BOWA 1QOLA 2C0YA 1BGOA 3WXEA 1STFE 2DCAA 2AU1A 2DCBA 2Y6EA 1TL9A 4N79A 3H8CA 4XR7A 4YV8A 1O0EA 1Y4HA 4N8WA 4BS6A 2CIOA 4XUIA 4CDDB 4YYUA 2OULA 2HH5A 3MORA 4QBBA 4MZOA 2FQ9A 3N3GA 2XU4A 2YJ2A 2ARYA 1MDWA 1U9VA 1HUCB 3OVXA 2IBIA 1PPOA 2OZ2A 1CPJA 1SNKA 3H89A 2CB5A 3O1GA 3AI8A 2DC9A 1A6RA 3K8UA 1QDQA 4W5BA 2JQFR 4AXLA 4BPVA 2PREA 1BY8A 3M99A 2NQIA 3IV2A 1F2AA 2R9NA 1ME3A 3ERVA 4Q8HA 2NQAA 1U9WA 3BCNA 3V6CA 4YYQA 3PBHA 1QXPA 2HD5A 1CJLA 1IWDA 3HD3A 1EWMA 1YALA 2B1MA 4P6GA 1ITOA 4BQVA 1NLJA 4BS5A 4PI3A 3ZUAA 3CH3X 4CZWA 3E1ZB 2E01A 2AIMA 4YYRA 3F75A 1PXVA 2DJFB 2DC6A 2H7JA 1EWOA 2OP3A 5EGWA 2O6XA 1SP4B
chains in the Genus database with same CATH superfamily
1U5IA 2GFOA 3TNXA 1THEA 4BOPA 2R9CA 5CVMA 2AS8A 3QJ3A 3LXSA 3W30A 1NQCA 3H8BA 3F5VA 4D8EA 1EF7A 2F1GA 2YJ9A 2AYOA 4YVAA 4QH6A 4WURA 3BY4A 2FTDA 4W5CA 1GECE 1MS6A 2FT2A 7PCKA 2G8EA 4HXDB 1PIPA 4YYSA 1CQDA 1M6DA 2DC8A 4D8IA 4N4ZA 1AIMA 1AU3A 2DCDA 1PPDA 5EZSA 2J7QC 3MTNA 2AUXA 4RY2A 3O65A 2E02A 1GLOA 4FJCA 3U8EA 3PHXA 5CHVA 5FPWA 4YYVA 2HHNA 4Q8GA 2YJCA 1TU6A 2PADA 4OELA 1VJVA 4AXMA 1F2CA 1AU2A 3OF9A 2PNSA 4IUMA 4PT5A 1AYUA 4QRVA 1S4VA 3TRKA 2ATOA 1CS8A 2P7UA 3MP2A 3D6SA 1PVJA 5F02A 3KWBX 4BOZA 3P5UA 3O0UA 3BPMA 4GUAA 3BC3A 4ZUXU 2FRAA 2B1NA 2AUZA 3MJ5A 1CSBB 3RVXA 2JTCA 4QRGA 4MSXA 1MHWA 1CTEA 5J94A 2BDLA 4A5UA 2XU3A 3BB7A 4OW0A 2AVWA 1PE6A 1KXRA 1QMYA 3DF0A 2FE8A 3PT2A 3P5VA 2R9OA 3MTVA 4FK5A 1ICFA 1XKGA 3TMPA 1Y08A 2DZZA 1U9XA 1AU4A 1ME4A 3IUTA 2JQGR 4CDFB 1ATKA 1NPZA 5A24A 4I07A 4M0WA 1GMYA 2HXZA 5CHTA 5JH3A 3MHHA 1EWPA 2G8JA 2DZYA 3BWKA 3CH2X 2HWKA 3GCBA 1PADA 1DKIA 4I05A 3BPFA 3K9MA 2AGAA 3IHPA 4FIPA 1ZIVA 4G54A 1DF0A 4MZSA 2FYEA 1PBHA 4I04A 4REZA 3HWNA 3C9EA 1NL6A 1YT7A 3PHWA 3V6EA 3PW3A 2PBHA 3QSDA 2BTWB 3I06A 2NQDB 2YJBA 3OVZA 5K16A 4PP1A 3OF8A 3OISA 4OEMA 3KX1A 4QRXA 1X9YA 2GHUA 3S3RA 2FRQA 3IEJA 1TLOA 3IMAA 2NQGA 3KFQA 1KHQA 4OVZB 1EWLA 5E6JA 3RVWA 5JA7A 2Y5BA 1PPNA 3E9SA 3NHEA 1PPPA 3KKUA 3KW9A 4BOSA 2R6NA 4RF1A 4K7CA 1Q6KA 1YVBA 4CDCB 3KWZA 4YYWA 1YZBA 4ZTBA 1BQIA 1AU0A 4CDEB 2P86A 2R9FA 4DMXA 2DCCA 1BP4A 1CV8A 1DEUA 1F29A 1NB5A 4W4UA 5CVNB 4PADA 3WXGA 6PADA 9PAPA 5CVOB 4P6EA 3P5WA 2G7YA 3IOQA 3PHUA 4BOQA 2FUDA 3KSEA 2DC7A 1GCBA 1NB3A 2P0RA 4MM3B 3B21A 3C0RA 4OVZA 3USVA 2R9MA 1VSNA 3K24A 3N4CA 4X6JA 2ACTA 4RF0A 3ZNHA 2E00A 8PCHA 3PDFA 5JZEA 3B79A 3PRPA 3CBKA 4HWYA 2YJ8A 1CVZA 2E03A 2WBFX 1MEGA 3LFYA 5EZQA 2DJGB 4XZXA 1KFUL 2G6DA 3N3KA 2VHFA 4WA6A 4IP3A 4X6HA 3I3TA 3CBJA 1FH0A 3P5XA 4R3DA 3HHAA 2VHSA 1U9QX 2FO5A 3H6SA 1MIRA 3PSEA 2XU5A 3S3QA 1KFXL 1AYVA 3BBAA 3WXFA 3QT4A 2F7DA 4BSQA 5PADA 2IPPB 2J7QA 4DMYA 3PNRA 1F2BA 3OQCA 1YK7A 5EF4A 2XU1A 1YK8A 1POPA 1JQPA 1K3BB 1KHPA 2BTWA 4RNAA 3H7DA 3RVVA 1AECA 1AYWA 4PP2E 2BU3A 3RNVA 3MHSA 1CB5A 4KLBA 1ZCMA 4BOUA 3HHIA 4X6IA 2BDZA 2AYNA 1PCIA 1MEMA 3BOWA 1QOLA 2C0YA 4D8BA 1BGOA 4MI7A 3PRMA 3WXEA 1STFE 2DCAA 2AU1A 5KO3A 2DCBA 2Y6EA 2DOSA 1TL9A 4N79A 3H8CA 4XR7A 3W31A 4YV8A 1O0EA 1Y4HA 4N8WA 4BS6A 2CIOA 4XUIA 4CDDB 4YYUA 2OULA 2HH5A 3MORA 4QBBA 4MZOA 4P16A 2FQ9A 3N3GA 2XU4A 2YJ2A 2ARYA 1MDWA 1U9VA 1HUCB 3OVXA 2IBIA 1PPOA 2OZ2A 4RKXA 1CPJA 1SNKA 3H89A 2CB5A 3O1GA 3AI8A 2DC9A 1A6RA 3K8UA 1QDQA 4W5BA 2JQFR 4AXLA 2UZJA 4BPVA 2PREA 1BY8A 3M99A 2NQIA 2JRIA 3IV2A 1F2AA 2R9NA 1ME3A 1UKFA 3ERVA 4Q8HA 2NQAA 1U9WA 3BCNA 3V6CA 4YYQA 3PBHA 1QXPA 2HD5A 1CJLA 1IWDA 3HD3A 1EWMA 1YALA 2B1MA 4P6GA 1ITOA 4BQVA 1NLJA 4BS5A 4PI3A 3ZUAA 3CH3X 4CZWA 3E1ZB 3IFUA 2Z84A 2E01A 2AIMA 4YYRA 3F75A 1PXVA 2DJFB 2DC6A 2H7JA 1EWOA 2OP3A 5EGWA 2O6XA 1SP4B
chains in the Genus database with same CATH topology
1U5IA 2GFOA 3TNXA 1THEA 2R9CA 5CVMA 2AS8A 3QJ3A 3LXSA 1NQCA 3H8BA 3F5VA 1EF7A 2F1GA 2YJ9A 2AYOA 4YVAA 4QH6A 4W5CA 2FTDA 1GECE 1MS6A 2FT2A 7PCKA 2G8EA 1PIPA 4YYSA 1CQDA 1M6DA 2DC8A 4N4ZA 1AIMA 1AU3A 2DCDA 1PPDA 3MTNA 2AUXA 4RY2A 2E02A 1GLOA 4FJCA 3U8EA 5CHVA 5FPWA 4YYVA 2HHNA 4Q8GA 2YJCA 1TU6A 2PADA 4OELA 1VJVA 4AXMA 1F2CA 1AU2A 3OF9A 2PNSA 1AYUA 4QRVA 1S4VA 2ATOA 1CS8A 2P7UA 3D6SA 5F02A 3KWBX 3P5UA 3O0UA 3BPMA 3BC3A 4ZUXU 2FRAA 2B1NA 2AUZA 1CSBB 3RVXA 4QRGA 4MSXA 1MHWA 1CTEA 5J94A 2BDLA 2XU3A 2AVWA 1PE6A 1KXRA 1QMYA 3DF0A 3P5VA 2R9OA 4FK5A 1ICFA 1XKGA 1Y08A 2DZZA 1U9XA 1AU4A 1ME4A 3IUTA 2JQGR 4CDFB 1ATKA 1NPZA 5A24A 4I07A 1GMYA 2HXZA 5CHTA 5JH3A 3MHHA 1EWPA 2G8JA 2DZYA 3BWKA 3CH2X 3GCBA 1PADA 4I05A 3BPFA 3K9MA 3IHPA 4FIPA 1ZIVA 4G54A 1DF0A 4MZSA 2FYEA 1PBHA 4I04A 3HWNA 3C9EA 1NL6A 1YT7A 3V6EA 3PW3A 2PBHA 3QSDA 3I06A 2NQDB 2YJBA 3OVZA 5K16A 4PP1A 3OF8A 3OISA 4OEMA 3KX1A 4QRXA 1X9YA 2GHUA 3S3RA 2FRQA 3IEJA 1TLOA 3IMAA 2NQGA 3KFQA 1KHQA 1EWLA 3RVWA 5JA7A 1E2TA 2Y5BA 1PPNA 3NHEA 1PPPA 3KKUA 3KW9A 2R6NA 4K7CA 2BSZA 1Q6KA 1YVBA 4CDCB 3KWZA 4YYWA 1BQIA 1AU0A 4CDEB 2P86A 2R9FA 4DMXA 2DCCA 1BP4A 1CV8A 1DEUA 1F29A 1NB5A 4W4UA 5CVNB 4PADA 3WXGA 6PADA 9PAPA 4GUZA 5CVOB 4P6EA 3P5WA 2G7YA 3IOQA 3D9WA 4NV7A 2FUDA 3KSEA 2DC7A 1GCBA 1NB3A 2P0RA 3USVA 2R9MA 1VSNA 3K24A 3N4CA 4X6JA 2ACTA 4C5PA 2E00A 8PCHA 3PDFA 3B79A 3CBKA 4B55A 4HWYA 4BGFA 2YJ8A 1CVZA 2E03A 2WBFX 1MEGA 3LFYA 2DJGB 1KFUL 2G6DA 3N3KA 2VHFA 4WA6A 4X6HA 3I3TA 3CBJA 1FH0A 3P5XA 3HHAA 2VHSA 1U9QX 2FO5A 3H6SA 1MIRA 1W4TA 2XU5A 3S3QA 1KFXL 1AYVA 3WXFA 3QT4A 2F7DA 4BSQA 5PADA 2IPPB 4DMYA 3PNRA 1F2BA 1YK7A 5EF4A 2XU1A 1YK8A 1POPA 1JQPA 1K3BB 1KHPA 3H7DA 3RVVA 1AECA 1AYWA 4PP2E 3MHSA 1CB5A 1GX3A 4KLBA 1ZCMA 3HHIA 4X6IA 2BDZA 2AYNA 1W5RA 1PCIA 1MEMA 3BOWA 1QOLA 2C0YA 1BGOA 3WXEA 1STFE 2DCAA 2AU1A 2DCBA 2Y6EA 1TL9A 4N79A 3H8CA 3LTWA 4XR7A 4YV8A 1O0EA 1W6FA 1Y4HA 4N8WA 4BS6A 2CIOA 4XUIA 4CDDB 4YYUA 2OULA 2HH5A 3MORA 4QBBA 4MZOA 4NV8A 2FQ9A 3N3GA 2XU4A 2YJ2A 2ARYA 1MDWA 1U9VA 1HUCB 3OVXA 2IBIA 1PPOA 2OZ2A 1CPJA 1SNKA 3H89A 2CB5A 3O1GA 3AI8A 2DC9A 1A6RA 3K8UA 1QDQA 4W5BA 2JQFR 4AXLA 4BPVA 2PREA 1BY8A 3M99A 2NQIA 3IV2A 1F2AA 2R9NA 1ME3A 3ERVA 4Q8HA 2NQAA 1U9WA 3BCNA 3V6CA 4YYQA 3PBHA 1QXPA 2VFBA 2HD5A 1CJLA 1IWDA 3HD3A 1EWMA 2VFCA 1YALA 2B1MA 4P6GA 1ITOA 4BQVA 1NLJA 4BS5A 4PI3A 3ZUAA 3CH3X 4CZWA 3E1ZB 2E01A 2AIMA 4YYRA 3F75A 1PXVA 2DJFB 2DC6A 2H7JA 1EWOA 2OP3A 5EGWA 2O6XA 1SP4B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1U5I A;  2GFO A;  3TNX A;  1THE A;  2R9C A;  5CVM A;  2AS8 A;  3QJ3 A;  3LXS A;  1NQC A;  3H8B A;  3F5V A;  1EF7 A;  2F1G A;  2YJ9 A;  2AYO A;  4YVA A;  4QH6 A;  4W5C A;  2FTD A;  1GEC E;  1MS6 A;  2FT2 A;  7PCK A;  2G8E A;  1PIP A;  4YYS A;  1CQD A;  1M6D A;  2DC8 A;  4N4Z A;  1AIM A;  1AU3 A;  2DCD A;  1PPD A;  3MTN A;  2AUX A;  4RY2 A;  2E02 A;  1GLO A;  4FJC A;  3U8E A;  5CHV A;  5FPW A;  4YYV A;  2HHN A;  4Q8G A;  2YJC A;  1TU6 A;  2PAD A;  4OEL A;  1VJV A;  4AXM A;  1F2C A;  1AU2 A;  3OF9 A;  2PNS A;  1AYU A;  4QRV A;  1S4V A;  2ATO A;  1CS8 A;  2P7U A;  3D6S A;  5F02 A;  3KWB X;  3P5U A;  3O0U A;  3BPM A;  3BC3 A;  4ZUX U;  2FRA A;  2B1N A;  2AUZ A;  1CSB B;  3RVX A;  4QRG A;  4MSX A;  1MHW A;  1CTE A;  5J94 A;  2BDL A;  2XU3 A;  2AVW A;  1PE6 A;  1KXR A;  1QMY A;  3DF0 A;  3P5V A;  2R9O A;  4FK5 A;  1ICF A;  1XKG A;  1Y08 A;  2DZZ A;  1U9X A;  1AU4 A;  1ME4 A;  3IUT A;  2JQG R;  4CDF B;  1ATK A;  1NPZ A;  5A24 A;  4I07 A;  1GMY A;  2HXZ A;  5CHT A;  5JH3 A;  3MHH A;  1EWP A;  2G8J A;  2DZY A;  3BWK A;  3CH2 X;  3GCB A;  1PAD A;  4I05 A;  3BPF A;  3K9M A;  3IHP A;  4FIP A;  1ZIV A;  4G54 A;  1DF0 A;  4MZS A;  2FYE A;  1PBH A;  4I04 A;  3HWN A;  3C9E A;  1NL6 A;  1YT7 A;  3V6E A;  3PW3 A;  2PBH A;  3QSD A;  3I06 A;  2NQD B;  2YJB A;  3OVZ A;  5K16 A;  4PP1 A;  3OF8 A;  3OIS A;  4OEM A;  3KX1 A;  4QRX A;  1X9Y A;  2GHU A;  3S3R A;  2FRQ A;  3IEJ A;  1TLO A;  3IMA A;  2NQG A;  3KFQ A;  1KHQ A;  1EWL A;  3RVW A;  5JA7 A;  2Y5B A;  1PPN A;  3NHE A;  1PPP A;  3KKU A;  3KW9 A;  2R6N A;  4K7C A;  1Q6K A;  1YVB A;  4CDC B;  3KWZ A;  4YYW A;  1BQI A;  1AU0 A;  4CDE B;  2P86 A;  2R9F A;  4DMX A;  2DCC A;  1BP4 A;  1CV8 A;  1DEU A;  1F29 A;  1NB5 A;  4W4U A;  5CVN B;  4PAD A;  3WXG A;  6PAD A;  9PAP A;  5CVO B;  4P6E A;  3P5W A;  2G7Y A;  3IOQ A;  2FUD A;  3KSE A;  2DC7 A;  1GCB A;  1NB3 A;  2P0R A;  3USV A;  2R9M A;  1VSN A;  3K24 A;  3N4C A;  4X6J A;  2ACT A;  2E00 A;  8PCH A;  3PDF A;  3B79 A;  3CBK A;  4HWY A;  2YJ8 A;  1CVZ A;  2E03 A;  2WBF X;  1MEG A;  3LFY A;  2DJG B;  1KFU L;  2G6D A;  3N3K A;  2VHF A;  4WA6 A;  4X6H A;  3I3T A;  3CBJ A;  1FH0 A;  3P5X A;  3HHA A;  2VHS A;  1U9Q X;  2FO5 A;  3H6S A;  1MIR A;  2XU5 A;  3S3Q A;  1KFX L;  1AYV A;  3WXF A;  3QT4 A;  2F7D A;  4BSQ A;  5PAD A;  2IPP B;  4DMY A;  3PNR A;  1F2B A;  1YK7 A;  5EF4 A;  2XU1 A;  1YK8 A;  1POP A;  1JQP A;  1K3B B;  1KHP A;  3H7D A;  3RVV A;  1AEC A;  1AYW A;  4PP2 E;  3MHS A;  1CB5 A;  4KLB A;  1ZCM A;  3HHI A;  4X6I A;  2BDZ A;  2AYN A;  1PCI A;  1MEM A;  3BOW A;  1QOL A;  2C0Y A;  1BGO A;  3WXE A;  1STF E;  2DCA A;  2AU1 A;  2DCB A;  2Y6E A;  1TL9 A;  4N79 A;  3H8C A;  4XR7 A;  4YV8 A;  1O0E A;  1Y4H A;  4N8W A;  4BS6 A;  2CIO A;  4XUI A;  4CDD B;  4YYU A;  2OUL A;  2HH5 A;  3MOR A;  4QBB A;  4MZO A;  2FQ9 A;  3N3G A;  2XU4 A;  2YJ2 A;  2ARY A;  1MDW A;  1U9V A;  1HUC B;  3OVX A;  2IBI A;  1PPO A;  2OZ2 A;  1CPJ A;  1SNK A;  3H89 A;  2CB5 A;  3O1G A;  3AI8 A;  2DC9 A;  1A6R A;  3K8U A;  1QDQ A;  4W5B A;  2JQF R;  4AXL A;  4BPV A;  2PRE A;  1BY8 A;  3M99 A;  2NQI A;  3IV2 A;  1F2A A;  2R9N A;  1ME3 A;  3ERV A;  4Q8H A;  2NQA A;  1U9W A;  3BCN A;  3V6C A;  4YYQ A;  3PBH A;  1QXP A;  2HD5 A;  1CJL A;  1IWD A;  3HD3 A;  1EWM A;  1YAL A;  2B1M A;  4P6G A;  1ITO A;  4BQV A;  1NLJ A;  4BS5 A;  4PI3 A;  3ZUA A;  3CH3 X;  4CZW A;  3E1Z B;  2E01 A;  2AIM A;  4YYR A;  3F75 A;  1PXV A;  2DJF B;  2DC6 A;  2H7J A;  1EWO A;  2OP3 A;  5EGW A;  2O6X A;  1SP4 B; 
#chains in the Genus database with same CATH topology
 1U5I A;  2GFO A;  3TNX A;  1THE A;  4BOP A;  2R9C A;  5CVM A;  2AS8 A;  3QJ3 A;  3LXS A;  3W30 A;  1NQC A;  3H8B A;  3F5V A;  4D8E A;  1EF7 A;  2F1G A;  2YJ9 A;  2AYO A;  4YVA A;  4QH6 A;  4WUR A;  3BY4 A;  2FTD A;  4W5C A;  1GEC E;  1MS6 A;  2FT2 A;  7PCK A;  2G8E A;  4HXD B;  1PIP A;  4YYS A;  1CQD A;  1M6D A;  2DC8 A;  4D8I A;  4N4Z A;  1AIM A;  1AU3 A;  2DCD A;  1PPD A;  5EZS A;  2J7Q C;  3MTN A;  2AUX A;  4RY2 A;  3O65 A;  2E02 A;  1GLO A;  4FJC A;  3U8E A;  3PHX A;  5CHV A;  5FPW A;  4YYV A;  2HHN A;  4Q8G A;  2YJC A;  1TU6 A;  2PAD A;  4OEL A;  1VJV A;  4AXM A;  1F2C A;  1AU2 A;  3OF9 A;  2PNS A;  4IUM A;  4PT5 A;  1AYU A;  4QRV A;  1S4V A;  3TRK A;  2ATO A;  1CS8 A;  2P7U A;  3MP2 A;  3D6S A;  1PVJ A;  5F02 A;  3KWB X;  4BOZ A;  3P5U A;  3O0U A;  3BPM A;  4GUA A;  3BC3 A;  4ZUX U;  2FRA A;  2B1N A;  2AUZ A;  3MJ5 A;  1CSB B;  3RVX A;  2JTC A;  4QRG A;  4MSX A;  1MHW A;  1CTE A;  5J94 A;  2BDL A;  4A5U A;  2XU3 A;  3BB7 A;  4OW0 A;  2AVW A;  1PE6 A;  1KXR A;  1QMY A;  3DF0 A;  2FE8 A;  3PT2 A;  3P5V A;  2R9O A;  3MTV A;  4FK5 A;  1ICF A;  1XKG A;  3TMP A;  1Y08 A;  2DZZ A;  1U9X A;  1AU4 A;  1ME4 A;  3IUT A;  2JQG R;  4CDF B;  1ATK A;  1NPZ A;  5A24 A;  4I07 A;  4M0W A;  1GMY A;  2HXZ A;  5CHT A;  5JH3 A;  3MHH A;  1EWP A;  2G8J A;  2DZY A;  3BWK A;  3CH2 X;  2HWK A;  3GCB A;  1PAD A;  1DKI A;  4I05 A;  3BPF A;  3K9M A;  2AGA A;  3IHP A;  4FIP A;  1ZIV A;  4G54 A;  1DF0 A;  4MZS A;  2FYE A;  1PBH A;  4I04 A;  4REZ A;  3HWN A;  3C9E A;  1NL6 A;  1YT7 A;  3PHW A;  3V6E A;  3PW3 A;  2PBH A;  3QSD A;  2BTW B;  3I06 A;  2NQD B;  2YJB A;  3OVZ A;  5K16 A;  4PP1 A;  3OF8 A;  3OIS A;  4OEM A;  3KX1 A;  4QRX A;  1X9Y A;  2GHU A;  3S3R A;  2FRQ A;  3IEJ A;  1TLO A;  3IMA A;  2NQG A;  3KFQ A;  1KHQ A;  4OVZ B;  1EWL A;  5E6J A;  3RVW A;  5JA7 A;  2Y5B A;  1PPN A;  3E9S A;  3NHE A;  1PPP A;  3KKU A;  3KW9 A;  4BOS A;  2R6N A;  4RF1 A;  4K7C A;  1Q6K A;  1YVB A;  4CDC B;  3KWZ A;  4YYW A;  1YZB A;  4ZTB A;  1BQI A;  1AU0 A;  4CDE B;  2P86 A;  2R9F A;  4DMX A;  2DCC A;  1BP4 A;  1CV8 A;  1DEU A;  1F29 A;  1NB5 A;  4W4U A;  5CVN B;  4PAD A;  3WXG A;  6PAD A;  9PAP A;  5CVO B;  4P6E A;  3P5W A;  2G7Y A;  3IOQ A;  3PHU A;  4BOQ A;  2FUD A;  3KSE A;  2DC7 A;  1GCB A;  1NB3 A;  2P0R A;  4MM3 B;  3B21 A;  3C0R A;  4OVZ A;  3USV A;  2R9M A;  1VSN A;  3K24 A;  3N4C A;  4X6J A;  2ACT A;  4RF0 A;  3ZNH A;  2E00 A;  8PCH A;  3PDF A;  5JZE A;  3B79 A;  3PRP A;  3CBK A;  4HWY A;  2YJ8 A;  1CVZ A;  2E03 A;  2WBF X;  1MEG A;  3LFY A;  5EZQ A;  2DJG B;  4XZX A;  1KFU L;  2G6D A;  3N3K A;  2VHF A;  4WA6 A;  4IP3 A;  4X6H A;  3I3T A;  3CBJ A;  1FH0 A;  3P5X A;  4R3D A;  3HHA A;  2VHS A;  1U9Q X;  2FO5 A;  3H6S A;  1MIR A;  3PSE A;  2XU5 A;  3S3Q A;  1KFX L;  1AYV A;  3BBA A;  3WXF A;  3QT4 A;  2F7D A;  4BSQ A;  5PAD A;  2IPP B;  2J7Q A;  4DMY A;  3PNR A;  1F2B A;  3OQC A;  1YK7 A;  5EF4 A;  2XU1 A;  1YK8 A;  1POP A;  1JQP A;  1K3B B;  1KHP A;  2BTW A;  4RNA A;  3H7D A;  3RVV A;  1AEC A;  1AYW A;  4PP2 E;  2BU3 A;  3RNV A;  3MHS A;  1CB5 A;  4KLB A;  1ZCM A;  4BOU A;  3HHI A;  4X6I A;  2BDZ A;  2AYN A;  1PCI A;  1MEM A;  3BOW A;  1QOL A;  2C0Y A;  4D8B A;  1BGO A;  4MI7 A;  3PRM A;  3WXE A;  1STF E;  2DCA A;  2AU1 A;  5KO3 A;  2DCB A;  2Y6E A;  2DOS A;  1TL9 A;  4N79 A;  3H8C A;  4XR7 A;  3W31 A;  4YV8 A;  1O0E A;  1Y4H A;  4N8W A;  4BS6 A;  2CIO A;  4XUI A;  4CDD B;  4YYU A;  2OUL A;  2HH5 A;  3MOR A;  4QBB A;  4MZO A;  4P16 A;  2FQ9 A;  3N3G A;  2XU4 A;  2YJ2 A;  2ARY A;  1MDW A;  1U9V A;  1HUC B;  3OVX A;  2IBI A;  1PPO A;  2OZ2 A;  4RKX A;  1CPJ A;  1SNK A;  3H89 A;  2CB5 A;  3O1G A;  3AI8 A;  2DC9 A;  1A6R A;  3K8U A;  1QDQ A;  4W5B A;  2JQF R;  4AXL A;  2UZJ A;  4BPV A;  2PRE A;  1BY8 A;  3M99 A;  2NQI A;  2JRI A;  3IV2 A;  1F2A A;  2R9N A;  1ME3 A;  1UKF A;  3ERV A;  4Q8H A;  2NQA A;  1U9W A;  3BCN A;  3V6C A;  4YYQ A;  3PBH A;  1QXP A;  2HD5 A;  1CJL A;  1IWD A;  3HD3 A;  1EWM A;  1YAL A;  2B1M A;  4P6G A;  1ITO A;  4BQV A;  1NLJ A;  4BS5 A;  4PI3 A;  3ZUA A;  3CH3 X;  4CZW A;  3E1Z B;  3IFU A;  2Z84 A;  2E01 A;  2AIM A;  4YYR A;  3F75 A;  1PXV A;  2DJF B;  2DC6 A;  2H7J A;  1EWO A;  2OP3 A;  5EGW A;  2O6X A;  1SP4 B; 
#chains in the Genus database with same CATH homology
 1U5I A;  2GFO A;  3TNX A;  1THE A;  2R9C A;  5CVM A;  2AS8 A;  3QJ3 A;  3LXS A;  1NQC A;  3H8B A;  3F5V A;  1EF7 A;  2F1G A;  2YJ9 A;  2AYO A;  4YVA A;  4QH6 A;  4W5C A;  2FTD A;  1GEC E;  1MS6 A;  2FT2 A;  7PCK A;  2G8E A;  1PIP A;  4YYS A;  1CQD A;  1M6D A;  2DC8 A;  4N4Z A;  1AIM A;  1AU3 A;  2DCD A;  1PPD A;  3MTN A;  2AUX A;  4RY2 A;  2E02 A;  1GLO A;  4FJC A;  3U8E A;  5CHV A;  5FPW A;  4YYV A;  2HHN A;  4Q8G A;  2YJC A;  1TU6 A;  2PAD A;  4OEL A;  1VJV A;  4AXM A;  1F2C A;  1AU2 A;  3OF9 A;  2PNS A;  1AYU A;  4QRV A;  1S4V A;  2ATO A;  1CS8 A;  2P7U A;  3D6S A;  5F02 A;  3KWB X;  3P5U A;  3O0U A;  3BPM A;  3BC3 A;  4ZUX U;  2FRA A;  2B1N A;  2AUZ A;  1CSB B;  3RVX A;  4QRG A;  4MSX A;  1MHW A;  1CTE A;  5J94 A;  2BDL A;  2XU3 A;  2AVW A;  1PE6 A;  1KXR A;  1QMY A;  3DF0 A;  3P5V A;  2R9O A;  4FK5 A;  1ICF A;  1XKG A;  1Y08 A;  2DZZ A;  1U9X A;  1AU4 A;  1ME4 A;  3IUT A;  2JQG R;  4CDF B;  1ATK A;  1NPZ A;  5A24 A;  4I07 A;  1GMY A;  2HXZ A;  5CHT A;  5JH3 A;  3MHH A;  1EWP A;  2G8J A;  2DZY A;  3BWK A;  3CH2 X;  3GCB A;  1PAD A;  4I05 A;  3BPF A;  3K9M A;  3IHP A;  4FIP A;  1ZIV A;  4G54 A;  1DF0 A;  4MZS A;  2FYE A;  1PBH A;  4I04 A;  3HWN A;  3C9E A;  1NL6 A;  1YT7 A;  3V6E A;  3PW3 A;  2PBH A;  3QSD A;  3I06 A;  2NQD B;  2YJB A;  3OVZ A;  5K16 A;  4PP1 A;  3OF8 A;  3OIS A;  4OEM A;  3KX1 A;  4QRX A;  1X9Y A;  2GHU A;  3S3R A;  2FRQ A;  3IEJ A;  1TLO A;  3IMA A;  2NQG A;  3KFQ A;  1KHQ A;  1EWL A;  3RVW A;  5JA7 A;  1E2T A;  2Y5B A;  1PPN A;  3NHE A;  1PPP A;  3KKU A;  3KW9 A;  2R6N A;  4K7C A;  2BSZ A;  1Q6K A;  1YVB A;  4CDC B;  3KWZ A;  4YYW A;  1BQI A;  1AU0 A;  4CDE B;  2P86 A;  2R9F A;  4DMX A;  2DCC A;  1BP4 A;  1CV8 A;  1DEU A;  1F29 A;  1NB5 A;  4W4U A;  5CVN B;  4PAD A;  3WXG A;  6PAD A;  9PAP A;  4GUZ A;  5CVO B;  4P6E A;  3P5W A;  2G7Y A;  3IOQ A;  3D9W A;  4NV7 A;  2FUD A;  3KSE A;  2DC7 A;  1GCB A;  1NB3 A;  2P0R A;  3USV A;  2R9M A;  1VSN A;  3K24 A;  3N4C A;  4X6J A;  2ACT A;  4C5P A;  2E00 A;  8PCH A;  3PDF A;  3B79 A;  3CBK A;  4B55 A;  4HWY A;  4BGF A;  2YJ8 A;  1CVZ A;  2E03 A;  2WBF X;  1MEG A;  3LFY A;  2DJG B;  1KFU L;  2G6D A;  3N3K A;  2VHF A;  4WA6 A;  4X6H A;  3I3T A;  3CBJ A;  1FH0 A;  3P5X A;  3HHA A;  2VHS A;  1U9Q X;  2FO5 A;  3H6S A;  1MIR A;  1W4T A;  2XU5 A;  3S3Q A;  1KFX L;  1AYV A;  3WXF A;  3QT4 A;  2F7D A;  4BSQ A;  5PAD A;  2IPP B;  4DMY A;  3PNR A;  1F2B A;  1YK7 A;  5EF4 A;  2XU1 A;  1YK8 A;  1POP A;  1JQP A;  1K3B B;  1KHP A;  3H7D A;  3RVV A;  1AEC A;  1AYW A;  4PP2 E;  3MHS A;  1CB5 A;  1GX3 A;  4KLB A;  1ZCM A;  3HHI A;  4X6I A;  2BDZ A;  2AYN A;  1W5R A;  1PCI A;  1MEM A;  3BOW A;  1QOL A;  2C0Y A;  1BGO A;  3WXE A;  1STF E;  2DCA A;  2AU1 A;  2DCB A;  2Y6E A;  1TL9 A;  4N79 A;  3H8C A;  3LTW A;  4XR7 A;  4YV8 A;  1O0E A;  1W6F A;  1Y4H A;  4N8W A;  4BS6 A;  2CIO A;  4XUI A;  4CDD B;  4YYU A;  2OUL A;  2HH5 A;  3MOR A;  4QBB A;  4MZO A;  4NV8 A;  2FQ9 A;  3N3G A;  2XU4 A;  2YJ2 A;  2ARY A;  1MDW A;  1U9V A;  1HUC B;  3OVX A;  2IBI A;  1PPO A;  2OZ2 A;  1CPJ A;  1SNK A;  3H89 A;  2CB5 A;  3O1G A;  3AI8 A;  2DC9 A;  1A6R A;  3K8U A;  1QDQ A;  4W5B A;  2JQF R;  4AXL A;  4BPV A;  2PRE A;  1BY8 A;  3M99 A;  2NQI A;  3IV2 A;  1F2A A;  2R9N A;  1ME3 A;  3ERV A;  4Q8H A;  2NQA A;  1U9W A;  3BCN A;  3V6C A;  4YYQ A;  3PBH A;  1QXP A;  2VFB A;  2HD5 A;  1CJL A;  1IWD A;  3HD3 A;  1EWM A;  2VFC A;  1YAL A;  2B1M A;  4P6G A;  1ITO A;  4BQV A;  1NLJ A;  4BS5 A;  4PI3 A;  3ZUA A;  3CH3 X;  4CZW A;  3E1Z B;  2E01 A;  2AIM A;  4YYR A;  3F75 A;  1PXV A;  2DJF B;  2DC6 A;  2H7J A;  1EWO A;  2OP3 A;  5EGW A;  2O6X A;  1SP4 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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