2G8EA

Calpain 1 proteolytic core in complex with snj-1715, a cyclic hemiacetal-type inhibitor
Total Genus 100
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
326
structure length
326
Chain Sequence
NAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICNLTPDLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Calpain-1 catalytic subunit
publication title Calpain Inhibition by alpha-Ketoamide and Cyclic Hemiacetal Inhibitors Revealed by X-ray Crystallography
pubmed doi rcsb
source organism Rattus norvegicus
total genus 100
structure length 326
sequence length 326
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2006-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2g8eA02
4BS5A 2DC9A 1ATKA 2AU1A 3MHHA 2FO5A 3PW3A 1MDWA 1O0EA 3IHPA 3K8UA 2CB5A 1AIMA 3M99A 3IEJA 1TLOA 4FIPA 5EGWA 3N4CA 5CVNB 4BPVA 4BS6A 1F2CA 1U9WA 2YJ2A 1U9QX 4XR7A 3PDFA 2R9FA 1MIRA 4QRXA 2ACTA 2JQFR 3H8BA 3P5UA 2FT2A 2HH5A 1X9YA 3P5VA 2XU5A 2FRAA 4Q8GA 1CQDA 3P5WA 3DF0A 3H6SA 3N3GA 1AU2A 2YJ8A 2XU4A 1PPOA 1STFE 2G8JA 4MZSA 3IMAA 2FYEA 1AU3A 3H89A 4QBBA 2DCCA 1K3BB 4WA6A 3F75A 9PAPA 8PCHA 2DZZA 1EWOA 4I07A 3BOWA 1SNKA 1FH0A 4G54A 1A6RA 1PE6A 1BY8A 2IBIA 3V6EA 1DEUA 3IOQA 1U5IA 1F2AA 1AU4A 1VSNA 3KWBX 3ZUAA 1U9XA 2F7DA 2R9OA 2AUXA 2FQ9A 4N79A 5CVOB 1TL9A 2PBHA 2E00A 1AYWA 1EF7A 3PNRA 4HWYA 1IWDA 1POPA 1ZIVA 5PADA 4DMYA 1ME3A 2BDZA 3N3KA 1PPNA 2PADA 1MEMA 3OISA 1AU0A 4N4ZA 6PADA 1CTEA 4YYQA 1QOLA 3C9EA 4DMXA 1PCIA 1AECA 3TNXA 2FRQA 3OVZA 2XU1A 1EWLA 1KHQA 1Q6KA 5F02A 4I04A 4BQVA 5CHVA 1NLJA 1NB5A 3KKUA 1TU6A 4QRGA 2G7YA 3CH3X 4PP1A 4OEMA 2OULA 3MORA 2AIMA 1KXRA 2DC7A 4N8WA 2R9NA 3WXFA 2XU3A 1CJLA 1NL6A 4KLBA 3LFYA 1M6DA 4AXMA 2B1NA 1DF0A 4W4UA 2ATOA 2HHNA 1JQPA 2HXZA 2DCAA 2F1GA 4P6EA 1CVZA 1PPDA 1ITOA 3HD3A 4YYUA 4BSQA 2DJGB 2FTDA 4QH6A 1EWMA 3KWZA 2CIOA 1CB5A 1NPZA 2DCBA 3BCNA 3HWNA 1YT7A 1ME4A 4CDEB 3OF8A 1GMYA 2P86A 3O1GA 2Y6EA 3S3RA 4YVAA 3OVXA 1PBHA 2NQAA 1MHWA 4K7CA 1F29A 2WBFX 1YK7A 1QXPA 2AYNA 4X6HA 2DC6A 1HUCB 3IV2A 1GCBA 4RY2A 2ARYA 1XKGA 3BWKA 3WXEA 4AXLA 4ZUXU 1THEA 4W5CA 2NQGA 5J94A 1AYVA 3I06A 5K16A 2C0YA 1YK8A 4PI3A 2E03A 3PBHA 3WXGA 5EF4A 2HD5A 2NQDB 1MEGA 2DC8A 3BPFA 2YJCA 4XUIA 3LXSA 3ERVA 3AI8A 3H8CA 4YYSA 3OF9A 3I3TA 3E1ZB 1PPPA 1SP4B 1NQCA 2FUDA 2YJBA 4YV8A 1S4VA 3CH2X 3KW9A 1KFUL 1ZCMA 3H7DA 4Q8HA 3HHIA 4P6GA 2GHUA 2PREA 3NHEA 4FJCA 2E02A 1VJVA 4FK5A 2BDLA 3QSDA 3KSEA 2R6NA 2R9CA 2P0RA 2IPPB 1QDQA 1YALA 4W5BA 1BP4A 4CZWA 2PNSA 1PXVA 2H7JA 3MHSA 4OELA 4X6JA 3IUTA 4PP2E 2P7UA 1CV8A 2GFOA 2AYOA 1Y4HA 5CVMA 4CDCB 3BPMA 1PADA 1GLOA 4MSXA 2R9MA 3CBJA 1YVBA 2DCDA 2G6DA 1EWPA 2JQGR 3BC3A 1GECE 5JA7A 4I05A 2E01A 1NB3A 3D6SA 4PADA 2NQIA 7PCKA 3U8EA 4YYRA 5FPWA 4X6IA 2AS8A 1CSBB 2G8EA 2B1MA 3CBKA 2VHFA 1MS6A 1BQIA 1KFXL 1QMYA 3S3QA 2DJFB 5CHTA 3QT4A 2VHSA 3O0UA 3B79A 3RVVA 3HHAA 4MZOA 2AUZA 5JH3A 5A24A 1KHPA 3KFQA 1U9VA 3GCBA 3MTNA 1CPJA 3K9MA 1PIPA 1Y08A 2OP3A 4CDDB 2O6XA 4YYVA 4CDFB 1F2BA 3RVXA 1CS8A 2YJ9A 3KX1A 2Y5BA 4QRVA 1BGOA 2DZYA 4YYWA 2AVWA 3USVA 1ICFA 3K24A 3P5XA 2OZ2A 3F5VA 3V6CA 3QJ3A 1AYUA 3RVWA
chains in the Genus database with same CATH superfamily
4BS5A 2DC9A 1ATKA 2AU1A 3MHHA 2FO5A 4BOZA 3PW3A 1MDWA 1O0EA 4RF0A 3IHPA 3K8UA 2CB5A 1AIMA 2FE8A 3M99A 3IEJA 1TLOA 4FIPA 5EGWA 3N4CA 5CVNB 4BPVA 4BS6A 1F2CA 1U9WA 2YJ2A 1U9QX 4XR7A 3PDFA 4MM3B 2R9FA 2Z84A 1MIRA 4QRXA 2ACTA 4A5UA 2JQFR 3H8BA 3P5UA 2FT2A 2HH5A 1X9YA 3P5VA 2XU5A 2FRAA 4Q8GA 1CQDA 3P5WA 3DF0A 1YZBA 3H6SA 3N3GA 1AU2A 2YJ8A 5KO3A 2XU4A 1PPOA 1STFE 2G8JA 3E9SA 4IUMA 3IMAA 4MZSA 2FYEA 1AU3A 3H89A 5E6JA 4QBBA 2DCCA 1K3BB 4WA6A 3F75A 9PAPA 8PCHA 2DZZA 1EWOA 4OVZB 4I07A 3BOWA 1SNKA 1FH0A 4G54A 3PRMA 1A6RA 1PE6A 1BY8A 2IBIA 3V6EA 1DEUA 3IOQA 1U5IA 1F2AA 1AU4A 1VSNA 3KWBX 4REZA 3ZUAA 1U9XA 2F7DA 2R9OA 2AUXA 2FQ9A 4N79A 5CVOB 3O65A 1TL9A 2PBHA 2E00A 1AYWA 2JRIA 1EF7A 3PNRA 4HWYA 5EZQA 1IWDA 1POPA 3PHUA 3ZNHA 1ZIVA 5PADA 4DMYA 1ME3A 2BDZA 3N3KA 4P16A 1PPNA 2PADA 1MEMA 3OISA 1AU0A 4N4ZA 6PADA 4RKXA 1CTEA 4YYQA 1QOLA 3C9EA 4DMXA 1PCIA 1AECA 3TNXA 2FRQA 4RF1A 4D8IA 3OVZA 2XU1A 1EWLA 1KHQA 1Q6KA 5F02A 4I04A 4BQVA 5CHVA 1NLJA 1NB5A 3KKUA 1TU6A 4QRGA 2G7YA 1DKIA 3CH3X 4PP1A 4OEMA 4D8BA 2OULA 3MORA 2AIMA 1KXRA 1UKFA 2DC7A 4N8WA 2R9NA 3WXFA 2XU3A 4R3DA 4OW0A 1CJLA 2J7QC 1NL6A 4KLBA 3LFYA 1M6DA 4AXMA 4PT5A 2B1NA 1DF0A 4W4UA 2ATOA 2HHNA 1JQPA 2HXZA 4D8EA 3PSEA 2DCAA 2F1GA 4P6EA 1CVZA 1PPDA 1ITOA 3HD3A 4YYUA 4BSQA 2DJGB 2FTDA 4QH6A 1EWMA 3KWZA 2CIOA 1CB5A 1NPZA 2DCBA 3BCNA 2J7QA 3HWNA 1YT7A 1ME4A 4CDEB 3OF8A 1GMYA 2P86A 3O1GA 2Y6EA 3S3RA 4YVAA 4GUAA 3OVXA 1PBHA 3MJ5A 2NQAA 1MHWA 4K7CA 4BOSA 1F29A 2WBFX 1YK7A 4OVZA 3BB7A 3BBAA 1QXPA 2AYNA 4X6HA 2DC6A 1HUCB 3IFUA 3IV2A 1GCBA 4RY2A 2ARYA 3C0RA 1XKGA 3BWKA 3WXEA 4AXLA 3BY4A 4ZUXU 1THEA 4MI7A 4W5CA 2NQGA 5J94A 1AYVA 3I06A 5K16A 2C0YA 4XZXA 1YK8A 4PI3A 2E03A 3PBHA 3WXGA 5EF4A 2HD5A 2NQDB 1MEGA 2DC8A 3BPFA 2YJCA 4XUIA 3LXSA 3ERVA 3MP2A 3AI8A 3W30A 3H8CA 4YYSA 3PHXA 4WURA 3OF9A 3TMPA 3I3TA 3E1ZB 1PPPA 4BOUA 1SP4B 1NQCA 2FUDA 2YJBA 4YV8A 1S4VA 3CH2X 3KW9A 1KFUL 1ZCMA 2BTWB 3OQCA 3H7DA 4Q8HA 5JZEA 2HWKA 3HHIA 4P6GA 2GHUA 2PREA 2BTWA 3NHEA 4FJCA 3B21A 2E02A 1VJVA 4FK5A 2BDLA 5EZSA 3QSDA 3KSEA 2R6NA 3TRKA 2R9CA 2P0RA 2IPPB 1QDQA 1YALA 4W5BA 1BP4A 4CZWA 4BOQA 2PNSA 1PXVA 2H7JA 3MHSA 4OELA 4X6JA 3IUTA 4PP2E 2P7UA 1CV8A 2GFOA 2AYOA 1Y4HA 4ZTBA 5CVMA 4CDCB 3W31A 3BPMA 2DOSA 1PADA 1GLOA 4MSXA 2R9MA 3CBJA 1YVBA 2DCDA 2G6DA 1EWPA 2JQGR 3BC3A 1GECE 5JA7A 4I05A 2E01A 1NB3A 3D6SA 4PADA 4RNAA 2NQIA 2AGAA 7PCKA 3MTVA 3U8EA 4BOPA 2BU3A 4YYRA 5FPWA 4X6IA 2AS8A 4HXDB 1CSBB 4IP3A 2G8EA 2B1MA 3CBKA 2VHFA 1MS6A 1BQIA 3RNVA 1KFXL 1QMYA 3S3QA 2DJFB 5CHTA 3PHWA 3QT4A 2VHSA 3O0UA 3B79A 3RVVA 3HHAA 3PT2A 4MZOA 2AUZA 5JH3A 2UZJA 5A24A 1KHPA 3KFQA 1U9VA 3GCBA 3MTNA 1CPJA 3K9MA 1PIPA 1Y08A 2OP3A 4CDDB 2O6XA 4YYVA 4CDFB 4M0WA 1F2BA 3RVXA 1CS8A 2YJ9A 3KX1A 2JTCA 2Y5BA 4QRVA 1BGOA 1PVJA 2DZYA 4YYWA 2AVWA 3USVA 1ICFA 3K24A 3P5XA 2OZ2A 3F5VA 3PRPA 3V6CA 3QJ3A 1AYUA 3RVWA
chains in the Genus database with same CATH topology
4BS5A 2DC9A 1ATKA 3LTWA 2AU1A 3MHHA 2FO5A 3PW3A 1MDWA 1O0EA 3IHPA 3K8UA 2CB5A 1AIMA 3M99A 3IEJA 1TLOA 4FIPA 5EGWA 3N4CA 5CVNB 4BPVA 4BS6A 1F2CA 1U9WA 2YJ2A 1U9QX 4XR7A 3PDFA 2R9FA 1MIRA 4QRXA 2ACTA 2JQFR 3H8BA 3P5UA 2FT2A 2HH5A 1X9YA 3P5VA 2XU5A 2FRAA 4Q8GA 1CQDA 3P5WA 3DF0A 3H6SA 3N3GA 1AU2A 2YJ8A 2XU4A 1PPOA 1STFE 2G8JA 4MZSA 3IMAA 2FYEA 1AU3A 3H89A 4QBBA 2DCCA 1K3BB 4WA6A 3F75A 9PAPA 8PCHA 2DZZA 1EWOA 4I07A 3BOWA 1SNKA 1FH0A 4G54A 1A6RA 1PE6A 1BY8A 2IBIA 3V6EA 1DEUA 3IOQA 1U5IA 1F2AA 1AU4A 1VSNA 3KWBX 3ZUAA 1U9XA 2F7DA 2R9OA 4C5PA 2AUXA 2FQ9A 4N79A 5CVOB 1TL9A 2PBHA 2E00A 1AYWA 1EF7A 3PNRA 4HWYA 1IWDA 1POPA 1ZIVA 5PADA 4DMYA 1ME3A 2BDZA 3N3KA 1PPNA 2PADA 1MEMA 3OISA 1AU0A 4N4ZA 6PADA 1CTEA 4YYQA 1QOLA 3C9EA 4DMXA 1PCIA 1AECA 3TNXA 2FRQA 3OVZA 2VFBA 2XU1A 1EWLA 1KHQA 1Q6KA 5F02A 4I04A 4BQVA 5CHVA 4B55A 1NLJA 1NB5A 3KKUA 1TU6A 4QRGA 2G7YA 3CH3X 4PP1A 4OEMA 2OULA 3MORA 2AIMA 1KXRA 2DC7A 4N8WA 2R9NA 3WXFA 2XU3A 1CJLA 1NL6A 4KLBA 3LFYA 1M6DA 4AXMA 2B1NA 1DF0A 4W4UA 2ATOA 2HHNA 1JQPA 2HXZA 2DCAA 2F1GA 4P6EA 1CVZA 1PPDA 1ITOA 3HD3A 4YYUA 4BSQA 2DJGB 2FTDA 4QH6A 1EWMA 4BGFA 3KWZA 2CIOA 1CB5A 1E2TA 1NPZA 2DCBA 3BCNA 4NV7A 3HWNA 1YT7A 1ME4A 4CDEB 3OF8A 1GMYA 2P86A 3O1GA 2Y6EA 3S3RA 4YVAA 3OVXA 1PBHA 2NQAA 1MHWA 4K7CA 1F29A 2WBFX 1YK7A 1QXPA 2AYNA 2VFCA 4X6HA 2DC6A 1HUCB 3IV2A 1GCBA 4RY2A 2ARYA 1XKGA 3BWKA 3WXEA 4AXLA 4ZUXU 1THEA 1GX3A 4W5CA 2NQGA 5J94A 1AYVA 3I06A 5K16A 2C0YA 1YK8A 4PI3A 2E03A 3PBHA 3WXGA 2BSZA 5EF4A 2HD5A 2NQDB 1MEGA 2DC8A 3BPFA 2YJCA 4XUIA 3LXSA 3ERVA 3AI8A 3H8CA 4YYSA 3OF9A 3I3TA 3E1ZB 1PPPA 1SP4B 1NQCA 2FUDA 2YJBA 4YV8A 1S4VA 3CH2X 3KW9A 1KFUL 1ZCMA 3H7DA 4Q8HA 3HHIA 4P6GA 2GHUA 2PREA 3NHEA 4FJCA 2E02A 1VJVA 4FK5A 2BDLA 3QSDA 3KSEA 2R6NA 2R9CA 2P0RA 2IPPB 1QDQA 1YALA 4W5BA 1BP4A 4CZWA 4NV8A 2PNSA 1PXVA 2H7JA 3MHSA 4OELA 4X6JA 3IUTA 4PP2E 2P7UA 1CV8A 2GFOA 2AYOA 1Y4HA 5CVMA 4CDCB 4GUZA 3BPMA 1PADA 1GLOA 4MSXA 2R9MA 3CBJA 1YVBA 2DCDA 2G6DA 1EWPA 2JQGR 3BC3A 1GECE 5JA7A 4I05A 2E01A 1NB3A 3D6SA 4PADA 2NQIA 7PCKA 3U8EA 4YYRA 5FPWA 4X6IA 2AS8A 1CSBB 2G8EA 2B1MA 3CBKA 2VHFA 1MS6A 1BQIA 1KFXL 1QMYA 3S3QA 2DJFB 1W5RA 5CHTA 3QT4A 2VHSA 3O0UA 3B79A 3RVVA 3HHAA 4MZOA 2AUZA 5JH3A 5A24A 1KHPA 3KFQA 1U9VA 3GCBA 3MTNA 1CPJA 1W6FA 3K9MA 1PIPA 1Y08A 2OP3A 3D9WA 4CDDB 2O6XA 4YYVA 4CDFB 1F2BA 3RVXA 1CS8A 2YJ9A 3KX1A 2Y5BA 4QRVA 1BGOA 2DZYA 4YYWA 2AVWA 3USVA 1ICFA 3K24A 3P5XA 2OZ2A 1W4TA 3F5VA 3V6CA 3QJ3A 1AYUA 3RVWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BS5 A;  2DC9 A;  1ATK A;  2AU1 A;  3MHH A;  2FO5 A;  3PW3 A;  1MDW A;  1O0E A;  3IHP A;  3K8U A;  2CB5 A;  1AIM A;  3M99 A;  3IEJ A;  1TLO A;  4FIP A;  5EGW A;  3N4C A;  5CVN B;  4BPV A;  4BS6 A;  1F2C A;  1U9W A;  2YJ2 A;  1U9Q X;  4XR7 A;  3PDF A;  2R9F A;  1MIR A;  4QRX A;  2ACT A;  2JQF R;  3H8B A;  3P5U A;  2FT2 A;  2HH5 A;  1X9Y A;  3P5V A;  2XU5 A;  2FRA A;  4Q8G A;  1CQD A;  3P5W A;  3DF0 A;  3H6S A;  3N3G A;  1AU2 A;  2YJ8 A;  2XU4 A;  1PPO A;  1STF E;  2G8J A;  4MZS A;  3IMA A;  2FYE A;  1AU3 A;  3H89 A;  4QBB A;  2DCC A;  1K3B B;  4WA6 A;  3F75 A;  9PAP A;  8PCH A;  2DZZ A;  1EWO A;  4I07 A;  3BOW A;  1SNK A;  1FH0 A;  4G54 A;  1A6R A;  1PE6 A;  1BY8 A;  2IBI A;  3V6E A;  1DEU A;  3IOQ A;  1U5I A;  1F2A A;  1AU4 A;  1VSN A;  3KWB X;  3ZUA A;  1U9X A;  2F7D A;  2R9O A;  2AUX A;  2FQ9 A;  4N79 A;  5CVO B;  1TL9 A;  2PBH A;  2E00 A;  1AYW A;  1EF7 A;  3PNR A;  4HWY A;  1IWD A;  1POP A;  1ZIV A;  5PAD A;  4DMY A;  1ME3 A;  2BDZ A;  3N3K A;  1PPN A;  2PAD A;  1MEM A;  3OIS A;  1AU0 A;  4N4Z A;  6PAD A;  1CTE A;  4YYQ A;  1QOL A;  3C9E A;  4DMX A;  1PCI A;  1AEC A;  3TNX A;  2FRQ A;  3OVZ A;  2XU1 A;  1EWL A;  1KHQ A;  1Q6K A;  5F02 A;  4I04 A;  4BQV A;  5CHV A;  1NLJ A;  1NB5 A;  3KKU A;  1TU6 A;  4QRG A;  2G7Y A;  3CH3 X;  4PP1 A;  4OEM A;  2OUL A;  3MOR A;  2AIM A;  1KXR A;  2DC7 A;  4N8W A;  2R9N A;  3WXF A;  2XU3 A;  1CJL A;  1NL6 A;  4KLB A;  3LFY A;  1M6D A;  4AXM A;  2B1N A;  1DF0 A;  4W4U A;  2ATO A;  2HHN A;  1JQP A;  2HXZ A;  2DCA A;  2F1G A;  4P6E A;  1CVZ A;  1PPD A;  1ITO A;  3HD3 A;  4YYU A;  4BSQ A;  2DJG B;  2FTD A;  4QH6 A;  1EWM A;  3KWZ A;  2CIO A;  1CB5 A;  1NPZ A;  2DCB A;  3BCN A;  3HWN A;  1YT7 A;  1ME4 A;  4CDE B;  3OF8 A;  1GMY A;  2P86 A;  3O1G A;  2Y6E A;  3S3R A;  4YVA A;  3OVX A;  1PBH A;  2NQA A;  1MHW A;  4K7C A;  1F29 A;  2WBF X;  1YK7 A;  1QXP A;  2AYN A;  4X6H A;  2DC6 A;  1HUC B;  3IV2 A;  1GCB A;  4RY2 A;  2ARY A;  1XKG A;  3BWK A;  3WXE A;  4AXL A;  4ZUX U;  1THE A;  4W5C A;  2NQG A;  5J94 A;  1AYV A;  3I06 A;  5K16 A;  2C0Y A;  1YK8 A;  4PI3 A;  2E03 A;  3PBH A;  3WXG A;  5EF4 A;  2HD5 A;  2NQD B;  1MEG A;  2DC8 A;  3BPF A;  2YJC A;  4XUI A;  3LXS A;  3ERV A;  3AI8 A;  3H8C A;  4YYS A;  3OF9 A;  3I3T A;  3E1Z B;  1PPP A;  1SP4 B;  1NQC A;  2FUD A;  2YJB A;  4YV8 A;  1S4V A;  3CH2 X;  3KW9 A;  1KFU L;  1ZCM A;  3H7D A;  4Q8H A;  3HHI A;  4P6G A;  2GHU A;  2PRE A;  3NHE A;  4FJC A;  2E02 A;  1VJV A;  4FK5 A;  2BDL A;  3QSD A;  3KSE A;  2R6N A;  2R9C A;  2P0R A;  2IPP B;  1QDQ A;  1YAL A;  4W5B A;  1BP4 A;  4CZW A;  2PNS A;  1PXV A;  2H7J A;  3MHS A;  4OEL A;  4X6J A;  3IUT A;  4PP2 E;  2P7U A;  1CV8 A;  2GFO A;  2AYO A;  1Y4H A;  5CVM A;  4CDC B;  3BPM A;  1PAD A;  1GLO A;  4MSX A;  2R9M A;  3CBJ A;  1YVB A;  2DCD A;  2G6D A;  1EWP A;  2JQG R;  3BC3 A;  1GEC E;  5JA7 A;  4I05 A;  2E01 A;  1NB3 A;  3D6S A;  4PAD A;  2NQI A;  7PCK A;  3U8E A;  4YYR A;  5FPW A;  4X6I A;  2AS8 A;  1CSB B;  2G8E A;  2B1M A;  3CBK A;  2VHF A;  1MS6 A;  1BQI A;  1KFX L;  1QMY A;  3S3Q A;  2DJF B;  5CHT A;  3QT4 A;  2VHS A;  3O0U A;  3B79 A;  3RVV A;  3HHA A;  4MZO A;  2AUZ A;  5JH3 A;  5A24 A;  1KHP A;  3KFQ A;  1U9V A;  3GCB A;  3MTN A;  1CPJ A;  3K9M A;  1PIP A;  1Y08 A;  2OP3 A;  4CDD B;  2O6X A;  4YYV A;  4CDF B;  1F2B A;  3RVX A;  1CS8 A;  2YJ9 A;  3KX1 A;  2Y5B A;  4QRV A;  1BGO A;  2DZY A;  4YYW A;  2AVW A;  3USV A;  1ICF A;  3K24 A;  3P5X A;  2OZ2 A;  3F5V A;  3V6C A;  3QJ3 A;  1AYU A;  3RVW A; 
#chains in the Genus database with same CATH topology
 4BS5 A;  2DC9 A;  1ATK A;  2AU1 A;  3MHH A;  2FO5 A;  4BOZ A;  3PW3 A;  1MDW A;  1O0E A;  4RF0 A;  3IHP A;  3K8U A;  2CB5 A;  1AIM A;  2FE8 A;  3M99 A;  3IEJ A;  1TLO A;  4FIP A;  5EGW A;  3N4C A;  5CVN B;  4BPV A;  4BS6 A;  1F2C A;  1U9W A;  2YJ2 A;  1U9Q X;  4XR7 A;  3PDF A;  4MM3 B;  2R9F A;  2Z84 A;  1MIR A;  4QRX A;  2ACT A;  4A5U A;  2JQF R;  3H8B A;  3P5U A;  2FT2 A;  2HH5 A;  1X9Y A;  3P5V A;  2XU5 A;  2FRA A;  4Q8G A;  1CQD A;  3P5W A;  3DF0 A;  1YZB A;  3H6S A;  3N3G A;  1AU2 A;  2YJ8 A;  5KO3 A;  2XU4 A;  1PPO A;  1STF E;  2G8J A;  3E9S A;  4IUM A;  3IMA A;  4MZS A;  2FYE A;  1AU3 A;  3H89 A;  5E6J A;  4QBB A;  2DCC A;  1K3B B;  4WA6 A;  3F75 A;  9PAP A;  8PCH A;  2DZZ A;  1EWO A;  4OVZ B;  4I07 A;  3BOW A;  1SNK A;  1FH0 A;  4G54 A;  3PRM A;  1A6R A;  1PE6 A;  1BY8 A;  2IBI A;  3V6E A;  1DEU A;  3IOQ A;  1U5I A;  1F2A A;  1AU4 A;  1VSN A;  3KWB X;  4REZ A;  3ZUA A;  1U9X A;  2F7D A;  2R9O A;  2AUX A;  2FQ9 A;  4N79 A;  5CVO B;  3O65 A;  1TL9 A;  2PBH A;  2E00 A;  1AYW A;  2JRI A;  1EF7 A;  3PNR A;  4HWY A;  5EZQ A;  1IWD A;  1POP A;  3PHU A;  3ZNH A;  1ZIV A;  5PAD A;  4DMY A;  1ME3 A;  2BDZ A;  3N3K A;  4P16 A;  1PPN A;  2PAD A;  1MEM A;  3OIS A;  1AU0 A;  4N4Z A;  6PAD A;  4RKX A;  1CTE A;  4YYQ A;  1QOL A;  3C9E A;  4DMX A;  1PCI A;  1AEC A;  3TNX A;  2FRQ A;  4RF1 A;  4D8I A;  3OVZ A;  2XU1 A;  1EWL A;  1KHQ A;  1Q6K A;  5F02 A;  4I04 A;  4BQV A;  5CHV A;  1NLJ A;  1NB5 A;  3KKU A;  1TU6 A;  4QRG A;  2G7Y A;  1DKI A;  3CH3 X;  4PP1 A;  4OEM A;  4D8B A;  2OUL A;  3MOR A;  2AIM A;  1KXR A;  1UKF A;  2DC7 A;  4N8W A;  2R9N A;  3WXF A;  2XU3 A;  4R3D A;  4OW0 A;  1CJL A;  2J7Q C;  1NL6 A;  4KLB A;  3LFY A;  1M6D A;  4AXM A;  4PT5 A;  2B1N A;  1DF0 A;  4W4U A;  2ATO A;  2HHN A;  1JQP A;  2HXZ A;  4D8E A;  3PSE A;  2DCA A;  2F1G A;  4P6E A;  1CVZ A;  1PPD A;  1ITO A;  3HD3 A;  4YYU A;  4BSQ A;  2DJG B;  2FTD A;  4QH6 A;  1EWM A;  3KWZ A;  2CIO A;  1CB5 A;  1NPZ A;  2DCB A;  3BCN A;  2J7Q A;  3HWN A;  1YT7 A;  1ME4 A;  4CDE B;  3OF8 A;  1GMY A;  2P86 A;  3O1G A;  2Y6E A;  3S3R A;  4YVA A;  4GUA A;  3OVX A;  1PBH A;  3MJ5 A;  2NQA A;  1MHW A;  4K7C A;  4BOS A;  1F29 A;  2WBF X;  1YK7 A;  4OVZ A;  3BB7 A;  3BBA A;  1QXP A;  2AYN A;  4X6H A;  2DC6 A;  1HUC B;  3IFU A;  3IV2 A;  1GCB A;  4RY2 A;  2ARY A;  3C0R A;  1XKG A;  3BWK A;  3WXE A;  4AXL A;  3BY4 A;  4ZUX U;  1THE A;  4MI7 A;  4W5C A;  2NQG A;  5J94 A;  1AYV A;  3I06 A;  5K16 A;  2C0Y A;  4XZX A;  1YK8 A;  4PI3 A;  2E03 A;  3PBH A;  3WXG A;  5EF4 A;  2HD5 A;  2NQD B;  1MEG A;  2DC8 A;  3BPF A;  2YJC A;  4XUI A;  3LXS A;  3ERV A;  3MP2 A;  3AI8 A;  3W30 A;  3H8C A;  4YYS A;  3PHX A;  4WUR A;  3OF9 A;  3TMP A;  3I3T A;  3E1Z B;  1PPP A;  4BOU A;  1SP4 B;  1NQC A;  2FUD A;  2YJB A;  4YV8 A;  1S4V A;  3CH2 X;  3KW9 A;  1KFU L;  1ZCM A;  2BTW B;  3OQC A;  3H7D A;  4Q8H A;  5JZE A;  2HWK A;  3HHI A;  4P6G A;  2GHU A;  2PRE A;  2BTW A;  3NHE A;  4FJC A;  3B21 A;  2E02 A;  1VJV A;  4FK5 A;  2BDL A;  5EZS A;  3QSD A;  3KSE A;  2R6N A;  3TRK A;  2R9C A;  2P0R A;  2IPP B;  1QDQ A;  1YAL A;  4W5B A;  1BP4 A;  4CZW A;  4BOQ A;  2PNS A;  1PXV A;  2H7J A;  3MHS A;  4OEL A;  4X6J A;  3IUT A;  4PP2 E;  2P7U A;  1CV8 A;  2GFO A;  2AYO A;  1Y4H A;  4ZTB A;  5CVM A;  4CDC B;  3W31 A;  3BPM A;  2DOS A;  1PAD A;  1GLO A;  4MSX A;  2R9M A;  3CBJ A;  1YVB A;  2DCD A;  2G6D A;  1EWP A;  2JQG R;  3BC3 A;  1GEC E;  5JA7 A;  4I05 A;  2E01 A;  1NB3 A;  3D6S A;  4PAD A;  4RNA A;  2NQI A;  2AGA A;  7PCK A;  3MTV A;  3U8E A;  4BOP A;  2BU3 A;  4YYR A;  5FPW A;  4X6I A;  2AS8 A;  4HXD B;  1CSB B;  4IP3 A;  2G8E A;  2B1M A;  3CBK A;  2VHF A;  1MS6 A;  1BQI A;  3RNV A;  1KFX L;  1QMY A;  3S3Q A;  2DJF B;  5CHT A;  3PHW A;  3QT4 A;  2VHS A;  3O0U A;  3B79 A;  3RVV A;  3HHA A;  3PT2 A;  4MZO A;  2AUZ A;  5JH3 A;  2UZJ A;  5A24 A;  1KHP A;  3KFQ A;  1U9V A;  3GCB A;  3MTN A;  1CPJ A;  3K9M A;  1PIP A;  1Y08 A;  2OP3 A;  4CDD B;  2O6X A;  4YYV A;  4CDF B;  4M0W A;  1F2B A;  3RVX A;  1CS8 A;  2YJ9 A;  3KX1 A;  2JTC A;  2Y5B A;  4QRV A;  1BGO A;  1PVJ A;  2DZY A;  4YYW A;  2AVW A;  3USV A;  1ICF A;  3K24 A;  3P5X A;  2OZ2 A;  3F5V A;  3PRP A;  3V6C A;  3QJ3 A;  1AYU A;  3RVW A; 
#chains in the Genus database with same CATH homology
 4BS5 A;  2DC9 A;  1ATK A;  3LTW A;  2AU1 A;  3MHH A;  2FO5 A;  3PW3 A;  1MDW A;  1O0E A;  3IHP A;  3K8U A;  2CB5 A;  1AIM A;  3M99 A;  3IEJ A;  1TLO A;  4FIP A;  5EGW A;  3N4C A;  5CVN B;  4BPV A;  4BS6 A;  1F2C A;  1U9W A;  2YJ2 A;  1U9Q X;  4XR7 A;  3PDF A;  2R9F A;  1MIR A;  4QRX A;  2ACT A;  2JQF R;  3H8B A;  3P5U A;  2FT2 A;  2HH5 A;  1X9Y A;  3P5V A;  2XU5 A;  2FRA A;  4Q8G A;  1CQD A;  3P5W A;  3DF0 A;  3H6S A;  3N3G A;  1AU2 A;  2YJ8 A;  2XU4 A;  1PPO A;  1STF E;  2G8J A;  4MZS A;  3IMA A;  2FYE A;  1AU3 A;  3H89 A;  4QBB A;  2DCC A;  1K3B B;  4WA6 A;  3F75 A;  9PAP A;  8PCH A;  2DZZ A;  1EWO A;  4I07 A;  3BOW A;  1SNK A;  1FH0 A;  4G54 A;  1A6R A;  1PE6 A;  1BY8 A;  2IBI A;  3V6E A;  1DEU A;  3IOQ A;  1U5I A;  1F2A A;  1AU4 A;  1VSN A;  3KWB X;  3ZUA A;  1U9X A;  2F7D A;  2R9O A;  4C5P A;  2AUX A;  2FQ9 A;  4N79 A;  5CVO B;  1TL9 A;  2PBH A;  2E00 A;  1AYW A;  1EF7 A;  3PNR A;  4HWY A;  1IWD A;  1POP A;  1ZIV A;  5PAD A;  4DMY A;  1ME3 A;  2BDZ A;  3N3K A;  1PPN A;  2PAD A;  1MEM A;  3OIS A;  1AU0 A;  4N4Z A;  6PAD A;  1CTE A;  4YYQ A;  1QOL A;  3C9E A;  4DMX A;  1PCI A;  1AEC A;  3TNX A;  2FRQ A;  3OVZ A;  2VFB A;  2XU1 A;  1EWL A;  1KHQ A;  1Q6K A;  5F02 A;  4I04 A;  4BQV A;  5CHV A;  4B55 A;  1NLJ A;  1NB5 A;  3KKU A;  1TU6 A;  4QRG A;  2G7Y A;  3CH3 X;  4PP1 A;  4OEM A;  2OUL A;  3MOR A;  2AIM A;  1KXR A;  2DC7 A;  4N8W A;  2R9N A;  3WXF A;  2XU3 A;  1CJL A;  1NL6 A;  4KLB A;  3LFY A;  1M6D A;  4AXM A;  2B1N A;  1DF0 A;  4W4U A;  2ATO A;  2HHN A;  1JQP A;  2HXZ A;  2DCA A;  2F1G A;  4P6E A;  1CVZ A;  1PPD A;  1ITO A;  3HD3 A;  4YYU A;  4BSQ A;  2DJG B;  2FTD A;  4QH6 A;  1EWM A;  4BGF A;  3KWZ A;  2CIO A;  1CB5 A;  1E2T A;  1NPZ A;  2DCB A;  3BCN A;  4NV7 A;  3HWN A;  1YT7 A;  1ME4 A;  4CDE B;  3OF8 A;  1GMY A;  2P86 A;  3O1G A;  2Y6E A;  3S3R A;  4YVA A;  3OVX A;  1PBH A;  2NQA A;  1MHW A;  4K7C A;  1F29 A;  2WBF X;  1YK7 A;  1QXP A;  2AYN A;  2VFC A;  4X6H A;  2DC6 A;  1HUC B;  3IV2 A;  1GCB A;  4RY2 A;  2ARY A;  1XKG A;  3BWK A;  3WXE A;  4AXL A;  4ZUX U;  1THE A;  1GX3 A;  4W5C A;  2NQG A;  5J94 A;  1AYV A;  3I06 A;  5K16 A;  2C0Y A;  1YK8 A;  4PI3 A;  2E03 A;  3PBH A;  3WXG A;  2BSZ A;  5EF4 A;  2HD5 A;  2NQD B;  1MEG A;  2DC8 A;  3BPF A;  2YJC A;  4XUI A;  3LXS A;  3ERV A;  3AI8 A;  3H8C A;  4YYS A;  3OF9 A;  3I3T A;  3E1Z B;  1PPP A;  1SP4 B;  1NQC A;  2FUD A;  2YJB A;  4YV8 A;  1S4V A;  3CH2 X;  3KW9 A;  1KFU L;  1ZCM A;  3H7D A;  4Q8H A;  3HHI A;  4P6G A;  2GHU A;  2PRE A;  3NHE A;  4FJC A;  2E02 A;  1VJV A;  4FK5 A;  2BDL A;  3QSD A;  3KSE A;  2R6N A;  2R9C A;  2P0R A;  2IPP B;  1QDQ A;  1YAL A;  4W5B A;  1BP4 A;  4CZW A;  4NV8 A;  2PNS A;  1PXV A;  2H7J A;  3MHS A;  4OEL A;  4X6J A;  3IUT A;  4PP2 E;  2P7U A;  1CV8 A;  2GFO A;  2AYO A;  1Y4H A;  5CVM A;  4CDC B;  4GUZ A;  3BPM A;  1PAD A;  1GLO A;  4MSX A;  2R9M A;  3CBJ A;  1YVB A;  2DCD A;  2G6D A;  1EWP A;  2JQG R;  3BC3 A;  1GEC E;  5JA7 A;  4I05 A;  2E01 A;  1NB3 A;  3D6S A;  4PAD A;  2NQI A;  7PCK A;  3U8E A;  4YYR A;  5FPW A;  4X6I A;  2AS8 A;  1CSB B;  2G8E A;  2B1M A;  3CBK A;  2VHF A;  1MS6 A;  1BQI A;  1KFX L;  1QMY A;  3S3Q A;  2DJF B;  1W5R A;  5CHT A;  3QT4 A;  2VHS A;  3O0U A;  3B79 A;  3RVV A;  3HHA A;  4MZO A;  2AUZ A;  5JH3 A;  5A24 A;  1KHP A;  3KFQ A;  1U9V A;  3GCB A;  3MTN A;  1CPJ A;  1W6F A;  3K9M A;  1PIP A;  1Y08 A;  2OP3 A;  3D9W A;  4CDD B;  2O6X A;  4YYV A;  4CDF B;  1F2B A;  3RVX A;  1CS8 A;  2YJ9 A;  3KX1 A;  2Y5B A;  4QRV A;  1BGO A;  2DZY A;  4YYW A;  2AVW A;  3USV A;  1ICF A;  3K24 A;  3P5X A;  2OZ2 A;  1W4T A;  3F5V A;  3V6C A;  3QJ3 A;  1AYU A;  3RVW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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