2G8EA

Calpain 1 proteolytic core in complex with snj-1715, a cyclic hemiacetal-type inhibitor
Total Genus 100
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
326
structure length
326
Chain Sequence
b'NAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICNLTPDLE'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Calpain-1 catalytic subunit
publication title Calpain Inhibition by alpha-Ketoamide and Cyclic Hemiacetal Inhibitors Revealed by X-ray Crystallography
pubmed doi rcsb
source organism Rattus norvegicus
molecule tags Hydrolase/hydrolase inhibitor
total genus 100
structure length 326
sequence length 326
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2006-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2g8eA02
3LFYA 2HH5A 3KSEA 1PIPA 2NQAA 1CTEA 1CJLA 1PE6A 2G6DA 4YYRA 3PDFA 3IHPA 3K24A 1PXVA 4W5CA 1TLOA 1KFUL 1GECE 1EF7A 2IPPB 4XR7A 3WXFA 3PBHA 4XUIA 1AU2A 3QT4A 2AUXA 1U9WA 2YJ2A 3KKUA 4YYSA 2DZYA 2DCBA 2HXZA 3N4CA 2FO5A 4YYUA 2PADA 3QJ3A 1Q6KA 3P5XA 3HD3A 5CHTA 2F7DA 4YYVA 2DC7A 3QSDA 2DC9A 4AXLA 3BCNA 2JQFR 3BPFA 3MORA 5CVOB 5K16A 3S3QA 2FTDA 1MEMA 2NQDB 1KHPA 3KWZA 3IMAA 2CB5A 5CVMA 3S3RA 5EGWA 3HWNA 2BDLA 1A6RA 3RVWA 4Q8HA 3IUTA 1EWLA 2E00A 1F29A 1POPA 3RVXA 2NQGA 5A24A 4CDCB 3LXSA 3N3KA 2FRQA 1X9YA 2XU4A 3ERVA 4RY2A 4W5BA 2R9OA 4I05A 2FT2A 3OF8A 2FRAA 2DCCA 2G7YA 4AXMA 2Y6EA 3CH3X 1CV8A 4YV8A 2AYNA 1KXRA 2DJFB 1YALA 3OF9A 2E03A 1VJVA 4YVAA 1QXPA 1Y08A 3IOQA 3K9MA 3I06A 2YJ8A 4BS5A 1STFE 1JQPA 3WXEA 3OVZA 4N8WA 2P7UA 4X6JA 2C0YA 4CDDB 1AIMA 1CPJA 4KLBA 1BP4A 1AU4A 2G8JA 3OVXA 4OELA 1QMYA 3O0UA 1F2CA 2CIOA 1GCBA 3N3GA 1ZCMA 4BS6A 1NL6A 5JA7A 4X6IA 1BGOA 3DF0A 2YJCA 1U9VA 3HHAA 2ATOA 4MSXA 4Q8GA 3AI8A 4QRXA 4X6HA 4QBBA 2DC8A 1NLJA 2VHSA 3U8EA 5J94A 1CS8A 1KFXL 2OZ2A 2BDZA 1CB5A 2XU3A 4MZOA 1AECA 3V6CA 1PBHA 1AYUA 1MEGA 2AVWA 1ZIVA 1YT7A 1KHQA 1PPPA 2P0RA 2PBHA 1AYWA 2AS8A 2AU1A 9PAPA 3BWKA 4QRVA 3B79A 3PW3A 2AYOA 2IBIA 1U9XA 3MHHA 1U9QX 4FJCA 3V6EA 1HUCB 4N79A 1MIRA 1NQCA 3CBJA 2PREA 3D6SA 2HHNA 4PI3A 3WXGA 4PP2E 3H8BA 3USVA 1K3BB 1THEA 2R9MA 1TU6A 3F5VA 3PNRA 3C9EA 1TL9A 3CH2X 4DMXA 1S4VA 1YK8A 1PADA 1CQDA 3CBKA 3IEJA 1NB5A 5EF4A 4YYWA 2JQGR 2GFOA 1PPDA 2GHUA 3HHIA 4P6EA 6PADA 1F2BA 1QOLA 2WBFX 3I3TA 4CDFB 1AU0A 3M99A 8PCHA 4P6GA 1MDWA 1AYVA 1CSBB 2P86A 2FYEA 1ME3A 4N4ZA 1MS6A 2R9CA 3KFQA 2DC6A 1O0EA 3H8CA 2AUZA 4DMYA 5PADA 1XKGA 3P5UA 3BC3A 2AIMA 2DJGB 3ZUAA 3BOWA 1F2AA 3NHEA 2XU5A 2O6XA 2G8EA 3OISA 4I04A 1EWMA 1YVBA 2VHFA 2DCAA 3BPMA 1PPNA 3RVVA 1NB3A 4FIPA 2F1GA 1PPOA 1MHWA 4CZWA 5CVNB 2DZZA 1M6DA 3H6SA 4BQVA 2Y5BA 1ITOA 1DEUA 1GMYA 3IV2A 5F02A 7PCKA 1CVZA 4HWYA 3KX1A 2B1NA 4CDEB 4WA6A 1VSNA 3H89A 2R9NA 1EWPA 3P5VA 1YK7A 4OEMA 3TNXA 3E1ZB 2OULA 2OP3A 2YJ9A 2R6NA 2PNSA 1NPZA 2E01A 2B1MA 3MTNA 2ARYA 5JH3A 3MHSA 2E02A 1IWDA 2XU1A 2NQIA 2DCDA 3GCBA 3KW9A 4I07A 1ICFA 1DF0A 1SNKA 1BQIA 4K7CA 4W4UA 1GLOA 2H7JA 1Y4HA 1U5IA 3H7DA 1PCIA 3P5WA 4ZUXU 1SP4B 2FUDA 1BY8A 1FH0A 4YYQA 2R9FA 1AU3A 4BSQA 4FK5A 4PADA 1ME4A 2HD5A 1EWOA 2ACTA 5FPWA 4G54A 4MZSA 4QRGA 4PP1A 2FQ9A 5CHVA 4BPVA 3K8UA 2YJBA 3F75A 4QH6A 3KWBX 3O1GA 1ATKA 1QDQA
chains in the Genus database with same CATH superfamily
3B21A 3LFYA 2HH5A 3KSEA 1PIPA 2NQAA 1CTEA 1CJLA 1PE6A 2G6DA 4BOQA 4YYRA 3PDFA 4MM3B 3IHPA 3K24A 1PXVA 4W5CA 1TLOA 1KFUL 1GECE 1EF7A 2IPPB 2J7QC 4XR7A 3WXFA 3PBHA 4XUIA 1AU2A 3ZNHA 3QT4A 2AUXA 3PHUA 1U9WA 2YJ2A 3KKUA 4YYSA 2DZYA 2DCBA 2HXZA 3N4CA 2FO5A 4YYUA 2HWKA 2PADA 3QJ3A 1Q6KA 2JTCA 3P5XA 3HD3A 5CHTA 2F7DA 4YYVA 2DC7A 3QSDA 3TMPA 2DC9A 4AXLA 3BCNA 2JQFR 3BPFA 3MORA 5CVOB 5K16A 3S3QA 3BB7A 2FTDA 5EZQA 1MEMA 2NQDB 1KHPA 3KWZA 4RF1A 3IMAA 2CB5A 5CVMA 3S3RA 5EGWA 4XZXA 3HWNA 2BDLA 1A6RA 4PT5A 4BOZA 3RVWA 2JRIA 4Q8HA 3IUTA 1EWLA 2E00A 1F29A 1POPA 3RVXA 2NQGA 5A24A 4CDCB 3LXSA 3N3KA 2FRQA 1X9YA 2XU4A 3ERVA 1DKIA 4RY2A 4W5BA 2R9OA 4I05A 2FT2A 3OF8A 2FRAA 2DCCA 2G7YA 4AXMA 2Y6EA 3CH3X 2BTWB 1CV8A 4YV8A 3W31A 2AYNA 1KXRA 2DJFB 1YALA 3OF9A 2E03A 3PT2A 1VJVA 4YVAA 3C0RA 1QXPA 1Y08A 3IOQA 3K9MA 3I06A 4OVZB 2YJ8A 4BS5A 1STFE 1JQPA 3WXEA 3OVZA 4N8WA 2P7UA 4X6JA 2C0YA 4CDDB 1AIMA 1CPJA 4D8BA 4KLBA 1BP4A 1AU4A 2G8JA 2AGAA 3OVXA 4R3DA 3E9SA 4OELA 1QMYA 3O0UA 1F2CA 2CIOA 1GCBA 3N3GA 1ZCMA 4BS6A 1NL6A 5JA7A 4X6IA 1BGOA 2BU3A 3DF0A 2YJCA 2FE8A 1U9VA 3HHAA 4RNAA 2ATOA 4MSXA 4Q8GA 3AI8A 4QRXA 4X6HA 4QBBA 2DC8A 1NLJA 2VHSA 4WURA 3U8EA 5J94A 3BY4A 1CS8A 1KFXL 4GUAA 4D8EA 2BTWA 2OZ2A 4ZTBA 2BDZA 1CB5A 2XU3A 4MZOA 1AECA 3V6CA 1PBHA 1AYUA 1MEGA 2AVWA 2J7QA 1ZIVA 4RKXA 4A5UA 3MJ5A 1YT7A 1KHQA 1PPPA 2P0RA 3BBAA 4IUMA 4OVZA 3PHWA 2PBHA 1AYWA 2AS8A 2AU1A 9PAPA 3BWKA 4BOSA 4OW0A 4QRVA 3B79A 3PW3A 2AYOA 3W30A 2IBIA 1U9XA 3MHHA 1PVJA 1U9QX 4FJCA 3V6EA 1HUCB 4N79A 1MIRA 1NQCA 4MI7A 3CBJA 3PRPA 4M0WA 2PREA 3D6SA 2HHNA 4PI3A 3WXGA 4REZA 4PP2E 3H8BA 3USVA 1K3BB 1THEA 2R9MA 1TU6A 3F5VA 3PNRA 3C9EA 1YZBA 1TL9A 3CH2X 4DMXA 1S4VA 1YK8A 3RNVA 3PHXA 1PADA 1CQDA 3CBKA 3IEJA 1NB5A 5EF4A 4YYWA 2JQGR 2GFOA 2UZJA 3OQCA 1PPDA 2GHUA 3HHIA 4P6EA 6PADA 1F2BA 1QOLA 2WBFX 4BOUA 3I3TA 4CDFB 1AU0A 3M99A 8PCHA 4P6GA 1MDWA 1AYVA 2DOSA 1CSBB 2P86A 2FYEA 1ME3A 4N4ZA 4P16A 1MS6A 2R9CA 5EZSA 3KFQA 2DC6A 1O0EA 3H8CA 2AUZA 4DMYA 5PADA 1XKGA 3P5UA 3BC3A 2AIMA 3IFUA 2DJGB 3ZUAA 3BOWA 3TRKA 1F2AA 3NHEA 2XU5A 2O6XA 2G8EA 3OISA 1EWMA 1YVBA 4I04A 2VHFA 2DCAA 3BPMA 1PPNA 3RVVA 1NB3A 5JZEA 4FIPA 2F1GA 1PPOA 1MHWA 4CZWA 5CVNB 5E6JA 2DZZA 1M6DA 3H6SA 4BQVA 2Y5BA 1ITOA 1DEUA 1GMYA 3IV2A 5F02A 7PCKA 1CVZA 4HWYA 3KX1A 2B1NA 4CDEB 4WA6A 1VSNA 3H89A 2R9NA 1EWPA 3P5VA 1YK7A 4OEMA 3TNXA 3E1ZB 5KO3A 2OULA 2OP3A 2YJ9A 2R6NA 2PNSA 1NPZA 2E01A 2B1MA 3MTNA 4D8IA 4BOPA 3PSEA 2ARYA 5JH3A 3MHSA 4IP3A 2E02A 1IWDA 2XU1A 3PRMA 2NQIA 2DCDA 3GCBA 3KW9A 4I07A 1ICFA 1DF0A 1SNKA 1BQIA 4K7CA 4W4UA 1GLOA 4RF0A 2H7JA 1Y4HA 1U5IA 3H7DA 1PCIA 3O65A 3P5WA 4ZUXU 1SP4B 2FUDA 1BY8A 1FH0A 4YYQA 2R9FA 1AU3A 4BSQA 4FK5A 4PADA 1ME4A 2HD5A 1UKFA 1EWOA 2ACTA 5FPWA 4G54A 4HXDB 4MZSA 4QRGA 4PP1A 2FQ9A 5CHVA 2Z84A 4BPVA 3MP2A 3K8UA 2YJBA 3F75A 3MTVA 4QH6A 3KWBX 3O1GA 1ATKA 1QDQA
chains in the Genus database with same CATH topology
3LFYA 2HH5A 3KSEA 1PIPA 2NQAA 1CTEA 1CJLA 1PE6A 2G6DA 4YYRA 3PDFA 3IHPA 3K24A 1PXVA 4W5CA 1TLOA 1KFUL 1GECE 1EF7A 2IPPB 4XR7A 3WXFA 3PBHA 4XUIA 1AU2A 3QT4A 2AUXA 1U9WA 4GUZA 2YJ2A 3KKUA 4YYSA 2DZYA 2DCBA 2HXZA 3N4CA 2FO5A 4YYUA 2PADA 3QJ3A 1Q6KA 3P5XA 3HD3A 5CHTA 2F7DA 4YYVA 2DC7A 3QSDA 2DC9A 4AXLA 3BCNA 2JQFR 3BPFA 3MORA 5CVOB 5K16A 3S3QA 2FTDA 1MEMA 2NQDB 1KHPA 3KWZA 3IMAA 2CB5A 5CVMA 3S3RA 5EGWA 3HWNA 2BDLA 1A6RA 3RVWA 4Q8HA 4BGFA 3IUTA 1EWLA 2E00A 1F29A 1POPA 3RVXA 2NQGA 5A24A 4CDCB 3LXSA 3N3KA 2FRQA 1X9YA 2XU4A 3ERVA 4RY2A 4W5BA 2R9OA 4I05A 2FT2A 3OF8A 2FRAA 2DCCA 2G7YA 4AXMA 2Y6EA 3CH3X 1CV8A 4YV8A 2AYNA 1KXRA 2DJFB 1YALA 3OF9A 2E03A 1VJVA 4YVAA 1QXPA 1Y08A 3IOQA 3K9MA 3I06A 2YJ8A 4BS5A 1STFE 1JQPA 3WXEA 3OVZA 4C5PA 4N8WA 2P7UA 4X6JA 2C0YA 4CDDB 1AIMA 1CPJA 4KLBA 1BP4A 1AU4A 2G8JA 3OVXA 4OELA 1QMYA 3O0UA 1F2CA 2CIOA 1GCBA 3N3GA 1ZCMA 4BS6A 1NL6A 5JA7A 4X6IA 1BGOA 1W5RA 3DF0A 2YJCA 1U9VA 3HHAA 2ATOA 4MSXA 2BSZA 3LTWA 4Q8GA 3AI8A 4QRXA 4X6HA 4QBBA 2DC8A 1NLJA 2VHSA 3U8EA 5J94A 1W4TA 1CS8A 1KFXL 2OZ2A 2BDZA 1CB5A 2XU3A 4MZOA 1AECA 3V6CA 1PBHA 1AYUA 1MEGA 2AVWA 1ZIVA 1YT7A 1KHQA 1PPPA 2P0RA 2PBHA 1AYWA 2AS8A 2AU1A 9PAPA 3BWKA 4QRVA 3B79A 3PW3A 2AYOA 2IBIA 3D9WA 1U9XA 4B55A 3MHHA 2VFBA 1U9QX 4FJCA 3V6EA 1HUCB 4N79A 1MIRA 1NQCA 3CBJA 2PREA 3D6SA 2HHNA 4PI3A 3WXGA 4PP2E 3H8BA 3USVA 1K3BB 1THEA 2R9MA 1TU6A 3F5VA 3PNRA 3C9EA 1TL9A 3CH2X 4DMXA 1S4VA 1YK8A 1PADA 1CQDA 3CBKA 3IEJA 1NB5A 5EF4A 4YYWA 2JQGR 2GFOA 1PPDA 2GHUA 3HHIA 2VFCA 4P6EA 6PADA 1F2BA 1QOLA 2WBFX 3I3TA 4CDFB 1AU0A 3M99A 8PCHA 4P6GA 1MDWA 1AYVA 1CSBB 2P86A 2FYEA 1ME3A 4N4ZA 1MS6A 2R9CA 4NV8A 3KFQA 2DC6A 1O0EA 3H8CA 2AUZA 4DMYA 5PADA 1XKGA 3P5UA 1E2TA 3BC3A 2AIMA 2DJGB 3ZUAA 3BOWA 1F2AA 3NHEA 2XU5A 1GX3A 2O6XA 2G8EA 3OISA 4I04A 1EWMA 1YVBA 2VHFA 2DCAA 3BPMA 1PPNA 3RVVA 1NB3A 4FIPA 2F1GA 1PPOA 1MHWA 4CZWA 5CVNB 2DZZA 1M6DA 3H6SA 4BQVA 2Y5BA 1ITOA 1DEUA 1GMYA 3IV2A 5F02A 7PCKA 1CVZA 4HWYA 3KX1A 2B1NA 4CDEB 4WA6A 1VSNA 3H89A 2R9NA 1EWPA 1W6FA 3P5VA 1YK7A 4OEMA 3TNXA 3E1ZB 2OULA 2OP3A 2YJ9A 2R6NA 2PNSA 1NPZA 2E01A 2B1MA 3MTNA 2ARYA 5JH3A 3MHSA 2E02A 1IWDA 2XU1A 2NQIA 2DCDA 3GCBA 3KW9A 4I07A 1ICFA 1DF0A 1SNKA 1BQIA 4K7CA 4NV7A 4W4UA 1GLOA 2H7JA 1Y4HA 1U5IA 3H7DA 1PCIA 3P5WA 4ZUXU 1SP4B 2FUDA 1BY8A 1FH0A 4YYQA 2R9FA 1AU3A 4BSQA 4FK5A 4PADA 1ME4A 2HD5A 1EWOA 2ACTA 5FPWA 4G54A 4MZSA 4QRGA 4PP1A 2FQ9A 5CHVA 4BPVA 3K8UA 2YJBA 3F75A 4QH6A 3KWBX 3O1GA 1ATKA 1QDQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LFY A;  2HH5 A;  3KSE A;  1PIP A;  2NQA A;  1CTE A;  1CJL A;  1PE6 A;  2G6D A;  4YYR A;  3PDF A;  3IHP A;  3K24 A;  1PXV A;  4W5C A;  1TLO A;  1KFU L;  1GEC E;  1EF7 A;  2IPP B;  4XR7 A;  3WXF A;  3PBH A;  4XUI A;  1AU2 A;  3QT4 A;  2AUX A;  1U9W A;  2YJ2 A;  3KKU A;  4YYS A;  2DZY A;  2DCB A;  2HXZ A;  3N4C A;  2FO5 A;  4YYU A;  2PAD A;  3QJ3 A;  1Q6K A;  3P5X A;  3HD3 A;  5CHT A;  2F7D A;  4YYV A;  2DC7 A;  3QSD A;  2DC9 A;  4AXL A;  3BCN A;  2JQF R;  3BPF A;  3MOR A;  5CVO B;  5K16 A;  3S3Q A;  2FTD A;  1MEM A;  2NQD B;  1KHP A;  3KWZ A;  3IMA A;  2CB5 A;  5CVM A;  3S3R A;  5EGW A;  3HWN A;  2BDL A;  1A6R A;  3RVW A;  4Q8H A;  3IUT A;  1EWL A;  2E00 A;  1F29 A;  1POP A;  3RVX A;  2NQG A;  5A24 A;  4CDC B;  3LXS A;  3N3K A;  2FRQ A;  1X9Y A;  2XU4 A;  3ERV A;  4RY2 A;  4W5B A;  2R9O A;  4I05 A;  2FT2 A;  3OF8 A;  2FRA A;  2DCC A;  2G7Y A;  4AXM A;  2Y6E A;  3CH3 X;  1CV8 A;  4YV8 A;  2AYN A;  1KXR A;  2DJF B;  1YAL A;  3OF9 A;  2E03 A;  1VJV A;  4YVA A;  1QXP A;  1Y08 A;  3IOQ A;  3K9M A;  3I06 A;  2YJ8 A;  4BS5 A;  1STF E;  1JQP A;  3WXE A;  3OVZ A;  4N8W A;  2P7U A;  4X6J A;  2C0Y A;  4CDD B;  1AIM A;  1CPJ A;  4KLB A;  1BP4 A;  1AU4 A;  2G8J A;  3OVX A;  4OEL A;  1QMY A;  3O0U A;  1F2C A;  2CIO A;  1GCB A;  3N3G A;  1ZCM A;  4BS6 A;  1NL6 A;  5JA7 A;  4X6I A;  1BGO A;  3DF0 A;  2YJC A;  1U9V A;  3HHA A;  2ATO A;  4MSX A;  4Q8G A;  3AI8 A;  4QRX A;  4X6H A;  4QBB A;  2DC8 A;  1NLJ A;  2VHS A;  3U8E A;  5J94 A;  1CS8 A;  1KFX L;  2OZ2 A;  2BDZ A;  1CB5 A;  2XU3 A;  4MZO A;  1AEC A;  3V6C A;  1PBH A;  1AYU A;  1MEG A;  2AVW A;  1ZIV A;  1YT7 A;  1KHQ A;  1PPP A;  2P0R A;  2PBH A;  1AYW A;  2AS8 A;  2AU1 A;  9PAP A;  3BWK A;  4QRV A;  3B79 A;  3PW3 A;  2AYO A;  2IBI A;  1U9X A;  3MHH A;  1U9Q X;  4FJC A;  3V6E A;  1HUC B;  4N79 A;  1MIR A;  1NQC A;  3CBJ A;  2PRE A;  3D6S A;  2HHN A;  4PI3 A;  3WXG A;  4PP2 E;  3H8B A;  3USV A;  1K3B B;  1THE A;  2R9M A;  1TU6 A;  3F5V A;  3PNR A;  3C9E A;  1TL9 A;  3CH2 X;  4DMX A;  1S4V A;  1YK8 A;  1PAD A;  1CQD A;  3CBK A;  3IEJ A;  1NB5 A;  5EF4 A;  4YYW A;  2JQG R;  2GFO A;  1PPD A;  2GHU A;  3HHI A;  4P6E A;  6PAD A;  1F2B A;  1QOL A;  2WBF X;  3I3T A;  4CDF B;  1AU0 A;  3M99 A;  8PCH A;  4P6G A;  1MDW A;  1AYV A;  1CSB B;  2P86 A;  2FYE A;  1ME3 A;  4N4Z A;  1MS6 A;  2R9C A;  3KFQ A;  2DC6 A;  1O0E A;  3H8C A;  2AUZ A;  4DMY A;  5PAD A;  1XKG A;  3P5U A;  3BC3 A;  2AIM A;  2DJG B;  3ZUA A;  3BOW A;  1F2A A;  3NHE A;  2XU5 A;  2O6X A;  2G8E A;  3OIS A;  4I04 A;  1EWM A;  1YVB A;  2VHF A;  2DCA A;  3BPM A;  1PPN A;  3RVV A;  1NB3 A;  4FIP A;  2F1G A;  1PPO A;  1MHW A;  4CZW A;  5CVN B;  2DZZ A;  1M6D A;  3H6S A;  4BQV A;  2Y5B A;  1ITO A;  1DEU A;  1GMY A;  3IV2 A;  5F02 A;  7PCK A;  1CVZ A;  4HWY A;  3KX1 A;  2B1N A;  4CDE B;  4WA6 A;  1VSN A;  3H89 A;  2R9N A;  1EWP A;  3P5V A;  1YK7 A;  4OEM A;  3TNX A;  3E1Z B;  2OUL A;  2OP3 A;  2YJ9 A;  2R6N A;  2PNS A;  1NPZ A;  2E01 A;  2B1M A;  3MTN A;  2ARY A;  5JH3 A;  3MHS A;  2E02 A;  1IWD A;  2XU1 A;  2NQI A;  2DCD A;  3GCB A;  3KW9 A;  4I07 A;  1ICF A;  1DF0 A;  1SNK A;  1BQI A;  4K7C A;  4W4U A;  1GLO A;  2H7J A;  1Y4H A;  1U5I A;  3H7D A;  1PCI A;  3P5W A;  4ZUX U;  1SP4 B;  2FUD A;  1BY8 A;  1FH0 A;  4YYQ A;  2R9F A;  1AU3 A;  4BSQ A;  4FK5 A;  4PAD A;  1ME4 A;  2HD5 A;  1EWO A;  2ACT A;  5FPW A;  4G54 A;  4MZS A;  4QRG A;  4PP1 A;  2FQ9 A;  5CHV A;  4BPV A;  3K8U A;  2YJB A;  3F75 A;  4QH6 A;  3KWB X;  3O1G A;  1ATK A;  1QDQ A; 
#chains in the Genus database with same CATH topology
 3B21 A;  3LFY A;  2HH5 A;  3KSE A;  1PIP A;  2NQA A;  1CTE A;  1CJL A;  1PE6 A;  2G6D A;  4BOQ A;  4YYR A;  3PDF A;  4MM3 B;  3IHP A;  3K24 A;  1PXV A;  4W5C A;  1TLO A;  1KFU L;  1GEC E;  1EF7 A;  2IPP B;  2J7Q C;  4XR7 A;  3WXF A;  3PBH A;  4XUI A;  1AU2 A;  3ZNH A;  3QT4 A;  2AUX A;  3PHU A;  1U9W A;  2YJ2 A;  3KKU A;  4YYS A;  2DZY A;  2DCB A;  2HXZ A;  3N4C A;  2FO5 A;  4YYU A;  2HWK A;  2PAD A;  3QJ3 A;  1Q6K A;  2JTC A;  3P5X A;  3HD3 A;  5CHT A;  2F7D A;  4YYV A;  2DC7 A;  3QSD A;  3TMP A;  2DC9 A;  4AXL A;  3BCN A;  2JQF R;  3BPF A;  3MOR A;  5CVO B;  5K16 A;  3S3Q A;  3BB7 A;  2FTD A;  5EZQ A;  1MEM A;  2NQD B;  1KHP A;  3KWZ A;  4RF1 A;  3IMA A;  2CB5 A;  5CVM A;  3S3R A;  5EGW A;  4XZX A;  3HWN A;  2BDL A;  1A6R A;  4PT5 A;  4BOZ A;  3RVW A;  2JRI A;  4Q8H A;  3IUT A;  1EWL A;  2E00 A;  1F29 A;  1POP A;  3RVX A;  2NQG A;  5A24 A;  4CDC B;  3LXS A;  3N3K A;  2FRQ A;  1X9Y A;  2XU4 A;  3ERV A;  1DKI A;  4RY2 A;  4W5B A;  2R9O A;  4I05 A;  2FT2 A;  3OF8 A;  2FRA A;  2DCC A;  2G7Y A;  4AXM A;  2Y6E A;  3CH3 X;  2BTW B;  1CV8 A;  4YV8 A;  3W31 A;  2AYN A;  1KXR A;  2DJF B;  1YAL A;  3OF9 A;  2E03 A;  3PT2 A;  1VJV A;  4YVA A;  3C0R A;  1QXP A;  1Y08 A;  3IOQ A;  3K9M A;  3I06 A;  4OVZ B;  2YJ8 A;  4BS5 A;  1STF E;  1JQP A;  3WXE A;  3OVZ A;  4N8W A;  2P7U A;  4X6J A;  2C0Y A;  4CDD B;  1AIM A;  1CPJ A;  4D8B A;  4KLB A;  1BP4 A;  1AU4 A;  2G8J A;  2AGA A;  3OVX A;  4R3D A;  3E9S A;  4OEL A;  1QMY A;  3O0U A;  1F2C A;  2CIO A;  1GCB A;  3N3G A;  1ZCM A;  4BS6 A;  1NL6 A;  5JA7 A;  4X6I A;  1BGO A;  2BU3 A;  3DF0 A;  2YJC A;  2FE8 A;  1U9V A;  3HHA A;  4RNA A;  2ATO A;  4MSX A;  4Q8G A;  3AI8 A;  4QRX A;  4X6H A;  4QBB A;  2DC8 A;  1NLJ A;  2VHS A;  4WUR A;  3U8E A;  5J94 A;  3BY4 A;  1CS8 A;  1KFX L;  4GUA A;  4D8E A;  2BTW A;  2OZ2 A;  4ZTB A;  2BDZ A;  1CB5 A;  2XU3 A;  4MZO A;  1AEC A;  3V6C A;  1PBH A;  1AYU A;  1MEG A;  2AVW A;  2J7Q A;  1ZIV A;  4RKX A;  4A5U A;  3MJ5 A;  1YT7 A;  1KHQ A;  1PPP A;  2P0R A;  3BBA A;  4IUM A;  4OVZ A;  3PHW A;  2PBH A;  1AYW A;  2AS8 A;  2AU1 A;  9PAP A;  3BWK A;  4BOS A;  4OW0 A;  4QRV A;  3B79 A;  3PW3 A;  2AYO A;  3W30 A;  2IBI A;  1U9X A;  3MHH A;  1PVJ A;  1U9Q X;  4FJC A;  3V6E A;  1HUC B;  4N79 A;  1MIR A;  1NQC A;  4MI7 A;  3CBJ A;  3PRP A;  4M0W A;  2PRE A;  3D6S A;  2HHN A;  4PI3 A;  3WXG A;  4REZ A;  4PP2 E;  3H8B A;  3USV A;  1K3B B;  1THE A;  2R9M A;  1TU6 A;  3F5V A;  3PNR A;  3C9E A;  1YZB A;  1TL9 A;  3CH2 X;  4DMX A;  1S4V A;  1YK8 A;  3RNV A;  3PHX A;  1PAD A;  1CQD A;  3CBK A;  3IEJ A;  1NB5 A;  5EF4 A;  4YYW A;  2JQG R;  2GFO A;  2UZJ A;  3OQC A;  1PPD A;  2GHU A;  3HHI A;  4P6E A;  6PAD A;  1F2B A;  1QOL A;  2WBF X;  4BOU A;  3I3T A;  4CDF B;  1AU0 A;  3M99 A;  8PCH A;  4P6G A;  1MDW A;  1AYV A;  2DOS A;  1CSB B;  2P86 A;  2FYE A;  1ME3 A;  4N4Z A;  4P16 A;  1MS6 A;  2R9C A;  5EZS A;  3KFQ A;  2DC6 A;  1O0E A;  3H8C A;  2AUZ A;  4DMY A;  5PAD A;  1XKG A;  3P5U A;  3BC3 A;  2AIM A;  3IFU A;  2DJG B;  3ZUA A;  3BOW A;  3TRK A;  1F2A A;  3NHE A;  2XU5 A;  2O6X A;  2G8E A;  3OIS A;  1EWM A;  1YVB A;  4I04 A;  2VHF A;  2DCA A;  3BPM A;  1PPN A;  3RVV A;  1NB3 A;  5JZE A;  4FIP A;  2F1G A;  1PPO A;  1MHW A;  4CZW A;  5CVN B;  5E6J A;  2DZZ A;  1M6D A;  3H6S A;  4BQV A;  2Y5B A;  1ITO A;  1DEU A;  1GMY A;  3IV2 A;  5F02 A;  7PCK A;  1CVZ A;  4HWY A;  3KX1 A;  2B1N A;  4CDE B;  4WA6 A;  1VSN A;  3H89 A;  2R9N A;  1EWP A;  3P5V A;  1YK7 A;  4OEM A;  3TNX A;  3E1Z B;  5KO3 A;  2OUL A;  2OP3 A;  2YJ9 A;  2R6N A;  2PNS A;  1NPZ A;  2E01 A;  2B1M A;  3MTN A;  4D8I A;  4BOP A;  3PSE A;  2ARY A;  5JH3 A;  3MHS A;  4IP3 A;  2E02 A;  1IWD A;  2XU1 A;  3PRM A;  2NQI A;  2DCD A;  3GCB A;  3KW9 A;  4I07 A;  1ICF A;  1DF0 A;  1SNK A;  1BQI A;  4K7C A;  4W4U A;  1GLO A;  4RF0 A;  2H7J A;  1Y4H A;  1U5I A;  3H7D A;  1PCI A;  3O65 A;  3P5W A;  4ZUX U;  1SP4 B;  2FUD A;  1BY8 A;  1FH0 A;  4YYQ A;  2R9F A;  1AU3 A;  4BSQ A;  4FK5 A;  4PAD A;  1ME4 A;  2HD5 A;  1UKF A;  1EWO A;  2ACT A;  5FPW A;  4G54 A;  4HXD B;  4MZS A;  4QRG A;  4PP1 A;  2FQ9 A;  5CHV A;  2Z84 A;  4BPV A;  3MP2 A;  3K8U A;  2YJB A;  3F75 A;  3MTV A;  4QH6 A;  3KWB X;  3O1G A;  1ATK A;  1QDQ A; 
#chains in the Genus database with same CATH homology
 3LFY A;  2HH5 A;  3KSE A;  1PIP A;  2NQA A;  1CTE A;  1CJL A;  1PE6 A;  2G6D A;  4YYR A;  3PDF A;  3IHP A;  3K24 A;  1PXV A;  4W5C A;  1TLO A;  1KFU L;  1GEC E;  1EF7 A;  2IPP B;  4XR7 A;  3WXF A;  3PBH A;  4XUI A;  1AU2 A;  3QT4 A;  2AUX A;  1U9W A;  4GUZ A;  2YJ2 A;  3KKU A;  4YYS A;  2DZY A;  2DCB A;  2HXZ A;  3N4C A;  2FO5 A;  4YYU A;  2PAD A;  3QJ3 A;  1Q6K A;  3P5X A;  3HD3 A;  5CHT A;  2F7D A;  4YYV A;  2DC7 A;  3QSD A;  2DC9 A;  4AXL A;  3BCN A;  2JQF R;  3BPF A;  3MOR A;  5CVO B;  5K16 A;  3S3Q A;  2FTD A;  1MEM A;  2NQD B;  1KHP A;  3KWZ A;  3IMA A;  2CB5 A;  5CVM A;  3S3R A;  5EGW A;  3HWN A;  2BDL A;  1A6R A;  3RVW A;  4Q8H A;  4BGF A;  3IUT A;  1EWL A;  2E00 A;  1F29 A;  1POP A;  3RVX A;  2NQG A;  5A24 A;  4CDC B;  3LXS A;  3N3K A;  2FRQ A;  1X9Y A;  2XU4 A;  3ERV A;  4RY2 A;  4W5B A;  2R9O A;  4I05 A;  2FT2 A;  3OF8 A;  2FRA A;  2DCC A;  2G7Y A;  4AXM A;  2Y6E A;  3CH3 X;  1CV8 A;  4YV8 A;  2AYN A;  1KXR A;  2DJF B;  1YAL A;  3OF9 A;  2E03 A;  1VJV A;  4YVA A;  1QXP A;  1Y08 A;  3IOQ A;  3K9M A;  3I06 A;  2YJ8 A;  4BS5 A;  1STF E;  1JQP A;  3WXE A;  3OVZ A;  4C5P A;  4N8W A;  2P7U A;  4X6J A;  2C0Y A;  4CDD B;  1AIM A;  1CPJ A;  4KLB A;  1BP4 A;  1AU4 A;  2G8J A;  3OVX A;  4OEL A;  1QMY A;  3O0U A;  1F2C A;  2CIO A;  1GCB A;  3N3G A;  1ZCM A;  4BS6 A;  1NL6 A;  5JA7 A;  4X6I A;  1BGO A;  1W5R A;  3DF0 A;  2YJC A;  1U9V A;  3HHA A;  2ATO A;  4MSX A;  2BSZ A;  3LTW A;  4Q8G A;  3AI8 A;  4QRX A;  4X6H A;  4QBB A;  2DC8 A;  1NLJ A;  2VHS A;  3U8E A;  5J94 A;  1W4T A;  1CS8 A;  1KFX L;  2OZ2 A;  2BDZ A;  1CB5 A;  2XU3 A;  4MZO A;  1AEC A;  3V6C A;  1PBH A;  1AYU A;  1MEG A;  2AVW A;  1ZIV A;  1YT7 A;  1KHQ A;  1PPP A;  2P0R A;  2PBH A;  1AYW A;  2AS8 A;  2AU1 A;  9PAP A;  3BWK A;  4QRV A;  3B79 A;  3PW3 A;  2AYO A;  2IBI A;  3D9W A;  1U9X A;  4B55 A;  3MHH A;  2VFB A;  1U9Q X;  4FJC A;  3V6E A;  1HUC B;  4N79 A;  1MIR A;  1NQC A;  3CBJ A;  2PRE A;  3D6S A;  2HHN A;  4PI3 A;  3WXG A;  4PP2 E;  3H8B A;  3USV A;  1K3B B;  1THE A;  2R9M A;  1TU6 A;  3F5V A;  3PNR A;  3C9E A;  1TL9 A;  3CH2 X;  4DMX A;  1S4V A;  1YK8 A;  1PAD A;  1CQD A;  3CBK A;  3IEJ A;  1NB5 A;  5EF4 A;  4YYW A;  2JQG R;  2GFO A;  1PPD A;  2GHU A;  3HHI A;  2VFC A;  4P6E A;  6PAD A;  1F2B A;  1QOL A;  2WBF X;  3I3T A;  4CDF B;  1AU0 A;  3M99 A;  8PCH A;  4P6G A;  1MDW A;  1AYV A;  1CSB B;  2P86 A;  2FYE A;  1ME3 A;  4N4Z A;  1MS6 A;  2R9C A;  4NV8 A;  3KFQ A;  2DC6 A;  1O0E A;  3H8C A;  2AUZ A;  4DMY A;  5PAD A;  1XKG A;  3P5U A;  1E2T A;  3BC3 A;  2AIM A;  2DJG B;  3ZUA A;  3BOW A;  1F2A A;  3NHE A;  2XU5 A;  1GX3 A;  2O6X A;  2G8E A;  3OIS A;  4I04 A;  1EWM A;  1YVB A;  2VHF A;  2DCA A;  3BPM A;  1PPN A;  3RVV A;  1NB3 A;  4FIP A;  2F1G A;  1PPO A;  1MHW A;  4CZW A;  5CVN B;  2DZZ A;  1M6D A;  3H6S A;  4BQV A;  2Y5B A;  1ITO A;  1DEU A;  1GMY A;  3IV2 A;  5F02 A;  7PCK A;  1CVZ A;  4HWY A;  3KX1 A;  2B1N A;  4CDE B;  4WA6 A;  1VSN A;  3H89 A;  2R9N A;  1EWP A;  1W6F A;  3P5V A;  1YK7 A;  4OEM A;  3TNX A;  3E1Z B;  2OUL A;  2OP3 A;  2YJ9 A;  2R6N A;  2PNS A;  1NPZ A;  2E01 A;  2B1M A;  3MTN A;  2ARY A;  5JH3 A;  3MHS A;  2E02 A;  1IWD A;  2XU1 A;  2NQI A;  2DCD A;  3GCB A;  3KW9 A;  4I07 A;  1ICF A;  1DF0 A;  1SNK A;  1BQI A;  4K7C A;  4NV7 A;  4W4U A;  1GLO A;  2H7J A;  1Y4H A;  1U5I A;  3H7D A;  1PCI A;  3P5W A;  4ZUX U;  1SP4 B;  2FUD A;  1BY8 A;  1FH0 A;  4YYQ A;  2R9F A;  1AU3 A;  4BSQ A;  4FK5 A;  4PAD A;  1ME4 A;  2HD5 A;  1EWO A;  2ACT A;  5FPW A;  4G54 A;  4MZS A;  4QRG A;  4PP1 A;  2FQ9 A;  5CHV A;  4BPV A;  3K8U A;  2YJB A;  3F75 A;  4QH6 A;  3KWB X;  3O1G A;  1ATK A;  1QDQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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