3BC3A

Exploring inhibitor binding at the s subsites of cathepsin l
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
220
structure length
214
Chain Sequence
APRSVDWREKGYVTPVKNQGQCGSWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Exploring inhibitor binding at the S' subsites of cathepsin L
pubmed doi rcsb
molecule keywords Cathepsin L heavy and light chains
molecule tags Hydrolase
source organism Homo sapiens
total genus 67
structure length 214
sequence length 220
chains with identical sequence B
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2007-11-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3bc3A00
3O0UA 1MHWA 1A6RA 2CIOA 3LXSA 2GFOA 3P5XA 3QSDA 3MHSA 3V6CA 5JA7A 4PP2E 4X6JA 3BPMA 4PI3A 4QH6A 2GHUA 2ACTA 2DCAA 3ZUAA 1XKGA 4OELA 1MDWA 1GMYA 1VSNA 3P5UA 2BDZA 1U5IA 2F1GA 4RY2A 2AS8A 5PADA 1M6DA 3H89A 1O0EA 1ZIVA 1Y08A 4XR7A 3PW3A 1ME3A 3F5VA 2NQGA 1BP4A 1QDQA 3LFYA 4DMXA 5CVNB 5EF4A 1CJLA 1AU0A 2P0RA 4HWYA 3P5VA 2R9FA 3PDFA 3H8CA 4CDDB 2YJ9A 1QMYA 5CVMA 2FQ9A 1U9XA 1GECE 3D6SA 1HUCB 1PCIA 3BC3A 2AVWA 2G6DA 2AYNA 2H7JA 3OVZA 5FPWA 1ITOA 1PIPA 2AUZA 1AYUA 4YYQA 2XU4A 4YV8A 9PAPA 2XU3A 2IPPB 2OZ2A 1FH0A 3N3KA 2AYOA 4MSXA 1Y4HA 1YK7A 4Q8HA 1PADA 3IOQA 3MORA 1NB5A 3IUTA 2YJBA 4ZUXU 1PPNA 3N3GA 4N4ZA 2IBIA 1NQCA 3IMAA 5A24A 2FRQA 2OP3A 1F2BA 1YT7A 2FRAA 5CHTA 4KLBA 3HD3A 3KWBX 5EGWA 1VJVA 2BDLA 2Y6EA 1NL6A 4BS5A 3USVA 1MEMA 1DF0A 2R6NA 2NQAA 2PADA 1AYWA 2XU5A 3HHAA 1EWPA 1MIRA 1NB3A 3H7DA 1CQDA 4FIPA 4CDEB 1PE6A 1GLOA 2PBHA 4YYWA 4BSQA 2G7YA 2ATOA 3CBJA 1AU4A 4YVAA 3KFQA 4I05A 1NLJA 1KHQA 4QRGA 3I06A 3ERVA 3OF8A 5CVOB 4MZOA 1CV8A 1KHPA 1ME4A 4DMYA 4MZSA 5JH3A 2PREA 1AU2A 2HXZA 1X9YA 2DC9A 1ICFA 3BOWA 1SNKA 1PPDA 2CB5A 3DF0A 1ZCMA 3K24A 3RVWA 1DEUA 3PBHA 4I07A 1EWLA 3M99A 3RVXA 2HHNA 1U9QX 2FT2A 2DC6A 2PNSA 4W5BA 2DC8A 4PADA 2E01A 3GCBA 5CHVA 2VHFA 1TL9A 5F02A 3WXFA 1F2CA 1BGOA 3TNXA 1K3BB 2NQDB 1CSBB 1PPPA 3KKUA 4Q8GA 2XU1A 2B1NA 1KFXL 1AECA 2FUDA 1YALA 2DCDA 1GCBA 4YYVA 4CZWA 3K8UA 1IWDA 2OULA 2ARYA 3AI8A 4K7CA 4P6EA 1CS8A 1EWMA 2P7UA 3MHHA 3K9MA 3U8EA 1CTEA 3KX1A 4FJCA 1QXPA 1AIMA 3IHPA 8PCHA 2YJCA 1S4VA 1F29A 2DCCA 2E00A 3I3TA 2JQFR 2G8JA 3H8BA 3B79A 2NQIA 3S3QA 4AXMA 4BPVA 4X6IA 3V6EA 1SP4B 3P5WA 3E1ZB 1TU6A 4I04A 1YK8A 1POPA 4YYSA 5J94A 1KXRA 2VHSA 1EWOA 1THEA 2C0YA 3RVVA 2B1MA 4YYRA 2O6XA 1CB5A 3F75A 2HD5A 2AUXA 1YVBA 3H6SA 2F7DA 2YJ8A 2DZZA 1Q6KA 3OISA 1F2AA 3C9EA 4OEMA 4P6GA 4W4UA 3CBKA 1AU3A 2DCBA 1MS6A 5K16A 1NPZA 1AYVA 1EF7A 2R9OA 1PPOA 3N4CA 3BCNA 2AIMA 1U9WA 4BQVA 3CH3X 2DJFB 3NHEA 2FO5A 3O1GA 4PP1A 4QRVA 3KWZA 3QJ3A 4BS6A 2JQGR 4YYUA 1PBHA 1U9VA 2R9MA 4AXLA 1PXVA 3OF9A 3WXEA 3BPFA 2DJGB 3HHIA 6PADA 2HH5A 1TLOA 4G54A 4X6HA 3MTNA 3QT4A 2DZYA 3IV2A 7PCKA 4QRXA 3IEJA 4CDFB 3OVXA 4FK5A 2R9CA 1JQPA 3KSEA 3HWNA 1CVZA 2WBFX 1CPJA 2AU1A 4N79A 2YJ2A 3PNRA 1STFE 2FYEA 2R9NA 4N8WA 2E02A 1ATKA 2DC7A 1BY8A 3WXGA 2P86A 3BWKA 4XUIA 4WA6A 2Y5BA 2FTDA 2G8EA 1KFUL 4QBBA 1BQIA 1MEGA 1QOLA 3KW9A 3S3RA 2E03A 4W5CA 3CH2X 4CDCB
chains in the Genus database with same CATH superfamily
3TMPA 3O0UA 1MHWA 1A6RA 2CIOA 3TRKA 2J7QC 3LXSA 2GFOA 2JTCA 3P5XA 2BTWA 3QSDA 4IP3A 3MHSA 3V6CA 5JA7A 4PP2E 4X6JA 3BPMA 4PI3A 4QH6A 2GHUA 2ACTA 2DCAA 3ZUAA 1XKGA 4OELA 1MDWA 3ZNHA 3BBAA 2AGAA 1GMYA 1VSNA 3P5UA 2BDZA 1U5IA 2F1GA 4RY2A 2AS8A 5PADA 1M6DA 3H89A 1O0EA 4D8IA 1ZIVA 1Y08A 4XR7A 3PW3A 1ME3A 3F5VA 2NQGA 1BP4A 1QDQA 3LFYA 4DMXA 5CVNB 5EF4A 1CJLA 1AU0A 2P0RA 4HWYA 3P5VA 2R9FA 3PDFA 3H8CA 4CDDB 2YJ9A 1QMYA 3PT2A 5CVMA 2DOSA 2FQ9A 4BOSA 1U9XA 1GECE 3D6SA 1HUCB 1PCIA 3BC3A 2AVWA 3MJ5A 2G6DA 5EZSA 2AYNA 2H7JA 3OVZA 2FE8A 5FPWA 1ITOA 3PHWA 1PIPA 3IFUA 2AUZA 1AYUA 4YYQA 2XU4A 4YV8A 9PAPA 2XU3A 2IPPB 2OZ2A 1FH0A 3N3KA 2AYOA 4MSXA 1Y4HA 1YK7A 4Q8HA 1PADA 3IOQA 3MORA 1NB5A 4D8BA 3PSEA 3IUTA 2YJBA 4ZUXU 1PPNA 3N3GA 4N4ZA 5JZEA 2IBIA 1NQCA 3IMAA 2UZJA 5A24A 2FRQA 2OP3A 1F2BA 1YT7A 2FRAA 5CHTA 4KLBA 4BOUA 3HD3A 3KWBX 5EGWA 4ZTBA 1VJVA 4OVZB 2BDLA 2Y6EA 1NL6A 4BS5A 3USVA 1MEMA 1DF0A 2Z84A 2R6NA 2NQAA 2PADA 4R3DA 1AYWA 3PHUA 2XU5A 3HHAA 1EWPA 3RNVA 1MIRA 1NB3A 3H7DA 1CQDA 4FIPA 4CDEB 1PE6A 1GLOA 3E9SA 2PBHA 4YYWA 4BSQA 2G7YA 2ATOA 3CBJA 1AU4A 4YVAA 3KFQA 4I05A 1NLJA 1KHQA 4QRGA 3I06A 3ERVA 3OF8A 3MP2A 1YZBA 5CVOB 4MZOA 1CV8A 1KHPA 1ME4A 4DMYA 4MZSA 5JH3A 4MI7A 2PREA 1AU2A 2HXZA 1X9YA 2DC9A 1ICFA 3BOWA 1SNKA 1PPDA 2CB5A 3DF0A 4RF1A 1ZCMA 3K24A 4M0WA 3RVWA 1DEUA 3PBHA 4I07A 1EWLA 3M99A 3RVXA 2HHNA 1U9QX 2FT2A 2DC6A 2PNSA 4W5BA 2DC8A 2JRIA 4PADA 2E01A 3GCBA 4PT5A 5CHVA 2VHFA 1TL9A 5F02A 3WXFA 1F2CA 1BGOA 3TNXA 1K3BB 2NQDB 1CSBB 1PPPA 3KKUA 4XZXA 4Q8GA 2XU1A 2B1NA 1KFXL 1AECA 2FUDA 5E6JA 1PVJA 1YALA 2DCDA 1GCBA 4YYVA 4CZWA 3K8UA 1IWDA 2OULA 4BOQA 2ARYA 3AI8A 4K7CA 5KO3A 4P6EA 1CS8A 1EWMA 2P7UA 3MHHA 3PRMA 3K9MA 3U8EA 3BY4A 1CTEA 3KX1A 4FJCA 1QXPA 5EZQA 1AIMA 3IHPA 8PCHA 2YJCA 1S4VA 1F29A 2DCCA 2E00A 3I3TA 2JQFR 2G8JA 2BU3A 3H8BA 3B79A 2NQIA 3S3QA 4AXMA 4BPVA 4X6IA 3PRPA 3V6EA 1SP4B 3P5WA 3E1ZB 1TU6A 4I04A 1YK8A 4IUMA 1POPA 4YYSA 5J94A 1KXRA 2VHSA 1EWOA 1THEA 2C0YA 3RVVA 4REZA 2B1MA 4RNAA 4YYRA 2O6XA 4RKXA 1CB5A 4GUAA 3F75A 2HD5A 2AUXA 4OVZA 1YVBA 3H6SA 2F7DA 2YJ8A 3B21A 2DZZA 3W31A 1Q6KA 3OISA 1F2AA 3C9EA 4OEMA 4P6GA 3PHXA 4W4UA 2J7QA 3CBKA 1AU3A 2DCBA 1MS6A 5K16A 4WURA 1NPZA 4BOZA 1AYVA 1EF7A 2R9OA 1PPOA 3N4CA 3BCNA 1DKIA 2AIMA 1U9WA 3C0RA 1UKFA 4BQVA 3CH3X 2DJFB 3NHEA 2FO5A 3O1GA 4PP1A 4QRVA 3KWZA 3QJ3A 4BS6A 2JQGR 4YYUA 1PBHA 3BB7A 3MTVA 1U9VA 2R9MA 4AXLA 1PXVA 3OF9A 3WXEA 3BPFA 2DJGB 4P16A 3HHIA 6PADA 2HH5A 1TLOA 4G54A 4X6HA 3MTNA 3QT4A 2BTWB 2HWKA 2DZYA 3IV2A 7PCKA 4QRXA 3IEJA 4CDFB 4D8EA 4RF0A 3OVXA 4FK5A 2R9CA 1JQPA 3KSEA 3HWNA 3W30A 3OQCA 1CVZA 2WBFX 3O65A 1CPJA 2AU1A 4N79A 4A5UA 2YJ2A 4MM3B 3PNRA 1STFE 2FYEA 2R9NA 4N8WA 2E02A 1ATKA 4HXDB 4BOPA 2DC7A 1BY8A 3WXGA 2P86A 3BWKA 4XUIA 4WA6A 2Y5BA 2FTDA 2G8EA 1KFUL 4QBBA 1BQIA 1MEGA 1QOLA 3KW9A 3S3RA 2E03A 4W5CA 4OW0A 3CH2X 4CDCB
chains in the Genus database with same CATH topology
4NV7A 3O0UA 1MHWA 1A6RA 2CIOA 3LXSA 2GFOA 3P5XA 3QSDA 3MHSA 3V6CA 5JA7A 4PP2E 4X6JA 3BPMA 4PI3A 4QH6A 2GHUA 2ACTA 2DCAA 3ZUAA 1XKGA 4OELA 1MDWA 4NV8A 3LTWA 1GMYA 1VSNA 3P5UA 2BDZA 1U5IA 2F1GA 4RY2A 2AS8A 5PADA 1M6DA 3H89A 1O0EA 1ZIVA 1Y08A 4XR7A 3PW3A 1ME3A 3F5VA 2NQGA 1BP4A 1QDQA 3LFYA 4DMXA 5CVNB 5EF4A 1CJLA 1AU0A 2P0RA 4HWYA 3P5VA 2R9FA 3PDFA 3H8CA 4CDDB 2YJ9A 1QMYA 5CVMA 2FQ9A 1U9XA 1GECE 3D6SA 1HUCB 1PCIA 3BC3A 2AVWA 2G6DA 2AYNA 2H7JA 3OVZA 5FPWA 1ITOA 1PIPA 2AUZA 1AYUA 4YYQA 2XU4A 4YV8A 9PAPA 2XU3A 2IPPB 2OZ2A 1FH0A 3N3KA 2AYOA 4MSXA 1GX3A 1Y4HA 1YK7A 4Q8HA 1PADA 3IOQA 3MORA 1NB5A 3IUTA 2YJBA 4ZUXU 1PPNA 3N3GA 4N4ZA 2IBIA 1NQCA 3IMAA 1W5RA 5A24A 2FRQA 2OP3A 1F2BA 1YT7A 2FRAA 5CHTA 4KLBA 3HD3A 3KWBX 5EGWA 1VJVA 2BDLA 2Y6EA 1NL6A 4BS5A 3USVA 1MEMA 1DF0A 2R6NA 2NQAA 2PADA 1AYWA 2XU5A 3HHAA 1EWPA 1MIRA 1NB3A 3H7DA 1CQDA 4FIPA 4CDEB 1PE6A 1GLOA 2PBHA 4YYWA 4BSQA 2G7YA 2ATOA 3CBJA 1AU4A 4YVAA 3KFQA 4I05A 1NLJA 1KHQA 4QRGA 3I06A 3ERVA 3OF8A 5CVOB 4MZOA 1CV8A 1W6FA 1KHPA 1ME4A 4DMYA 4MZSA 5JH3A 2PREA 1AU2A 2HXZA 1X9YA 2BSZA 2DC9A 3D9WA 1ICFA 3BOWA 1SNKA 1PPDA 2CB5A 3DF0A 1ZCMA 3K24A 3RVWA 1DEUA 3PBHA 4I07A 1EWLA 3M99A 3RVXA 1W4TA 2HHNA 1U9QX 2FT2A 2DC6A 2PNSA 4W5BA 2DC8A 2VFBA 4PADA 4B55A 2E01A 3GCBA 5CHVA 2VHFA 1TL9A 5F02A 3WXFA 1F2CA 1BGOA 3TNXA 1K3BB 2NQDB 1CSBB 1PPPA 3KKUA 4Q8GA 2XU1A 4GUZA 2B1NA 1KFXL 1AECA 2FUDA 1YALA 2DCDA 1GCBA 4YYVA 4CZWA 1E2TA 3K8UA 1IWDA 2OULA 2ARYA 3AI8A 4K7CA 4P6EA 1CS8A 1EWMA 2P7UA 3MHHA 3K9MA 3U8EA 1CTEA 3KX1A 4FJCA 1QXPA 1AIMA 3IHPA 8PCHA 2YJCA 1S4VA 1F29A 2DCCA 2E00A 3I3TA 2JQFR 2G8JA 4C5PA 3H8BA 3B79A 2NQIA 3S3QA 4AXMA 4BPVA 4X6IA 3V6EA 1SP4B 3P5WA 3E1ZB 1TU6A 4I04A 1YK8A 1POPA 4YYSA 5J94A 1KXRA 2VHSA 1EWOA 1THEA 2C0YA 3RVVA 2B1MA 4YYRA 2O6XA 1CB5A 3F75A 2HD5A 2AUXA 1YVBA 2VFCA 3H6SA 2F7DA 2YJ8A 2DZZA 1Q6KA 3OISA 1F2AA 3C9EA 4OEMA 4P6GA 4W4UA 3CBKA 1AU3A 2DCBA 1MS6A 5K16A 1NPZA 1AYVA 1EF7A 2R9OA 1PPOA 3N4CA 3BCNA 2AIMA 1U9WA 4BQVA 3CH3X 2DJFB 3NHEA 2FO5A 3O1GA 4PP1A 4QRVA 3KWZA 3QJ3A 4BS6A 2JQGR 4YYUA 1PBHA 1U9VA 2R9MA 4AXLA 1PXVA 3OF9A 3WXEA 3BPFA 2DJGB 3HHIA 6PADA 2HH5A 1TLOA 4G54A 4X6HA 3MTNA 3QT4A 2DZYA 3IV2A 7PCKA 4QRXA 3IEJA 4CDFB 3OVXA 4FK5A 2R9CA 1JQPA 3KSEA 3HWNA 1CVZA 2WBFX 1CPJA 2AU1A 4N79A 2YJ2A 3PNRA 1STFE 2FYEA 2R9NA 4BGFA 4N8WA 2E02A 1ATKA 2DC7A 1BY8A 3WXGA 2P86A 3BWKA 4XUIA 4WA6A 2Y5BA 2FTDA 2G8EA 1KFUL 4QBBA 1BQIA 1MEGA 1QOLA 3KW9A 3S3RA 2E03A 4W5CA 3CH2X 4CDCB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3O0U A;  1MHW A;  1A6R A;  2CIO A;  3LXS A;  2GFO A;  3P5X A;  3QSD A;  3MHS A;  3V6C A;  5JA7 A;  4PP2 E;  4X6J A;  3BPM A;  4PI3 A;  4QH6 A;  2GHU A;  2ACT A;  2DCA A;  3ZUA A;  1XKG A;  4OEL A;  1MDW A;  1GMY A;  1VSN A;  3P5U A;  2BDZ A;  1U5I A;  2F1G A;  4RY2 A;  2AS8 A;  5PAD A;  1M6D A;  3H89 A;  1O0E A;  1ZIV A;  1Y08 A;  4XR7 A;  3PW3 A;  1ME3 A;  3F5V A;  2NQG A;  1BP4 A;  1QDQ A;  3LFY A;  4DMX A;  5CVN B;  5EF4 A;  1CJL A;  1AU0 A;  2P0R A;  4HWY A;  3P5V A;  2R9F A;  3PDF A;  3H8C A;  4CDD B;  2YJ9 A;  1QMY A;  5CVM A;  2FQ9 A;  1U9X A;  1GEC E;  3D6S A;  1HUC B;  1PCI A;  3BC3 A;  2AVW A;  2G6D A;  2AYN A;  2H7J A;  3OVZ A;  5FPW A;  1ITO A;  1PIP A;  2AUZ A;  1AYU A;  4YYQ A;  2XU4 A;  4YV8 A;  9PAP A;  2XU3 A;  2IPP B;  2OZ2 A;  1FH0 A;  3N3K A;  2AYO A;  4MSX A;  1Y4H A;  1YK7 A;  4Q8H A;  1PAD A;  3IOQ A;  3MOR A;  1NB5 A;  3IUT A;  2YJB A;  4ZUX U;  1PPN A;  3N3G A;  4N4Z A;  2IBI A;  1NQC A;  3IMA A;  5A24 A;  2FRQ A;  2OP3 A;  1F2B A;  1YT7 A;  2FRA A;  5CHT A;  4KLB A;  3HD3 A;  3KWB X;  5EGW A;  1VJV A;  2BDL A;  2Y6E A;  1NL6 A;  4BS5 A;  3USV A;  1MEM A;  1DF0 A;  2R6N A;  2NQA A;  2PAD A;  1AYW A;  2XU5 A;  3HHA A;  1EWP A;  1MIR A;  1NB3 A;  3H7D A;  1CQD A;  4FIP A;  4CDE B;  1PE6 A;  1GLO A;  2PBH A;  4YYW A;  4BSQ A;  2G7Y A;  2ATO A;  3CBJ A;  1AU4 A;  4YVA A;  3KFQ A;  4I05 A;  1NLJ A;  1KHQ A;  4QRG A;  3I06 A;  3ERV A;  3OF8 A;  5CVO B;  4MZO A;  1CV8 A;  1KHP A;  1ME4 A;  4DMY A;  4MZS A;  5JH3 A;  2PRE A;  1AU2 A;  2HXZ A;  1X9Y A;  2DC9 A;  1ICF A;  3BOW A;  1SNK A;  1PPD A;  2CB5 A;  3DF0 A;  1ZCM A;  3K24 A;  3RVW A;  1DEU A;  3PBH A;  4I07 A;  1EWL A;  3M99 A;  3RVX A;  2HHN A;  1U9Q X;  2FT2 A;  2DC6 A;  2PNS A;  4W5B A;  2DC8 A;  4PAD A;  2E01 A;  3GCB A;  5CHV A;  2VHF A;  1TL9 A;  5F02 A;  3WXF A;  1F2C A;  1BGO A;  3TNX A;  1K3B B;  2NQD B;  1CSB B;  1PPP A;  3KKU A;  4Q8G A;  2XU1 A;  2B1N A;  1KFX L;  1AEC A;  2FUD A;  1YAL A;  2DCD A;  1GCB A;  4YYV A;  4CZW A;  3K8U A;  1IWD A;  2OUL A;  2ARY A;  3AI8 A;  4K7C A;  4P6E A;  1CS8 A;  1EWM A;  2P7U A;  3MHH A;  3K9M A;  3U8E A;  1CTE A;  3KX1 A;  4FJC A;  1QXP A;  1AIM A;  3IHP A;  8PCH A;  2YJC A;  1S4V A;  1F29 A;  2DCC A;  2E00 A;  3I3T A;  2JQF R;  2G8J A;  3H8B A;  3B79 A;  2NQI A;  3S3Q A;  4AXM A;  4BPV A;  4X6I A;  3V6E A;  1SP4 B;  3P5W A;  3E1Z B;  1TU6 A;  4I04 A;  1YK8 A;  1POP A;  4YYS A;  5J94 A;  1KXR A;  2VHS A;  1EWO A;  1THE A;  2C0Y A;  3RVV A;  2B1M A;  4YYR A;  2O6X A;  1CB5 A;  3F75 A;  2HD5 A;  2AUX A;  1YVB A;  3H6S A;  2F7D A;  2YJ8 A;  2DZZ A;  1Q6K A;  3OIS A;  1F2A A;  3C9E A;  4OEM A;  4P6G A;  4W4U A;  3CBK A;  1AU3 A;  2DCB A;  1MS6 A;  5K16 A;  1NPZ A;  1AYV A;  1EF7 A;  2R9O A;  1PPO A;  3N4C A;  3BCN A;  2AIM A;  1U9W A;  4BQV A;  3CH3 X;  2DJF B;  3NHE A;  2FO5 A;  3O1G A;  4PP1 A;  4QRV A;  3KWZ A;  3QJ3 A;  4BS6 A;  2JQG R;  4YYU A;  1PBH A;  1U9V A;  2R9M A;  4AXL A;  1PXV A;  3OF9 A;  3WXE A;  3BPF A;  2DJG B;  3HHI A;  6PAD A;  2HH5 A;  1TLO A;  4G54 A;  4X6H A;  3MTN A;  3QT4 A;  2DZY A;  3IV2 A;  7PCK A;  4QRX A;  3IEJ A;  4CDF B;  3OVX A;  4FK5 A;  2R9C A;  1JQP A;  3KSE A;  3HWN A;  1CVZ A;  2WBF X;  1CPJ A;  2AU1 A;  4N79 A;  2YJ2 A;  3PNR A;  1STF E;  2FYE A;  2R9N A;  4N8W A;  2E02 A;  1ATK A;  2DC7 A;  1BY8 A;  3WXG A;  2P86 A;  3BWK A;  4XUI A;  4WA6 A;  2Y5B A;  2FTD A;  2G8E A;  1KFU L;  4QBB A;  1BQI A;  1MEG A;  1QOL A;  3KW9 A;  3S3R A;  2E03 A;  4W5C A;  3CH2 X;  4CDC B; 
#chains in the Genus database with same CATH topology
 3TMP A;  3O0U A;  1MHW A;  1A6R A;  2CIO A;  3TRK A;  2J7Q C;  3LXS A;  2GFO A;  2JTC A;  3P5X A;  2BTW A;  3QSD A;  4IP3 A;  3MHS A;  3V6C A;  5JA7 A;  4PP2 E;  4X6J A;  3BPM A;  4PI3 A;  4QH6 A;  2GHU A;  2ACT A;  2DCA A;  3ZUA A;  1XKG A;  4OEL A;  1MDW A;  3ZNH A;  3BBA A;  2AGA A;  1GMY A;  1VSN A;  3P5U A;  2BDZ A;  1U5I A;  2F1G A;  4RY2 A;  2AS8 A;  5PAD A;  1M6D A;  3H89 A;  1O0E A;  4D8I A;  1ZIV A;  1Y08 A;  4XR7 A;  3PW3 A;  1ME3 A;  3F5V A;  2NQG A;  1BP4 A;  1QDQ A;  3LFY A;  4DMX A;  5CVN B;  5EF4 A;  1CJL A;  1AU0 A;  2P0R A;  4HWY A;  3P5V A;  2R9F A;  3PDF A;  3H8C A;  4CDD B;  2YJ9 A;  1QMY A;  3PT2 A;  5CVM A;  2DOS A;  2FQ9 A;  4BOS A;  1U9X A;  1GEC E;  3D6S A;  1HUC B;  1PCI A;  3BC3 A;  2AVW A;  3MJ5 A;  2G6D A;  5EZS A;  2AYN A;  2H7J A;  3OVZ A;  2FE8 A;  5FPW A;  1ITO A;  3PHW A;  1PIP A;  3IFU A;  2AUZ A;  1AYU A;  4YYQ A;  2XU4 A;  4YV8 A;  9PAP A;  2XU3 A;  2IPP B;  2OZ2 A;  1FH0 A;  3N3K A;  2AYO A;  4MSX A;  1Y4H A;  1YK7 A;  4Q8H A;  1PAD A;  3IOQ A;  3MOR A;  1NB5 A;  4D8B A;  3PSE A;  3IUT A;  2YJB A;  4ZUX U;  1PPN A;  3N3G A;  4N4Z A;  5JZE A;  2IBI A;  1NQC A;  3IMA A;  2UZJ A;  5A24 A;  2FRQ A;  2OP3 A;  1F2B A;  1YT7 A;  2FRA A;  5CHT A;  4KLB A;  4BOU A;  3HD3 A;  3KWB X;  5EGW A;  4ZTB A;  1VJV A;  4OVZ B;  2BDL A;  2Y6E A;  1NL6 A;  4BS5 A;  3USV A;  1MEM A;  1DF0 A;  2Z84 A;  2R6N A;  2NQA A;  2PAD A;  4R3D A;  1AYW A;  3PHU A;  2XU5 A;  3HHA A;  1EWP A;  3RNV A;  1MIR A;  1NB3 A;  3H7D A;  1CQD A;  4FIP A;  4CDE B;  1PE6 A;  1GLO A;  3E9S A;  2PBH A;  4YYW A;  4BSQ A;  2G7Y A;  2ATO A;  3CBJ A;  1AU4 A;  4YVA A;  3KFQ A;  4I05 A;  1NLJ A;  1KHQ A;  4QRG A;  3I06 A;  3ERV A;  3OF8 A;  3MP2 A;  1YZB A;  5CVO B;  4MZO A;  1CV8 A;  1KHP A;  1ME4 A;  4DMY A;  4MZS A;  5JH3 A;  4MI7 A;  2PRE A;  1AU2 A;  2HXZ A;  1X9Y A;  2DC9 A;  1ICF A;  3BOW A;  1SNK A;  1PPD A;  2CB5 A;  3DF0 A;  4RF1 A;  1ZCM A;  3K24 A;  4M0W A;  3RVW A;  1DEU A;  3PBH A;  4I07 A;  1EWL A;  3M99 A;  3RVX A;  2HHN A;  1U9Q X;  2FT2 A;  2DC6 A;  2PNS A;  4W5B A;  2DC8 A;  2JRI A;  4PAD A;  2E01 A;  3GCB A;  4PT5 A;  5CHV A;  2VHF A;  1TL9 A;  5F02 A;  3WXF A;  1F2C A;  1BGO A;  3TNX A;  1K3B B;  2NQD B;  1CSB B;  1PPP A;  3KKU A;  4XZX A;  4Q8G A;  2XU1 A;  2B1N A;  1KFX L;  1AEC A;  2FUD A;  5E6J A;  1PVJ A;  1YAL A;  2DCD A;  1GCB A;  4YYV A;  4CZW A;  3K8U A;  1IWD A;  2OUL A;  4BOQ A;  2ARY A;  3AI8 A;  4K7C A;  5KO3 A;  4P6E A;  1CS8 A;  1EWM A;  2P7U A;  3MHH A;  3PRM A;  3K9M A;  3U8E A;  3BY4 A;  1CTE A;  3KX1 A;  4FJC A;  1QXP A;  5EZQ A;  1AIM A;  3IHP A;  8PCH A;  2YJC A;  1S4V A;  1F29 A;  2DCC A;  2E00 A;  3I3T A;  2JQF R;  2G8J A;  2BU3 A;  3H8B A;  3B79 A;  2NQI A;  3S3Q A;  4AXM A;  4BPV A;  4X6I A;  3PRP A;  3V6E A;  1SP4 B;  3P5W A;  3E1Z B;  1TU6 A;  4I04 A;  1YK8 A;  4IUM A;  1POP A;  4YYS A;  5J94 A;  1KXR A;  2VHS A;  1EWO A;  1THE A;  2C0Y A;  3RVV A;  4REZ A;  2B1M A;  4RNA A;  4YYR A;  2O6X A;  4RKX A;  1CB5 A;  4GUA A;  3F75 A;  2HD5 A;  2AUX A;  4OVZ A;  1YVB A;  3H6S A;  2F7D A;  2YJ8 A;  3B21 A;  2DZZ A;  3W31 A;  1Q6K A;  3OIS A;  1F2A A;  3C9E A;  4OEM A;  4P6G A;  3PHX A;  4W4U A;  2J7Q A;  3CBK A;  1AU3 A;  2DCB A;  1MS6 A;  5K16 A;  4WUR A;  1NPZ A;  4BOZ A;  1AYV A;  1EF7 A;  2R9O A;  1PPO A;  3N4C A;  3BCN A;  1DKI A;  2AIM A;  1U9W A;  3C0R A;  1UKF A;  4BQV A;  3CH3 X;  2DJF B;  3NHE A;  2FO5 A;  3O1G A;  4PP1 A;  4QRV A;  3KWZ A;  3QJ3 A;  4BS6 A;  2JQG R;  4YYU A;  1PBH A;  3BB7 A;  3MTV A;  1U9V A;  2R9M A;  4AXL A;  1PXV A;  3OF9 A;  3WXE A;  3BPF A;  2DJG B;  4P16 A;  3HHI A;  6PAD A;  2HH5 A;  1TLO A;  4G54 A;  4X6H A;  3MTN A;  3QT4 A;  2BTW B;  2HWK A;  2DZY A;  3IV2 A;  7PCK A;  4QRX A;  3IEJ A;  4CDF B;  4D8E A;  4RF0 A;  3OVX A;  4FK5 A;  2R9C A;  1JQP A;  3KSE A;  3HWN A;  3W30 A;  3OQC A;  1CVZ A;  2WBF X;  3O65 A;  1CPJ A;  2AU1 A;  4N79 A;  4A5U A;  2YJ2 A;  4MM3 B;  3PNR A;  1STF E;  2FYE A;  2R9N A;  4N8W A;  2E02 A;  1ATK A;  4HXD B;  4BOP A;  2DC7 A;  1BY8 A;  3WXG A;  2P86 A;  3BWK A;  4XUI A;  4WA6 A;  2Y5B A;  2FTD A;  2G8E A;  1KFU L;  4QBB A;  1BQI A;  1MEG A;  1QOL A;  3KW9 A;  3S3R A;  2E03 A;  4W5C A;  4OW0 A;  3CH2 X;  4CDC B; 
#chains in the Genus database with same CATH homology
 4NV7 A;  3O0U A;  1MHW A;  1A6R A;  2CIO A;  3LXS A;  2GFO A;  3P5X A;  3QSD A;  3MHS A;  3V6C A;  5JA7 A;  4PP2 E;  4X6J A;  3BPM A;  4PI3 A;  4QH6 A;  2GHU A;  2ACT A;  2DCA A;  3ZUA A;  1XKG A;  4OEL A;  1MDW A;  4NV8 A;  3LTW A;  1GMY A;  1VSN A;  3P5U A;  2BDZ A;  1U5I A;  2F1G A;  4RY2 A;  2AS8 A;  5PAD A;  1M6D A;  3H89 A;  1O0E A;  1ZIV A;  1Y08 A;  4XR7 A;  3PW3 A;  1ME3 A;  3F5V A;  2NQG A;  1BP4 A;  1QDQ A;  3LFY A;  4DMX A;  5CVN B;  5EF4 A;  1CJL A;  1AU0 A;  2P0R A;  4HWY A;  3P5V A;  2R9F A;  3PDF A;  3H8C A;  4CDD B;  2YJ9 A;  1QMY A;  5CVM A;  2FQ9 A;  1U9X A;  1GEC E;  3D6S A;  1HUC B;  1PCI A;  3BC3 A;  2AVW A;  2G6D A;  2AYN A;  2H7J A;  3OVZ A;  5FPW A;  1ITO A;  1PIP A;  2AUZ A;  1AYU A;  4YYQ A;  2XU4 A;  4YV8 A;  9PAP A;  2XU3 A;  2IPP B;  2OZ2 A;  1FH0 A;  3N3K A;  2AYO A;  4MSX A;  1GX3 A;  1Y4H A;  1YK7 A;  4Q8H A;  1PAD A;  3IOQ A;  3MOR A;  1NB5 A;  3IUT A;  2YJB A;  4ZUX U;  1PPN A;  3N3G A;  4N4Z A;  2IBI A;  1NQC A;  3IMA A;  1W5R A;  5A24 A;  2FRQ A;  2OP3 A;  1F2B A;  1YT7 A;  2FRA A;  5CHT A;  4KLB A;  3HD3 A;  3KWB X;  5EGW A;  1VJV A;  2BDL A;  2Y6E A;  1NL6 A;  4BS5 A;  3USV A;  1MEM A;  1DF0 A;  2R6N A;  2NQA A;  2PAD A;  1AYW A;  2XU5 A;  3HHA A;  1EWP A;  1MIR A;  1NB3 A;  3H7D A;  1CQD A;  4FIP A;  4CDE B;  1PE6 A;  1GLO A;  2PBH A;  4YYW A;  4BSQ A;  2G7Y A;  2ATO A;  3CBJ A;  1AU4 A;  4YVA A;  3KFQ A;  4I05 A;  1NLJ A;  1KHQ A;  4QRG A;  3I06 A;  3ERV A;  3OF8 A;  5CVO B;  4MZO A;  1CV8 A;  1W6F A;  1KHP A;  1ME4 A;  4DMY A;  4MZS A;  5JH3 A;  2PRE A;  1AU2 A;  2HXZ A;  1X9Y A;  2BSZ A;  2DC9 A;  3D9W A;  1ICF A;  3BOW A;  1SNK A;  1PPD A;  2CB5 A;  3DF0 A;  1ZCM A;  3K24 A;  3RVW A;  1DEU A;  3PBH A;  4I07 A;  1EWL A;  3M99 A;  3RVX A;  1W4T A;  2HHN A;  1U9Q X;  2FT2 A;  2DC6 A;  2PNS A;  4W5B A;  2DC8 A;  2VFB A;  4PAD A;  4B55 A;  2E01 A;  3GCB A;  5CHV A;  2VHF A;  1TL9 A;  5F02 A;  3WXF A;  1F2C A;  1BGO A;  3TNX A;  1K3B B;  2NQD B;  1CSB B;  1PPP A;  3KKU A;  4Q8G A;  2XU1 A;  4GUZ A;  2B1N A;  1KFX L;  1AEC A;  2FUD A;  1YAL A;  2DCD A;  1GCB A;  4YYV A;  4CZW A;  1E2T A;  3K8U A;  1IWD A;  2OUL A;  2ARY A;  3AI8 A;  4K7C A;  4P6E A;  1CS8 A;  1EWM A;  2P7U A;  3MHH A;  3K9M A;  3U8E A;  1CTE A;  3KX1 A;  4FJC A;  1QXP A;  1AIM A;  3IHP A;  8PCH A;  2YJC A;  1S4V A;  1F29 A;  2DCC A;  2E00 A;  3I3T A;  2JQF R;  2G8J A;  4C5P A;  3H8B A;  3B79 A;  2NQI A;  3S3Q A;  4AXM A;  4BPV A;  4X6I A;  3V6E A;  1SP4 B;  3P5W A;  3E1Z B;  1TU6 A;  4I04 A;  1YK8 A;  1POP A;  4YYS A;  5J94 A;  1KXR A;  2VHS A;  1EWO A;  1THE A;  2C0Y A;  3RVV A;  2B1M A;  4YYR A;  2O6X A;  1CB5 A;  3F75 A;  2HD5 A;  2AUX A;  1YVB A;  2VFC A;  3H6S A;  2F7D A;  2YJ8 A;  2DZZ A;  1Q6K A;  3OIS A;  1F2A A;  3C9E A;  4OEM A;  4P6G A;  4W4U A;  3CBK A;  1AU3 A;  2DCB A;  1MS6 A;  5K16 A;  1NPZ A;  1AYV A;  1EF7 A;  2R9O A;  1PPO A;  3N4C A;  3BCN A;  2AIM A;  1U9W A;  4BQV A;  3CH3 X;  2DJF B;  3NHE A;  2FO5 A;  3O1G A;  4PP1 A;  4QRV A;  3KWZ A;  3QJ3 A;  4BS6 A;  2JQG R;  4YYU A;  1PBH A;  1U9V A;  2R9M A;  4AXL A;  1PXV A;  3OF9 A;  3WXE A;  3BPF A;  2DJG B;  3HHI A;  6PAD A;  2HH5 A;  1TLO A;  4G54 A;  4X6H A;  3MTN A;  3QT4 A;  2DZY A;  3IV2 A;  7PCK A;  4QRX A;  3IEJ A;  4CDF B;  3OVX A;  4FK5 A;  2R9C A;  1JQP A;  3KSE A;  3HWN A;  1CVZ A;  2WBF X;  1CPJ A;  2AU1 A;  4N79 A;  2YJ2 A;  3PNR A;  1STF E;  2FYE A;  2R9N A;  4BGF A;  4N8W A;  2E02 A;  1ATK A;  2DC7 A;  1BY8 A;  3WXG A;  2P86 A;  3BWK A;  4XUI A;  4WA6 A;  2Y5B A;  2FTD A;  2G8E A;  1KFU L;  4QBB A;  1BQI A;  1MEG A;  1QOL A;  3KW9 A;  3S3R A;  2E03 A;  4W5C A;  3CH2 X;  4CDC B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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