3PT2A

Structure of a viral otu domain protease bound to ubiquitin
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
164
structure length
164
Chain Sequence
PGMDFLRSLDWTQVIAGQYVSNPRFNISDYFEIVRQPGDGNCFYHSIAELTMPNKTDHSYHYIKRLTESAARKYYQEEPEARLVGLSLEDYLKRMLSDNEWGSTLEASMLAKEMGITIIIWTVAASDEVEAGIKFGDGDVFTAVNLLHSGQTHFDALRILPQFE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease.
pubmed doi rcsb
molecule keywords RNA polymerase
molecule tags Hydrolase/protein binding
source organism Crimean-congo hemorrhagic fever virus
total genus 46
structure length 164
sequence length 164
ec nomenclature
pdb deposition date 2010-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02338 OTU OTU-like cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.80 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cathepsin B; Chain A 3pt2A00
3TMPA 3C0RA 3PHUA 4HXDB 5JZEA 3ZNHA 3PRPA 4BOSA 4BOZA 3PRMA 3PSEA 3BY4A 4BOPA 3PHXA 4BOQA 3PHWA 4BOUA 3PT2A
chains in the Genus database with same CATH superfamily
2DOSA 4MZSA 2G6DA 3HHAA 1Q6KA 3RVWA 3BBAA 3USVA 5JH3A 2FRQA 3P5WA 4OVZB 5EF4A 3K8UA 4BS6A 5EZSA 2HD5A 3O0UA 3PW3A 2WBFX 3HHIA 4RNAA 2H7JA 4P16A 4X6HA 3MJ5A 3KW9A 2P0RA 4IP3A 4QRGA 1Y4HA 1IWDA 3QSDA 2AUXA 1S4VA 1ATKA 1PADA 2AVWA 1KFXL 4BS5A 3MTVA 4D8IA 2G7YA 3PBHA 1MHWA 1TU6A 4HWYA 4QBBA 4YYSA 2PBHA 3TRKA 1YVBA 2DZYA 1PE6A 1SNKA 2OULA 1PIPA 2BDZA 2E00A 2YJBA 3ZNHA 1YK8A 3V6CA 4AXMA 1PCIA 4XR7A 1AU0A 1PPPA 4WURA 5F02A 2P86A 5CVMA 3AI8A 2FRAA 1ICFA 1PVJA 2DJGB 3PHWA 1EWPA 3TMPA 2ARYA 3BCNA 3E9SA 3I3TA 5K16A 4M0WA 1KHQA 4N8WA 3IV2A 1KFUL 9PAPA 1MEMA 2DC8A 1KHPA 1NB3A 3QJ3A 3IFUA 4HXDB 3PRPA 1U9QX 1Y08A 5KO3A 3MP2A 2B1MA 3BB7A 2XU1A 2O6XA 3MORA 2E01A 4CDCB 3MTNA 1F2CA 1CB5A 1X9YA 2ACTA 4BSQA 1MEGA 4YV8A 2ATOA 6PADA 3WXEA 3BWKA 3N4CA 2GHUA 2DC7A 4MZOA 2FT2A 2PREA 1PPDA 1ME3A 3RVVA 2NQAA 1QMYA 4W4UA 3B79A 4W5CA 4YYRA 3O65A 2CIOA 2OP3A 1AU4A 8PCHA 1JQPA 1BGOA 4RKXA 5J94A 2XU4A 1F2AA 3W31A 4W5BA 2F1GA 4MM3B 1UKFA 1NB5A 4CZWA 4I04A 3F75A 4D8EA 2HXZA 4PP1A 2BTWA 3H8CA 4R3DA 2C0YA 5EZQA 3P5VA 2JQGR 5CVOB 3TNXA 3ERVA 1MIRA 2G8JA 1DKIA 1CV8A 2GFOA 3O1GA 3KKUA 1NQCA 1A6RA 3E1ZB 4YVAA 4BPVA 3KWBX 1U9XA 3OISA 1KXRA 1YALA 3F5VA 4PT5A 2NQDB 2Y6EA 1AYVA 5E6JA 2YJ9A 2FUDA 3NHEA 3MHHA 4MI7A 3PNRA 2DC6A 1NL6A 4A5UA 4FK5A 4YYVA 1CJLA 1PPNA 3KWZA 3M99A 4X6JA 4BOUA 4CDDB 2FE8A 3H6SA 3RVXA 1AIMA 2DCCA 1F29A 4XUIA 4RY2A 1QXPA 3W30A 3KSEA 1THEA 1GECE 5FPWA 3B21A 2AIMA 2FTDA 4AXLA 2BTWB 1VSNA 1QDQA 5EGWA 1M6DA 1XKGA 3LXSA 3IEJA 2AYOA 1BP4A 1YZBA 3HWNA 4FJCA 1CSBB 1EF7A 1CS8A 2XU5A 3BY4A 1DEUA 3D6SA 1EWOA 4QRXA 1AYWA 1AECA 1U9VA 3LFYA 2R9FA 2YJ2A 1FH0A 4IUMA 2R9NA 3P5UA 4BOSA 4WA6A 3N3GA 4BOPA 1HUCB 1GCBA 2BDLA 3BPMA 1NPZA 2DCAA 3QT4A 1GMYA 2VHSA 3I06A 2R9CA 2HWKA 1U9WA 1EWLA 1PBHA 2YJ8A 4K7CA 4QH6A 3H8BA 3IMAA 2AYNA 4ZTBA 4N4ZA 1BY8A 4BQVA 1MS6A 3PSEA 2G8EA 3IOQA 2DZZA 5A24A 2FO5A 3V6EA 2DC9A 3P5XA 4I07A 1U5IA 2FQ9A 1BQIA 2AGAA 3PHXA 3KX1A 5JA7A 3IUTA 3K9MA 2DCDA 2HHNA 3CH3X 4GUAA 4XZXA 2PADA 4REZA 3C0RA 2BU3A 1ITOA 4DMXA 4BOQA 3ZUAA 3WXGA 2J7QC 3RNVA 1F2BA 4PP2E 2R9OA 5CVNB 1K3BB 1NLJA 2Y5BA 4YYUA 5CHTA 1ME4A 1EWMA 2NQIA 1QOLA 2XU3A 2E03A 4PI3A 4DMYA 4ZUXU 2OZ2A 4X6IA 2AS8A 5PADA 1CTEA 1O0EA 1AU3A 1YK7A 2IPPB 2FYEA 3BPFA 2DJFB 2B1NA 2P7UA 5JZEA 3KFQA 3CBJA 4RF0A 3PHUA 4KLBA 3IHPA 2DCBA 4Q8GA 3K24A 1TLOA 4BOZA 1CPJA 2UZJA 1GLOA 1STFE 1ZCMA 4P6GA 3OVZA 4I05A 1VJVA 3U8EA 7PCKA 1AU2A 1MDWA 2PNSA 4CDFB 1PPOA 5CHVA 4YYQA 4QRVA 4CDEB 2J7QA 1CQDA 2JTCA 3BOWA 4MSXA 3OF8A 4OVZA 1YT7A 3PRMA 3GCBA 3BC3A 1DF0A 3N3KA 3CBKA 3H89A 3WXFA 4P6EA 2E02A 4YYWA 4G54A 2AUZA 3OVXA 3PDFA 2AU1A 2Z84A 4OW0A 1SP4B 3S3RA 4PADA 3HD3A 4RF1A 1PXVA 4OEMA 2R9MA 2NQGA 2YJCA 2JQFR 4FIPA 1TL9A 4OELA 2HH5A 3OF9A 2IBIA 2F7DA 2JRIA 3DF0A 4Q8HA 3S3QA 2CB5A 3CH2X 4N79A 3PT2A 4D8BA 1AYUA 3OQCA 2VHFA 1CVZA 1ZIVA 3H7DA 1POPA 3C9EA 3MHSA 2R6NA
chains in the Genus database with same CATH topology
1YZBA 2DOSA 3O65A 3BBAA 4OVZB 3BY4A 5JZEA 4RKXA 5EZSA 4RF0A 4IUMA 3PHUA 4RNAA 3W31A 4BOSA 4P16A 4BOPA 3MJ5A 4IP3A 4MM3B 1UKFA 4BOZA 2UZJA 2HWKA 3MTVA 4D8IA 4D8EA 2BTWA 4R3DA 3TRKA 4ZTBA 5EZQA 3ZNHA 1DKIA 3PSEA 2J7QA 2JTCA 4OVZA 3PRMA 4WURA 2AGAA 1PVJA 3PHXA 3PHWA 3TMPA 4PT5A 3E9SA 5E6JA 4GUAA 4M0WA 4MI7A 4XZXA 2Z84A 4OW0A 4A5UA 4RF1A 4BOUA 4REZA 3C0RA 2BU3A 2FE8A 3IFUA 4HXDB 3PRPA 5KO3A 3MP2A 3BB7A 4BOQA 2JRIA 2J7QC 3RNVA 3PT2A 3W30A 4D8BA 3B21A 2BTWB 3OQCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TMP A;  3C0R A;  3PHU A;  4HXD B;  5JZE A;  3ZNH A;  3PRP A;  4BOS A;  4BOZ A;  3PRM A;  3PSE A;  3BY4 A;  4BOP A;  3PHX A;  4BOQ A;  3PHW A;  4BOU A;  3PT2 A; 
#chains in the Genus database with same CATH topology
 2DOS A;  4MZS A;  2G6D A;  3HHA A;  1Q6K A;  3RVW A;  3BBA A;  3USV A;  5JH3 A;  2FRQ A;  3P5W A;  4OVZ B;  5EF4 A;  3K8U A;  4BS6 A;  5EZS A;  2HD5 A;  3O0U A;  3PW3 A;  2WBF X;  3HHI A;  4RNA A;  2H7J A;  4P16 A;  4X6H A;  3MJ5 A;  3KW9 A;  2P0R A;  4IP3 A;  4QRG A;  1Y4H A;  1IWD A;  3QSD A;  2AUX A;  1S4V A;  1ATK A;  1PAD A;  2AVW A;  1KFX L;  4BS5 A;  3MTV A;  4D8I A;  2G7Y A;  3PBH A;  1MHW A;  1TU6 A;  4HWY A;  4QBB A;  4YYS A;  2PBH A;  3TRK A;  1YVB A;  2DZY A;  1PE6 A;  1SNK A;  2OUL A;  1PIP A;  2BDZ A;  2E00 A;  2YJB A;  3ZNH A;  1YK8 A;  3V6C A;  4AXM A;  1PCI A;  4XR7 A;  1AU0 A;  1PPP A;  4WUR A;  5F02 A;  2P86 A;  5CVM A;  3AI8 A;  2FRA A;  1ICF A;  1PVJ A;  2DJG B;  3PHW A;  1EWP A;  3TMP A;  2ARY A;  3BCN A;  3E9S A;  3I3T A;  5K16 A;  4M0W A;  1KHQ A;  4N8W A;  3IV2 A;  1KFU L;  9PAP A;  1MEM A;  2DC8 A;  1KHP A;  1NB3 A;  3QJ3 A;  3IFU A;  4HXD B;  3PRP A;  1U9Q X;  1Y08 A;  5KO3 A;  3MP2 A;  2B1M A;  3BB7 A;  2XU1 A;  2O6X A;  3MOR A;  2E01 A;  4CDC B;  3MTN A;  1F2C A;  1CB5 A;  1X9Y A;  2ACT A;  4BSQ A;  1MEG A;  4YV8 A;  2ATO A;  6PAD A;  3WXE A;  3BWK A;  3N4C A;  2GHU A;  2DC7 A;  4MZO A;  2FT2 A;  2PRE A;  1PPD A;  1ME3 A;  3RVV A;  2NQA A;  1QMY A;  4W4U A;  3B79 A;  4W5C A;  4YYR A;  3O65 A;  2CIO A;  2OP3 A;  1AU4 A;  8PCH A;  1JQP A;  1BGO A;  4RKX A;  5J94 A;  2XU4 A;  1F2A A;  3W31 A;  4W5B A;  2F1G A;  4MM3 B;  1UKF A;  1NB5 A;  4CZW A;  4I04 A;  3F75 A;  4D8E A;  2HXZ A;  4PP1 A;  2BTW A;  3H8C A;  4R3D A;  2C0Y A;  5EZQ A;  3P5V A;  2JQG R;  5CVO B;  3TNX A;  3ERV A;  1MIR A;  2G8J A;  1DKI A;  1CV8 A;  2GFO A;  3O1G A;  3KKU A;  1NQC A;  1A6R A;  3E1Z B;  4YVA A;  4BPV A;  3KWB X;  1U9X A;  3OIS A;  1KXR A;  1YAL A;  3F5V A;  4PT5 A;  2NQD B;  2Y6E A;  1AYV A;  5E6J A;  2YJ9 A;  2FUD A;  3NHE A;  3MHH A;  4MI7 A;  3PNR A;  2DC6 A;  1NL6 A;  4A5U A;  4FK5 A;  4YYV A;  1CJL A;  1PPN A;  3KWZ A;  3M99 A;  4X6J A;  4BOU A;  4CDD B;  2FE8 A;  3H6S A;  3RVX A;  1AIM A;  2DCC A;  1F29 A;  4XUI A;  4RY2 A;  1QXP A;  3W30 A;  3KSE A;  1THE A;  1GEC E;  5FPW A;  3B21 A;  2AIM A;  2FTD A;  4AXL A;  2BTW B;  1VSN A;  1QDQ A;  5EGW A;  1M6D A;  1XKG A;  3LXS A;  3IEJ A;  2AYO A;  1BP4 A;  1YZB A;  3HWN A;  4FJC A;  1CSB B;  1EF7 A;  1CS8 A;  2XU5 A;  3BY4 A;  1DEU A;  3D6S A;  1EWO A;  4QRX A;  1AYW A;  1AEC A;  1U9V A;  3LFY A;  2R9F A;  2YJ2 A;  1FH0 A;  4IUM A;  2R9N A;  3P5U A;  4BOS A;  4WA6 A;  3N3G A;  4BOP A;  1HUC B;  1GCB A;  2BDL A;  3BPM A;  1NPZ A;  2DCA A;  3QT4 A;  1GMY A;  2VHS A;  3I06 A;  2R9C A;  2HWK A;  1U9W A;  1EWL A;  1PBH A;  2YJ8 A;  4K7C A;  4QH6 A;  3H8B A;  3IMA A;  2AYN A;  4ZTB A;  4N4Z A;  1BY8 A;  4BQV A;  1MS6 A;  3PSE A;  2G8E A;  3IOQ A;  2DZZ A;  5A24 A;  2FO5 A;  3V6E A;  2DC9 A;  3P5X A;  4I07 A;  1U5I A;  2FQ9 A;  1BQI A;  2AGA A;  3PHX A;  3KX1 A;  5JA7 A;  3IUT A;  3K9M A;  2DCD A;  2HHN A;  3CH3 X;  4GUA A;  4XZX A;  2PAD A;  4REZ A;  3C0R A;  2BU3 A;  1ITO A;  4DMX A;  4BOQ A;  3ZUA A;  3WXG A;  2J7Q C;  3RNV A;  1F2B A;  4PP2 E;  2R9O A;  5CVN B;  1K3B B;  1NLJ A;  2Y5B A;  4YYU A;  5CHT A;  1ME4 A;  1EWM A;  2NQI A;  1QOL A;  2XU3 A;  2E03 A;  4PI3 A;  4DMY A;  4ZUX U;  2OZ2 A;  4X6I A;  2AS8 A;  5PAD A;  1CTE A;  1O0E A;  1AU3 A;  1YK7 A;  2IPP B;  2FYE A;  3BPF A;  2DJF B;  2B1N A;  2P7U A;  5JZE A;  3KFQ A;  3CBJ A;  4RF0 A;  3PHU A;  4KLB A;  3IHP A;  2DCB A;  4Q8G A;  3K24 A;  1TLO A;  4BOZ A;  1CPJ A;  2UZJ A;  1GLO A;  1STF E;  1ZCM A;  4P6G A;  3OVZ A;  4I05 A;  1VJV A;  3U8E A;  7PCK A;  1AU2 A;  1MDW A;  2PNS A;  4CDF B;  1PPO A;  5CHV A;  4YYQ A;  4QRV A;  4CDE B;  2J7Q A;  1CQD A;  2JTC A;  3BOW A;  4MSX A;  3OF8 A;  4OVZ A;  1YT7 A;  3PRM A;  3GCB A;  3BC3 A;  1DF0 A;  3N3K A;  3CBK A;  3H89 A;  3WXF A;  4P6E A;  2E02 A;  4YYW A;  4G54 A;  2AUZ A;  3OVX A;  3PDF A;  2AU1 A;  2Z84 A;  4OW0 A;  1SP4 B;  3S3R A;  4PAD A;  3HD3 A;  4RF1 A;  1PXV A;  4OEM A;  2R9M A;  2NQG A;  2YJC A;  2JQF R;  4FIP A;  1TL9 A;  4OEL A;  2HH5 A;  3OF9 A;  2IBI A;  2F7D A;  2JRI A;  3DF0 A;  4Q8H A;  3S3Q A;  2CB5 A;  3CH2 X;  4N79 A;  3PT2 A;  4D8B A;  1AYU A;  3OQC A;  2VHF A;  1CVZ A;  1ZIV A;  3H7D A;  1POP A;  3C9E A;  3MHS A;  2R6N A; 
#chains in the Genus database with same CATH homology
 1YZB A;  2DOS A;  3O65 A;  3BBA A;  4OVZ B;  3BY4 A;  5JZE A;  4RKX A;  5EZS A;  4RF0 A;  4IUM A;  3PHU A;  4RNA A;  3W31 A;  4BOS A;  4P16 A;  4BOP A;  3MJ5 A;  4IP3 A;  4MM3 B;  1UKF A;  4BOZ A;  2UZJ A;  2HWK A;  3MTV A;  4D8I A;  4D8E A;  2BTW A;  4R3D A;  3TRK A;  4ZTB A;  5EZQ A;  3ZNH A;  1DKI A;  3PSE A;  2J7Q A;  2JTC A;  4OVZ A;  3PRM A;  4WUR A;  2AGA A;  1PVJ A;  3PHX A;  3PHW A;  3TMP A;  4PT5 A;  3E9S A;  5E6J A;  4GUA A;  4M0W A;  4MI7 A;  4XZX A;  2Z84 A;  4OW0 A;  4A5U A;  4RF1 A;  4BOU A;  4REZ A;  3C0R A;  2BU3 A;  2FE8 A;  3IFU A;  4HXD B;  3PRP A;  5KO3 A;  3MP2 A;  3BB7 A;  4BOQ A;  2JRI A;  2J7Q C;  3RNV A;  3PT2 A;  3W30 A;  4D8B A;  3B21 A;  2BTW B;  3OQC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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