4HWYA

Trypanosoma brucei procathepsin b solved from 40 fs free-electron laser pulse data by serial femtosecond x-ray crystallography
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
314
structure length
308
Chain Sequence
EDAPVLSKAFVDRVNRLNRGIWKAKYDGVMQNITLREAKRLNGVIKILPKRRFTEEEARAPLPSSFDSAEAWPNCPTIPQIADQSACGSCWAVAAASAMSDRFCTMGGVQDVHISAGDLLACCSDCGDGCNGGDPDRAWAYFSSTGLVSDYCQPYPFPHCSHHSKSKNGYPPCSQFNFDTPKCNYTCDDPTIPVVNYRSWTSYALQGEDDYMRELFFRGPFEVAFDVYEDFIAYNSGVYHHVSGQYLGGHAVRLVGWGTSNGVPYWKIANSWNTEWGMDGYFLIRRGSSECGIEDGGSAGIPLAPNTA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Cysteine peptidase C (CPC)
publication title Natively inhibited Trypanosoma brucei cathepsin B structure determined by using an X-ray laser.
pubmed doi rcsb
source organism Trypanosoma brucei brucei treu927
total genus 98
structure length 308
sequence length 314
ec nomenclature ec 3.4.22.-:
pdb deposition date 2012-11-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 4hwyA00
3IV2A 4W5BA 3RVVA 4QRGA 1A6RA 4FJCA 3D6SA 2DC7A 4AXLA 3AI8A 3N3GA 2HH5A 4CDFB 1F2AA 1AECA 4W5CA 3F5VA 2G6DA 4FK5A 4CDCB 3LFYA 1QMYA 1KXRA 4YYUA 8PCHA 2AYOA 2YJ2A 1DEUA 3BC3A 1NB5A 2JQFR 2P86A 1PADA 1KHPA 2R9MA 1NLJA 1PPOA 3BWKA 3HHIA 2AUZA 4W4UA 1NPZA 1BP4A 3PW3A 1PCIA 1THEA 4MZOA 2WBFX 2FO5A 2R9FA 2G8JA 3I3TA 1U5IA 2R6NA 2GFOA 1VSNA 1QDQA 3RVXA 3BPFA 4P6EA 2BDLA 5A24A 3PDFA 4PP1A 3MHHA 4AXMA 4Q8HA 2FT2A 3HWNA 1ATKA 3P5XA 1MHWA 3TNXA 1KHQA 2FRAA 4YV8A 2FQ9A 1S4VA 3B79A 4PADA 3H8CA 4ZUXU 5EGWA 2NQGA 3QJ3A 5F02A 1F29A 2XU5A 4BPVA 2XU3A 5J94A 4YYRA 4K7CA 1CVZA 4N79A 4CDEB 3U8EA 2AU1A 3PBHA 3CH2X 1MDWA 3ERVA 3CBJA 3S3RA 2P7UA 2G8EA 3HHAA 4YVAA 2E02A 4I07A 4CDDB 2AIMA 5JA7A 3S3QA 2OP3A 1X9YA 1CS8A 2YJBA 1AU0A 3OVZA 4P6GA 1ZCMA 2PNSA 1FH0A 3N4CA 3DF0A 1AU4A 3M99A 1BQIA 3K8UA 2G7YA 1U9WA 1CQDA 1YK8A 1TLOA 2YJ8A 3IEJA 2XU1A 3P5VA 3E1ZB 4BS5A 5EF4A 2VHFA 4XR7A 2HD5A 2IBIA 4DMYA 1U9QX 2E01A 4PP2E 2CIOA 4CZWA 2HXZA 3V6EA 1EWMA 3KW9A 4X6HA 2DC6A 3O1GA 4QBBA 1M6DA 1CTEA 4BSQA 2BDZA 3H7DA 2Y5BA 1GCBA 2O6XA 2OULA 3MHSA 3OF8A 3C9EA 4MZSA 2NQDB 1QOLA 2XU4A 1U9XA 1Y08A 6PADA 1PPPA 1YALA 1PIPA 4X6IA 2CB5A 4QRVA 2C0YA 2AYNA 1MS6A 3KFQA 1CPJA 3WXFA 1NL6A 2R9OA 9PAPA 4YYWA 1GMYA 4YYQA 4WA6A 1AIMA 5CVMA 2ATOA 3H6SA 4N4ZA 5PADA 2B1MA 4N8WA 2HHNA 4OEMA 3IUTA 3P5UA 1PPNA 2IPPB 1HUCB 5CVNB 2PBHA 2DJGB 4HWYA 2E00A 3USVA 4YYSA 1IWDA 1GLOA 3QSDA 1QXPA 3K24A 2GHUA 2FRQA 3BCNA 3MTNA 3MORA 5K16A 1BGOA 2DCAA 2DZZA 4MSXA 2YJ9A 1XKGA 3GCBA 4FIPA 2F1GA 3P5WA 4BQVA 1YT7A 3IOQA 2NQIA 1F2CA 1EWOA 2YJCA 3BPMA 1F2BA 2NQAA 1K3BB 2R9CA 3KWZA 3LXSA 1SNKA 1EWLA 1Q6KA 2DJFB 2VHSA 5CVOB 4DMXA 2JQGR 2P0RA 2FTDA 4RY2A 4X6JA 2AS8A 1VJVA 4XUIA 3KKUA 1EWPA 3IMAA 2F7DA 1AYWA 1PBHA 7PCKA 1AU2A 1AYVA 2OZ2A 3BOWA 3F75A 4PI3A 1CSBB 3RVWA 3QT4A 4QH6A 2Y6EA 4KLBA 4BS6A 2AUXA 1KFXL 3WXGA 2DC8A 2R9NA 1NB3A 1STFE 2DCDA 2FYEA 2B1NA 1ME4A 1BY8A 2E03A 3V6CA 3CH3X 4QRXA 3OVXA 5JH3A 1GECE 1PPDA 4I04A 3PNRA 3K9MA 4G54A 1O0EA 4I05A 1DF0A 1YVBA 1MEMA 1ME3A 2FUDA 1PE6A 1JQPA 3KSEA 1Y4HA 3CBKA 2DCBA 1POPA 2DCCA 1AU3A 4OELA 1ZIVA 1TU6A 1ITOA 3I06A 1CJLA 3OF9A 1CB5A 1PXVA 5CHTA 1ICFA 1MIRA 4Q8GA 3HD3A 3H89A 1EF7A 3N3KA 5CHVA 3OISA 5FPWA 1KFUL 3NHEA 4YYVA 2DZYA 1AYUA 3KWBX 2AVWA 1YK7A 2PREA 3IHPA 3H8BA 1NQCA 1MEGA 2ARYA 1CV8A 3WXEA 2ACTA 1SP4B 1U9VA 3O0UA 2DC9A 2H7JA 2PADA 3KX1A 3ZUAA 1TL9A
chains in the Genus database with same CATH superfamily
3IV2A 4W5BA 3RVVA 4QRGA 3C0RA 1A6RA 4RNAA 4FJCA 3D6SA 2DC7A 2HWKA 4AXLA 3AI8A 3N3GA 4OW0A 4RF1A 2HH5A 2FE8A 4CDFB 1F2AA 1AECA 4W5CA 3F5VA 2G6DA 4FK5A 4CDCB 3LFYA 4BOZA 1QMYA 1KXRA 4YYUA 8PCHA 2AYOA 2YJ2A 1DEUA 3BC3A 1NB5A 2JQFR 2P86A 1PADA 1KHPA 2R9MA 4BOQA 1NLJA 1PPOA 3BWKA 3HHIA 4OVZA 2AUZA 4W4UA 1NPZA 4BOSA 1BP4A 3PW3A 1PCIA 3BB7A 1THEA 4MZOA 2WBFX 2FO5A 2R9FA 2G8JA 3ZNHA 3I3TA 1U5IA 2R6NA 2GFOA 1VSNA 1QDQA 3RVXA 3MP2A 3BPFA 4P6EA 2BDLA 5A24A 3PDFA 4PP1A 3MHHA 4AXMA 4Q8HA 2FT2A 3HWNA 1ATKA 3P5XA 1MHWA 4PT5A 4BOPA 3TNXA 1KHQA 2FRAA 4YV8A 2BTWA 2FQ9A 1S4VA 3B79A 4PADA 3H8CA 4ZUXU 5EGWA 2NQGA 3QJ3A 5F02A 1F29A 2XU5A 4BPVA 2XU3A 5J94A 4YYRA 4K7CA 1CVZA 4N79A 4XZXA 4CDEB 3U8EA 2AU1A 4HXDB 3PBHA 3CH2X 1MDWA 3ERVA 3PHUA 3CBJA 2J7QC 3S3RA 2P7UA 2G8EA 3HHAA 4YVAA 2E02A 2JTCA 4I07A 4CDDB 2AIMA 5JA7A 3S3QA 2OP3A 1X9YA 1CS8A 2YJBA 1AU0A 3OVZA 4P6GA 1ZCMA 4IP3A 2PNSA 1FH0A 3N4CA 3DF0A 1AU4A 3M99A 1BQIA 3K8UA 2G7YA 1U9WA 1CQDA 1YK8A 1TLOA 2YJ8A 3IEJA 2XU1A 3MTVA 3P5VA 3E1ZB 1PVJA 4BS5A 4GUAA 1DKIA 5EF4A 2VHFA 4XR7A 2HD5A 2IBIA 4DMYA 1U9QX 2E01A 4PP2E 2CIOA 4CZWA 2HXZA 3V6EA 1EWMA 3KW9A 4X6HA 2DC6A 3O1GA 4QBBA 1M6DA 1CTEA 4BSQA 2BDZA 3H7DA 2Y5BA 1GCBA 2O6XA 2OULA 3MHSA 3OF8A 3C9EA 4MZSA 3MJ5A 3PT2A 3IFUA 2NQDB 1QOLA 2XU4A 1U9XA 1Y08A 6PADA 1PPPA 1YALA 1PIPA 4OVZB 4X6IA 2CB5A 3TRKA 4QRVA 5E6JA 2C0YA 2AYNA 1MS6A 3KFQA 1CPJA 3WXFA 1NL6A 2R9OA 4WURA 9PAPA 4YYWA 1GMYA 4YYQA 4WA6A 1AIMA 3PRMA 5CVMA 2ATOA 3H6SA 2UZJA 4N4ZA 5PADA 2B1MA 4N8WA 2HHNA 3OQCA 4OEMA 3IUTA 3P5UA 1PPNA 2IPPB 1HUCB 5CVNB 2PBHA 2DJGB 4HWYA 2E00A 3USVA 4YYSA 1IWDA 1GLOA 3QSDA 1QXPA 3K24A 2GHUA 4MI7A 2FRQA 3BCNA 3MTNA 3MORA 5K16A 3PRPA 1BGOA 2DCAA 2DZZA 2JRIA 4MSXA 5KO3A 2YJ9A 1XKGA 3W30A 3GCBA 4FIPA 2F1GA 3P5WA 4BQVA 1YT7A 3IOQA 2NQIA 1F2CA 1EWOA 2YJCA 3BPMA 1F2BA 4RKXA 5JZEA 2NQAA 3O65A 1K3BB 2R9CA 3KWZA 3LXSA 1SNKA 4R3DA 1EWLA 1Q6KA 4IUMA 2DJFB 2VHSA 5CVOB 4DMXA 2JQGR 2P0RA 2FTDA 4RY2A 2AGAA 4X6JA 3PHWA 2AS8A 1VJVA 5EZQA 4XUIA 3KKUA 1EWPA 3IMAA 3B21A 2F7DA 3W31A 1AYWA 1PBHA 7PCKA 1AU2A 1AYVA 2OZ2A 3BOWA 3F75A 4PI3A 5EZSA 1CSBB 3RVWA 3QT4A 4QH6A 2Y6EA 4KLBA 4BS6A 2AUXA 1KFXL 3WXGA 2DC8A 2R9NA 4A5UA 4REZA 1NB3A 1STFE 1YZBA 2DCDA 2FYEA 2B1NA 1ME4A 1BY8A 2E03A 3V6CA 3CH3X 4QRXA 3OVXA 5JH3A 4D8IA 3PSEA 1GECE 1PPDA 4I04A 4MM3B 3PHXA 3PNRA 3K9MA 3RNVA 4G54A 1O0EA 2Z84A 4I05A 1DF0A 1YVBA 1MEMA 1ME3A 2FUDA 2DOSA 4RF0A 1PE6A 3TMPA 1JQPA 3KSEA 1Y4HA 3CBKA 2DCBA 1POPA 4P16A 2DCCA 1AU3A 4OELA 1ZIVA 1TU6A 2BTWB 1ITOA 3BY4A 3I06A 3E9SA 1CJLA 2BU3A 3OF9A 1CB5A 1PXVA 3BBAA 5CHTA 1ICFA 4D8EA 1MIRA 4BOUA 4Q8GA 1UKFA 3HD3A 3H89A 2J7QA 1EF7A 3N3KA 4D8BA 5CHVA 3OISA 5FPWA 4M0WA 1KFUL 3NHEA 4YYVA 2DZYA 1AYUA 3KWBX 2AVWA 1YK7A 2PREA 3IHPA 3H8BA 1NQCA 4ZTBA 1MEGA 2ARYA 1CV8A 3WXEA 2ACTA 1SP4B 1U9VA 3O0UA 2DC9A 2H7JA 2PADA 3KX1A 3ZUAA 1TL9A
chains in the Genus database with same CATH topology
3IV2A 4W5BA 3RVVA 4QRGA 1A6RA 4FJCA 3D6SA 2DC7A 4AXLA 3AI8A 3N3GA 2HH5A 4CDFB 1F2AA 1AECA 4W5CA 3F5VA 2G6DA 4FK5A 4CDCB 3LFYA 1QMYA 1KXRA 4YYUA 8PCHA 2AYOA 2YJ2A 1DEUA 3BC3A 1NB5A 2JQFR 2P86A 1PADA 1KHPA 2R9MA 1GX3A 1NLJA 1PPOA 3BWKA 3HHIA 2BSZA 2AUZA 2VFCA 4W4UA 1NPZA 1BP4A 3PW3A 1PCIA 1THEA 4MZOA 2WBFX 2FO5A 2R9FA 2G8JA 3I3TA 1U5IA 2R6NA 2GFOA 1VSNA 1QDQA 3RVXA 3BPFA 4P6EA 2BDLA 5A24A 3PDFA 4PP1A 3MHHA 4AXMA 4Q8HA 2FT2A 3HWNA 2VFBA 1ATKA 3P5XA 1MHWA 3TNXA 1KHQA 2FRAA 4YV8A 2FQ9A 1W5RA 1S4VA 3B79A 4PADA 3H8CA 4ZUXU 5EGWA 2NQGA 3QJ3A 5F02A 1F29A 2XU5A 4BPVA 2XU3A 5J94A 4YYRA 4K7CA 1CVZA 4N79A 4CDEB 3U8EA 2AU1A 3PBHA 3CH2X 1MDWA 3ERVA 3CBJA 3S3RA 2P7UA 2G8EA 3HHAA 4YVAA 2E02A 1W4TA 4I07A 4CDDB 2AIMA 5JA7A 3S3QA 3D9WA 2OP3A 1X9YA 1CS8A 2YJBA 1AU0A 3OVZA 4P6GA 1ZCMA 2PNSA 1FH0A 3N4CA 3DF0A 1AU4A 3M99A 1BQIA 3K8UA 2G7YA 1U9WA 4B55A 1CQDA 1YK8A 1TLOA 2YJ8A 3IEJA 2XU1A 3P5VA 3E1ZB 4BS5A 5EF4A 2VHFA 4XR7A 2HD5A 2IBIA 4DMYA 1U9QX 1W6FA 2E01A 4PP2E 2CIOA 4CZWA 2HXZA 3V6EA 1EWMA 3KW9A 4X6HA 2DC6A 3O1GA 4QBBA 1M6DA 1CTEA 4BSQA 2BDZA 3H7DA 2Y5BA 1GCBA 2O6XA 2OULA 3MHSA 3OF8A 3C9EA 4MZSA 2NQDB 1QOLA 2XU4A 1U9XA 1Y08A 6PADA 1PPPA 1YALA 1PIPA 4X6IA 2CB5A 4QRVA 1E2TA 2C0YA 2AYNA 1MS6A 3KFQA 1CPJA 3WXFA 1NL6A 2R9OA 9PAPA 4C5PA 4YYWA 1GMYA 4YYQA 4WA6A 1AIMA 5CVMA 2ATOA 3H6SA 4N4ZA 5PADA 2B1MA 4N8WA 2HHNA 4OEMA 3IUTA 3P5UA 1PPNA 2IPPB 1HUCB 5CVNB 2PBHA 2DJGB 4HWYA 2E00A 3USVA 4YYSA 1IWDA 1GLOA 3QSDA 1QXPA 3K24A 2GHUA 2FRQA 3BCNA 3MTNA 3MORA 5K16A 1BGOA 2DCAA 2DZZA 4MSXA 2YJ9A 1XKGA 3GCBA 4FIPA 2F1GA 3P5WA 4BQVA 1YT7A 3IOQA 2NQIA 1F2CA 1EWOA 2YJCA 3BPMA 1F2BA 2NQAA 4BGFA 1K3BB 2R9CA 3KWZA 3LXSA 1SNKA 1EWLA 1Q6KA 2DJFB 2VHSA 5CVOB 4DMXA 2JQGR 2P0RA 2FTDA 4RY2A 4X6JA 2AS8A 1VJVA 4XUIA 3KKUA 1EWPA 3IMAA 2F7DA 1AYWA 1PBHA 7PCKA 1AU2A 1AYVA 2OZ2A 3BOWA 3F75A 4PI3A 1CSBB 3RVWA 3QT4A 4QH6A 4GUZA 2Y6EA 4KLBA 4BS6A 2AUXA 1KFXL 4NV7A 3WXGA 2DC8A 2R9NA 1NB3A 1STFE 2DCDA 2FYEA 2B1NA 3LTWA 1ME4A 1BY8A 2E03A 3V6CA 3CH3X 4QRXA 3OVXA 5JH3A 1GECE 1PPDA 4I04A 3PNRA 3K9MA 4G54A 1O0EA 4I05A 1DF0A 1YVBA 1MEMA 4NV8A 1ME3A 2FUDA 1PE6A 1JQPA 3KSEA 1Y4HA 3CBKA 2DCBA 1POPA 2DCCA 1AU3A 4OELA 1ZIVA 1TU6A 1ITOA 3I06A 1CJLA 3OF9A 1CB5A 1PXVA 5CHTA 1ICFA 1MIRA 4Q8GA 3HD3A 3H89A 1EF7A 3N3KA 5CHVA 3OISA 5FPWA 1KFUL 3NHEA 4YYVA 2DZYA 1AYUA 3KWBX 2AVWA 1YK7A 2PREA 3IHPA 3H8BA 1NQCA 1MEGA 2ARYA 1CV8A 3WXEA 2ACTA 1SP4B 1U9VA 3O0UA 2DC9A 2H7JA 2PADA 3KX1A 3ZUAA 1TL9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IV2 A;  4W5B A;  3RVV A;  4QRG A;  1A6R A;  4FJC A;  3D6S A;  2DC7 A;  4AXL A;  3AI8 A;  3N3G A;  2HH5 A;  4CDF B;  1F2A A;  1AEC A;  4W5C A;  3F5V A;  2G6D A;  4FK5 A;  4CDC B;  3LFY A;  1QMY A;  1KXR A;  4YYU A;  8PCH A;  2AYO A;  2YJ2 A;  1DEU A;  3BC3 A;  1NB5 A;  2JQF R;  2P86 A;  1PAD A;  1KHP A;  2R9M A;  1NLJ A;  1PPO A;  3BWK A;  3HHI A;  2AUZ A;  4W4U A;  1NPZ A;  1BP4 A;  3PW3 A;  1PCI A;  1THE A;  4MZO A;  2WBF X;  2FO5 A;  2R9F A;  2G8J A;  3I3T A;  1U5I A;  2R6N A;  2GFO A;  1VSN A;  1QDQ A;  3RVX A;  3BPF A;  4P6E A;  2BDL A;  5A24 A;  3PDF A;  4PP1 A;  3MHH A;  4AXM A;  4Q8H A;  2FT2 A;  3HWN A;  1ATK A;  3P5X A;  1MHW A;  3TNX A;  1KHQ A;  2FRA A;  4YV8 A;  2FQ9 A;  1S4V A;  3B79 A;  4PAD A;  3H8C A;  4ZUX U;  5EGW A;  2NQG A;  3QJ3 A;  5F02 A;  1F29 A;  2XU5 A;  4BPV A;  2XU3 A;  5J94 A;  4YYR A;  4K7C A;  1CVZ A;  4N79 A;  4CDE B;  3U8E A;  2AU1 A;  3PBH A;  3CH2 X;  1MDW A;  3ERV A;  3CBJ A;  3S3R A;  2P7U A;  2G8E A;  3HHA A;  4YVA A;  2E02 A;  4I07 A;  4CDD B;  2AIM A;  5JA7 A;  3S3Q A;  2OP3 A;  1X9Y A;  1CS8 A;  2YJB A;  1AU0 A;  3OVZ A;  4P6G A;  1ZCM A;  2PNS A;  1FH0 A;  3N4C A;  3DF0 A;  1AU4 A;  3M99 A;  1BQI A;  3K8U A;  2G7Y A;  1U9W A;  1CQD A;  1YK8 A;  1TLO A;  2YJ8 A;  3IEJ A;  2XU1 A;  3P5V A;  3E1Z B;  4BS5 A;  5EF4 A;  2VHF A;  4XR7 A;  2HD5 A;  2IBI A;  4DMY A;  1U9Q X;  2E01 A;  4PP2 E;  2CIO A;  4CZW A;  2HXZ A;  3V6E A;  1EWM A;  3KW9 A;  4X6H A;  2DC6 A;  3O1G A;  4QBB A;  1M6D A;  1CTE A;  4BSQ A;  2BDZ A;  3H7D A;  2Y5B A;  1GCB A;  2O6X A;  2OUL A;  3MHS A;  3OF8 A;  3C9E A;  4MZS A;  2NQD B;  1QOL A;  2XU4 A;  1U9X A;  1Y08 A;  6PAD A;  1PPP A;  1YAL A;  1PIP A;  4X6I A;  2CB5 A;  4QRV A;  2C0Y A;  2AYN A;  1MS6 A;  3KFQ A;  1CPJ A;  3WXF A;  1NL6 A;  2R9O A;  9PAP A;  4YYW A;  1GMY A;  4YYQ A;  4WA6 A;  1AIM A;  5CVM A;  2ATO A;  3H6S A;  4N4Z A;  5PAD A;  2B1M A;  4N8W A;  2HHN A;  4OEM A;  3IUT A;  3P5U A;  1PPN A;  2IPP B;  1HUC B;  5CVN B;  2PBH A;  2DJG B;  4HWY A;  2E00 A;  3USV A;  4YYS A;  1IWD A;  1GLO A;  3QSD A;  1QXP A;  3K24 A;  2GHU A;  2FRQ A;  3BCN A;  3MTN A;  3MOR A;  5K16 A;  1BGO A;  2DCA A;  2DZZ A;  4MSX A;  2YJ9 A;  1XKG A;  3GCB A;  4FIP A;  2F1G A;  3P5W A;  4BQV A;  1YT7 A;  3IOQ A;  2NQI A;  1F2C A;  1EWO A;  2YJC A;  3BPM A;  1F2B A;  2NQA A;  1K3B B;  2R9C A;  3KWZ A;  3LXS A;  1SNK A;  1EWL A;  1Q6K A;  2DJF B;  2VHS A;  5CVO B;  4DMX A;  2JQG R;  2P0R A;  2FTD A;  4RY2 A;  4X6J A;  2AS8 A;  1VJV A;  4XUI A;  3KKU A;  1EWP A;  3IMA A;  2F7D A;  1AYW A;  1PBH A;  7PCK A;  1AU2 A;  1AYV A;  2OZ2 A;  3BOW A;  3F75 A;  4PI3 A;  1CSB B;  3RVW A;  3QT4 A;  4QH6 A;  2Y6E A;  4KLB A;  4BS6 A;  2AUX A;  1KFX L;  3WXG A;  2DC8 A;  2R9N A;  1NB3 A;  1STF E;  2DCD A;  2FYE A;  2B1N A;  1ME4 A;  1BY8 A;  2E03 A;  3V6C A;  3CH3 X;  4QRX A;  3OVX A;  5JH3 A;  1GEC E;  1PPD A;  4I04 A;  3PNR A;  3K9M A;  4G54 A;  1O0E A;  4I05 A;  1DF0 A;  1YVB A;  1MEM A;  1ME3 A;  2FUD A;  1PE6 A;  1JQP A;  3KSE A;  1Y4H A;  3CBK A;  2DCB A;  1POP A;  2DCC A;  1AU3 A;  4OEL A;  1ZIV A;  1TU6 A;  1ITO A;  3I06 A;  1CJL A;  3OF9 A;  1CB5 A;  1PXV A;  5CHT A;  1ICF A;  1MIR A;  4Q8G A;  3HD3 A;  3H89 A;  1EF7 A;  3N3K A;  5CHV A;  3OIS A;  5FPW A;  1KFU L;  3NHE A;  4YYV A;  2DZY A;  1AYU A;  3KWB X;  2AVW A;  1YK7 A;  2PRE A;  3IHP A;  3H8B A;  1NQC A;  1MEG A;  2ARY A;  1CV8 A;  3WXE A;  2ACT A;  1SP4 B;  1U9V A;  3O0U A;  2DC9 A;  2H7J A;  2PAD A;  3KX1 A;  3ZUA A;  1TL9 A; 
#chains in the Genus database with same CATH topology
 3IV2 A;  4W5B A;  3RVV A;  4QRG A;  3C0R A;  1A6R A;  4RNA A;  4FJC A;  3D6S A;  2DC7 A;  2HWK A;  4AXL A;  3AI8 A;  3N3G A;  4OW0 A;  4RF1 A;  2HH5 A;  2FE8 A;  4CDF B;  1F2A A;  1AEC A;  4W5C A;  3F5V A;  2G6D A;  4FK5 A;  4CDC B;  3LFY A;  4BOZ A;  1QMY A;  1KXR A;  4YYU A;  8PCH A;  2AYO A;  2YJ2 A;  1DEU A;  3BC3 A;  1NB5 A;  2JQF R;  2P86 A;  1PAD A;  1KHP A;  2R9M A;  4BOQ A;  1NLJ A;  1PPO A;  3BWK A;  3HHI A;  4OVZ A;  2AUZ A;  4W4U A;  1NPZ A;  4BOS A;  1BP4 A;  3PW3 A;  1PCI A;  3BB7 A;  1THE A;  4MZO A;  2WBF X;  2FO5 A;  2R9F A;  2G8J A;  3ZNH A;  3I3T A;  1U5I A;  2R6N A;  2GFO A;  1VSN A;  1QDQ A;  3RVX A;  3MP2 A;  3BPF A;  4P6E A;  2BDL A;  5A24 A;  3PDF A;  4PP1 A;  3MHH A;  4AXM A;  4Q8H A;  2FT2 A;  3HWN A;  1ATK A;  3P5X A;  1MHW A;  4PT5 A;  4BOP A;  3TNX A;  1KHQ A;  2FRA A;  4YV8 A;  2BTW A;  2FQ9 A;  1S4V A;  3B79 A;  4PAD A;  3H8C A;  4ZUX U;  5EGW A;  2NQG A;  3QJ3 A;  5F02 A;  1F29 A;  2XU5 A;  4BPV A;  2XU3 A;  5J94 A;  4YYR A;  4K7C A;  1CVZ A;  4N79 A;  4XZX A;  4CDE B;  3U8E A;  2AU1 A;  4HXD B;  3PBH A;  3CH2 X;  1MDW A;  3ERV A;  3PHU A;  3CBJ A;  2J7Q C;  3S3R A;  2P7U A;  2G8E A;  3HHA A;  4YVA A;  2E02 A;  2JTC A;  4I07 A;  4CDD B;  2AIM A;  5JA7 A;  3S3Q A;  2OP3 A;  1X9Y A;  1CS8 A;  2YJB A;  1AU0 A;  3OVZ A;  4P6G A;  1ZCM A;  4IP3 A;  2PNS A;  1FH0 A;  3N4C A;  3DF0 A;  1AU4 A;  3M99 A;  1BQI A;  3K8U A;  2G7Y A;  1U9W A;  1CQD A;  1YK8 A;  1TLO A;  2YJ8 A;  3IEJ A;  2XU1 A;  3MTV A;  3P5V A;  3E1Z B;  1PVJ A;  4BS5 A;  4GUA A;  1DKI A;  5EF4 A;  2VHF A;  4XR7 A;  2HD5 A;  2IBI A;  4DMY A;  1U9Q X;  2E01 A;  4PP2 E;  2CIO A;  4CZW A;  2HXZ A;  3V6E A;  1EWM A;  3KW9 A;  4X6H A;  2DC6 A;  3O1G A;  4QBB A;  1M6D A;  1CTE A;  4BSQ A;  2BDZ A;  3H7D A;  2Y5B A;  1GCB A;  2O6X A;  2OUL A;  3MHS A;  3OF8 A;  3C9E A;  4MZS A;  3MJ5 A;  3PT2 A;  3IFU A;  2NQD B;  1QOL A;  2XU4 A;  1U9X A;  1Y08 A;  6PAD A;  1PPP A;  1YAL A;  1PIP A;  4OVZ B;  4X6I A;  2CB5 A;  3TRK A;  4QRV A;  5E6J A;  2C0Y A;  2AYN A;  1MS6 A;  3KFQ A;  1CPJ A;  3WXF A;  1NL6 A;  2R9O A;  4WUR A;  9PAP A;  4YYW A;  1GMY A;  4YYQ A;  4WA6 A;  1AIM A;  3PRM A;  5CVM A;  2ATO A;  3H6S A;  2UZJ A;  4N4Z A;  5PAD A;  2B1M A;  4N8W A;  2HHN A;  3OQC A;  4OEM A;  3IUT A;  3P5U A;  1PPN A;  2IPP B;  1HUC B;  5CVN B;  2PBH A;  2DJG B;  4HWY A;  2E00 A;  3USV A;  4YYS A;  1IWD A;  1GLO A;  3QSD A;  1QXP A;  3K24 A;  2GHU A;  4MI7 A;  2FRQ A;  3BCN A;  3MTN A;  3MOR A;  5K16 A;  3PRP A;  1BGO A;  2DCA A;  2DZZ A;  2JRI A;  4MSX A;  5KO3 A;  2YJ9 A;  1XKG A;  3W30 A;  3GCB A;  4FIP A;  2F1G A;  3P5W A;  4BQV A;  1YT7 A;  3IOQ A;  2NQI A;  1F2C A;  1EWO A;  2YJC A;  3BPM A;  1F2B A;  4RKX A;  5JZE A;  2NQA A;  3O65 A;  1K3B B;  2R9C A;  3KWZ A;  3LXS A;  1SNK A;  4R3D A;  1EWL A;  1Q6K A;  4IUM A;  2DJF B;  2VHS A;  5CVO B;  4DMX A;  2JQG R;  2P0R A;  2FTD A;  4RY2 A;  2AGA A;  4X6J A;  3PHW A;  2AS8 A;  1VJV A;  5EZQ A;  4XUI A;  3KKU A;  1EWP A;  3IMA A;  3B21 A;  2F7D A;  3W31 A;  1AYW A;  1PBH A;  7PCK A;  1AU2 A;  1AYV A;  2OZ2 A;  3BOW A;  3F75 A;  4PI3 A;  5EZS A;  1CSB B;  3RVW A;  3QT4 A;  4QH6 A;  2Y6E A;  4KLB A;  4BS6 A;  2AUX A;  1KFX L;  3WXG A;  2DC8 A;  2R9N A;  4A5U A;  4REZ A;  1NB3 A;  1STF E;  1YZB A;  2DCD A;  2FYE A;  2B1N A;  1ME4 A;  1BY8 A;  2E03 A;  3V6C A;  3CH3 X;  4QRX A;  3OVX A;  5JH3 A;  4D8I A;  3PSE A;  1GEC E;  1PPD A;  4I04 A;  4MM3 B;  3PHX A;  3PNR A;  3K9M A;  3RNV A;  4G54 A;  1O0E A;  2Z84 A;  4I05 A;  1DF0 A;  1YVB A;  1MEM A;  1ME3 A;  2FUD A;  2DOS A;  4RF0 A;  1PE6 A;  3TMP A;  1JQP A;  3KSE A;  1Y4H A;  3CBK A;  2DCB A;  1POP A;  4P16 A;  2DCC A;  1AU3 A;  4OEL A;  1ZIV A;  1TU6 A;  2BTW B;  1ITO A;  3BY4 A;  3I06 A;  3E9S A;  1CJL A;  2BU3 A;  3OF9 A;  1CB5 A;  1PXV A;  3BBA A;  5CHT A;  1ICF A;  4D8E A;  1MIR A;  4BOU A;  4Q8G A;  1UKF A;  3HD3 A;  3H89 A;  2J7Q A;  1EF7 A;  3N3K A;  4D8B A;  5CHV A;  3OIS A;  5FPW A;  4M0W A;  1KFU L;  3NHE A;  4YYV A;  2DZY A;  1AYU A;  3KWB X;  2AVW A;  1YK7 A;  2PRE A;  3IHP A;  3H8B A;  1NQC A;  4ZTB A;  1MEG A;  2ARY A;  1CV8 A;  3WXE A;  2ACT A;  1SP4 B;  1U9V A;  3O0U A;  2DC9 A;  2H7J A;  2PAD A;  3KX1 A;  3ZUA A;  1TL9 A; 
#chains in the Genus database with same CATH homology
 3IV2 A;  4W5B A;  3RVV A;  4QRG A;  1A6R A;  4FJC A;  3D6S A;  2DC7 A;  4AXL A;  3AI8 A;  3N3G A;  2HH5 A;  4CDF B;  1F2A A;  1AEC A;  4W5C A;  3F5V A;  2G6D A;  4FK5 A;  4CDC B;  3LFY A;  1QMY A;  1KXR A;  4YYU A;  8PCH A;  2AYO A;  2YJ2 A;  1DEU A;  3BC3 A;  1NB5 A;  2JQF R;  2P86 A;  1PAD A;  1KHP A;  2R9M A;  1GX3 A;  1NLJ A;  1PPO A;  3BWK A;  3HHI A;  2BSZ A;  2AUZ A;  2VFC A;  4W4U A;  1NPZ A;  1BP4 A;  3PW3 A;  1PCI A;  1THE A;  4MZO A;  2WBF X;  2FO5 A;  2R9F A;  2G8J A;  3I3T A;  1U5I A;  2R6N A;  2GFO A;  1VSN A;  1QDQ A;  3RVX A;  3BPF A;  4P6E A;  2BDL A;  5A24 A;  3PDF A;  4PP1 A;  3MHH A;  4AXM A;  4Q8H A;  2FT2 A;  3HWN A;  2VFB A;  1ATK A;  3P5X A;  1MHW A;  3TNX A;  1KHQ A;  2FRA A;  4YV8 A;  2FQ9 A;  1W5R A;  1S4V A;  3B79 A;  4PAD A;  3H8C A;  4ZUX U;  5EGW A;  2NQG A;  3QJ3 A;  5F02 A;  1F29 A;  2XU5 A;  4BPV A;  2XU3 A;  5J94 A;  4YYR A;  4K7C A;  1CVZ A;  4N79 A;  4CDE B;  3U8E A;  2AU1 A;  3PBH A;  3CH2 X;  1MDW A;  3ERV A;  3CBJ A;  3S3R A;  2P7U A;  2G8E A;  3HHA A;  4YVA A;  2E02 A;  1W4T A;  4I07 A;  4CDD B;  2AIM A;  5JA7 A;  3S3Q A;  3D9W A;  2OP3 A;  1X9Y A;  1CS8 A;  2YJB A;  1AU0 A;  3OVZ A;  4P6G A;  1ZCM A;  2PNS A;  1FH0 A;  3N4C A;  3DF0 A;  1AU4 A;  3M99 A;  1BQI A;  3K8U A;  2G7Y A;  1U9W A;  4B55 A;  1CQD A;  1YK8 A;  1TLO A;  2YJ8 A;  3IEJ A;  2XU1 A;  3P5V A;  3E1Z B;  4BS5 A;  5EF4 A;  2VHF A;  4XR7 A;  2HD5 A;  2IBI A;  4DMY A;  1U9Q X;  1W6F A;  2E01 A;  4PP2 E;  2CIO A;  4CZW A;  2HXZ A;  3V6E A;  1EWM A;  3KW9 A;  4X6H A;  2DC6 A;  3O1G A;  4QBB A;  1M6D A;  1CTE A;  4BSQ A;  2BDZ A;  3H7D A;  2Y5B A;  1GCB A;  2O6X A;  2OUL A;  3MHS A;  3OF8 A;  3C9E A;  4MZS A;  2NQD B;  1QOL A;  2XU4 A;  1U9X A;  1Y08 A;  6PAD A;  1PPP A;  1YAL A;  1PIP A;  4X6I A;  2CB5 A;  4QRV A;  1E2T A;  2C0Y A;  2AYN A;  1MS6 A;  3KFQ A;  1CPJ A;  3WXF A;  1NL6 A;  2R9O A;  9PAP A;  4C5P A;  4YYW A;  1GMY A;  4YYQ A;  4WA6 A;  1AIM A;  5CVM A;  2ATO A;  3H6S A;  4N4Z A;  5PAD A;  2B1M A;  4N8W A;  2HHN A;  4OEM A;  3IUT A;  3P5U A;  1PPN A;  2IPP B;  1HUC B;  5CVN B;  2PBH A;  2DJG B;  4HWY A;  2E00 A;  3USV A;  4YYS A;  1IWD A;  1GLO A;  3QSD A;  1QXP A;  3K24 A;  2GHU A;  2FRQ A;  3BCN A;  3MTN A;  3MOR A;  5K16 A;  1BGO A;  2DCA A;  2DZZ A;  4MSX A;  2YJ9 A;  1XKG A;  3GCB A;  4FIP A;  2F1G A;  3P5W A;  4BQV A;  1YT7 A;  3IOQ A;  2NQI A;  1F2C A;  1EWO A;  2YJC A;  3BPM A;  1F2B A;  2NQA A;  4BGF A;  1K3B B;  2R9C A;  3KWZ A;  3LXS A;  1SNK A;  1EWL A;  1Q6K A;  2DJF B;  2VHS A;  5CVO B;  4DMX A;  2JQG R;  2P0R A;  2FTD A;  4RY2 A;  4X6J A;  2AS8 A;  1VJV A;  4XUI A;  3KKU A;  1EWP A;  3IMA A;  2F7D A;  1AYW A;  1PBH A;  7PCK A;  1AU2 A;  1AYV A;  2OZ2 A;  3BOW A;  3F75 A;  4PI3 A;  1CSB B;  3RVW A;  3QT4 A;  4QH6 A;  4GUZ A;  2Y6E A;  4KLB A;  4BS6 A;  2AUX A;  1KFX L;  4NV7 A;  3WXG A;  2DC8 A;  2R9N A;  1NB3 A;  1STF E;  2DCD A;  2FYE A;  2B1N A;  3LTW A;  1ME4 A;  1BY8 A;  2E03 A;  3V6C A;  3CH3 X;  4QRX A;  3OVX A;  5JH3 A;  1GEC E;  1PPD A;  4I04 A;  3PNR A;  3K9M A;  4G54 A;  1O0E A;  4I05 A;  1DF0 A;  1YVB A;  1MEM A;  4NV8 A;  1ME3 A;  2FUD A;  1PE6 A;  1JQP A;  3KSE A;  1Y4H A;  3CBK A;  2DCB A;  1POP A;  2DCC A;  1AU3 A;  4OEL A;  1ZIV A;  1TU6 A;  1ITO A;  3I06 A;  1CJL A;  3OF9 A;  1CB5 A;  1PXV A;  5CHT A;  1ICF A;  1MIR A;  4Q8G A;  3HD3 A;  3H89 A;  1EF7 A;  3N3K A;  5CHV A;  3OIS A;  5FPW A;  1KFU L;  3NHE A;  4YYV A;  2DZY A;  1AYU A;  3KWB X;  2AVW A;  1YK7 A;  2PRE A;  3IHP A;  3H8B A;  1NQC A;  1MEG A;  2ARY A;  1CV8 A;  3WXE A;  2ACT A;  1SP4 B;  1U9V A;  3O0U A;  2DC9 A;  2H7J A;  2PAD A;  3KX1 A;  3ZUA A;  1TL9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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