4HWYA

Trypanosoma brucei procathepsin b solved from 40 fs free-electron laser pulse data by serial femtosecond x-ray crystallography
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
314
structure length
308
Chain Sequence
EDAPVLSKAFVDRVNRLNRGIWKAKYDGVMQNITLREAKRLNGVIKILPKRRFTEEEARAPLPSSFDSAEAWPNCPTIPQIADQSACGSCWAVAAASAMSDRFCTMGGVQDVHISAGDLLACCSDCGDGCNGGDPDRAWAYFSSTGLVSDYCQPYPFPHCSHHSKSKNGYPPCSQFNFDTPKCNYTCDDPTIPVVNYRSWTSYALQGEDDYMRELFFRGPFEVAFDVYEDFIAYNSGVYHHVSGQYLGGHAVRLVGWGTSNGVPYWKIANSWNTEWGMDGYFLIRRGSSECGIEDGGSAGIPLAPNTA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Cysteine peptidase C (CPC)
publication title Natively inhibited Trypanosoma brucei cathepsin B structure determined by using an X-ray laser.
pubmed doi rcsb
source organism Trypanosoma brucei brucei treu927
molecule tags Hydrolase
total genus 98
structure length 308
sequence length 314
ec nomenclature ec 3.4.22.-:
pdb deposition date 2012-11-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 4hwyA00
1EWLA 3GCBA 1BY8A 2E00A 1U9WA 2R9NA 4OEMA 2XU4A 1AYWA 4CDFB 2NQGA 1VJVA 4DMYA 3IOQA 1CV8A 1TU6A 3QJ3A 1NB5A 3HHAA 3KKUA 1NPZA 3KWZA 1NB3A 3H89A 1MEGA 3V6CA 1U9XA 2XU5A 1M6DA 3TNXA 4OELA 3D6SA 4BSQA 2Y6EA 8PCHA 1QDQA 3BPFA 2DCCA 5JA7A 2JQGR 1Q6KA 2DCDA 5FPWA 3WXFA 2YJCA 3P5WA 4BPVA 3N3GA 3IV2A 2PREA 2B1MA 4AXMA 3PNRA 3HHIA 2E02A 2FRQA 1PBHA 4FIPA 3O1GA 4W5CA 2G7YA 2IPPB 3CBKA 4N4ZA 2FRAA 5F02A 7PCKA 1CSBB 4X6JA 2DZYA 1MEMA 1PPPA 2BDLA 1MHWA 1POPA 2YJ8A 3H8BA 4YV8A 2AUXA 3P5XA 3USVA 2WBFX 1F2AA 3QSDA 1AU0A 3MHHA 3ZUAA 3OF9A 1DF0A 4FK5A 2IBIA 5J94A 1ITOA 5PADA 3NHEA 2R9OA 4MSXA 4YYVA 2AS8A 1O0EA 2CB5A 2FUDA 3B79A 5EGWA 1CS8A 1YVBA 3DF0A 1NLJA 1KXRA 1GLOA 2GHUA 4ZUXU 4PP2E 4WA6A 1MDWA 4XUIA 1STFE 1NQCA 4G54A 4X6IA 3C9EA 4BS5A 4YYQA 1S4VA 3IEJA 2NQAA 2NQDB 2E03A 2FT2A 3AI8A 4N79A 4QRVA 2YJBA 4W5BA 2DCAA 1CPJA 3MHSA 4AXLA 3S3QA 1SNKA 1AU4A 2PBHA 3OISA 2AYNA 3BPMA 1AYVA 3IUTA 3N4CA 1YALA 1AU3A 1CTEA 1NL6A 3PBHA 3RVVA 1HUCB 1PADA 1PPDA 4QH6A 2AUZA 1IWDA 1KHQA 3BC3A 4KLBA 3P5VA 2O6XA 2DZZA 2HHNA 2CIOA 1QOLA 2GFOA 3KSEA 2FTDA 3CH2X 2FQ9A 2DC9A 1PIPA 4RY2A 5EF4A 1CB5A 3P5UA 1DEUA 5JH3A 1BQIA 2R9CA 3V6EA 1AU2A 2NQIA 1U5IA 2FYEA 4N8WA 3S3RA 3H7DA 3OVZA 2B1NA 2ATOA 3F75A 5CHVA 4I05A 1SP4B 1THEA 3BOWA 4YYUA 1YK8A 2G6DA 1PE6A 1QXPA 3CH3X 4K7CA 1EWPA 2AVWA 2AU1A 2OP3A 1Y4HA 2HD5A 1ME4A 2OZ2A 4Q8GA 2P0RA 1ATKA 4QRXA 1BP4A 1U9VA 2H7JA 3E1ZB 2C0YA 4I04A 4QBBA 1KFXL 2E01A 2VHSA 4CDDB 2F1GA 3IMAA 5CVOB 3WXGA 1PXVA 1EF7A 2HH5A 3N3KA 1KHPA 3MTNA 1TL9A 3RVXA 4Q8HA 4BQVA 4YYSA 1F2CA 2P86A 3PW3A 3KFQA 3OF8A 4CZWA 2YJ9A 2FO5A 2DJFB 3KW9A 4YYWA 4YVAA 3MORA 3BWKA 3H6SA 1ME3A 2DC6A 1ZCMA 2PNSA 4HWYA 1ZIVA 4PI3A 3K9MA 1K3BB 2PADA 2JQFR 3QT4A 1GMYA 3O0UA 1AIMA 4DMXA 1F29A 3OVXA 2DCBA 1CJLA 1X9YA 1GECE 3HD3A 6PADA 1CVZA 4W4UA 1EWMA 2HXZA 2YJ2A 3I3TA 2BDZA 1YK7A 2R6NA 2Y5BA 4MZOA 5A24A 1PCIA 2AYOA 2XU1A 1PPNA 4CDEB 1MIRA 1AECA 2ARYA 3K8UA 3M99A 3CBJA 2G8JA 5K16A 1KFUL 3LFYA 1AYUA 4YYRA 5CVMA 3BCNA 3RVWA 1MS6A 1TLOA 1EWOA 3KX1A 2AIMA 5CVNB 1YT7A 3PDFA 4P6EA 3LXSA 2DC7A 4CDCB 3WXEA 1A6RA 2DJGB 2G8EA 2DC8A 4I07A 1JQPA 2OULA 1PPOA 3F5VA 3K24A 1Y08A 2R9FA 2P7UA 3U8EA 4QRGA 4P6GA 9PAPA 1QMYA 3ERVA 1ICFA 1FH0A 4FJCA 2XU3A 2F7DA 4PP1A 1U9QX 1CQDA 2ACTA 3I06A 1GCBA 1BGOA 1XKGA 3KWBX 2R9MA 3H8CA 1F2BA 4X6HA 4BS6A 3IHPA 4XR7A 5CHTA 1VSNA 4PADA 2VHFA 3HWNA 4MZSA
chains in the Genus database with same CATH superfamily
1EWLA 4BOPA 3GCBA 1BY8A 4IP3A 2E00A 4D8EA 1U9WA 2R9NA 4OEMA 2XU4A 4MM3B 1AYWA 4CDFB 2NQGA 1VJVA 4DMYA 3IOQA 4M0WA 1CV8A 1TU6A 3QJ3A 1NB5A 3HHAA 3KKUA 1NPZA 4REZA 3KWZA 1NB3A 3H89A 1MEGA 3V6CA 1U9XA 5KO3A 2XU5A 1M6DA 1UKFA 3TNXA 4OELA 3D6SA 4OVZA 4BSQA 2Y6EA 8PCHA 4P16A 1QDQA 3BPFA 2DCCA 5JA7A 3PHUA 2JQGR 1Q6KA 2DCDA 5FPWA 3WXFA 4A5UA 2YJCA 1YZBA 3P5WA 4BPVA 3N3GA 3IV2A 2PREA 2B1MA 4AXMA 3PNRA 4GUAA 4RF0A 3HHIA 2E02A 5EZQA 2FRQA 1PVJA 1PBHA 4FIPA 4XZXA 3O1GA 4W5CA 2G7YA 2IPPB 4BOSA 3CBKA 4N4ZA 2FRAA 5F02A 2AGAA 7PCKA 1CSBB 2BTWA 4X6JA 2DZYA 1MEMA 1PPPA 2BDLA 1MHWA 1POPA 2YJ8A 3H8BA 4YV8A 2AUXA 3P5XA 3USVA 2WBFX 1F2AA 3QSDA 1AU0A 3MHHA 3ZUAA 3OF9A 1DF0A 3RNVA 4FK5A 2IBIA 5J94A 1ITOA 5PADA 3NHEA 2R9OA 4MSXA 4YYVA 2AS8A 1O0EA 2CB5A 2FUDA 5EZSA 3B79A 5EGWA 3MTVA 3PRMA 1CS8A 1YVBA 3DF0A 1NLJA 1KXRA 1GLOA 2GHUA 4ZUXU 4PP2E 4WA6A 1MDWA 4XUIA 1STFE 1NQCA 4G54A 4X6IA 3C9EA 4BS5A 4YYQA 2DOSA 1S4VA 3IEJA 2NQAA 4RF1A 2NQDB 2E03A 2FT2A 3AI8A 4IUMA 4N79A 4QRVA 2YJBA 4W5BA 2DCAA 1CPJA 3MHSA 4AXLA 3S3QA 3TRKA 1SNKA 1AU4A 2PBHA 3OISA 2AYNA 3BPMA 1AYVA 3IUTA 3N4CA 1YALA 1AU3A 1CTEA 1NL6A 3B21A 3PBHA 3RVVA 1HUCB 1PADA 1PPDA 4QH6A 2AUZA 1IWDA 2BTWB 1KHQA 3BC3A 3IFUA 2JRIA 4KLBA 3P5VA 2O6XA 2DZZA 2HHNA 2CIOA 1QOLA 2GFOA 4BOZA 3KSEA 2FTDA 3CH2X 2FQ9A 2DC9A 1PIPA 4RY2A 5EF4A 1CB5A 3P5UA 1DEUA 5JH3A 1BQIA 2R9CA 3V6EA 3TMPA 1AU2A 3ZNHA 2NQIA 1U5IA 3MP2A 2FYEA 4N8WA 3C0RA 3S3RA 3H7DA 3BY4A 4BOUA 3OVZA 4ZTBA 2B1NA 2ATOA 3F75A 5CHVA 4I05A 1SP4B 3W31A 3PRPA 1THEA 3BOWA 4YYUA 1YK8A 2G6DA 4D8BA 1PE6A 1QXPA 3CH3X 4K7CA 1EWPA 2AVWA 2AU1A 2OP3A 1Y4HA 2HD5A 1ME4A 2OZ2A 4Q8GA 2P0RA 1ATKA 4QRXA 1BP4A 1U9VA 2H7JA 3E1ZB 2C0YA 1DKIA 4I04A 4QBBA 5E6JA 1KFXL 2E01A 4R3DA 2VHSA 4OVZB 4CDDB 2F1GA 3IMAA 5CVOB 3WXGA 1PXVA 1EF7A 2HH5A 3N3KA 2J7QC 1KHPA 3MTNA 2BU3A 1TL9A 3RVXA 4Q8HA 4BQVA 4YYSA 3W30A 1F2CA 2P86A 3PW3A 3KFQA 3OF8A 4CZWA 2YJ9A 2FO5A 2DJFB 3KW9A 4YYWA 4YVAA 3PHXA 3MORA 3BWKA 2JTCA 3BB7A 3H6SA 1ME3A 2DC6A 1ZCMA 2PNSA 4HWYA 1ZIVA 4PI3A 2Z84A 3K9MA 1K3BB 2PADA 2JQFR 3QT4A 1GMYA 3O0UA 1AIMA 4DMXA 1F29A 3OVXA 4WURA 2DCBA 1CJLA 1X9YA 4RKXA 5JZEA 1GECE 4MI7A 3HD3A 6PADA 1CVZA 4W4UA 1EWMA 2HXZA 4PT5A 2YJ2A 2J7QA 3I3TA 2BDZA 1YK7A 2R6NA 2Y5BA 3OQCA 4MZOA 4HXDB 5A24A 1PCIA 4OW0A 2AYOA 4D8IA 2XU1A 1PPNA 4CDEB 1MIRA 3PSEA 1AECA 2ARYA 3K8UA 3M99A 3CBJA 2G8JA 5K16A 1KFUL 3LFYA 1AYUA 4YYRA 3MJ5A 5CVMA 3BCNA 3BBAA 3RVWA 1MS6A 1TLOA 1EWOA 3KX1A 2AIMA 5CVNB 1YT7A 3PDFA 4MZSA 2HWKA 3O65A 4P6EA 3LXSA 2DC7A 4CDCB 3WXEA 1A6RA 2DJGB 2FE8A 2G8EA 2DC8A 4I07A 1JQPA 2OULA 1PPOA 3F5VA 3K24A 1Y08A 2R9FA 2P7UA 3U8EA 4QRGA 4P6GA 9PAPA 1QMYA 3ERVA 1ICFA 1FH0A 2UZJA 4FJCA 3PHWA 2XU3A 2F7DA 4PP1A 1U9QX 1CQDA 2ACTA 3I06A 1GCBA 1BGOA 1XKGA 3KWBX 2R9MA 4BOQA 3H8CA 1F2BA 4X6HA 4BS6A 3IHPA 4XR7A 5CHTA 1VSNA 4PADA 2VHFA 3E9SA 4RNAA 3HWNA 3PT2A
chains in the Genus database with same CATH topology
1EWLA 3GCBA 1BY8A 2E00A 1U9WA 2R9NA 4OEMA 2XU4A 1AYWA 4CDFB 2NQGA 1VJVA 4DMYA 3IOQA 1CV8A 1TU6A 3QJ3A 1NB5A 3HHAA 3KKUA 1W4TA 1NPZA 3KWZA 1NB3A 3H89A 1MEGA 3V6CA 1U9XA 2XU5A 1M6DA 3TNXA 4OELA 3D6SA 4BSQA 2Y6EA 8PCHA 1QDQA 3BPFA 2DCCA 5JA7A 2JQGR 1Q6KA 2DCDA 5FPWA 3WXFA 2YJCA 3P5WA 4BPVA 3N3GA 3IV2A 2PREA 2B1MA 4AXMA 3PNRA 4NV7A 3HHIA 2E02A 2FRQA 1PBHA 4FIPA 3O1GA 4W5CA 2G7YA 2IPPB 3CBKA 4N4ZA 2FRAA 5F02A 2VFBA 7PCKA 1CSBB 4C5PA 4X6JA 2DZYA 1MEMA 1PPPA 2BDLA 1MHWA 1POPA 2YJ8A 3H8BA 4YV8A 2AUXA 3P5XA 3USVA 2WBFX 1F2AA 3QSDA 1AU0A 3MHHA 3ZUAA 3OF9A 1DF0A 4FK5A 2IBIA 5J94A 1ITOA 5PADA 3NHEA 2R9OA 4MSXA 4YYVA 2AS8A 1O0EA 2CB5A 2FUDA 4BGFA 3LTWA 3B79A 5EGWA 1CS8A 1YVBA 3DF0A 1NLJA 1KXRA 1GLOA 2GHUA 4ZUXU 4PP2E 4WA6A 1MDWA 4XUIA 1STFE 1NQCA 4G54A 4X6IA 3C9EA 1E2TA 4BS5A 4YYQA 1S4VA 3IEJA 2NQAA 2NQDB 2E03A 2FT2A 3AI8A 4N79A 4QRVA 4NV8A 2YJBA 4W5BA 2DCAA 1CPJA 1GX3A 3MHSA 4AXLA 3S3QA 1SNKA 3D9WA 1AU4A 2PBHA 3OISA 2AYNA 3BPMA 1AYVA 3IUTA 3N4CA 1YALA 1AU3A 1CTEA 1NL6A 3PBHA 3RVVA 1HUCB 1PADA 1PPDA 4QH6A 2AUZA 1IWDA 1KHQA 3BC3A 4KLBA 3P5VA 2O6XA 2DZZA 2HHNA 2CIOA 1QOLA 2GFOA 3KSEA 2FTDA 3CH2X 2FQ9A 2DC9A 1PIPA 4RY2A 5EF4A 1CB5A 3P5UA 1DEUA 5JH3A 1BQIA 2R9CA 3V6EA 1AU2A 2NQIA 1U5IA 2FYEA 4N8WA 3S3RA 3H7DA 3OVZA 2B1NA 2ATOA 3F75A 5CHVA 4I05A 1SP4B 1THEA 3BOWA 4YYUA 1YK8A 2G6DA 1PE6A 4K7CA 1QXPA 3CH3X 1EWPA 2AVWA 2AU1A 2OP3A 1Y4HA 2HD5A 1ME4A 2OZ2A 4Q8GA 2P0RA 1ATKA 4QRXA 1BP4A 1U9VA 2H7JA 3E1ZB 2C0YA 4I04A 4QBBA 1KFXL 2E01A 2VHSA 4CDDB 2F1GA 3IMAA 5CVOB 3WXGA 1PXVA 1EF7A 2HH5A 3N3KA 1KHPA 3MTNA 1TL9A 3RVXA 4Q8HA 4BQVA 4YYSA 1F2CA 2P86A 3PW3A 3KFQA 3OF8A 4CZWA 2YJ9A 2FO5A 2DJFB 3KW9A 4YYWA 4YVAA 3MORA 3BWKA 2VFCA 3H6SA 1ME3A 2DC6A 1ZCMA 2PNSA 4HWYA 1ZIVA 4PI3A 3K9MA 1K3BB 2PADA 2JQFR 3QT4A 1GMYA 3O0UA 1AIMA 4DMXA 1F29A 3OVXA 2DCBA 1CJLA 4B55A 4GUZA 1X9YA 1GECE 3HD3A 6PADA 1CVZA 4W4UA 1EWMA 2HXZA 2YJ2A 3I3TA 2BDZA 1YK7A 2R6NA 2Y5BA 4MZOA 5A24A 1PCIA 2AYOA 2XU1A 1PPNA 2BSZA 4CDEB 1MIRA 1AECA 2ARYA 3K8UA 3M99A 3CBJA 2G8JA 5K16A 1KFUL 3LFYA 1AYUA 4YYRA 1W5RA 5CVMA 1W6FA 3BCNA 3RVWA 1MS6A 1TLOA 1EWOA 3KX1A 2AIMA 5CVNB 1YT7A 3PDFA 4P6EA 3LXSA 2DC7A 4CDCB 3WXEA 1A6RA 2DJGB 2G8EA 2DC8A 4I07A 1JQPA 2OULA 1PPOA 3F5VA 3K24A 1Y08A 2R9FA 2P7UA 3U8EA 4QRGA 4P6GA 9PAPA 1QMYA 3ERVA 1ICFA 1FH0A 4FJCA 2XU3A 2F7DA 4PP1A 1U9QX 1CQDA 2ACTA 3I06A 1GCBA 1BGOA 1XKGA 3KWBX 2R9MA 3H8CA 1F2BA 4X6HA 4BS6A 3IHPA 4XR7A 5CHTA 1VSNA 4PADA 2VHFA 3HWNA 4MZSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EWL A;  3GCB A;  1BY8 A;  2E00 A;  1U9W A;  2R9N A;  4OEM A;  2XU4 A;  1AYW A;  4CDF B;  2NQG A;  1VJV A;  4DMY A;  3IOQ A;  1CV8 A;  1TU6 A;  3QJ3 A;  1NB5 A;  3HHA A;  3KKU A;  1NPZ A;  3KWZ A;  1NB3 A;  3H89 A;  1MEG A;  3V6C A;  1U9X A;  2XU5 A;  1M6D A;  3TNX A;  4OEL A;  3D6S A;  4BSQ A;  2Y6E A;  8PCH A;  1QDQ A;  3BPF A;  2DCC A;  5JA7 A;  2JQG R;  1Q6K A;  2DCD A;  5FPW A;  3WXF A;  2YJC A;  3P5W A;  4BPV A;  3N3G A;  3IV2 A;  2PRE A;  2B1M A;  4AXM A;  3PNR A;  3HHI A;  2E02 A;  2FRQ A;  1PBH A;  4FIP A;  3O1G A;  4W5C A;  2G7Y A;  2IPP B;  3CBK A;  4N4Z A;  2FRA A;  5F02 A;  7PCK A;  1CSB B;  4X6J A;  2DZY A;  1MEM A;  1PPP A;  2BDL A;  1MHW A;  1POP A;  2YJ8 A;  3H8B A;  4YV8 A;  2AUX A;  3P5X A;  3USV A;  2WBF X;  1F2A A;  3QSD A;  1AU0 A;  3MHH A;  3ZUA A;  3OF9 A;  1DF0 A;  4FK5 A;  2IBI A;  5J94 A;  1ITO A;  5PAD A;  3NHE A;  2R9O A;  4MSX A;  4YYV A;  2AS8 A;  1O0E A;  2CB5 A;  2FUD A;  3B79 A;  5EGW A;  1CS8 A;  1YVB A;  3DF0 A;  1NLJ A;  1KXR A;  1GLO A;  2GHU A;  4ZUX U;  4PP2 E;  4WA6 A;  1MDW A;  4XUI A;  1STF E;  1NQC A;  4G54 A;  4X6I A;  3C9E A;  4BS5 A;  4YYQ A;  1S4V A;  3IEJ A;  2NQA A;  2NQD B;  2E03 A;  2FT2 A;  3AI8 A;  4N79 A;  4QRV A;  2YJB A;  4W5B A;  2DCA A;  1CPJ A;  3MHS A;  4AXL A;  3S3Q A;  1SNK A;  1AU4 A;  2PBH A;  3OIS A;  2AYN A;  3BPM A;  1AYV A;  3IUT A;  3N4C A;  1YAL A;  1AU3 A;  1CTE A;  1NL6 A;  3PBH A;  3RVV A;  1HUC B;  1PAD A;  1PPD A;  4QH6 A;  2AUZ A;  1IWD A;  1KHQ A;  3BC3 A;  4KLB A;  3P5V A;  2O6X A;  2DZZ A;  2HHN A;  2CIO A;  1QOL A;  2GFO A;  3KSE A;  2FTD A;  3CH2 X;  2FQ9 A;  2DC9 A;  1PIP A;  4RY2 A;  5EF4 A;  1CB5 A;  3P5U A;  1DEU A;  5JH3 A;  1BQI A;  2R9C A;  3V6E A;  1AU2 A;  2NQI A;  1U5I A;  2FYE A;  4N8W A;  3S3R A;  3H7D A;  3OVZ A;  2B1N A;  2ATO A;  3F75 A;  5CHV A;  4I05 A;  1SP4 B;  1THE A;  3BOW A;  4YYU A;  1YK8 A;  2G6D A;  1PE6 A;  1QXP A;  3CH3 X;  4K7C A;  1EWP A;  2AVW A;  2AU1 A;  2OP3 A;  1Y4H A;  2HD5 A;  1ME4 A;  2OZ2 A;  4Q8G A;  2P0R A;  1ATK A;  4QRX A;  1BP4 A;  1U9V A;  2H7J A;  3E1Z B;  2C0Y A;  4I04 A;  4QBB A;  1KFX L;  2E01 A;  2VHS A;  4CDD B;  2F1G A;  3IMA A;  5CVO B;  3WXG A;  1PXV A;  1EF7 A;  2HH5 A;  3N3K A;  1KHP A;  3MTN A;  1TL9 A;  3RVX A;  4Q8H A;  4BQV A;  4YYS A;  1F2C A;  2P86 A;  3PW3 A;  3KFQ A;  3OF8 A;  4CZW A;  2YJ9 A;  2FO5 A;  2DJF B;  3KW9 A;  4YYW A;  4YVA A;  3MOR A;  3BWK A;  3H6S A;  1ME3 A;  2DC6 A;  1ZCM A;  2PNS A;  4HWY A;  1ZIV A;  4PI3 A;  3K9M A;  1K3B B;  2PAD A;  2JQF R;  3QT4 A;  1GMY A;  3O0U A;  1AIM A;  4DMX A;  1F29 A;  3OVX A;  2DCB A;  1CJL A;  1X9Y A;  1GEC E;  3HD3 A;  6PAD A;  1CVZ A;  4W4U A;  1EWM A;  2HXZ A;  2YJ2 A;  3I3T A;  2BDZ A;  1YK7 A;  2R6N A;  2Y5B A;  4MZO A;  5A24 A;  1PCI A;  2AYO A;  2XU1 A;  1PPN A;  4CDE B;  1MIR A;  1AEC A;  2ARY A;  3K8U A;  3M99 A;  3CBJ A;  2G8J A;  5K16 A;  1KFU L;  3LFY A;  1AYU A;  4YYR A;  5CVM A;  3BCN A;  3RVW A;  1MS6 A;  1TLO A;  1EWO A;  3KX1 A;  2AIM A;  5CVN B;  1YT7 A;  3PDF A;  4P6E A;  3LXS A;  2DC7 A;  4CDC B;  3WXE A;  1A6R A;  2DJG B;  2G8E A;  2DC8 A;  4I07 A;  1JQP A;  2OUL A;  1PPO A;  3F5V A;  3K24 A;  1Y08 A;  2R9F A;  2P7U A;  3U8E A;  4QRG A;  4P6G A;  9PAP A;  1QMY A;  3ERV A;  1ICF A;  1FH0 A;  4FJC A;  2XU3 A;  2F7D A;  4PP1 A;  1U9Q X;  1CQD A;  2ACT A;  3I06 A;  1GCB A;  1BGO A;  1XKG A;  3KWB X;  2R9M A;  3H8C A;  1F2B A;  4X6H A;  4BS6 A;  3IHP A;  4XR7 A;  5CHT A;  1VSN A;  4PAD A;  2VHF A;  3HWN A;  4MZS A; 
#chains in the Genus database with same CATH topology
 1EWL A;  4BOP A;  3GCB A;  1BY8 A;  4IP3 A;  2E00 A;  4D8E A;  1U9W A;  2R9N A;  4OEM A;  2XU4 A;  4MM3 B;  1AYW A;  4CDF B;  2NQG A;  1VJV A;  4DMY A;  3IOQ A;  4M0W A;  1CV8 A;  1TU6 A;  3QJ3 A;  1NB5 A;  3HHA A;  3KKU A;  1NPZ A;  4REZ A;  3KWZ A;  1NB3 A;  3H89 A;  1MEG A;  3V6C A;  1U9X A;  5KO3 A;  2XU5 A;  1M6D A;  1UKF A;  3TNX A;  4OEL A;  3D6S A;  4OVZ A;  4BSQ A;  2Y6E A;  8PCH A;  4P16 A;  1QDQ A;  3BPF A;  2DCC A;  5JA7 A;  3PHU A;  2JQG R;  1Q6K A;  2DCD A;  5FPW A;  3WXF A;  4A5U A;  2YJC A;  1YZB A;  3P5W A;  4BPV A;  3N3G A;  3IV2 A;  2PRE A;  2B1M A;  4AXM A;  3PNR A;  4GUA A;  4RF0 A;  3HHI A;  2E02 A;  5EZQ A;  2FRQ A;  1PVJ A;  1PBH A;  4FIP A;  4XZX A;  3O1G A;  4W5C A;  2G7Y A;  2IPP B;  4BOS A;  3CBK A;  4N4Z A;  2FRA A;  5F02 A;  2AGA A;  7PCK A;  1CSB B;  2BTW A;  4X6J A;  2DZY A;  1MEM A;  1PPP A;  2BDL A;  1MHW A;  1POP A;  2YJ8 A;  3H8B A;  4YV8 A;  2AUX A;  3P5X A;  3USV A;  2WBF X;  1F2A A;  3QSD A;  1AU0 A;  3MHH A;  3ZUA A;  3OF9 A;  1DF0 A;  3RNV A;  4FK5 A;  2IBI A;  5J94 A;  1ITO A;  5PAD A;  3NHE A;  2R9O A;  4MSX A;  4YYV A;  2AS8 A;  1O0E A;  2CB5 A;  2FUD A;  5EZS A;  3B79 A;  5EGW A;  3MTV A;  3PRM A;  1CS8 A;  1YVB A;  3DF0 A;  1NLJ A;  1KXR A;  1GLO A;  2GHU A;  4ZUX U;  4PP2 E;  4WA6 A;  1MDW A;  4XUI A;  1STF E;  1NQC A;  4G54 A;  4X6I A;  3C9E A;  4BS5 A;  4YYQ A;  2DOS A;  1S4V A;  3IEJ A;  2NQA A;  4RF1 A;  2NQD B;  2E03 A;  2FT2 A;  3AI8 A;  4IUM A;  4N79 A;  4QRV A;  2YJB A;  4W5B A;  2DCA A;  1CPJ A;  3MHS A;  4AXL A;  3S3Q A;  3TRK A;  1SNK A;  1AU4 A;  2PBH A;  3OIS A;  2AYN A;  3BPM A;  1AYV A;  3IUT A;  3N4C A;  1YAL A;  1AU3 A;  1CTE A;  1NL6 A;  3B21 A;  3PBH A;  3RVV A;  1HUC B;  1PAD A;  1PPD A;  4QH6 A;  2AUZ A;  1IWD A;  2BTW B;  1KHQ A;  3BC3 A;  3IFU A;  2JRI A;  4KLB A;  3P5V A;  2O6X A;  2DZZ A;  2HHN A;  2CIO A;  1QOL A;  2GFO A;  4BOZ A;  3KSE A;  2FTD A;  3CH2 X;  2FQ9 A;  2DC9 A;  1PIP A;  4RY2 A;  5EF4 A;  1CB5 A;  3P5U A;  1DEU A;  5JH3 A;  1BQI A;  2R9C A;  3V6E A;  3TMP A;  1AU2 A;  3ZNH A;  2NQI A;  1U5I A;  3MP2 A;  2FYE A;  4N8W A;  3C0R A;  3S3R A;  3H7D A;  3BY4 A;  4BOU A;  3OVZ A;  4ZTB A;  2B1N A;  2ATO A;  3F75 A;  5CHV A;  4I05 A;  1SP4 B;  3W31 A;  3PRP A;  1THE A;  3BOW A;  4YYU A;  1YK8 A;  2G6D A;  4D8B A;  1PE6 A;  1QXP A;  3CH3 X;  4K7C A;  1EWP A;  2AVW A;  2AU1 A;  2OP3 A;  1Y4H A;  2HD5 A;  1ME4 A;  2OZ2 A;  4Q8G A;  2P0R A;  1ATK A;  4QRX A;  1BP4 A;  1U9V A;  2H7J A;  3E1Z B;  2C0Y A;  1DKI A;  4I04 A;  4QBB A;  5E6J A;  1KFX L;  2E01 A;  4R3D A;  2VHS A;  4OVZ B;  4CDD B;  2F1G A;  3IMA A;  5CVO B;  3WXG A;  1PXV A;  1EF7 A;  2HH5 A;  3N3K A;  2J7Q C;  1KHP A;  3MTN A;  2BU3 A;  1TL9 A;  3RVX A;  4Q8H A;  4BQV A;  4YYS A;  3W30 A;  1F2C A;  2P86 A;  3PW3 A;  3KFQ A;  3OF8 A;  4CZW A;  2YJ9 A;  2FO5 A;  2DJF B;  3KW9 A;  4YYW A;  4YVA A;  3PHX A;  3MOR A;  3BWK A;  2JTC A;  3BB7 A;  3H6S A;  1ME3 A;  2DC6 A;  1ZCM A;  2PNS A;  4HWY A;  1ZIV A;  4PI3 A;  2Z84 A;  3K9M A;  1K3B B;  2PAD A;  2JQF R;  3QT4 A;  1GMY A;  3O0U A;  1AIM A;  4DMX A;  1F29 A;  3OVX A;  4WUR A;  2DCB A;  1CJL A;  1X9Y A;  4RKX A;  5JZE A;  1GEC E;  4MI7 A;  3HD3 A;  6PAD A;  1CVZ A;  4W4U A;  1EWM A;  2HXZ A;  4PT5 A;  2YJ2 A;  2J7Q A;  3I3T A;  2BDZ A;  1YK7 A;  2R6N A;  2Y5B A;  3OQC A;  4MZO A;  4HXD B;  5A24 A;  1PCI A;  4OW0 A;  2AYO A;  4D8I A;  2XU1 A;  1PPN A;  4CDE B;  1MIR A;  3PSE A;  1AEC A;  2ARY A;  3K8U A;  3M99 A;  3CBJ A;  2G8J A;  5K16 A;  1KFU L;  3LFY A;  1AYU A;  4YYR A;  3MJ5 A;  5CVM A;  3BCN A;  3BBA A;  3RVW A;  1MS6 A;  1TLO A;  1EWO A;  3KX1 A;  2AIM A;  5CVN B;  1YT7 A;  3PDF A;  4MZS A;  2HWK A;  3O65 A;  4P6E A;  3LXS A;  2DC7 A;  4CDC B;  3WXE A;  1A6R A;  2DJG B;  2FE8 A;  2G8E A;  2DC8 A;  4I07 A;  1JQP A;  2OUL A;  1PPO A;  3F5V A;  3K24 A;  1Y08 A;  2R9F A;  2P7U A;  3U8E A;  4QRG A;  4P6G A;  9PAP A;  1QMY A;  3ERV A;  1ICF A;  1FH0 A;  2UZJ A;  4FJC A;  3PHW A;  2XU3 A;  2F7D A;  4PP1 A;  1U9Q X;  1CQD A;  2ACT A;  3I06 A;  1GCB A;  1BGO A;  1XKG A;  3KWB X;  2R9M A;  4BOQ A;  3H8C A;  1F2B A;  4X6H A;  4BS6 A;  3IHP A;  4XR7 A;  5CHT A;  1VSN A;  4PAD A;  2VHF A;  3E9S A;  4RNA A;  3HWN A;  3PT2 A; 
#chains in the Genus database with same CATH homology
 1EWL A;  3GCB A;  1BY8 A;  2E00 A;  1U9W A;  2R9N A;  4OEM A;  2XU4 A;  1AYW A;  4CDF B;  2NQG A;  1VJV A;  4DMY A;  3IOQ A;  1CV8 A;  1TU6 A;  3QJ3 A;  1NB5 A;  3HHA A;  3KKU A;  1W4T A;  1NPZ A;  3KWZ A;  1NB3 A;  3H89 A;  1MEG A;  3V6C A;  1U9X A;  2XU5 A;  1M6D A;  3TNX A;  4OEL A;  3D6S A;  4BSQ A;  2Y6E A;  8PCH A;  1QDQ A;  3BPF A;  2DCC A;  5JA7 A;  2JQG R;  1Q6K A;  2DCD A;  5FPW A;  3WXF A;  2YJC A;  3P5W A;  4BPV A;  3N3G A;  3IV2 A;  2PRE A;  2B1M A;  4AXM A;  3PNR A;  4NV7 A;  3HHI A;  2E02 A;  2FRQ A;  1PBH A;  4FIP A;  3O1G A;  4W5C A;  2G7Y A;  2IPP B;  3CBK A;  4N4Z A;  2FRA A;  5F02 A;  2VFB A;  7PCK A;  1CSB B;  4C5P A;  4X6J A;  2DZY A;  1MEM A;  1PPP A;  2BDL A;  1MHW A;  1POP A;  2YJ8 A;  3H8B A;  4YV8 A;  2AUX A;  3P5X A;  3USV A;  2WBF X;  1F2A A;  3QSD A;  1AU0 A;  3MHH A;  3ZUA A;  3OF9 A;  1DF0 A;  4FK5 A;  2IBI A;  5J94 A;  1ITO A;  5PAD A;  3NHE A;  2R9O A;  4MSX A;  4YYV A;  2AS8 A;  1O0E A;  2CB5 A;  2FUD A;  4BGF A;  3LTW A;  3B79 A;  5EGW A;  1CS8 A;  1YVB A;  3DF0 A;  1NLJ A;  1KXR A;  1GLO A;  2GHU A;  4ZUX U;  4PP2 E;  4WA6 A;  1MDW A;  4XUI A;  1STF E;  1NQC A;  4G54 A;  4X6I A;  3C9E A;  1E2T A;  4BS5 A;  4YYQ A;  1S4V A;  3IEJ A;  2NQA A;  2NQD B;  2E03 A;  2FT2 A;  3AI8 A;  4N79 A;  4QRV A;  4NV8 A;  2YJB A;  4W5B A;  2DCA A;  1CPJ A;  1GX3 A;  3MHS A;  4AXL A;  3S3Q A;  1SNK A;  3D9W A;  1AU4 A;  2PBH A;  3OIS A;  2AYN A;  3BPM A;  1AYV A;  3IUT A;  3N4C A;  1YAL A;  1AU3 A;  1CTE A;  1NL6 A;  3PBH A;  3RVV A;  1HUC B;  1PAD A;  1PPD A;  4QH6 A;  2AUZ A;  1IWD A;  1KHQ A;  3BC3 A;  4KLB A;  3P5V A;  2O6X A;  2DZZ A;  2HHN A;  2CIO A;  1QOL A;  2GFO A;  3KSE A;  2FTD A;  3CH2 X;  2FQ9 A;  2DC9 A;  1PIP A;  4RY2 A;  5EF4 A;  1CB5 A;  3P5U A;  1DEU A;  5JH3 A;  1BQI A;  2R9C A;  3V6E A;  1AU2 A;  2NQI A;  1U5I A;  2FYE A;  4N8W A;  3S3R A;  3H7D A;  3OVZ A;  2B1N A;  2ATO A;  3F75 A;  5CHV A;  4I05 A;  1SP4 B;  1THE A;  3BOW A;  4YYU A;  1YK8 A;  2G6D A;  1PE6 A;  4K7C A;  1QXP A;  3CH3 X;  1EWP A;  2AVW A;  2AU1 A;  2OP3 A;  1Y4H A;  2HD5 A;  1ME4 A;  2OZ2 A;  4Q8G A;  2P0R A;  1ATK A;  4QRX A;  1BP4 A;  1U9V A;  2H7J A;  3E1Z B;  2C0Y A;  4I04 A;  4QBB A;  1KFX L;  2E01 A;  2VHS A;  4CDD B;  2F1G A;  3IMA A;  5CVO B;  3WXG A;  1PXV A;  1EF7 A;  2HH5 A;  3N3K A;  1KHP A;  3MTN A;  1TL9 A;  3RVX A;  4Q8H A;  4BQV A;  4YYS A;  1F2C A;  2P86 A;  3PW3 A;  3KFQ A;  3OF8 A;  4CZW A;  2YJ9 A;  2FO5 A;  2DJF B;  3KW9 A;  4YYW A;  4YVA A;  3MOR A;  3BWK A;  2VFC A;  3H6S A;  1ME3 A;  2DC6 A;  1ZCM A;  2PNS A;  4HWY A;  1ZIV A;  4PI3 A;  3K9M A;  1K3B B;  2PAD A;  2JQF R;  3QT4 A;  1GMY A;  3O0U A;  1AIM A;  4DMX A;  1F29 A;  3OVX A;  2DCB A;  1CJL A;  4B55 A;  4GUZ A;  1X9Y A;  1GEC E;  3HD3 A;  6PAD A;  1CVZ A;  4W4U A;  1EWM A;  2HXZ A;  2YJ2 A;  3I3T A;  2BDZ A;  1YK7 A;  2R6N A;  2Y5B A;  4MZO A;  5A24 A;  1PCI A;  2AYO A;  2XU1 A;  1PPN A;  2BSZ A;  4CDE B;  1MIR A;  1AEC A;  2ARY A;  3K8U A;  3M99 A;  3CBJ A;  2G8J A;  5K16 A;  1KFU L;  3LFY A;  1AYU A;  4YYR A;  1W5R A;  5CVM A;  1W6F A;  3BCN A;  3RVW A;  1MS6 A;  1TLO A;  1EWO A;  3KX1 A;  2AIM A;  5CVN B;  1YT7 A;  3PDF A;  4P6E A;  3LXS A;  2DC7 A;  4CDC B;  3WXE A;  1A6R A;  2DJG B;  2G8E A;  2DC8 A;  4I07 A;  1JQP A;  2OUL A;  1PPO A;  3F5V A;  3K24 A;  1Y08 A;  2R9F A;  2P7U A;  3U8E A;  4QRG A;  4P6G A;  9PAP A;  1QMY A;  3ERV A;  1ICF A;  1FH0 A;  4FJC A;  2XU3 A;  2F7D A;  4PP1 A;  1U9Q X;  1CQD A;  2ACT A;  3I06 A;  1GCB A;  1BGO A;  1XKG A;  3KWB X;  2R9M A;  3H8C A;  1F2B A;  4X6H A;  4BS6 A;  3IHP A;  4XR7 A;  5CHT A;  1VSN A;  4PAD A;  2VHF A;  3HWN A;  4MZS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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