2XU4A

Cathepsin l with a nitrile inhibitor
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
220
structure length
217
Chain Sequence
APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Systematic Investigation of Halogen Bonding in Protein-Ligand Interactions.
pubmed doi rcsb
molecule keywords CATHEPSIN L1
molecule tags Hydrolase
source organism Homo sapiens
total genus 67
structure length 217
sequence length 220
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2010-10-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2xu4A00
4CZWA 1KHQA 2CB5A 4KLBA 1ATKA 2AYOA 1CJLA 2DCBA 4Q8HA 1BGOA 2FYEA 3OVZA 3IUTA 1PPDA 4I07A 3B79A 5JH3A 3E1ZB 3LFYA 1TLOA 4MZOA 1ITOA 3GCBA 3RVWA 2DZZA 2PNSA 4HWYA 3BC3A 3OF8A 4OELA 1HUCB 2H7JA 3BPFA 4I05A 3ZUAA 4PP1A 4YVAA 2GHUA 3BOWA 1YK7A 4CDCB 1STFE 2DCDA 4AXLA 1AU4A 1CPJA 2O6XA 1QDQA 3C9EA 4K7CA 3P5XA 3MORA 1CS8A 3KSEA 4FIPA 1POPA 3H89A 1Y08A 1BY8A 2XU3A 3O1GA 1VJVA 2HHNA 3PBHA 1QMYA 1GLOA 2DCCA 1PPPA 3O0UA 8PCHA 4PADA 2R9OA 2G7YA 3K24A 3MHHA 3BPMA 3KWBX 1F29A 5EF4A 5JA7A 2WBFX 1CV8A 4P6EA 6PADA 3HHIA 4BS5A 2HD5A 1MHWA 3USVA 1S4VA 1ZCMA 4AXMA 3P5VA 1M6DA 2DC9A 2F1GA 2NQDB 3HD3A 1U9QX 5J94A 4OEMA 3S3RA 3K9MA 1XKGA 2ATOA 1GMYA 2FO5A 4W4UA 3BWKA 4XR7A 3HHAA 2JQGR 2OP3A 4PI3A 1ZIVA 2AUZA 3MHSA 4BPVA 1GCBA 3D6SA 2E00A 1CVZA 3U8EA 2VHFA 1VSNA 3WXGA 2XU1A 2FTDA 4CDEB 3P5WA 3IMAA 1ICFA 4X6HA 1U9XA 1U9VA 2E02A 3QT4A 1QOLA 1KFUL 1EWOA 1DF0A 2AUXA 3F5VA 1EWMA 4CDFB 2OZ2A 2VHSA 2FT2A 1PIPA 1AYVA 1Y4HA 1AU0A 5PADA 1F2BA 3IEJA 2AVWA 2BDLA 1PPNA 1AU2A 1SP4B 2R9NA 1Q6KA 3WXFA 5CHVA 2AIMA 3M99A 1NLJA 4W5BA 3CBJA 4N4ZA 3I3TA 2P7UA 3CH2X 3LXSA 2ARYA 1F2AA 2R6NA 1IWDA 2DZYA 1A6RA 1CB5A 2YJBA 2GFOA 2B1NA 5CVMA 2AYNA 2G8EA 1NQCA 3IHPA 4CDDB 4YYRA 5K16A 4W5CA 5EGWA 2YJ2A 2E03A 1EWPA 4PP2E 4FK5A 4ZUXU 7PCKA 2Y5BA 4WA6A 2NQAA 5CHTA 4YYVA 1AYUA 2R9MA 3H7DA 2PADA 9PAPA 4QRXA 3KKUA 4FJCA 1MS6A 1PBHA 2HH5A 1NB3A 1NPZA 1X9YA 3OVXA 5A24A 1O0EA 2F7DA 2NQGA 3ERVA 2FRAA 1PADA 3BCNA 4BSQA 2YJCA 3H8BA 1NL6A 4QBBA 3V6EA 3PDFA 3AI8A 1BQIA 2AU1A 1JQPA 1U9WA 4BQVA 2NQIA 4YV8A 1MDWA 2C0YA 1KFXL 3DF0A 1MEGA 2DC8A 3PW3A 1ME4A 4BS6A 3RVXA 2FQ9A 2YJ8A 2JQFR 1EF7A 5CVNB 4RY2A 3MTNA 3NHEA 4MSXA 4DMXA 2PREA 1YK8A 3KWZA 2XU4A 4MZSA 1PXVA 2P86A 3CH3X 1YALA 2HXZA 1YVBA 3RVVA 3N3KA 3IOQA 1AIMA 3I06A 4I04A 4YYSA 3OF9A 3PNRA 1TL9A 2DC7A 3IV2A 3KW9A 1DEUA 2DJGB 4QRGA 1MEMA 1ME3A 4G54A 5CVOB 2G6DA 2PBHA 4QH6A 2FRQA 1PCIA 3KFQA 2OULA 4X6IA 2DC6A 3S3QA 1K3BB 2AS8A 3KX1A 1AECA 5F02A 3OISA 4YYQA 1THEA 4X6JA 2G8JA 2XU5A 1GECE 2BDZA 5FPWA 2IBIA 1CQDA 4QRVA 3F75A 1CSBB 4DMYA 1F2CA 1TU6A 3K8UA 1YT7A 1KHPA 4P6GA 3HWNA 2IPPB 2DJFB 1AYWA 4YYUA 1NB5A 3P5UA 1FH0A 2Y6EA 4YYWA 1PPOA 1BP4A 3CBKA 4Q8GA 2E01A 3N3GA 3H8CA 1EWLA 3V6CA 2ACTA 4N8WA 1U5IA 3N4CA 2YJ9A 2R9CA 1MIRA 1QXPA 3TNXA 1CTEA 3QJ3A 1AU3A 3QSDA 2B1MA 2DCAA 4XUIA 2P0RA 3H6SA 3WXEA 2CIOA 1PE6A 4N79A 2R9FA 1KXRA 2FUDA 1SNKA
chains in the Genus database with same CATH superfamily
4CZWA 1KHQA 2CB5A 4KLBA 1ATKA 2AYOA 1CJLA 2DCBA 4BOPA 4P16A 4Q8HA 1BGOA 2FYEA 3OVZA 3IUTA 1PPDA 3BBAA 4I07A 3B79A 5JH3A 3E1ZB 3LFYA 1TLOA 3GCBA 1ITOA 4MZOA 3RVWA 2DZZA 2PNSA 4HWYA 3PHUA 3BC3A 3OF8A 4OELA 1HUCB 2H7JA 3BPFA 4I05A 3ZUAA 4PP1A 4YVAA 2GHUA 4RF1A 3BOWA 1YK7A 4CDCB 1STFE 2DCDA 4AXLA 1AU4A 1CPJA 2O6XA 1QDQA 3C9EA 2JRIA 4K7CA 3P5XA 3MORA 3BY4A 1CS8A 3BB7A 3KSEA 4FIPA 1POPA 3H89A 1Y08A 4BOUA 1BY8A 4M0WA 2XU3A 3RNVA 3O1GA 1VJVA 2HHNA 3PBHA 1QMYA 1GLOA 2DCCA 1PPPA 3O0UA 8PCHA 4PADA 2R9OA 2G7YA 3K24A 3MHHA 3BPMA 3KWBX 4ZTBA 1F29A 5EF4A 4IUMA 5JA7A 2WBFX 1CV8A 4P6EA 6PADA 3HHIA 4BS5A 3PSEA 2HD5A 1MHWA 3USVA 4MI7A 1S4VA 1ZCMA 4AXMA 4D8IA 3P5VA 1M6DA 2DC9A 2F1GA 2BU3A 2NQDB 3HD3A 1U9QX 3C0RA 4OEMA 5J94A 3S3RA 3K9MA 4OW0A 1XKGA 2UZJA 3PHWA 2ATOA 1GMYA 2FO5A 4W4UA 3BWKA 4XR7A 3HHAA 2JQGR 2OP3A 4PI3A 1ZIVA 4D8EA 2AUZA 3MHSA 4BPVA 4WURA 1GCBA 3D6SA 2E00A 3W30A 1CVZA 3U8EA 2VHFA 1VSNA 3WXGA 2XU1A 4MM3B 4XZXA 2FTDA 4GUAA 4CDEB 3P5WA 3IMAA 5E6JA 2J7QA 1ICFA 4X6HA 5JZEA 1U9XA 1U9VA 2E02A 3QT4A 1QOLA 3TRKA 1KFUL 1EWOA 1DF0A 2AUXA 3F5VA 1EWMA 4CDFB 2OZ2A 2VHSA 2FT2A 1PIPA 1AYVA 1Y4HA 4R3DA 1AU0A 3PRMA 5PADA 2DOSA 1F2BA 3IEJA 2AVWA 2BDLA 1PPNA 1AU2A 1SP4B 2R9NA 1Q6KA 3WXFA 5CHVA 2AIMA 3M99A 1NLJA 4W5BA 4OVZA 3CBJA 4N4ZA 3I3TA 2P7UA 3CH2X 3LXSA 2ARYA 1F2AA 2R6NA 1IWDA 2DZYA 1A6RA 1CB5A 2YJBA 2GFOA 2B1NA 5CVMA 2AYNA 2G8EA 1NQCA 3IHPA 2BTWB 4CDDB 4YYRA 5K16A 3MP2A 4W5CA 1UKFA 5EGWA 2YJ2A 2E03A 1EWPA 4PP2E 4FK5A 4BOSA 4ZUXU 7PCKA 2Y5BA 1DKIA 4WA6A 2NQAA 5CHTA 4YYVA 1AYUA 2R9MA 3H7DA 4D8BA 4REZA 2PADA 9PAPA 4QRXA 3KKUA 4FJCA 1MS6A 1PBHA 2HH5A 1NB3A 1NPZA 1X9YA 4PT5A 3OVXA 5A24A 1O0EA 2F7DA 2NQGA 3ERVA 3MJ5A 2FRAA 1PADA 3BCNA 4BSQA 2YJCA 3IFUA 3H8BA 1NL6A 4QBBA 3V6EA 3PDFA 3AI8A 1BQIA 2AU1A 1JQPA 1U9WA 4BQVA 2NQIA 4YV8A 1MDWA 2C0YA 1KFXL 3DF0A 1MEGA 2JTCA 2DC8A 3W31A 3PW3A 1ME4A 5KO3A 2HWKA 4BS6A 3RVXA 3E9SA 3MTVA 2FQ9A 2YJ8A 2FE8A 2JQFR 1EF7A 5CVNB 4RY2A 3MTNA 3NHEA 4MSXA 4DMXA 5EZSA 2PREA 4BOZA 1YK8A 3KWZA 2XU4A 4MZSA 1PXVA 2P86A 3CH3X 4HXDB 1YALA 2HXZA 1YVBA 3RVVA 3N3KA 1PVJA 2Z84A 3IOQA 1AIMA 3I06A 4I04A 4YYSA 3ZNHA 3OF9A 3PNRA 3TMPA 1TL9A 2DC7A 4RKXA 3IV2A 3KW9A 1DEUA 2DJGB 4QRGA 1MEMA 1ME3A 4G54A 5CVOB 2G6DA 2PBHA 4QH6A 2FRQA 1PCIA 3PHXA 3KFQA 2OULA 4X6IA 4BOQA 2DC6A 3S3QA 1K3BB 2AS8A 4OVZB 3KX1A 1AECA 5F02A 3OISA 4YYQA 1THEA 4X6JA 2G8JA 2XU5A 3O65A 4RNAA 1GECE 2BDZA 4RF0A 5FPWA 5EZQA 2IBIA 1CQDA 4QRVA 3F75A 1CSBB 4DMYA 1F2CA 2BTWA 1TU6A 2AGAA 3K8UA 1YT7A 1KHPA 4P6GA 3HWNA 2IPPB 2DJFB 1AYWA 4A5UA 4YYUA 1NB5A 3P5UA 3OQCA 1FH0A 2Y6EA 4IP3A 4YYWA 3PRPA 1PPOA 1BP4A 3CBKA 4Q8GA 2E01A 3N3GA 3H8CA 1EWLA 3V6CA 2ACTA 1YZBA 4N8WA 1U5IA 3N4CA 2YJ9A 2R9CA 3B21A 1MIRA 1QXPA 3TNXA 1CTEA 3QJ3A 3PT2A 1AU3A 3QSDA 2B1MA 2DCAA 4XUIA 2P0RA 3H6SA 3WXEA 2CIOA 1PE6A 4N79A 2J7QC 2R9FA 1KXRA 2FUDA 1SNKA
chains in the Genus database with same CATH topology
4CZWA 1KHQA 2CB5A 4KLBA 1ATKA 2AYOA 1CJLA 2DCBA 4Q8HA 1BGOA 2FYEA 3OVZA 3IUTA 1E2TA 1PPDA 4I07A 3B79A 5JH3A 3E1ZB 3LFYA 1TLOA 4MZOA 1ITOA 3GCBA 3RVWA 2DZZA 2PNSA 4HWYA 3BC3A 3OF8A 4OELA 1HUCB 2H7JA 3BPFA 4I05A 3ZUAA 4PP1A 4YVAA 2GHUA 3BOWA 1YK7A 4B55A 1STFE 4CDCB 2DCDA 4AXLA 1AU4A 1CPJA 2O6XA 1QDQA 3C9EA 4K7CA 3P5XA 3MORA 1CS8A 3KSEA 4FIPA 1POPA 3H89A 1Y08A 1BY8A 2XU3A 3O1GA 1VJVA 2HHNA 3PBHA 1QMYA 1GLOA 2DCCA 1PPPA 3O0UA 8PCHA 4PADA 2R9OA 2G7YA 3K24A 3MHHA 3BPMA 3KWBX 1F29A 5EF4A 5JA7A 2WBFX 4GUZA 1CV8A 4P6EA 6PADA 3HHIA 4BS5A 2HD5A 1MHWA 3USVA 1S4VA 1ZCMA 4AXMA 3P5VA 1M6DA 2DC9A 2F1GA 2NQDB 3HD3A 1U9QX 5J94A 4OEMA 3S3RA 3K9MA 1XKGA 2ATOA 1GMYA 2VFCA 2FO5A 4W4UA 1W6FA 3BWKA 4XR7A 3HHAA 2JQGR 2OP3A 4PI3A 1ZIVA 2AUZA 3MHSA 4BPVA 1GCBA 3D6SA 2E00A 1CVZA 3U8EA 4NV8A 2BSZA 2VHFA 1VSNA 3WXGA 3LTWA 2XU1A 2FTDA 4CDEB 3P5WA 3IMAA 1ICFA 4X6HA 1U9XA 1U9VA 2E02A 3QT4A 1QOLA 1KFUL 1EWOA 1DF0A 2AUXA 1W5RA 1EWMA 3F5VA 4CDFB 2OZ2A 2VHSA 2FT2A 1PIPA 1AYVA 1Y4HA 1AU0A 5PADA 1F2BA 3IEJA 2AVWA 2BDLA 1PPNA 1AU2A 1SP4B 2R9NA 1Q6KA 3WXFA 5CHVA 2AIMA 3M99A 1NLJA 4W5BA 3CBJA 4N4ZA 3I3TA 2P7UA 3CH2X 3LXSA 2ARYA 1F2AA 2R6NA 1IWDA 2DZYA 1A6RA 1CB5A 2YJBA 2GFOA 2B1NA 5CVMA 2AYNA 2G8EA 1NQCA 3IHPA 4CDDB 4YYRA 5K16A 4W5CA 3D9WA 5EGWA 2YJ2A 4BGFA 2E03A 1EWPA 4PP2E 4FK5A 4ZUXU 7PCKA 2Y5BA 4WA6A 2NQAA 5CHTA 4YYVA 1AYUA 2R9MA 3H7DA 2PADA 9PAPA 4QRXA 3KKUA 4FJCA 1MS6A 1PBHA 2HH5A 1NB3A 1NPZA 1X9YA 3OVXA 5A24A 1O0EA 2F7DA 2NQGA 3ERVA 2FRAA 1PADA 3BCNA 4BSQA 2YJCA 1W4TA 3H8BA 4NV7A 1NL6A 4QBBA 3V6EA 3PDFA 3AI8A 1BQIA 2AU1A 1JQPA 1U9WA 4BQVA 2NQIA 4YV8A 1MDWA 2C0YA 1KFXL 3DF0A 1MEGA 2DC8A 3PW3A 1ME4A 4BS6A 3RVXA 2FQ9A 2YJ8A 2JQFR 1EF7A 5CVNB 4RY2A 3MTNA 3NHEA 4MSXA 4DMXA 2PREA 1YK8A 3KWZA 2XU4A 4MZSA 1PXVA 2P86A 3CH3X 1YALA 2HXZA 1YVBA 3RVVA 3N3KA 3IOQA 1AIMA 3I06A 4I04A 4YYSA 3OF9A 3PNRA 4C5PA 1TL9A 2DC7A 3IV2A 3KW9A 1DEUA 2DJGB 4QRGA 1MEMA 1ME3A 4G54A 5CVOB 2G6DA 2PBHA 4QH6A 2FRQA 1PCIA 3KFQA 2OULA 4X6IA 2DC6A 3S3QA 1K3BB 2AS8A 3KX1A 1AECA 5F02A 3OISA 4YYQA 1THEA 4X6JA 2G8JA 2XU5A 1GECE 2BDZA 5FPWA 2IBIA 1CQDA 4QRVA 3F75A 1CSBB 4DMYA 2VFBA 1F2CA 1TU6A 3K8UA 1YT7A 1KHPA 4P6GA 3HWNA 1GX3A 2IPPB 2DJFB 1AYWA 4YYUA 1NB5A 3P5UA 1FH0A 2Y6EA 4YYWA 1PPOA 1BP4A 3CBKA 4Q8GA 2E01A 3N3GA 3H8CA 1EWLA 3V6CA 2ACTA 4N8WA 1U5IA 3N4CA 2YJ9A 2R9CA 1MIRA 1QXPA 3TNXA 1CTEA 3QJ3A 1AU3A 3QSDA 2B1MA 2DCAA 4XUIA 2P0RA 3H6SA 3WXEA 2CIOA 1PE6A 4N79A 2R9FA 1KXRA 2FUDA 1SNKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CZW A;  1KHQ A;  2CB5 A;  4KLB A;  1ATK A;  2AYO A;  1CJL A;  2DCB A;  4Q8H A;  1BGO A;  2FYE A;  3OVZ A;  3IUT A;  1PPD A;  4I07 A;  3B79 A;  5JH3 A;  3E1Z B;  3LFY A;  1TLO A;  4MZO A;  1ITO A;  3GCB A;  3RVW A;  2DZZ A;  2PNS A;  4HWY A;  3BC3 A;  3OF8 A;  4OEL A;  1HUC B;  2H7J A;  3BPF A;  4I05 A;  3ZUA A;  4PP1 A;  4YVA A;  2GHU A;  3BOW A;  1YK7 A;  4CDC B;  1STF E;  2DCD A;  4AXL A;  1AU4 A;  1CPJ A;  2O6X A;  1QDQ A;  3C9E A;  4K7C A;  3P5X A;  3MOR A;  1CS8 A;  3KSE A;  4FIP A;  1POP A;  3H89 A;  1Y08 A;  1BY8 A;  2XU3 A;  3O1G A;  1VJV A;  2HHN A;  3PBH A;  1QMY A;  1GLO A;  2DCC A;  1PPP A;  3O0U A;  8PCH A;  4PAD A;  2R9O A;  2G7Y A;  3K24 A;  3MHH A;  3BPM A;  3KWB X;  1F29 A;  5EF4 A;  5JA7 A;  2WBF X;  1CV8 A;  4P6E A;  6PAD A;  3HHI A;  4BS5 A;  2HD5 A;  1MHW A;  3USV A;  1S4V A;  1ZCM A;  4AXM A;  3P5V A;  1M6D A;  2DC9 A;  2F1G A;  2NQD B;  3HD3 A;  1U9Q X;  5J94 A;  4OEM A;  3S3R A;  3K9M A;  1XKG A;  2ATO A;  1GMY A;  2FO5 A;  4W4U A;  3BWK A;  4XR7 A;  3HHA A;  2JQG R;  2OP3 A;  4PI3 A;  1ZIV A;  2AUZ A;  3MHS A;  4BPV A;  1GCB A;  3D6S A;  2E00 A;  1CVZ A;  3U8E A;  2VHF A;  1VSN A;  3WXG A;  2XU1 A;  2FTD A;  4CDE B;  3P5W A;  3IMA A;  1ICF A;  4X6H A;  1U9X A;  1U9V A;  2E02 A;  3QT4 A;  1QOL A;  1KFU L;  1EWO A;  1DF0 A;  2AUX A;  3F5V A;  1EWM A;  4CDF B;  2OZ2 A;  2VHS A;  2FT2 A;  1PIP A;  1AYV A;  1Y4H A;  1AU0 A;  5PAD A;  1F2B A;  3IEJ A;  2AVW A;  2BDL A;  1PPN A;  1AU2 A;  1SP4 B;  2R9N A;  1Q6K A;  3WXF A;  5CHV A;  2AIM A;  3M99 A;  1NLJ A;  4W5B A;  3CBJ A;  4N4Z A;  3I3T A;  2P7U A;  3CH2 X;  3LXS A;  2ARY A;  1F2A A;  2R6N A;  1IWD A;  2DZY A;  1A6R A;  1CB5 A;  2YJB A;  2GFO A;  2B1N A;  5CVM A;  2AYN A;  2G8E A;  1NQC A;  3IHP A;  4CDD B;  4YYR A;  5K16 A;  4W5C A;  5EGW A;  2YJ2 A;  2E03 A;  1EWP A;  4PP2 E;  4FK5 A;  4ZUX U;  7PCK A;  2Y5B A;  4WA6 A;  2NQA A;  5CHT A;  4YYV A;  1AYU A;  2R9M A;  3H7D A;  2PAD A;  9PAP A;  4QRX A;  3KKU A;  4FJC A;  1MS6 A;  1PBH A;  2HH5 A;  1NB3 A;  1NPZ A;  1X9Y A;  3OVX A;  5A24 A;  1O0E A;  2F7D A;  2NQG A;  3ERV A;  2FRA A;  1PAD A;  3BCN A;  4BSQ A;  2YJC A;  3H8B A;  1NL6 A;  4QBB A;  3V6E A;  3PDF A;  3AI8 A;  1BQI A;  2AU1 A;  1JQP A;  1U9W A;  4BQV A;  2NQI A;  4YV8 A;  1MDW A;  2C0Y A;  1KFX L;  3DF0 A;  1MEG A;  2DC8 A;  3PW3 A;  1ME4 A;  4BS6 A;  3RVX A;  2FQ9 A;  2YJ8 A;  2JQF R;  1EF7 A;  5CVN B;  4RY2 A;  3MTN A;  3NHE A;  4MSX A;  4DMX A;  2PRE A;  1YK8 A;  3KWZ A;  2XU4 A;  4MZS A;  1PXV A;  2P86 A;  3CH3 X;  1YAL A;  2HXZ A;  1YVB A;  3RVV A;  3N3K A;  3IOQ A;  1AIM A;  3I06 A;  4I04 A;  4YYS A;  3OF9 A;  3PNR A;  1TL9 A;  2DC7 A;  3IV2 A;  3KW9 A;  1DEU A;  2DJG B;  4QRG A;  1MEM A;  1ME3 A;  4G54 A;  5CVO B;  2G6D A;  2PBH A;  4QH6 A;  2FRQ A;  1PCI A;  3KFQ A;  2OUL A;  4X6I A;  2DC6 A;  3S3Q A;  1K3B B;  2AS8 A;  3KX1 A;  1AEC A;  5F02 A;  3OIS A;  4YYQ A;  1THE A;  4X6J A;  2G8J A;  2XU5 A;  1GEC E;  2BDZ A;  5FPW A;  2IBI A;  1CQD A;  4QRV A;  3F75 A;  1CSB B;  4DMY A;  1F2C A;  1TU6 A;  3K8U A;  1YT7 A;  1KHP A;  4P6G A;  3HWN A;  2IPP B;  2DJF B;  1AYW A;  4YYU A;  1NB5 A;  3P5U A;  1FH0 A;  2Y6E A;  4YYW A;  1PPO A;  1BP4 A;  3CBK A;  4Q8G A;  2E01 A;  3N3G A;  3H8C A;  1EWL A;  3V6C A;  2ACT A;  4N8W A;  1U5I A;  3N4C A;  2YJ9 A;  2R9C A;  1MIR A;  1QXP A;  3TNX A;  1CTE A;  3QJ3 A;  1AU3 A;  3QSD A;  2B1M A;  2DCA A;  4XUI A;  2P0R A;  3H6S A;  3WXE A;  2CIO A;  1PE6 A;  4N79 A;  2R9F A;  1KXR A;  2FUD A;  1SNK A; 
#chains in the Genus database with same CATH topology
 4CZW A;  1KHQ A;  2CB5 A;  4KLB A;  1ATK A;  2AYO A;  1CJL A;  2DCB A;  4BOP A;  4P16 A;  4Q8H A;  1BGO A;  2FYE A;  3OVZ A;  3IUT A;  1PPD A;  3BBA A;  4I07 A;  3B79 A;  5JH3 A;  3E1Z B;  3LFY A;  1TLO A;  3GCB A;  1ITO A;  4MZO A;  3RVW A;  2DZZ A;  2PNS A;  4HWY A;  3PHU A;  3BC3 A;  3OF8 A;  4OEL A;  1HUC B;  2H7J A;  3BPF A;  4I05 A;  3ZUA A;  4PP1 A;  4YVA A;  2GHU A;  4RF1 A;  3BOW A;  1YK7 A;  4CDC B;  1STF E;  2DCD A;  4AXL A;  1AU4 A;  1CPJ A;  2O6X A;  1QDQ A;  3C9E A;  2JRI A;  4K7C A;  3P5X A;  3MOR A;  3BY4 A;  1CS8 A;  3BB7 A;  3KSE A;  4FIP A;  1POP A;  3H89 A;  1Y08 A;  4BOU A;  1BY8 A;  4M0W A;  2XU3 A;  3RNV A;  3O1G A;  1VJV A;  2HHN A;  3PBH A;  1QMY A;  1GLO A;  2DCC A;  1PPP A;  3O0U A;  8PCH A;  4PAD A;  2R9O A;  2G7Y A;  3K24 A;  3MHH A;  3BPM A;  3KWB X;  4ZTB A;  1F29 A;  5EF4 A;  4IUM A;  5JA7 A;  2WBF X;  1CV8 A;  4P6E A;  6PAD A;  3HHI A;  4BS5 A;  3PSE A;  2HD5 A;  1MHW A;  3USV A;  4MI7 A;  1S4V A;  1ZCM A;  4AXM A;  4D8I A;  3P5V A;  1M6D A;  2DC9 A;  2F1G A;  2BU3 A;  2NQD B;  3HD3 A;  1U9Q X;  3C0R A;  4OEM A;  5J94 A;  3S3R A;  3K9M A;  4OW0 A;  1XKG A;  2UZJ A;  3PHW A;  2ATO A;  1GMY A;  2FO5 A;  4W4U A;  3BWK A;  4XR7 A;  3HHA A;  2JQG R;  2OP3 A;  4PI3 A;  1ZIV A;  4D8E A;  2AUZ A;  3MHS A;  4BPV A;  4WUR A;  1GCB A;  3D6S A;  2E00 A;  3W30 A;  1CVZ A;  3U8E A;  2VHF A;  1VSN A;  3WXG A;  2XU1 A;  4MM3 B;  4XZX A;  2FTD A;  4GUA A;  4CDE B;  3P5W A;  3IMA A;  5E6J A;  2J7Q A;  1ICF A;  4X6H A;  5JZE A;  1U9X A;  1U9V A;  2E02 A;  3QT4 A;  1QOL A;  3TRK A;  1KFU L;  1EWO A;  1DF0 A;  2AUX A;  3F5V A;  1EWM A;  4CDF B;  2OZ2 A;  2VHS A;  2FT2 A;  1PIP A;  1AYV A;  1Y4H A;  4R3D A;  1AU0 A;  3PRM A;  5PAD A;  2DOS A;  1F2B A;  3IEJ A;  2AVW A;  2BDL A;  1PPN A;  1AU2 A;  1SP4 B;  2R9N A;  1Q6K A;  3WXF A;  5CHV A;  2AIM A;  3M99 A;  1NLJ A;  4W5B A;  4OVZ A;  3CBJ A;  4N4Z A;  3I3T A;  2P7U A;  3CH2 X;  3LXS A;  2ARY A;  1F2A A;  2R6N A;  1IWD A;  2DZY A;  1A6R A;  1CB5 A;  2YJB A;  2GFO A;  2B1N A;  5CVM A;  2AYN A;  2G8E A;  1NQC A;  3IHP A;  2BTW B;  4CDD B;  4YYR A;  5K16 A;  3MP2 A;  4W5C A;  1UKF A;  5EGW A;  2YJ2 A;  2E03 A;  1EWP A;  4PP2 E;  4FK5 A;  4BOS A;  4ZUX U;  7PCK A;  2Y5B A;  1DKI A;  4WA6 A;  2NQA A;  5CHT A;  4YYV A;  1AYU A;  2R9M A;  3H7D A;  4D8B A;  4REZ A;  2PAD A;  9PAP A;  4QRX A;  3KKU A;  4FJC A;  1MS6 A;  1PBH A;  2HH5 A;  1NB3 A;  1NPZ A;  1X9Y A;  4PT5 A;  3OVX A;  5A24 A;  1O0E A;  2F7D A;  2NQG A;  3ERV A;  3MJ5 A;  2FRA A;  1PAD A;  3BCN A;  4BSQ A;  2YJC A;  3IFU A;  3H8B A;  1NL6 A;  4QBB A;  3V6E A;  3PDF A;  3AI8 A;  1BQI A;  2AU1 A;  1JQP A;  1U9W A;  4BQV A;  2NQI A;  4YV8 A;  1MDW A;  2C0Y A;  1KFX L;  3DF0 A;  1MEG A;  2JTC A;  2DC8 A;  3W31 A;  3PW3 A;  1ME4 A;  5KO3 A;  2HWK A;  4BS6 A;  3RVX A;  3E9S A;  3MTV A;  2FQ9 A;  2YJ8 A;  2FE8 A;  2JQF R;  1EF7 A;  5CVN B;  4RY2 A;  3MTN A;  3NHE A;  4MSX A;  4DMX A;  5EZS A;  2PRE A;  4BOZ A;  1YK8 A;  3KWZ A;  2XU4 A;  4MZS A;  1PXV A;  2P86 A;  3CH3 X;  4HXD B;  1YAL A;  2HXZ A;  1YVB A;  3RVV A;  3N3K A;  1PVJ A;  2Z84 A;  3IOQ A;  1AIM A;  3I06 A;  4I04 A;  4YYS A;  3ZNH A;  3OF9 A;  3PNR A;  3TMP A;  1TL9 A;  2DC7 A;  4RKX A;  3IV2 A;  3KW9 A;  1DEU A;  2DJG B;  4QRG A;  1MEM A;  1ME3 A;  4G54 A;  5CVO B;  2G6D A;  2PBH A;  4QH6 A;  2FRQ A;  1PCI A;  3PHX A;  3KFQ A;  2OUL A;  4X6I A;  4BOQ A;  2DC6 A;  3S3Q A;  1K3B B;  2AS8 A;  4OVZ B;  3KX1 A;  1AEC A;  5F02 A;  3OIS A;  4YYQ A;  1THE A;  4X6J A;  2G8J A;  2XU5 A;  3O65 A;  4RNA A;  1GEC E;  2BDZ A;  4RF0 A;  5FPW A;  5EZQ A;  2IBI A;  1CQD A;  4QRV A;  3F75 A;  1CSB B;  4DMY A;  1F2C A;  2BTW A;  1TU6 A;  2AGA A;  3K8U A;  1YT7 A;  1KHP A;  4P6G A;  3HWN A;  2IPP B;  2DJF B;  1AYW A;  4A5U A;  4YYU A;  1NB5 A;  3P5U A;  3OQC A;  1FH0 A;  2Y6E A;  4IP3 A;  4YYW A;  3PRP A;  1PPO A;  1BP4 A;  3CBK A;  4Q8G A;  2E01 A;  3N3G A;  3H8C A;  1EWL A;  3V6C A;  2ACT A;  1YZB A;  4N8W A;  1U5I A;  3N4C A;  2YJ9 A;  2R9C A;  3B21 A;  1MIR A;  1QXP A;  3TNX A;  1CTE A;  3QJ3 A;  3PT2 A;  1AU3 A;  3QSD A;  2B1M A;  2DCA A;  4XUI A;  2P0R A;  3H6S A;  3WXE A;  2CIO A;  1PE6 A;  4N79 A;  2J7Q C;  2R9F A;  1KXR A;  2FUD A;  1SNK A; 
#chains in the Genus database with same CATH homology
 4CZW A;  1KHQ A;  2CB5 A;  4KLB A;  1ATK A;  2AYO A;  1CJL A;  2DCB A;  4Q8H A;  1BGO A;  2FYE A;  3OVZ A;  3IUT A;  1E2T A;  1PPD A;  4I07 A;  3B79 A;  5JH3 A;  3E1Z B;  3LFY A;  1TLO A;  4MZO A;  1ITO A;  3GCB A;  3RVW A;  2DZZ A;  2PNS A;  4HWY A;  3BC3 A;  3OF8 A;  4OEL A;  1HUC B;  2H7J A;  3BPF A;  4I05 A;  3ZUA A;  4PP1 A;  4YVA A;  2GHU A;  3BOW A;  1YK7 A;  4B55 A;  1STF E;  4CDC B;  2DCD A;  4AXL A;  1AU4 A;  1CPJ A;  2O6X A;  1QDQ A;  3C9E A;  4K7C A;  3P5X A;  3MOR A;  1CS8 A;  3KSE A;  4FIP A;  1POP A;  3H89 A;  1Y08 A;  1BY8 A;  2XU3 A;  3O1G A;  1VJV A;  2HHN A;  3PBH A;  1QMY A;  1GLO A;  2DCC A;  1PPP A;  3O0U A;  8PCH A;  4PAD A;  2R9O A;  2G7Y A;  3K24 A;  3MHH A;  3BPM A;  3KWB X;  1F29 A;  5EF4 A;  5JA7 A;  2WBF X;  4GUZ A;  1CV8 A;  4P6E A;  6PAD A;  3HHI A;  4BS5 A;  2HD5 A;  1MHW A;  3USV A;  1S4V A;  1ZCM A;  4AXM A;  3P5V A;  1M6D A;  2DC9 A;  2F1G A;  2NQD B;  3HD3 A;  1U9Q X;  5J94 A;  4OEM A;  3S3R A;  3K9M A;  1XKG A;  2ATO A;  1GMY A;  2VFC A;  2FO5 A;  4W4U A;  1W6F A;  3BWK A;  4XR7 A;  3HHA A;  2JQG R;  2OP3 A;  4PI3 A;  1ZIV A;  2AUZ A;  3MHS A;  4BPV A;  1GCB A;  3D6S A;  2E00 A;  1CVZ A;  3U8E A;  4NV8 A;  2BSZ A;  2VHF A;  1VSN A;  3WXG A;  3LTW A;  2XU1 A;  2FTD A;  4CDE B;  3P5W A;  3IMA A;  1ICF A;  4X6H A;  1U9X A;  1U9V A;  2E02 A;  3QT4 A;  1QOL A;  1KFU L;  1EWO A;  1DF0 A;  2AUX A;  1W5R A;  1EWM A;  3F5V A;  4CDF B;  2OZ2 A;  2VHS A;  2FT2 A;  1PIP A;  1AYV A;  1Y4H A;  1AU0 A;  5PAD A;  1F2B A;  3IEJ A;  2AVW A;  2BDL A;  1PPN A;  1AU2 A;  1SP4 B;  2R9N A;  1Q6K A;  3WXF A;  5CHV A;  2AIM A;  3M99 A;  1NLJ A;  4W5B A;  3CBJ A;  4N4Z A;  3I3T A;  2P7U A;  3CH2 X;  3LXS A;  2ARY A;  1F2A A;  2R6N A;  1IWD A;  2DZY A;  1A6R A;  1CB5 A;  2YJB A;  2GFO A;  2B1N A;  5CVM A;  2AYN A;  2G8E A;  1NQC A;  3IHP A;  4CDD B;  4YYR A;  5K16 A;  4W5C A;  3D9W A;  5EGW A;  2YJ2 A;  4BGF A;  2E03 A;  1EWP A;  4PP2 E;  4FK5 A;  4ZUX U;  7PCK A;  2Y5B A;  4WA6 A;  2NQA A;  5CHT A;  4YYV A;  1AYU A;  2R9M A;  3H7D A;  2PAD A;  9PAP A;  4QRX A;  3KKU A;  4FJC A;  1MS6 A;  1PBH A;  2HH5 A;  1NB3 A;  1NPZ A;  1X9Y A;  3OVX A;  5A24 A;  1O0E A;  2F7D A;  2NQG A;  3ERV A;  2FRA A;  1PAD A;  3BCN A;  4BSQ A;  2YJC A;  1W4T A;  3H8B A;  4NV7 A;  1NL6 A;  4QBB A;  3V6E A;  3PDF A;  3AI8 A;  1BQI A;  2AU1 A;  1JQP A;  1U9W A;  4BQV A;  2NQI A;  4YV8 A;  1MDW A;  2C0Y A;  1KFX L;  3DF0 A;  1MEG A;  2DC8 A;  3PW3 A;  1ME4 A;  4BS6 A;  3RVX A;  2FQ9 A;  2YJ8 A;  2JQF R;  1EF7 A;  5CVN B;  4RY2 A;  3MTN A;  3NHE A;  4MSX A;  4DMX A;  2PRE A;  1YK8 A;  3KWZ A;  2XU4 A;  4MZS A;  1PXV A;  2P86 A;  3CH3 X;  1YAL A;  2HXZ A;  1YVB A;  3RVV A;  3N3K A;  3IOQ A;  1AIM A;  3I06 A;  4I04 A;  4YYS A;  3OF9 A;  3PNR A;  4C5P A;  1TL9 A;  2DC7 A;  3IV2 A;  3KW9 A;  1DEU A;  2DJG B;  4QRG A;  1MEM A;  1ME3 A;  4G54 A;  5CVO B;  2G6D A;  2PBH A;  4QH6 A;  2FRQ A;  1PCI A;  3KFQ A;  2OUL A;  4X6I A;  2DC6 A;  3S3Q A;  1K3B B;  2AS8 A;  3KX1 A;  1AEC A;  5F02 A;  3OIS A;  4YYQ A;  1THE A;  4X6J A;  2G8J A;  2XU5 A;  1GEC E;  2BDZ A;  5FPW A;  2IBI A;  1CQD A;  4QRV A;  3F75 A;  1CSB B;  4DMY A;  2VFB A;  1F2C A;  1TU6 A;  3K8U A;  1YT7 A;  1KHP A;  4P6G A;  3HWN A;  1GX3 A;  2IPP B;  2DJF B;  1AYW A;  4YYU A;  1NB5 A;  3P5U A;  1FH0 A;  2Y6E A;  4YYW A;  1PPO A;  1BP4 A;  3CBK A;  4Q8G A;  2E01 A;  3N3G A;  3H8C A;  1EWL A;  3V6C A;  2ACT A;  4N8W A;  1U5I A;  3N4C A;  2YJ9 A;  2R9C A;  1MIR A;  1QXP A;  3TNX A;  1CTE A;  3QJ3 A;  1AU3 A;  3QSD A;  2B1M A;  2DCA A;  4XUI A;  2P0R A;  3H6S A;  3WXE A;  2CIO A;  1PE6 A;  4N79 A;  2R9F A;  1KXR A;  2FUD A;  1SNK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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