2XU4A

Cathepsin l with a nitrile inhibitor
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
220
structure length
217
Chain Sequence
b'APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords CATHEPSIN L1
publication title Systematic Investigation of Halogen Bonding in Protein-Ligand Interactions.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 67
structure length 217
sequence length 220
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2010-10-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2xu4A00
4PADA 2PADA 2B1NA 2PNSA 5PADA 1GMYA 2NQDB 4MSXA 2GHUA 1ITOA 2CIOA 3KSEA 2OP3A 3HWNA 3U8EA 1CTEA 1QXPA 3K9MA 1TL9A 4YYWA 1U9WA 5K16A 2HH5A 2IPPB 1GECE 1NQCA 2AYNA 4QBBA 2ACTA 2BDZA 3BCNA 3LXSA 4KLBA 1AECA 1EWPA 2DC8A 1ICFA 3LFYA 3RVVA 1AU4A 1CPJA 1KFUL 3MHHA 1PPOA 3P5XA 1CVZA 2R9OA 4QH6A 3BOWA 1TLOA 2FYEA 2HHNA 1PE6A 4QRVA 4CDCB 3CH3X 3OVXA 4QRXA 4WA6A 3OF9A 1IWDA 3OF8A 3DF0A 2PBHA 2G8EA 1ME3A 1PPDA 2R9CA 4BQVA 2VHSA 1MIRA 1ATKA 2FRAA 3F5VA 3B79A 4BS5A 3S3QA 1SNKA 4BPVA 1YK8A 4HWYA 4CDFB 1F29A 2R9FA 1AYWA 2F1GA 4CDEB 5CVMA 3QJ3A 4BSQA 3V6CA 1AIMA 2BDLA 1AU2A 3MORA 1M6DA 1KXRA 2NQIA 1KHPA 1PCIA 3RVWA 1SP4B 2XU3A 1K3BB 1F2BA 2YJ9A 9PAPA 1Q6KA 1U5IA 1KFXL 2NQGA 2XU5A 5CHTA 2YJ2A 1CJLA 3N4CA 2C0YA 2AUXA 1ZIVA 4MZSA 3V6EA 2E02A 3O0UA 4DMYA 2DJGB 1NPZA 2G7YA 1MHWA 2Y5BA 2XU4A 1NB5A 2E01A 3H6SA 4X6JA 1STFE 2HXZA 2ARYA 2DC7A 2ATOA 3BWKA 2E00A 1CSBB 4AXMA 4CDDB 3P5WA 3AI8A 1FH0A 1U9VA 1BGOA 3C9EA 3OISA 2FQ9A 3IOQA 4P6GA 1BY8A 1HUCB 4XUIA 4I05A 1EWMA 1NB3A 1PIPA 1MS6A 1QDQA 3GCBA 1XKGA 2AIMA 1KHQA 1GCBA 2FTDA 2CB5A 1MDWA 1QMYA 1BQIA 2H7JA 2R9MA 1DF0A 1EWLA 2P86A 4N79A 3BC3A 1A6RA 4YVAA 1VSNA 3F75A 3KW9A 1VJVA 2XU1A 2DJFB 2YJBA 3CBJA 4FK5A 3KX1A 1DEUA 1F2CA 3QT4A 4PP1A 2JQGR 1Y08A 3PDFA 2FO5A 2DZYA 5JH3A 5F02A 3WXGA 3WXFA 4W4UA 4DMXA 1QOLA 4I07A 4RY2A 4AXLA 3P5VA 3IEJA 4Q8HA 3P5UA 1YALA 4PP2E 1GLOA 1S4VA 5EF4A 4N8WA 3PW3A 1NL6A 3ZUAA 2DZZA 3H8BA 3RVXA 5CHVA 3N3KA 1YK7A 6PADA 3H7DA 2YJ8A 2DCCA 4K7CA 1EWOA 1POPA 1ZCMA 3HHAA 1O0EA 3MHSA 1YT7A 1CQDA 2NQAA 3IV2A 2G6DA 3KFQA 2F7DA 1AU3A 1Y4HA 4G54A 4OEMA 3MTNA 2P0RA 3IMAA 1TU6A 2E03A 1EF7A 2IBIA 2DC6A 3KWZA 1MEGA 5EGWA 2FRQA 2AUZA 4YV8A 3M99A 4QRGA 4YYVA 3H8CA 2OULA 1F2AA 1JQPA 1U9XA 2Y6EA 5J94A 1U9QX 3PNRA 5A24A 5CVNB 4YYSA 2DCAA 3HHIA 1MEMA 1YVBA 2GFOA 2AYOA 3K8UA 1NLJA 1CS8A 2O6XA 2VHFA 3KWBX 7PCKA 3D6SA 3PBHA 2AVWA 1ME4A 4BS6A 2FUDA 2R6NA 2YJCA 4YYUA 2JQFR 4W5BA 2G8JA 3IUTA 1PXVA 1PPPA 8PCHA 4PI3A 1AYUA 4P6EA 3ERVA 2DC9A 1PPNA 3USVA 3I06A 4Q8GA 3NHEA 4I04A 3S3RA 1BP4A 2DCBA 1THEA 3IHPA 5CVOB 3HD3A 5JA7A 4CZWA 1PADA 1AYVA 1AU0A 1CB5A 2OZ2A 3OVZA 2AS8A 4YYRA 4FIPA 4FJCA 4MZOA 2HD5A 3E1ZB 2WBFX 2AU1A 3K24A 4ZUXU 4W5CA 3TNXA 4YYQA 4OELA 1X9YA 1PBHA 2B1MA 2PREA 4X6HA 3H89A 2P7UA 3BPFA 3N3GA 3QSDA 3CH2X 2DCDA 4N4ZA 3WXEA 3O1GA 4X6IA 3I3TA 5FPWA 2FT2A 1CV8A 3BPMA 4XR7A 3CBKA 2R9NA 3KKUA
chains in the Genus database with same CATH superfamily
4PADA 2PADA 2B1NA 2PNSA 5PADA 1GMYA 2NQDB 4MSXA 2GHUA 1ITOA 2CIOA 3KSEA 2OP3A 3HWNA 3PT2A 3U8EA 1CTEA 2JRIA 3OQCA 1QXPA 3K9MA 1TL9A 4YYWA 1U9WA 5K16A 3BBAA 2HH5A 2IPPB 1GECE 1NQCA 4D8EA 2AYNA 4R3DA 4QBBA 2ACTA 2BDZA 3BCNA 3LXSA 4KLBA 1AECA 1EWPA 2DC8A 1ICFA 3LFYA 3RVVA 1AU4A 1CPJA 2BTWB 1KFUL 3MHHA 1PPOA 4RF1A 3P5XA 1CVZA 2R9OA 4QH6A 4WURA 5EZSA 3BOWA 1TLOA 2FYEA 2HHNA 1PE6A 4QRVA 4CDCB 3CH3X 3OVXA 4QRXA 4WA6A 3OF9A 1IWDA 3OF8A 3DF0A 2PBHA 2G8EA 1ME3A 1PPDA 2R9CA 4BQVA 2VHSA 1MIRA 1ATKA 2FRAA 3F5VA 3B79A 4BS5A 3S3QA 1SNKA 4BPVA 1YK8A 4HWYA 4RF0A 4D8BA 4CDFB 1F29A 2R9FA 1AYWA 2F1GA 4CDEB 5CVMA 3QJ3A 4BSQA 4MM3B 3V6CA 1AIMA 4BOUA 2BDLA 1AU2A 3MORA 3PHUA 2BTWA 1M6DA 1KXRA 2FE8A 2NQIA 1KHPA 1PCIA 3RVWA 1SP4B 2XU3A 1DKIA 1K3BB 1F2BA 2YJ9A 9PAPA 1Q6KA 4P16A 1U5IA 1KFXL 2NQGA 2XU5A 5CHTA 2YJ2A 1CJLA 3N4CA 2C0YA 2AUXA 5E6JA 1ZIVA 4MZSA 3V6EA 2E02A 3O0UA 4DMYA 4MI7A 2DJGB 3W30A 1NPZA 2G7YA 1MHWA 2Y5BA 4BOSA 2XU4A 1NB5A 2E01A 3H6SA 4X6JA 1STFE 2HXZA 2ARYA 3IFUA 2DC7A 2ATOA 4PT5A 3PRMA 3BWKA 2E00A 1CSBB 4AXMA 4CDDB 3P5WA 3AI8A 1FH0A 4OW0A 3PSEA 1U9VA 1BGOA 3C9EA 2J7QC 3OISA 2FQ9A 3IOQA 4P6GA 1BY8A 1HUCB 4XUIA 4I05A 1EWMA 1YZBA 1NB3A 1PIPA 1MS6A 5JZEA 1QDQA 3GCBA 1XKGA 2AIMA 1KHQA 1GCBA 2FTDA 2CB5A 1MDWA 1QMYA 1BQIA 2H7JA 2R9MA 4REZA 4IUMA 1DF0A 1EWLA 2P86A 4N79A 3BC3A 1A6RA 4YVAA 1VSNA 3F75A 3KW9A 1VJVA 4RNAA 2XU1A 2DJFB 2YJBA 3CBJA 3ZNHA 4FK5A 3KX1A 1DEUA 1F2CA 3QT4A 4PP1A 5KO3A 2JQGR 1Y08A 3PDFA 2FO5A 2DZYA 5JH3A 5F02A 3WXGA 3MP2A 3WXFA 3BY4A 4W4UA 2BU3A 4DMXA 1QOLA 4I07A 4RY2A 4AXLA 3P5VA 3IEJA 4Q8HA 3P5UA 1YALA 4PP2E 2UZJA 1GLOA 1S4VA 4IP3A 4OVZB 5EF4A 4N8WA 3PW3A 1NL6A 3ZUAA 2DZZA 3H8BA 3RNVA 3RVXA 4XZXA 5CHVA 3N3KA 1YK7A 6PADA 3MTVA 3H7DA 2YJ8A 2DCCA 4K7CA 1EWOA 1POPA 1ZCMA 3HHAA 1O0EA 4HXDB 3MHSA 1YT7A 1CQDA 2NQAA 3IV2A 1PVJA 2G6DA 3KFQA 4RKXA 2F7DA 2JTCA 1AU3A 1Y4HA 2Z84A 4G54A 4M0WA 3MTNA 4OEMA 2P0RA 3W31A 4A5UA 3IMAA 1TU6A 2E03A 1EF7A 3PRPA 2IBIA 3BB7A 2DC6A 3KWZA 1MEGA 5EGWA 2FRQA 2AUZA 4ZTBA 4YV8A 3M99A 4QRGA 4YYVA 3H8CA 4BOPA 2OULA 1F2AA 1JQPA 1U9XA 2Y6EA 4OVZA 5J94A 1U9QX 3PNRA 5A24A 5CVNB 4YYSA 2DCAA 3HHIA 1MEMA 1YVBA 2GFOA 3C0RA 2AYOA 3K8UA 4BOZA 1NLJA 1CS8A 3TMPA 2O6XA 2VHFA 3KWBX 7PCKA 3D6SA 5EZQA 3PBHA 2HWKA 2AVWA 1ME4A 4BS6A 4GUAA 2FUDA 2R6NA 2YJCA 4YYUA 2JQFR 4W5BA 2G8JA 3E9SA 3IUTA 1PXVA 1PPPA 3B21A 8PCHA 4PI3A 2DOSA 1AYUA 4P6EA 3ERVA 2DC9A 1PPNA 3USVA 1UKFA 3I06A 4Q8GA 3NHEA 4I04A 3S3RA 4BOQA 1BP4A 2DCBA 1THEA 3IHPA 5CVOB 3HD3A 2AGAA 4CZWA 5JA7A 3PHXA 1PADA 3PHWA 1AYVA 1AU0A 3O65A 1CB5A 2OZ2A 3OVZA 2AS8A 4YYRA 4FIPA 4FJCA 4MZOA 2HD5A 3E1ZB 2WBFX 3MJ5A 2AU1A 3K24A 4ZUXU 4D8IA 4W5CA 3TNXA 2J7QA 4YYQA 4OELA 1X9YA 1PBHA 2B1MA 3TRKA 2PREA 4X6HA 3H89A 2P7UA 3BPFA 3N3GA 3QSDA 3CH2X 2DCDA 4N4ZA 3WXEA 3O1GA 4X6IA 3I3TA 5FPWA 2FT2A 1CV8A 3BPMA 4XR7A 3CBKA 2R9NA 3KKUA
chains in the Genus database with same CATH topology
4PADA 2PADA 2B1NA 2PNSA 5PADA 1GMYA 2NQDB 4MSXA 2GHUA 1ITOA 2CIOA 3KSEA 2OP3A 3HWNA 3U8EA 1CTEA 1QXPA 3K9MA 1TL9A 4YYWA 1U9WA 5K16A 2HH5A 2IPPB 1GECE 1NQCA 2AYNA 4QBBA 2ACTA 1GX3A 2BDZA 3BCNA 3LXSA 4KLBA 1AECA 1EWPA 2DC8A 1ICFA 3LFYA 3RVVA 1AU4A 1CPJA 1KFUL 3MHHA 1PPOA 3D9WA 3P5XA 1CVZA 2R9OA 4QH6A 3BOWA 1TLOA 4GUZA 2FYEA 2HHNA 1PE6A 4QRVA 4CDCB 3CH3X 3OVXA 4QRXA 4WA6A 3LTWA 3OF9A 1IWDA 3OF8A 3DF0A 2PBHA 2G8EA 1ME3A 1PPDA 2R9CA 4BQVA 2VHSA 1MIRA 1ATKA 2FRAA 3F5VA 3B79A 4BS5A 3S3QA 1SNKA 4BPVA 1YK8A 4HWYA 4CDFB 1F29A 4NV7A 2R9FA 1AYWA 2F1GA 4CDEB 5CVMA 3QJ3A 4BSQA 3V6CA 1AIMA 2BDLA 1AU2A 3MORA 1M6DA 1KXRA 2NQIA 1KHPA 1PCIA 3RVWA 1SP4B 2XU3A 1K3BB 4C5PA 1F2BA 2YJ9A 9PAPA 1Q6KA 1U5IA 1KFXL 2NQGA 2XU5A 5CHTA 2YJ2A 4B55A 1CJLA 3N4CA 2C0YA 2AUXA 1ZIVA 4MZSA 3V6EA 2E02A 3O0UA 4DMYA 2DJGB 1NPZA 2G7YA 1MHWA 2Y5BA 4BGFA 2XU4A 1NB5A 2E01A 3H6SA 4X6JA 1STFE 2HXZA 2ARYA 2DC7A 2ATOA 2VFBA 3BWKA 2E00A 1CSBB 4AXMA 4CDDB 3P5WA 3AI8A 1FH0A 1U9VA 1BGOA 2VFCA 3C9EA 3OISA 2FQ9A 3IOQA 4P6GA 1BY8A 1HUCB 4XUIA 4I05A 1EWMA 1NB3A 1PIPA 1MS6A 1QDQA 3GCBA 1XKGA 2AIMA 1KHQA 1GCBA 2FTDA 2CB5A 1MDWA 1QMYA 1BQIA 2H7JA 2R9MA 1DF0A 1EWLA 2P86A 4N79A 3BC3A 1A6RA 4YVAA 1VSNA 3F75A 3KW9A 1VJVA 2XU1A 2DJFB 2YJBA 3CBJA 4FK5A 3KX1A 1DEUA 1F2CA 3QT4A 4PP1A 2JQGR 1Y08A 3PDFA 2FO5A 2DZYA 5JH3A 5F02A 3WXGA 3WXFA 4W4UA 4NV8A 4DMXA 1QOLA 4I07A 4RY2A 4AXLA 3P5VA 3IEJA 4Q8HA 3P5UA 1YALA 4PP2E 1GLOA 1S4VA 5EF4A 4N8WA 3PW3A 1NL6A 3ZUAA 2DZZA 3H8BA 3RVXA 5CHVA 3N3KA 1YK7A 6PADA 3H7DA 2YJ8A 2DCCA 4K7CA 1EWOA 1POPA 1ZCMA 3HHAA 1O0EA 3MHSA 1YT7A 1CQDA 2NQAA 3IV2A 2G6DA 3KFQA 2F7DA 1AU3A 1Y4HA 4G54A 4OEMA 3MTNA 2P0RA 3IMAA 1TU6A 2E03A 1EF7A 2IBIA 2DC6A 3KWZA 1MEGA 5EGWA 2FRQA 2AUZA 4YV8A 3M99A 4QRGA 4YYVA 3H8CA 2OULA 1F2AA 1JQPA 1U9XA 2Y6EA 5J94A 1U9QX 3PNRA 5A24A 5CVNB 4YYSA 2DCAA 3HHIA 1MEMA 1YVBA 2GFOA 2AYOA 3K8UA 1NLJA 1CS8A 2O6XA 2VHFA 3KWBX 7PCKA 3D6SA 3PBHA 2AVWA 1ME4A 4BS6A 2FUDA 2R6NA 2YJCA 4YYUA 2JQFR 4W5BA 2G8JA 3IUTA 1PXVA 1PPPA 2BSZA 8PCHA 4PI3A 1AYUA 4P6EA 3ERVA 2DC9A 1PPNA 3USVA 3I06A 4Q8GA 3NHEA 4I04A 3S3RA 1BP4A 2DCBA 1THEA 3IHPA 5CVOB 3HD3A 5JA7A 4CZWA 1PADA 1AYVA 1AU0A 1CB5A 2OZ2A 1E2TA 3OVZA 2AS8A 4YYRA 4FIPA 4FJCA 4MZOA 2HD5A 3E1ZB 2WBFX 2AU1A 3K24A 4ZUXU 4W5CA 1W6FA 3TNXA 4YYQA 4OELA 1X9YA 1PBHA 2B1MA 2PREA 4X6HA 3H89A 2P7UA 3BPFA 3N3GA 3QSDA 3CH2X 2DCDA 4N4ZA 3WXEA 3O1GA 4X6IA 3I3TA 5FPWA 2FT2A 1CV8A 3BPMA 4XR7A 1W4TA 3CBKA 2R9NA 3KKUA 1W5RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PAD A;  2PAD A;  2B1N A;  2PNS A;  5PAD A;  1GMY A;  2NQD B;  4MSX A;  2GHU A;  1ITO A;  2CIO A;  3KSE A;  2OP3 A;  3HWN A;  3U8E A;  1CTE A;  1QXP A;  3K9M A;  1TL9 A;  4YYW A;  1U9W A;  5K16 A;  2HH5 A;  2IPP B;  1GEC E;  1NQC A;  2AYN A;  4QBB A;  2ACT A;  2BDZ A;  3BCN A;  3LXS A;  4KLB A;  1AEC A;  1EWP A;  2DC8 A;  1ICF A;  3LFY A;  3RVV A;  1AU4 A;  1CPJ A;  1KFU L;  3MHH A;  1PPO A;  3P5X A;  1CVZ A;  2R9O A;  4QH6 A;  3BOW A;  1TLO A;  2FYE A;  2HHN A;  1PE6 A;  4QRV A;  4CDC B;  3CH3 X;  3OVX A;  4QRX A;  4WA6 A;  3OF9 A;  1IWD A;  3OF8 A;  3DF0 A;  2PBH A;  2G8E A;  1ME3 A;  1PPD A;  2R9C A;  4BQV A;  2VHS A;  1MIR A;  1ATK A;  2FRA A;  3F5V A;  3B79 A;  4BS5 A;  3S3Q A;  1SNK A;  4BPV A;  1YK8 A;  4HWY A;  4CDF B;  1F29 A;  2R9F A;  1AYW A;  2F1G A;  4CDE B;  5CVM A;  3QJ3 A;  4BSQ A;  3V6C A;  1AIM A;  2BDL A;  1AU2 A;  3MOR A;  1M6D A;  1KXR A;  2NQI A;  1KHP A;  1PCI A;  3RVW A;  1SP4 B;  2XU3 A;  1K3B B;  1F2B A;  2YJ9 A;  9PAP A;  1Q6K A;  1U5I A;  1KFX L;  2NQG A;  2XU5 A;  5CHT A;  2YJ2 A;  1CJL A;  3N4C A;  2C0Y A;  2AUX A;  1ZIV A;  4MZS A;  3V6E A;  2E02 A;  3O0U A;  4DMY A;  2DJG B;  1NPZ A;  2G7Y A;  1MHW A;  2Y5B A;  2XU4 A;  1NB5 A;  2E01 A;  3H6S A;  4X6J A;  1STF E;  2HXZ A;  2ARY A;  2DC7 A;  2ATO A;  3BWK A;  2E00 A;  1CSB B;  4AXM A;  4CDD B;  3P5W A;  3AI8 A;  1FH0 A;  1U9V A;  1BGO A;  3C9E A;  3OIS A;  2FQ9 A;  3IOQ A;  4P6G A;  1BY8 A;  1HUC B;  4XUI A;  4I05 A;  1EWM A;  1NB3 A;  1PIP A;  1MS6 A;  1QDQ A;  3GCB A;  1XKG A;  2AIM A;  1KHQ A;  1GCB A;  2FTD A;  2CB5 A;  1MDW A;  1QMY A;  1BQI A;  2H7J A;  2R9M A;  1DF0 A;  1EWL A;  2P86 A;  4N79 A;  3BC3 A;  1A6R A;  4YVA A;  1VSN A;  3F75 A;  3KW9 A;  1VJV A;  2XU1 A;  2DJF B;  2YJB A;  3CBJ A;  4FK5 A;  3KX1 A;  1DEU A;  1F2C A;  3QT4 A;  4PP1 A;  2JQG R;  1Y08 A;  3PDF A;  2FO5 A;  2DZY A;  5JH3 A;  5F02 A;  3WXG A;  3WXF A;  4W4U A;  4DMX A;  1QOL A;  4I07 A;  4RY2 A;  4AXL A;  3P5V A;  3IEJ A;  4Q8H A;  3P5U A;  1YAL A;  4PP2 E;  1GLO A;  1S4V A;  5EF4 A;  4N8W A;  3PW3 A;  1NL6 A;  3ZUA A;  2DZZ A;  3H8B A;  3RVX A;  5CHV A;  3N3K A;  1YK7 A;  6PAD A;  3H7D A;  2YJ8 A;  2DCC A;  4K7C A;  1EWO A;  1POP A;  1ZCM A;  3HHA A;  1O0E A;  3MHS A;  1YT7 A;  1CQD A;  2NQA A;  3IV2 A;  2G6D A;  3KFQ A;  2F7D A;  1AU3 A;  1Y4H A;  4G54 A;  4OEM A;  3MTN A;  2P0R A;  3IMA A;  1TU6 A;  2E03 A;  1EF7 A;  2IBI A;  2DC6 A;  3KWZ A;  1MEG A;  5EGW A;  2FRQ A;  2AUZ A;  4YV8 A;  3M99 A;  4QRG A;  4YYV A;  3H8C A;  2OUL A;  1F2A A;  1JQP A;  1U9X A;  2Y6E A;  5J94 A;  1U9Q X;  3PNR A;  5A24 A;  5CVN B;  4YYS A;  2DCA A;  3HHI A;  1MEM A;  1YVB A;  2GFO A;  2AYO A;  3K8U A;  1NLJ A;  1CS8 A;  2O6X A;  2VHF A;  3KWB X;  7PCK A;  3D6S A;  3PBH A;  2AVW A;  1ME4 A;  4BS6 A;  2FUD A;  2R6N A;  2YJC A;  4YYU A;  2JQF R;  4W5B A;  2G8J A;  3IUT A;  1PXV A;  1PPP A;  8PCH A;  4PI3 A;  1AYU A;  4P6E A;  3ERV A;  2DC9 A;  1PPN A;  3USV A;  3I06 A;  4Q8G A;  3NHE A;  4I04 A;  3S3R A;  1BP4 A;  2DCB A;  1THE A;  3IHP A;  5CVO B;  3HD3 A;  5JA7 A;  4CZW A;  1PAD A;  1AYV A;  1AU0 A;  1CB5 A;  2OZ2 A;  3OVZ A;  2AS8 A;  4YYR A;  4FIP A;  4FJC A;  4MZO A;  2HD5 A;  3E1Z B;  2WBF X;  2AU1 A;  3K24 A;  4ZUX U;  4W5C A;  3TNX A;  4YYQ A;  4OEL A;  1X9Y A;  1PBH A;  2B1M A;  2PRE A;  4X6H A;  3H89 A;  2P7U A;  3BPF A;  3N3G A;  3QSD A;  3CH2 X;  2DCD A;  4N4Z A;  3WXE A;  3O1G A;  4X6I A;  3I3T A;  5FPW A;  2FT2 A;  1CV8 A;  3BPM A;  4XR7 A;  3CBK A;  2R9N A;  3KKU A; 
#chains in the Genus database with same CATH topology
 4PAD A;  2PAD A;  2B1N A;  2PNS A;  5PAD A;  1GMY A;  2NQD B;  4MSX A;  2GHU A;  1ITO A;  2CIO A;  3KSE A;  2OP3 A;  3HWN A;  3PT2 A;  3U8E A;  1CTE A;  2JRI A;  3OQC A;  1QXP A;  3K9M A;  1TL9 A;  4YYW A;  1U9W A;  5K16 A;  3BBA A;  2HH5 A;  2IPP B;  1GEC E;  1NQC A;  4D8E A;  2AYN A;  4R3D A;  4QBB A;  2ACT A;  2BDZ A;  3BCN A;  3LXS A;  4KLB A;  1AEC A;  1EWP A;  2DC8 A;  1ICF A;  3LFY A;  3RVV A;  1AU4 A;  1CPJ A;  2BTW B;  1KFU L;  3MHH A;  1PPO A;  4RF1 A;  3P5X A;  1CVZ A;  2R9O A;  4QH6 A;  4WUR A;  5EZS A;  3BOW A;  1TLO A;  2FYE A;  2HHN A;  1PE6 A;  4QRV A;  4CDC B;  3CH3 X;  3OVX A;  4QRX A;  4WA6 A;  3OF9 A;  1IWD A;  3OF8 A;  3DF0 A;  2PBH A;  2G8E A;  1ME3 A;  1PPD A;  2R9C A;  4BQV A;  2VHS A;  1MIR A;  1ATK A;  2FRA A;  3F5V A;  3B79 A;  4BS5 A;  3S3Q A;  1SNK A;  4BPV A;  1YK8 A;  4HWY A;  4RF0 A;  4D8B A;  4CDF B;  1F29 A;  2R9F A;  1AYW A;  2F1G A;  4CDE B;  5CVM A;  3QJ3 A;  4BSQ A;  4MM3 B;  3V6C A;  1AIM A;  4BOU A;  2BDL A;  1AU2 A;  3MOR A;  3PHU A;  2BTW A;  1M6D A;  1KXR A;  2FE8 A;  2NQI A;  1KHP A;  1PCI A;  3RVW A;  1SP4 B;  2XU3 A;  1DKI A;  1K3B B;  1F2B A;  2YJ9 A;  9PAP A;  1Q6K A;  4P16 A;  1U5I A;  1KFX L;  2NQG A;  2XU5 A;  5CHT A;  2YJ2 A;  1CJL A;  3N4C A;  2C0Y A;  2AUX A;  5E6J A;  1ZIV A;  4MZS A;  3V6E A;  2E02 A;  3O0U A;  4DMY A;  4MI7 A;  2DJG B;  3W30 A;  1NPZ A;  2G7Y A;  1MHW A;  2Y5B A;  4BOS A;  2XU4 A;  1NB5 A;  2E01 A;  3H6S A;  4X6J A;  1STF E;  2HXZ A;  2ARY A;  3IFU A;  2DC7 A;  2ATO A;  4PT5 A;  3PRM A;  3BWK A;  2E00 A;  1CSB B;  4AXM A;  4CDD B;  3P5W A;  3AI8 A;  1FH0 A;  4OW0 A;  3PSE A;  1U9V A;  1BGO A;  3C9E A;  2J7Q C;  3OIS A;  2FQ9 A;  3IOQ A;  4P6G A;  1BY8 A;  1HUC B;  4XUI A;  4I05 A;  1EWM A;  1YZB A;  1NB3 A;  1PIP A;  1MS6 A;  5JZE A;  1QDQ A;  3GCB A;  1XKG A;  2AIM A;  1KHQ A;  1GCB A;  2FTD A;  2CB5 A;  1MDW A;  1QMY A;  1BQI A;  2H7J A;  2R9M A;  4REZ A;  4IUM A;  1DF0 A;  1EWL A;  2P86 A;  4N79 A;  3BC3 A;  1A6R A;  4YVA A;  1VSN A;  3F75 A;  3KW9 A;  1VJV A;  4RNA A;  2XU1 A;  2DJF B;  2YJB A;  3CBJ A;  3ZNH A;  4FK5 A;  3KX1 A;  1DEU A;  1F2C A;  3QT4 A;  4PP1 A;  5KO3 A;  2JQG R;  1Y08 A;  3PDF A;  2FO5 A;  2DZY A;  5JH3 A;  5F02 A;  3WXG A;  3MP2 A;  3WXF A;  3BY4 A;  4W4U A;  2BU3 A;  4DMX A;  1QOL A;  4I07 A;  4RY2 A;  4AXL A;  3P5V A;  3IEJ A;  4Q8H A;  3P5U A;  1YAL A;  4PP2 E;  2UZJ A;  1GLO A;  1S4V A;  4IP3 A;  4OVZ B;  5EF4 A;  4N8W A;  3PW3 A;  1NL6 A;  3ZUA A;  2DZZ A;  3H8B A;  3RNV A;  3RVX A;  4XZX A;  5CHV A;  3N3K A;  1YK7 A;  6PAD A;  3MTV A;  3H7D A;  2YJ8 A;  2DCC A;  4K7C A;  1EWO A;  1POP A;  1ZCM A;  3HHA A;  1O0E A;  4HXD B;  3MHS A;  1YT7 A;  1CQD A;  2NQA A;  3IV2 A;  1PVJ A;  2G6D A;  3KFQ A;  4RKX A;  2F7D A;  2JTC A;  1AU3 A;  1Y4H A;  2Z84 A;  4G54 A;  4M0W A;  3MTN A;  4OEM A;  2P0R A;  3W31 A;  4A5U A;  3IMA A;  1TU6 A;  2E03 A;  1EF7 A;  3PRP A;  2IBI A;  3BB7 A;  2DC6 A;  3KWZ A;  1MEG A;  5EGW A;  2FRQ A;  2AUZ A;  4ZTB A;  4YV8 A;  3M99 A;  4QRG A;  4YYV A;  3H8C A;  4BOP A;  2OUL A;  1F2A A;  1JQP A;  1U9X A;  2Y6E A;  4OVZ A;  5J94 A;  1U9Q X;  3PNR A;  5A24 A;  5CVN B;  4YYS A;  2DCA A;  3HHI A;  1MEM A;  1YVB A;  2GFO A;  3C0R A;  2AYO A;  3K8U A;  4BOZ A;  1NLJ A;  1CS8 A;  3TMP A;  2O6X A;  2VHF A;  3KWB X;  7PCK A;  3D6S A;  5EZQ A;  3PBH A;  2HWK A;  2AVW A;  1ME4 A;  4BS6 A;  4GUA A;  2FUD A;  2R6N A;  2YJC A;  4YYU A;  2JQF R;  4W5B A;  2G8J A;  3E9S A;  3IUT A;  1PXV A;  1PPP A;  3B21 A;  8PCH A;  4PI3 A;  2DOS A;  1AYU A;  4P6E A;  3ERV A;  2DC9 A;  1PPN A;  3USV A;  1UKF A;  3I06 A;  4Q8G A;  3NHE A;  4I04 A;  3S3R A;  4BOQ A;  1BP4 A;  2DCB A;  1THE A;  3IHP A;  5CVO B;  3HD3 A;  2AGA A;  4CZW A;  5JA7 A;  3PHX A;  1PAD A;  3PHW A;  1AYV A;  1AU0 A;  3O65 A;  1CB5 A;  2OZ2 A;  3OVZ A;  2AS8 A;  4YYR A;  4FIP A;  4FJC A;  4MZO A;  2HD5 A;  3E1Z B;  2WBF X;  3MJ5 A;  2AU1 A;  3K24 A;  4ZUX U;  4D8I A;  4W5C A;  3TNX A;  2J7Q A;  4YYQ A;  4OEL A;  1X9Y A;  1PBH A;  2B1M A;  3TRK A;  2PRE A;  4X6H A;  3H89 A;  2P7U A;  3BPF A;  3N3G A;  3QSD A;  3CH2 X;  2DCD A;  4N4Z A;  3WXE A;  3O1G A;  4X6I A;  3I3T A;  5FPW A;  2FT2 A;  1CV8 A;  3BPM A;  4XR7 A;  3CBK A;  2R9N A;  3KKU A; 
#chains in the Genus database with same CATH homology
 4PAD A;  2PAD A;  2B1N A;  2PNS A;  5PAD A;  1GMY A;  2NQD B;  4MSX A;  2GHU A;  1ITO A;  2CIO A;  3KSE A;  2OP3 A;  3HWN A;  3U8E A;  1CTE A;  1QXP A;  3K9M A;  1TL9 A;  4YYW A;  1U9W A;  5K16 A;  2HH5 A;  2IPP B;  1GEC E;  1NQC A;  2AYN A;  4QBB A;  2ACT A;  1GX3 A;  2BDZ A;  3BCN A;  3LXS A;  4KLB A;  1AEC A;  1EWP A;  2DC8 A;  1ICF A;  3LFY A;  3RVV A;  1AU4 A;  1CPJ A;  1KFU L;  3MHH A;  1PPO A;  3D9W A;  3P5X A;  1CVZ A;  2R9O A;  4QH6 A;  3BOW A;  1TLO A;  4GUZ A;  2FYE A;  2HHN A;  1PE6 A;  4QRV A;  4CDC B;  3CH3 X;  3OVX A;  4QRX A;  4WA6 A;  3LTW A;  3OF9 A;  1IWD A;  3OF8 A;  3DF0 A;  2PBH A;  2G8E A;  1ME3 A;  1PPD A;  2R9C A;  4BQV A;  2VHS A;  1MIR A;  1ATK A;  2FRA A;  3F5V A;  3B79 A;  4BS5 A;  3S3Q A;  1SNK A;  4BPV A;  1YK8 A;  4HWY A;  4CDF B;  1F29 A;  4NV7 A;  2R9F A;  1AYW A;  2F1G A;  4CDE B;  5CVM A;  3QJ3 A;  4BSQ A;  3V6C A;  1AIM A;  2BDL A;  1AU2 A;  3MOR A;  1M6D A;  1KXR A;  2NQI A;  1KHP A;  1PCI A;  3RVW A;  1SP4 B;  2XU3 A;  1K3B B;  4C5P A;  1F2B A;  2YJ9 A;  9PAP A;  1Q6K A;  1U5I A;  1KFX L;  2NQG A;  2XU5 A;  5CHT A;  2YJ2 A;  4B55 A;  1CJL A;  3N4C A;  2C0Y A;  2AUX A;  1ZIV A;  4MZS A;  3V6E A;  2E02 A;  3O0U A;  4DMY A;  2DJG B;  1NPZ A;  2G7Y A;  1MHW A;  2Y5B A;  4BGF A;  2XU4 A;  1NB5 A;  2E01 A;  3H6S A;  4X6J A;  1STF E;  2HXZ A;  2ARY A;  2DC7 A;  2ATO A;  2VFB A;  3BWK A;  2E00 A;  1CSB B;  4AXM A;  4CDD B;  3P5W A;  3AI8 A;  1FH0 A;  1U9V A;  1BGO A;  2VFC A;  3C9E A;  3OIS A;  2FQ9 A;  3IOQ A;  4P6G A;  1BY8 A;  1HUC B;  4XUI A;  4I05 A;  1EWM A;  1NB3 A;  1PIP A;  1MS6 A;  1QDQ A;  3GCB A;  1XKG A;  2AIM A;  1KHQ A;  1GCB A;  2FTD A;  2CB5 A;  1MDW A;  1QMY A;  1BQI A;  2H7J A;  2R9M A;  1DF0 A;  1EWL A;  2P86 A;  4N79 A;  3BC3 A;  1A6R A;  4YVA A;  1VSN A;  3F75 A;  3KW9 A;  1VJV A;  2XU1 A;  2DJF B;  2YJB A;  3CBJ A;  4FK5 A;  3KX1 A;  1DEU A;  1F2C A;  3QT4 A;  4PP1 A;  2JQG R;  1Y08 A;  3PDF A;  2FO5 A;  2DZY A;  5JH3 A;  5F02 A;  3WXG A;  3WXF A;  4W4U A;  4NV8 A;  4DMX A;  1QOL A;  4I07 A;  4RY2 A;  4AXL A;  3P5V A;  3IEJ A;  4Q8H A;  3P5U A;  1YAL A;  4PP2 E;  1GLO A;  1S4V A;  5EF4 A;  4N8W A;  3PW3 A;  1NL6 A;  3ZUA A;  2DZZ A;  3H8B A;  3RVX A;  5CHV A;  3N3K A;  1YK7 A;  6PAD A;  3H7D A;  2YJ8 A;  2DCC A;  4K7C A;  1EWO A;  1POP A;  1ZCM A;  3HHA A;  1O0E A;  3MHS A;  1YT7 A;  1CQD A;  2NQA A;  3IV2 A;  2G6D A;  3KFQ A;  2F7D A;  1AU3 A;  1Y4H A;  4G54 A;  4OEM A;  3MTN A;  2P0R A;  3IMA A;  1TU6 A;  2E03 A;  1EF7 A;  2IBI A;  2DC6 A;  3KWZ A;  1MEG A;  5EGW A;  2FRQ A;  2AUZ A;  4YV8 A;  3M99 A;  4QRG A;  4YYV A;  3H8C A;  2OUL A;  1F2A A;  1JQP A;  1U9X A;  2Y6E A;  5J94 A;  1U9Q X;  3PNR A;  5A24 A;  5CVN B;  4YYS A;  2DCA A;  3HHI A;  1MEM A;  1YVB A;  2GFO A;  2AYO A;  3K8U A;  1NLJ A;  1CS8 A;  2O6X A;  2VHF A;  3KWB X;  7PCK A;  3D6S A;  3PBH A;  2AVW A;  1ME4 A;  4BS6 A;  2FUD A;  2R6N A;  2YJC A;  4YYU A;  2JQF R;  4W5B A;  2G8J A;  3IUT A;  1PXV A;  1PPP A;  2BSZ A;  8PCH A;  4PI3 A;  1AYU A;  4P6E A;  3ERV A;  2DC9 A;  1PPN A;  3USV A;  3I06 A;  4Q8G A;  3NHE A;  4I04 A;  3S3R A;  1BP4 A;  2DCB A;  1THE A;  3IHP A;  5CVO B;  3HD3 A;  5JA7 A;  4CZW A;  1PAD A;  1AYV A;  1AU0 A;  1CB5 A;  2OZ2 A;  1E2T A;  3OVZ A;  2AS8 A;  4YYR A;  4FIP A;  4FJC A;  4MZO A;  2HD5 A;  3E1Z B;  2WBF X;  2AU1 A;  3K24 A;  4ZUX U;  4W5C A;  1W6F A;  3TNX A;  4YYQ A;  4OEL A;  1X9Y A;  1PBH A;  2B1M A;  2PRE A;  4X6H A;  3H89 A;  2P7U A;  3BPF A;  3N3G A;  3QSD A;  3CH2 X;  2DCD A;  4N4Z A;  3WXE A;  3O1G A;  4X6I A;  3I3T A;  5FPW A;  2FT2 A;  1CV8 A;  3BPM A;  4XR7 A;  1W4T A;  3CBK A;  2R9N A;  3KKU A;  1W5R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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