2XU4A

Cathepsin l with a nitrile inhibitor
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
220
structure length
217
Chain Sequence
APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Systematic Investigation of Halogen Bonding in Protein-Ligand Interactions.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
molecule keywords CATHEPSIN L1
total genus 67
structure length 217
sequence length 220
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2010-10-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2xu4A00
1Y08A 1U5IA 2JQGR 2O6XA 1F29A 2YJBA 1ZCMA 1ATKA 4PP2E 4AXMA 3RVVA 4W4UA 3M99A 2E02A 1U9WA 1CQDA 1XKGA 1SNKA 3BWKA 2CIOA 1YT7A 2FUDA 2G8EA 4MZOA 3HWNA 2E01A 4CDDB 2Y6EA 3V6CA 2VHFA 3BOWA 5CHVA 1PBHA 3PBHA 4CDCB 3KW9A 2P7UA 3H8CA 2DZYA 3U8EA 2PREA 2NQDB 2G8JA 1CSBB 5PADA 1CS8A 4CDFB 3OF9A 1BY8A 3KSEA 1KXRA 2ARYA 3ERVA 1QMYA 3IV2A 2AU1A 2FO5A 3CH3X 3ZUAA 2DCCA 9PAPA 4BS5A 1GLOA 2PNSA 1PPNA 3CBKA 1ME4A 1NPZA 4AXLA 1GMYA 2OZ2A 1PPOA 2B1MA 4X6JA 3IEJA 1PIPA 4PI3A 1X9YA 4PADA 2G7YA 1CVZA 3H89A 4QBBA 1TLOA 4BQVA 1ICFA 5CVNB 2DC8A 1A6RA 4Q8HA 4HWYA 3RVWA 4QRVA 3PW3A 2DC9A 2E00A 3IMAA 2XU4A 2DC7A 1NB3A 1STFE 3P5XA 1KHPA 4ZUXU 2FQ9A 4FJCA 1CJLA 5EGWA 5JH3A 4N79A 2JQFR 1AU4A 4BSQA 4YV8A 3OISA 4K7CA 3CH2X 1K3BB 3OVZA 3O0UA 1MEMA 1AU3A 3K8UA 1MEGA 3D6SA 2NQAA 4YYWA 6PADA 2R6NA 1PXVA 2HD5A 3KKUA 2AYOA 1F2AA 3HHIA 2Y5BA 4QRXA 3P5UA 2YJ8A 1CV8A 2FYEA 1M6DA 3QT4A 2AVWA 8PCHA 5J94A 2OP3A 3F5VA 3PDFA 2B1NA 7PCKA 1AIMA 1BP4A 1QDQA 1QXPA 2FTDA 4YYUA 5JA7A 2BDLA 4XR7A 5F02A 1AYVA 5K16A 3BPFA 5FPWA 4XUIA 3B79A 1KHQA 4I04A 3BCNA 2GFOA 1NLJA 2WBFX 3H7DA 3K24A 2OULA 1AU2A 1YALA 4BPVA 1ZIVA 3DF0A 1CB5A 1O0EA 3S3QA 3K9MA 1F2BA 4P6EA 4OEMA 2HHNA 1EWLA 3WXEA 2R9NA 2DZZA 1F2CA 1YK7A 1GECE 2P0RA 3MORA 1ITOA 4W5CA 3S3RA 2DCDA 1BQIA 3IUTA 4X6IA 4FK5A 3WXGA 3AI8A 1NB5A 2F1GA 4I07A 2DCBA 1MDWA 4YYRA 5EF4A 4YYSA 2AYNA 1AYUA 3P5WA 1DEUA 2E03A 4OELA 1MS6A 3WXFA 2R9FA 1VSNA 3HHAA 2PBHA 4WA6A 3N3GA 4W5BA 4MZSA 4X6HA 2R9CA 1IWDA 2IPPB 3C9EA 2ATOA 1PADA 4KLBA 3QJ3A 3GCBA 3H6SA 1KFUL 2FT2A 3LXSA 2AUXA 2BDZA 3KWBX 2XU1A 2IBIA 2R9OA 3OF8A 3I06A 1SP4B 2YJ9A 3TNXA 2H7JA 1KFXL 4CDEB 2FRAA 4G54A 2HH5A 1U9VA 4DMYA 3USVA 3NHEA 4RY2A 3MHSA 1U9QX 2DC6A 3V6EA 2AS8A 3RVXA 1TL9A 1PPDA 2XU5A 3IOQA 2P86A 3PNRA 4CZWA 1THEA 3MHHA 4FIPA 4Q8GA 1QOLA 1PE6A 3P5VA 3KWZA 3BC3A 3I3TA 1MHWA 1AYWA 1PPPA 1YK8A 3MTNA 1FH0A 1CPJA 4PP1A 3O1GA 4N4ZA 1S4VA 1TU6A 2NQIA 3E1ZB 2DJFB 1AU0A 2PADA 1JQPA 3F75A 3IHPA 3N4CA 3KX1A 2C0YA 3BPMA 5CHTA 2XU3A 1YVBA 4DMXA 1EWPA 1EWMA 1VJVA 4YYQA 1NL6A 2YJCA 2HXZA 5CVMA 2ACTA 4YVAA 1MIRA 4BS6A 2G6DA 2DCAA 1ME3A 1PCIA 4MSXA 2FRQA 1GCBA 2F7DA 3QSDA 4YYVA 1AECA 4P6GA 4QRGA 1Y4HA 4N8WA 2VHSA 2AIMA 1EWOA 3LFYA 2DJGB 2R9MA 2YJ2A 3H8BA 5CVOB 3CBJA 1NQCA 2GHUA 3OVXA 4QH6A 4I05A 1CTEA 1DF0A 1POPA 3N3KA 1HUCB 2AUZA 1Q6KA 1EF7A 1BGOA 1U9XA 3HD3A 2CB5A 5A24A 3KFQA 2NQGA
chains in the Genus database with same CATH superfamily
1Y08A 1U5IA 2JQGR 2J7QA 2O6XA 1F29A 2YJBA 1ZCMA 1ATKA 4PP2E 4AXMA 3RVVA 4W4UA 3M99A 2E02A 1U9WA 1CQDA 1XKGA 1SNKA 3BWKA 2CIOA 1YT7A 2FUDA 2G8EA 4MZOA 3HWNA 2BU3A 2E01A 4CDDB 2Y6EA 3V6CA 2VHFA 3B21A 3BOWA 5CHVA 1PBHA 3PBHA 4IP3A 4CDCB 3KW9A 2P7UA 4OVZA 5KO3A 3H8CA 2DZYA 3PHUA 3U8EA 2PREA 3PHXA 2NQDB 2G8JA 1CSBB 5PADA 1CS8A 4CDFB 3OF9A 1BY8A 3KSEA 1KXRA 2ARYA 3ERVA 1QMYA 3IV2A 2AU1A 2FO5A 3CH3X 3ZUAA 2DCCA 9PAPA 4BS5A 1GLOA 2PNSA 1PPNA 2DOSA 3CBKA 1ME4A 1NPZA 3PT2A 4RNAA 4AXLA 1GMYA 2OZ2A 1PPOA 2B1MA 4D8EA 4X6JA 3PSEA 3IEJA 1PIPA 4PI3A 1X9YA 4PADA 4OVZB 4P16A 2G7YA 1CVZA 5JZEA 3H89A 4QBBA 1TLOA 4MI7A 4BQVA 1ICFA 5CVNB 2DC8A 1A6RA 4Q8HA 4HWYA 3RVWA 4QRVA 2AGAA 4HXDB 3PW3A 2DC9A 2E00A 4D8IA 4ZTBA 3IMAA 2XU4A 2DC7A 3TRKA 1NB3A 1STFE 3P5XA 1KHPA 4ZUXU 2FQ9A 4FJCA 4RKXA 1CJLA 5EGWA 5JH3A 4N79A 2JQFR 2Z84A 1AU4A 2JTCA 3RNVA 4BSQA 4YV8A 3OISA 4K7CA 3CH2X 1K3BB 3OVZA 3O0UA 4REZA 1MEMA 1AU3A 3E9SA 3K8UA 3C0RA 1MEGA 3D6SA 5E6JA 2NQAA 3BY4A 4YYWA 6PADA 2R6NA 1PXVA 2HD5A 3KKUA 2AYOA 1F2AA 3HHIA 2Y5BA 4QRXA 3P5UA 2YJ8A 2UZJA 1CV8A 4RF0A 2FYEA 1M6DA 3QT4A 2AVWA 8PCHA 5J94A 2OP3A 3F5VA 2J7QC 3PDFA 2B1NA 7PCKA 1AIMA 1BP4A 1QDQA 1QXPA 2FTDA 3BB7A 4YYUA 5JA7A 2BDLA 4XR7A 5F02A 1AYVA 5K16A 3BPFA 5FPWA 4XUIA 3B79A 1KHQA 2JRIA 4I04A 3BCNA 2GFOA 1NLJA 2WBFX 3H7DA 3K24A 2OULA 1AU2A 1YALA 4BPVA 1ZIVA 3DF0A 1CB5A 1O0EA 3S3QA 3TMPA 3K9MA 1F2BA 4P6EA 4GUAA 4OEMA 2HHNA 1EWLA 3WXEA 2R9NA 3IFUA 2DZZA 1F2CA 1YK7A 2FE8A 1UKFA 4RF1A 1GECE 2P0RA 3MORA 1ITOA 2BTWB 4W5CA 3S3RA 2DCDA 1BQIA 4PT5A 3IUTA 3MP2A 4X6IA 4FK5A 3WXGA 3AI8A 1NB5A 2F1GA 4I07A 2DCBA 1MDWA 4YYRA 5EF4A 4YYSA 2AYNA 4XZXA 1AYUA 3P5WA 1DEUA 2E03A 4OELA 1MS6A 4IUMA 3WXFA 2R9FA 1VSNA 3HHAA 2PBHA 4WA6A 3N3GA 4W5BA 4MZSA 4X6HA 2R9CA 1IWDA 2IPPB 3C9EA 4MM3B 2ATOA 1PADA 4KLBA 3QJ3A 3W30A 3GCBA 3H6SA 1KFUL 2FT2A 3LXSA 2AUXA 2BDZA 3KWBX 2XU1A 2IBIA 2R9OA 3O65A 3OF8A 4A5UA 3I06A 1SP4B 2YJ9A 3TNXA 2H7JA 3PRMA 1KFXL 4CDEB 2FRAA 4G54A 2HH5A 3MJ5A 1U9VA 3OQCA 4BOZA 4DMYA 3USVA 3NHEA 3MHSA 4RY2A 1U9QX 2DC6A 3V6EA 2AS8A 3RVXA 1TL9A 1PPDA 2XU5A 3IOQA 2HWKA 3W31A 4BOSA 1DKIA 2P86A 5EZQA 3PNRA 4CZWA 1THEA 2BTWA 3MHHA 4FIPA 3MTVA 4Q8GA 1QOLA 1PE6A 3P5VA 3KWZA 3BBAA 3BC3A 3I3TA 4D8BA 4R3DA 1MHWA 1AYWA 1PPPA 1YK8A 3MTNA 1FH0A 4BOQA 1CPJA 4PP1A 3O1GA 4N4ZA 1S4VA 1TU6A 2NQIA 3E1ZB 2DJFB 1AU0A 3ZNHA 2PADA 1JQPA 3F75A 3IHPA 4BOUA 3N4CA 4WURA 4BOPA 3KX1A 2C0YA 3BPMA 5CHTA 2XU3A 3PRPA 1YVBA 4DMXA 1EWPA 1EWMA 1VJVA 4YYQA 1NL6A 2YJCA 2HXZA 5CVMA 2ACTA 4YVAA 1MIRA 4BS6A 2G6DA 2DCAA 1ME3A 1PCIA 4MSXA 2FRQA 1GCBA 2F7DA 3QSDA 4YYVA 1YZBA 1AECA 4P6GA 1PVJA 4QRGA 1Y4HA 4N8WA 5EZSA 2VHSA 2AIMA 1EWOA 3LFYA 2DJGB 2R9MA 2YJ2A 3H8BA 4OW0A 5CVOB 3CBJA 1NQCA 2GHUA 3OVXA 4QH6A 4I05A 1CTEA 1DF0A 1POPA 3N3KA 1HUCB 2AUZA 1Q6KA 1EF7A 4M0WA 1BGOA 1U9XA 3HD3A 2CB5A 5A24A 3KFQA 2NQGA 3PHWA
chains in the Genus database with same CATH topology
1Y08A 1U5IA 2JQGR 2O6XA 1F29A 2YJBA 1ZCMA 1ATKA 4PP2E 4AXMA 3RVVA 4W4UA 3M99A 2E02A 1U9WA 1CQDA 1XKGA 1SNKA 3BWKA 2CIOA 1YT7A 1W4TA 2FUDA 2G8EA 4C5PA 4MZOA 3HWNA 2E01A 4CDDB 2Y6EA 3V6CA 2VHFA 3BOWA 5CHVA 1PBHA 3PBHA 4CDCB 3KW9A 2P7UA 3H8CA 2DZYA 3U8EA 2PREA 2NQDB 2G8JA 1CSBB 5PADA 1CS8A 4CDFB 1GX3A 3OF9A 1BY8A 3KSEA 1KXRA 2ARYA 3ERVA 1QMYA 3IV2A 2AU1A 2FO5A 3CH3X 3ZUAA 2DCCA 9PAPA 4BS5A 1GLOA 2BSZA 2PNSA 1PPNA 3CBKA 1ME4A 1NPZA 4AXLA 1GMYA 2OZ2A 1PPOA 2B1MA 1E2TA 4X6JA 3IEJA 1PIPA 4PI3A 1X9YA 4PADA 2G7YA 1CVZA 3H89A 4QBBA 1TLOA 4BQVA 1ICFA 5CVNB 2DC8A 1A6RA 4Q8HA 4HWYA 3RVWA 4QRVA 3PW3A 2DC9A 2VFBA 2E00A 3IMAA 2XU4A 2DC7A 1NB3A 1STFE 3P5XA 1KHPA 4ZUXU 2FQ9A 4FJCA 1CJLA 5EGWA 5JH3A 4N79A 2JQFR 1AU4A 4BSQA 4YV8A 3OISA 4K7CA 3CH2X 1K3BB 3OVZA 3D9WA 3O0UA 1MEMA 1AU3A 3K8UA 1MEGA 3D6SA 2NQAA 4YYWA 6PADA 2R6NA 1PXVA 2HD5A 3KKUA 2AYOA 1F2AA 3HHIA 2Y5BA 4QRXA 3P5UA 2YJ8A 1CV8A 2FYEA 1M6DA 3QT4A 2AVWA 8PCHA 5J94A 2OP3A 3F5VA 3PDFA 4BGFA 2B1NA 7PCKA 1AIMA 1BP4A 1QDQA 1QXPA 2FTDA 4YYUA 5JA7A 2BDLA 4XR7A 5F02A 1AYVA 5K16A 3BPFA 5FPWA 4XUIA 3B79A 1KHQA 4I04A 2VFCA 3BCNA 2GFOA 1NLJA 2WBFX 3H7DA 3K24A 2OULA 1AU2A 1YALA 4BPVA 1ZIVA 3DF0A 1CB5A 1O0EA 3S3QA 3K9MA 1F2BA 4P6EA 1W5RA 4OEMA 2HHNA 1EWLA 3WXEA 2R9NA 2DZZA 1F2CA 1YK7A 1GECE 2P0RA 3MORA 1ITOA 4W5CA 3S3RA 2DCDA 1BQIA 3IUTA 4X6IA 4FK5A 4GUZA 3WXGA 3AI8A 1NB5A 2F1GA 4I07A 2DCBA 1MDWA 4YYRA 5EF4A 4YYSA 2AYNA 1AYUA 3P5WA 1DEUA 2E03A 4OELA 1MS6A 3WXFA 2R9FA 1VSNA 3HHAA 2PBHA 4WA6A 3N3GA 4W5BA 4MZSA 4X6HA 2R9CA 1IWDA 2IPPB 3C9EA 2ATOA 1PADA 4KLBA 3QJ3A 3GCBA 3H6SA 1KFUL 2FT2A 3LXSA 2AUXA 2BDZA 3KWBX 2XU1A 2IBIA 2R9OA 3LTWA 3OF8A 3I06A 1SP4B 2YJ9A 3TNXA 2H7JA 1KFXL 4CDEB 2FRAA 4G54A 2HH5A 1U9VA 4DMYA 3USVA 3NHEA 4RY2A 3MHSA 1U9QX 2DC6A 3V6EA 1W6FA 2AS8A 3RVXA 1TL9A 1PPDA 2XU5A 3IOQA 2P86A 3PNRA 4CZWA 1THEA 3MHHA 4FIPA 4Q8GA 1QOLA 1PE6A 4NV8A 3P5VA 3KWZA 3BC3A 3I3TA 1MHWA 1AYWA 1PPPA 1YK8A 3MTNA 1FH0A 1CPJA 4PP1A 3O1GA 4N4ZA 1S4VA 1TU6A 2NQIA 3E1ZB 2DJFB 1AU0A 2PADA 1JQPA 3F75A 3IHPA 4B55A 3N4CA 3KX1A 2C0YA 3BPMA 5CHTA 2XU3A 1YVBA 4DMXA 1EWPA 1EWMA 1VJVA 4YYQA 1NL6A 2YJCA 2HXZA 5CVMA 2ACTA 4YVAA 1MIRA 4BS6A 2G6DA 2DCAA 1ME3A 1PCIA 4MSXA 2FRQA 1GCBA 2F7DA 3QSDA 4YYVA 1AECA 4P6GA 4QRGA 1Y4HA 4N8WA 2VHSA 2AIMA 1EWOA 3LFYA 2DJGB 2R9MA 2YJ2A 3H8BA 5CVOB 3CBJA 1NQCA 2GHUA 3OVXA 4QH6A 4I05A 4NV7A 1CTEA 1DF0A 1POPA 3N3KA 1HUCB 2AUZA 1Q6KA 1EF7A 1BGOA 1U9XA 3HD3A 2CB5A 5A24A 3KFQA 2NQGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Y08 A;  1U5I A;  2JQG R;  2O6X A;  1F29 A;  2YJB A;  1ZCM A;  1ATK A;  4PP2 E;  4AXM A;  3RVV A;  4W4U A;  3M99 A;  2E02 A;  1U9W A;  1CQD A;  1XKG A;  1SNK A;  3BWK A;  2CIO A;  1YT7 A;  2FUD A;  2G8E A;  4MZO A;  3HWN A;  2E01 A;  4CDD B;  2Y6E A;  3V6C A;  2VHF A;  3BOW A;  5CHV A;  1PBH A;  3PBH A;  4CDC B;  3KW9 A;  2P7U A;  3H8C A;  2DZY A;  3U8E A;  2PRE A;  2NQD B;  2G8J A;  1CSB B;  5PAD A;  1CS8 A;  4CDF B;  3OF9 A;  1BY8 A;  3KSE A;  1KXR A;  2ARY A;  3ERV A;  1QMY A;  3IV2 A;  2AU1 A;  2FO5 A;  3CH3 X;  3ZUA A;  2DCC A;  9PAP A;  4BS5 A;  1GLO A;  2PNS A;  1PPN A;  3CBK A;  1ME4 A;  1NPZ A;  4AXL A;  1GMY A;  2OZ2 A;  1PPO A;  2B1M A;  4X6J A;  3IEJ A;  1PIP A;  4PI3 A;  1X9Y A;  4PAD A;  2G7Y A;  1CVZ A;  3H89 A;  4QBB A;  1TLO A;  4BQV A;  1ICF A;  5CVN B;  2DC8 A;  1A6R A;  4Q8H A;  4HWY A;  3RVW A;  4QRV A;  3PW3 A;  2DC9 A;  2E00 A;  3IMA A;  2XU4 A;  2DC7 A;  1NB3 A;  1STF E;  3P5X A;  1KHP A;  4ZUX U;  2FQ9 A;  4FJC A;  1CJL A;  5EGW A;  5JH3 A;  4N79 A;  2JQF R;  1AU4 A;  4BSQ A;  4YV8 A;  3OIS A;  4K7C A;  3CH2 X;  1K3B B;  3OVZ A;  3O0U A;  1MEM A;  1AU3 A;  3K8U A;  1MEG A;  3D6S A;  2NQA A;  4YYW A;  6PAD A;  2R6N A;  1PXV A;  2HD5 A;  3KKU A;  2AYO A;  1F2A A;  3HHI A;  2Y5B A;  4QRX A;  3P5U A;  2YJ8 A;  1CV8 A;  2FYE A;  1M6D A;  3QT4 A;  2AVW A;  8PCH A;  5J94 A;  2OP3 A;  3F5V A;  3PDF A;  2B1N A;  7PCK A;  1AIM A;  1BP4 A;  1QDQ A;  1QXP A;  2FTD A;  4YYU A;  5JA7 A;  2BDL A;  4XR7 A;  5F02 A;  1AYV A;  5K16 A;  3BPF A;  5FPW A;  4XUI A;  3B79 A;  1KHQ A;  4I04 A;  3BCN A;  2GFO A;  1NLJ A;  2WBF X;  3H7D A;  3K24 A;  2OUL A;  1AU2 A;  1YAL A;  4BPV A;  1ZIV A;  3DF0 A;  1CB5 A;  1O0E A;  3S3Q A;  3K9M A;  1F2B A;  4P6E A;  4OEM A;  2HHN A;  1EWL A;  3WXE A;  2R9N A;  2DZZ A;  1F2C A;  1YK7 A;  1GEC E;  2P0R A;  3MOR A;  1ITO A;  4W5C A;  3S3R A;  2DCD A;  1BQI A;  3IUT A;  4X6I A;  4FK5 A;  3WXG A;  3AI8 A;  1NB5 A;  2F1G A;  4I07 A;  2DCB A;  1MDW A;  4YYR A;  5EF4 A;  4YYS A;  2AYN A;  1AYU A;  3P5W A;  1DEU A;  2E03 A;  4OEL A;  1MS6 A;  3WXF A;  2R9F A;  1VSN A;  3HHA A;  2PBH A;  4WA6 A;  3N3G A;  4W5B A;  4MZS A;  4X6H A;  2R9C A;  1IWD A;  2IPP B;  3C9E A;  2ATO A;  1PAD A;  4KLB A;  3QJ3 A;  3GCB A;  3H6S A;  1KFU L;  2FT2 A;  3LXS A;  2AUX A;  2BDZ A;  3KWB X;  2XU1 A;  2IBI A;  2R9O A;  3OF8 A;  3I06 A;  1SP4 B;  2YJ9 A;  3TNX A;  2H7J A;  1KFX L;  4CDE B;  2FRA A;  4G54 A;  2HH5 A;  1U9V A;  4DMY A;  3USV A;  3NHE A;  4RY2 A;  3MHS A;  1U9Q X;  2DC6 A;  3V6E A;  2AS8 A;  3RVX A;  1TL9 A;  1PPD A;  2XU5 A;  3IOQ A;  2P86 A;  3PNR A;  4CZW A;  1THE A;  3MHH A;  4FIP A;  4Q8G A;  1QOL A;  1PE6 A;  3P5V A;  3KWZ A;  3BC3 A;  3I3T A;  1MHW A;  1AYW A;  1PPP A;  1YK8 A;  3MTN A;  1FH0 A;  1CPJ A;  4PP1 A;  3O1G A;  4N4Z A;  1S4V A;  1TU6 A;  2NQI A;  3E1Z B;  2DJF B;  1AU0 A;  2PAD A;  1JQP A;  3F75 A;  3IHP A;  3N4C A;  3KX1 A;  2C0Y A;  3BPM A;  5CHT A;  2XU3 A;  1YVB A;  4DMX A;  1EWP A;  1EWM A;  1VJV A;  4YYQ A;  1NL6 A;  2YJC A;  2HXZ A;  5CVM A;  2ACT A;  4YVA A;  1MIR A;  4BS6 A;  2G6D A;  2DCA A;  1ME3 A;  1PCI A;  4MSX A;  2FRQ A;  1GCB A;  2F7D A;  3QSD A;  4YYV A;  1AEC A;  4P6G A;  4QRG A;  1Y4H A;  4N8W A;  2VHS A;  2AIM A;  1EWO A;  3LFY A;  2DJG B;  2R9M A;  2YJ2 A;  3H8B A;  5CVO B;  3CBJ A;  1NQC A;  2GHU A;  3OVX A;  4QH6 A;  4I05 A;  1CTE A;  1DF0 A;  1POP A;  3N3K A;  1HUC B;  2AUZ A;  1Q6K A;  1EF7 A;  1BGO A;  1U9X A;  3HD3 A;  2CB5 A;  5A24 A;  3KFQ A;  2NQG A; 
#chains in the Genus database with same CATH topology
 1Y08 A;  1U5I A;  2JQG R;  2J7Q A;  2O6X A;  1F29 A;  2YJB A;  1ZCM A;  1ATK A;  4PP2 E;  4AXM A;  3RVV A;  4W4U A;  3M99 A;  2E02 A;  1U9W A;  1CQD A;  1XKG A;  1SNK A;  3BWK A;  2CIO A;  1YT7 A;  2FUD A;  2G8E A;  4MZO A;  3HWN A;  2BU3 A;  2E01 A;  4CDD B;  2Y6E A;  3V6C A;  2VHF A;  3B21 A;  3BOW A;  5CHV A;  1PBH A;  3PBH A;  4IP3 A;  4CDC B;  3KW9 A;  2P7U A;  4OVZ A;  5KO3 A;  3H8C A;  2DZY A;  3PHU A;  3U8E A;  2PRE A;  3PHX A;  2NQD B;  2G8J A;  1CSB B;  5PAD A;  1CS8 A;  4CDF B;  3OF9 A;  1BY8 A;  3KSE A;  1KXR A;  2ARY A;  3ERV A;  1QMY A;  3IV2 A;  2AU1 A;  2FO5 A;  3CH3 X;  3ZUA A;  2DCC A;  9PAP A;  4BS5 A;  1GLO A;  2PNS A;  1PPN A;  2DOS A;  3CBK A;  1ME4 A;  1NPZ A;  3PT2 A;  4RNA A;  4AXL A;  1GMY A;  2OZ2 A;  1PPO A;  2B1M A;  4D8E A;  4X6J A;  3PSE A;  3IEJ A;  1PIP A;  4PI3 A;  1X9Y A;  4PAD A;  4OVZ B;  4P16 A;  2G7Y A;  1CVZ A;  5JZE A;  3H89 A;  4QBB A;  1TLO A;  4MI7 A;  4BQV A;  1ICF A;  5CVN B;  2DC8 A;  1A6R A;  4Q8H A;  4HWY A;  3RVW A;  4QRV A;  2AGA A;  4HXD B;  3PW3 A;  2DC9 A;  2E00 A;  4D8I A;  4ZTB A;  3IMA A;  2XU4 A;  2DC7 A;  3TRK A;  1NB3 A;  1STF E;  3P5X A;  1KHP A;  4ZUX U;  2FQ9 A;  4FJC A;  4RKX A;  1CJL A;  5EGW A;  5JH3 A;  4N79 A;  2JQF R;  2Z84 A;  1AU4 A;  2JTC A;  3RNV A;  4BSQ A;  4YV8 A;  3OIS A;  4K7C A;  3CH2 X;  1K3B B;  3OVZ A;  3O0U A;  4REZ A;  1MEM A;  1AU3 A;  3E9S A;  3K8U A;  3C0R A;  1MEG A;  3D6S A;  5E6J A;  2NQA A;  3BY4 A;  4YYW A;  6PAD A;  2R6N A;  1PXV A;  2HD5 A;  3KKU A;  2AYO A;  1F2A A;  3HHI A;  2Y5B A;  4QRX A;  3P5U A;  2YJ8 A;  2UZJ A;  1CV8 A;  4RF0 A;  2FYE A;  1M6D A;  3QT4 A;  2AVW A;  8PCH A;  5J94 A;  2OP3 A;  3F5V A;  2J7Q C;  3PDF A;  2B1N A;  7PCK A;  1AIM A;  1BP4 A;  1QDQ A;  1QXP A;  2FTD A;  3BB7 A;  4YYU A;  5JA7 A;  2BDL A;  4XR7 A;  5F02 A;  1AYV A;  5K16 A;  3BPF A;  5FPW A;  4XUI A;  3B79 A;  1KHQ A;  2JRI A;  4I04 A;  3BCN A;  2GFO A;  1NLJ A;  2WBF X;  3H7D A;  3K24 A;  2OUL A;  1AU2 A;  1YAL A;  4BPV A;  1ZIV A;  3DF0 A;  1CB5 A;  1O0E A;  3S3Q A;  3TMP A;  3K9M A;  1F2B A;  4P6E A;  4GUA A;  4OEM A;  2HHN A;  1EWL A;  3WXE A;  2R9N A;  3IFU A;  2DZZ A;  1F2C A;  1YK7 A;  2FE8 A;  1UKF A;  4RF1 A;  1GEC E;  2P0R A;  3MOR A;  1ITO A;  2BTW B;  4W5C A;  3S3R A;  2DCD A;  1BQI A;  4PT5 A;  3IUT A;  3MP2 A;  4X6I A;  4FK5 A;  3WXG A;  3AI8 A;  1NB5 A;  2F1G A;  4I07 A;  2DCB A;  1MDW A;  4YYR A;  5EF4 A;  4YYS A;  2AYN A;  4XZX A;  1AYU A;  3P5W A;  1DEU A;  2E03 A;  4OEL A;  1MS6 A;  4IUM A;  3WXF A;  2R9F A;  1VSN A;  3HHA A;  2PBH A;  4WA6 A;  3N3G A;  4W5B A;  4MZS A;  4X6H A;  2R9C A;  1IWD A;  2IPP B;  3C9E A;  4MM3 B;  2ATO A;  1PAD A;  4KLB A;  3QJ3 A;  3W30 A;  3GCB A;  3H6S A;  1KFU L;  2FT2 A;  3LXS A;  2AUX A;  2BDZ A;  3KWB X;  2XU1 A;  2IBI A;  2R9O A;  3O65 A;  3OF8 A;  4A5U A;  3I06 A;  1SP4 B;  2YJ9 A;  3TNX A;  2H7J A;  3PRM A;  1KFX L;  4CDE B;  2FRA A;  4G54 A;  2HH5 A;  3MJ5 A;  1U9V A;  3OQC A;  4BOZ A;  4DMY A;  3USV A;  3NHE A;  3MHS A;  4RY2 A;  1U9Q X;  2DC6 A;  3V6E A;  2AS8 A;  3RVX A;  1TL9 A;  1PPD A;  2XU5 A;  3IOQ A;  2HWK A;  3W31 A;  4BOS A;  1DKI A;  2P86 A;  5EZQ A;  3PNR A;  4CZW A;  1THE A;  2BTW A;  3MHH A;  4FIP A;  3MTV A;  4Q8G A;  1QOL A;  1PE6 A;  3P5V A;  3KWZ A;  3BBA A;  3BC3 A;  3I3T A;  4D8B A;  4R3D A;  1MHW A;  1AYW A;  1PPP A;  1YK8 A;  3MTN A;  1FH0 A;  4BOQ A;  1CPJ A;  4PP1 A;  3O1G A;  4N4Z A;  1S4V A;  1TU6 A;  2NQI A;  3E1Z B;  2DJF B;  1AU0 A;  3ZNH A;  2PAD A;  1JQP A;  3F75 A;  3IHP A;  4BOU A;  3N4C A;  4WUR A;  4BOP A;  3KX1 A;  2C0Y A;  3BPM A;  5CHT A;  2XU3 A;  3PRP A;  1YVB A;  4DMX A;  1EWP A;  1EWM A;  1VJV A;  4YYQ A;  1NL6 A;  2YJC A;  2HXZ A;  5CVM A;  2ACT A;  4YVA A;  1MIR A;  4BS6 A;  2G6D A;  2DCA A;  1ME3 A;  1PCI A;  4MSX A;  2FRQ A;  1GCB A;  2F7D A;  3QSD A;  4YYV A;  1YZB A;  1AEC A;  4P6G A;  1PVJ A;  4QRG A;  1Y4H A;  4N8W A;  5EZS A;  2VHS A;  2AIM A;  1EWO A;  3LFY A;  2DJG B;  2R9M A;  2YJ2 A;  3H8B A;  4OW0 A;  5CVO B;  3CBJ A;  1NQC A;  2GHU A;  3OVX A;  4QH6 A;  4I05 A;  1CTE A;  1DF0 A;  1POP A;  3N3K A;  1HUC B;  2AUZ A;  1Q6K A;  1EF7 A;  4M0W A;  1BGO A;  1U9X A;  3HD3 A;  2CB5 A;  5A24 A;  3KFQ A;  2NQG A;  3PHW A; 
#chains in the Genus database with same CATH homology
 1Y08 A;  1U5I A;  2JQG R;  2O6X A;  1F29 A;  2YJB A;  1ZCM A;  1ATK A;  4PP2 E;  4AXM A;  3RVV A;  4W4U A;  3M99 A;  2E02 A;  1U9W A;  1CQD A;  1XKG A;  1SNK A;  3BWK A;  2CIO A;  1YT7 A;  1W4T A;  2FUD A;  2G8E A;  4C5P A;  4MZO A;  3HWN A;  2E01 A;  4CDD B;  2Y6E A;  3V6C A;  2VHF A;  3BOW A;  5CHV A;  1PBH A;  3PBH A;  4CDC B;  3KW9 A;  2P7U A;  3H8C A;  2DZY A;  3U8E A;  2PRE A;  2NQD B;  2G8J A;  1CSB B;  5PAD A;  1CS8 A;  4CDF B;  1GX3 A;  3OF9 A;  1BY8 A;  3KSE A;  1KXR A;  2ARY A;  3ERV A;  1QMY A;  3IV2 A;  2AU1 A;  2FO5 A;  3CH3 X;  3ZUA A;  2DCC A;  9PAP A;  4BS5 A;  1GLO A;  2BSZ A;  2PNS A;  1PPN A;  3CBK A;  1ME4 A;  1NPZ A;  4AXL A;  1GMY A;  2OZ2 A;  1PPO A;  2B1M A;  1E2T A;  4X6J A;  3IEJ A;  1PIP A;  4PI3 A;  1X9Y A;  4PAD A;  2G7Y A;  1CVZ A;  3H89 A;  4QBB A;  1TLO A;  4BQV A;  1ICF A;  5CVN B;  2DC8 A;  1A6R A;  4Q8H A;  4HWY A;  3RVW A;  4QRV A;  3PW3 A;  2DC9 A;  2VFB A;  2E00 A;  3IMA A;  2XU4 A;  2DC7 A;  1NB3 A;  1STF E;  3P5X A;  1KHP A;  4ZUX U;  2FQ9 A;  4FJC A;  1CJL A;  5EGW A;  5JH3 A;  4N79 A;  2JQF R;  1AU4 A;  4BSQ A;  4YV8 A;  3OIS A;  4K7C A;  3CH2 X;  1K3B B;  3OVZ A;  3D9W A;  3O0U A;  1MEM A;  1AU3 A;  3K8U A;  1MEG A;  3D6S A;  2NQA A;  4YYW A;  6PAD A;  2R6N A;  1PXV A;  2HD5 A;  3KKU A;  2AYO A;  1F2A A;  3HHI A;  2Y5B A;  4QRX A;  3P5U A;  2YJ8 A;  1CV8 A;  2FYE A;  1M6D A;  3QT4 A;  2AVW A;  8PCH A;  5J94 A;  2OP3 A;  3F5V A;  3PDF A;  4BGF A;  2B1N A;  7PCK A;  1AIM A;  1BP4 A;  1QDQ A;  1QXP A;  2FTD A;  4YYU A;  5JA7 A;  2BDL A;  4XR7 A;  5F02 A;  1AYV A;  5K16 A;  3BPF A;  5FPW A;  4XUI A;  3B79 A;  1KHQ A;  4I04 A;  2VFC A;  3BCN A;  2GFO A;  1NLJ A;  2WBF X;  3H7D A;  3K24 A;  2OUL A;  1AU2 A;  1YAL A;  4BPV A;  1ZIV A;  3DF0 A;  1CB5 A;  1O0E A;  3S3Q A;  3K9M A;  1F2B A;  4P6E A;  1W5R A;  4OEM A;  2HHN A;  1EWL A;  3WXE A;  2R9N A;  2DZZ A;  1F2C A;  1YK7 A;  1GEC E;  2P0R A;  3MOR A;  1ITO A;  4W5C A;  3S3R A;  2DCD A;  1BQI A;  3IUT A;  4X6I A;  4FK5 A;  4GUZ A;  3WXG A;  3AI8 A;  1NB5 A;  2F1G A;  4I07 A;  2DCB A;  1MDW A;  4YYR A;  5EF4 A;  4YYS A;  2AYN A;  1AYU A;  3P5W A;  1DEU A;  2E03 A;  4OEL A;  1MS6 A;  3WXF A;  2R9F A;  1VSN A;  3HHA A;  2PBH A;  4WA6 A;  3N3G A;  4W5B A;  4MZS A;  4X6H A;  2R9C A;  1IWD A;  2IPP B;  3C9E A;  2ATO A;  1PAD A;  4KLB A;  3QJ3 A;  3GCB A;  3H6S A;  1KFU L;  2FT2 A;  3LXS A;  2AUX A;  2BDZ A;  3KWB X;  2XU1 A;  2IBI A;  2R9O A;  3LTW A;  3OF8 A;  3I06 A;  1SP4 B;  2YJ9 A;  3TNX A;  2H7J A;  1KFX L;  4CDE B;  2FRA A;  4G54 A;  2HH5 A;  1U9V A;  4DMY A;  3USV A;  3NHE A;  4RY2 A;  3MHS A;  1U9Q X;  2DC6 A;  3V6E A;  1W6F A;  2AS8 A;  3RVX A;  1TL9 A;  1PPD A;  2XU5 A;  3IOQ A;  2P86 A;  3PNR A;  4CZW A;  1THE A;  3MHH A;  4FIP A;  4Q8G A;  1QOL A;  1PE6 A;  4NV8 A;  3P5V A;  3KWZ A;  3BC3 A;  3I3T A;  1MHW A;  1AYW A;  1PPP A;  1YK8 A;  3MTN A;  1FH0 A;  1CPJ A;  4PP1 A;  3O1G A;  4N4Z A;  1S4V A;  1TU6 A;  2NQI A;  3E1Z B;  2DJF B;  1AU0 A;  2PAD A;  1JQP A;  3F75 A;  3IHP A;  4B55 A;  3N4C A;  3KX1 A;  2C0Y A;  3BPM A;  5CHT A;  2XU3 A;  1YVB A;  4DMX A;  1EWP A;  1EWM A;  1VJV A;  4YYQ A;  1NL6 A;  2YJC A;  2HXZ A;  5CVM A;  2ACT A;  4YVA A;  1MIR A;  4BS6 A;  2G6D A;  2DCA A;  1ME3 A;  1PCI A;  4MSX A;  2FRQ A;  1GCB A;  2F7D A;  3QSD A;  4YYV A;  1AEC A;  4P6G A;  4QRG A;  1Y4H A;  4N8W A;  2VHS A;  2AIM A;  1EWO A;  3LFY A;  2DJG B;  2R9M A;  2YJ2 A;  3H8B A;  5CVO B;  3CBJ A;  1NQC A;  2GHU A;  3OVX A;  4QH6 A;  4I05 A;  4NV7 A;  1CTE A;  1DF0 A;  1POP A;  3N3K A;  1HUC B;  2AUZ A;  1Q6K A;  1EF7 A;  1BGO A;  1U9X A;  3HD3 A;  2CB5 A;  5A24 A;  3KFQ A;  2NQG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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