1YVBA

The plasmodium falciparum cysteine protease falcipain-2
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
241
structure length
241
Chain Sequence
QMNYEEVIKKYRGEENFDHAAYDWRLHSGVTPVKDQKNCGSCWAFSSIGSVESQYAIRKNKLITLSEQELVDCSFKNYGCNGGLINNAFEDMIELGGICPDGDYPYVSDAPNLCNIDRCTEKYGIKNYLSVPDNKLKEALRFLGPISISVAVSDDFAFYKEGIFDGECGDQLNHAVMLVGFGMKEIVNPLTKKGEKHYYYIIKNSWGQQWGERGFINIETDESGLMRKCGLGTDAFIPLIE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for unique mechanisms of folding and hemoglobin binding by a malarial protease.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Plasmodium falciparum
molecule keywords falcipain 2
total genus 61
structure length 241
sequence length 241
ec nomenclature ec 3.4.22.-:
pdb deposition date 2005-02-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1yvbA00
1KFUL 1AYUA 5EF4A 4X6JA 3KW9A 1ICFA 4I07A 1VJVA 2XU3A 1QOLA 2ARYA 2FUDA 3P5WA 1U9VA 1NB3A 2DC8A 3IHPA 1IWDA 2HHNA 2VHSA 3U8EA 3OF9A 3RVXA 4W4UA 4BS6A 2Y6EA 3AI8A 1VSNA 3LXSA 1FH0A 4PP1A 1AU0A 5J94A 1BQIA 3IOQA 4DMYA 4FIPA 3MHHA 2R9NA 3KKUA 2GFOA 2FT2A 1CSBB 2NQGA 1BY8A 1SNKA 1MEMA 2JQFR 2P0RA 1EF7A 2VHFA 3O1GA 3QSDA 2F1GA 3KX1A 1DF0A 1F2CA 5K16A 1ME4A 3F75A 3CBKA 2G8EA 1PPPA 3N4CA 2YJBA 1YVBA 1ITOA 1CS8A 3P5XA 3USVA 4YYVA 1CVZA 2ACTA 1PCIA 2P86A 2GHUA 3QJ3A 1PE6A 2AVWA 1YK7A 1BGOA 1PIPA 3HHAA 2FTDA 4FK5A 4MSXA 4I05A 1TLOA 5CHVA 2DCCA 2R9OA 3H6SA 4PP2E 1U5IA 3B79A 4P6EA 2G8JA 4BSQA 4YYWA 8PCHA 3F5VA 1ZCMA 4BPVA 2NQIA 3K8UA 3GCBA 5CVOB 3BC3A 1KHPA 2R6NA 3V6CA 3IMAA 3C9EA 4OEMA 1EWPA 1XKGA 1F2AA 2DZZA 5A24A 1M6DA 2JQGR 4AXLA 1SP4B 5CVMA 4DMXA 1PPDA 2E00A 5FPWA 1PBHA 4YV8A 3WXGA 2H7JA 2XU4A 1F29A 3WXFA 4CDDB 3N3KA 1KHQA 4MZOA 1TL9A 4Q8GA 2WBFX 3N3GA 1MEGA 2G7YA 3OISA 2DCDA 2IBIA 1MHWA 5EGWA 2E01A 3KWBX 5F02A 2P7UA 2YJ9A 1U9XA 3O0UA 4I04A 2DC7A 2B1MA 4XUIA 1THEA 2AU1A 5CVNB 3OF8A 1GECE 3MHSA 3PNRA 1ME3A 3KWZA 3ZUAA 4YYSA 1GMYA 3P5VA 2R9MA 2BDZA 2PREA 3HD3A 3RVWA 2YJCA 2CIOA 4CDEB 2B1NA 4QBBA 3BPFA 6PADA 2PBHA 1U9QX 4RY2A 1POPA 2AS8A 1AU4A 1PPOA 1GCBA 2O6XA 2IPPB 2Y5BA 1S4VA 3I3TA 4X6HA 3H8BA 4Q8HA 1QMYA 1NPZA 2PNSA 5JA7A 1EWLA 1DEUA 4XR7A 4N4ZA 4W5CA 2AIMA 2YJ2A 2ATOA 3IV2A 1PXVA 3BPMA 4W5BA 3RVVA 1MIRA 4G54A 4BS5A 1X9YA 2NQDB 2FRQA 1NQCA 3BOWA 3E1ZB 2XU5A 2HD5A 3NHEA 3H8CA 1CQDA 2DZYA 4YYQA 2FO5A 4CZWA 2PADA 3I06A 1CPJA 1AU2A 3KFQA 4AXMA 4P6GA 4YYUA 2FRAA 4PADA 4CDCB 2BDLA 1GLOA 2DCAA 2YJ8A 3H7DA 4PI3A 2E03A 1YALA 2FQ9A 2E02A 4QRXA 3MTNA 3LFYA 2AUZA 1KFXL 3OVXA 2OP3A 1O0EA 2F7DA 4YVAA 4QH6A 2HH5A 3K24A 5JH3A 1NB5A 1ATKA 1BP4A 4K7CA 4ZUXU 1AIMA 3BCNA 2G6DA 1Y08A 2NQAA 1CB5A 3PBHA 2OZ2A 1NLJA 2OULA 1QDQA 3KSEA 1KXRA 4QRVA 3ERVA 1NL6A 1Q6KA 1K3BB 3HHIA 4X6IA 4YYRA 3HWNA 3CH2X 1EWMA 2AYOA 4MZSA 3CBJA 4FJCA 2AYNA 4N8WA 1U9WA 2CB5A 1A6RA 1PADA 3WXEA 1QXPA 1STFE 2R9CA 3OVZA 3S3RA 3V6EA 5CHTA 3TNXA 1MDWA 4QRGA 3P5UA 4N79A 3PW3A 2DCBA 2HXZA 7PCKA 1CTEA 3S3QA 2C0YA 3BWKA 2DC6A 1YK8A 3QT4A 1AECA 1MS6A 2XU1A 4HWYA 1F2BA 4WA6A 1JQPA 4CDFB 1PPNA 2FYEA 1YT7A 1EWOA 2DJGB 4OELA 1CV8A 1CJLA 1AYVA 1Y4HA 4BQVA 3PDFA 3K9MA 2DC9A 1TU6A 5PADA 1AYWA 3H89A 2AUXA 3D6SA 3M99A 9PAPA 2DJFB 3DF0A 1ZIVA 4KLBA 3IEJA 2R9FA 3MORA 1AU3A 1HUCB 3IUTA 3CH3X
chains in the Genus database with same CATH superfamily
1KFUL 1AYUA 5EF4A 4X6JA 3KW9A 1ICFA 4I07A 1VJVA 2XU3A 1QOLA 2ARYA 2FUDA 3P5WA 1U9VA 2JTCA 1NB3A 2DC8A 3IHPA 1IWDA 2HHNA 2VHSA 3PSEA 3MTVA 3TRKA 3U8EA 3OF9A 3RVXA 4W4UA 5KO3A 4BS6A 2Y6EA 3AI8A 1VSNA 4HXDB 3LXSA 1FH0A 4PP1A 1AU0A 5J94A 1BQIA 3IOQA 4DMYA 4FIPA 3MHHA 2R9NA 3KKUA 2GFOA 2FT2A 1CSBB 2NQGA 2HWKA 1BY8A 3C0RA 1SNKA 4RF1A 4BOSA 1MEMA 2JQFR 2UZJA 2P0RA 1EF7A 2VHFA 3O1GA 3QSDA 2F1GA 3RNVA 3KX1A 2BU3A 1DF0A 4WURA 1F2CA 5K16A 1ME4A 3F75A 3CBKA 3W30A 2G8EA 1DKIA 3ZNHA 1PPPA 3N4CA 2YJBA 1YVBA 1ITOA 1CS8A 3P5XA 3USVA 4YYVA 1CVZA 2ACTA 4BOUA 1PCIA 2P86A 2GHUA 3PHXA 3PHUA 3QJ3A 4D8BA 1PE6A 2AVWA 1YK7A 1BGOA 1PIPA 3HHAA 2FTDA 4FK5A 4M0WA 4MSXA 3BBAA 4I05A 2FE8A 1TLOA 5CHVA 2DCCA 2R9OA 1YZBA 3H6SA 4PP2E 1U5IA 3B79A 4P6EA 2G8JA 4BSQA 4YYWA 8PCHA 3F5VA 4PT5A 1ZCMA 4BPVA 2NQIA 3K8UA 3GCBA 5CVOB 3PHWA 3BC3A 5JZEA 1KHPA 2R6NA 3V6CA 3PRMA 3IMAA 3C9EA 3MJ5A 4OEMA 1EWPA 1XKGA 1F2AA 3MP2A 3OQCA 2DZZA 5A24A 1M6DA 2JQGR 4AXLA 1SP4B 5CVMA 4DMXA 1PPDA 2E00A 4ZTBA 5FPWA 1PBHA 4YV8A 3WXGA 2H7JA 2XU4A 1F29A 3WXFA 4CDDB 3N3KA 4OVZA 1KHQA 4MZOA 1TL9A 4Q8GA 2WBFX 3N3GA 1MEGA 2G7YA 3OISA 2DCDA 2IBIA 1MHWA 5EGWA 2E01A 3KWBX 5F02A 2P7UA 2YJ9A 1U9XA 3O0UA 4I04A 2DC7A 2B1MA 4XUIA 1THEA 2AU1A 3BB7A 5CVNB 3OF8A 1GECE 3W31A 4MI7A 3MHSA 3PNRA 1ME3A 3KWZA 3ZUAA 4MM3B 4YYSA 5EZSA 1GMYA 3P5VA 4BOPA 2R9MA 4OVZB 2BDZA 2PREA 3HD3A 4IUMA 3RVWA 2YJCA 2CIOA 4CDEB 2B1NA 4QBBA 3BPFA 6PADA 2PBHA 1U9QX 4RY2A 1POPA 2AS8A 1AU4A 1PPOA 1GCBA 2O6XA 2IPPB 2Y5BA 1S4VA 3I3TA 4X6HA 3H8BA 4Q8HA 1UKFA 1QMYA 1NPZA 4BOZA 5EZQA 2PNSA 5JA7A 1EWLA 1DEUA 4XR7A 4N4ZA 4W5CA 2DOSA 2AIMA 2YJ2A 3BY4A 2ATOA 3IV2A 4RNAA 1PXVA 3BPMA 4W5BA 3RVVA 3E9SA 1MIRA 4G54A 4BS5A 1X9YA 2NQDB 2FRQA 1NQCA 3BOWA 3E1ZB 4D8IA 2XU5A 2HD5A 3NHEA 3H8CA 1CQDA 2DZYA 4YYQA 2FO5A 4D8EA 4CZWA 2PADA 3I06A 1CPJA 4BOQA 1AU2A 3KFQA 3PT2A 4AXMA 4REZA 4P6GA 1PVJA 4YYUA 2FRAA 4PADA 4CDCB 2BDLA 1GLOA 2DCAA 2YJ8A 3H7DA 4PI3A 2E03A 1YALA 2FQ9A 5E6JA 2E02A 4QRXA 3MTNA 3LFYA 2AUZA 1KFXL 3OVXA 2OP3A 1O0EA 2F7DA 4YVAA 4QH6A 2BTWB 2HH5A 3K24A 5JH3A 4OW0A 1NB5A 1ATKA 1BP4A 4R3DA 4K7CA 4ZUXU 1AIMA 3BCNA 2G6DA 1Y08A 4IP3A 2NQAA 3PRPA 1CB5A 3PBHA 2OZ2A 1NLJA 2OULA 4P16A 3B21A 1QDQA 3KSEA 1KXRA 4QRVA 3ERVA 1NL6A 1Q6KA 1K3BB 3HHIA 4X6IA 4RKXA 4YYRA 3HWNA 3CH2X 1EWMA 2JRIA 2AYOA 4MZSA 3CBJA 4FJCA 2AYNA 4N8WA 1U9WA 2CB5A 1A6RA 1PADA 2J7QA 3WXEA 1QXPA 1STFE 2R9CA 2J7QC 3OVZA 3S3RA 3V6EA 5CHTA 3TNXA 1MDWA 4GUAA 4QRGA 3P5UA 4N79A 3O65A 3PW3A 2DCBA 2HXZA 7PCKA 1CTEA 3S3QA 2C0YA 3BWKA 2DC6A 1YK8A 3QT4A 1AECA 1MS6A 2XU1A 4HWYA 1F2BA 4WA6A 1JQPA 4CDFB 1PPNA 2FYEA 1YT7A 1EWOA 2Z84A 2DJGB 3TMPA 4OELA 1CV8A 1CJLA 1AYVA 1Y4HA 4BQVA 2BTWA 3PDFA 3K9MA 2DC9A 1TU6A 5PADA 4XZXA 1AYWA 3H89A 2AUXA 4RF0A 3D6SA 3M99A 9PAPA 2DJFB 3DF0A 1ZIVA 4KLBA 2AGAA 4A5UA 3IEJA 2R9FA 3MORA 1AU3A 3IFUA 1HUCB 3IUTA 3CH3X
chains in the Genus database with same CATH topology
1KFUL 4GUZA 1AYUA 5EF4A 4X6JA 3KW9A 1ICFA 4I07A 1VJVA 2XU3A 1QOLA 2ARYA 2FUDA 3P5WA 1U9VA 1NB3A 2DC8A 3IHPA 1IWDA 2HHNA 2VHSA 3U8EA 3OF9A 3RVXA 4W4UA 4BS6A 2Y6EA 3AI8A 1VSNA 3LXSA 1FH0A 4PP1A 1AU0A 5J94A 1BQIA 3IOQA 4DMYA 4FIPA 3MHHA 2R9NA 3KKUA 2GFOA 2FT2A 1CSBB 2NQGA 1BY8A 1SNKA 1MEMA 2JQFR 2P0RA 1EF7A 2VHFA 3O1GA 3QSDA 2F1GA 3KX1A 1DF0A 1F2CA 5K16A 1ME4A 3F75A 3CBKA 2G8EA 1PPPA 3N4CA 2YJBA 1YVBA 1ITOA 1CS8A 3P5XA 3USVA 4YYVA 1CVZA 2ACTA 1PCIA 2P86A 2GHUA 3QJ3A 1PE6A 2AVWA 1YK7A 1BGOA 1PIPA 3HHAA 2FTDA 4FK5A 3D9WA 4MSXA 4I05A 3LTWA 1TLOA 5CHVA 2DCCA 2R9OA 3H6SA 4PP2E 2VFBA 1U5IA 3B79A 4P6EA 2G8JA 4BSQA 4YYWA 8PCHA 3F5VA 1ZCMA 4BPVA 2NQIA 3K8UA 3GCBA 5CVOB 3BC3A 1KHPA 2R6NA 3V6CA 3IMAA 3C9EA 4OEMA 1EWPA 1XKGA 1F2AA 2DZZA 5A24A 1M6DA 2JQGR 4AXLA 1SP4B 5CVMA 4DMXA 1PPDA 2E00A 5FPWA 1PBHA 4YV8A 3WXGA 2H7JA 2XU4A 1F29A 3WXFA 4CDDB 3N3KA 1KHQA 4MZOA 1TL9A 4Q8GA 2WBFX 3N3GA 1W5RA 1MEGA 2G7YA 3OISA 2DCDA 2IBIA 1MHWA 5EGWA 2E01A 3KWBX 5F02A 2P7UA 2YJ9A 1W6FA 1U9XA 3O0UA 4I04A 2DC7A 2B1MA 4XUIA 1THEA 2AU1A 5CVNB 3OF8A 1GECE 3MHSA 3PNRA 1ME3A 3KWZA 3ZUAA 4YYSA 1GMYA 3P5VA 2R9MA 2BDZA 2PREA 3HD3A 3RVWA 2YJCA 2CIOA 4CDEB 2B1NA 4QBBA 3BPFA 6PADA 2PBHA 1U9QX 4RY2A 1POPA 2AS8A 1AU4A 1PPOA 1GCBA 2O6XA 2IPPB 2Y5BA 1S4VA 3I3TA 4X6HA 3H8BA 4C5PA 4Q8HA 1QMYA 1NPZA 1E2TA 2PNSA 5JA7A 1EWLA 1DEUA 4XR7A 4N4ZA 4W5CA 2AIMA 2YJ2A 2ATOA 3IV2A 1W4TA 1PXVA 3BPMA 4W5BA 3RVVA 1MIRA 4G54A 4BS5A 1X9YA 2NQDB 2FRQA 1NQCA 3BOWA 3E1ZB 2XU5A 2HD5A 3NHEA 3H8CA 1CQDA 2DZYA 4YYQA 2FO5A 4CZWA 2PADA 3I06A 1CPJA 1AU2A 3KFQA 4AXMA 2VFCA 4P6GA 4YYUA 2FRAA 4PADA 4CDCB 2BDLA 1GLOA 2DCAA 2YJ8A 3H7DA 4PI3A 2E03A 1YALA 2FQ9A 2E02A 4QRXA 3MTNA 3LFYA 2AUZA 1KFXL 3OVXA 2OP3A 1O0EA 2F7DA 4YVAA 4QH6A 2HH5A 3K24A 5JH3A 1NB5A 1ATKA 1BP4A 4K7CA 4ZUXU 1AIMA 3BCNA 2G6DA 4NV8A 1Y08A 2NQAA 1CB5A 3PBHA 2OZ2A 1NLJA 2OULA 1QDQA 3KSEA 1KXRA 4QRVA 3ERVA 1NL6A 1Q6KA 1K3BB 3HHIA 4X6IA 4YYRA 3HWNA 3CH2X 1EWMA 2AYOA 4MZSA 4NV7A 3CBJA 4FJCA 2AYNA 4N8WA 1U9WA 2CB5A 1A6RA 1PADA 3WXEA 1QXPA 1STFE 2R9CA 3OVZA 3S3RA 3V6EA 5CHTA 3TNXA 1MDWA 4QRGA 3P5UA 4N79A 3PW3A 2DCBA 2HXZA 7PCKA 1CTEA 3S3QA 4B55A 2C0YA 3BWKA 2DC6A 1YK8A 3QT4A 1AECA 1MS6A 2XU1A 4HWYA 1F2BA 4WA6A 1JQPA 4CDFB 1PPNA 2FYEA 1YT7A 1EWOA 2DJGB 4OELA 1CV8A 1CJLA 1AYVA 1Y4HA 4BQVA 3PDFA 3K9MA 2DC9A 1GX3A 1TU6A 5PADA 1AYWA 3H89A 2AUXA 3D6SA 3M99A 9PAPA 2DJFB 3DF0A 1ZIVA 4KLBA 2BSZA 3IEJA 2R9FA 3MORA 1AU3A 1HUCB 3IUTA 4BGFA 3CH3X
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KFU L;  1AYU A;  5EF4 A;  4X6J A;  3KW9 A;  1ICF A;  4I07 A;  1VJV A;  2XU3 A;  1QOL A;  2ARY A;  2FUD A;  3P5W A;  1U9V A;  1NB3 A;  2DC8 A;  3IHP A;  1IWD A;  2HHN A;  2VHS A;  3U8E A;  3OF9 A;  3RVX A;  4W4U A;  4BS6 A;  2Y6E A;  3AI8 A;  1VSN A;  3LXS A;  1FH0 A;  4PP1 A;  1AU0 A;  5J94 A;  1BQI A;  3IOQ A;  4DMY A;  4FIP A;  3MHH A;  2R9N A;  3KKU A;  2GFO A;  2FT2 A;  1CSB B;  2NQG A;  1BY8 A;  1SNK A;  1MEM A;  2JQF R;  2P0R A;  1EF7 A;  2VHF A;  3O1G A;  3QSD A;  2F1G A;  3KX1 A;  1DF0 A;  1F2C A;  5K16 A;  1ME4 A;  3F75 A;  3CBK A;  2G8E A;  1PPP A;  3N4C A;  2YJB A;  1YVB A;  1ITO A;  1CS8 A;  3P5X A;  3USV A;  4YYV A;  1CVZ A;  2ACT A;  1PCI A;  2P86 A;  2GHU A;  3QJ3 A;  1PE6 A;  2AVW A;  1YK7 A;  1BGO A;  1PIP A;  3HHA A;  2FTD A;  4FK5 A;  4MSX A;  4I05 A;  1TLO A;  5CHV A;  2DCC A;  2R9O A;  3H6S A;  4PP2 E;  1U5I A;  3B79 A;  4P6E A;  2G8J A;  4BSQ A;  4YYW A;  8PCH A;  3F5V A;  1ZCM A;  4BPV A;  2NQI A;  3K8U A;  3GCB A;  5CVO B;  3BC3 A;  1KHP A;  2R6N A;  3V6C A;  3IMA A;  3C9E A;  4OEM A;  1EWP A;  1XKG A;  1F2A A;  2DZZ A;  5A24 A;  1M6D A;  2JQG R;  4AXL A;  1SP4 B;  5CVM A;  4DMX A;  1PPD A;  2E00 A;  5FPW A;  1PBH A;  4YV8 A;  3WXG A;  2H7J A;  2XU4 A;  1F29 A;  3WXF A;  4CDD B;  3N3K A;  1KHQ A;  4MZO A;  1TL9 A;  4Q8G A;  2WBF X;  3N3G A;  1MEG A;  2G7Y A;  3OIS A;  2DCD A;  2IBI A;  1MHW A;  5EGW A;  2E01 A;  3KWB X;  5F02 A;  2P7U A;  2YJ9 A;  1U9X A;  3O0U A;  4I04 A;  2DC7 A;  2B1M A;  4XUI A;  1THE A;  2AU1 A;  5CVN B;  3OF8 A;  1GEC E;  3MHS A;  3PNR A;  1ME3 A;  3KWZ A;  3ZUA A;  4YYS A;  1GMY A;  3P5V A;  2R9M A;  2BDZ A;  2PRE A;  3HD3 A;  3RVW A;  2YJC A;  2CIO A;  4CDE B;  2B1N A;  4QBB A;  3BPF A;  6PAD A;  2PBH A;  1U9Q X;  4RY2 A;  1POP A;  2AS8 A;  1AU4 A;  1PPO A;  1GCB A;  2O6X A;  2IPP B;  2Y5B A;  1S4V A;  3I3T A;  4X6H A;  3H8B A;  4Q8H A;  1QMY A;  1NPZ A;  2PNS A;  5JA7 A;  1EWL A;  1DEU A;  4XR7 A;  4N4Z A;  4W5C A;  2AIM A;  2YJ2 A;  2ATO A;  3IV2 A;  1PXV A;  3BPM A;  4W5B A;  3RVV A;  1MIR A;  4G54 A;  4BS5 A;  1X9Y A;  2NQD B;  2FRQ A;  1NQC A;  3BOW A;  3E1Z B;  2XU5 A;  2HD5 A;  3NHE A;  3H8C A;  1CQD A;  2DZY A;  4YYQ A;  2FO5 A;  4CZW A;  2PAD A;  3I06 A;  1CPJ A;  1AU2 A;  3KFQ A;  4AXM A;  4P6G A;  4YYU A;  2FRA A;  4PAD A;  4CDC B;  2BDL A;  1GLO A;  2DCA A;  2YJ8 A;  3H7D A;  4PI3 A;  2E03 A;  1YAL A;  2FQ9 A;  2E02 A;  4QRX A;  3MTN A;  3LFY A;  2AUZ A;  1KFX L;  3OVX A;  2OP3 A;  1O0E A;  2F7D A;  4YVA A;  4QH6 A;  2HH5 A;  3K24 A;  5JH3 A;  1NB5 A;  1ATK A;  1BP4 A;  4K7C A;  4ZUX U;  1AIM A;  3BCN A;  2G6D A;  1Y08 A;  2NQA A;  1CB5 A;  3PBH A;  2OZ2 A;  1NLJ A;  2OUL A;  1QDQ A;  3KSE A;  1KXR A;  4QRV A;  3ERV A;  1NL6 A;  1Q6K A;  1K3B B;  3HHI A;  4X6I A;  4YYR A;  3HWN A;  3CH2 X;  1EWM A;  2AYO A;  4MZS A;  3CBJ A;  4FJC A;  2AYN A;  4N8W A;  1U9W A;  2CB5 A;  1A6R A;  1PAD A;  3WXE A;  1QXP A;  1STF E;  2R9C A;  3OVZ A;  3S3R A;  3V6E A;  5CHT A;  3TNX A;  1MDW A;  4QRG A;  3P5U A;  4N79 A;  3PW3 A;  2DCB A;  2HXZ A;  7PCK A;  1CTE A;  3S3Q A;  2C0Y A;  3BWK A;  2DC6 A;  1YK8 A;  3QT4 A;  1AEC A;  1MS6 A;  2XU1 A;  4HWY A;  1F2B A;  4WA6 A;  1JQP A;  4CDF B;  1PPN A;  2FYE A;  1YT7 A;  1EWO A;  2DJG B;  4OEL A;  1CV8 A;  1CJL A;  1AYV A;  1Y4H A;  4BQV A;  3PDF A;  3K9M A;  2DC9 A;  1TU6 A;  5PAD A;  1AYW A;  3H89 A;  2AUX A;  3D6S A;  3M99 A;  9PAP A;  2DJF B;  3DF0 A;  1ZIV A;  4KLB A;  3IEJ A;  2R9F A;  3MOR A;  1AU3 A;  1HUC B;  3IUT A;  3CH3 X; 
#chains in the Genus database with same CATH topology
 1KFU L;  1AYU A;  5EF4 A;  4X6J A;  3KW9 A;  1ICF A;  4I07 A;  1VJV A;  2XU3 A;  1QOL A;  2ARY A;  2FUD A;  3P5W A;  1U9V A;  2JTC A;  1NB3 A;  2DC8 A;  3IHP A;  1IWD A;  2HHN A;  2VHS A;  3PSE A;  3MTV A;  3TRK A;  3U8E A;  3OF9 A;  3RVX A;  4W4U A;  5KO3 A;  4BS6 A;  2Y6E A;  3AI8 A;  1VSN A;  4HXD B;  3LXS A;  1FH0 A;  4PP1 A;  1AU0 A;  5J94 A;  1BQI A;  3IOQ A;  4DMY A;  4FIP A;  3MHH A;  2R9N A;  3KKU A;  2GFO A;  2FT2 A;  1CSB B;  2NQG A;  2HWK A;  1BY8 A;  3C0R A;  1SNK A;  4RF1 A;  4BOS A;  1MEM A;  2JQF R;  2UZJ A;  2P0R A;  1EF7 A;  2VHF A;  3O1G A;  3QSD A;  2F1G A;  3RNV A;  3KX1 A;  2BU3 A;  1DF0 A;  4WUR A;  1F2C A;  5K16 A;  1ME4 A;  3F75 A;  3CBK A;  3W30 A;  2G8E A;  1DKI A;  3ZNH A;  1PPP A;  3N4C A;  2YJB A;  1YVB A;  1ITO A;  1CS8 A;  3P5X A;  3USV A;  4YYV A;  1CVZ A;  2ACT A;  4BOU A;  1PCI A;  2P86 A;  2GHU A;  3PHX A;  3PHU A;  3QJ3 A;  4D8B A;  1PE6 A;  2AVW A;  1YK7 A;  1BGO A;  1PIP A;  3HHA A;  2FTD A;  4FK5 A;  4M0W A;  4MSX A;  3BBA A;  4I05 A;  2FE8 A;  1TLO A;  5CHV A;  2DCC A;  2R9O A;  1YZB A;  3H6S A;  4PP2 E;  1U5I A;  3B79 A;  4P6E A;  2G8J A;  4BSQ A;  4YYW A;  8PCH A;  3F5V A;  4PT5 A;  1ZCM A;  4BPV A;  2NQI A;  3K8U A;  3GCB A;  5CVO B;  3PHW A;  3BC3 A;  5JZE A;  1KHP A;  2R6N A;  3V6C A;  3PRM A;  3IMA A;  3C9E A;  3MJ5 A;  4OEM A;  1EWP A;  1XKG A;  1F2A A;  3MP2 A;  3OQC A;  2DZZ A;  5A24 A;  1M6D A;  2JQG R;  4AXL A;  1SP4 B;  5CVM A;  4DMX A;  1PPD A;  2E00 A;  4ZTB A;  5FPW A;  1PBH A;  4YV8 A;  3WXG A;  2H7J A;  2XU4 A;  1F29 A;  3WXF A;  4CDD B;  3N3K A;  4OVZ A;  1KHQ A;  4MZO A;  1TL9 A;  4Q8G A;  2WBF X;  3N3G A;  1MEG A;  2G7Y A;  3OIS A;  2DCD A;  2IBI A;  1MHW A;  5EGW A;  2E01 A;  3KWB X;  5F02 A;  2P7U A;  2YJ9 A;  1U9X A;  3O0U A;  4I04 A;  2DC7 A;  2B1M A;  4XUI A;  1THE A;  2AU1 A;  3BB7 A;  5CVN B;  3OF8 A;  1GEC E;  3W31 A;  4MI7 A;  3MHS A;  3PNR A;  1ME3 A;  3KWZ A;  3ZUA A;  4MM3 B;  4YYS A;  5EZS A;  1GMY A;  3P5V A;  4BOP A;  2R9M A;  4OVZ B;  2BDZ A;  2PRE A;  3HD3 A;  4IUM A;  3RVW A;  2YJC A;  2CIO A;  4CDE B;  2B1N A;  4QBB A;  3BPF A;  6PAD A;  2PBH A;  1U9Q X;  4RY2 A;  1POP A;  2AS8 A;  1AU4 A;  1PPO A;  1GCB A;  2O6X A;  2IPP B;  2Y5B A;  1S4V A;  3I3T A;  4X6H A;  3H8B A;  4Q8H A;  1UKF A;  1QMY A;  1NPZ A;  4BOZ A;  5EZQ A;  2PNS A;  5JA7 A;  1EWL A;  1DEU A;  4XR7 A;  4N4Z A;  4W5C A;  2DOS A;  2AIM A;  2YJ2 A;  3BY4 A;  2ATO A;  3IV2 A;  4RNA A;  1PXV A;  3BPM A;  4W5B A;  3RVV A;  3E9S A;  1MIR A;  4G54 A;  4BS5 A;  1X9Y A;  2NQD B;  2FRQ A;  1NQC A;  3BOW A;  3E1Z B;  4D8I A;  2XU5 A;  2HD5 A;  3NHE A;  3H8C A;  1CQD A;  2DZY A;  4YYQ A;  2FO5 A;  4D8E A;  4CZW A;  2PAD A;  3I06 A;  1CPJ A;  4BOQ A;  1AU2 A;  3KFQ A;  3PT2 A;  4AXM A;  4REZ A;  4P6G A;  1PVJ A;  4YYU A;  2FRA A;  4PAD A;  4CDC B;  2BDL A;  1GLO A;  2DCA A;  2YJ8 A;  3H7D A;  4PI3 A;  2E03 A;  1YAL A;  2FQ9 A;  5E6J A;  2E02 A;  4QRX A;  3MTN A;  3LFY A;  2AUZ A;  1KFX L;  3OVX A;  2OP3 A;  1O0E A;  2F7D A;  4YVA A;  4QH6 A;  2BTW B;  2HH5 A;  3K24 A;  5JH3 A;  4OW0 A;  1NB5 A;  1ATK A;  1BP4 A;  4R3D A;  4K7C A;  4ZUX U;  1AIM A;  3BCN A;  2G6D A;  1Y08 A;  4IP3 A;  2NQA A;  3PRP A;  1CB5 A;  3PBH A;  2OZ2 A;  1NLJ A;  2OUL A;  4P16 A;  3B21 A;  1QDQ A;  3KSE A;  1KXR A;  4QRV A;  3ERV A;  1NL6 A;  1Q6K A;  1K3B B;  3HHI A;  4X6I A;  4RKX A;  4YYR A;  3HWN A;  3CH2 X;  1EWM A;  2JRI A;  2AYO A;  4MZS A;  3CBJ A;  4FJC A;  2AYN A;  4N8W A;  1U9W A;  2CB5 A;  1A6R A;  1PAD A;  2J7Q A;  3WXE A;  1QXP A;  1STF E;  2R9C A;  2J7Q C;  3OVZ A;  3S3R A;  3V6E A;  5CHT A;  3TNX A;  1MDW A;  4GUA A;  4QRG A;  3P5U A;  4N79 A;  3O65 A;  3PW3 A;  2DCB A;  2HXZ A;  7PCK A;  1CTE A;  3S3Q A;  2C0Y A;  3BWK A;  2DC6 A;  1YK8 A;  3QT4 A;  1AEC A;  1MS6 A;  2XU1 A;  4HWY A;  1F2B A;  4WA6 A;  1JQP A;  4CDF B;  1PPN A;  2FYE A;  1YT7 A;  1EWO A;  2Z84 A;  2DJG B;  3TMP A;  4OEL A;  1CV8 A;  1CJL A;  1AYV A;  1Y4H A;  4BQV A;  2BTW A;  3PDF A;  3K9M A;  2DC9 A;  1TU6 A;  5PAD A;  4XZX A;  1AYW A;  3H89 A;  2AUX A;  4RF0 A;  3D6S A;  3M99 A;  9PAP A;  2DJF B;  3DF0 A;  1ZIV A;  4KLB A;  2AGA A;  4A5U A;  3IEJ A;  2R9F A;  3MOR A;  1AU3 A;  3IFU A;  1HUC B;  3IUT A;  3CH3 X; 
#chains in the Genus database with same CATH homology
 1KFU L;  4GUZ A;  1AYU A;  5EF4 A;  4X6J A;  3KW9 A;  1ICF A;  4I07 A;  1VJV A;  2XU3 A;  1QOL A;  2ARY A;  2FUD A;  3P5W A;  1U9V A;  1NB3 A;  2DC8 A;  3IHP A;  1IWD A;  2HHN A;  2VHS A;  3U8E A;  3OF9 A;  3RVX A;  4W4U A;  4BS6 A;  2Y6E A;  3AI8 A;  1VSN A;  3LXS A;  1FH0 A;  4PP1 A;  1AU0 A;  5J94 A;  1BQI A;  3IOQ A;  4DMY A;  4FIP A;  3MHH A;  2R9N A;  3KKU A;  2GFO A;  2FT2 A;  1CSB B;  2NQG A;  1BY8 A;  1SNK A;  1MEM A;  2JQF R;  2P0R A;  1EF7 A;  2VHF A;  3O1G A;  3QSD A;  2F1G A;  3KX1 A;  1DF0 A;  1F2C A;  5K16 A;  1ME4 A;  3F75 A;  3CBK A;  2G8E A;  1PPP A;  3N4C A;  2YJB A;  1YVB A;  1ITO A;  1CS8 A;  3P5X A;  3USV A;  4YYV A;  1CVZ A;  2ACT A;  1PCI A;  2P86 A;  2GHU A;  3QJ3 A;  1PE6 A;  2AVW A;  1YK7 A;  1BGO A;  1PIP A;  3HHA A;  2FTD A;  4FK5 A;  3D9W A;  4MSX A;  4I05 A;  3LTW A;  1TLO A;  5CHV A;  2DCC A;  2R9O A;  3H6S A;  4PP2 E;  2VFB A;  1U5I A;  3B79 A;  4P6E A;  2G8J A;  4BSQ A;  4YYW A;  8PCH A;  3F5V A;  1ZCM A;  4BPV A;  2NQI A;  3K8U A;  3GCB A;  5CVO B;  3BC3 A;  1KHP A;  2R6N A;  3V6C A;  3IMA A;  3C9E A;  4OEM A;  1EWP A;  1XKG A;  1F2A A;  2DZZ A;  5A24 A;  1M6D A;  2JQG R;  4AXL A;  1SP4 B;  5CVM A;  4DMX A;  1PPD A;  2E00 A;  5FPW A;  1PBH A;  4YV8 A;  3WXG A;  2H7J A;  2XU4 A;  1F29 A;  3WXF A;  4CDD B;  3N3K A;  1KHQ A;  4MZO A;  1TL9 A;  4Q8G A;  2WBF X;  3N3G A;  1W5R A;  1MEG A;  2G7Y A;  3OIS A;  2DCD A;  2IBI A;  1MHW A;  5EGW A;  2E01 A;  3KWB X;  5F02 A;  2P7U A;  2YJ9 A;  1W6F A;  1U9X A;  3O0U A;  4I04 A;  2DC7 A;  2B1M A;  4XUI A;  1THE A;  2AU1 A;  5CVN B;  3OF8 A;  1GEC E;  3MHS A;  3PNR A;  1ME3 A;  3KWZ A;  3ZUA A;  4YYS A;  1GMY A;  3P5V A;  2R9M A;  2BDZ A;  2PRE A;  3HD3 A;  3RVW A;  2YJC A;  2CIO A;  4CDE B;  2B1N A;  4QBB A;  3BPF A;  6PAD A;  2PBH A;  1U9Q X;  4RY2 A;  1POP A;  2AS8 A;  1AU4 A;  1PPO A;  1GCB A;  2O6X A;  2IPP B;  2Y5B A;  1S4V A;  3I3T A;  4X6H A;  3H8B A;  4C5P A;  4Q8H A;  1QMY A;  1NPZ A;  1E2T A;  2PNS A;  5JA7 A;  1EWL A;  1DEU A;  4XR7 A;  4N4Z A;  4W5C A;  2AIM A;  2YJ2 A;  2ATO A;  3IV2 A;  1W4T A;  1PXV A;  3BPM A;  4W5B A;  3RVV A;  1MIR A;  4G54 A;  4BS5 A;  1X9Y A;  2NQD B;  2FRQ A;  1NQC A;  3BOW A;  3E1Z B;  2XU5 A;  2HD5 A;  3NHE A;  3H8C A;  1CQD A;  2DZY A;  4YYQ A;  2FO5 A;  4CZW A;  2PAD A;  3I06 A;  1CPJ A;  1AU2 A;  3KFQ A;  4AXM A;  2VFC A;  4P6G A;  4YYU A;  2FRA A;  4PAD A;  4CDC B;  2BDL A;  1GLO A;  2DCA A;  2YJ8 A;  3H7D A;  4PI3 A;  2E03 A;  1YAL A;  2FQ9 A;  2E02 A;  4QRX A;  3MTN A;  3LFY A;  2AUZ A;  1KFX L;  3OVX A;  2OP3 A;  1O0E A;  2F7D A;  4YVA A;  4QH6 A;  2HH5 A;  3K24 A;  5JH3 A;  1NB5 A;  1ATK A;  1BP4 A;  4K7C A;  4ZUX U;  1AIM A;  3BCN A;  2G6D A;  4NV8 A;  1Y08 A;  2NQA A;  1CB5 A;  3PBH A;  2OZ2 A;  1NLJ A;  2OUL A;  1QDQ A;  3KSE A;  1KXR A;  4QRV A;  3ERV A;  1NL6 A;  1Q6K A;  1K3B B;  3HHI A;  4X6I A;  4YYR A;  3HWN A;  3CH2 X;  1EWM A;  2AYO A;  4MZS A;  4NV7 A;  3CBJ A;  4FJC A;  2AYN A;  4N8W A;  1U9W A;  2CB5 A;  1A6R A;  1PAD A;  3WXE A;  1QXP A;  1STF E;  2R9C A;  3OVZ A;  3S3R A;  3V6E A;  5CHT A;  3TNX A;  1MDW A;  4QRG A;  3P5U A;  4N79 A;  3PW3 A;  2DCB A;  2HXZ A;  7PCK A;  1CTE A;  3S3Q A;  4B55 A;  2C0Y A;  3BWK A;  2DC6 A;  1YK8 A;  3QT4 A;  1AEC A;  1MS6 A;  2XU1 A;  4HWY A;  1F2B A;  4WA6 A;  1JQP A;  4CDF B;  1PPN A;  2FYE A;  1YT7 A;  1EWO A;  2DJG B;  4OEL A;  1CV8 A;  1CJL A;  1AYV A;  1Y4H A;  4BQV A;  3PDF A;  3K9M A;  2DC9 A;  1GX3 A;  1TU6 A;  5PAD A;  1AYW A;  3H89 A;  2AUX A;  3D6S A;  3M99 A;  9PAP A;  2DJF B;  3DF0 A;  1ZIV A;  4KLB A;  2BSZ A;  3IEJ A;  2R9F A;  3MOR A;  1AU3 A;  1HUC B;  3IUT A;  4BGF A;  3CH3 X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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