3PHUA

Otu domain of crimean congo hemorrhagic fever virus
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
184
structure length
183
Chain Sequence
PMDFLRSLDWTQVIAGQYVSNPRFNISDYFEIVRQPGDGNFYHSIAELTMPNKTDHSYHYIKRLTESAARKYYQEEPEARLVGLSLEDYLKRMLSDNEWGSTLEASMLAKEMGITIIIWTVAASDEVEAGIKFGDGDVFTAVNLLHSGQTHFDALRILPQFETDTREALSLMDRVIAVDQLTS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains.
pubmed doi rcsb
molecule tags Hydrolase
source organism Crimean-congo hemorrhagic fever virus strain ibar10200
molecule keywords RNA-directed RNA polymerase L
total genus 58
structure length 183
sequence length 184
chains with identical sequence B
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 2010-11-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02338 OTU OTU-like cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.80 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cathepsin B; Chain A 3phuA01
3PRPA 3PT2A 3ZNHA 3PHUA 5JZEA 3C0RA 3PSEA 4HXDB 4BOPA 4BOZA 3TMPA 4BOSA 4BOUA 3PHXA 4BOQA 3PRMA 3PHWA 3BY4A
chains in the Genus database with same CATH superfamily
3H8BA 2E01A 1AIMA 4I04A 4ZUXU 3BPFA 3ERVA 2BTWA 2R9OA 3KW9A 4CDCB 7PCKA 3RVWA 2C0YA 1ME3A 2YJ2A 1GECE 4BOSA 2JTCA 1ICFA 3PHUA 1XKGA 2JRIA 1BP4A 1PBHA 3BBAA 1EWPA 3O0UA 1QXPA 3IUTA 3PHXA 3OVXA 1PPDA 1M6DA 1TLOA 1YK8A 1PIPA 3HD3A 2Y5BA 1S4VA 2E02A 4YYWA 2YJCA 5PADA 4QRXA 4RKXA 1CPJA 2BDZA 3CH2X 2XU5A 4PADA 3WXFA 1BQIA 2WBFX 3HHAA 2AGAA 3D6SA 4BOPA 4BS5A 2B1MA 2FRAA 4XZXA 2NQGA 2H7JA 3WXGA 3MHSA 4N8WA 2G8JA 3K24A 1PCIA 2AYNA 1DKIA 2CIOA 3LFYA 2IPPB 1CV8A 1PXVA 4AXLA 3OVZA 3CH3X 2FTDA 2OULA 2DCCA 2HD5A 2YJ9A 3P5UA 1CSBB 2FUDA 5EZSA 4CZWA 3QSDA 1U9VA 3IOQA 3N3KA 1YVBA 4CDFB 2DCAA 2PBHA 1Y08A 4X6IA 1ZIVA 1UKFA 2DZZA 1F2AA 4N4ZA 4MSXA 3C9EA 2JQFR 3KX1A 1MS6A 1NL6A 4YYSA 3U8EA 4PP2E 1EWLA 1U9QX 4OVZB 2DC7A 2F7DA 3USVA 3H89A 3P5VA 2NQIA 3OF8A 4FK5A 1PVJA 3QJ3A 1Y4HA 3ZUAA 1AYUA 4W5CA 2AS8A 3KFQA 5CVOB 8PCHA 2VHFA 2FE8A 4D8IA 2R9MA 2BDLA 2DJFB 3HHIA 4ZTBA 9PAPA 3MTNA 2E00A 1PPNA 1AU4A 2O6XA 5EF4A 1F2CA 1SP4B 3O65A 2Y6EA 3QT4A 3AI8A 3N3GA 1A6RA 1YT7A 4D8EA 3PDFA 4BPVA 1SNKA 3TMPA 2OP3A 3H8CA 1F29A 2XU1A 1QMYA 4OVZA 4KLBA 2G8EA 2XU4A 1MEGA 1THEA 3CBKA 3MP2A 2ACTA 1O0EA 4QH6A 2AYOA 2FO5A 5F02A 2Z84A 2PADA 1K3BB 3W31A 2VHSA 3S3QA 3I3TA 2BU3A 1CQDA 4RY2A 1NPZA 1ATKA 4BSQA 4BS6A 1KFUL 6PADA 3DF0A 2AUZA 2CB5A 3P5XA 1GCBA 1EWMA 1ITOA 1QOLA 3IV2A 2DC9A 3RNVA 3KKUA 4OEMA 4CDEB 3BPMA 4DMYA 3E9SA 4K7CA 1GMYA 2PREA 1AU2A 4DMXA 1MIRA 3PT2A 2E03A 3K8UA 5EGWA 2OZ2A 1MEMA 1CS8A 5KO3A 3B79A 1YK7A 3MHHA 3CBJA 1STFE 2FT2A 2ARYA 3H7DA 1VSNA 4PP1A 2ATOA 1KHPA 3PRPA 2NQDB 3OQCA 3KSEA 3PW3A 2PNSA 4YYQA 3K9MA 4X6HA 2HWKA 2FQ9A 4IP3A 1AU3A 4GUAA 2HHNA 2BTWB 5EZQA 4QRGA 3BCNA 1X9YA 1Q6KA 4G54A 4YVAA 1AU0A 4HXDB 4RF0A 2XU3A 4BOQA 2JQGR 1NB3A 2FRQA 3F5VA 4R3DA 2R9CA 1U9XA 3B21A 1HUCB 1DF0A 2YJ8A 4Q8GA 1JQPA 1KXRA 1FH0A 4REZA 1IWDA 2DOSA 1PADA 3BWKA 3TNXA 1AYWA 1NLJA 3I06A 3IHPA 4YV8A 2P7UA 3BOWA 3HWNA 3RVVA 3MTVA 3F75A 3PNRA 3BB7A 3IMAA 2YJBA 4N79A 3PHWA 2AIMA 1CTEA 4YYUA 4BQVA 3M99A 5JZEA 4FJCA 1TU6A 4P6EA 4W5BA 3V6CA 2J7QC 4BOZA 1DEUA 4XUIA 3BY4A 3ZNHA 5CHTA 1PE6A 5J94A 4YYVA 2B1NA 5K16A 1CVZA 1GLOA 2G7YA 4WURA 4I07A 3IFUA 2HH5A 4M0WA 3MORA 1F2BA 2F1GA 1CJLA 4A5UA 4YYRA 4RF1A 3O1GA 4MZSA 3BC3A 4MZOA 4AXMA 4PT5A 2DCDA 2UZJA 3N4CA 3KWBX 1ZCMA 3RVXA 3GCBA 1YZBA 3W30A 2G6DA 4WA6A 4HWYA 4X6JA 3PSEA 5E6JA 3IEJA 1NB5A 2AU1A 2GHUA 4PI3A 1POPA 4QBBA 3H6SA 2R9NA 3OISA 2P86A 5A24A 3OF9A 1BY8A 1NQCA 5FPWA 1U9WA 4MI7A 1TL9A 1QDQA 2IBIA 3LXSA 4I05A 2DZYA 2GFOA 1MDWA 2R9FA 4QRVA 5JA7A 1AYVA 3S3RA 4Q8HA 4XR7A 3P5WA 4OW0A 5CVNB 1KFXL 5CVMA 3WXEA 2DC6A 4CDDB 1AECA 1MHWA 4OELA 4IUMA 5JH3A 1PPOA 1KHQA 4FIPA 1CB5A 1U5IA 2DCBA 1PPPA 2AUXA 1VJVA 4P16A 1BGOA 4BOUA 2AVWA 3NHEA 3PRMA 4W4UA 2NQAA 2DJGB 5CHVA 4D8BA 2P0RA 2DC8A 3V6EA 2R6NA 2FYEA 4P6GA 3PBHA 4RNAA 3KWZA 3E1ZB 3C0RA 1EF7A 3TRKA 1EWOA 4MM3B 1YALA 2J7QA 2HXZA 1ME4A 3MJ5A
chains in the Genus database with same CATH topology
3E9SA 4OVZB 4A5UA 3PT2A 2BTWA 4RF1A 4PT5A 1PVJA 2UZJA 5KO3A 1YZBA 3W30A 4BOSA 2JTCA 3PRPA 3PHUA 3PSEA 3OQCA 5E6JA 2FE8A 4D8IA 2JRIA 2HWKA 4IP3A 4ZTBA 3BBAA 4GUAA 2BTWB 5EZQA 3PHXA 3O65A 4MI7A 4HXDB 4RF0A 4BOQA 4D8EA 3TMPA 4OVZA 4R3DA 3B21A 3MP2A 4RKXA 4OW0A 2AGAA 2Z84A 4REZA 2DOSA 4BOPA 3W31A 4XZXA 4IUMA 3MTVA 3BB7A 1DKIA 2BU3A 4P16A 4BOUA 3PRMA 3PHWA 4D8BA 5JZEA 2J7QC 5EZSA 4BOZA 4RNAA 3BY4A 1UKFA 3ZNHA 3C0RA 3TRKA 4MM3B 3RNVA 2J7QA 4WURA 3IFUA 4M0WA 3MJ5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PRP A;  3PT2 A;  3ZNH A;  3PHU A;  5JZE A;  3C0R A;  3PSE A;  4HXD B;  4BOP A;  4BOZ A;  3TMP A;  4BOS A;  4BOU A;  3PHX A;  4BOQ A;  3PRM A;  3PHW A;  3BY4 A; 
#chains in the Genus database with same CATH topology
 3H8B A;  2E01 A;  1AIM A;  4I04 A;  4ZUX U;  3BPF A;  3ERV A;  2BTW A;  2R9O A;  3KW9 A;  4CDC B;  7PCK A;  3RVW A;  2C0Y A;  1ME3 A;  2YJ2 A;  1GEC E;  4BOS A;  2JTC A;  1ICF A;  3PHU A;  1XKG A;  2JRI A;  1BP4 A;  1PBH A;  3BBA A;  1EWP A;  3O0U A;  1QXP A;  3IUT A;  3PHX A;  3OVX A;  1PPD A;  1M6D A;  1TLO A;  1YK8 A;  1PIP A;  3HD3 A;  2Y5B A;  1S4V A;  2E02 A;  4YYW A;  2YJC A;  5PAD A;  4QRX A;  4RKX A;  1CPJ A;  2BDZ A;  3CH2 X;  2XU5 A;  4PAD A;  3WXF A;  1BQI A;  2WBF X;  3HHA A;  2AGA A;  3D6S A;  4BOP A;  4BS5 A;  2B1M A;  2FRA A;  4XZX A;  2NQG A;  2H7J A;  3WXG A;  3MHS A;  4N8W A;  2G8J A;  3K24 A;  1PCI A;  2AYN A;  1DKI A;  2CIO A;  3LFY A;  2IPP B;  1CV8 A;  1PXV A;  4AXL A;  3OVZ A;  3CH3 X;  2FTD A;  2OUL A;  2DCC A;  2HD5 A;  2YJ9 A;  3P5U A;  1CSB B;  2FUD A;  5EZS A;  4CZW A;  3QSD A;  1U9V A;  3IOQ A;  3N3K A;  1YVB A;  4CDF B;  2DCA A;  2PBH A;  1Y08 A;  4X6I A;  1ZIV A;  1UKF A;  2DZZ A;  1F2A A;  4N4Z A;  4MSX A;  3C9E A;  2JQF R;  3KX1 A;  1MS6 A;  1NL6 A;  4YYS A;  3U8E A;  4PP2 E;  1EWL A;  1U9Q X;  4OVZ B;  2DC7 A;  2F7D A;  3USV A;  3H89 A;  3P5V A;  2NQI A;  3OF8 A;  4FK5 A;  1PVJ A;  3QJ3 A;  1Y4H A;  3ZUA A;  1AYU A;  4W5C A;  2AS8 A;  3KFQ A;  5CVO B;  8PCH A;  2VHF A;  2FE8 A;  4D8I A;  2R9M A;  2BDL A;  2DJF B;  3HHI A;  4ZTB A;  9PAP A;  3MTN A;  2E00 A;  1PPN A;  1AU4 A;  2O6X A;  5EF4 A;  1F2C A;  1SP4 B;  3O65 A;  2Y6E A;  3QT4 A;  3AI8 A;  3N3G A;  1A6R A;  1YT7 A;  4D8E A;  3PDF A;  4BPV A;  1SNK A;  3TMP A;  2OP3 A;  3H8C A;  1F29 A;  2XU1 A;  1QMY A;  4OVZ A;  4KLB A;  2G8E A;  2XU4 A;  1MEG A;  1THE A;  3CBK A;  3MP2 A;  2ACT A;  1O0E A;  4QH6 A;  2AYO A;  2FO5 A;  5F02 A;  2Z84 A;  2PAD A;  1K3B B;  3W31 A;  2VHS A;  3S3Q A;  3I3T A;  2BU3 A;  1CQD A;  4RY2 A;  1NPZ A;  1ATK A;  4BSQ A;  4BS6 A;  1KFU L;  6PAD A;  3DF0 A;  2AUZ A;  2CB5 A;  3P5X A;  1GCB A;  1EWM A;  1ITO A;  1QOL A;  3IV2 A;  2DC9 A;  3RNV A;  3KKU A;  4OEM A;  4CDE B;  3BPM A;  4DMY A;  3E9S A;  4K7C A;  1GMY A;  2PRE A;  1AU2 A;  4DMX A;  1MIR A;  3PT2 A;  2E03 A;  3K8U A;  5EGW A;  2OZ2 A;  1MEM A;  1CS8 A;  5KO3 A;  3B79 A;  1YK7 A;  3MHH A;  3CBJ A;  1STF E;  2FT2 A;  2ARY A;  3H7D A;  1VSN A;  4PP1 A;  2ATO A;  1KHP A;  3PRP A;  2NQD B;  3OQC A;  3KSE A;  3PW3 A;  2PNS A;  4YYQ A;  3K9M A;  4X6H A;  2HWK A;  2FQ9 A;  4IP3 A;  1AU3 A;  4GUA A;  2HHN A;  2BTW B;  5EZQ A;  4QRG A;  3BCN A;  1X9Y A;  1Q6K A;  4G54 A;  4YVA A;  1AU0 A;  4HXD B;  4RF0 A;  2XU3 A;  4BOQ A;  2JQG R;  1NB3 A;  2FRQ A;  3F5V A;  4R3D A;  2R9C A;  1U9X A;  3B21 A;  1HUC B;  1DF0 A;  2YJ8 A;  4Q8G A;  1JQP A;  1KXR A;  1FH0 A;  4REZ A;  1IWD A;  2DOS A;  1PAD A;  3BWK A;  3TNX A;  1AYW A;  1NLJ A;  3I06 A;  3IHP A;  4YV8 A;  2P7U A;  3BOW A;  3HWN A;  3RVV A;  3MTV A;  3F75 A;  3PNR A;  3BB7 A;  3IMA A;  2YJB A;  4N79 A;  3PHW A;  2AIM A;  1CTE A;  4YYU A;  4BQV A;  3M99 A;  5JZE A;  4FJC A;  1TU6 A;  4P6E A;  4W5B A;  3V6C A;  2J7Q C;  4BOZ A;  1DEU A;  4XUI A;  3BY4 A;  3ZNH A;  5CHT A;  1PE6 A;  5J94 A;  4YYV A;  2B1N A;  5K16 A;  1CVZ A;  1GLO A;  2G7Y A;  4WUR A;  4I07 A;  3IFU A;  2HH5 A;  4M0W A;  3MOR A;  1F2B A;  2F1G A;  1CJL A;  4A5U A;  4YYR A;  4RF1 A;  3O1G A;  4MZS A;  3BC3 A;  4MZO A;  4AXM A;  4PT5 A;  2DCD A;  2UZJ A;  3N4C A;  3KWB X;  1ZCM A;  3RVX A;  3GCB A;  1YZB A;  3W30 A;  2G6D A;  4WA6 A;  4HWY A;  4X6J A;  3PSE A;  5E6J A;  3IEJ A;  1NB5 A;  2AU1 A;  2GHU A;  4PI3 A;  1POP A;  4QBB A;  3H6S A;  2R9N A;  3OIS A;  2P86 A;  5A24 A;  3OF9 A;  1BY8 A;  1NQC A;  5FPW A;  1U9W A;  4MI7 A;  1TL9 A;  1QDQ A;  2IBI A;  3LXS A;  4I05 A;  2DZY A;  2GFO A;  1MDW A;  2R9F A;  4QRV A;  5JA7 A;  1AYV A;  3S3R A;  4Q8H A;  4XR7 A;  3P5W A;  4OW0 A;  5CVN B;  1KFX L;  5CVM A;  3WXE A;  2DC6 A;  4CDD B;  1AEC A;  1MHW A;  4OEL A;  4IUM A;  5JH3 A;  1PPO A;  1KHQ A;  4FIP A;  1CB5 A;  1U5I A;  2DCB A;  1PPP A;  2AUX A;  1VJV A;  4P16 A;  1BGO A;  4BOU A;  2AVW A;  3NHE A;  3PRM A;  4W4U A;  2NQA A;  2DJG B;  5CHV A;  4D8B A;  2P0R A;  2DC8 A;  3V6E A;  2R6N A;  2FYE A;  4P6G A;  3PBH A;  4RNA A;  3KWZ A;  3E1Z B;  3C0R A;  1EF7 A;  3TRK A;  1EWO A;  4MM3 B;  1YAL A;  2J7Q A;  2HXZ A;  1ME4 A;  3MJ5 A; 
#chains in the Genus database with same CATH homology
 3E9S A;  4OVZ B;  4A5U A;  3PT2 A;  2BTW A;  4RF1 A;  4PT5 A;  1PVJ A;  2UZJ A;  5KO3 A;  1YZB A;  3W30 A;  4BOS A;  2JTC A;  3PRP A;  3PHU A;  3PSE A;  3OQC A;  5E6J A;  2FE8 A;  4D8I A;  2JRI A;  2HWK A;  4IP3 A;  4ZTB A;  3BBA A;  4GUA A;  2BTW B;  5EZQ A;  3PHX A;  3O65 A;  4MI7 A;  4HXD B;  4RF0 A;  4BOQ A;  4D8E A;  3TMP A;  4OVZ A;  4R3D A;  3B21 A;  3MP2 A;  4RKX A;  4OW0 A;  2AGA A;  2Z84 A;  4REZ A;  2DOS A;  4BOP A;  3W31 A;  4XZX A;  4IUM A;  3MTV A;  3BB7 A;  1DKI A;  2BU3 A;  4P16 A;  4BOU A;  3PRM A;  3PHW A;  4D8B A;  5JZE A;  2J7Q C;  5EZS A;  4BOZ A;  4RNA A;  3BY4 A;  1UKF A;  3ZNH A;  3C0R A;  3TRK A;  4MM3 B;  3RNV A;  2J7Q A;  4WUR A;  3IFU A;  4M0W A;  3MJ5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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