3PSEA

Structure of a viral otu domain protease bound to interferon-stimulated gene 15 (isg15)
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
164
structure length
164
Chain Sequence
GPMDFLRSLDWTQVIAGQYVSNPRFNISDYFEIVRQPGDGNCFYHSIAELTMPNKTDHSYHYIKRLTESAARKYYQEEPEARLVGLSLEDYLKRMLSDNEWGSTLEASMLAKEMGITIIIWTVAASDEVEAGIKFGDGDVFTAVNLLHSGQTHFDALRILPQFE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease.
pubmed doi rcsb
molecule tags Hydrolase/protein binding
source organism Crimean-congo hemorrhagic fever virus
molecule keywords RNA polymerase
total genus 48
structure length 164
sequence length 164
ec nomenclature
pdb deposition date 2010-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02338 OTU OTU-like cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.80 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cathepsin B; Chain A 3pseA00
4BOUA 4BOPA 4BOZA 4BOQA 3PHUA 3PHWA 3BY4A 3PRPA 4HXDB 4BOSA 5JZEA 3PT2A 3ZNHA 3PHXA 3TMPA 3PSEA 3PRMA 3C0RA
chains in the Genus database with same CATH superfamily
2R9MA 2FUDA 4D8IA 4XR7A 2OP3A 3O1GA 4QBBA 1ME3A 2FT2A 2AGAA 4PP2E 2R9NA 4M0WA 1ME4A 3MTVA 4REZA 1Y08A 2BTWA 5CVNB 1AECA 3ERVA 1KXRA 1NQCA 2ARYA 3C9EA 2DCDA 3K9MA 4MSXA 2XU1A 3PSEA 2DJGB 1NL6A 1U9XA 2IBIA 4RNAA 3RNVA 1CB5A 3IEJA 3PBHA 1GECE 1KHPA 1YVBA 4CDCB 1U9WA 1PBHA 2PREA 2OZ2A 3KWZA 2AYOA 1MIRA 3ZNHA 5JH3A 3DF0A 1PPPA 4DMXA 3B21A 3IUTA 4YV8A 5CHVA 3PNRA 2Z84A 2P7UA 1YK7A 2CB5A 2OULA 1THEA 3BPFA 2J7QC 1O0EA 5CHTA 2BDLA 2YJ9A 3RVWA 4BS5A 2WBFX 1KFUL 4K7CA 3KWBX 1ZCMA 2PADA 3KFQA 1PXVA 3CH3X 1IWDA 1TU6A 2NQAA 1VSNA 3RVXA 4OVZB 4AXLA 4A5UA 1STFE 3WXFA 2J7QA 3PDFA 2R9FA 1BGOA 3OQCA 3LFYA 4YYRA 1PPOA 5JA7A 3AI8A 4HWYA 1MEMA 1F2CA 2HH5A 2DC9A 2AU1A 3NHEA 5K16A 1POPA 1QMYA 3ZUAA 2DC8A 4OELA 1GLOA 5EGWA 3BC3A 5J94A 1QDQA 4I05A 1VJVA 4PT5A 4YYSA 2P0RA 3PHXA 3IFUA 1PE6A 1TL9A 3K24A 3P5UA 1KFXL 1YALA 3IHPA 1YT7A 1A6RA 1CPJA 4X6JA 3IOQA 1AIMA 4D8BA 3O65A 2FE8A 3PW3A 1AYUA 3D6SA 3KX1A 2B1MA 3HHAA 4XUIA 1PPDA 4P16A 3MTNA 1TLOA 3PHWA 2FO5A 3LXSA 1MDWA 2YJCA 1NB3A 1EWOA 3CBKA 3TMPA 1AYWA 3H7DA 1F29A 4BSQA 4YYVA 2G8EA 3W31A 1CS8A 4CDEB 3V6CA 2O6XA 4R3DA 1FH0A 3WXGA 2E03A 5CVOB 1GCBA 4X6IA 3PRMA 2P86A 1U5IA 3KKUA 2YJBA 4IP3A 1EWPA 2E02A 4WA6A 4RY2A 2R9CA 4QH6A 1NLJA 2DOSA 3OF9A 4N4ZA 3OVXA 1PADA 3N3KA 2YJ8A 1JQPA 1MEGA 4OEMA 2DZYA 3HD3A 3BY4A 4W5BA 4FK5A 3MHSA 2Y6EA 4RF0A 3PRPA 2HWKA 4OW0A 3QT4A 3MP2A 2JTCA 1BP4A 3S3QA 1F2AA 3K8UA 1CTEA 1DEUA 3H8BA 3HHIA 2G6DA 4I04A 3I06A 4PP1A 3BBAA 4BQVA 5KO3A 4YVAA 3E1ZB 2BTWB 4I07A 4KLBA 1ZIVA 2DJFB 2JRIA 4G54A 3OF8A 1AU2A 2FRQA 2JQFR 5JZEA 1BY8A 3RVVA 2BU3A 4BOSA 3WXEA 8PCHA 2R6NA 4RKXA 2BDZA 4ZUXU 3CBJA 2DZZA 2ATOA 2IPPB 3P5XA 3TRKA 4P6GA 4X6HA 4YYUA 1U9QX 1SP4B 2VHSA 1PCIA 2GHUA 2NQDB 2UZJA 5EZSA 3I3TA 4QRXA 2PNSA 3U8EA 4YYWA 2PBHA 1U9VA 4Q8HA 5PADA 3H8CA 3OVZA 2E01A 2AS8A 9PAPA 1MS6A 4OVZA 1QOLA 5CVMA 1ATKA 5FPWA 1Y4HA 2DC7A 3P5WA 4CZWA 3N3GA 1X9YA 3KSEA 1AYVA 3BPMA 2DCCA 5F02A 3IV2A 2FYEA 1ITOA 5EZQA 1F2BA 3H89A 1CQDA 3MJ5A 1SNKA 2HD5A 4GUAA 2B1NA 2CIOA 2YJ2A 2R9OA 4PI3A 4MZSA 2HXZA 4BPVA 4BS6A 2AUZA 4YYQA 3B79A 3F75A 2XU3A 1EF7A 4PADA 1NB5A 7PCKA 3BCNA 1NPZA 4QRVA 3H6SA 2JQGR 4HXDB 4ZTBA 2G7YA 2FQ9A 1HUCB 4BOQA 4RF1A 3MORA 2GFOA 1CSBB 2NQIA 2FTDA 2NQGA 3W30A 2XU5A 3M99A 4N8WA 4CDDB 1CVZA 4FJCA 2H7JA 4MM3B 3F5VA 4P6EA 1YK8A 4Q8GA 3N4CA 1EWLA 4MZOA 1PVJA 4QRGA 3C0RA 6PADA 1DF0A 4BOUA 1YZBA 1AU4A 2DC6A 5A24A 1CJLA 1ICFA 5E6JA 2XU4A 2VHFA 4AXMA 1PIPA 3KW9A 3GCBA 2AUXA 1BQIA 2AVWA 1Q6KA 2FRAA 1DKIA 3BOWA 2G8JA 4XZXA 3PHUA 3BWKA 3V6EA 1AU3A 4WURA 1EWMA 2AIMA 3HWNA 4BOZA 4W5CA 2AYNA 4FIPA 3S3RA 4BOPA 2F1GA 4DMYA 4D8EA 1K3BB 2DCAA 3O0UA 3USVA 1PPNA 4CDFB 1KHQA 2C0YA 3CH2X 1CV8A 1QXPA 3MHHA 3OISA 2HHNA 1S4VA 3IMAA 3PT2A 3TNXA 1M6DA 2F7DA 2Y5BA 3BB7A 1MHWA 1XKGA 2DCBA 2E00A 5EF4A 3QJ3A 3P5VA 4W4UA 3E9SA 1GMYA 4N79A 1UKFA 1AU0A 2ACTA 3QSDA 4IUMA 4MI7A
chains in the Genus database with same CATH topology
4D8IA 3BBAA 4PT5A 3PHXA 4HXDB 4ZTBA 2AGAA 3IFUA 4M0WA 4BOQA 3MTVA 4RF1A 5KO3A 4REZA 2BTWA 3W30A 2BTWB 3PSEA 2JRIA 5JZEA 4MM3B 4D8BA 2BU3A 3O65A 3RNVA 4RNAA 4BOSA 2FE8A 4RKXA 1PVJA 4P16A 3C0RA 3TRKA 4BOUA 3PHWA 1YZBA 3ZNHA 5E6JA 3B21A 2Z84A 2UZJA 5EZSA 3TMPA 2J7QC 3W31A 1DKIA 4XZXA 3PHUA 4R3DA 4WURA 4BOZA 4BOPA 4OVZA 4D8EA 4OVZB 3PRMA 4A5UA 2J7QA 4IP3A 3OQCA 5EZQA 2DOSA 3PT2A 3MJ5A 3BB7A 4GUAA 3BY4A 4RF0A 3E9SA 3PRPA 2HWKA 4OW0A 3MP2A 1UKFA 2JTCA 4IUMA 4MI7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BOU A;  4BOP A;  4BOZ A;  4BOQ A;  3PHU A;  3PHW A;  3BY4 A;  3PRP A;  4HXD B;  4BOS A;  5JZE A;  3PT2 A;  3ZNH A;  3PHX A;  3TMP A;  3PSE A;  3PRM A;  3C0R A; 
#chains in the Genus database with same CATH topology
 2R9M A;  2FUD A;  4D8I A;  4XR7 A;  2OP3 A;  3O1G A;  4QBB A;  1ME3 A;  2FT2 A;  2AGA A;  4PP2 E;  2R9N A;  4M0W A;  1ME4 A;  3MTV A;  4REZ A;  1Y08 A;  2BTW A;  5CVN B;  1AEC A;  3ERV A;  1KXR A;  1NQC A;  2ARY A;  3C9E A;  2DCD A;  3K9M A;  4MSX A;  2XU1 A;  3PSE A;  2DJG B;  1NL6 A;  1U9X A;  2IBI A;  4RNA A;  3RNV A;  1CB5 A;  3IEJ A;  3PBH A;  1GEC E;  1KHP A;  1YVB A;  4CDC B;  1U9W A;  1PBH A;  2PRE A;  2OZ2 A;  3KWZ A;  2AYO A;  1MIR A;  3ZNH A;  5JH3 A;  3DF0 A;  1PPP A;  4DMX A;  3B21 A;  3IUT A;  4YV8 A;  5CHV A;  3PNR A;  2Z84 A;  2P7U A;  1YK7 A;  2CB5 A;  2OUL A;  1THE A;  3BPF A;  2J7Q C;  1O0E A;  5CHT A;  2BDL A;  2YJ9 A;  3RVW A;  4BS5 A;  2WBF X;  1KFU L;  4K7C A;  3KWB X;  1ZCM A;  2PAD A;  3KFQ A;  1PXV A;  3CH3 X;  1IWD A;  1TU6 A;  2NQA A;  1VSN A;  3RVX A;  4OVZ B;  4AXL A;  4A5U A;  1STF E;  3WXF A;  2J7Q A;  3PDF A;  2R9F A;  1BGO A;  3OQC A;  3LFY A;  4YYR A;  1PPO A;  5JA7 A;  3AI8 A;  4HWY A;  1MEM A;  1F2C A;  2HH5 A;  2DC9 A;  2AU1 A;  3NHE A;  5K16 A;  1POP A;  1QMY A;  3ZUA A;  2DC8 A;  4OEL A;  1GLO A;  5EGW A;  3BC3 A;  5J94 A;  1QDQ A;  4I05 A;  1VJV A;  4PT5 A;  4YYS A;  2P0R A;  3PHX A;  3IFU A;  1PE6 A;  1TL9 A;  3K24 A;  3P5U A;  1KFX L;  1YAL A;  3IHP A;  1YT7 A;  1A6R A;  1CPJ A;  4X6J A;  3IOQ A;  1AIM A;  4D8B A;  3O65 A;  2FE8 A;  3PW3 A;  1AYU A;  3D6S A;  3KX1 A;  2B1M A;  3HHA A;  4XUI A;  1PPD A;  4P16 A;  3MTN A;  1TLO A;  3PHW A;  2FO5 A;  3LXS A;  1MDW A;  2YJC A;  1NB3 A;  1EWO A;  3CBK A;  3TMP A;  1AYW A;  3H7D A;  1F29 A;  4BSQ A;  4YYV A;  2G8E A;  3W31 A;  1CS8 A;  4CDE B;  3V6C A;  2O6X A;  4R3D A;  1FH0 A;  3WXG A;  2E03 A;  5CVO B;  1GCB A;  4X6I A;  3PRM A;  2P86 A;  1U5I A;  3KKU A;  2YJB A;  4IP3 A;  1EWP A;  2E02 A;  4WA6 A;  4RY2 A;  2R9C A;  4QH6 A;  1NLJ A;  2DOS A;  3OF9 A;  4N4Z A;  3OVX A;  1PAD A;  3N3K A;  2YJ8 A;  1JQP A;  1MEG A;  4OEM A;  2DZY A;  3HD3 A;  3BY4 A;  4W5B A;  4FK5 A;  3MHS A;  2Y6E A;  4RF0 A;  3PRP A;  2HWK A;  4OW0 A;  3QT4 A;  3MP2 A;  2JTC A;  1BP4 A;  3S3Q A;  1F2A A;  3K8U A;  1CTE A;  1DEU A;  3H8B A;  3HHI A;  2G6D A;  4I04 A;  3I06 A;  4PP1 A;  3BBA A;  4BQV A;  5KO3 A;  4YVA A;  3E1Z B;  2BTW B;  4I07 A;  4KLB A;  1ZIV A;  2DJF B;  2JRI A;  4G54 A;  3OF8 A;  1AU2 A;  2FRQ A;  2JQF R;  5JZE A;  1BY8 A;  3RVV A;  2BU3 A;  4BOS A;  3WXE A;  8PCH A;  2R6N A;  4RKX A;  2BDZ A;  4ZUX U;  3CBJ A;  2DZZ A;  2ATO A;  2IPP B;  3P5X A;  3TRK A;  4P6G A;  4X6H A;  4YYU A;  1U9Q X;  1SP4 B;  2VHS A;  1PCI A;  2GHU A;  2NQD B;  2UZJ A;  5EZS A;  3I3T A;  4QRX A;  2PNS A;  3U8E A;  4YYW A;  2PBH A;  1U9V A;  4Q8H A;  5PAD A;  3H8C A;  3OVZ A;  2E01 A;  2AS8 A;  9PAP A;  1MS6 A;  4OVZ A;  1QOL A;  5CVM A;  1ATK A;  5FPW A;  1Y4H A;  2DC7 A;  3P5W A;  4CZW A;  3N3G A;  1X9Y A;  3KSE A;  1AYV A;  3BPM A;  2DCC A;  5F02 A;  3IV2 A;  2FYE A;  1ITO A;  5EZQ A;  1F2B A;  3H89 A;  1CQD A;  3MJ5 A;  1SNK A;  2HD5 A;  4GUA A;  2B1N A;  2CIO A;  2YJ2 A;  2R9O A;  4PI3 A;  4MZS A;  2HXZ A;  4BPV A;  4BS6 A;  2AUZ A;  4YYQ A;  3B79 A;  3F75 A;  2XU3 A;  1EF7 A;  4PAD A;  1NB5 A;  7PCK A;  3BCN A;  1NPZ A;  4QRV A;  3H6S A;  2JQG R;  4HXD B;  4ZTB A;  2G7Y A;  2FQ9 A;  1HUC B;  4BOQ A;  4RF1 A;  3MOR A;  2GFO A;  1CSB B;  2NQI A;  2FTD A;  2NQG A;  3W30 A;  2XU5 A;  3M99 A;  4N8W A;  4CDD B;  1CVZ A;  4FJC A;  2H7J A;  4MM3 B;  3F5V A;  4P6E A;  1YK8 A;  4Q8G A;  3N4C A;  1EWL A;  4MZO A;  1PVJ A;  4QRG A;  3C0R A;  6PAD A;  1DF0 A;  4BOU A;  1YZB A;  1AU4 A;  2DC6 A;  5A24 A;  1CJL A;  1ICF A;  5E6J A;  2XU4 A;  2VHF A;  4AXM A;  1PIP A;  3KW9 A;  3GCB A;  2AUX A;  1BQI A;  2AVW A;  1Q6K A;  2FRA A;  1DKI A;  3BOW A;  2G8J A;  4XZX A;  3PHU A;  3BWK A;  3V6E A;  1AU3 A;  4WUR A;  1EWM A;  2AIM A;  3HWN A;  4BOZ A;  4W5C A;  2AYN A;  4FIP A;  3S3R A;  4BOP A;  2F1G A;  4DMY A;  4D8E A;  1K3B B;  2DCA A;  3O0U A;  3USV A;  1PPN A;  4CDF B;  1KHQ A;  2C0Y A;  3CH2 X;  1CV8 A;  1QXP A;  3MHH A;  3OIS A;  2HHN A;  1S4V A;  3IMA A;  3PT2 A;  3TNX A;  1M6D A;  2F7D A;  2Y5B A;  3BB7 A;  1MHW A;  1XKG A;  2DCB A;  2E00 A;  5EF4 A;  3QJ3 A;  3P5V A;  4W4U A;  3E9S A;  1GMY A;  4N79 A;  1UKF A;  1AU0 A;  2ACT A;  3QSD A;  4IUM A;  4MI7 A; 
#chains in the Genus database with same CATH homology
 4D8I A;  3BBA A;  4PT5 A;  3PHX A;  4HXD B;  4ZTB A;  2AGA A;  3IFU A;  4M0W A;  4BOQ A;  3MTV A;  4RF1 A;  5KO3 A;  4REZ A;  2BTW A;  3W30 A;  2BTW B;  3PSE A;  2JRI A;  5JZE A;  4MM3 B;  4D8B A;  2BU3 A;  3O65 A;  3RNV A;  4RNA A;  4BOS A;  2FE8 A;  4RKX A;  1PVJ A;  4P16 A;  3C0R A;  3TRK A;  4BOU A;  3PHW A;  1YZB A;  3ZNH A;  5E6J A;  3B21 A;  2Z84 A;  2UZJ A;  5EZS A;  3TMP A;  2J7Q C;  3W31 A;  1DKI A;  4XZX A;  3PHU A;  4R3D A;  4WUR A;  4BOZ A;  4BOP A;  4OVZ A;  4D8E A;  4OVZ B;  3PRM A;  4A5U A;  2J7Q A;  4IP3 A;  3OQC A;  5EZQ A;  2DOS A;  3PT2 A;  3MJ5 A;  3BB7 A;  4GUA A;  3BY4 A;  4RF0 A;  3E9S A;  3PRP A;  2HWK A;  4OW0 A;  3MP2 A;  1UKF A;  2JTC A;  4IUM A;  4MI7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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