3PT2A

Structure of a viral otu domain protease bound to ubiquitin
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
164
structure length
164
Chain Sequence
PGMDFLRSLDWTQVIAGQYVSNPRFNISDYFEIVRQPGDGNCFYHSIAELTMPNKTDHSYHYIKRLTESAARKYYQEEPEARLVGLSLEDYLKRMLSDNEWGSTLEASMLAKEMGITIIIWTVAASDEVEAGIKFGDGDVFTAVNLLHSGQTHFDALRILPQFE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease.
pubmed doi rcsb
molecule tags Hydrolase/protein binding
source organism Crimean-congo hemorrhagic fever virus
molecule keywords RNA polymerase
total genus 46
structure length 164
sequence length 164
ec nomenclature
pdb deposition date 2010-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02338 OTU OTU-like cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.80 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cathepsin B; Chain A 3pt2A00
4HXDB 3ZNHA 3PHXA 3PHWA 3C0RA 4BOZA 5JZEA 3PRMA 3TMPA 3PSEA 3PHUA 3PRPA 3BY4A 3PT2A 4BOSA 4BOPA 4BOUA 4BOQA
chains in the Genus database with same CATH superfamily
4MSXA 3B21A 4YYRA 3BWKA 2VHFA 2O6XA 1NPZA 2FRQA 1CPJA 4YV8A 2R9OA 1MHWA 1PADA 4QRGA 4D8IA 4OVZB 2G8JA 4CDDB 3OISA 2HXZA 4PP2E 5CHTA 1THEA 2FE8A 3S3QA 2JQGR 3P5WA 1S4VA 4K7CA 2FRAA 4X6IA 4DMXA 2GFOA 2YJ9A 4MI7A 3OF9A 4XR7A 1F2BA 1ME3A 3MORA 3I3TA 1U9VA 1EWPA 2WBFX 1KXRA 5K16A 2FUDA 4R3DA 3I06A 2DZYA 2G8EA 5CVOB 5E6JA 1FH0A 2NQGA 1EWLA 5JA7A 1BY8A 9PAPA 1CJLA 1MIRA 4AXMA 1F29A 1Y4HA 4P16A 4KLBA 1CVZA 1STFE 1NLJA 1DF0A 3IEJA 2P7UA 2BTWB 1NL6A 2JQFR 1CV8A 1AYWA 1AYUA 4XZXA 1ZIVA 3PRMA 1GMYA 1EF7A 4QBBA 4D8EA 1HUCB 2DCBA 1YZBA 2BDLA 4IUMA 1XKGA 1ME4A 2G6DA 1DKIA 2F7DA 4FIPA 2Y6EA 3RVXA 1GLOA 1PPNA 1PPDA 1VSNA 4G54A 4P6EA 5F02A 2DCDA 1CQDA 3PNRA 2AGAA 1PIPA 3IHPA 3P5UA 2FO5A 1GECE 4X6JA 2NQIA 3QSDA 4OELA 2J7QC 3CBKA 3PDFA 4W5BA 3F5VA 4X6HA 1X9YA 1AYVA 3E9SA 3LFYA 6PADA 2E00A 3QT4A 1AU4A 2NQDB 2AU1A 1AU2A 4MZSA 2DCCA 4W4UA 3OVZA 4YYWA 3BY4A 5CVMA 4QRVA 3HHIA 1YVBA 2Z84A 3MTVA 2CIOA 1AECA 2R6NA 1TU6A 3M99A 3CBJA 3TMPA 5EZSA 3P5XA 4BSQA 1YK7A 2YJBA 3N4CA 4YYVA 2DJFB 3B79A 4GUAA 3USVA 3KWBX 2F1GA 1U9XA 1QMYA 3C0RA 5A24A 8PCHA 1PCIA 3RNVA 3W30A 3C9EA 3KSEA 3NHEA 3BBAA 4RF1A 2P86A 4BQVA 3QJ3A 2OZ2A 3K9MA 3OVXA 2JRIA 3MHHA 3ZUAA 3LXSA 3GCBA 3PHUA 2HD5A 2AS8A 1SNKA 1U9QX 3DF0A 2B1MA 3HHAA 2UZJA 3IOQA 1ATKA 5CHVA 1NB5A 3ZNHA 3BCNA 2E01A 3OF8A 2Y5BA 3BOWA 1PE6A 5JZEA 3ERVA 1BGOA 3IV2A 2DCAA 1PXVA 3E1ZB 3WXFA 2VHSA 1VJVA 3CH3X 3O0UA 3H6SA 4YYUA 3TRKA 1YK8A 3KKUA 4W5CA 4WA6A 5CVNB 1ICFA 1PPOA 3RVWA 2P0RA 3KFQA 3CH2X 1CSBB 5JH3A 4CDEB 4Q8HA 1IWDA 4I05A 1U9WA 4CZWA 3H89A 2BDZA 1MEGA 1K3BB 2AUZA 2HH5A 2AUXA 3HD3A 1NQCA 3MTNA 1KHQA 4P6GA 1SP4B 1NB3A 4REZA 4CDFB 4BS6A 3MHSA 4PP1A 1YALA 1CS8A 3IFUA 2OP3A 2G7YA 2XU5A 3BPMA 4RNAA 4N4ZA 4FK5A 4AXLA 2HHNA 2PBHA 3MP2A 2GHUA 1MDWA 2H7JA 4OW0A 7PCKA 1O0EA 2XU3A 2IBIA 1KFUL 1AU3A 5EZQA 1TL9A 2FT2A 4Q8GA 2DC7A 2YJ2A 2PREA 3F75A 4N79A 3WXGA 1AIMA 3KW9A 2FQ9A 3O65A 4I07A 3RVVA 2AYNA 3H7DA 1PPPA 2DZZA 1BQIA 1YT7A 2B1NA 2DC6A 5J94A 4BOUA 5PADA 2XU4A 5EF4A 4MZOA 3PT2A 4A5UA 4M0WA 4RY2A 4HXDB 4IP3A 1U5IA 1POPA 4BPVA 3D6SA 5FPWA 1EWMA 1EWOA 4RF0A 4PADA 4DMYA 4YVAA 3PRPA 4ZTBA 2DOSA 2CB5A 1F2AA 4BOSA 4HWYA 3N3KA 5EGWA 1PVJA 4FJCA 3P5VA 1MEMA 2FTDA 2C0YA 2R9FA 4YYSA 4I04A 3PHXA 2FYEA 3IUTA 3O1GA 4BOPA 3HWNA 4OEMA 2DC8A 4PI3A 4BOQA 3PBHA 5KO3A 2YJ8A 2J7QA 2PNSA 2DJGB 1GCBA 1QDQA 1M6DA 4CDCB 4WURA 2JTCA 1BP4A 2R9CA 4PT5A 2IPPB 4QH6A 2DC9A 1QOLA 4BS5A 2AIMA 4OVZA 1QXPA 3PSEA 3KWZA 3BB7A 3N3GA 3S3RA 4D8BA 3BPFA 3PHWA 1AU0A 1Y08A 2YJCA 1F2CA 1JQPA 3K8UA 2R9MA 1DEUA 2ATOA 1KHPA 3AI8A 3H8CA 3TNXA 1ZCMA 2ARYA 3OQCA 3BC3A 4RKXA 1UKFA 1Q6KA 3MJ5A 4N8WA 3KX1A 3H8BA 3V6CA 4XUIA 2NQAA 3PW3A 3WXEA 2E03A 2XU1A 1CTEA 2BU3A 2PADA 4YYQA 2ACTA 4MM3B 4BOZA 1ITOA 1MS6A 2R9NA 4ZUXU 2OULA 1CB5A 1TLOA 3U8EA 4QRXA 1A6RA 2AYOA 2BTWA 3K24A 2HWKA 3W31A 2E02A 3IMAA 2AVWA 3V6EA 1PBHA 1KFXL
chains in the Genus database with same CATH topology
1PVJA 3B21A 3PHXA 2J7QC 4BOPA 3E9SA 4D8IA 4OVZB 4BOQA 4REZA 2FE8A 5KO3A 2J7QA 3IFUA 4RNAA 4WURA 2JTCA 3BY4A 3MP2A 4MI7A 2Z84A 3MTVA 4PT5A 4OW0A 4OVZA 3TMPA 5EZSA 3PSEA 3BB7A 4R3DA 5EZQA 4D8BA 5E6JA 3PHWA 4GUAA 3O65A 3C0RA 4P16A 3RNVA 3W30A 3BBAA 4RF1A 3OQCA 4BOUA 4RKXA 1UKFA 2JRIA 3MJ5A 2BTWB 3PHUA 3PT2A 4A5UA 4M0WA 4HXDB 4XZXA 4IP3A 3PRMA 2UZJA 4D8EA 3ZNHA 1YZBA 4IUMA 4RF0A 2BU3A 1DKIA 4MM3B 4BOZA 5JZEA 3PRPA 4ZTBA 2BTWA 2DOSA 2HWKA 3TRKA 3W31A 4BOSA 2AGAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HXD B;  3ZNH A;  3PHX A;  3PHW A;  3C0R A;  4BOZ A;  5JZE A;  3PRM A;  3TMP A;  3PSE A;  3PHU A;  3PRP A;  3BY4 A;  3PT2 A;  4BOS A;  4BOP A;  4BOU A;  4BOQ A; 
#chains in the Genus database with same CATH topology
 4MSX A;  3B21 A;  4YYR A;  3BWK A;  2VHF A;  2O6X A;  1NPZ A;  2FRQ A;  1CPJ A;  4YV8 A;  2R9O A;  1MHW A;  1PAD A;  4QRG A;  4D8I A;  4OVZ B;  2G8J A;  4CDD B;  3OIS A;  2HXZ A;  4PP2 E;  5CHT A;  1THE A;  2FE8 A;  3S3Q A;  2JQG R;  3P5W A;  1S4V A;  4K7C A;  2FRA A;  4X6I A;  4DMX A;  2GFO A;  2YJ9 A;  4MI7 A;  3OF9 A;  4XR7 A;  1F2B A;  1ME3 A;  3MOR A;  3I3T A;  1U9V A;  1EWP A;  2WBF X;  1KXR A;  5K16 A;  2FUD A;  4R3D A;  3I06 A;  2DZY A;  2G8E A;  5CVO B;  5E6J A;  1FH0 A;  2NQG A;  1EWL A;  5JA7 A;  1BY8 A;  9PAP A;  1CJL A;  1MIR A;  4AXM A;  1F29 A;  1Y4H A;  4P16 A;  4KLB A;  1CVZ A;  1STF E;  1NLJ A;  1DF0 A;  3IEJ A;  2P7U A;  2BTW B;  1NL6 A;  2JQF R;  1CV8 A;  1AYW A;  1AYU A;  4XZX A;  1ZIV A;  3PRM A;  1GMY A;  1EF7 A;  4QBB A;  4D8E A;  1HUC B;  2DCB A;  1YZB A;  2BDL A;  4IUM A;  1XKG A;  1ME4 A;  2G6D A;  1DKI A;  2F7D A;  4FIP A;  2Y6E A;  3RVX A;  1GLO A;  1PPN A;  1PPD A;  1VSN A;  4G54 A;  4P6E A;  5F02 A;  2DCD A;  1CQD A;  3PNR A;  2AGA A;  1PIP A;  3IHP A;  3P5U A;  2FO5 A;  1GEC E;  4X6J A;  2NQI A;  3QSD A;  4OEL A;  2J7Q C;  3CBK A;  3PDF A;  4W5B A;  3F5V A;  4X6H A;  1X9Y A;  1AYV A;  3E9S A;  3LFY A;  6PAD A;  2E00 A;  3QT4 A;  1AU4 A;  2NQD B;  2AU1 A;  1AU2 A;  4MZS A;  2DCC A;  4W4U A;  3OVZ A;  4YYW A;  3BY4 A;  5CVM A;  4QRV A;  3HHI A;  1YVB A;  2Z84 A;  3MTV A;  2CIO A;  1AEC A;  2R6N A;  1TU6 A;  3M99 A;  3CBJ A;  3TMP A;  5EZS A;  3P5X A;  4BSQ A;  1YK7 A;  2YJB A;  3N4C A;  4YYV A;  2DJF B;  3B79 A;  4GUA A;  3USV A;  3KWB X;  2F1G A;  1U9X A;  1QMY A;  3C0R A;  5A24 A;  8PCH A;  1PCI A;  3RNV A;  3W30 A;  3C9E A;  3KSE A;  3NHE A;  3BBA A;  4RF1 A;  2P86 A;  4BQV A;  3QJ3 A;  2OZ2 A;  3K9M A;  3OVX A;  2JRI A;  3MHH A;  3ZUA A;  3LXS A;  3GCB A;  3PHU A;  2HD5 A;  2AS8 A;  1SNK A;  1U9Q X;  3DF0 A;  2B1M A;  3HHA A;  2UZJ A;  3IOQ A;  1ATK A;  5CHV A;  1NB5 A;  3ZNH A;  3BCN A;  2E01 A;  3OF8 A;  2Y5B A;  3BOW A;  1PE6 A;  5JZE A;  3ERV A;  1BGO A;  3IV2 A;  2DCA A;  1PXV A;  3E1Z B;  3WXF A;  2VHS A;  1VJV A;  3CH3 X;  3O0U A;  3H6S A;  4YYU A;  3TRK A;  1YK8 A;  3KKU A;  4W5C A;  4WA6 A;  5CVN B;  1ICF A;  1PPO A;  3RVW A;  2P0R A;  3KFQ A;  3CH2 X;  1CSB B;  5JH3 A;  4CDE B;  4Q8H A;  1IWD A;  4I05 A;  1U9W A;  4CZW A;  3H89 A;  2BDZ A;  1MEG A;  1K3B B;  2AUZ A;  2HH5 A;  2AUX A;  3HD3 A;  1NQC A;  3MTN A;  1KHQ A;  4P6G A;  1SP4 B;  1NB3 A;  4REZ A;  4CDF B;  4BS6 A;  3MHS A;  4PP1 A;  1YAL A;  1CS8 A;  3IFU A;  2OP3 A;  2G7Y A;  2XU5 A;  3BPM A;  4RNA A;  4N4Z A;  4FK5 A;  4AXL A;  2HHN A;  2PBH A;  3MP2 A;  2GHU A;  1MDW A;  2H7J A;  4OW0 A;  7PCK A;  1O0E A;  2XU3 A;  2IBI A;  1KFU L;  1AU3 A;  5EZQ A;  1TL9 A;  2FT2 A;  4Q8G A;  2DC7 A;  2YJ2 A;  2PRE A;  3F75 A;  4N79 A;  3WXG A;  1AIM A;  3KW9 A;  2FQ9 A;  3O65 A;  4I07 A;  3RVV A;  2AYN A;  3H7D A;  1PPP A;  2DZZ A;  1BQI A;  1YT7 A;  2B1N A;  2DC6 A;  5J94 A;  4BOU A;  5PAD A;  2XU4 A;  5EF4 A;  4MZO A;  3PT2 A;  4A5U A;  4M0W A;  4RY2 A;  4HXD B;  4IP3 A;  1U5I A;  1POP A;  4BPV A;  3D6S A;  5FPW A;  1EWM A;  1EWO A;  4RF0 A;  4PAD A;  4DMY A;  4YVA A;  3PRP A;  4ZTB A;  2DOS A;  2CB5 A;  1F2A A;  4BOS A;  4HWY A;  3N3K A;  5EGW A;  1PVJ A;  4FJC A;  3P5V A;  1MEM A;  2FTD A;  2C0Y A;  2R9F A;  4YYS A;  4I04 A;  3PHX A;  2FYE A;  3IUT A;  3O1G A;  4BOP A;  3HWN A;  4OEM A;  2DC8 A;  4PI3 A;  4BOQ A;  3PBH A;  5KO3 A;  2YJ8 A;  2J7Q A;  2PNS A;  2DJG B;  1GCB A;  1QDQ A;  1M6D A;  4CDC B;  4WUR A;  2JTC A;  1BP4 A;  2R9C A;  4PT5 A;  2IPP B;  4QH6 A;  2DC9 A;  1QOL A;  4BS5 A;  2AIM A;  4OVZ A;  1QXP A;  3PSE A;  3KWZ A;  3BB7 A;  3N3G A;  3S3R A;  4D8B A;  3BPF A;  3PHW A;  1AU0 A;  1Y08 A;  2YJC A;  1F2C A;  1JQP A;  3K8U A;  2R9M A;  1DEU A;  2ATO A;  1KHP A;  3AI8 A;  3H8C A;  3TNX A;  1ZCM A;  2ARY A;  3OQC A;  3BC3 A;  4RKX A;  1UKF A;  1Q6K A;  3MJ5 A;  4N8W A;  3KX1 A;  3H8B A;  3V6C A;  4XUI A;  2NQA A;  3PW3 A;  3WXE A;  2E03 A;  2XU1 A;  1CTE A;  2BU3 A;  2PAD A;  4YYQ A;  2ACT A;  4MM3 B;  4BOZ A;  1ITO A;  1MS6 A;  2R9N A;  4ZUX U;  2OUL A;  1CB5 A;  1TLO A;  3U8E A;  4QRX A;  1A6R A;  2AYO A;  2BTW A;  3K24 A;  2HWK A;  3W31 A;  2E02 A;  3IMA A;  2AVW A;  3V6E A;  1PBH A;  1KFX L; 
#chains in the Genus database with same CATH homology
 1PVJ A;  3B21 A;  3PHX A;  2J7Q C;  4BOP A;  3E9S A;  4D8I A;  4OVZ B;  4BOQ A;  4REZ A;  2FE8 A;  5KO3 A;  2J7Q A;  3IFU A;  4RNA A;  4WUR A;  2JTC A;  3BY4 A;  3MP2 A;  4MI7 A;  2Z84 A;  3MTV A;  4PT5 A;  4OW0 A;  4OVZ A;  3TMP A;  5EZS A;  3PSE A;  3BB7 A;  4R3D A;  5EZQ A;  4D8B A;  5E6J A;  3PHW A;  4GUA A;  3O65 A;  3C0R A;  4P16 A;  3RNV A;  3W30 A;  3BBA A;  4RF1 A;  3OQC A;  4BOU A;  4RKX A;  1UKF A;  2JRI A;  3MJ5 A;  2BTW B;  3PHU A;  3PT2 A;  4A5U A;  4M0W A;  4HXD B;  4XZX A;  4IP3 A;  3PRM A;  2UZJ A;  4D8E A;  3ZNH A;  1YZB A;  4IUM A;  4RF0 A;  2BU3 A;  1DKI A;  4MM3 B;  4BOZ A;  5JZE A;  3PRP A;  4ZTB A;  2BTW A;  2DOS A;  2HWK A;  3TRK A;  3W31 A;  4BOS A;  2AGA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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