3MP2A

Crystal structure of transmissible gastroenteritis virus papain-like protease 1
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
211
structure length
211
Chain Sequence
SLPPFKTTNLNGKIILKQGDNNCWINACCYQLQAFDFFNNEAWEKFKKGDVMDFVNLCYAATTLARGHSGDAEYLLELMLNDYSTAKIVLAAKCGCGEKEIVLERAVFKLTPLKESFNYGVCGDCMQVNTCRFLSVEGSGVFVHDILSKQTPEAMFVVKPVMHAVYTGTTQNGHYMVDDIEHGYCVDGMGIKPLKKRCYTSTLFINANVMT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Papain-Like Protease 1 from Transmissible Gastroenteritis Virus: Crystal Structure and Enzymatic Activity toward Viral and Cellular Substrates.
pubmed doi rcsb
molecule tags Hydrolase
source organism Porcine transmissible gastroenteritis coronavirus
molecule keywords Non-structural protein 3
total genus 49
structure length 211
sequence length 211
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 2010-04-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.90 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cathepsin B; Chain A 3mp2A00
4RNAA 4OW0A 4WURA 4RF1A 4RF0A 2FE8A 4R3DA 5E6JA 4M0WA 5KO3A 4MM3B 4OVZA 4REZA 4OVZB 3E9SA 3MP2A 4PT5A 3MJ5A 4P16A
chains in the Genus database with same CATH superfamily
1AECA 3QSDA 5EZQA 1AU4A 3CBJA 2XU4A 3CH2X 2FE8A 4I07A 3HWNA 4R3DA 1BY8A 1EWOA 1SP4B 2DJGB 2G8JA 2HD5A 2BTWA 4N4ZA 5CVNB 5KO3A 1A6RA 2GHUA 1U5IA 1KFUL 3BBAA 3K9MA 4OVZB 4W4UA 4KLBA 2WBFX 4BOSA 1BQIA 3K8UA 1PIPA 4HWYA 4RY2A 1PVJA 2J7QA 1CB5A 2ARYA 1GMYA 1PCIA 4CDCB 4FIPA 5CVOB 2NQGA 3O1GA 2FRQA 2B1MA 4XUIA 1SNKA 3C9EA 1X9YA 5K16A 2DCBA 2OP3A 2B1NA 3OVXA 2PREA 2DCDA 3OVZA 2JQGR 1MIRA 4YYUA 3C0RA 3RVXA 2AU1A 3I06A 4MSXA 2AYOA 2R9CA 3NHEA 4DMYA 3BPFA 4A5UA 4BPVA 4D8BA 1AU3A 1PPNA 3H6SA 3W31A 3RVWA 1U9XA 1ITOA 1AYVA 3P5WA 3MTVA 4YV8A 1O0EA 4W5BA 2OULA 4MI7A 4OVZA 3I3TA 2AS8A 4YVAA 4PT5A 3N3GA 2DC7A 3RNVA 4XZXA 2YJ9A 1NPZA 1FH0A 4BOPA 1KHPA 4FK5A 3V6CA 1PPDA 1PPPA 1PE6A 5A24A 3OQCA 8PCHA 4N8WA 4FJCA 1ATKA 1DF0A 3V6EA 1K3BB 3TRKA 3LXSA 3S3RA 4PP1A 2AVWA 1ICFA 3O0UA 4CDDB 2IPPB 1YVBA 4CDFB 1M6DA 1CTEA 4MM3B 3KWBX 2FRAA 5EZSA 3MP2A 5JH3A 1CQDA 1CJLA 1QOLA 3N4CA 4BSQA 2R9MA 3P5UA 1BGOA 4AXMA 4OW0A 2PNSA 3F5VA 3QT4A 4DMXA 4M0WA 2JRIA 1JQPA 4P6GA 5CHVA 3O65A 1AU2A 3BY4A 4X6JA 3H7DA 2OZ2A 3PDFA 1TLOA 2IBIA 3M99A 2BDZA 3IOQA 5JZEA 3U8EA 3BOWA 4OEMA 7PCKA 2O6XA 1NB5A 3PHUA 1U9VA 3AI8A 1AYUA 4ZUXU 2AYNA 3KW9A 3E9SA 1F2BA 2ACTA 3PHWA 4X6HA 3IMAA 1CV8A 4BS6A 3OISA 2F7DA 1GCBA 1GLOA 2R9NA 4RF0A 2HXZA 1BP4A 2E00A 2G6DA 1Q6KA 3KFQA 1EF7A 2R9FA 1VJVA 1NB3A 2DC9A 3KX1A 4OELA 4REZA 2VHSA 1ME4A 1PADA 1AYWA 3H8BA 1ZCMA 4QRXA 3WXEA 1DKIA 2G7YA 1YZBA 1UKFA 4IUMA 1DEUA 3GCBA 4K7CA 1MEGA 2CB5A 2FQ9A 4XR7A 5EF4A 4QRVA 4G54A 1QDQA 2PADA 1S4VA 1YT7A 4QBBA 1CVZA 3CBKA 3ZNHA 3N3KA 2Y6EA 4BQVA 2FT2A 1VSNA 5CVMA 5E6JA 1F2CA 9PAPA 4PP2E 3BPMA 4BS5A 3BC3A 1QXPA 3BWKA 3MORA 3PT2A 1MS6A 3H8CA 3KSEA 4D8EA 2UZJA 3MJ5A 2BU3A 4CDEB 4YYWA 4D8IA 1NQCA 1NL6A 4P6EA 2XU1A 2NQDB 1F29A 2J7QC 3OF8A 5F02A 3MTNA 3DF0A 4RNAA 1Y08A 2GFOA 4Q8HA 2DC8A 1AIMA 2Z84A 1CS8A 2BDLA 4GUAA 2E03A 2P0RA 2VHFA 3MHSA 2ATOA 4ZTBA 3K24A 1PPOA 1EWMA 1YK8A 2XU5A 4P16A 4WA6A 3IEJA 1ZIVA 3TNXA 4BOUA 3H89A 4YYRA 1STFE 3PRPA 4WURA 5JA7A 2P7UA 3IHPA 4BOQA 3BCNA 2AUZA 4I04A 3PW3A 1U9QX 3BB7A 1NLJA 3D6SA 1MDWA 1MHWA 2DZYA 3E1ZB 1CSBB 1THEA 1MEMA 3PBHA 2H7JA 4I05A 3KWZA 1ME3A 4PI3A 4BOZA 4RF1A 1IWDA 2HWKA 2AGAA 2NQIA 2C0YA 4MZSA 6PADA 2P86A 3MHHA 3PNRA 5FPWA 1POPA 2DJFB 2AIMA 4MZOA 4YYVA 5J94A 2F1GA 3RVVA 2G8EA 2JQFR 1YALA 2JTCA 3F75A 2CIOA 2DOSA 3KKUA 3ZUAA 1XKGA 3B21A 3S3QA 4YYSA 2R9OA 4W5CA 1EWPA 3LFYA 1AU0A 1U9WA 2E02A 3B79A 3PHXA 2DC6A 1EWLA 3WXGA 2FTDA 4YYQA 3TMPA 2E01A 1TL9A 3PRMA 2HHNA 2Y5BA 4CZWA 3CH3X 2FUDA 4RKXA 3P5XA 2PBHA 3IV2A 1KFXL 1PBHA 4HXDB 1YK7A 4PADA 2BTWB 3QJ3A 3IUTA 4AXLA 3P5VA 1TU6A 1KHQA 5EGWA 2DCAA 2FYEA 1QMYA 2YJCA 2YJBA 4N79A 1GECE 1HUCB 4X6IA 3HD3A 3W30A 3PSEA 4QH6A 2DCCA 1CPJA 2YJ2A 3HHAA 3HHIA 5CHTA 3USVA 1Y4HA 4QRGA 3ERVA 2XU3A 5PADA 2NQAA 3WXFA 4Q8GA 1PXVA 4IP3A 1F2AA 2AUXA 2YJ8A 1KXRA 2HH5A 3IFUA 2DZZA 2R6NA 2FO5A 3OF9A
chains in the Genus database with same CATH topology
3TRKA 1YZBA 4BOZA 5EZQA 4RF1A 1UKFA 4IUMA 2HWKA 2AGAA 2FE8A 4R3DA 2BTWA 5KO3A 4MM3B 5EZSA 3BBAA 4OVZB 3MP2A 4BOSA 1PVJA 2J7QA 3ZNHA 2JTCA 4OW0A 2DOSA 5E6JA 4M0WA 2JRIA 3O65A 3B21A 3BY4A 3PT2A 4D8EA 2UZJA 3C0RA 3MJ5A 2BU3A 4D8IA 3PHXA 4A5UA 3TMPA 5JZEA 2J7QC 3PRMA 4D8BA 4RNAA 3W31A 4RKXA 3PHUA 3MTVA 2Z84A 4GUAA 4HXDB 4MI7A 2BTWB 4OVZA 4ZTBA 3E9SA 4PT5A 3RNVA 3PHWA 4P16A 4XZXA 4BOPA 3W30A 3PSEA 4BOUA 3PRPA 4WURA 4RF0A 4BOQA 3OQCA 4REZA 3BB7A 4IP3A 3IFUA 1DKIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RNA A;  4OW0 A;  4WUR A;  4RF1 A;  4RF0 A;  2FE8 A;  4R3D A;  5E6J A;  4M0W A;  5KO3 A;  4MM3 B;  4OVZ A;  4REZ A;  4OVZ B;  3E9S A;  3MP2 A;  4PT5 A;  3MJ5 A;  4P16 A; 
#chains in the Genus database with same CATH topology
 1AEC A;  3QSD A;  5EZQ A;  1AU4 A;  3CBJ A;  2XU4 A;  3CH2 X;  2FE8 A;  4I07 A;  3HWN A;  4R3D A;  1BY8 A;  1EWO A;  1SP4 B;  2DJG B;  2G8J A;  2HD5 A;  2BTW A;  4N4Z A;  5CVN B;  5KO3 A;  1A6R A;  2GHU A;  1U5I A;  1KFU L;  3BBA A;  3K9M A;  4OVZ B;  4W4U A;  4KLB A;  2WBF X;  4BOS A;  1BQI A;  3K8U A;  1PIP A;  4HWY A;  4RY2 A;  1PVJ A;  2J7Q A;  1CB5 A;  2ARY A;  1GMY A;  1PCI A;  4CDC B;  4FIP A;  5CVO B;  2NQG A;  3O1G A;  2FRQ A;  2B1M A;  4XUI A;  1SNK A;  3C9E A;  1X9Y A;  5K16 A;  2DCB A;  2OP3 A;  2B1N A;  3OVX A;  2PRE A;  2DCD A;  3OVZ A;  2JQG R;  1MIR A;  4YYU A;  3C0R A;  3RVX A;  2AU1 A;  3I06 A;  4MSX A;  2AYO A;  2R9C A;  3NHE A;  4DMY A;  3BPF A;  4A5U A;  4BPV A;  4D8B A;  1AU3 A;  1PPN A;  3H6S A;  3W31 A;  3RVW A;  1U9X A;  1ITO A;  1AYV A;  3P5W A;  3MTV A;  4YV8 A;  1O0E A;  4W5B A;  2OUL A;  4MI7 A;  4OVZ A;  3I3T A;  2AS8 A;  4YVA A;  4PT5 A;  3N3G A;  2DC7 A;  3RNV A;  4XZX A;  2YJ9 A;  1NPZ A;  1FH0 A;  4BOP A;  1KHP A;  4FK5 A;  3V6C A;  1PPD A;  1PPP A;  1PE6 A;  5A24 A;  3OQC A;  8PCH A;  4N8W A;  4FJC A;  1ATK A;  1DF0 A;  3V6E A;  1K3B B;  3TRK A;  3LXS A;  3S3R A;  4PP1 A;  2AVW A;  1ICF A;  3O0U A;  4CDD B;  2IPP B;  1YVB A;  4CDF B;  1M6D A;  1CTE A;  4MM3 B;  3KWB X;  2FRA A;  5EZS A;  3MP2 A;  5JH3 A;  1CQD A;  1CJL A;  1QOL A;  3N4C A;  4BSQ A;  2R9M A;  3P5U A;  1BGO A;  4AXM A;  4OW0 A;  2PNS A;  3F5V A;  3QT4 A;  4DMX A;  4M0W A;  2JRI A;  1JQP A;  4P6G A;  5CHV A;  3O65 A;  1AU2 A;  3BY4 A;  4X6J A;  3H7D A;  2OZ2 A;  3PDF A;  1TLO A;  2IBI A;  3M99 A;  2BDZ A;  3IOQ A;  5JZE A;  3U8E A;  3BOW A;  4OEM A;  7PCK A;  2O6X A;  1NB5 A;  3PHU A;  1U9V A;  3AI8 A;  1AYU A;  4ZUX U;  2AYN A;  3KW9 A;  3E9S A;  1F2B A;  2ACT A;  3PHW A;  4X6H A;  3IMA A;  1CV8 A;  4BS6 A;  3OIS A;  2F7D A;  1GCB A;  1GLO A;  2R9N A;  4RF0 A;  2HXZ A;  1BP4 A;  2E00 A;  2G6D A;  1Q6K A;  3KFQ A;  1EF7 A;  2R9F A;  1VJV A;  1NB3 A;  2DC9 A;  3KX1 A;  4OEL A;  4REZ A;  2VHS A;  1ME4 A;  1PAD A;  1AYW A;  3H8B A;  1ZCM A;  4QRX A;  3WXE A;  1DKI A;  2G7Y A;  1YZB A;  1UKF A;  4IUM A;  1DEU A;  3GCB A;  4K7C A;  1MEG A;  2CB5 A;  2FQ9 A;  4XR7 A;  5EF4 A;  4QRV A;  4G54 A;  1QDQ A;  2PAD A;  1S4V A;  1YT7 A;  4QBB A;  1CVZ A;  3CBK A;  3ZNH A;  3N3K A;  2Y6E A;  4BQV A;  2FT2 A;  1VSN A;  5CVM A;  5E6J A;  1F2C A;  9PAP A;  4PP2 E;  3BPM A;  4BS5 A;  3BC3 A;  1QXP A;  3BWK A;  3MOR A;  3PT2 A;  1MS6 A;  3H8C A;  3KSE A;  4D8E A;  2UZJ A;  3MJ5 A;  2BU3 A;  4CDE B;  4YYW A;  4D8I A;  1NQC A;  1NL6 A;  4P6E A;  2XU1 A;  2NQD B;  1F29 A;  2J7Q C;  3OF8 A;  5F02 A;  3MTN A;  3DF0 A;  4RNA A;  1Y08 A;  2GFO A;  4Q8H A;  2DC8 A;  1AIM A;  2Z84 A;  1CS8 A;  2BDL A;  4GUA A;  2E03 A;  2P0R A;  2VHF A;  3MHS A;  2ATO A;  4ZTB A;  3K24 A;  1PPO A;  1EWM A;  1YK8 A;  2XU5 A;  4P16 A;  4WA6 A;  3IEJ A;  1ZIV A;  3TNX A;  4BOU A;  3H89 A;  4YYR A;  1STF E;  3PRP A;  4WUR A;  5JA7 A;  2P7U A;  3IHP A;  4BOQ A;  3BCN A;  2AUZ A;  4I04 A;  3PW3 A;  1U9Q X;  3BB7 A;  1NLJ A;  3D6S A;  1MDW A;  1MHW A;  2DZY A;  3E1Z B;  1CSB B;  1THE A;  1MEM A;  3PBH A;  2H7J A;  4I05 A;  3KWZ A;  1ME3 A;  4PI3 A;  4BOZ A;  4RF1 A;  1IWD A;  2HWK A;  2AGA A;  2NQI A;  2C0Y A;  4MZS A;  6PAD A;  2P86 A;  3MHH A;  3PNR A;  5FPW A;  1POP A;  2DJF B;  2AIM A;  4MZO A;  4YYV A;  5J94 A;  2F1G A;  3RVV A;  2G8E A;  2JQF R;  1YAL A;  2JTC A;  3F75 A;  2CIO A;  2DOS A;  3KKU A;  3ZUA A;  1XKG A;  3B21 A;  3S3Q A;  4YYS A;  2R9O A;  4W5C A;  1EWP A;  3LFY A;  1AU0 A;  1U9W A;  2E02 A;  3B79 A;  3PHX A;  2DC6 A;  1EWL A;  3WXG A;  2FTD A;  4YYQ A;  3TMP A;  2E01 A;  1TL9 A;  3PRM A;  2HHN A;  2Y5B A;  4CZW A;  3CH3 X;  2FUD A;  4RKX A;  3P5X A;  2PBH A;  3IV2 A;  1KFX L;  1PBH A;  4HXD B;  1YK7 A;  4PAD A;  2BTW B;  3QJ3 A;  3IUT A;  4AXL A;  3P5V A;  1TU6 A;  1KHQ A;  5EGW A;  2DCA A;  2FYE A;  1QMY A;  2YJC A;  2YJB A;  4N79 A;  1GEC E;  1HUC B;  4X6I A;  3HD3 A;  3W30 A;  3PSE A;  4QH6 A;  2DCC A;  1CPJ A;  2YJ2 A;  3HHA A;  3HHI A;  5CHT A;  3USV A;  1Y4H A;  4QRG A;  3ERV A;  2XU3 A;  5PAD A;  2NQA A;  3WXF A;  4Q8G A;  1PXV A;  4IP3 A;  1F2A A;  2AUX A;  2YJ8 A;  1KXR A;  2HH5 A;  3IFU A;  2DZZ A;  2R6N A;  2FO5 A;  3OF9 A; 
#chains in the Genus database with same CATH homology
 3TRK A;  1YZB A;  4BOZ A;  5EZQ A;  4RF1 A;  1UKF A;  4IUM A;  2HWK A;  2AGA A;  2FE8 A;  4R3D A;  2BTW A;  5KO3 A;  4MM3 B;  5EZS A;  3BBA A;  4OVZ B;  3MP2 A;  4BOS A;  1PVJ A;  2J7Q A;  3ZNH A;  2JTC A;  4OW0 A;  2DOS A;  5E6J A;  4M0W A;  2JRI A;  3O65 A;  3B21 A;  3BY4 A;  3PT2 A;  4D8E A;  2UZJ A;  3C0R A;  3MJ5 A;  2BU3 A;  4D8I A;  3PHX A;  4A5U A;  3TMP A;  5JZE A;  2J7Q C;  3PRM A;  4D8B A;  4RNA A;  3W31 A;  4RKX A;  3PHU A;  3MTV A;  2Z84 A;  4GUA A;  4HXD B;  4MI7 A;  2BTW B;  4OVZ A;  4ZTB A;  3E9S A;  4PT5 A;  3RNV A;  3PHW A;  4P16 A;  4XZX A;  4BOP A;  3W30 A;  3PSE A;  4BOU A;  3PRP A;  4WUR A;  4RF0 A;  4BOQ A;  3OQC A;  4REZ A;  3BB7 A;  4IP3 A;  3IFU A;  1DKI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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