3PHUA

Otu domain of crimean congo hemorrhagic fever virus
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
184
structure length
183
Chain Sequence
PMDFLRSLDWTQVIAGQYVSNPRFNISDYFEIVRQPGDGNFYHSIAELTMPNKTDHSYHYIKRLTESAARKYYQEEPEARLVGLSLEDYLKRMLSDNEWGSTLEASMLAKEMGITIIIWTVAASDEVEAGIKFGDGDVFTAVNLLHSGQTHFDALRILPQFETDTREALSLMDRVIAVDQLTS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains.
pubmed doi rcsb
molecule tags Hydrolase
source organism Crimean-congo hemorrhagic fever virus strain ibar10200
molecule keywords RNA-directed RNA polymerase L
total genus 58
structure length 183
sequence length 184
chains with identical sequence B
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 2010-11-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02338 OTU OTU-like cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.80 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cathepsin B; Chain A 3phuA01
4BOPA 3PRMA 3PHWA 3PT2A 4HXDB 4BOQA 4BOSA 3ZNHA 4BOZA 4BOUA 5JZEA 3PHUA 3BY4A 3PSEA 3PRPA 3TMPA 3C0RA 3PHXA
chains in the Genus database with same CATH superfamily
1AU4A 5CHTA 4N8WA 3BY4A 3HD3A 3OQCA 4YV8A 1PVJA 1YALA 3E9SA 1PPOA 1CPJA 2FRAA 1EWOA 1AIMA 1YZBA 1PPNA 4DMXA 1MEMA 3LXSA 3OF9A 5CHVA 4OEMA 2WBFX 4Q8GA 2HWKA 5CVMA 8PCHA 3H7DA 2AUXA 4X6IA 1K3BB 1F2AA 1CJLA 1CTEA 2GHUA 3QT4A 1QMYA 2DJGB 3MTVA 3BWKA 3K24A 1DF0A 3OF8A 2OZ2A 3LFYA 3K9MA 3PRMA 2E01A 1BP4A 4XUIA 4QRGA 4RKXA 4G54A 1CS8A 4M0WA 2DC8A 4BS5A 1GECE 4BOUA 1CV8A 2FUDA 2XU5A 3IEJA 2JTCA 4WURA 2IPPB 4Q8HA 2R9FA 2AVWA 2R6NA 4I07A 3TRKA 1EWLA 2R9OA 2ATOA 1ITOA 1YT7A 1BQIA 4XZXA 1NLJA 1EWMA 3CBKA 1EWPA 4CDEB 3IUTA 4REZA 1MHWA 3MTNA 4R3DA 2R9MA 5K16A 3GCBA 1STFE 3H8BA 1AU0A 1YK7A 5JZEA 1VSNA 1PIPA 4BQVA 4BOPA 1QOLA 4X6JA 4AXLA 4CZWA 3RVXA 2FQ9A 2C0YA 4QRXA 3N3GA 2AU1A 1NL6A 4YYSA 1ATKA 2FTDA 4RF0A 3O1GA 4YYVA 3WXEA 3IFUA 1A6RA 2GFOA 3IHPA 4RF1A 2PREA 1BY8A 2YJ9A 5F02A 1NQCA 4QH6A 1MDWA 2J7QC 3PNRA 1EF7A 2XU3A 1U9QX 1TU6A 4MSXA 2Z84A 3BC3A 4GUAA 4ZTBA 2HHNA 5CVNB 2PADA 3I3TA 4K7CA 4ZUXU 4PT5A 3WXFA 1KHPA 2XU4A 5FPWA 3PHXA 2ARYA 3N3KA 2DCDA 3S3RA 1ZCMA 1AYVA 4FIPA 3H8CA 2BTWA 1YVBA 3MHHA 3MHSA 3AI8A 3KW9A 3P5XA 3F75A 4P6EA 2PNSA 3KFQA 3MJ5A 3OVXA 4I04A 3CH2X 1CSBB 4IUMA 1VJVA 3PBHA 2Y5BA 3KSEA 4FJCA 2BU3A 4MM3B 4QBBA 3O65A 1U9VA 4OELA 3C9EA 2AS8A 2Y6EA 4YYQA 5JH3A 2BDLA 2G8JA 1MEGA 3KWZA 5EGWA 2JQFR 3S3QA 5KO3A 4HWYA 4D8BA 4RNAA 5EZQA 2JRIA 3H89A 3IV2A 3KWBX 4YVAA 4HXDB 3PDFA 1KFXL 1FH0A 2G6DA 1X9YA 3PRPA 2P86A 2FE8A 4BPVA 3TNXA 3OISA 1M6DA 1CB5A 4W5CA 1Y08A 1Y4HA 3P5WA 2P7UA 3N4CA 2NQIA 2ACTA 3QSDA 1PPPA 1THEA 1F29A 4P6GA 2DC7A 2AYOA 1AYUA 4OW0A 3V6CA 1CQDA 5PADA 2F7DA 1PBHA 4PADA 3P5VA 4BOSA 1DEUA 4BOZA 1ICFA 2FRQA 1GLOA 2DC9A 3BOWA 1GMYA 1AU3A 1SP4B 5EZSA 1QXPA 1TL9A 2DJFB 2IBIA 3HWNA 1KHQA 3BPFA 9PAPA 2J7QA 3RVVA 2AIMA 1DKIA 4YYWA 2E02A 3C0RA 1F2CA 3PSEA 3BPMA 3I06A 3OVZA 4YYRA 3PW3A 2NQGA 1PPDA 3BCNA 5J94A 1YK8A 4BOQA 1U5IA 1F2BA 3ZNHA 2FT2A 4P16A 4BS6A 3B21A 5A24A 3ZUAA 2NQAA 4MZOA 2YJBA 3CBJA 5JA7A 4N79A 2YJ8A 1AECA 2NQDB 3M99A 2DOSA 2DCAA 1PE6A 2HD5A 4CDCB 2HXZA 2OP3A 2YJCA 3HHAA 1U9XA 3W30A 4PI3A 1PCIA 1MIRA 4WA6A 4PP2E 4OVZA 2O6XA 1IWDA 3F5VA 1CVZA 3QJ3A 1KXRA 2F1GA 3WXGA 2XU1A 3IMAA 3KKUA 3TMPA 4D8EA 2DZYA 3BBAA 3H6SA 4FK5A 4W4UA 3PHUA 1POPA 5CVOB 3V6EA 1AU2A 1TLOA 3NHEA 4A5UA 1JQPA 3CH3X 2DZZA 2H7JA 1AYWA 2JQGR 3ERVA 2PBHA 2DCBA 2CB5A 5E6JA 4KLBA 4W5BA 4PP1A 2BTWB 6PADA 4AXMA 1ME4A 2FYEA 1XKGA 3RNVA 4D8IA 4YYUA 3U8EA 2AGAA 3D6SA 2FO5A 2UZJA 3W31A 1U9WA 7PCKA 1ZIVA 1PADA 5EF4A 2G8EA 2B1NA 4QRVA 4BSQA 3RVWA 3KX1A 3DF0A 3USVA 4CDDB 2DC6A 2DCCA 4MZSA 1NPZA 4IP3A 3HHIA 3IOQA 3O0UA 4OVZB 1BGOA 4X6HA 1MS6A 3BB7A 2VHSA 3K8UA 3PHWA 3PT2A 1KFUL 1PXVA 4N4ZA 2BDZA 1S4VA 2HH5A 3P5UA 4DMYA 1ME3A 1O0EA 3B79A 3MP2A 4I05A 2VHFA 2AYNA 1UKFA 2P0RA 1GCBA 2YJ2A 2E03A 2G7YA 1HUCB 1SNKA 2B1MA 4MI7A 1NB5A 2R9NA 2CIOA 1Q6KA 4XR7A 3MORA 2E00A 4CDFB 2OULA 1NB3A 1QDQA 4RY2A 3E1ZB 2AUZA 2R9CA
chains in the Genus database with same CATH topology
2FE8A 4OVZA 3BY4A 3OQCA 1PVJA 3E9SA 4RF0A 3TMPA 4D8EA 3BBAA 3IFUA 3PHUA 4RF1A 1YZBA 2J7QC 4A5UA 4OW0A 2Z84A 4GUAA 4ZTBA 2HWKA 5E6JA 4BOSA 4PT5A 2BTWB 4BOZA 3PHXA 3RNVA 4D8IA 2AGAA 2UZJA 3W31A 3MTVA 2BTWA 5EZSA 3PRMA 2J7QA 4RKXA 1DKIA 4IP3A 3MJ5A 4M0WA 4IUMA 4BOUA 3C0RA 4OVZB 3BB7A 2JTCA 2BU3A 4MM3B 3PSEA 4WURA 3O65A 3PHWA 3PT2A 3TRKA 4BOQA 3ZNHA 4XZXA 4P16A 3B21A 3MP2A 5KO3A 4REZA 4D8BA 1UKFA 4RNAA 5EZQA 4R3DA 2JRIA 4MI7A 2DOSA 4HXDB 3W30A 5JZEA 3PRPA 4BOPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BOP A;  3PRM A;  3PHW A;  3PT2 A;  4HXD B;  4BOQ A;  4BOS A;  3ZNH A;  4BOZ A;  4BOU A;  5JZE A;  3PHU A;  3BY4 A;  3PSE A;  3PRP A;  3TMP A;  3C0R A;  3PHX A; 
#chains in the Genus database with same CATH topology
 1AU4 A;  5CHT A;  4N8W A;  3BY4 A;  3HD3 A;  3OQC A;  4YV8 A;  1PVJ A;  1YAL A;  3E9S A;  1PPO A;  1CPJ A;  2FRA A;  1EWO A;  1AIM A;  1YZB A;  1PPN A;  4DMX A;  1MEM A;  3LXS A;  3OF9 A;  5CHV A;  4OEM A;  2WBF X;  4Q8G A;  2HWK A;  5CVM A;  8PCH A;  3H7D A;  2AUX A;  4X6I A;  1K3B B;  1F2A A;  1CJL A;  1CTE A;  2GHU A;  3QT4 A;  1QMY A;  2DJG B;  3MTV A;  3BWK A;  3K24 A;  1DF0 A;  3OF8 A;  2OZ2 A;  3LFY A;  3K9M A;  3PRM A;  2E01 A;  1BP4 A;  4XUI A;  4QRG A;  4RKX A;  4G54 A;  1CS8 A;  4M0W A;  2DC8 A;  4BS5 A;  1GEC E;  4BOU A;  1CV8 A;  2FUD A;  2XU5 A;  3IEJ A;  2JTC A;  4WUR A;  2IPP B;  4Q8H A;  2R9F A;  2AVW A;  2R6N A;  4I07 A;  3TRK A;  1EWL A;  2R9O A;  2ATO A;  1ITO A;  1YT7 A;  1BQI A;  4XZX A;  1NLJ A;  1EWM A;  3CBK A;  1EWP A;  4CDE B;  3IUT A;  4REZ A;  1MHW A;  3MTN A;  4R3D A;  2R9M A;  5K16 A;  3GCB A;  1STF E;  3H8B A;  1AU0 A;  1YK7 A;  5JZE A;  1VSN A;  1PIP A;  4BQV A;  4BOP A;  1QOL A;  4X6J A;  4AXL A;  4CZW A;  3RVX A;  2FQ9 A;  2C0Y A;  4QRX A;  3N3G A;  2AU1 A;  1NL6 A;  4YYS A;  1ATK A;  2FTD A;  4RF0 A;  3O1G A;  4YYV A;  3WXE A;  3IFU A;  1A6R A;  2GFO A;  3IHP A;  4RF1 A;  2PRE A;  1BY8 A;  2YJ9 A;  5F02 A;  1NQC A;  4QH6 A;  1MDW A;  2J7Q C;  3PNR A;  1EF7 A;  2XU3 A;  1U9Q X;  1TU6 A;  4MSX A;  2Z84 A;  3BC3 A;  4GUA A;  4ZTB A;  2HHN A;  5CVN B;  2PAD A;  3I3T A;  4K7C A;  4ZUX U;  4PT5 A;  3WXF A;  1KHP A;  2XU4 A;  5FPW A;  3PHX A;  2ARY A;  3N3K A;  2DCD A;  3S3R A;  1ZCM A;  1AYV A;  4FIP A;  3H8C A;  2BTW A;  1YVB A;  3MHH A;  3MHS A;  3AI8 A;  3KW9 A;  3P5X A;  3F75 A;  4P6E A;  2PNS A;  3KFQ A;  3MJ5 A;  3OVX A;  4I04 A;  3CH2 X;  1CSB B;  4IUM A;  1VJV A;  3PBH A;  2Y5B A;  3KSE A;  4FJC A;  2BU3 A;  4MM3 B;  4QBB A;  3O65 A;  1U9V A;  4OEL A;  3C9E A;  2AS8 A;  2Y6E A;  4YYQ A;  5JH3 A;  2BDL A;  2G8J A;  1MEG A;  3KWZ A;  5EGW A;  2JQF R;  3S3Q A;  5KO3 A;  4HWY A;  4D8B A;  4RNA A;  5EZQ A;  2JRI A;  3H89 A;  3IV2 A;  3KWB X;  4YVA A;  4HXD B;  3PDF A;  1KFX L;  1FH0 A;  2G6D A;  1X9Y A;  3PRP A;  2P86 A;  2FE8 A;  4BPV A;  3TNX A;  3OIS A;  1M6D A;  1CB5 A;  4W5C A;  1Y08 A;  1Y4H A;  3P5W A;  2P7U A;  3N4C A;  2NQI A;  2ACT A;  3QSD A;  1PPP A;  1THE A;  1F29 A;  4P6G A;  2DC7 A;  2AYO A;  1AYU A;  4OW0 A;  3V6C A;  1CQD A;  5PAD A;  2F7D A;  1PBH A;  4PAD A;  3P5V A;  4BOS A;  1DEU A;  4BOZ A;  1ICF A;  2FRQ A;  1GLO A;  2DC9 A;  3BOW A;  1GMY A;  1AU3 A;  1SP4 B;  5EZS A;  1QXP A;  1TL9 A;  2DJF B;  2IBI A;  3HWN A;  1KHQ A;  3BPF A;  9PAP A;  2J7Q A;  3RVV A;  2AIM A;  1DKI A;  4YYW A;  2E02 A;  3C0R A;  1F2C A;  3PSE A;  3BPM A;  3I06 A;  3OVZ A;  4YYR A;  3PW3 A;  2NQG A;  1PPD A;  3BCN A;  5J94 A;  1YK8 A;  4BOQ A;  1U5I A;  1F2B A;  3ZNH A;  2FT2 A;  4P16 A;  4BS6 A;  3B21 A;  5A24 A;  3ZUA A;  2NQA A;  4MZO A;  2YJB A;  3CBJ A;  5JA7 A;  4N79 A;  2YJ8 A;  1AEC A;  2NQD B;  3M99 A;  2DOS A;  2DCA A;  1PE6 A;  2HD5 A;  4CDC B;  2HXZ A;  2OP3 A;  2YJC A;  3HHA A;  1U9X A;  3W30 A;  4PI3 A;  1PCI A;  1MIR A;  4WA6 A;  4PP2 E;  4OVZ A;  2O6X A;  1IWD A;  3F5V A;  1CVZ A;  3QJ3 A;  1KXR A;  2F1G A;  3WXG A;  2XU1 A;  3IMA A;  3KKU A;  3TMP A;  4D8E A;  2DZY A;  3BBA A;  3H6S A;  4FK5 A;  4W4U A;  3PHU A;  1POP A;  5CVO B;  3V6E A;  1AU2 A;  1TLO A;  3NHE A;  4A5U A;  1JQP A;  3CH3 X;  2DZZ A;  2H7J A;  1AYW A;  2JQG R;  3ERV A;  2PBH A;  2DCB A;  2CB5 A;  5E6J A;  4KLB A;  4W5B A;  4PP1 A;  2BTW B;  6PAD A;  4AXM A;  1ME4 A;  2FYE A;  1XKG A;  3RNV A;  4D8I A;  4YYU A;  3U8E A;  2AGA A;  3D6S A;  2FO5 A;  2UZJ A;  3W31 A;  1U9W A;  7PCK A;  1ZIV A;  1PAD A;  5EF4 A;  2G8E A;  2B1N A;  4QRV A;  4BSQ A;  3RVW A;  3KX1 A;  3DF0 A;  3USV A;  4CDD B;  2DC6 A;  2DCC A;  4MZS A;  1NPZ A;  4IP3 A;  3HHI A;  3IOQ A;  3O0U A;  4OVZ B;  1BGO A;  4X6H A;  1MS6 A;  3BB7 A;  2VHS A;  3K8U A;  3PHW A;  3PT2 A;  1KFU L;  1PXV A;  4N4Z A;  2BDZ A;  1S4V A;  2HH5 A;  3P5U A;  4DMY A;  1ME3 A;  1O0E A;  3B79 A;  3MP2 A;  4I05 A;  2VHF A;  2AYN A;  1UKF A;  2P0R A;  1GCB A;  2YJ2 A;  2E03 A;  2G7Y A;  1HUC B;  1SNK A;  2B1M A;  4MI7 A;  1NB5 A;  2R9N A;  2CIO A;  1Q6K A;  4XR7 A;  3MOR A;  2E00 A;  4CDF B;  2OUL A;  1NB3 A;  1QDQ A;  4RY2 A;  3E1Z B;  2AUZ A;  2R9C A; 
#chains in the Genus database with same CATH homology
 2FE8 A;  4OVZ A;  3BY4 A;  3OQC A;  1PVJ A;  3E9S A;  4RF0 A;  3TMP A;  4D8E A;  3BBA A;  3IFU A;  3PHU A;  4RF1 A;  1YZB A;  2J7Q C;  4A5U A;  4OW0 A;  2Z84 A;  4GUA A;  4ZTB A;  2HWK A;  5E6J A;  4BOS A;  4PT5 A;  2BTW B;  4BOZ A;  3PHX A;  3RNV A;  4D8I A;  2AGA A;  2UZJ A;  3W31 A;  3MTV A;  2BTW A;  5EZS A;  3PRM A;  2J7Q A;  4RKX A;  1DKI A;  4IP3 A;  3MJ5 A;  4M0W A;  4IUM A;  4BOU A;  3C0R A;  4OVZ B;  3BB7 A;  2JTC A;  2BU3 A;  4MM3 B;  3PSE A;  4WUR A;  3O65 A;  3PHW A;  3PT2 A;  3TRK A;  4BOQ A;  3ZNH A;  4XZX A;  4P16 A;  3B21 A;  3MP2 A;  5KO3 A;  4REZ A;  4D8B A;  1UKF A;  4RNA A;  5EZQ A;  4R3D A;  2JRI A;  4MI7 A;  2DOS A;  4HXD B;  3W30 A;  5JZE A;  3PRP A;  4BOP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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