3PHWA

Otu domain of crimean congo hemorrhagic fever virus in complex with ubiquitin
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
160
structure length
156
Chain Sequence
FLRSLDWTQVIAGQYVSNPRFNISDYFEIVRQPGDGNCFYHSIAELTMPNKTDHSYHYIKRLTESAARKYYQEEPEARLVGLSLEDYLKRMLSDNEWGSTLEASMLAKEMGITIIIWTVEVEAGIKFGDGDVFTAVNLLHSGQTHFDALRILPQFE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains.
pubmed doi rcsb
molecule tags Hydrolase/ribosomal protein
source organism Crimean-congo hemorrhagic fever virus strain ibar10200
molecule keywords RNA-directed RNA polymerase L
total genus 48
structure length 156
sequence length 160
chains with identical sequence C, E, G
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 2010-11-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02338 OTU OTU-like cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.80 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cathepsin B; Chain A 3phwA00
3PHXA 3C0RA 3BY4A 4HXDB 4BOPA 5JZEA 3PHUA 3PT2A 3PRPA 4BOSA 4BOQA 4BOUA 3PSEA 3PHWA 4BOZA 3ZNHA 3PRMA 3TMPA
chains in the Genus database with same CATH superfamily
3GCBA 3WXGA 3RNVA 1DKIA 3BCNA 5JH3A 3IHPA 4YYUA 1PXVA 3IOQA 2GHUA 1GCBA 2AIMA 4CDEB 4CDFB 3KWZA 4CDDB 4RF1A 3IEJA 1GMYA 1PE6A 3PHXA 3WXEA 3OISA 4PADA 1PPDA 2XU4A 5FPWA 3V6EA 2DOSA 4ZUXU 2FRQA 2Z84A 3BOWA 2R9OA 3TRKA 1Y08A 3I3TA 3ERVA 4MZSA 1PBHA 4P16A 3USVA 1TL9A 2NQIA 3WXFA 3F75A 4OW0A 3V6CA 1AIMA 2JRIA 4QRVA 1YZBA 4BOSA 4N4ZA 8PCHA 2DC8A 3W31A 3IFUA 2AS8A 2CIOA 2XU1A 2WBFX 4QH6A 2R9NA 3PNRA 3PHUA 1QOLA 4W4UA 3BPMA 1AECA 2DZZA 3S3RA 3OF8A 1PPNA 2FUDA 3QJ3A 5F02A 4QBBA 2CB5A 2FRAA 4BQVA 4YYQA 2R9MA 3DF0A 3RVWA 1ME4A 5CHTA 3QSDA 1MIRA 3CH3X 1SNKA 3BWKA 4CDCB 2PBHA 1PVJA 1NPZA 4Q8HA 1AYVA 3MHSA 4I04A 4BOPA 2HXZA 1K3BB 5JA7A 4DMYA 2IBIA 3KWBX 2AUZA 2VHFA 1BY8A 1STFE 2YJ9A 2BU3A 4P6EA 3N4CA 3D6SA 4P6GA 2Y6EA 1PADA 1IWDA 1MEMA 2PREA 4N79A 1U9QX 2FE8A 4D8BA 3MP2A 1PCIA 3MHHA 2AVWA 4HWYA 3NHEA 2BTWA 4OEMA 2BDZA 3KKUA 1EF7A 4X6HA 1UKFA 4PP1A 4I05A 4IP3A 1DF0A 1POPA 1GLOA 1SP4B 4WA6A 1AU4A 2PADA 2FTDA 3CBKA 3KSEA 5JZEA 5KO3A 1S4VA 3OVXA 2G6DA 4W5CA 3OQCA 3OVZA 2DC6A 5CVMA 2OP3A 1CTEA 3IV2A 4FK5A 1QMYA 4MSXA 1CVZA 4QRXA 1ME3A 4DMXA 3O1GA 2P0RA 1VSNA 4RNAA 2NQGA 4BPVA 3ZNHA 3E9SA 4YVAA 4OVZB 3O65A 4M0WA 4PP2E 1BGOA 3BBAA 2J7QC 3HWNA 3U8EA 1PPPA 2YJ8A 3BB7A 3H8BA 3B21A 3CH2X 3KFQA 1KHQA 3LXSA 2AGAA 2F1GA 2FQ9A 4D8EA 3E1ZB 1NLJA 3PDFA 1NQCA 3K24A 4BOZA 1EWPA 1EWMA 1GECE 4BSQA 3PRPA 5EZSA 4QRGA 2YJ2A 2H7JA 3IMAA 2G7YA 1JQPA 3M99A 4Q8GA 4D8IA 1MEGA 2E00A 1XKGA 3P5UA 1ATKA 1AU3A 2DZYA 2G8EA 3CBJA 1AYWA 3O0UA 1U9VA 1KFUL 1EWLA 2PNSA 4KLBA 2DC9A 3RVVA 4A5UA 2NQAA 3QT4A 4K7CA 3C9EA 3H8CA 1O0EA 2P7UA 3P5WA 2AYNA 1PPOA 3K9MA 1YK8A 2ARYA 3TNXA 1CB5A 2AU1A 5CVNB 2AYOA 2J7QA 3MTNA 1YALA 1Y4HA 4BS6A 1M6DA 4MM3B 1F2BA 5PADA 1CV8A 4RY2A 5EF4A 4OELA 5K16A 7PCKA 4BS5A 1U5IA 1TU6A 1F29A 1NB3A 1THEA 2HHNA 4RKXA 2R9FA 2YJBA 1AU2A 1YK7A 4YYWA 1PIPA 2B1MA 1FH0A 2R9CA 4GUAA 1QXPA 5EZQA 2JQGR 2C0YA 1CS8A 2IPPB 3MTVA 4FIPA 3P5XA 1NB5A 3H89A 4MZOA 3C0RA 2E02A 4W5BA 3HD3A 3MJ5A 2B1NA 5CHVA 4ZTBA 2FO5A 4X6JA 3ZUAA 4HXDB 3BC3A 4IUMA 1QDQA 4BOUA 1ITOA 3B79A 2ATOA 2DCBA 1U9XA 2XU3A 2F7DA 2BDLA 4YV8A 4YYSA 3BY4A 4PI3A 5CVOB 1CQDA 4REZA 4AXLA 4YYRA 3HHIA 3PHWA 3IUTA 4MI7A 4XR7A 2DCCA 4R3DA 1KHPA 3AI8A 2OZ2A 2JQFR 4X6IA 3K8UA 1MDWA 2E03A 2GFOA 5A24A 2AUXA 2UZJA 3N3GA 3N3KA 2HWKA 2YJCA 2BTWB 1ICFA 4XZXA 1TLOA 2FT2A 2E01A 2VHSA 1AU0A 3RVXA 1KXRA 1CJLA 1DEUA 4RF0A 1YVBA 3PW3A 4N8WA 5E6JA 4BOQA 2DJFB 2R6NA 4G54A 2Y5BA 1NL6A 1Q6KA 4XUIA 2O6XA 1MS6A 1CSBB 3PRMA 2XU5A 3S3QA 1HUCB 3KX1A 1A6RA 5EGWA 2HH5A 5J94A 1ZCMA 3H6SA 3H7DA 1F2CA 1F2AA 3P5VA 2HD5A 2DCAA 2G8JA 3F5VA 1AYUA 2P86A 4OVZA 1BQIA 2ACTA 4CZWA 2JTCA 3OF9A 1CPJA 2NQDB 1BP4A 6PADA 3MORA 3I06A 1VJVA 2OULA 2FYEA 2DCDA 2DC7A 1KFXL 3LFYA 1X9YA 4PT5A 3PT2A 2DJGB 1EWOA 4WURA 9PAPA 3HHAA 1U9WA 1YT7A 3PSEA 4YYVA 4I07A 3KW9A 3W30A 3PBHA 3BPFA 4FJCA 4AXMA 1ZIVA 3TMPA 1MHWA
chains in the Genus database with same CATH topology
3BY4A 4REZA 3RNVA 1DKIA 3PHWA 4MI7A 4R3DA 4D8IA 2FE8A 4D8BA 4RF1A 3MP2A 3PHXA 2UZJA 2DOSA 2HWKA 4A5UA 2BTWA 2BTWB 2Z84A 4XZXA 3TRKA 1UKFA 4IP3A 4RF0A 4P16A 5E6JA 4BOQA 2J7QA 5KO3A 5JZEA 4OW0A 4MM3B 2JRIA 1YZBA 3PRMA 4BOSA 3OQCA 3W31A 3IFUA 4RKXA 4RNAA 3PHUA 3ZNHA 3E9SA 4OVZA 4OVZB 2JTCA 3O65A 4GUAA 4M0WA 5EZQA 3BBAA 2J7QC 3MTVA 3BB7A 3C0RA 4PT5A 3B21A 3PT2A 3MJ5A 4ZTBA 4WURA 1PVJA 4HXDB 4IUMA 2AGAA 4BOUA 3PSEA 4D8EA 4BOPA 3W30A 4BOZA 3PRPA 5EZSA 2BU3A 3TMPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PHX A;  3C0R A;  3BY4 A;  4HXD B;  4BOP A;  5JZE A;  3PHU A;  3PT2 A;  3PRP A;  4BOS A;  4BOQ A;  4BOU A;  3PSE A;  3PHW A;  4BOZ A;  3ZNH A;  3PRM A;  3TMP A; 
#chains in the Genus database with same CATH topology
 3GCB A;  3WXG A;  3RNV A;  1DKI A;  3BCN A;  5JH3 A;  3IHP A;  4YYU A;  1PXV A;  3IOQ A;  2GHU A;  1GCB A;  2AIM A;  4CDE B;  4CDF B;  3KWZ A;  4CDD B;  4RF1 A;  3IEJ A;  1GMY A;  1PE6 A;  3PHX A;  3WXE A;  3OIS A;  4PAD A;  1PPD A;  2XU4 A;  5FPW A;  3V6E A;  2DOS A;  4ZUX U;  2FRQ A;  2Z84 A;  3BOW A;  2R9O A;  3TRK A;  1Y08 A;  3I3T A;  3ERV A;  4MZS A;  1PBH A;  4P16 A;  3USV A;  1TL9 A;  2NQI A;  3WXF A;  3F75 A;  4OW0 A;  3V6C A;  1AIM A;  2JRI A;  4QRV A;  1YZB A;  4BOS A;  4N4Z A;  8PCH A;  2DC8 A;  3W31 A;  3IFU A;  2AS8 A;  2CIO A;  2XU1 A;  2WBF X;  4QH6 A;  2R9N A;  3PNR A;  3PHU A;  1QOL A;  4W4U A;  3BPM A;  1AEC A;  2DZZ A;  3S3R A;  3OF8 A;  1PPN A;  2FUD A;  3QJ3 A;  5F02 A;  4QBB A;  2CB5 A;  2FRA A;  4BQV A;  4YYQ A;  2R9M A;  3DF0 A;  3RVW A;  1ME4 A;  5CHT A;  3QSD A;  1MIR A;  3CH3 X;  1SNK A;  3BWK A;  4CDC B;  2PBH A;  1PVJ A;  1NPZ A;  4Q8H A;  1AYV A;  3MHS A;  4I04 A;  4BOP A;  2HXZ A;  1K3B B;  5JA7 A;  4DMY A;  2IBI A;  3KWB X;  2AUZ A;  2VHF A;  1BY8 A;  1STF E;  2YJ9 A;  2BU3 A;  4P6E A;  3N4C A;  3D6S A;  4P6G A;  2Y6E A;  1PAD A;  1IWD A;  1MEM A;  2PRE A;  4N79 A;  1U9Q X;  2FE8 A;  4D8B A;  3MP2 A;  1PCI A;  3MHH A;  2AVW A;  4HWY A;  3NHE A;  2BTW A;  4OEM A;  2BDZ A;  3KKU A;  1EF7 A;  4X6H A;  1UKF A;  4PP1 A;  4I05 A;  4IP3 A;  1DF0 A;  1POP A;  1GLO A;  1SP4 B;  4WA6 A;  1AU4 A;  2PAD A;  2FTD A;  3CBK A;  3KSE A;  5JZE A;  5KO3 A;  1S4V A;  3OVX A;  2G6D A;  4W5C A;  3OQC A;  3OVZ A;  2DC6 A;  5CVM A;  2OP3 A;  1CTE A;  3IV2 A;  4FK5 A;  1QMY A;  4MSX A;  1CVZ A;  4QRX A;  1ME3 A;  4DMX A;  3O1G A;  2P0R A;  1VSN A;  4RNA A;  2NQG A;  4BPV A;  3ZNH A;  3E9S A;  4YVA A;  4OVZ B;  3O65 A;  4M0W A;  4PP2 E;  1BGO A;  3BBA A;  2J7Q C;  3HWN A;  3U8E A;  1PPP A;  2YJ8 A;  3BB7 A;  3H8B A;  3B21 A;  3CH2 X;  3KFQ A;  1KHQ A;  3LXS A;  2AGA A;  2F1G A;  2FQ9 A;  4D8E A;  3E1Z B;  1NLJ A;  3PDF A;  1NQC A;  3K24 A;  4BOZ A;  1EWP A;  1EWM A;  1GEC E;  4BSQ A;  3PRP A;  5EZS A;  4QRG A;  2YJ2 A;  2H7J A;  3IMA A;  2G7Y A;  1JQP A;  3M99 A;  4Q8G A;  4D8I A;  1MEG A;  2E00 A;  1XKG A;  3P5U A;  1ATK A;  1AU3 A;  2DZY A;  2G8E A;  3CBJ A;  1AYW A;  3O0U A;  1U9V A;  1KFU L;  1EWL A;  2PNS A;  4KLB A;  2DC9 A;  3RVV A;  4A5U A;  2NQA A;  3QT4 A;  4K7C A;  3C9E A;  3H8C A;  1O0E A;  2P7U A;  3P5W A;  2AYN A;  1PPO A;  3K9M A;  1YK8 A;  2ARY A;  3TNX A;  1CB5 A;  2AU1 A;  5CVN B;  2AYO A;  2J7Q A;  3MTN A;  1YAL A;  1Y4H A;  4BS6 A;  1M6D A;  4MM3 B;  1F2B A;  5PAD A;  1CV8 A;  4RY2 A;  5EF4 A;  4OEL A;  5K16 A;  7PCK A;  4BS5 A;  1U5I A;  1TU6 A;  1F29 A;  1NB3 A;  1THE A;  2HHN A;  4RKX A;  2R9F A;  2YJB A;  1AU2 A;  1YK7 A;  4YYW A;  1PIP A;  2B1M A;  1FH0 A;  2R9C A;  4GUA A;  1QXP A;  5EZQ A;  2JQG R;  2C0Y A;  1CS8 A;  2IPP B;  3MTV A;  4FIP A;  3P5X A;  1NB5 A;  3H89 A;  4MZO A;  3C0R A;  2E02 A;  4W5B A;  3HD3 A;  3MJ5 A;  2B1N A;  5CHV A;  4ZTB A;  2FO5 A;  4X6J A;  3ZUA A;  4HXD B;  3BC3 A;  4IUM A;  1QDQ A;  4BOU A;  1ITO A;  3B79 A;  2ATO A;  2DCB A;  1U9X A;  2XU3 A;  2F7D A;  2BDL A;  4YV8 A;  4YYS A;  3BY4 A;  4PI3 A;  5CVO B;  1CQD A;  4REZ A;  4AXL A;  4YYR A;  3HHI A;  3PHW A;  3IUT A;  4MI7 A;  4XR7 A;  2DCC A;  4R3D A;  1KHP A;  3AI8 A;  2OZ2 A;  2JQF R;  4X6I A;  3K8U A;  1MDW A;  2E03 A;  2GFO A;  5A24 A;  2AUX A;  2UZJ A;  3N3G A;  3N3K A;  2HWK A;  2YJC A;  2BTW B;  1ICF A;  4XZX A;  1TLO A;  2FT2 A;  2E01 A;  2VHS A;  1AU0 A;  3RVX A;  1KXR A;  1CJL A;  1DEU A;  4RF0 A;  1YVB A;  3PW3 A;  4N8W A;  5E6J A;  4BOQ A;  2DJF B;  2R6N A;  4G54 A;  2Y5B A;  1NL6 A;  1Q6K A;  4XUI A;  2O6X A;  1MS6 A;  1CSB B;  3PRM A;  2XU5 A;  3S3Q A;  1HUC B;  3KX1 A;  1A6R A;  5EGW A;  2HH5 A;  5J94 A;  1ZCM A;  3H6S A;  3H7D A;  1F2C A;  1F2A A;  3P5V A;  2HD5 A;  2DCA A;  2G8J A;  3F5V A;  1AYU A;  2P86 A;  4OVZ A;  1BQI A;  2ACT A;  4CZW A;  2JTC A;  3OF9 A;  1CPJ A;  2NQD B;  1BP4 A;  6PAD A;  3MOR A;  3I06 A;  1VJV A;  2OUL A;  2FYE A;  2DCD A;  2DC7 A;  1KFX L;  3LFY A;  1X9Y A;  4PT5 A;  3PT2 A;  2DJG B;  1EWO A;  4WUR A;  9PAP A;  3HHA A;  1U9W A;  1YT7 A;  3PSE A;  4YYV A;  4I07 A;  3KW9 A;  3W30 A;  3PBH A;  3BPF A;  4FJC A;  4AXM A;  1ZIV A;  3TMP A;  1MHW A; 
#chains in the Genus database with same CATH homology
 3BY4 A;  4REZ A;  3RNV A;  1DKI A;  3PHW A;  4MI7 A;  4R3D A;  4D8I A;  2FE8 A;  4D8B A;  4RF1 A;  3MP2 A;  3PHX A;  2UZJ A;  2DOS A;  2HWK A;  4A5U A;  2BTW A;  2BTW B;  2Z84 A;  4XZX A;  3TRK A;  1UKF A;  4IP3 A;  4RF0 A;  4P16 A;  5E6J A;  4BOQ A;  2J7Q A;  5KO3 A;  5JZE A;  4OW0 A;  4MM3 B;  2JRI A;  1YZB A;  3PRM A;  4BOS A;  3OQC A;  3W31 A;  3IFU A;  4RKX A;  4RNA A;  3PHU A;  3ZNH A;  3E9S A;  4OVZ A;  4OVZ B;  2JTC A;  3O65 A;  4GUA A;  4M0W A;  5EZQ A;  3BBA A;  2J7Q C;  3MTV A;  3BB7 A;  3C0R A;  4PT5 A;  3B21 A;  3PT2 A;  3MJ5 A;  4ZTB A;  4WUR A;  1PVJ A;  4HXD B;  4IUM A;  2AGA A;  4BOU A;  3PSE A;  4D8E A;  4BOP A;  3W30 A;  4BOZ A;  3PRP A;  5EZS A;  2BU3 A;  3TMP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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