3PT2A

Structure of a viral otu domain protease bound to ubiquitin
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
164
structure length
164
Chain Sequence
PGMDFLRSLDWTQVIAGQYVSNPRFNISDYFEIVRQPGDGNCFYHSIAELTMPNKTDHSYHYIKRLTESAARKYYQEEPEARLVGLSLEDYLKRMLSDNEWGSTLEASMLAKEMGITIIIWTVAASDEVEAGIKFGDGDVFTAVNLLHSGQTHFDALRILPQFE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease.
pubmed doi rcsb
molecule tags Hydrolase/protein binding
source organism Crimean-congo hemorrhagic fever virus
molecule keywords RNA polymerase
total genus 46
structure length 164
sequence length 164
ec nomenclature
pdb deposition date 2010-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02338 OTU OTU-like cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.80 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cathepsin B; Chain A 3pt2A00
3PT2A 3C0RA 3PRMA 3PRPA 3TMPA 4BOSA 4BOPA 3ZNHA 3PHUA 4BOUA 3PHWA 3PHXA 3BY4A 3PSEA 4BOZA 4BOQA 5JZEA 4HXDB
chains in the Genus database with same CATH superfamily
4P6GA 3WXGA 3O1GA 1AU4A 1O0EA 3HD3A 1AU0A 2F7DA 4BOQA 4W5BA 3OF8A 2E02A 3S3QA 1CTEA 2OULA 1YK7A 4REZA 4CDCB 1TLOA 1YT7A 3K9MA 1CQDA 5EZSA 2R9MA 3TRKA 1VJVA 1QDQA 2C0YA 2XU3A 2P86A 1VSNA 3B79A 3BCNA 1MEMA 2GFOA 3C9EA 4OVZB 2VHSA 2FYEA 2HH5A 2JQFR 1QXPA 1AU2A 4MZSA 5EGWA 4OEMA 1NL6A 1U9QX 3BPFA 1PE6A 5KO3A 5CVOB 3H6SA 1GMYA 1POPA 4N79A 1MHWA 2BTWB 1ME3A 1AIMA 4N8WA 2E03A 1F29A 2OP3A 1X9YA 1JQPA 1U9WA 2H7JA 4P16A 1MDWA 4QRXA 3MP2A 3HHIA 1NPZA 3KW9A 2R9CA 4PADA 1BQIA 1BGOA 2AUZA 1AYWA 2JRIA 3D6SA 2HHNA 5FPWA 2YJBA 1STFE 2BTWA 1AYVA 1ICFA 3KWZA 1KHPA 1ME4A 1MEGA 1ITOA 2G7YA 4P6EA 1KHQA 1TU6A 3E1ZB 5JA7A 3MJ5A 1ZIVA 2DZYA 1F2CA 1BY8A 1M6DA 2DOSA 2DCDA 2YJ9A 4WURA 3DF0A 2DJGB 3B21A 4XZXA 2ACTA 2E01A 3KSEA 2AUXA 1MS6A 2YJ2A 4YYRA 2HD5A 3H7DA 4D8IA 3WXEA 3H89A 3P5VA 3BC3A 3KWBX 4N4ZA 4YVAA 4X6JA 2P0RA 1U5IA 1KXRA 2NQIA 2DCBA 4PI3A 3HWNA 1MIRA 4HXDB 2DCAA 2DCCA 3PT2A 3TNXA 5F02A 3N4CA 1HUCB 3MTVA 4PP1A 4XR7A 1SNKA 3TMPA 3MTNA 2B1MA 4BS6A 4FK5A 3AI8A 2Y6EA 2FUDA 4IUMA 3IOQA 4CDEB 3PDFA 3PHXA 4MZOA 3CH3X 4WA6A 2PREA 1K3BB 4CZWA 1SP4B 3V6CA 3PHWA 5EZQA 4D8EA 1PPOA 1PVJA 2DC6A 2WBFX 3F75A 8PCHA 3K8UA 3P5XA 2XU4A 2BU3A 3CH2X 1EF7A 1U9XA 2YJCA 4BS5A 3KKUA 2J7QA 1NB5A 4BOUA 1CV8A 2JTCA 4X6HA 1QOLA 2VHFA 2AYNA 3PNRA 3IMAA 2R9FA 3F5VA 1GECE 3GCBA 4DMYA 1IWDA 2IPPB 4BPVA 2PBHA 3MHHA 1PCIA 4D8BA 2FRQA 4PT5A 4RF0A 1EWLA 4YYWA 4AXLA 3IEJA 1Q6KA 2FQ9A 1AU3A 2GHUA 3C0RA 3IFUA 3RVXA 4X6IA 2P7UA 3IV2A 9PAPA 2YJ8A 3BBAA 1AYUA 2NQGA 3BY4A 3I06A 3BB7A 3BPMA 2JQGR 2ARYA 1A6RA 5K16A 3OF9A 2FTDA 3RNVA 1PPDA 3USVA 6PADA 1CS8A 4K7CA 5CHTA 5JH3A 4M0WA 3ZUAA 4QBBA 4ZUXU 3BOWA 2XU5A 4RNAA 4BOPA 1PPNA 1PPPA 4YYUA 4I04A 3W30A 1Y4HA 3PRMA 1GLOA 3BWKA 5CHVA 3OISA 1AECA 1PBHA 2HXZA 2AS8A 1PADA 2DZZA 1GCBA 2NQDB 2B1NA 2IBIA 3IHPA 1EWMA 3E9SA 4QRVA 2BDZA 3MORA 3PHUA 5CVMA 4OELA 4ZTBA 1Y08A 4A5UA 1YALA 4YYVA 4I05A 3I3TA 1F2AA 2AGAA 2AIMA 4Q8HA 2G8EA 3O65A 3P5UA 1F2BA 1S4VA 2DC8A 2O6XA 4QH6A 4BQVA 1CPJA 1YK8A 2XU1A 3LXSA 1CJLA 1NB3A 2BDLA 4BOZA 3V6EA 3IUTA 5E6JA 3RVVA 4MI7A 3OVZA 2ATOA 3KFQA 1PIPA 1NLJA 3ZNHA 3QT4A 4MM3B 2FE8A 3W31A 1ATKA 4YYSA 3WXFA 3OVXA 1EWPA 4QRGA 1CB5A 4PP2E 3N3KA 1CSBB 4CDFB 2R9OA 7PCKA 3HHAA 4XUIA 2FRAA 4YYQA 3H8CA 4RF1A 4FJCA 3QSDA 4G54A 4R3DA 3QJ3A 4FIPA 3PW3A 3PBHA 1UKFA 2CIOA 5JZEA 3H8BA 2PNSA 2DC7A 1DF0A 3KX1A 4Q8GA 3RVWA 1CVZA 3NHEA 1XKGA 4OVZA 2FT2A 4KLBA 4RKXA 4MSXA 2J7QC 4DMXA 4W4UA 3CBKA 2R9NA 4OW0A 1NQCA 4BSQA 3OQCA 2F1GA 4W5CA 1YVBA 2AU1A 1PXVA 2NQAA 1U9VA 5A24A 1ZCMA 1KFXL 1BP4A 1QMYA 1DEUA 4GUAA 3PSEA 2AVWA 2UZJA 3LFYA 2OZ2A 2Y5BA 2HWKA 3CBJA 4YV8A 1DKIA 2DC9A 5CVNB 2Z84A 1TL9A 4AXMA 4RY2A 1THEA 3M99A 1FH0A 4IP3A 2PADA 3N3GA 2R6NA 3MHSA 2G8JA 4BOSA 3K24A 2CB5A 2G6DA 4I07A 1YZBA 5EF4A 1EWOA 3ERVA 4HWYA 4CDDB 3P5WA 2DJFB 2AYOA 2E00A 3PRPA 3O0UA 3S3RA 5J94A 1KFUL 3U8EA 5PADA 2FO5A
chains in the Genus database with same CATH topology
3C0RA 3IFUA 4D8IA 4BOQA 3BBAA 3BY4A 4REZA 3BB7A 4RF1A 4R3DA 4HXDB 5EZSA 3PT2A 3TRKA 3MTVA 3RNVA 1UKFA 5JZEA 3TMPA 4OVZB 4OVZA 4IUMA 4M0WA 3PHXA 4RKXA 2J7QC 4RNAA 4BOPA 5KO3A 3PHWA 4OW0A 3OQCA 5EZQA 3W30A 4D8EA 3PRMA 1PVJA 2BTWB 2BU3A 4GUAA 3PSEA 2UZJA 3E9SA 2HWKA 3PHUA 1DKIA 4ZTBA 2J7QA 4P16A 4A5UA 2Z84A 4BOUA 3MP2A 2JTCA 2AGAA 4IP3A 2JRIA 3O65A 2BTWA 4BOSA 3MJ5A 4BOZA 1YZBA 4D8BA 2DOSA 5E6JA 4PT5A 4WURA 4MI7A 4RF0A 3PRPA 3ZNHA 3B21A 4XZXA 4MM3B 2FE8A 3W31A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PT2 A;  3C0R A;  3PRM A;  3PRP A;  3TMP A;  4BOS A;  4BOP A;  3ZNH A;  3PHU A;  4BOU A;  3PHW A;  3PHX A;  3BY4 A;  3PSE A;  4BOZ A;  4BOQ A;  5JZE A;  4HXD B; 
#chains in the Genus database with same CATH topology
 4P6G A;  3WXG A;  3O1G A;  1AU4 A;  1O0E A;  3HD3 A;  1AU0 A;  2F7D A;  4BOQ A;  4W5B A;  3OF8 A;  2E02 A;  3S3Q A;  1CTE A;  2OUL A;  1YK7 A;  4REZ A;  4CDC B;  1TLO A;  1YT7 A;  3K9M A;  1CQD A;  5EZS A;  2R9M A;  3TRK A;  1VJV A;  1QDQ A;  2C0Y A;  2XU3 A;  2P86 A;  1VSN A;  3B79 A;  3BCN A;  1MEM A;  2GFO A;  3C9E A;  4OVZ B;  2VHS A;  2FYE A;  2HH5 A;  2JQF R;  1QXP A;  1AU2 A;  4MZS A;  5EGW A;  4OEM A;  1NL6 A;  1U9Q X;  3BPF A;  1PE6 A;  5KO3 A;  5CVO B;  3H6S A;  1GMY A;  1POP A;  4N79 A;  1MHW A;  2BTW B;  1ME3 A;  1AIM A;  4N8W A;  2E03 A;  1F29 A;  2OP3 A;  1X9Y A;  1JQP A;  1U9W A;  2H7J A;  4P16 A;  1MDW A;  4QRX A;  3MP2 A;  3HHI A;  1NPZ A;  3KW9 A;  2R9C A;  4PAD A;  1BQI A;  1BGO A;  2AUZ A;  1AYW A;  2JRI A;  3D6S A;  2HHN A;  5FPW A;  2YJB A;  1STF E;  2BTW A;  1AYV A;  1ICF A;  3KWZ A;  1KHP A;  1ME4 A;  1MEG A;  1ITO A;  2G7Y A;  4P6E A;  1KHQ A;  1TU6 A;  3E1Z B;  5JA7 A;  3MJ5 A;  1ZIV A;  2DZY A;  1F2C A;  1BY8 A;  1M6D A;  2DOS A;  2DCD A;  2YJ9 A;  4WUR A;  3DF0 A;  2DJG B;  3B21 A;  4XZX A;  2ACT A;  2E01 A;  3KSE A;  2AUX A;  1MS6 A;  2YJ2 A;  4YYR A;  2HD5 A;  3H7D A;  4D8I A;  3WXE A;  3H89 A;  3P5V A;  3BC3 A;  3KWB X;  4N4Z A;  4YVA A;  4X6J A;  2P0R A;  1U5I A;  1KXR A;  2NQI A;  2DCB A;  4PI3 A;  3HWN A;  1MIR A;  4HXD B;  2DCA A;  2DCC A;  3PT2 A;  3TNX A;  5F02 A;  3N4C A;  1HUC B;  3MTV A;  4PP1 A;  4XR7 A;  1SNK A;  3TMP A;  3MTN A;  2B1M A;  4BS6 A;  4FK5 A;  3AI8 A;  2Y6E A;  2FUD A;  4IUM A;  3IOQ A;  4CDE B;  3PDF A;  3PHX A;  4MZO A;  3CH3 X;  4WA6 A;  2PRE A;  1K3B B;  4CZW A;  1SP4 B;  3V6C A;  3PHW A;  5EZQ A;  4D8E A;  1PPO A;  1PVJ A;  2DC6 A;  2WBF X;  3F75 A;  8PCH A;  3K8U A;  3P5X A;  2XU4 A;  2BU3 A;  3CH2 X;  1EF7 A;  1U9X A;  2YJC A;  4BS5 A;  3KKU A;  2J7Q A;  1NB5 A;  4BOU A;  1CV8 A;  2JTC A;  4X6H A;  1QOL A;  2VHF A;  2AYN A;  3PNR A;  3IMA A;  2R9F A;  3F5V A;  1GEC E;  3GCB A;  4DMY A;  1IWD A;  2IPP B;  4BPV A;  2PBH A;  3MHH A;  1PCI A;  4D8B A;  2FRQ A;  4PT5 A;  4RF0 A;  1EWL A;  4YYW A;  4AXL A;  3IEJ A;  1Q6K A;  2FQ9 A;  1AU3 A;  2GHU A;  3C0R A;  3IFU A;  3RVX A;  4X6I A;  2P7U A;  3IV2 A;  9PAP A;  2YJ8 A;  3BBA A;  1AYU A;  2NQG A;  3BY4 A;  3I06 A;  3BB7 A;  3BPM A;  2JQG R;  2ARY A;  1A6R A;  5K16 A;  3OF9 A;  2FTD A;  3RNV A;  1PPD A;  3USV A;  6PAD A;  1CS8 A;  4K7C A;  5CHT A;  5JH3 A;  4M0W A;  3ZUA A;  4QBB A;  4ZUX U;  3BOW A;  2XU5 A;  4RNA A;  4BOP A;  1PPN A;  1PPP A;  4YYU A;  4I04 A;  3W30 A;  1Y4H A;  3PRM A;  1GLO A;  3BWK A;  5CHV A;  3OIS A;  1AEC A;  1PBH A;  2HXZ A;  2AS8 A;  1PAD A;  2DZZ A;  1GCB A;  2NQD B;  2B1N A;  2IBI A;  3IHP A;  1EWM A;  3E9S A;  4QRV A;  2BDZ A;  3MOR A;  3PHU A;  5CVM A;  4OEL A;  4ZTB A;  1Y08 A;  4A5U A;  1YAL A;  4YYV A;  4I05 A;  3I3T A;  1F2A A;  2AGA A;  2AIM A;  4Q8H A;  2G8E A;  3O65 A;  3P5U A;  1F2B A;  1S4V A;  2DC8 A;  2O6X A;  4QH6 A;  4BQV A;  1CPJ A;  1YK8 A;  2XU1 A;  3LXS A;  1CJL A;  1NB3 A;  2BDL A;  4BOZ A;  3V6E A;  3IUT A;  5E6J A;  3RVV A;  4MI7 A;  3OVZ A;  2ATO A;  3KFQ A;  1PIP A;  1NLJ A;  3ZNH A;  3QT4 A;  4MM3 B;  2FE8 A;  3W31 A;  1ATK A;  4YYS A;  3WXF A;  3OVX A;  1EWP A;  4QRG A;  1CB5 A;  4PP2 E;  3N3K A;  1CSB B;  4CDF B;  2R9O A;  7PCK A;  3HHA A;  4XUI A;  2FRA A;  4YYQ A;  3H8C A;  4RF1 A;  4FJC A;  3QSD A;  4G54 A;  4R3D A;  3QJ3 A;  4FIP A;  3PW3 A;  3PBH A;  1UKF A;  2CIO A;  5JZE A;  3H8B A;  2PNS A;  2DC7 A;  1DF0 A;  3KX1 A;  4Q8G A;  3RVW A;  1CVZ A;  3NHE A;  1XKG A;  4OVZ A;  2FT2 A;  4KLB A;  4RKX A;  4MSX A;  2J7Q C;  4DMX A;  4W4U A;  3CBK A;  2R9N A;  4OW0 A;  1NQC A;  4BSQ A;  3OQC A;  2F1G A;  4W5C A;  1YVB A;  2AU1 A;  1PXV A;  2NQA A;  1U9V A;  5A24 A;  1ZCM A;  1KFX L;  1BP4 A;  1QMY A;  1DEU A;  4GUA A;  3PSE A;  2AVW A;  2UZJ A;  3LFY A;  2OZ2 A;  2Y5B A;  2HWK A;  3CBJ A;  4YV8 A;  1DKI A;  2DC9 A;  5CVN B;  2Z84 A;  1TL9 A;  4AXM A;  4RY2 A;  1THE A;  3M99 A;  1FH0 A;  4IP3 A;  2PAD A;  3N3G A;  2R6N A;  3MHS A;  2G8J A;  4BOS A;  3K24 A;  2CB5 A;  2G6D A;  4I07 A;  1YZB A;  5EF4 A;  1EWO A;  3ERV A;  4HWY A;  4CDD B;  3P5W A;  2DJF B;  2AYO A;  2E00 A;  3PRP A;  3O0U A;  3S3R A;  5J94 A;  1KFU L;  3U8E A;  5PAD A;  2FO5 A; 
#chains in the Genus database with same CATH homology
 3C0R A;  3IFU A;  4D8I A;  4BOQ A;  3BBA A;  3BY4 A;  4REZ A;  3BB7 A;  4RF1 A;  4R3D A;  4HXD B;  5EZS A;  3PT2 A;  3TRK A;  3MTV A;  3RNV A;  1UKF A;  5JZE A;  3TMP A;  4OVZ B;  4OVZ A;  4IUM A;  4M0W A;  3PHX A;  4RKX A;  2J7Q C;  4RNA A;  4BOP A;  5KO3 A;  3PHW A;  4OW0 A;  3OQC A;  5EZQ A;  3W30 A;  4D8E A;  3PRM A;  1PVJ A;  2BTW B;  2BU3 A;  4GUA A;  3PSE A;  2UZJ A;  3E9S A;  2HWK A;  3PHU A;  1DKI A;  4ZTB A;  2J7Q A;  4P16 A;  4A5U A;  2Z84 A;  4BOU A;  3MP2 A;  2JTC A;  2AGA A;  4IP3 A;  2JRI A;  3O65 A;  2BTW A;  4BOS A;  3MJ5 A;  4BOZ A;  1YZB A;  4D8B A;  2DOS A;  5E6J A;  4PT5 A;  4WUR A;  4MI7 A;  4RF0 A;  3PRP A;  3ZNH A;  3B21 A;  4XZX A;  4MM3 B;  2FE8 A;  3W31 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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