4IUMA

Equine arteritis virus papain-like protease 2 (plp2) covalently bound to ubiquitin
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
127
structure length
127
Chain Sequence
GYNPPGDGACGYRCLAFMNGATVVSAGCSSDLWCDDELAYRVFQLSPTFTVTIPGGRVCPNAKYAMICDKQHWRVKRAKGVGLCLDESCFRGICNCQRMSGPPPAPVSAAVLDHILEAATFGNVRVV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Deubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cells.
pubmed doi rcsb
molecule tags Hydrolase/protein binding
source organism Equine arteritis virus
molecule keywords papain-like protease 2
total genus 36
structure length 127
sequence length 127
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 2013-01-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF05412 Peptidase_C33 Equine arterivirus Nsp2-type cysteine proteinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.160 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cathepsin B; Chain A 4iumA00
4IUMA
chains in the Genus database with same CATH superfamily
2Y5BA 5J94A 3P5WA 1AIMA 4CZWA 3BBAA 2BTWB 1KFUL 3BY4A 3BB7A 3DF0A 1NPZA 4FIPA 3PSEA 1Y08A 3MJ5A 2DCAA 1EWPA 4ZUXU 3IMAA 3P5UA 1M6DA 2R9OA 2AS8A 4I04A 2P7UA 1XKGA 1MEMA 4QBBA 4D8EA 3BWKA 1AU3A 3BC3A 1ITOA 1MIRA 1AYUA 2VHFA 4PP2E 4IUMA 4MZOA 1K3BB 1MS6A 1HUCB 1TLOA 4I05A 1O0EA 8PCHA 2FT2A 3K9MA 2F1GA 1MEGA 3MTVA 1PADA 3RVVA 1ZCMA 4OVZB 2BTWA 1EWOA 2FYEA 2NQIA 1GLOA 3O1GA 2PBHA 3NHEA 3PW3A 2GHUA 3QT4A 2HHNA 1ME4A 3O65A 1NL6A 2O6XA 2HXZA 1U9XA 3KSEA 2FRQA 4A5UA 4AXMA 2ACTA 4W5BA 3P5XA 4BPVA 1QOLA 2DZZA 1JQPA 1CVZA 2F7DA 2BDLA 1Y4HA 3LXSA 4YYWA 2H7JA 4M0WA 1U5IA 2JQGR 2JRIA 3PBHA 1BY8A 2E00A 3H7DA 1CPJA 2C0YA 1PPNA 1YK7A 1KHPA 2AVWA 2FQ9A 4R3DA 4BOUA 1A6RA 2PADA 2Z84A 2J7QA 3USVA 2NQAA 4YYUA 1FH0A 4P16A 1PXVA 3CH3X 4BQVA 4YYRA 2YJ8A 1YT7A 9PAPA 2DZYA 1DF0A 4CDFB 1AYWA 4OVZA 4HWYA 1GCBA 2P0RA 3E1ZB 3MHSA 4PI3A 4RF1A 1F29A 1UKFA 1YALA 1PPOA 3IFUA 1AYVA 3AI8A 3QJ3A 2DC7A 1SNKA 4BOZA 1AU0A 3LFYA 2PREA 1DKIA 2DOSA 5JH3A 1PE6A 2OULA 3S3RA 7PCKA 1CSBB 1KXRA 1IWDA 4PT5A 3MHHA 1GMYA 1PIPA 2JTCA 3D6SA 1CB5A 4D8BA 3TMPA 2E01A 2Y6EA 3O0UA 1PPPA 1F2AA 2GFOA 4FJCA 3I3TA 1BQIA 2P86A 2AGAA 4XUIA 3ZNHA 2AYNA 2J7QC 4QRVA 4KLBA 1POPA 3IV2A 2CB5A 1ICFA 2R9MA 2IBIA 3HD3A 1BP4A 2YJBA 2XU1A 5CVOB 1F2BA 3CBJA 1YZBA 2FUDA 3MORA 4P6GA 1F2CA 5CHTA 3PDFA 1BGOA 4D8IA 3WXEA 1VJVA 1PCIA 2HH5A 1PVJA 4HXDB 4CDEB 3K8UA 4X6HA 3RVWA 3HHAA 4DMXA 3BCNA 2JQFR 2B1MA 5KO3A 4XR7A 4OEMA 3PHXA 3S3QA 3KX1A 5EZSA 1STFE 5F02A 5E6JA 4W4UA 2R9CA 1KHQA 3ZUAA 2OP3A 4IP3A 1NQCA 3N3GA 3PHWA 2AUZA 3C0RA 2R6NA 2DCDA 4X6JA 1QMYA 2G8EA 3GCBA 1EWMA 3H8CA 2B1NA 2VHSA 5EGWA 3IOQA 4X6IA 3C9EA 4I07A 2BDZA 1S4VA 4MI7A 1EF7A 2IPPB 4CDCB 1TL9A 1CS8A 2FTDA 2NQDB 4BOSA 3K24A 3TNXA 4QRGA 1VSNA 2G8JA 4OW0A 3BOWA 4YV8A 2YJCA 3KFQA 4Q8GA 1THEA 3KWZA 2XU4A 1KFXL 3IHPA 1TU6A 5FPWA 3IUTA 2FE8A 2PNSA 1QXPA 3F5VA 2R9NA 1AU4A 2YJ2A 1NB3A 3CBKA 5CVNB 1GECE 5PADA 4YVAA 4YYQA 3P5VA 4RF0A 3OF9A 4BOQA 3F75A 3ERVA 3I06A 4BOPA 2DC9A 2ATOA 2HWKA 3WXGA 1YVBA 5K16A 6PADA 4N8WA 3QSDA 4N79A 2AYOA 3N4CA 1MHWA 4RNAA 1CV8A 4N4ZA 3TRKA 4YYSA 2UZJA 2DCBA 4RY2A 1ATKA 3BPMA 1AU2A 3PT2A 2G6DA 1U9VA 5EF4A 1ME3A 2AIMA 2HD5A 2DJFB 4XZXA 2WBFX 4RKXA 3E9SA 3V6CA 4ZTBA 4MM3B 3PNRA 4CDDB 5CHVA 1SP4B 2YJ9A 2R9FA 2XU3A 1ZIVA 3W31A 1PPDA 5A24A 4PADA 4QH6A 4K7CA 4P6EA 4REZA 3B21A 3U8EA 3H8BA 3OVXA 2FRAA 4BS5A 4MSXA 2NQGA 1U9QX 3OVZA 2AU1A 5CVMA 4WURA 4FK5A 4BSQA 2DC6A 4MZSA 3MTNA 5JZEA 3RVXA 3H89A 1QDQA 4G54A 2BU3A 4GUAA 4DMYA 4QRXA 4YYVA 2E03A 2G7YA 2XU5A 4PP1A 4OELA 3CH2X 3OF8A 1CJLA 3OQCA 1X9YA 2FO5A 1PBHA 3OISA 1NLJA 3PRPA 2ARYA 1MDWA 3IEJA 5JA7A 1NB5A 2DC8A 1AECA 2AUXA 3PHUA 3B79A 1YK8A 1DEUA 3M99A 4WA6A 2E02A 4BS6A 4AXLA 1EWLA 3KWBX 1CQDA 2DCCA 2OZ2A 4W5CA 1U9WA 1Q6KA 3V6EA 3W30A 1CTEA 2DJGB 3KW9A 3N3KA 3RNVA 3BPFA 5EZQA 3WXFA 3H6SA 3HHIA 3MP2A 3HWNA 2CIOA 4Q8HA 3PRMA 3KKUA
chains in the Genus database with same CATH topology
3PHXA 4BOUA 5EZSA 2Z84A 4XZXA 2J7QA 3BBAA 5E6JA 4RKXA 2BTWB 3E9SA 3BY4A 4IP3A 4ZTBA 3BB7A 4MM3B 4P16A 3PHWA 3PSEA 3C0RA 3MJ5A 3W31A 4OVZA 4REZA 3B21A 4MI7A 4RF1A 4BOSA 1UKFA 3IFUA 4D8EA 4OW0A 4BOZA 4WURA 1DKIA 4IUMA 2DOSA 5JZEA 4PT5A 2FE8A 2BU3A 4GUAA 2JTCA 3MTVA 4D8BA 3TMPA 3OQCA 4RF0A 4OVZB 2BTWA 4BOQA 3PRPA 2AGAA 4BOPA 2HWKA 3O65A 3ZNHA 2J7QC 3PHUA 4A5UA 4RNAA 3TRKA 2UZJA 1YZBA 3W30A 3PT2A 4M0WA 2JRIA 4D8IA 3RNVA 5EZQA 1PVJA 4HXDB 3MP2A 5KO3A 3PRMA 4R3DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IUM A; 
#chains in the Genus database with same CATH topology
 2Y5B A;  5J94 A;  3P5W A;  1AIM A;  4CZW A;  3BBA A;  2BTW B;  1KFU L;  3BY4 A;  3BB7 A;  3DF0 A;  1NPZ A;  4FIP A;  3PSE A;  1Y08 A;  3MJ5 A;  2DCA A;  1EWP A;  4ZUX U;  3IMA A;  3P5U A;  1M6D A;  2R9O A;  2AS8 A;  4I04 A;  2P7U A;  1XKG A;  1MEM A;  4QBB A;  4D8E A;  3BWK A;  1AU3 A;  3BC3 A;  1ITO A;  1MIR A;  1AYU A;  2VHF A;  4PP2 E;  4IUM A;  4MZO A;  1K3B B;  1MS6 A;  1HUC B;  1TLO A;  4I05 A;  1O0E A;  8PCH A;  2FT2 A;  3K9M A;  2F1G A;  1MEG A;  3MTV A;  1PAD A;  3RVV A;  1ZCM A;  4OVZ B;  2BTW A;  1EWO A;  2FYE A;  2NQI A;  1GLO A;  3O1G A;  2PBH A;  3NHE A;  3PW3 A;  2GHU A;  3QT4 A;  2HHN A;  1ME4 A;  3O65 A;  1NL6 A;  2O6X A;  2HXZ A;  1U9X A;  3KSE A;  2FRQ A;  4A5U A;  4AXM A;  2ACT A;  4W5B A;  3P5X A;  4BPV A;  1QOL A;  2DZZ A;  1JQP A;  1CVZ A;  2F7D A;  2BDL A;  1Y4H A;  3LXS A;  4YYW A;  2H7J A;  4M0W A;  1U5I A;  2JQG R;  2JRI A;  3PBH A;  1BY8 A;  2E00 A;  3H7D A;  1CPJ A;  2C0Y A;  1PPN A;  1YK7 A;  1KHP A;  2AVW A;  2FQ9 A;  4R3D A;  4BOU A;  1A6R A;  2PAD A;  2Z84 A;  2J7Q A;  3USV A;  2NQA A;  4YYU A;  1FH0 A;  4P16 A;  1PXV A;  3CH3 X;  4BQV A;  4YYR A;  2YJ8 A;  1YT7 A;  9PAP A;  2DZY A;  1DF0 A;  4CDF B;  1AYW A;  4OVZ A;  4HWY A;  1GCB A;  2P0R A;  3E1Z B;  3MHS A;  4PI3 A;  4RF1 A;  1F29 A;  1UKF A;  1YAL A;  1PPO A;  3IFU A;  1AYV A;  3AI8 A;  3QJ3 A;  2DC7 A;  1SNK A;  4BOZ A;  1AU0 A;  3LFY A;  2PRE A;  1DKI A;  2DOS A;  5JH3 A;  1PE6 A;  2OUL A;  3S3R A;  7PCK A;  1CSB B;  1KXR A;  1IWD A;  4PT5 A;  3MHH A;  1GMY A;  1PIP A;  2JTC A;  3D6S A;  1CB5 A;  4D8B A;  3TMP A;  2E01 A;  2Y6E A;  3O0U A;  1PPP A;  1F2A A;  2GFO A;  4FJC A;  3I3T A;  1BQI A;  2P86 A;  2AGA A;  4XUI A;  3ZNH A;  2AYN A;  2J7Q C;  4QRV A;  4KLB A;  1POP A;  3IV2 A;  2CB5 A;  1ICF A;  2R9M A;  2IBI A;  3HD3 A;  1BP4 A;  2YJB A;  2XU1 A;  5CVO B;  1F2B A;  3CBJ A;  1YZB A;  2FUD A;  3MOR A;  4P6G A;  1F2C A;  5CHT A;  3PDF A;  1BGO A;  4D8I A;  3WXE A;  1VJV A;  1PCI A;  2HH5 A;  1PVJ A;  4HXD B;  4CDE B;  3K8U A;  4X6H A;  3RVW A;  3HHA A;  4DMX A;  3BCN A;  2JQF R;  2B1M A;  5KO3 A;  4XR7 A;  4OEM A;  3PHX A;  3S3Q A;  3KX1 A;  5EZS A;  1STF E;  5F02 A;  5E6J A;  4W4U A;  2R9C A;  1KHQ A;  3ZUA A;  2OP3 A;  4IP3 A;  1NQC A;  3N3G A;  3PHW A;  2AUZ A;  3C0R A;  2R6N A;  2DCD A;  4X6J A;  1QMY A;  2G8E A;  3GCB A;  1EWM A;  3H8C A;  2B1N A;  2VHS A;  5EGW A;  3IOQ A;  4X6I A;  3C9E A;  4I07 A;  2BDZ A;  1S4V A;  4MI7 A;  1EF7 A;  2IPP B;  4CDC B;  1TL9 A;  1CS8 A;  2FTD A;  2NQD B;  4BOS A;  3K24 A;  3TNX A;  4QRG A;  1VSN A;  2G8J A;  4OW0 A;  3BOW A;  4YV8 A;  2YJC A;  3KFQ A;  4Q8G A;  1THE A;  3KWZ A;  2XU4 A;  1KFX L;  3IHP A;  1TU6 A;  5FPW A;  3IUT A;  2FE8 A;  2PNS A;  1QXP A;  3F5V A;  2R9N A;  1AU4 A;  2YJ2 A;  1NB3 A;  3CBK A;  5CVN B;  1GEC E;  5PAD A;  4YVA A;  4YYQ A;  3P5V A;  4RF0 A;  3OF9 A;  4BOQ A;  3F75 A;  3ERV A;  3I06 A;  4BOP A;  2DC9 A;  2ATO A;  2HWK A;  3WXG A;  1YVB A;  5K16 A;  6PAD A;  4N8W A;  3QSD A;  4N79 A;  2AYO A;  3N4C A;  1MHW A;  4RNA A;  1CV8 A;  4N4Z A;  3TRK A;  4YYS A;  2UZJ A;  2DCB A;  4RY2 A;  1ATK A;  3BPM A;  1AU2 A;  3PT2 A;  2G6D A;  1U9V A;  5EF4 A;  1ME3 A;  2AIM A;  2HD5 A;  2DJF B;  4XZX A;  2WBF X;  4RKX A;  3E9S A;  3V6C A;  4ZTB A;  4MM3 B;  3PNR A;  4CDD B;  5CHV A;  1SP4 B;  2YJ9 A;  2R9F A;  2XU3 A;  1ZIV A;  3W31 A;  1PPD A;  5A24 A;  4PAD A;  4QH6 A;  4K7C A;  4P6E A;  4REZ A;  3B21 A;  3U8E A;  3H8B A;  3OVX A;  2FRA A;  4BS5 A;  4MSX A;  2NQG A;  1U9Q X;  3OVZ A;  2AU1 A;  5CVM A;  4WUR A;  4FK5 A;  4BSQ A;  2DC6 A;  4MZS A;  3MTN A;  5JZE A;  3RVX A;  3H89 A;  1QDQ A;  4G54 A;  2BU3 A;  4GUA A;  4DMY A;  4QRX A;  4YYV A;  2E03 A;  2G7Y A;  2XU5 A;  4PP1 A;  4OEL A;  3CH2 X;  3OF8 A;  1CJL A;  3OQC A;  1X9Y A;  2FO5 A;  1PBH A;  3OIS A;  1NLJ A;  3PRP A;  2ARY A;  1MDW A;  3IEJ A;  5JA7 A;  1NB5 A;  2DC8 A;  1AEC A;  2AUX A;  3PHU A;  3B79 A;  1YK8 A;  1DEU A;  3M99 A;  4WA6 A;  2E02 A;  4BS6 A;  4AXL A;  1EWL A;  3KWB X;  1CQD A;  2DCC A;  2OZ2 A;  4W5C A;  1U9W A;  1Q6K A;  3V6E A;  3W30 A;  1CTE A;  2DJG B;  3KW9 A;  3N3K A;  3RNV A;  3BPF A;  5EZQ A;  3WXF A;  3H6S A;  3HHI A;  3MP2 A;  3HWN A;  2CIO A;  4Q8H A;  3PRM A;  3KKU A; 
#chains in the Genus database with same CATH homology
 3PHX A;  4BOU A;  5EZS A;  2Z84 A;  4XZX A;  2J7Q A;  3BBA A;  5E6J A;  4RKX A;  2BTW B;  3E9S A;  3BY4 A;  4IP3 A;  4ZTB A;  3BB7 A;  4MM3 B;  4P16 A;  3PHW A;  3PSE A;  3C0R A;  3MJ5 A;  3W31 A;  4OVZ A;  4REZ A;  3B21 A;  4MI7 A;  4RF1 A;  4BOS A;  1UKF A;  3IFU A;  4D8E A;  4OW0 A;  4BOZ A;  4WUR A;  1DKI A;  4IUM A;  2DOS A;  5JZE A;  4PT5 A;  2FE8 A;  2BU3 A;  4GUA A;  2JTC A;  3MTV A;  4D8B A;  3TMP A;  3OQC A;  4RF0 A;  4OVZ B;  2BTW A;  4BOQ A;  3PRP A;  2AGA A;  4BOP A;  2HWK A;  3O65 A;  3ZNH A;  2J7Q C;  3PHU A;  4A5U A;  4RNA A;  3TRK A;  2UZJ A;  1YZB A;  3W30 A;  3PT2 A;  4M0W A;  2JRI A;  4D8I A;  3RNV A;  5EZQ A;  1PVJ A;  4HXD B;  3MP2 A;  5KO3 A;  3PRM A;  4R3D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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