4BOQA

Structure of otud2 otu domain
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
175
structure length
175
Chain Sequence
KRGASSYVRETLPVLTRTVVPADNSCLFTSVYYVVEGGVLNPACAPEMRRLIAQIVASDPDFYSEAILGKTNQEYCDWIKRDDTWGGAIEISILSKFYQCEICVVDTQTVRIDRFGEDAGYTKRVLLIYDGIHYDPLQRNFPDPDTPPLTIFSSNDDIVLVQALELADEARRRRQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords UBIQUITIN THIOESTERASE OTU1
total genus 55
structure length 175
sequence length 175
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 2013-05-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02338 OTU OTU-like cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.80 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cathepsin B; Chain A 4boqA00
4BOPA 3PRPA 4BOZA 4BOQA 3TMPA 4BOUA 4HXDB 3C0RA 3BY4A 5JZEA 3PRMA 3PT2A 4BOSA 3PSEA 3PHUA 3PHXA 3ZNHA 3PHWA
chains in the Genus database with same CATH superfamily
4XR7A 1PVJA 4YV8A 2CIOA 4XUIA 3F5VA 3N3KA 3WXFA 1NB3A 2E03A 3KWBX 1HUCB 1F2AA 3S3QA 1M6DA 4IUMA 4D8BA 3N4CA 1CV8A 2E02A 2Y5BA 4WA6A 4YYUA 2AYNA 4P6EA 4KLBA 3K9MA 2XU1A 2C0YA 1EWOA 2B1NA 2Z84A 3NHEA 1DEUA 4P6GA 1EWPA 2AYOA 4Q8HA 3TNXA 1KHQA 3IHPA 4D8IA 4BOUA 1AU4A 2IBIA 3MJ5A 3RVVA 1AU2A 2NQAA 1CS8A 3MORA 1Q6KA 2DC8A 3PW3A 4PP1A 2NQDB 1TU6A 4QBBA 1THEA 3PSEA 2DJGB 1NLJA 3LFYA 2JTCA 4X6IA 1ZCMA 1MS6A 3BOWA 4W5CA 2DJFB 2BDLA 1AIMA 4W4UA 3KX1A 1ME4A 8PCHA 4G54A 3E1ZB 1MDWA 1Y4HA 2YJ9A 2R9NA 3BPFA 4OVZB 3IOQA 3N3GA 2G8JA 1AYVA 4QRXA 2R9OA 1ICFA 3S3RA 3KW9A 1MEMA 2DOSA 4BS6A 4FJCA 5EF4A 3W31A 4IP3A 1O0EA 3H7DA 2E01A 4ZTBA 2B1MA 3I3TA 1GCBA 3CH2X 2FO5A 4AXMA 1PPPA 1X9YA 2DZZA 2E00A 1PADA 1U9XA 4BOSA 2XU4A 2DC7A 1U9VA 4A5UA 5JZEA 2DCBA 3M99A 4BOZA 3KWZA 3TMPA 3OF9A 3KFQA 3AI8A 5JH3A 3PDFA 4P16A 4K7CA 3MP2A 3OISA 1BY8A 1AECA 3CBJA 4ZUXU 5J94A 3RVXA 1CSBB 2YJ2A 2DZYA 4W5BA 2PNSA 3IFUA 1NB5A 2VHFA 4PI3A 1YK8A 2BTWB 3U8EA 4YYWA 4I04A 1JQPA 4PT5A 3C9EA 4RF1A 3BY4A 2JQGR 2CB5A 2R9CA 3LXSA 2HWKA 5EGWA 3OF8A 3H8BA 1MHWA 2DCDA 4BOPA 1YT7A 1CQDA 3BPMA 3H89A 6PADA 2NQIA 2VHSA 1ITOA 1PPNA 4DMYA 5PADA 2OULA 3V6CA 5K16A 4QRGA 3RNVA 4X6JA 4CDFB 1DKIA 3MHHA 1NQCA 3QJ3A 2H7JA 1PE6A 3O1GA 1VSNA 3F75A 2DC9A 3H8CA 1AYUA 2JQFR 3P5UA 1AYWA 1SNKA 1CJLA 2AS8A 3PT2A 1YK7A 4OEMA 1SP4B 3I06A 3MTNA 4WURA 4YYSA 2G8EA 3IUTA 1CB5A 1EWMA 2FRAA 1F2CA 5F02A 1EWLA 2BU3A 4R3DA 4M0WA 1CVZA 2FE8A 1GLOA 2AU1A 1NL6A 3P5XA 1BQIA 4BSQA 1YALA 2PREA 1MEGA 2J7QA 2HD5A 2UZJA 3P5VA 3PHXA 2O6XA 2F7DA 1EF7A 1ME3A 4BS5A 3CBKA 2GFOA 5FPWA 3HHAA 3RVWA 2J7QC 4OVZA 4QRVA 4DMXA 3BB7A 3ERVA 9PAPA 1ZIVA 4BPVA 1UKFA 4YYRA 4D8EA 1U9QX 3PHUA 3QSDA 2BDZA 1PCIA 3HHIA 3IV2A 2XU5A 1IWDA 1KHPA 1QDQA 2FRQA 2G6DA 4OELA 1PPDA 4XZXA 2HXZA 2IPPB 3MHSA 4YVAA 4MZOA 1AU3A 2HH5A 3OQCA 4QH6A 4MSXA 3H6SA 3K24A 3OVXA 1TL9A 4YYVA 3PRMA 3BWKA 2AVWA 4FIPA 4Q8GA 1KXRA 4N8WA 1GMYA 4X6HA 2ATOA 3KKUA 2JRIA 4RNAA 1XKGA 5JA7A 4RF0A 3E9SA 2ARYA 2FQ9A 1QMYA 3ZNHA 2FUDA 3GCBA 3PRPA 3PBHA 3B21A 3TRKA 1CPJA 3QT4A 3O65A 1QXPA 4REZA 2P7UA 4CDDB 2Y6EA 2BTWA 4N4ZA 2FYEA 3KSEA 5CVNB 1FH0A 3PHWA 1AU0A 3CH3X 2YJCA 3P5WA 2DCAA 2AIMA 1MIRA 5KO3A 1BGOA 1PIPA 4CDCB 3BBAA 4YYQA 1YVBA 2PBHA 1PPOA 2DCCA 1PXVA 1U9WA 1K3BB 2F1GA 7PCKA 3BC3A 2OZ2A 3HD3A 4OW0A 4PP2E 5EZQA 1STFE 4MZSA 5E6JA 1F29A 2DC6A 1ATKA 5EZSA 4BOQA 2AUZA 2PADA 1GECE 2FT2A 1VJVA 5CHVA 4CDEB 4RY2A 2R6NA 2AUXA 4I05A 1A6RA 2FTDA 4HXDB 1S4VA 3BCNA 2GHUA 1F2BA 3V6EA 3ZUAA 4BQVA 3O0UA 2OP3A 3C0RA 1POPA 2AGAA 3MTVA 1DF0A 4RKXA 4CZWA 4HWYA 4MI7A 5CVMA 3W30A 5CHTA 4FK5A 1TLOA 2YJBA 3IEJA 3OVZA 1QOLA 2WBFX 3WXEA 3D6SA 4GUAA 2R9MA 3PNRA 1YZBA 2NQGA 3B79A 4N79A 1Y08A 3USVA 2P0RA 1BP4A 2HHNA 5CVOB 2YJ8A 2R9FA 2ACTA 3K8UA 3HWNA 3DF0A 1CTEA 1U5IA 1KFUL 4MM3B 1NPZA 4PADA 2P86A 5A24A 3IMAA 2XU3A 3WXGA 1KFXL 2G7YA 4AXLA 4I07A 1PBHA
chains in the Genus database with same CATH topology
1PVJA 4REZA 3PT2A 4BOSA 4A5UA 2BTWA 5JZEA 4BOZA 4IUMA 3PHWA 4WURA 4D8BA 3TMPA 5KO3A 2BU3A 4P16A 3BBAA 4R3DA 4M0WA 2Z84A 2FE8A 3MP2A 4OW0A 5EZQA 4D8IA 4BOUA 2J7QA 3MJ5A 2UZJA 3IFUA 3PHXA 5E6JA 5EZSA 4BOQA 2BTWB 4PT5A 2J7QC 4OVZA 4RF1A 3BY4A 3BB7A 4HXDB 3PSEA 1UKFA 4D8EA 3C0RA 3PHUA 2AGAA 3MTVA 4RKXA 2JTCA 4MI7A 2HWKA 3W30A 4BOPA 4XZXA 3OQCA 4GUAA 1YZBA 4OVZB 3PRMA 3RNVA 1DKIA 2DOSA 2JRIA 4RNAA 4RF0A 3W31A 3E9SA 4IP3A 4MM3B 3ZNHA 3PRPA 3B21A 4ZTBA 3TRKA 3O65A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BOP A;  3PRP A;  4BOZ A;  4BOQ A;  3TMP A;  4BOU A;  4HXD B;  3C0R A;  3BY4 A;  5JZE A;  3PRM A;  3PT2 A;  4BOS A;  3PSE A;  3PHU A;  3PHX A;  3ZNH A;  3PHW A; 
#chains in the Genus database with same CATH topology
 4XR7 A;  1PVJ A;  4YV8 A;  2CIO A;  4XUI A;  3F5V A;  3N3K A;  3WXF A;  1NB3 A;  2E03 A;  3KWB X;  1HUC B;  1F2A A;  3S3Q A;  1M6D A;  4IUM A;  4D8B A;  3N4C A;  1CV8 A;  2E02 A;  2Y5B A;  4WA6 A;  4YYU A;  2AYN A;  4P6E A;  4KLB A;  3K9M A;  2XU1 A;  2C0Y A;  1EWO A;  2B1N A;  2Z84 A;  3NHE A;  1DEU A;  4P6G A;  1EWP A;  2AYO A;  4Q8H A;  3TNX A;  1KHQ A;  3IHP A;  4D8I A;  4BOU A;  1AU4 A;  2IBI A;  3MJ5 A;  3RVV A;  1AU2 A;  2NQA A;  1CS8 A;  3MOR A;  1Q6K A;  2DC8 A;  3PW3 A;  4PP1 A;  2NQD B;  1TU6 A;  4QBB A;  1THE A;  3PSE A;  2DJG B;  1NLJ A;  3LFY A;  2JTC A;  4X6I A;  1ZCM A;  1MS6 A;  3BOW A;  4W5C A;  2DJF B;  2BDL A;  1AIM A;  4W4U A;  3KX1 A;  1ME4 A;  8PCH A;  4G54 A;  3E1Z B;  1MDW A;  1Y4H A;  2YJ9 A;  2R9N A;  3BPF A;  4OVZ B;  3IOQ A;  3N3G A;  2G8J A;  1AYV A;  4QRX A;  2R9O A;  1ICF A;  3S3R A;  3KW9 A;  1MEM A;  2DOS A;  4BS6 A;  4FJC A;  5EF4 A;  3W31 A;  4IP3 A;  1O0E A;  3H7D A;  2E01 A;  4ZTB A;  2B1M A;  3I3T A;  1GCB A;  3CH2 X;  2FO5 A;  4AXM A;  1PPP A;  1X9Y A;  2DZZ A;  2E00 A;  1PAD A;  1U9X A;  4BOS A;  2XU4 A;  2DC7 A;  1U9V A;  4A5U A;  5JZE A;  2DCB A;  3M99 A;  4BOZ A;  3KWZ A;  3TMP A;  3OF9 A;  3KFQ A;  3AI8 A;  5JH3 A;  3PDF A;  4P16 A;  4K7C A;  3MP2 A;  3OIS A;  1BY8 A;  1AEC A;  3CBJ A;  4ZUX U;  5J94 A;  3RVX A;  1CSB B;  2YJ2 A;  2DZY A;  4W5B A;  2PNS A;  3IFU A;  1NB5 A;  2VHF A;  4PI3 A;  1YK8 A;  2BTW B;  3U8E A;  4YYW A;  4I04 A;  1JQP A;  4PT5 A;  3C9E A;  4RF1 A;  3BY4 A;  2JQG R;  2CB5 A;  2R9C A;  3LXS A;  2HWK A;  5EGW A;  3OF8 A;  3H8B A;  1MHW A;  2DCD A;  4BOP A;  1YT7 A;  1CQD A;  3BPM A;  3H89 A;  6PAD A;  2NQI A;  2VHS A;  1ITO A;  1PPN A;  4DMY A;  5PAD A;  2OUL A;  3V6C A;  5K16 A;  4QRG A;  3RNV A;  4X6J A;  4CDF B;  1DKI A;  3MHH A;  1NQC A;  3QJ3 A;  2H7J A;  1PE6 A;  3O1G A;  1VSN A;  3F75 A;  2DC9 A;  3H8C A;  1AYU A;  2JQF R;  3P5U A;  1AYW A;  1SNK A;  1CJL A;  2AS8 A;  3PT2 A;  1YK7 A;  4OEM A;  1SP4 B;  3I06 A;  3MTN A;  4WUR A;  4YYS A;  2G8E A;  3IUT A;  1CB5 A;  1EWM A;  2FRA A;  1F2C A;  5F02 A;  1EWL A;  2BU3 A;  4R3D A;  4M0W A;  1CVZ A;  2FE8 A;  1GLO A;  2AU1 A;  1NL6 A;  3P5X A;  1BQI A;  4BSQ A;  1YAL A;  2PRE A;  1MEG A;  2J7Q A;  2HD5 A;  2UZJ A;  3P5V A;  3PHX A;  2O6X A;  2F7D A;  1EF7 A;  1ME3 A;  4BS5 A;  3CBK A;  2GFO A;  5FPW A;  3HHA A;  3RVW A;  2J7Q C;  4OVZ A;  4QRV A;  4DMX A;  3BB7 A;  3ERV A;  9PAP A;  1ZIV A;  4BPV A;  1UKF A;  4YYR A;  4D8E A;  1U9Q X;  3PHU A;  3QSD A;  2BDZ A;  1PCI A;  3HHI A;  3IV2 A;  2XU5 A;  1IWD A;  1KHP A;  1QDQ A;  2FRQ A;  2G6D A;  4OEL A;  1PPD A;  4XZX A;  2HXZ A;  2IPP B;  3MHS A;  4YVA A;  4MZO A;  1AU3 A;  2HH5 A;  3OQC A;  4QH6 A;  4MSX A;  3H6S A;  3K24 A;  3OVX A;  1TL9 A;  4YYV A;  3PRM A;  3BWK A;  2AVW A;  4FIP A;  4Q8G A;  1KXR A;  4N8W A;  1GMY A;  4X6H A;  2ATO A;  3KKU A;  2JRI A;  4RNA A;  1XKG A;  5JA7 A;  4RF0 A;  3E9S A;  2ARY A;  2FQ9 A;  1QMY A;  3ZNH A;  2FUD A;  3GCB A;  3PRP A;  3PBH A;  3B21 A;  3TRK A;  1CPJ A;  3QT4 A;  3O65 A;  1QXP A;  4REZ A;  2P7U A;  4CDD B;  2Y6E A;  2BTW A;  4N4Z A;  2FYE A;  3KSE A;  5CVN B;  1FH0 A;  3PHW A;  1AU0 A;  3CH3 X;  2YJC A;  3P5W A;  2DCA A;  2AIM A;  1MIR A;  5KO3 A;  1BGO A;  1PIP A;  4CDC B;  3BBA A;  4YYQ A;  1YVB A;  2PBH A;  1PPO A;  2DCC A;  1PXV A;  1U9W A;  1K3B B;  2F1G A;  7PCK A;  3BC3 A;  2OZ2 A;  3HD3 A;  4OW0 A;  4PP2 E;  5EZQ A;  1STF E;  4MZS A;  5E6J A;  1F29 A;  2DC6 A;  1ATK A;  5EZS A;  4BOQ A;  2AUZ A;  2PAD A;  1GEC E;  2FT2 A;  1VJV A;  5CHV A;  4CDE B;  4RY2 A;  2R6N A;  2AUX A;  4I05 A;  1A6R A;  2FTD A;  4HXD B;  1S4V A;  3BCN A;  2GHU A;  1F2B A;  3V6E A;  3ZUA A;  4BQV A;  3O0U A;  2OP3 A;  3C0R A;  1POP A;  2AGA A;  3MTV A;  1DF0 A;  4RKX A;  4CZW A;  4HWY A;  4MI7 A;  5CVM A;  3W30 A;  5CHT A;  4FK5 A;  1TLO A;  2YJB A;  3IEJ A;  3OVZ A;  1QOL A;  2WBF X;  3WXE A;  3D6S A;  4GUA A;  2R9M A;  3PNR A;  1YZB A;  2NQG A;  3B79 A;  4N79 A;  1Y08 A;  3USV A;  2P0R A;  1BP4 A;  2HHN A;  5CVO B;  2YJ8 A;  2R9F A;  2ACT A;  3K8U A;  3HWN A;  3DF0 A;  1CTE A;  1U5I A;  1KFU L;  4MM3 B;  1NPZ A;  4PAD A;  2P86 A;  5A24 A;  3IMA A;  2XU3 A;  3WXG A;  1KFX L;  2G7Y A;  4AXL A;  4I07 A;  1PBH A; 
#chains in the Genus database with same CATH homology
 1PVJ A;  4REZ A;  3PT2 A;  4BOS A;  4A5U A;  2BTW A;  5JZE A;  4BOZ A;  4IUM A;  3PHW A;  4WUR A;  4D8B A;  3TMP A;  5KO3 A;  2BU3 A;  4P16 A;  3BBA A;  4R3D A;  4M0W A;  2Z84 A;  2FE8 A;  3MP2 A;  4OW0 A;  5EZQ A;  4D8I A;  4BOU A;  2J7Q A;  3MJ5 A;  2UZJ A;  3IFU A;  3PHX A;  5E6J A;  5EZS A;  4BOQ A;  2BTW B;  4PT5 A;  2J7Q C;  4OVZ A;  4RF1 A;  3BY4 A;  3BB7 A;  4HXD B;  3PSE A;  1UKF A;  4D8E A;  3C0R A;  3PHU A;  2AGA A;  3MTV A;  4RKX A;  2JTC A;  4MI7 A;  2HWK A;  3W30 A;  4BOP A;  4XZX A;  3OQC A;  4GUA A;  1YZB A;  4OVZ B;  3PRM A;  3RNV A;  1DKI A;  2DOS A;  2JRI A;  4RNA A;  4RF0 A;  3W31 A;  3E9S A;  4IP3 A;  4MM3 B;  3ZNH A;  3PRP A;  3B21 A;  4ZTB A;  3TRK A;  3O65 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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