1NXUA

Crystal structure of e. coli hypothetical oxidoreductase yiak northeast structural genomics consortium target er82.
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
332
structure length
332
Chain Sequence
MKVTFEQLKAAFNRVLISRGVDSETADACAEMFARTTESGVYSHGVNRFPRFIQQLENGDIIPDAQPKRITSLGAIEQWDAQRSIGNLTAKKMMDRAIELAADHGIGLVALRNANHWMRGGSYGWQAAEKGYIGICWTNSIAVMPPWGAKECRIGTNPLIVAIPSTPITMVDMSMSMFSYGMLEVNRLAGRQLPVDGGFDDEGNLTKEPGVIEKNRRILPMGYWKGSGMSIVLDMIATLLSDGASVAEVTQDNSDEYGISQIFIAIEVDKLIDGPTRDAKLQRIMDYVTSAERADENQAIRLPGHEFTTLLAENRRNGITVDDSVWAKIQAL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Novel NAD-binding Protein Revealed by the Crystal Structure of 2,3-Diketo-L-gulonate Reductase (YiaK).
pubmed doi rcsb
molecule tags Structural genomics, oxidoreductase
source organism Escherichia coli
molecule keywords Hypothetical oxidoreductase yiaK
total genus 96
structure length 332
sequence length 332
chains with identical sequence B
ec nomenclature ec 1.1.1.130: 3-dehydro-L-gulonate 2-dehydrogenase.
pdb deposition date 2003-02-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02615 Ldh_2 Malate/L-lactate dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1530.10 Mainly Alpha Orthogonal Bundle Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 1nxuA01
3.30.60.50 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Hypothetical oxidoreductase yiak; domain 3 1nxuA03
3.30.1370.60 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 Hypothetical oxidoreductase yiak; domain 2 1nxuA02
4FJUA 1V9NA 1S20A 1XRHA 1WTJA 4FJSA 1NXUA 2CWFA 3UOEA 1Z2IA 2X06A 1X0AA 2CWHA 4H8AA 3I0PA 1VBIA 2G8YA
chains in the Genus database with same CATH superfamily
5J8FA 2UUAH 2E3UA 1UG8A 3JAMW 2NU3I 4LF7H 4JI1H 1FYBA 2MJHA 4OX9H 1XBTA 2XRCA 4AM3A 1HNWH 5DT9A 2QQEA 1M8BA 4GKKH 4LF5H 4KHPH 1WTJA 1H0ZA 2ARPF 2ANRA 4X64H 5C0XG 1CT4I 2LUYA 2JZXA 2K1HA 2UXCH 3GR5A 2SGDI 1N36H 2OVOA 1LR8A 1I6UA 2VQFH 1FKAH 2JE6I 4DR5H 4JI8H 4JI2H 4DV1H 4L9MA 2N71A 1AN7A 1HEVA 9WGAA 1Q9BA 2KCXA 1RFHA 2CWGA 5JHWC 1TBOA 5E3QA 2YQRA 2ELIA 4IFDG 2ZQEA 1P9ZA 1PTQA 4YY3H 3GABA 1J5EH 4MPIA 1XNRH 1V1HA 3RU0A 1HNZH 3PDNA 4OVOA 2PY9A 2CTJA 4LFCH 1I94H 4FKDA 4FJSA 2V53A 4AQYH 2CJSC 2W0TA 1W3SA 2UU9H 4E1RA 2YUUA 4AMLA 2E73A 3UEJA 2JA9A 1J5KA 1CGJI 2JVZA 2KMOA 3U1KA 2P2RA 4SGBI 4QMFB 2NU2I 1VBIA 4JI3H 1Z7KB 4JI5H 4WANA 2ODDA 4B3TH 4BA2I 2DIPA 1BUSA 1OYVI 1U5KA 3UOEA 2VQEH 4DV4H 1ZZKA 2DKVA 1K7TA 1X4SA 1N32H 2M5XA 5IT9W 4WP4A 2JZMA 5FUXA 3J81W 3TO9A 2GVIA 4AIMA 2VKCA 1V8CA 3J7AK 1KHMA 3R5DA 1FARA 2GIVA 2LRRA 2WVJA 1V1IA 2BUSA 1ULNA 3OVOA 3EZJA 4DV3H 3TOAA 4G08A 3QD7X 4UXJA 1Y1BA 2CTLA 4B3RH 1PQXA 2D9IA 1N13A 1AN1I 3VDPA 4JVYA 4E9JA 5FUYA 2HH2A 4JI6H 4OD6A 3TO6A 3VKEA 2CTFA 4PDBA 2PT7G 3GKUA 1OMTA 4NXMH 2ENNA 3UGDA 2CTKA 1OMUA 1XX6A 2RIJA 2UVOA 1CSOI 3OXLA 1DTJA 7WGAA 1EC6A 2N1AB 4NZTM 2NN6G 3UFFA 3MEKA 1TUSA 4B6DA 2QPOA 1ULKA 2F4VH 2J9RA 1CHOI 3R5BA 4LF6H 3VDUA 1TUAA 4HGUA 4JI4H 1Y1CA 3SEKC 4LF8H 2E5LH 4B3MH 4JI0H 1MJBA 2CPMA 5LMUH 2LB7A 3KDKA 4UXIA 2HHHH 4JCVE 3AEVB 2GKRI 1R0RI 4DUYH 1NXUA 3HH2C 1R79A 1WVNA 1ZTGA 3UGIA 2V1CC 3T1HH 4JI7H 2OZUA 2N52A 3SGQI 4WALA 2QQDA 4B8TA 4LF9H 2SGEI 1PTRA 4LFBH 2L8EA 2Y0MA 3R5AA 5DAEA 1X4NA 2V1CA 1IBLH 1WKXA 2JYYA 2JEBI 1N33H 1KBEA 3E59A 1TBNA 3NCVA 2FNFX 1V9NA 3CXLA 3KY9A 1K7VA 1VIHA 4GKJH 4X65H 4JVHA 1S20A 1VIGA 2ROWA 2M6QA 1HR0H 2KMPA 4JV5H 1SGNI 1FAQA 4NXNH 2X52A 1PCEA 3J80W 2UXBH 2DB6A 3V69A 4YHHH 1IY5A 2OD1A 2NU1I 1X0AA 2CWHA 4DV5H 4NBQA 4OO1G 1KMAA 5FUVA 1Z2IA 1TBRR 1TBQR 5FLXW 3TO7A 2SGFI 2CWFA 1IW4A 4JYAH 1ZZJA 1UHAA 2SGPI 2F3CI 1IBKH 2ENZA 2LTMA 2FPHX 1LR9A 3FC3A 2J87A 2JA1A 5EX0A 5LMNH 4DR4H 2L7XA 1OVOA 2OPUA 2G8YA 2KMQA 3OL0A 4DR6H 2OU2A 2LEOA 4GI3C 4B3SH 3B4VC 3R5CA 2NU0I 5J8CA 3D00A 5E3RA 2GKTI 3QTLD 1SGPI 2ORVA 2UZ3A 3E2IA 2QQCA 1CGII 2N17A 1TIHA 1IY6A 1IBMH 4DR7H 1WE8A 1WGTA 3OXGA 1P9GA 1SGRI 2B0UC 1X4MA 2LF0A 2CTEA 3FSXA 4EC5A 1DS2I 2E5RA 4DUZH 2P6AC 4DR2H 1MJAA 5A2QW 1HPTA 3RF2A 1WGCA 2PQUA 4LIJA 2ZM6H 2ERWA 4A24A 1MT1A 3TOBA 1FJGH 1DT4A 2QNDA 2DGRA 2CTMA 2ORWA 1Y8FA 1TGSI 4UXHA 5LL6b 2UUCH 2X3TA 4E1PA 2CPQA 2QQ0A 4X62H 1XMQH 4BA1I 1J4WA 1PPFI 2KMRA 3OETA 2B8TA 3UEYA 1VDDA 2VRWB 3OTOH 5EX3A 4FJUA 4B8CD 4DV0H 1PJUA 1SGDI 4DV2H 1SGEI 1UUCA 4LFAH 3T1YH 4K0KH 1MJ9A 2PQ8A 1X9ZA 2K9HA 2O4CA 2UXDH 5BR8H 3QWPA 2SGQI 3SB1A 1M8CA 1KBFA 2ANNA 4DNCA 1YTPA 4DR3H 5CCMA 5K36G 5CCLA 1HDLA 1WHRA 3KDGA 2RC4A 1CT0I 2JXDA 4NZRM 1DS3I 1TURA 2LTLA 3FAUA 1FY7A 1W4RA 4H8AA 4DR1H 1S03G 2AXYA 3VE5A 1ULMA 1X74A 5HQ8A 2Y3MA 1HNXH 2Z0SA 1MSZA 5FUWA 1N34H 1XMOH 3I0PA 1XNQH 2JW6A 3FSYA 1XRHA 3BJIA 2WGCA 2YQPA 2GKVA 1F0XA 2FFMA 1UVGA 1YU6C 5HI7A 2JEAI 3OSSD 1XA6A 2OPVA 2FMRA 3L7ZC 1CT2I 2WCYA 1SGYI 3TJQA 4DV7H 1TOTA 1HJAI 1ZZIA 2M8WA 2A20A 5JEAG 1CE3A 5IWAH 4LF4H 1ODHA 2NU4I 4OCHA 2HH3A 1NUBA 5E3PA 2A1SA 1SEIA 1BMOA 3OXFA 3UGLA 1LR7A 4DV6H 4X66H 1K1GA 3GOXA 3SGBI 2BA0A 3QAHA 2BL5A 1K7UA 2X06A 1UVFA 1SGQI 2UUBH
chains in the Genus database with same CATH topology
4FJUA 1V9NA 1S20A 1XRHA 1WTJA 4FJSA 1NXUA 2CWFA 3UOEA 1Z2IA 2X06A 1X0AA 2CWHA 4H8AA 3I0PA 1VBIA 2G8YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FJU A;  1V9N A;  1S20 A;  1XRH A;  1WTJ A;  4FJS A;  1NXU A;  2CWF A;  3UOE A;  1Z2I A;  2X06 A;  1X0A A;  2CWH A;  4H8A A;  3I0P A;  1VBI A;  2G8Y A; 
#chains in the Genus database with same CATH topology
 5J8F A;  2UUA H;  2E3U A;  1UG8 A;  3JAM W;  2NU3 I;  4LF7 H;  4JI1 H;  1FYB A;  2MJH A;  4OX9 H;  1XBT A;  2XRC A;  4AM3 A;  1HNW H;  5DT9 A;  2QQE A;  1M8B A;  4GKK H;  4LF5 H;  4KHP H;  1WTJ A;  1H0Z A;  2ARP F;  2ANR A;  4X64 H;  5C0X G;  1CT4 I;  2LUY A;  2JZX A;  2K1H A;  2UXC H;  3GR5 A;  2SGD I;  1N36 H;  2OVO A;  1LR8 A;  1I6U A;  2VQF H;  1FKA H;  2JE6 I;  4DR5 H;  4JI8 H;  4JI2 H;  4DV1 H;  4L9M A;  2N71 A;  1AN7 A;  1HEV A;  9WGA A;  1Q9B A;  2KCX A;  1RFH A;  2CWG A;  5JHW C;  1TBO A;  5E3Q A;  2YQR A;  2ELI A;  4IFD G;  2ZQE A;  1P9Z A;  1PTQ A;  4YY3 H;  3GAB A;  1J5E H;  4MPI A;  1XNR H;  1V1H A;  3RU0 A;  1HNZ H;  3PDN A;  4OVO A;  2PY9 A;  2CTJ A;  4LFC H;  1I94 H;  4FKD A;  4FJS A;  2V53 A;  4AQY H;  2CJS C;  2W0T A;  1W3S A;  2UU9 H;  4E1R A;  2YUU A;  4AML A;  2E73 A;  3UEJ A;  2JA9 A;  1J5K A;  1CGJ I;  2JVZ A;  2KMO A;  3U1K A;  2P2R A;  4SGB I;  4QMF B;  2NU2 I;  1VBI A;  4JI3 H;  1Z7K B;  4JI5 H;  4WAN A;  2ODD A;  4B3T H;  4BA2 I;  2DIP A;  1BUS A;  1OYV I;  1U5K A;  3UOE A;  2VQE H;  4DV4 H;  1ZZK A;  2DKV A;  1K7T A;  1X4S A;  1N32 H;  2M5X A;  5IT9 W;  4WP4 A;  2JZM A;  5FUX A;  3J81 W;  3TO9 A;  2GVI A;  4AIM A;  2VKC A;  1V8C A;  3J7A K;  1KHM A;  3R5D A;  1FAR A;  2GIV A;  2LRR A;  2WVJ A;  1V1I A;  2BUS A;  1ULN A;  3OVO A;  3EZJ A;  4DV3 H;  3TOA A;  4G08 A;  3QD7 X;  4UXJ A;  1Y1B A;  2CTL A;  4B3R H;  1PQX A;  2D9I A;  1N13 A;  1AN1 I;  3VDP A;  4JVY A;  4E9J A;  5FUY A;  2HH2 A;  4JI6 H;  4OD6 A;  3TO6 A;  3VKE A;  2CTF A;  4PDB A;  2PT7 G;  3GKU A;  1OMT A;  4NXM H;  2ENN A;  3UGD A;  2CTK A;  1OMU A;  1XX6 A;  2RIJ A;  2UVO A;  1CSO I;  3OXL A;  1DTJ A;  7WGA A;  1EC6 A;  2N1A B;  4NZT M;  2NN6 G;  3UFF A;  3MEK A;  1TUS A;  4B6D A;  2QPO A;  1ULK A;  2F4V H;  2J9R A;  1CHO I;  3R5B A;  4LF6 H;  3VDU A;  1TUA A;  4HGU A;  4JI4 H;  1Y1C A;  3SEK C;  4LF8 H;  2E5L H;  4B3M H;  4JI0 H;  1MJB A;  2CPM A;  5LMU H;  2LB7 A;  3KDK A;  4UXI A;  2HHH H;  4JCV E;  3AEV B;  2GKR I;  1R0R I;  4DUY H;  1NXU A;  3HH2 C;  1R79 A;  1WVN A;  1ZTG A;  3UGI A;  2V1C C;  3T1H H;  4JI7 H;  2OZU A;  2N52 A;  3SGQ I;  4WAL A;  2QQD A;  4B8T A;  4LF9 H;  2SGE I;  1PTR A;  4LFB H;  2L8E A;  2Y0M A;  3R5A A;  5DAE A;  1X4N A;  2V1C A;  1IBL H;  1WKX A;  2JYY A;  2JEB I;  1N33 H;  1KBE A;  3E59 A;  1TBN A;  3NCV A;  2FNF X;  1V9N A;  3CXL A;  3KY9 A;  1K7V A;  1VIH A;  4GKJ H;  4X65 H;  4JVH A;  1S20 A;  1VIG A;  2ROW A;  2M6Q A;  1HR0 H;  2KMP A;  4JV5 H;  1SGN I;  1FAQ A;  4NXN H;  2X52 A;  1PCE A;  3J80 W;  2UXB H;  2DB6 A;  3V69 A;  4YHH H;  1IY5 A;  2OD1 A;  2NU1 I;  1X0A A;  2CWH A;  4DV5 H;  4NBQ A;  4OO1 G;  1KMA A;  5FUV A;  1Z2I A;  1TBR R;  1TBQ R;  5FLX W;  3TO7 A;  2SGF I;  2CWF A;  1IW4 A;  4JYA H;  1ZZJ A;  1UHA A;  2SGP I;  2F3C I;  1IBK H;  2ENZ A;  2LTM A;  2FPH X;  1LR9 A;  3FC3 A;  2J87 A;  2JA1 A;  5EX0 A;  5LMN H;  4DR4 H;  2L7X A;  1OVO A;  2OPU A;  2G8Y A;  2KMQ A;  3OL0 A;  4DR6 H;  2OU2 A;  2LEO A;  4GI3 C;  4B3S H;  3B4V C;  3R5C A;  2NU0 I;  5J8C A;  3D00 A;  5E3R A;  2GKT I;  3QTL D;  1SGP I;  2ORV A;  2UZ3 A;  3E2I A;  2QQC A;  1CGI I;  2N17 A;  1TIH A;  1IY6 A;  1IBM H;  4DR7 H;  1WE8 A;  1WGT A;  3OXG A;  1P9G A;  1SGR I;  2B0U C;  1X4M A;  2LF0 A;  2CTE A;  3FSX A;  4EC5 A;  1DS2 I;  2E5R A;  4DUZ H;  2P6A C;  4DR2 H;  1MJA A;  5A2Q W;  1HPT A;  3RF2 A;  1WGC A;  2PQU A;  4LIJ A;  2ZM6 H;  2ERW A;  4A24 A;  1MT1 A;  3TOB A;  1FJG H;  1DT4 A;  2QND A;  2DGR A;  2CTM A;  2ORW A;  1Y8F A;  1TGS I;  4UXH A;  5LL6 b;  2UUC H;  2X3T A;  4E1P A;  2CPQ A;  2QQ0 A;  4X62 H;  1XMQ H;  4BA1 I;  1J4W A;  1PPF I;  2KMR A;  3OET A;  2B8T A;  3UEY A;  1VDD A;  2VRW B;  3OTO H;  5EX3 A;  4FJU A;  4B8C D;  4DV0 H;  1PJU A;  1SGD I;  4DV2 H;  1SGE I;  1UUC A;  4LFA H;  3T1Y H;  4K0K H;  1MJ9 A;  2PQ8 A;  1X9Z A;  2K9H A;  2O4C A;  2UXD H;  5BR8 H;  3QWP A;  2SGQ I;  3SB1 A;  1M8C A;  1KBF A;  2ANN A;  4DNC A;  1YTP A;  4DR3 H;  5CCM A;  5K36 G;  5CCL A;  1HDL A;  1WHR A;  3KDG A;  2RC4 A;  1CT0 I;  2JXD A;  4NZR M;  1DS3 I;  1TUR A;  2LTL A;  3FAU A;  1FY7 A;  1W4R A;  4H8A A;  4DR1 H;  1S03 G;  2AXY A;  3VE5 A;  1ULM A;  1X74 A;  5HQ8 A;  2Y3M A;  1HNX H;  2Z0S A;  1MSZ A;  5FUW A;  1N34 H;  1XMO H;  3I0P A;  1XNQ H;  2JW6 A;  3FSY A;  1XRH A;  3BJI A;  2WGC A;  2YQP A;  2GKV A;  1F0X A;  2FFM A;  1UVG A;  1YU6 C;  5HI7 A;  2JEA I;  3OSS D;  1XA6 A;  2OPV A;  2FMR A;  3L7Z C;  1CT2 I;  2WCY A;  1SGY I;  3TJQ A;  4DV7 H;  1TOT A;  1HJA I;  1ZZI A;  2M8W A;  2A20 A;  5JEA G;  1CE3 A;  5IWA H;  4LF4 H;  1ODH A;  2NU4 I;  4OCH A;  2HH3 A;  1NUB A;  5E3P A;  2A1S A;  1SEI A;  1BMO A;  3OXF A;  3UGL A;  1LR7 A;  4DV6 H;  4X66 H;  1K1G A;  3GOX A;  3SGB I;  2BA0 A;  3QAH A;  2BL5 A;  1K7U A;  2X06 A;  1UVF A;  1SGQ I;  2UUB H; 
#chains in the Genus database with same CATH homology
 4FJU A;  1V9N A;  1S20 A;  1XRH A;  1WTJ A;  4FJS A;  1NXU A;  2CWF A;  3UOE A;  1Z2I A;  2X06 A;  1X0A A;  2CWH A;  4H8A A;  3I0P A;  1VBI A;  2G8Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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