1NXUA

Crystal structure of e. coli hypothetical oxidoreductase yiak northeast structural genomics consortium target er82.
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
332
structure length
332
Chain Sequence
MKVTFEQLKAAFNRVLISRGVDSETADACAEMFARTTESGVYSHGVNRFPRFIQQLENGDIIPDAQPKRITSLGAIEQWDAQRSIGNLTAKKMMDRAIELAADHGIGLVALRNANHWMRGGSYGWQAAEKGYIGICWTNSIAVMPPWGAKECRIGTNPLIVAIPSTPITMVDMSMSMFSYGMLEVNRLAGRQLPVDGGFDDEGNLTKEPGVIEKNRRILPMGYWKGSGMSIVLDMIATLLSDGASVAEVTQDNSDEYGISQIFIAIEVDKLIDGPTRDAKLQRIMDYVTSAERADENQAIRLPGHEFTTLLAENRRNGITVDDSVWAKIQAL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Novel NAD-binding Protein Revealed by the Crystal Structure of 2,3-Diketo-L-gulonate Reductase (YiaK).
pubmed doi rcsb
molecule tags Structural genomics, oxidoreductase
source organism Escherichia coli
molecule keywords Hypothetical oxidoreductase yiaK
total genus 96
structure length 332
sequence length 332
chains with identical sequence B
ec nomenclature ec 1.1.1.130: 3-dehydro-L-gulonate 2-dehydrogenase.
pdb deposition date 2003-02-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02615 Ldh_2 Malate/L-lactate dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1530.10 Mainly Alpha Orthogonal Bundle Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 1nxuA01
3.30.60.50 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Hypothetical oxidoreductase yiak; domain 3 1nxuA03
3.30.1370.60 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 Hypothetical oxidoreductase yiak; domain 2 1nxuA02
1XRHA 2G8YA 3I0PA 1VBIA 1V9NA 4FJUA 1X0AA 2CWHA 1NXUA 1Z2IA 2CWFA 1S20A 1WTJA 2X06A 3UOEA 4H8AA 4FJSA
chains in the Genus database with same CATH superfamily
1XRHA 2OU2A 1VBIA 3FSXA 4E1PA 2HHHH 1PJUA 2N17A 4DV1H 1PTRA 3VKEA 1KBFA 2PQUA 4B6DA 1FAQA 2J87A 1HNXH 2ANRA 1XMQH 4WANA 1CGJI 1X0AA 2K9HA 4DR3H 5A2QW 2CPMA 1CHOI 3UGLA 1MT1A 2PQ8A 1Y1CA 5C0XG 1N36H 2UXDH 2UUBH 3AEVB 9WGAA 2CPQA 2N52A 4JI5H 2SGPI 4EC5A 1LR8A 5E3RA 2LRRA 3HH2C 2BA0A 1WTJA 4DR4H 4JVHA 4HGUA 4B3TH 2SGEI 3OXGA 3OXLA 1R0RI 2Z0SA 2X3TA 4G08A 4LFCH 1OMTA 5FUXA 4YY3H 2NU4I 3RF2A 4KHPH 1OYVI 1NXUA 1IBMH 1WE8A 1PQXA 1V8CA 4LF4H 2J9RA 2VQEH 3TOBA 5E3PA 4NZRM 1RFHA 1K7VA 5HQ8A 1MJAA 3OL0A 1XBTA 2KCXA 3T1YH 4PDBA 2CTLA 4FJSA 4FKDA 2JVZA 2WVJA 1SGDI 3SGQI 4K0KH 1LR9A 1YU6C 1WGTA 3D00A 4E9JA 2JA9A 2OZUA 2ELIA 2CWGA 1P9GA 2BL5A 1TIHA 3QTLD 1HNZH 4DR6H 3TO7A 1BUSA 2UUAH 3VDUA 5LMNH 2L8EA 4X64H 2KMQA 2CWFA 1J4WA 4JI1H 1AN1I 2HH3A 4SGBI 3OSSD 4LF9H 1FJGH 1OVOA 3QAHA 3FAUA 5IT9W 3VDPA 2FFMA 2MJHA 4LF6H 2UXCH 1HNWH 4OVOA 3JAMW 3J80W 2CTJA 1MJ9A 5DT9A 1N32H 2ODDA 1VDDA 4MPIA 3FC3A 4JI4H 4JI0H 5E3QA 2ORVA 3RU0A 2V53A 4JI3H 3EZJA 1NUBA 3T1HH 4LF7H 1ULKA 5J8CA 1HDLA 2LB7A 4OX9H 5FUWA 1F0XA 4NXMH 2CTMA 2QQCA 2FPHX 4B8TA 5K36G 4AQYH 1HJAI 1FYBA 5FUYA 2GIVA 5JEAG 2A1SA 2OPVA 1IW4A 2SGFI 2E73A 3UFFA 2OD1A 3V69A 3UEJA 2LUYA 5EX3A 1CT4I 4BA2I 1K1GA 4LF8H 1WKXA 1J5EH 3OXFA 4AIMA 2GKRI 2QNDA 1N13A 3OVOA 2JZXA 1X74A 2B8TA 1U5KA 4LIJA 1TUSA 3PDNA 5CCLA 2JEAI 1VIHA 2GKVA 5CCMA 1TBQR 2UXBH 4E1RA 2X52A 2NU0I 1OMUA 7WGAA 4DR2H 2UVOA 4DNCA 2YUUA 1TBOA 2KMOA 1LR7A 2A20A 2DGRA 2ZM6H 4JV5H 1W3SA 4A24A 2M6QA 2NN6G 2E5LH 4OO1G 1PCEA 1XMOH 1WVNA 2HH2A 4JI6H 2SGDI 5JHWC 3QWPA 3TO6A 1ZZJA 2ENZA 2NU3I 4B3SH 2ENNA 1FKAH 1V1HA 1H0ZA 2G8YA 2CTFA 1XX6A 3SB1A 4JI8H 1UUCA 2N71A 2M8WA 2DB6A 4NZTM 1MJBA 1TBNA 4DR5H 3OETA 3B4VC 1I94H 2PY9A 2VRWB 2ARPF 3J7AK 1VIGA 3GKUA 4DV7H 3UGDA 1SGEI 2YQRA 2E3UA 2JEBI 4JYAH 5FUVA 2VQFH 2NU2I 2ERWA 3SGBI 2D9IA 2ZQEA 4DV0H 1UVFA 5J8FA 2JA1A 4UXIA 1ZZKA 2QQEA 1IBLH 3E2IA 1ZTGA 4DR7H 4B8CD 4JVYA 2XRCA 2ANNA 1UHAA 2PT7G 1PPFI 1KBEA 3R5BA 4L9MA 5DAEA 2ORWA 2UZ3A 4X62H 1EC6A 2JZMA 2WCYA 1FY7A 1DTJA 4JCVE 1TOTA 1HPTA 4IFDG 2V1CC 2Y0MA 5HI7A 3FSYA 2F3CI 4DV2H 3NCVA 3KDKA 4LFAH 2LTLA 2LTMA 2RC4A 1MSZA 2GVIA 2N1AB 2CTKA 4DV6H 2QPOA 2OPUA 4UXJA 1ULNA 5FLXW 4GI3C 4DV4H 4JI2H 4DR1H 1V1IA 1CT0I 3VE5A 1ODHA 1CSOI 1DS2I 1Y8FA 2SGQI 1X4NA 2Y3MA 2AXYA 4QMFB 2FNFX 4DUZH 4OCHA 2DIPA 2X06A 3UOEA 1DT4A 3OTOH 2O4CA 2M5XA 3L7ZC 1P9ZA 1FARA 1S03G 1SGQI 3R5DA 2GKTI 1CGII 4AMLA 3TJQA 2QQ0A 1YTPA 1S20A 4DUYH 4DV3H 1XNQH 1DS3I 1KMAA 2VKCA 5LL6b 2BUSA 2CWHA 3GR5A 1SGPI 1J5KA 2E5RA 2KMRA 2CJSC 4BA1I 1IY6A 1M8BA 1TURA 1SGNI 1CE3A 2B0UC 2L7XA 1X4SA 1HEVA 1X9ZA 4LFBH 1W4RA 1R79A 2K1HA 3SEKC 4GKKH 2P6AC 2V1CA 2NU1I 2YQPA 1UG8A 3R5AA 1XNRH 1Z2IA 2ROWA 1Q9BA 1BMOA 2FMRA 2JE6I 2UUCH 1TUAA 1KHMA 5BR8H 3KY9A 4GKJH 1N33H 2JXDA 1TBRR 1N34H 5EX0A 1M8CA 3QD7X 2CTEA 2QQDA 3UGIA 2W0TA 2P2RA 1XA6A 1SEIA 1IY5A 4B3MH 2WGCA 3R5CA 4UXHA 1WGCA 3I0PA 3J81W 4X65H 4FJUA 3U1KA 3E59A 1UVGA 1AN7A 4NXNH 3UEYA 1I6UA 4NBQA 2RIJA 3GOXA 4WP4A 1PTQA 1Z7KB 2KMPA 3CXLA 1CT2I 2UU9H 1K7UA 3MEKA 3KDGA 1ZZIA 1Y1BA 1X4MA 4YHHH 1HR0H 2OVOA 2JW6A 4WALA 1V9NA 1SGRI 4JI7H 3BJIA 4DV5H 5LMUH 4AM3A 2LEOA 2DKVA 3TOAA 3GABA 4B3RH 5IWAH 2F4VH 1ULMA 1SGYI 2LF0A 1WHRA 4LF5H 3TO9A 1IBKH 1TGSI 4X66H 2JYYA 4H8AA 4OD6A 1K7TA
chains in the Genus database with same CATH topology
1XRHA 2G8YA 3I0PA 1VBIA 1V9NA 4FJUA 1X0AA 2CWHA 1NXUA 1Z2IA 2CWFA 1S20A 1WTJA 2X06A 3UOEA 4H8AA 4FJSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XRH A;  2G8Y A;  3I0P A;  1VBI A;  1V9N A;  4FJU A;  1X0A A;  2CWH A;  1NXU A;  1Z2I A;  2CWF A;  1S20 A;  1WTJ A;  2X06 A;  3UOE A;  4H8A A;  4FJS A; 
#chains in the Genus database with same CATH topology
 1XRH A;  2OU2 A;  1VBI A;  3FSX A;  4E1P A;  2HHH H;  1PJU A;  2N17 A;  4DV1 H;  1PTR A;  3VKE A;  1KBF A;  2PQU A;  4B6D A;  1FAQ A;  2J87 A;  1HNX H;  2ANR A;  1XMQ H;  4WAN A;  1CGJ I;  1X0A A;  2K9H A;  4DR3 H;  5A2Q W;  2CPM A;  1CHO I;  3UGL A;  1MT1 A;  2PQ8 A;  1Y1C A;  5C0X G;  1N36 H;  2UXD H;  2UUB H;  3AEV B;  9WGA A;  2CPQ A;  2N52 A;  4JI5 H;  2SGP I;  4EC5 A;  1LR8 A;  5E3R A;  2LRR A;  3HH2 C;  2BA0 A;  1WTJ A;  4DR4 H;  4JVH A;  4HGU A;  4B3T H;  2SGE I;  3OXG A;  3OXL A;  1R0R I;  2Z0S A;  2X3T A;  4G08 A;  4LFC H;  1OMT A;  5FUX A;  4YY3 H;  2NU4 I;  3RF2 A;  4KHP H;  1OYV I;  1NXU A;  1IBM H;  1WE8 A;  1PQX A;  1V8C A;  4LF4 H;  2J9R A;  2VQE H;  3TOB A;  5E3P A;  4NZR M;  1RFH A;  1K7V A;  5HQ8 A;  1MJA A;  3OL0 A;  1XBT A;  2KCX A;  3T1Y H;  4PDB A;  2CTL A;  4FJS A;  4FKD A;  2JVZ A;  2WVJ A;  1SGD I;  3SGQ I;  4K0K H;  1LR9 A;  1YU6 C;  1WGT A;  3D00 A;  4E9J A;  2JA9 A;  2OZU A;  2ELI A;  2CWG A;  1P9G A;  2BL5 A;  1TIH A;  3QTL D;  1HNZ H;  4DR6 H;  3TO7 A;  1BUS A;  2UUA H;  3VDU A;  5LMN H;  2L8E A;  4X64 H;  2KMQ A;  2CWF A;  1J4W A;  4JI1 H;  1AN1 I;  2HH3 A;  4SGB I;  3OSS D;  4LF9 H;  1FJG H;  1OVO A;  3QAH A;  3FAU A;  5IT9 W;  3VDP A;  2FFM A;  2MJH A;  4LF6 H;  2UXC H;  1HNW H;  4OVO A;  3JAM W;  3J80 W;  2CTJ A;  1MJ9 A;  5DT9 A;  1N32 H;  2ODD A;  1VDD A;  4MPI A;  3FC3 A;  4JI4 H;  4JI0 H;  5E3Q A;  2ORV A;  3RU0 A;  2V53 A;  4JI3 H;  3EZJ A;  1NUB A;  3T1H H;  4LF7 H;  1ULK A;  5J8C A;  1HDL A;  2LB7 A;  4OX9 H;  5FUW A;  1F0X A;  4NXM H;  2CTM A;  2QQC A;  2FPH X;  4B8T A;  5K36 G;  4AQY H;  1HJA I;  1FYB A;  5FUY A;  2GIV A;  5JEA G;  2A1S A;  2OPV A;  1IW4 A;  2SGF I;  2E73 A;  3UFF A;  2OD1 A;  3V69 A;  3UEJ A;  2LUY A;  5EX3 A;  1CT4 I;  4BA2 I;  1K1G A;  4LF8 H;  1WKX A;  1J5E H;  3OXF A;  4AIM A;  2GKR I;  2QND A;  1N13 A;  3OVO A;  2JZX A;  1X74 A;  2B8T A;  1U5K A;  4LIJ A;  1TUS A;  3PDN A;  5CCL A;  2JEA I;  1VIH A;  2GKV A;  5CCM A;  1TBQ R;  2UXB H;  4E1R A;  2X52 A;  2NU0 I;  1OMU A;  7WGA A;  4DR2 H;  2UVO A;  4DNC A;  2YUU A;  1TBO A;  2KMO A;  1LR7 A;  2A20 A;  2DGR A;  2ZM6 H;  4JV5 H;  1W3S A;  4A24 A;  2M6Q A;  2NN6 G;  2E5L H;  4OO1 G;  1PCE A;  1XMO H;  1WVN A;  2HH2 A;  4JI6 H;  2SGD I;  5JHW C;  3QWP A;  3TO6 A;  1ZZJ A;  2ENZ A;  2NU3 I;  4B3S H;  2ENN A;  1FKA H;  1V1H A;  1H0Z A;  2G8Y A;  2CTF A;  1XX6 A;  3SB1 A;  4JI8 H;  1UUC A;  2N71 A;  2M8W A;  2DB6 A;  4NZT M;  1MJB A;  1TBN A;  4DR5 H;  3OET A;  3B4V C;  1I94 H;  2PY9 A;  2VRW B;  2ARP F;  3J7A K;  1VIG A;  3GKU A;  4DV7 H;  3UGD A;  1SGE I;  2YQR A;  2E3U A;  2JEB I;  4JYA H;  5FUV A;  2VQF H;  2NU2 I;  2ERW A;  3SGB I;  2D9I A;  2ZQE A;  4DV0 H;  1UVF A;  5J8F A;  2JA1 A;  4UXI A;  1ZZK A;  2QQE A;  1IBL H;  3E2I A;  1ZTG A;  4DR7 H;  4B8C D;  4JVY A;  2XRC A;  2ANN A;  1UHA A;  2PT7 G;  1PPF I;  1KBE A;  3R5B A;  4L9M A;  5DAE A;  2ORW A;  2UZ3 A;  4X62 H;  1EC6 A;  2JZM A;  2WCY A;  1FY7 A;  1DTJ A;  4JCV E;  1TOT A;  1HPT A;  4IFD G;  2V1C C;  2Y0M A;  5HI7 A;  3FSY A;  2F3C I;  4DV2 H;  3NCV A;  3KDK A;  4LFA H;  2LTL A;  2LTM A;  2RC4 A;  1MSZ A;  2GVI A;  2N1A B;  2CTK A;  4DV6 H;  2QPO A;  2OPU A;  4UXJ A;  1ULN A;  5FLX W;  4GI3 C;  4DV4 H;  4JI2 H;  4DR1 H;  1V1I A;  1CT0 I;  3VE5 A;  1ODH A;  1CSO I;  1DS2 I;  1Y8F A;  2SGQ I;  1X4N A;  2Y3M A;  2AXY A;  4QMF B;  2FNF X;  4DUZ H;  4OCH A;  2DIP A;  2X06 A;  3UOE A;  1DT4 A;  3OTO H;  2O4C A;  2M5X A;  3L7Z C;  1P9Z A;  1FAR A;  1S03 G;  1SGQ I;  3R5D A;  2GKT I;  1CGI I;  4AML A;  3TJQ A;  2QQ0 A;  1YTP A;  1S20 A;  4DUY H;  4DV3 H;  1XNQ H;  1DS3 I;  1KMA A;  2VKC A;  5LL6 b;  2BUS A;  2CWH A;  3GR5 A;  1SGP I;  1J5K A;  2E5R A;  2KMR A;  2CJS C;  4BA1 I;  1IY6 A;  1M8B A;  1TUR A;  1SGN I;  1CE3 A;  2B0U C;  2L7X A;  1X4S A;  1HEV A;  1X9Z A;  4LFB H;  1W4R A;  1R79 A;  2K1H A;  3SEK C;  4GKK H;  2P6A C;  2V1C A;  2NU1 I;  2YQP A;  1UG8 A;  3R5A A;  1XNR H;  1Z2I A;  2ROW A;  1Q9B A;  1BMO A;  2FMR A;  2JE6 I;  2UUC H;  1TUA A;  1KHM A;  5BR8 H;  3KY9 A;  4GKJ H;  1N33 H;  2JXD A;  1TBR R;  1N34 H;  5EX0 A;  1M8C A;  3QD7 X;  2CTE A;  2QQD A;  3UGI A;  2W0T A;  2P2R A;  1XA6 A;  1SEI A;  1IY5 A;  4B3M H;  2WGC A;  3R5C A;  4UXH A;  1WGC A;  3I0P A;  3J81 W;  4X65 H;  4FJU A;  3U1K A;  3E59 A;  1UVG A;  1AN7 A;  4NXN H;  3UEY A;  1I6U A;  4NBQ A;  2RIJ A;  3GOX A;  4WP4 A;  1PTQ A;  1Z7K B;  2KMP A;  3CXL A;  1CT2 I;  2UU9 H;  1K7U A;  3MEK A;  3KDG A;  1ZZI A;  1Y1B A;  1X4M A;  4YHH H;  1HR0 H;  2OVO A;  2JW6 A;  4WAL A;  1V9N A;  1SGR I;  4JI7 H;  3BJI A;  4DV5 H;  5LMU H;  4AM3 A;  2LEO A;  2DKV A;  3TOA A;  3GAB A;  4B3R H;  5IWA H;  2F4V H;  1ULM A;  1SGY I;  2LF0 A;  1WHR A;  4LF5 H;  3TO9 A;  1IBK H;  1TGS I;  4X66 H;  2JYY A;  4H8A A;  4OD6 A;  1K7T A; 
#chains in the Genus database with same CATH homology
 1XRH A;  2G8Y A;  3I0P A;  1VBI A;  1V9N A;  4FJU A;  1X0A A;  2CWH A;  1NXU A;  1Z2I A;  2CWF A;  1S20 A;  1WTJ A;  2X06 A;  3UOE A;  4H8A A;  4FJS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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