2CWFA

Crystal structure of delta1-piperideine-2-carboxylate reductase from pseudomonas syringae complexed with nadph
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
332
structure length
332
Chain Sequence
TQTVSYPQLIDLLRRIFVVHGTSPEVADVLAENCASAQRDGSHSHGIFRIPGYLSSLASGWVDGKAVPVVEDVGAAFVRVDACNGFAQPALAAARSLLIDKARSAGVAILAIRGSHHFAALWPDVEPFAEQGLVALSMVNSMTCVVPHGARQPLFGTNPIAFGAPRAGGEPIVFDLATSAIAHGDVQIAAREGRLLPAGMGVDRDGLPTQEPRAILDGGALLPFGGHKGSALSMMVELLAAGLTGGNFSFEFDWSKHPGAQTPWTGQLLIVIDPDKGAGQHFAQRSEELVRQLHGVGQERLPGDRRYLERARSMAHGIVIAQADLERLQELA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of Delta1-piperideine-2-carboxylate/Delta1-pyrroline-2-carboxylate reductase belonging to a new family of NAD(P)H-dependent oxidoreductases: conformational change, substrate recognition, and stereochemistry of the reaction
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Pseudomonas syringae pv. tomato
molecule keywords delta1-piperideine-2-carboxylate reductase
total genus 113
structure length 332
sequence length 332
chains with identical sequence B
ec nomenclature ec 1.4.1.17: N-methylalanine dehydrogenase.
pdb deposition date 2005-06-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02615 Ldh_2 Malate/L-lactate dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1530.10 Mainly Alpha Orthogonal Bundle Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 2cwfA01
3.30.60.50 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Hypothetical oxidoreductase yiak; domain 3 2cwfA03
3.30.1370.60 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8; Chain: A, domain 1 Hypothetical oxidoreductase yiak; domain 2 2cwfA02
1Z2IA 2CWHA 2CWFA 2X06A 3I0PA 1XRHA 4FJUA 1V9NA 1NXUA 4H8AA 1VBIA 1S20A 3UOEA 2G8YA 4FJSA 1X0AA 1WTJA
chains in the Genus database with same CATH superfamily
2LF0A 1ZZJA 2CTJA 2ZM6H 1MJAA 2LEOA 2LTMA 2PT7G 4JI2H 1SGQI 2FFMA 1RFHA 3GABA 1I6UA 3I0PA 2VQEH 1ZZKA 2FMRA 4SGBI 5FUXA 4DV3H 4DV7H 2BA0A 3NCVA 1FY7A 2KMOA 1EC6A 2B8TA 2X06A 1PJUA 1XNRH 1K7UA 4JI1H 1CSOI 1PTQA 3FAUA 4NBQA 5JHWC 1DS2I 2NU0I 4JVYA 3OTOH 2CWFA 1MJ9A 1VIGA 2DKVA 1ZTGA 1AN1I 4LFBH 2F4VH 1Q9BA 4EC5A 2UUCH 4JVHA 5IT9W 5FUWA 3TO6A 1NUBA 4MPIA 3V69A 4LF9H 4UXJA 2ELIA 1TBOA 3SEKC 3TJQA 1HDLA 1CT2I 2CPQA 4JI5H 3QWPA 2UXBH 3TOBA 4X64H 1WE8A 1Y1BA 2CWHA 3OXLA 4NZRM 2KMQA 5CCLA 4B3MH 4BA1I 1LR8A 1K1GA 4B6DA 4LF5H 3UEJA 2JE6I 4JI4H 2OZUA 1IY6A 1H0ZA 1M8CA 4BA2I 2GKTI 2OD1A 2HH2A 2RC4A 1IY5A 2WCYA 4QMFB 1SGRI 2ENNA 3CXLA 5FUVA 4A24A 4DR4H 1MT1A 4AQYH 1TBNA 3SGQI 4JI3H 1CE3A 1VBIA 2JZMA 1X4NA 2X52A 4FKDA 2K1HA 1KBFA 2OPVA 1DTJA 4LF8H 1KBEA 5EX0A 1S20A 1CGII 4DV2H 1K7VA 2CPMA 1J5EH 3J7AK 1HR0H 4LF7H 2JVZA 4DR3H 2M8WA 4AM3A 2O4CA 1UVGA 1J5KA 1X4MA 3B4VC 4GKJH 1VIHA 2JW6A 1R0RI 3UGLA 2DGRA 2ARPF 3PDNA 2NU2I 4DUYH 3OETA 1OMUA 2WGCA 1ULMA 2JXDA 1Z2IA 5C0XG 1Z7KB 4B8CD 2Y3MA 5IWAH 1CT4I 4E1PA 1Y8FA 2V1CA 1N32H 2YQPA 2FNFX 1MSZA 2N1AB 2F3CI 2DB6A 2J87A 2L8EA 1W3SA 5LMNH 4E1RA 2FPHX 5JEAG 2E5RA 4LFCH 3OXFA 1PTRA 4OD6A 1TUAA 3TO7A 2SGPI 2CTKA 4LF6H 4NXMH 1YTPA 1TBQR 1K7TA 4DR2H 3OXGA 1FYBA 3VDUA 1AN7A 5E3RA 4X62H 1IBKH 1TBRR 3AEVB 4B3TH 2ORWA 1N36H 4JI0H 4AMLA 5K36G 3L7ZC 1SEIA 1HPTA 3VDPA 2QPOA 2QQDA 2CTMA 2CTLA 1TUSA 1OMTA 4LF4H 3KY9A 1TIHA 4JI8H 2SGQI 1ULNA 4DV0H 2YQRA 2P2RA 3RF2A 4DR6H 1PCEA 5DT9A 2JEAI 1WKXA 4FJUA 3SB1A 4G08A 3TO9A 2QQ0A 1V1IA 2DIPA 4JI7H 2OVOA 1PPFI 1U5KA 1XBTA 2LRRA 3R5AA 5CCMA 1XA6A 2HH3A 4DV1H 4X66H 5J8CA 3JAMW 2GKRI 1UHAA 2BUSA 5FLXW 1DS3I 2GVIA 2LUYA 2G8YA 2ANRA 5J8FA 3GR5A 2ENZA 1IBLH 3UGDA 1HJAI 2E3UA 2MJHA 3UGIA 1WGTA 2VRWB 3QD7X 1SGDI 1FKAH 2Y0MA 3U1KA 1P9ZA 1J4WA 2GKVA 2JZXA 5LMUH 2SGFI 3J81W 3FSXA 4JYAH 2JA9A 2NU4I 4DV5H 3VE5A 2L7XA 1XMQH 4IFDG 2N17A 5HI7A 2UVOA 4HGUA 3KDKA 3FC3A 4GKKH 2ZQEA 4YHHH 2LB7A 4AIMA 2QNDA 3KDGA 2VQFH 2LTLA 4OVOA 1XRHA 2J9RA 1V9NA 4DR5H 1X74A 4L9MA 1WHRA 3D00A 4NZTM 1SGYI 2OU2A 3E59A 2UUBH 1XNQH 2X3TA 1SGEI 2P6AC 4KHPH 2ORVA 1N13A 3GKUA 2D9IA 4DR7H 1HNWH 3EZJA 4WP4A 1ZZIA 4LFAH 1TURA 1V8CA 1ODHA 4DUZH 2HHHH 3MEKA 1BMOA 2QQEA 1CHOI 4UXHA 4OO1G 2V53A 2KCXA 2XRCA 1V1HA 2RIJA 1OYVI 2VKCA 2B0UC 1M8BA 4LIJA 4JCVE 2PQ8A 1CGJI 3OVOA 1UG8A 1DT4A 5BR8H 2ANNA 3RU0A 2UZ3A 1I94H 2CJSC 2CTFA 3R5BA 2KMPA 3FSYA 1N34H 2UXDH 2N71A 2UUAH 3BJIA 1X9ZA 1Y1CA 3R5CA 2QQCA 5E3PA 1NXUA 1XX6A 2YUUA 3E2IA 1PQXA 1ULKA 5DAEA 3SGBI 3OL0A 2ODDA 1UUCA 4JI6H 2JA1A 2E73A 4DNCA 1TGSI 4OCHA 9WGAA 1HNZH 4NXNH 2ROWA 3GOXA 1IW4A 4JV5H 2N52A 3QTLD 1HNXH 2K9HA 4E9JA 2NN6G 5EX3A 1R79A 1S03G 2CWGA 3T1HH 2JEBI 2ERWA 2GIVA 1FJGH 2W0TA 2SGEI 3VKEA 4YY3H 5HQ8A 1MJBA 4PDBA 1SGNI 4B3RH 1KMAA 5E3QA 3QAHA 1YU6C 2A1SA 2KMRA 1TOTA 1BUSA 2OPUA 3J80W 3UFFA 1CT0I 4UXIA 3UEYA 3T1YH 2M5XA 2M6QA 1WTJA 7WGAA 4OX9H 1UVFA 2WVJA 4WALA 5FUYA 1FAQA 4H8AA 3R5DA 1X4SA 1HEVA 1OVOA 1P9GA 4B3SH 5A2QW 4X65H 1LR9A 4B8TA 2Z0SA 4GI3C 1LR7A 1SGPI 1F0XA 2PY9A 2UXCH 3UOEA 1N33H 3TOAA 2NU3I 4WANA 4DV4H 1WVNA 2E5LH 3HH2C 5LL6b 1VDDA 2BL5A 4K0KH 2V1CC 1W4RA 2JYYA 2CTEA 3OSSD 2UU9H 1WGCA 1FARA 2NU1I 4DV6H 4DR1H 1IBMH 4FJSA 1X0AA 1XMOH 2PQUA 2SGDI 1KHMA 2A20A 2AXYA
chains in the Genus database with same CATH topology
1Z2IA 2CWHA 2CWFA 2X06A 3I0PA 1XRHA 4FJUA 1V9NA 1NXUA 4H8AA 1VBIA 1S20A 3UOEA 2G8YA 4FJSA 1X0AA 1WTJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Z2I A;  2CWH A;  2CWF A;  2X06 A;  3I0P A;  1XRH A;  4FJU A;  1V9N A;  1NXU A;  4H8A A;  1VBI A;  1S20 A;  3UOE A;  2G8Y A;  4FJS A;  1X0A A;  1WTJ A; 
#chains in the Genus database with same CATH topology
 2LF0 A;  1ZZJ A;  2CTJ A;  2ZM6 H;  1MJA A;  2LEO A;  2LTM A;  2PT7 G;  4JI2 H;  1SGQ I;  2FFM A;  1RFH A;  3GAB A;  1I6U A;  3I0P A;  2VQE H;  1ZZK A;  2FMR A;  4SGB I;  5FUX A;  4DV3 H;  4DV7 H;  2BA0 A;  3NCV A;  1FY7 A;  2KMO A;  1EC6 A;  2B8T A;  2X06 A;  1PJU A;  1XNR H;  1K7U A;  4JI1 H;  1CSO I;  1PTQ A;  3FAU A;  4NBQ A;  5JHW C;  1DS2 I;  2NU0 I;  4JVY A;  3OTO H;  2CWF A;  1MJ9 A;  1VIG A;  2DKV A;  1ZTG A;  1AN1 I;  4LFB H;  2F4V H;  1Q9B A;  4EC5 A;  2UUC H;  4JVH A;  5IT9 W;  5FUW A;  3TO6 A;  1NUB A;  4MPI A;  3V69 A;  4LF9 H;  4UXJ A;  2ELI A;  1TBO A;  3SEK C;  3TJQ A;  1HDL A;  1CT2 I;  2CPQ A;  4JI5 H;  3QWP A;  2UXB H;  3TOB A;  4X64 H;  1WE8 A;  1Y1B A;  2CWH A;  3OXL A;  4NZR M;  2KMQ A;  5CCL A;  4B3M H;  4BA1 I;  1LR8 A;  1K1G A;  4B6D A;  4LF5 H;  3UEJ A;  2JE6 I;  4JI4 H;  2OZU A;  1IY6 A;  1H0Z A;  1M8C A;  4BA2 I;  2GKT I;  2OD1 A;  2HH2 A;  2RC4 A;  1IY5 A;  2WCY A;  4QMF B;  1SGR I;  2ENN A;  3CXL A;  5FUV A;  4A24 A;  4DR4 H;  1MT1 A;  4AQY H;  1TBN A;  3SGQ I;  4JI3 H;  1CE3 A;  1VBI A;  2JZM A;  1X4N A;  2X52 A;  4FKD A;  2K1H A;  1KBF A;  2OPV A;  1DTJ A;  4LF8 H;  1KBE A;  5EX0 A;  1S20 A;  1CGI I;  4DV2 H;  1K7V A;  2CPM A;  1J5E H;  3J7A K;  1HR0 H;  4LF7 H;  2JVZ A;  4DR3 H;  2M8W A;  4AM3 A;  2O4C A;  1UVG A;  1J5K A;  1X4M A;  3B4V C;  4GKJ H;  1VIH A;  2JW6 A;  1R0R I;  3UGL A;  2DGR A;  2ARP F;  3PDN A;  2NU2 I;  4DUY H;  3OET A;  1OMU A;  2WGC A;  1ULM A;  2JXD A;  1Z2I A;  5C0X G;  1Z7K B;  4B8C D;  2Y3M A;  5IWA H;  1CT4 I;  4E1P A;  1Y8F A;  2V1C A;  1N32 H;  2YQP A;  2FNF X;  1MSZ A;  2N1A B;  2F3C I;  2DB6 A;  2J87 A;  2L8E A;  1W3S A;  5LMN H;  4E1R A;  2FPH X;  5JEA G;  2E5R A;  4LFC H;  3OXF A;  1PTR A;  4OD6 A;  1TUA A;  3TO7 A;  2SGP I;  2CTK A;  4LF6 H;  4NXM H;  1YTP A;  1TBQ R;  1K7T A;  4DR2 H;  3OXG A;  1FYB A;  3VDU A;  1AN7 A;  5E3R A;  4X62 H;  1IBK H;  1TBR R;  3AEV B;  4B3T H;  2ORW A;  1N36 H;  4JI0 H;  4AML A;  5K36 G;  3L7Z C;  1SEI A;  1HPT A;  3VDP A;  2QPO A;  2QQD A;  2CTM A;  2CTL A;  1TUS A;  1OMT A;  4LF4 H;  3KY9 A;  1TIH A;  4JI8 H;  2SGQ I;  1ULN A;  4DV0 H;  2YQR A;  2P2R A;  3RF2 A;  4DR6 H;  1PCE A;  5DT9 A;  2JEA I;  1WKX A;  4FJU A;  3SB1 A;  4G08 A;  3TO9 A;  2QQ0 A;  1V1I A;  2DIP A;  4JI7 H;  2OVO A;  1PPF I;  1U5K A;  1XBT A;  2LRR A;  3R5A A;  5CCM A;  1XA6 A;  2HH3 A;  4DV1 H;  4X66 H;  5J8C A;  3JAM W;  2GKR I;  1UHA A;  2BUS A;  5FLX W;  1DS3 I;  2GVI A;  2LUY A;  2G8Y A;  2ANR A;  5J8F A;  3GR5 A;  2ENZ A;  1IBL H;  3UGD A;  1HJA I;  2E3U A;  2MJH A;  3UGI A;  1WGT A;  2VRW B;  3QD7 X;  1SGD I;  1FKA H;  2Y0M A;  3U1K A;  1P9Z A;  1J4W A;  2GKV A;  2JZX A;  5LMU H;  2SGF I;  3J81 W;  3FSX A;  4JYA H;  2JA9 A;  2NU4 I;  4DV5 H;  3VE5 A;  2L7X A;  1XMQ H;  4IFD G;  2N17 A;  5HI7 A;  2UVO A;  4HGU A;  3KDK A;  3FC3 A;  4GKK H;  2ZQE A;  4YHH H;  2LB7 A;  4AIM A;  2QND A;  3KDG A;  2VQF H;  2LTL A;  4OVO A;  1XRH A;  2J9R A;  1V9N A;  4DR5 H;  1X74 A;  4L9M A;  1WHR A;  3D00 A;  4NZT M;  1SGY I;  2OU2 A;  3E59 A;  2UUB H;  1XNQ H;  2X3T A;  1SGE I;  2P6A C;  4KHP H;  2ORV A;  1N13 A;  3GKU A;  2D9I A;  4DR7 H;  1HNW H;  3EZJ A;  4WP4 A;  1ZZI A;  4LFA H;  1TUR A;  1V8C A;  1ODH A;  4DUZ H;  2HHH H;  3MEK A;  1BMO A;  2QQE A;  1CHO I;  4UXH A;  4OO1 G;  2V53 A;  2KCX A;  2XRC A;  1V1H A;  2RIJ A;  1OYV I;  2VKC A;  2B0U C;  1M8B A;  4LIJ A;  4JCV E;  2PQ8 A;  1CGJ I;  3OVO A;  1UG8 A;  1DT4 A;  5BR8 H;  2ANN A;  3RU0 A;  2UZ3 A;  1I94 H;  2CJS C;  2CTF A;  3R5B A;  2KMP A;  3FSY A;  1N34 H;  2UXD H;  2N71 A;  2UUA H;  3BJI A;  1X9Z A;  1Y1C A;  3R5C A;  2QQC A;  5E3P A;  1NXU A;  1XX6 A;  2YUU A;  3E2I A;  1PQX A;  1ULK A;  5DAE A;  3SGB I;  3OL0 A;  2ODD A;  1UUC A;  4JI6 H;  2JA1 A;  2E73 A;  4DNC A;  1TGS I;  4OCH A;  9WGA A;  1HNZ H;  4NXN H;  2ROW A;  3GOX A;  1IW4 A;  4JV5 H;  2N52 A;  3QTL D;  1HNX H;  2K9H A;  4E9J A;  2NN6 G;  5EX3 A;  1R79 A;  1S03 G;  2CWG A;  3T1H H;  2JEB I;  2ERW A;  2GIV A;  1FJG H;  2W0T A;  2SGE I;  3VKE A;  4YY3 H;  5HQ8 A;  1MJB A;  4PDB A;  1SGN I;  4B3R H;  1KMA A;  5E3Q A;  3QAH A;  1YU6 C;  2A1S A;  2KMR A;  1TOT A;  1BUS A;  2OPU A;  3J80 W;  3UFF A;  1CT0 I;  4UXI A;  3UEY A;  3T1Y H;  2M5X A;  2M6Q A;  1WTJ A;  7WGA A;  4OX9 H;  1UVF A;  2WVJ A;  4WAL A;  5FUY A;  1FAQ A;  4H8A A;  3R5D A;  1X4S A;  1HEV A;  1OVO A;  1P9G A;  4B3S H;  5A2Q W;  4X65 H;  1LR9 A;  4B8T A;  2Z0S A;  4GI3 C;  1LR7 A;  1SGP I;  1F0X A;  2PY9 A;  2UXC H;  3UOE A;  1N33 H;  3TOA A;  2NU3 I;  4WAN A;  4DV4 H;  1WVN A;  2E5L H;  3HH2 C;  5LL6 b;  1VDD A;  2BL5 A;  4K0K H;  2V1C C;  1W4R A;  2JYY A;  2CTE A;  3OSS D;  2UU9 H;  1WGC A;  1FAR A;  2NU1 I;  4DV6 H;  4DR1 H;  1IBM H;  4FJS A;  1X0A A;  1XMO H;  2PQU A;  2SGD I;  1KHM A;  2A20 A;  2AXY A; 
#chains in the Genus database with same CATH homology
 1Z2I A;  2CWH A;  2CWF A;  2X06 A;  3I0P A;  1XRH A;  4FJU A;  1V9N A;  1NXU A;  4H8A A;  1VBI A;  1S20 A;  3UOE A;  2G8Y A;  4FJS A;  1X0A A;  1WTJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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