1DKI | Genus

Total Genus 70

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	70
sequence length	335
structure length	303
Chain Sequence	LDKVNLGGELSGSNMYVYNGFVIVSGDKRSPEILGYSTSGSFDVNGKENIASFMESYVEQIKENKKLPVVKSLLDSKGIHYNQGNPYNLLTPVIEKVKPGEQSFVGQHAATGSVATATAQIMKYHNYPNKGLKDYTYTLSSNNPYFNHPKNLFAAISTRQYNWNNILPTYSGRESNVQKMAISELMADVGISVDMDYGPSSGSAGSSRVQRALKENFGYNQSVHQINRGDFSKQDWEAQIDKELSQNQPVYYQGVGKVGGHAFVIDGADGRNFYHVNWGWGGVSDGFFRLDALYQSAVVGIKP

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Toxin
source organism	Streptococcus pyogenes
publication title	Crystal structure of the zymogen form of the group A Streptococcus virulence factor SpeB: an integrin-binding cysteine protease. pubmed doi rcsb
molecule keywords	PYROGENIC EXOTOXIN B ZYMOGEN
total genus	70
structure length	303
sequence length	335
chains with identical sequence	B, C, D
ec nomenclature	ec 3.4.22.10: Streptopain.
pdb deposition date	1999-12-07

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01640	Peptidase_C10	Peptidase C10 family
A	PF13734	Inhibitor_I69	Spi protease inhibitor

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.910.30	Alpha Beta	2-Layer Sandwich	Protein Binding, DinI Protein; Chain A	Protein Binding, DinI Protein; Chain A	1dkiA02
3.90.70.50	Alpha Beta	Alpha-Beta Complex	Cathepsin B; Chain A	Cathepsin B; Chain A	1dkiA01

2JTCA 1PVJA 1DKIA 4D8BA 3BBAA 3BB7A 2UZJA 4D8EA 4RKXA 4D8IA
chains in the Genus database with same CATH superfamily

1MHWA 1GMYA 5CVOB 1MDWA 3OF9A 4G54A 3DF0A 1AIMA 2AVWA 1CQDA 4QRVA 2HD5A 3NHEA 3O65A 3QJ3A 2PADA 4N8WA 2VHFA 1U5IA 3KKUA 3RVXA 4YYUA 3BPFA 2BU3A 2DC7A 1ITOA 2XU1A 2FO5A 1AU2A 2JQFR 1THEA 5CHVA 1CJLA 3CH2X 1KHPA 1PPNA 1QOLA 4CDDB 3H8BA 1CTEA 1FH0A 1AU4A 4OVZA 4QH6A 2Z84A 3MJ5A 5F02A 8PCHA 3KWBX 4KQTA 3H8CA 3O1GA 4W5CA 2XU4A 2R6NA 1PXVA 1TLOA 9PAPA 2UZJA 1AU0A 2FT2A 3S3QA 2B1NA 4BOZA 5EZSA 4PI3A 2IPPB 3KFQA 4I07A 1TU6A 2G8JA 1DF0A 2HWKA 2AYOA 2O6XA 3IV2A 1PPPA 5PADA 4RY2A 4DMYA 2CIOA 1AECA 1YVBA 2VHSA 2E01A 3HHIA 2BTWA 1U9WA 3D6SA 3C0RA 1NLJA 4XZXA 4QBBA 4CDFB 1ICFA 2XU5A 3CH3X 1ATKA 2BDLA 2E03A 3E9SA 1GECE 4XUIA 2OZ2A 2DCDA 1GHHA 3IEJA 4CZWA 3IUTA 3P5XA 3N3GA 4PP1A 3PHWA 2PBHA 2AU1A 2DZYA 3MTNA 1EWMA 4IP3A 1MEMA 1EF7A 2AS8A 4HWYA 1BP4A 3PNRA 1GLOA 4ZUXU 2AUZA 4BQVA 2IBIA 4MZSA 1NB3A 3P5WA 1ME4A 4YYRA 2DC6A 1KXRA 2P86A 1QXPA 3PDFA 1AYUA 5KO3A 2YJ8A 3AI8A 3PHXA 3S3RA 3RNVA 1YZBA 2AYNA 5EZQA 1SG2A 3V6EA 1O0EA 3LXSA 4QRGA 1PE6A 4YYQA 1SP4B 2ARYA 3E1ZB 1Q6KA 2YJCA 1JQPA 2AIMA 1PPDA 2NQIA 1TL9A 1NQCA 3IMAA 2DCCA 3PRMA 2ATOA 2E02A 2HHNA 7PCKA 3PSEA 1STFE 4MZOA 5JA7A 1VSNA 4I04A 1Y4HA 4DMXA 3O0UA 3QT4A 4PP2E 4Q8GA 3F75A 4BS5A 2P0RA 4BS6A 2DC8A 4YYVA 4I05A 4A5UA 3B79A 2HXZA 4XR7A 4QRXA 2YJBA 2WBFX 2NQDB 3GCBA 4GUAA 2CB5A 4BOSA 3ZNHA 1PVJA 5J94A 4CDCB 2PREA 3B21A 1PADA 3PHUA 2ACTA 4Q8HA 1F2BA 3K8UA 2BDZA 3U8EA 1U2MA 2JRIA 5K16A 1PPOA 4YYWA 4RF0A 3PW3A 2OP3A 3CBJA 2DZZA 3ZUAA 4OEMA 1X9YA 1MEGA 3BCNA 4P6GA 1Y08A 3TMPA 4HXDB 1CSBB 2OULA 1F2CA 2DC9A 4FJCA 3MTVA 3OF8A 3KX1A 1CS8A 4BPVA 3MHHA 1MS6A 3I06A 4YV8A 2C0YA 2Y5BA 4AXLA 3MORA 4X6HA 3H7DA 1AYVA 3W31A 2G6DA 1YK8A 3F5VA 1IWDA 3N3KA 1GCBA 2E00A 2F7DA 3USVA 6PADA 1UKFA 2FRQA 2J7QA 2JQGR 4PADA 2FRAA 2AGAA 3KWZA 2DCAA 3H6SA 2B1MA 5EGWA 3TRKA 3RVWA 3K24A 4OELA 4BOQA 1QMYA 2J7QC 1BY8A 1U9VA 1POPA 2AUXA 3N4CA 5CVNB 4X6IA 3V6CA 3PT2A 4BOPA 1KFXL 4OW0A 2FTDA 4M0WA 3W30A 4P16A 1CV8A 3IOQA 1NL6A 3BB7A 1BQIA 1AU3A 4D8EA 2FUDA 3WXGA 1SNKA 5E6JA 1DKIA 1S4VA 4OVZB 4WA6A 3OVZA 2R9OA 3BBAA 4W4UA 2HH5A 2NQGA 1F29A 1YK7A 2R9FA 1YALA 3QSDA 4K7CA 1A6RA 3OVXA 3P5VA 4BSQA 1CVZA 1EWLA 3BC3A 4W5BA 1QDQA 4ZTBA 2G7YA 1PBHA 2FYEA 4YVAA 2FQ9A 2DCBA 4PT5A 1F2AA 1NB5A 2BTWB 3KW9A 3WXEA 1EWOA 1PIPA 1U9QX 4REZA 1M6DA 3IHPA 1CPJA 4P6EA 3OQCA 4CDEB 2NQAA 2F1GA 2R9NA 2DOSA 1CB5A 1PCIA 1KHQA 3C9EA 4N79A 2DJFB 4KLBA 2YJ9A 1DEUA 3P5UA 2R9CA 3WXFA 2GFOA 2XU3A 3BPMA 2H7JA 4FK5A 3LFYA 1BGOA 1K3BB 4RF1A 4MI7A 4FIPA 4IUMA 4WURA 3IFUA 1U9XA 2JTCA 5JZEA 4AXMA 2Y6EA 2PNSA 3HHAA 1MIRA 3I3TA 4D8BA 3PBHA 1VJVA 3HD3A 2R9MA 3MHSA 1ZIVA 1ME3A 3HWNA 4X6JA 3TNXA 2YJ2A 5JH3A 1KFUL 4D8IA 4YYSA 3BY4A 4BOUA 4EVXA 2GHUA 3BOWA 5CHTA 3CBKA 5EF4A 1NPZA 1YT7A 3MP2A 4N4ZA 2G8EA 1AYWA 3K9MA 1HUCB 4R3DA 5CVMA 3PRPA 1ZCMA 1XKGA 4MM3B 2DJGB 3OISA 4RNAA 2FE8A 2P7UA 3ERVA 3RVVA 4MSXA 5FPWA 4RKXA 5A24A 3H89A 3BWKA 3KSEA 3M99A 1EWPA
chains in the Genus database with same CATH topology

3TMPA 4HXDB 3PHWA 4IP3A 3O65A 3MTVA 4ZTBA 4PT5A 2BU3A 2BTWB 5KO3A 3PHXA 3W31A 3RNVA 1YZBA 5EZQA 4REZA 3OQCA 2DOSA 1UKFA 2J7QA 2AGAA 3PRMA 4RF1A 4MI7A 3TRKA 4IUMA 4WURA 3IFUA 4OVZA 4BOQA 3PSEA 2Z84A 3MJ5A 2JTCA 5JZEA 2J7QC 4D8BA 4A5UA 2UZJA 3PT2A 4BOPA 4BOZA 5EZSA 4OW0A 4D8IA 3BY4A 4BOUA 2HWKA 4EVXA 4M0WA 3W30A 4P16A 4GUAA 4BOSA 3ZNHA 1PVJA 3MP2A 3BB7A 3B21A 3PHUA 4D8EA 4R3DA 2BTWA 3PRPA 4MM3B 5E6JA 1DKIA 3C0RA 4XZXA 4RNAA 2FE8A 2JRIA 4OVZB 4RF0A 3BBAA 3E9SA 4RKXA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 2JTC A;  1PVJ A;  1DKI A;  4D8B A;  3BBA A;  3BB7 A;  2UZJ A;  4D8E A;  4RKX A;  4D8I A; 
#chains in the Genus database with same CATH topology
 1MHW A;  1GMY A;  5CVO B;  1MDW A;  3OF9 A;  4G54 A;  3DF0 A;  1AIM A;  2AVW A;  1CQD A;  4QRV A;  2HD5 A;  3NHE A;  3O65 A;  3QJ3 A;  2PAD A;  4N8W A;  2VHF A;  1U5I A;  3KKU A;  3RVX A;  4YYU A;  3BPF A;  2BU3 A;  2DC7 A;  1ITO A;  2XU1 A;  2FO5 A;  1AU2 A;  2JQF R;  1THE A;  5CHV A;  1CJL A;  3CH2 X;  1KHP A;  1PPN A;  1QOL A;  4CDD B;  3H8B A;  1CTE A;  1FH0 A;  1AU4 A;  4OVZ A;  4QH6 A;  2Z84 A;  3MJ5 A;  5F02 A;  8PCH A;  3KWB X;  4KQT A;  3H8C A;  3O1G A;  4W5C A;  2XU4 A;  2R6N A;  1PXV A;  1TLO A;  9PAP A;  2UZJ A;  1AU0 A;  2FT2 A;  3S3Q A;  2B1N A;  4BOZ A;  5EZS A;  4PI3 A;  2IPP B;  3KFQ A;  4I07 A;  1TU6 A;  2G8J A;  1DF0 A;  2HWK A;  2AYO A;  2O6X A;  3IV2 A;  1PPP A;  5PAD A;  4RY2 A;  4DMY A;  2CIO A;  1AEC A;  1YVB A;  2VHS A;  2E01 A;  3HHI A;  2BTW A;  1U9W A;  3D6S A;  3C0R A;  1NLJ A;  4XZX A;  4QBB A;  4CDF B;  1ICF A;  2XU5 A;  3CH3 X;  1ATK A;  2BDL A;  2E03 A;  3E9S A;  1GEC E;  4XUI A;  2OZ2 A;  2DCD A;  1GHH A;  3IEJ A;  4CZW A;  3IUT A;  3P5X A;  3N3G A;  4PP1 A;  3PHW A;  2PBH A;  2AU1 A;  2DZY A;  3MTN A;  1EWM A;  4IP3 A;  1MEM A;  1EF7 A;  2AS8 A;  4HWY A;  1BP4 A;  3PNR A;  1GLO A;  4ZUX U;  2AUZ A;  4BQV A;  2IBI A;  4MZS A;  1NB3 A;  3P5W A;  1ME4 A;  4YYR A;  2DC6 A;  1KXR A;  2P86 A;  1QXP A;  3PDF A;  1AYU A;  5KO3 A;  2YJ8 A;  3AI8 A;  3PHX A;  3S3R A;  3RNV A;  1YZB A;  2AYN A;  5EZQ A;  1SG2 A;  3V6E A;  1O0E A;  3LXS A;  4QRG A;  1PE6 A;  4YYQ A;  1SP4 B;  2ARY A;  3E1Z B;  1Q6K A;  2YJC A;  1JQP A;  2AIM A;  1PPD A;  2NQI A;  1TL9 A;  1NQC A;  3IMA A;  2DCC A;  3PRM A;  2ATO A;  2E02 A;  2HHN A;  7PCK A;  3PSE A;  1STF E;  4MZO A;  5JA7 A;  1VSN A;  4I04 A;  1Y4H A;  4DMX A;  3O0U A;  3QT4 A;  4PP2 E;  4Q8G A;  3F75 A;  4BS5 A;  2P0R A;  4BS6 A;  2DC8 A;  4YYV A;  4I05 A;  4A5U A;  3B79 A;  2HXZ A;  4XR7 A;  4QRX A;  2YJB A;  2WBF X;  2NQD B;  3GCB A;  4GUA A;  2CB5 A;  4BOS A;  3ZNH A;  1PVJ A;  5J94 A;  4CDC B;  2PRE A;  3B21 A;  1PAD A;  3PHU A;  2ACT A;  4Q8H A;  1F2B A;  3K8U A;  2BDZ A;  3U8E A;  1U2M A;  2JRI A;  5K16 A;  1PPO A;  4YYW A;  4RF0 A;  3PW3 A;  2OP3 A;  3CBJ A;  2DZZ A;  3ZUA A;  4OEM A;  1X9Y A;  1MEG A;  3BCN A;  4P6G A;  1Y08 A;  3TMP A;  4HXD B;  1CSB B;  2OUL A;  1F2C A;  2DC9 A;  4FJC A;  3MTV A;  3OF8 A;  3KX1 A;  1CS8 A;  4BPV A;  3MHH A;  1MS6 A;  3I06 A;  4YV8 A;  2C0Y A;  2Y5B A;  4AXL A;  3MOR A;  4X6H A;  3H7D A;  1AYV A;  3W31 A;  2G6D A;  1YK8 A;  3F5V A;  1IWD A;  3N3K A;  1GCB A;  2E00 A;  2F7D A;  3USV A;  6PAD A;  1UKF A;  2FRQ A;  2J7Q A;  2JQG R;  4PAD A;  2FRA A;  2AGA A;  3KWZ A;  2DCA A;  3H6S A;  2B1M A;  5EGW A;  3TRK A;  3RVW A;  3K24 A;  4OEL A;  4BOQ A;  1QMY A;  2J7Q C;  1BY8 A;  1U9V A;  1POP A;  2AUX A;  3N4C A;  5CVN B;  4X6I A;  3V6C A;  3PT2 A;  4BOP A;  1KFX L;  4OW0 A;  2FTD A;  4M0W A;  3W30 A;  4P16 A;  1CV8 A;  3IOQ A;  1NL6 A;  3BB7 A;  1BQI A;  1AU3 A;  4D8E A;  2FUD A;  3WXG A;  1SNK A;  5E6J A;  1DKI A;  1S4V A;  4OVZ B;  4WA6 A;  3OVZ A;  2R9O A;  3BBA A;  4W4U A;  2HH5 A;  2NQG A;  1F29 A;  1YK7 A;  2R9F A;  1YAL A;  3QSD A;  4K7C A;  1A6R A;  3OVX A;  3P5V A;  4BSQ A;  1CVZ A;  1EWL A;  3BC3 A;  4W5B A;  1QDQ A;  4ZTB A;  2G7Y A;  1PBH A;  2FYE A;  4YVA A;  2FQ9 A;  2DCB A;  4PT5 A;  1F2A A;  1NB5 A;  2BTW B;  3KW9 A;  3WXE A;  1EWO A;  1PIP A;  1U9Q X;  4REZ A;  1M6D A;  3IHP A;  1CPJ A;  4P6E A;  3OQC A;  4CDE B;  2NQA A;  2F1G A;  2R9N A;  2DOS A;  1CB5 A;  1PCI A;  1KHQ A;  3C9E A;  4N79 A;  2DJF B;  4KLB A;  2YJ9 A;  1DEU A;  3P5U A;  2R9C A;  3WXF A;  2GFO A;  2XU3 A;  3BPM A;  2H7J A;  4FK5 A;  3LFY A;  1BGO A;  1K3B B;  4RF1 A;  4MI7 A;  4FIP A;  4IUM A;  4WUR A;  3IFU A;  1U9X A;  2JTC A;  5JZE A;  4AXM A;  2Y6E A;  2PNS A;  3HHA A;  1MIR A;  3I3T A;  4D8B A;  3PBH A;  1VJV A;  3HD3 A;  2R9M A;  3MHS A;  1ZIV A;  1ME3 A;  3HWN A;  4X6J A;  3TNX A;  2YJ2 A;  5JH3 A;  1KFU L;  4D8I A;  4YYS A;  3BY4 A;  4BOU A;  4EVX A;  2GHU A;  3BOW A;  5CHT A;  3CBK A;  5EF4 A;  1NPZ A;  1YT7 A;  3MP2 A;  4N4Z A;  2G8E A;  1AYW A;  3K9M A;  1HUC B;  4R3D A;  5CVM A;  3PRP A;  1ZCM A;  1XKG A;  4MM3 B;  2DJG B;  3OIS A;  4RNA A;  2FE8 A;  2P7U A;  3ERV A;  3RVV A;  4MSX A;  5FPW A;  4RKX A;  5A24 A;  3H89 A;  3BWK A;  3KSE A;  3M99 A;  1EWP A; 
#chains in the Genus database with same CATH homology
 3TMP A;  4HXD B;  3PHW A;  4IP3 A;  3O65 A;  3MTV A;  4ZTB A;  4PT5 A;  2BU3 A;  2BTW B;  5KO3 A;  3PHX A;  3W31 A;  3RNV A;  1YZB A;  5EZQ A;  4REZ A;  3OQC A;  2DOS A;  1UKF A;  2J7Q A;  2AGA A;  3PRM A;  4RF1 A;  4MI7 A;  3TRK A;  4IUM A;  4WUR A;  3IFU A;  4OVZ A;  4BOQ A;  3PSE A;  2Z84 A;  3MJ5 A;  2JTC A;  5JZE A;  2J7Q C;  4D8B A;  4A5U A;  2UZJ A;  3PT2 A;  4BOP A;  4BOZ A;  5EZS A;  4OW0 A;  4D8I A;  3BY4 A;  4BOU A;  2HWK A;  4EVX A;  4M0W A;  3W30 A;  4P16 A;  4GUA A;  4BOS A;  3ZNH A;  1PVJ A;  3MP2 A;  3BB7 A;  3B21 A;  3PHU A;  4D8E A;  4R3D A;  2BTW A;  3PRP A;  4MM3 B;  5E6J A;  1DKI A;  3C0R A;  4XZX A;  4RNA A;  2FE8 A;  2JRI A;  4OVZ B;  4RF0 A;  3BBA A;  3E9S A;  4RKX A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1DKIA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations